Detailed information for compound 113147

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 682.754 | Formula: C31H41F3N6O6S
  • H donors: 6 H acceptors: 6 LogP: 2.32 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 3
  • SMILES: CSCC[C@@H](C(=O)N)NC(=O)[C@@H](N(C(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)O)N)CCC(F)(F)F)C)Cc1ccccc1
  • InChi: 1S/C31H41F3N6O6S/c1-40(25(17-19-6-4-3-5-7-19)30(46)38-23(27(36)43)13-15-47-2)26(42)18-37-29(45)24(12-14-31(32,33)34)39-28(44)22(35)16-20-8-10-21(41)11-9-20/h3-11,22-25,41H,12-18,35H2,1-2H3,(H2,36,43)(H,37,45)(H,38,46)(H,39,44)/t22-,23-,24-,25-/m0/s1
  • InChiKey: JQZWFTZURMFCOA-QORCZRPOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus shaker cognate 0.0108 0.0179 0.0178
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0108 0.0179 0.0179
Schistosoma mansoni amine GPCR 0.0055 0.007 0.007
Brugia malayi cation channel family protein 0.0108 0.0179 0.0179
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0108 0.0108
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.007 0.007
Mycobacterium tuberculosis Conserved hypothetical protein 0.1453 0.2923 0.2874
Trypanosoma brucei aurora B kinase 0.0056 0.0071 0.0193
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0245 0.0245
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.007 0.007
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0193 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.007 0.007
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0039 0.0036 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0855 0.1703 0.1703
Trichomonas vaginalis PIKK family atypical protein kinase 0.0462 0.09 0.09
Schistosoma mansoni nAChR subunit 0.0039 0.0036 0.0036
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0055 0.007 0.0189
Echinococcus multilocularis neuropeptide receptor 0.0055 0.007 0.007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0245 0.0245
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0224 0.0415 0.0415
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0108 0.0179 0.0179
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0026
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0163 0.0232
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0055 0.007 0.007
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0039 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0506 0.099 0.099
Schistosoma mansoni opsin-like receptor 0.0055 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0528 0.1035 0.1035
Plasmodium falciparum serine/threonine protein kinase, putative 0.0056 0.0071 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0055 0.007 0.007
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0084 0.0128 0.0128
Toxoplasma gondii PAN domain-containing protein 0.059 0.1162 0.1478
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0056 0.0071 0.0027
Schistosoma mansoni acetylcholine receptor subunit beta 0.0039 0.0036 0.0036
Mycobacterium tuberculosis Conserved protein 0.0074 0.0108 0.0038
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0287 0.0543 0.0543
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Echinococcus granulosus Mastin 0.0074 0.0108 0.0108
Echinococcus multilocularis neuropeptide receptor 0.0055 0.007 0.007
Plasmodium falciparum phd finger protein, putative 0.0059 0.0077 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Loa Loa (eye worm) hypothetical protein 0.0069 0.0098 0.0139
Schistosoma mansoni transient receptor potential channel 0.0168 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus short transient receptor potential channel 6 0.0168 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0036 0.0036
Onchocerca volvulus 0.0588 0.1159 0.1159
Onchocerca volvulus 0.0038 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0154
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0224 0.0415 0.1286
Echinococcus multilocularis neuropeptide receptor A26 0.0055 0.007 0.007
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0179 0.0178
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0114 0.019 0.019
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Schistosoma mansoni purine nucleoside phosphorylase 0.4918 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0462 0.09 0.09
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0224 0.0415 0.0415
Brugia malayi uridine phosphorylase family protein 0.1453 0.2923 0.2923
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0108 0.0179 0.0179
Echinococcus multilocularis glycine receptor subunit beta 0.0084 0.0128 0.0128
Entamoeba histolytica protein kinase , putative 0.0056 0.0071 0.0027
Brugia malayi beta-lactamase family protein 0.0074 0.0108 0.0108
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0084 0.0128 0.0128
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.001 0.0013
Echinococcus granulosus glycine receptor subunit beta 0.0084 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0287 0.0543 0.0543
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0855 0.1703 0.5379
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.0179 0.0227
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.093 0.1857 0.264
Brugia malayi AKH receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0864 0.1722 0.1722
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Echinococcus multilocularis sodium leak channel non selective protein 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Echinococcus granulosus integrin alpha ps 0.0067 0.0095 0.0095
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0055 0.007 0.0189
Loa Loa (eye worm) hypothetical protein 0.0101 0.0163 0.0232
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0153
Echinococcus multilocularis short transient receptor potential channel 6 0.0168 0.03 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0108 0.0179 0.0178
Onchocerca volvulus Putative nachr subunit 0.0157 0.0278 0.0278
Echinococcus multilocularis somatostatin receptor 0.0055 0.007 0.007
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0224 0.0415 0.0415
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0855 0.1703 0.5379
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0108 0.031
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.007 0.007
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0108 0.0179 0.0179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Loa Loa (eye worm) voltage-gated potassium channel 0.0108 0.0179 0.0254
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0588 0.1159 0.1159
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Brugia malayi Bromodomain containing protein 0.0059 0.0077 0.0077
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.007 0.007
Toxoplasma gondii microneme protein MIC17B 0.0038 0.0035 0.0044
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0045 0.005 0.005
Echinococcus multilocularis allatostatin A receptor 0.0055 0.007 0.007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0084 0.0128 0.0128
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0162 0.0287 0.0287
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0045 0.005 0.005
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0035 0.0044
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.007 0.007
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0855 0.1703 0.2116
Schistosoma mansoni protein kinase 0.0056 0.0071 0.0071
Schistosoma mansoni methylthioadenosine phosphorylase 0.1567 0.3157 0.3157
Echinococcus granulosus two pore calcium channel protein 1 0.0108 0.0179 0.0178
Brugia malayi neuropeptide F receptor 0.0055 0.007 0.007
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0099 0.016 0.016
Schistosoma mansoni hypothetical protein 0.0032 0.0022 0.0022
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.1567 0.3157 0.3082
Schistosoma mansoni calcium-activated potassium channel 0.0108 0.0179 0.0178
Schistosoma mansoni hypothetical protein 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0157 0.0278 0.0395
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0055 0.007 0.01
Giardia lamblia Fructose-bisphosphate aldolase 0.061 0.1203 0.1141
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0128 0.0128
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0179 0.0178
Onchocerca volvulus 0.0108 0.0179 0.0178
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0045 0.005 0.005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0084 0.0128 0.0128
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0179 0.0178
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Schistosoma mansoni amine GPCR 0.0055 0.007 0.007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0287 0.0543 0.0543
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.0179 0.0178
Entamoeba histolytica hypothetical protein 0.1453 0.2923 0.3677
Echinococcus multilocularis purine nucleoside phosphorylase 0.4918 1 1
Onchocerca volvulus 0.0045 0.005 0.005
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0157 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Brugia malayi Trypsin family protein 0.0074 0.0108 0.0108
Echinococcus multilocularis 0.0055 0.007 0.007
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0116 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.018 0.0325 0.0462
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0162 0.0287 0.0287
Echinococcus granulosus transmembrane protease serine 3 0.0074 0.0108 0.0108
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0108 0.0179 0.0178
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0089
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.007 0.01
Trypanosoma cruzi nucleoside phosphorylase, putative 0.1453 0.2923 0.9258
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0116 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.1453 0.2923 0.2874
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Leishmania major protein kinase, putative 0.0056 0.0071 0.0193
Echinococcus multilocularis transfer RNA-Gly 0.0108 0.0179 0.0178
Brugia malayi sulfakinin receptor protein 0.0055 0.007 0.007
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0224 0.0415 0.0415
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0245 0.0348
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.3872 0.7864 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.007 0.007
Schistosoma mansoni neuropeptide receptor 0.0055 0.007 0.007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0022 0.0022
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.007 0.007
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.007 0.007
Brugia malayi glutaminase DH11.1 0.0282 0.0532 0.0532
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.007 0.007
Schistosoma mansoni cpg binding protein 0.0031 0.0021 0.0021
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.007 0.007
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0128 0.0128
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0108 0.0179 0.0178
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.007 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0046 0.0113
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.007 0.007
Echinococcus multilocularis g protein coupled receptor 0.0055 0.007 0.007
Onchocerca volvulus 0.0055 0.007 0.007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.007 0.007
Trichomonas vaginalis AGC family protein kinase 0.0099 0.016 0.016
Loa Loa (eye worm) beta-lactamase 0.0074 0.0108 0.0153
Mycobacterium leprae Probable lipase LipE 0.0074 0.0108 0.0038
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0055 0.007 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0116 0.0195 0.0195
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.007 0.007
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0099 0.016 0.0227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0462 0.09 0.09
Loa Loa (eye worm) uridine phosphorylase 0.1453 0.2923 0.4156
Loa Loa (eye worm) hypothetical protein 0.0133 0.0228 0.0325
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0245 0.0245
Schistosoma mansoni voltage-gated ion channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Mycobacterium tuberculosis Conserved protein 0.0074 0.0108 0.0038
Echinococcus granulosus glycine receptor subunit alpha 1 0.0084 0.0128 0.0128
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0195 0.0195
Schistosoma mansoni jumonji domain containing protein 0.0153 0.027 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0681 0.1347 0.4249
Brugia malayi jmjC domain containing protein 0.0073 0.0106 0.0106
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0193 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Leishmania major phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0189
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0085 0.0131 0.0186
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0026
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.007 0.007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0944 0.1886 0.1886
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0055 0.007 0.007
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0917 0.1829 0.2326
Trichomonas vaginalis conserved hypothetical protein 0.1453 0.2923 0.2923
Echinococcus multilocularis integrin alpha 3 0.0115 0.0193 0.0193
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0162 0.0287 0.0881
Onchocerca volvulus 0.0074 0.0108 0.0108
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0855 0.1703 0.1703
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.1128 0.1128
Echinococcus multilocularis orexin receptor type 2 0.0055 0.007 0.007
Loa Loa (eye worm) phosphatidylinositol 3 0.0855 0.1703 0.2421
Onchocerca volvulus 0.0038 0.0035 0.0035
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0056 0.0071 0.0071
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0255 0.0778
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Schistosoma mansoni histamine h1 receptor 0.0055 0.007 0.007
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0855 0.1703 0.5379
Toxoplasma gondii hypothetical protein 0.0108 0.0179 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.016 0.016
Brugia malayi Serotonin receptor 0.0055 0.007 0.007
Onchocerca volvulus 0.0055 0.007 0.007
Echinococcus multilocularis TRP (transient receptor potential) channel 0.014 0.0244 0.0244
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0084 0.0128 0.0128
Echinococcus multilocularis neuropeptide s receptor 0.0055 0.007 0.007
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Onchocerca volvulus 0.0038 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0229 0.0426 0.0426
Echinococcus granulosus neuropeptide receptor 0.0055 0.007 0.007
Echinococcus multilocularis integrin alpha ps 0.0067 0.0095 0.0095
Loa Loa (eye worm) trypsin family protein 0.0074 0.0108 0.0154
Schistosoma mansoni neurotransmitter gated ion channel 0.0045 0.005 0.005
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0266 0.05 0.05
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0108 0.0179 0.0179
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.007 0.007
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.007 0.007
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0157 0.0278 0.0278
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0055 0.007 0.007
Echinococcus multilocularis peregrin 0.0059 0.0077 0.0077
Echinococcus granulosus tm gpcr rhodopsin 0.068 0.1346 0.1346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Echinococcus multilocularis nAChR subunit 0.0084 0.0128 0.0128
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0287 0.0543 0.1692
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0055 0.007 0.007
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0588 0.1159 0.1647
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0056 0.0071 0.0071
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Brugia malayi Fli-1 protein 0.0258 0.0484 0.0484
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Echinococcus multilocularis calcium activated potassium channel 0.011 0.0181 0.0181
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0055 0.007 0.007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.007 0.007
Echinococcus multilocularis shaker cognate 0.0108 0.0179 0.0178
Brugia malayi hypothetical protein 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0162 0.0287 0.0409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.0195 0.0195
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0055 0.007 0.0026
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0224 0.0415 0.0415
Echinococcus multilocularis Zinc finger, PHD finger 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Schistosoma mansoni hypothetical protein 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0116 0.0194 0.0276
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.007 0.0099
Toxoplasma gondii Purine nucleoside phosphorylase 0.3872 0.7864 1
Schistosoma mansoni hypothetical protein 0.0055 0.007 0.007
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0224 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0032 0.0022 0.0032
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0026
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0224 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0153
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0471 0.092 0.0856
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0084 0.0128 0.0183
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0287 0.0543 0.1692
Leishmania major methylthioadenosine phosphorylase, putative 0.1567 0.3157 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Onchocerca volvulus 0.0045 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0108 0.0179 0.0178
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0055 0.007 0.0189
Echinococcus granulosus allatostatin A receptor 0.0055 0.007 0.007
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0108 0.0179 0.0178
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.4918 1 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0084 0.0128 0.0128
Onchocerca volvulus 0.003 0.0018 0.0018
Brugia malayi hypothetical protein 0.0302 0.0574 0.0574
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0055 0.007 0.0089
Trypanosoma brucei uridine phosphorylase 0.1453 0.2923 0.9258
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Onchocerca volvulus 0.0266 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0224 0.0415 0.0415
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.007 0.007
Loa Loa (eye worm) fli-1 protein 0.0258 0.0484 0.0688
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0157 0.0278 0.0278
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0022 0.0022
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.0179 0.0178
Brugia malayi CXXC zinc finger family protein 0.003 0.0018 0.0018
Schistosoma mansoni opsin-like receptor 0.0055 0.007 0.007
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0055 0.007 0.007
Onchocerca volvulus 0.0084 0.0128 0.0128
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.005 0.005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0084 0.0128 0.0128
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0162 0.0287 0.0304
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.007 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0116 0.0195 0.0195
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0055 0.007 0.0089
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0026
Echinococcus granulosus fmrfamide receptor 0.0055 0.007 0.007
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0039 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0077 0.0077
Leishmania major phosphatidylinositol kinase, putative 0.0055 0.007 0.0189
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.007 0.007
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.007 0.007
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0266 0.05 0.0711
Echinococcus granulosus sodium leak channel non selective protein 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0355 0.0682 0.2136
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.007 0.0099
Brugia malayi G-protein coupled receptor 0.0055 0.007 0.007
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0071 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Schistosoma mansoni hypothetical protein 0.0055 0.007 0.007
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0055 0.007 0.0089
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0108 0.0179 0.0178
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.007 0.01
Brugia malayi hypothetical protein 0.0039 0.0036 0.0036
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0084 0.0128 0.0128
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0116 0.0195 0.0195
Schistosoma mansoni transient receptor potential channel 0.0168 0.03 0.03
Echinococcus granulosus voltage gated hydrogen channel 1 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.007 0.007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.007 0.007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0084 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0114 0.019 0.027
Brugia malayi phosphoinositide-dependent protein kinase I 0.0099 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0227 0.0421 0.0599
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0021 0.0000026127 0.0000037144
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.0587 0.1831
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0035 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.0179 0.0178
Brugia malayi serine/threonine-protein kinase 6 0.0056 0.0071 0.0071
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.1567 0.3157 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0461 0.0898 0.0898
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0245 0.0245
Entamoeba histolytica hypothetical protein 0.0055 0.007 0.0026
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0287 0.0543 0.1692
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.0179 0.0178
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.0587 0.1831
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0189
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0084 0.0128 0.0128
Schistosoma mansoni integrin alpha 0.015 0.0264 0.0264
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0108 0.0038
Brugia malayi Trypsin family protein 0.0588 0.1159 0.1159
Echinococcus multilocularis glycoprotein Antigen 5 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Loa Loa (eye worm) AUR protein kinase 0.0056 0.0071 0.0101
Schistosoma mansoni neurotransmitter gated ion channel 0.0039 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0125 0.0213 0.0213
Schistosoma mansoni ryanodine receptor related 0.0108 0.0179 0.0178
Brugia malayi hypothetical protein 0.0039 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0069 0.0098 0.0098
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.061 0.1203 0.1476
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0162 0.0287 0.0881
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.007 0.007
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0116 0.0195 0.0195
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0255 0.0778
Leishmania major nucleoside phosphorylase-like protein 0.1453 0.2923 0.9258
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0224 0.0415 0.059
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.007
Echinococcus multilocularis purine nucleoside phosphorylase 0.4918 1 1
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0056 0.0071 0.0027
Echinococcus multilocularis purine nucleoside phosphorylase 0.3466 0.7034 0.7034
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0125 0.0213 0.0213
Echinococcus multilocularis integrin alpha ps 0.0067 0.0095 0.0095
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0855 0.1703 0.1703
Loa Loa (eye worm) hypothetical protein 0.0073 0.0106 0.015
Brugia malayi excitatory GABA receptor EXP-1A 0.0084 0.0128 0.0128
Echinococcus multilocularis cpg binding protein 0.0031 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.3466 0.7034 1
Echinococcus multilocularis conserved hypothetical protein 0.0108 0.0179 0.0178
Schistosoma mansoni methylthioadenosine phosphorylase 0.1453 0.2923 0.2923
Onchocerca volvulus 0.0038 0.0035 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.007 0.007
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0012 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0128 0.0128
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0089
Loa Loa (eye worm) hypothetical protein 0.02 0.0366 0.052
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0179 0.0178
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.007 0.007
Brugia malayi hypothetical protein 0.0108 0.0179 0.0179
Onchocerca volvulus Huntingtin homolog 0.0133 0.0228 0.0228
Onchocerca volvulus 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Onchocerca volvulus 0.0055 0.007 0.007
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0189
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0055 0.007 0.007
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0298 0.0566 0.0499
Schistosoma mansoni biogenic amine receptor 0.0055 0.007 0.007
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.007 0.007
Onchocerca volvulus 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.007 0.007
Brugia malayi Dopamine receptor protein 2 0.0055 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.1453 0.2923 0.2923
Toxoplasma gondii hypothetical protein 0.0108 0.0179 0.0227
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.007 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Echinococcus multilocularis GPCR, family 2 0.0032 0.0022 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.007 0.007
Onchocerca volvulus 0.0055 0.007 0.007
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.0179 0.0178
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0108 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0153
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.007 0.007
Echinococcus granulosus nAChR subunit 0.0045 0.005 0.005
Echinococcus multilocularis hyperpolarization activated cyclic 0.0116 0.0195 0.0195
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0084 0.0128 0.0128
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.1346 0.1346
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0114 0.0191 0.0122
Echinococcus granulosus transient receptor potential gamma protein 0.02 0.0366 0.0366
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.0179 0.0227
Echinococcus granulosus geminin 0.0528 0.1035 0.1035
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0084 0.0128 0.0128
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.3872 0.7864 1
Leishmania major hypothetical protein, conserved 0.0055 0.007 0.0189
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0116 0.0195 0.0277
Echinococcus multilocularis hyperpolarization activated cyclic 0.0116 0.0195 0.0195
Toxoplasma gondii target of rapamycin (TOR), putative 0.0636 0.1256 0.1597
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.3872 0.7864 0.7864
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Leishmania major hypothetical protein, unknown function 0.0108 0.0179 0.0535
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0055 0.007 0.0026
Brugia malayi ion channel NompC 0.0108 0.0179 0.0179
Schistosoma mansoni transient receptor potential channel 4 0.02 0.0366 0.0366
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0108 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0175 0.0175
Echinococcus multilocularis Mastin 0.0074 0.0108 0.0108
Giardia lamblia Aurora kinase 0.0056 0.0071 0.0001
Echinococcus granulosus GA binding protein alpha chain 0.0085 0.0131 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.1346 0.1346
Echinococcus granulosus ephrin type A receptor 4 A 0.0064 0.0089 0.0089
Onchocerca volvulus 0.0038 0.0035 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0189
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0511 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Leishmania major hypothetical protein, conserved 0.0074 0.0108 0.031
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.005 0.005
Echinococcus multilocularis ephrin type A receptor 4 A 0.0064 0.0089 0.0089
Echinococcus granulosus cpg binding protein 0.0031 0.0021 0.0021
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0055 0.007 0.007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0108 0.0038
Loa Loa (eye worm) hypothetical protein 0.0064 0.0087 0.0124
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0055 0.007 0.0189
Loa Loa (eye worm) hypothetical protein 0.006 0.0079 0.0112
Brugia malayi voltage-dependent calcium channel 0.0108 0.0179 0.0179
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0074 0.0108 0.0108
Schistosoma mansoni amine GPCR 0.0055 0.007 0.007
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.007 0.007
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0055 0.007 0.007
Loa Loa (eye worm) AUR protein kinase 0.0056 0.0071 0.0101
Brugia malayi N-terminal motif family protein 0.0364 0.0702 0.0702
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0116 0.0195 0.0195
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0108 0.0179 0.0178
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0108 0.0108
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.007 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Schistosoma mansoni adenoreceptor 0.0055 0.007 0.007
Brugia malayi SWIB/MDM2 domain containing protein 0.0021 0.0000026127 0.0000026127
Echinococcus multilocularis voltage gated potassium channel 0.0116 0.0195 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0511 0.1 0.1
Onchocerca volvulus 0.0055 0.007 0.007
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0084 0.0128 0.0128
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0084 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0153
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.007 0.007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.007 0.007
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.3466 0.7034 0.7034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0555 0.1091 0.1091
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0035 0.005
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.007 0.007
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.4918 1 1
Echinococcus multilocularis sex peptide receptor 0.0055 0.007 0.007
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.4918 1 1
Brugia malayi hypothetical protein 0.0026 0.001 0.001
Echinococcus granulosus hypothetical protein 0.0108 0.0179 0.0178
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0032 0.0022 0.0022
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0074 0.0108 0.0108
Echinococcus granulosus voltage gated potassium channel 0.0116 0.0195 0.0195
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0108 0.0179 0.0178
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0101 0.0163 0.0232
Schistosoma mansoni neuropeptide receptor 0.0055 0.007 0.007
Loa Loa (eye worm) brahma associated protein 0.0021 0.0000026127 0.0000037144
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0179 0.0178
Echinococcus granulosus voltage gated potassium channel 0.0108 0.0179 0.0178
Onchocerca volvulus 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) voltage-gated calcium channel 0.0108 0.0179 0.0254
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0055 0.007 0.007
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0287 0.0543 0.1692
Trichomonas vaginalis PIKK family atypical protein kinase 0.0855 0.1703 0.1703
Trichomonas vaginalis PIKK family atypical protein kinase 0.0462 0.09 0.09
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.007 0.007
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0108 0.0038
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0179 0.0178
Brugia malayi Ets-domain containing protein 0.0085 0.0131 0.0131
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0116 0.0195 0.0195
Toxoplasma gondii PAN domain-containing protein 0.059 0.1162 0.1478
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0108 0.0108
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0108 0.0179 0.0179
Echinococcus granulosus hyperpolarization activated cyclic 0.0116 0.0195 0.0195
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.0179 0.0178
Echinococcus granulosus nAChR subunit 0.0084 0.0128 0.0128
Echinococcus multilocularis fmrfamide receptor 0.0055 0.007 0.007
Echinococcus multilocularis GA binding protein alpha chain 0.0085 0.0131 0.0131
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0162 0.0287 0.0287
Schistosoma mansoni serine-type protease inhibitor 0.0442 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Echinococcus multilocularis voltage gated potassium channel 0.0108 0.0179 0.0178
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0116 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0162 0.0287 0.0287
Plasmodium falciparum purine nucleoside phosphorylase 0.3872 0.7864 1
Brugia malayi serine/threonine kinase 12 0.0056 0.0071 0.0071
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1453 0.2923 0.2923
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0035 0.005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0593 0.1168 0.1168
Brugia malayi Cyclic-nucleotide gated cation channel 0.0116 0.0195 0.0195
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.007 0.007
Onchocerca volvulus 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Schistosoma mansoni acetylcholine receptor-related 0.0039 0.0036 0.0036
Schistosoma mansoni cpg binding protein 0.003 0.0018 0.0018
Toxoplasma gondii subtilisin SUB12 0.0038 0.0035 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0108 0.0137
Toxoplasma gondii hypothetical protein 0.005 0.0059 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0099 0.016 0.016
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0205 0.0292
Brugia malayi Dopamine receptor protein 1 0.0055 0.007 0.007
Echinococcus granulosus enteropeptidase 0.0074 0.0108 0.0108
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0055 0.007 0.0089
Toxoplasma gondii microneme protein, putative 0.0038 0.0035 0.0044
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0108 0.0179 0.0178
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0855 0.1703 0.5379
Brugia malayi Ets-domain containing protein 0.0085 0.0131 0.0131
Loa Loa (eye worm) phosphatidylinositol 3 0.0287 0.0543 0.0772
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.007 0.007
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0108 0.0179 0.0179
Onchocerca volvulus 0.0084 0.0128 0.0128
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0106 0.0151
Echinococcus granulosus two pore calcium channel protein 2 0.0108 0.0179 0.0178
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0855 0.1703 0.5379
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0084 0.0128 0.0183
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0084 0.0128 0.0183
Onchocerca volvulus 0.0064 0.0087 0.0087
Brugia malayi brahma associated protein 60 kDa 0.0021 0.0000026127 0.0000026127
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0046 0.0113
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0039 0.0036 0.0036
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0055 0.007 0.0089
Schistosoma mansoni hypothetical protein 0.0032 0.0022 0.0022
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0308 0.0587 0.1831
Entamoeba histolytica hypothetical protein 0.0162 0.0287 0.0304
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0074 0.0108 0.0108
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.4918 1 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0108 0.0179 0.0179
Plasmodium vivax hypothetical protein, conserved 0.0055 0.007 0.0089
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0039 0.0036 0.0036
Echinococcus granulosus glycine receptor subunit alpha 1 0.0084 0.0128 0.0128
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Echinococcus granulosus aurora kinase A 0.0056 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.1346 0.1346
Echinococcus multilocularis fmrfamide receptor 0.0055 0.007 0.007
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0055 0.007 0.007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.007 0.007
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Onchocerca volvulus 0.0039 0.0036 0.0036
Echinococcus granulosus integrin alpha ps 0.0032 0.0023 0.0023
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0224 0.0415 0.1286
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0179 0.0178
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0056 0.0071 0.009
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0035 0.0044
Echinococcus granulosus tachykinin peptides receptor 99D 0.0055 0.007 0.007
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Mycobacterium tuberculosis Hypothetical protein 0.1453 0.2923 0.2874
Onchocerca volvulus 0.0074 0.0108 0.0108
Mycobacterium ulcerans hypothetical protein 0.0162 0.0289 0.0183
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.007 0.007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.007 0.007
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.0179 0.0178
Leishmania major mitochondrial DNA polymerase beta 0.0308 0.0587 0.1831
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0195 0.0195
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0039 0.0036 0.0036
Toxoplasma gondii transporter, cation channel family protein 0.0224 0.0415 0.0528
Echinococcus multilocularis integrin alpha ps 0.0032 0.0023 0.0023
Schistosoma mansoni biogenic amine receptor 0.0055 0.007 0.007
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0099 0.016 0.0227
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.1453 0.2923 0.2846
Schistosoma mansoni cpg binding protein 0.0031 0.0021 0.0021
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0179 0.0178
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0055 0.007 0.0089
Plasmodium vivax hypothetical protein 0.0055 0.007 0.0089
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.0145 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Brugia malayi brahma associated protein 60 kDa 0.0021 0.0000026127 0.0000026127
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.005 0.005
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1453 0.2923 0.2923
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0108 0.031
Echinococcus multilocularis purine nucleoside phosphorylase 0.3466 0.7034 0.7034
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0157 0.0278 0.0278
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0179 0.0178
Toxoplasma gondii microneme protein MIC17A 0.0038 0.0035 0.0044
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0108 0.0153
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Loa Loa (eye worm) phosphatidylinositol kinase 0.0055 0.007 0.0099
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0077 0.011
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0035 0.0044
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0298 0.0566 0.0463
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Toxoplasma gondii aurora kinase 0.0056 0.0071 0.009
Entamoeba histolytica protein kinase rad3, putative 0.0162 0.0287 0.0304
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0055 0.007 0.007
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0038 0.0035 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.068 0.1346 0.1346
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0077 0.0077
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0245 0.0245
Onchocerca volvulus 0.0055 0.007 0.007
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Schistosoma mansoni serine-type protease inhibitor 0.0442 0.0859 0.0859
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.007 0.007
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0077 0.0098
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0189
Echinococcus multilocularis serotonin receptor 0.0055 0.007 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.0179 0.0178
Brugia malayi ORL1-like opioid receptor 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0461 0.0898 0.0898
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0179 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0084 0.0128 0.0128
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.1567 0.3157 0.4488
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0055 0.007 0.0089
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0855 0.1703 0.1703
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus short transient receptor potential channel 6 0.0168 0.03 0.03
Onchocerca volvulus 0.0055 0.007 0.007
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0055 0.007 0.007
Echinococcus granulosus glycoprotein Antigen 5 0.0074 0.0108 0.0108
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0108 0.0038
Brugia malayi follicle stimulating hormone receptor 0.0055 0.007 0.007
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Schistosoma mansoni myosin xvIII 0.0055 0.007 0.007
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0046 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0855 0.1703 0.1703
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0084 0.0128 0.0128
Giardia lamblia UPL-1 0.1453 0.2923 0.2874
Onchocerca volvulus 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.007 0.007
Onchocerca volvulus 0.0038 0.0035 0.0035
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0179 0.0178
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Echinococcus granulosus methylthioadenosine phosphorylase 0.1567 0.3157 0.3157
Schistosoma mansoni hypothetical protein 0.0528 0.1035 0.1035
Echinococcus multilocularis serotonin receptor 0.0055 0.007 0.007
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.0179 0.0227
Echinococcus granulosus calcium activated potassium channel 0.011 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0116 0.0195 0.0277
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.007 0.007
Echinococcus granulosus somatostatin receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Leishmania major calcium channel protein, putative,ion transporter, putative 0.1399 0.2815 0.8912
Loa Loa (eye worm) hypothetical protein 0.0364 0.0702 0.0997
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0077 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0039 0.0036 0.0036
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0055 0.007 0.0089
Echinococcus granulosus g protein coupled receptor 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0162 0.0287 0.0287
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0125 0.0213 0.0213
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.001 0.0013
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0084 0.0128 0.0128
Loa Loa (eye worm) integrin alpha pat-2 0.0232 0.0431 0.0612
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0055 0.007 0.007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Echinococcus granulosus g-protein coupled receptor 0.0055 0.007 0.007
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0055 0.007 0.007
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0035 0.005
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0282
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0084 0.0128 0.0183
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0153
Echinococcus multilocularis voltage dependent calcium channel 0.0224 0.0415 0.0415
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0245 0.0245
Brugia malayi larval opioid receptor 0.0055 0.007 0.007
Brugia malayi serine/threonine protein kinase 6 0.0056 0.0071 0.0071
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0055 0.007 0.0089
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0108 0.0179 0.0178
Schistosoma mansoni hypothetical protein 0.0074 0.0108 0.0108
Brugia malayi Integrin alpha pat-2 precursor 0.015 0.0264 0.0264
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0077 0.0077
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0162 0.0287 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0325 0.0325
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0108 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0072 0.0091
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0055 0.007 0.0189
Echinococcus granulosus potassium large conductance calcium activated 0.0108 0.0179 0.0178
Onchocerca volvulus 0.0055 0.007 0.007
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0055 0.007 0.007
Echinococcus granulosus neuropeptide receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.007 0.007
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.007 0.007
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0162 0.0287 0.0881
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0022 0.0032
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.007 0.007
Echinococcus multilocularis geminin 0.0528 0.1035 0.1035
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) acetylcholine receptor protein 0.0039 0.0036 0.0051
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Echinococcus granulosus serine protein kinase ATM 0.0162 0.0287 0.0287
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.007 0.007
Onchocerca volvulus 0.0055 0.007 0.007
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0116 0.0195 0.0195
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.007 0.007
Onchocerca volvulus 0.0038 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Echinococcus multilocularis two pore calcium channel protein 2 0.0108 0.0179 0.0178
Entamoeba histolytica protein kinase, putative 0.0099 0.016 0.0141
Echinococcus multilocularis g protein coupled receptor 0.0055 0.007 0.007
Brugia malayi Trypsin-like protease protein 5 0.0074 0.0108 0.0108
Schistosoma mansoni vesicular amine transporter 0.0108 0.0179 0.0178
Treponema pallidum pfs protein (pfs) 0.1453 0.2923 0.2583
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.001 0.0013
Schistosoma mansoni ets-related 0.0258 0.0484 0.0484
Schistosoma mansoni ephrin receptor 0.0064 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0108 0.0038
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0163 0.0163
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0287 0.0543 0.0543
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Treponema pallidum uridine phosphorylase (udp) 0.3872 0.7864 1
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.1346 0.1346
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0071 0.0071
Onchocerca volvulus 0.0055 0.007 0.007
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1453 0.2923 0.2923
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0055 0.007 0.007
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.007 0.0099
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.1453 0.2923 0.3677
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0055 0.007 0.007
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0055 0.007 0.0189
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0116 0.0195 0.0195
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0065 0.0174
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0036 0.0036
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.007 0.01
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0055 0.007 0.007
Echinococcus granulosus voltage dependent calcium channel 0.0224 0.0415 0.0415
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0055 0.007 0.007
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0108 0.0179 0.0178
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0108 0.0108
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Entamoeba histolytica protein kinase, putative 0.0056 0.0071 0.0027
Onchocerca volvulus 0.0055 0.007 0.007
Echinococcus multilocularis enteropeptidase 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0059 0.0077 0.011
Brugia malayi hypothetical protein 0.0039 0.0036 0.0036
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0179 0.0178
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.007 0.007
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0055 0.007 0.007
Onchocerca volvulus 0.0039 0.0036 0.0036
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0108 0.0179 0.0179
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0302 0.0574 0.0816
Schistosoma mansoni voltage-gated cation channel 0.0224 0.0415 0.0415
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0157 0.0278 0.0278
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0855 0.1703 0.5379
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.007 0.007
Brugia malayi jmjC domain containing protein 0.0193 0.0351 0.0351
Onchocerca volvulus 0.0266 0.05 0.05
Toxoplasma gondii microneme protein MIC17C 0.0038 0.0035 0.0044
Loa Loa (eye worm) glutaminase 2 0.0282 0.0532 0.0757
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.3872 0.7864 0.7864
Echinococcus granulosus neuropeptide receptor A26 0.0055 0.007 0.007
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0046 0.0113
Toxoplasma gondii phosphorylase family protein 0.1453 0.2923 0.3717
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0224 0.0415 0.0415
Echinococcus granulosus hypothetical protein 0.0055 0.007 0.007
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0099 0.016 0.016
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0116 0.0195 0.0195
Echinococcus granulosus GPCR family 2 0.0032 0.0022 0.0022
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0224 0.0415 0.0415
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.007 0.007
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0018 0.0025
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.007 0.007
Echinococcus granulosus ryanodine receptor 44f 0.0108 0.0179 0.0178
Echinococcus multilocularis traf and tnf receptor associated protein 0.0944 0.1886 0.1885
Onchocerca volvulus 0.0055 0.007 0.007
Brugia malayi FAT domain containing protein 0.0125 0.0213 0.0213
Brugia malayi Cation transporter family protein 0.0084 0.0128 0.0128
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.1453 0.2923 0.3677
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Schistosoma mansoni 60S ribosomal protein L21 0.0108 0.0179 0.0178
Schistosoma mansoni purine nucleoside phosphorylase 0.4918 1 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Loa Loa (eye worm) AUR protein kinase 0.0056 0.0071 0.0101
Entamoeba histolytica hypothetical protein 0.0055 0.007 0.0026
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0055 0.007 0.007
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0255 0.0778
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0055 0.007 0.0189
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.0179 0.0227
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.0124 0.0124
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0039 0.0036 0.0051
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0266 0.05 0.05
Echinococcus multilocularis purine nucleoside phosphorylase 0.4918 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.007 0.007
Schistosoma mansoni biogenic amine receptor 0.0055 0.007 0.007
Brugia malayi olfactory channel protein osm-9 0.0108 0.0179 0.0179
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.007 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0071 0.0071
Loa Loa (eye worm) TK/EPH protein kinase 0.0082 0.0125 0.0177
Toxoplasma gondii hypothetical protein 0.0038 0.0035 0.0044
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0195 0.0195
Echinococcus granulosus integrin alpha 3 0.0115 0.0193 0.0193
Echinococcus granulosus neuropeptide s receptor 0.0055 0.007 0.007
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.007 0.007
Schistosoma mansoni two-pore calcium channel 0.0108 0.0179 0.0178
Brugia malayi neuropeptide F receptor 0.0055 0.007 0.007
Schistosoma mansoni cercarial elastase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) ACC-1 protein 0.0084 0.0128 0.0183
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.007 0.01
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0298 0.0566 0.0499
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Echinococcus multilocularis two pore calcium channel protein 1 0.0108 0.0179 0.0178
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0084 0.0128 0.0128
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0108 0.0179 0.0179
Schistosoma mansoni amine GPCR 0.0055 0.007 0.007
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0404 0.0783 0.2455
Schistosoma mansoni nAChR subunit 0.0039 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.073 0.1448 0.1448
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0855 0.1703 0.1703
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0179 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.1346 0.1346
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0162 0.0287 0.0287
Echinococcus multilocularis purine nucleoside phosphorylase 0.4918 1 1
Loa Loa (eye worm) ion channel NompC 0.0108 0.0179 0.0254
Onchocerca volvulus 0.0038 0.0035 0.0035
Schistosoma mansoni gabp alpha 0.0085 0.0131 0.0131
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.061 0.1203 0.1203
Echinococcus granulosus traf and tnf receptor associated protein 0.0944 0.1886 0.1885
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0084 0.0128 0.0128
Loa Loa (eye worm) voltage-dependent calcium channel 0.0224 0.0415 0.059
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0055 0.007 0.0189
Brugia malayi cation channel family protein 0.0108 0.0179 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Echinococcus granulosus orexin receptor type 2 0.0055 0.007 0.007
Giardia lamblia PHD finger protein 15 0.0059 0.0077 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0195 0.0195
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.007 0.007
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0103 0.0103
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.0145 0.0145
Onchocerca volvulus 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0116 0.0194 0.0276
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.1453 0.2923 0.2874
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0026
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.007 0.007
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0342 0.0656 0.0932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0461 0.0898 0.0898
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Schistosoma mansoni hypothetical protein 0.0055 0.007 0.007
Trichomonas vaginalis AGC family protein kinase 0.0099 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0289 0.022
Brugia malayi G-protein coupled receptor 0.0055 0.007 0.007
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.007 0.01
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0106 0.0106
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0084 0.0128 0.0128
Onchocerca volvulus 0.0055 0.007 0.007
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0179 0.0178
Toxoplasma gondii FATC domain-containing protein 0.0162 0.0287 0.0366
Entamoeba histolytica protein kinase, putative 0.0056 0.0071 0.0027
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.007 0.007
Schistosoma mansoni voltage-dependent calcium channel 0.0108 0.0179 0.0178
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.0179 0.0178
Echinococcus multilocularis serine protein kinase ATM 0.0162 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0128 0.0128
Onchocerca volvulus 0.0514 0.1008 0.1007
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0116 0.0195 0.0195
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.007 0.01
Leishmania major hypothetical protein, unknown function 0.0055 0.007 0.0189
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0055 0.007 0.007
Schistosoma mansoni transient receptor potential channel 0.02 0.0366 0.0366
Loa Loa (eye worm) voltage-gated potassium channel 0.0108 0.0179 0.0254
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0055 0.007 0.0099
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.007 0.007
Mycobacterium tuberculosis Conserved protein 0.0074 0.0108 0.0038
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Toxoplasma gondii PAN/Apple domain-containing protein 0.0038 0.0035 0.0044
Toxoplasma gondii hypothetical protein 0.0038 0.0035 0.0044
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Echinococcus granulosus glycine receptor subunit beta 0.0084 0.0128 0.0128
Trypanosoma cruzi target of rapamycin kinase 3 0.0681 0.1347 0.4249
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus jumonji domain containing protein 0.0082 0.0124 0.0124
Echinococcus multilocularis ryanodine receptor 44f 0.0108 0.0179 0.0178
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0157 0.0278 0.0278
Brugia malayi Melatonin receptor type 1A 0.0055 0.007 0.007
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.0179 0.0178
Brugia malayi Serotonin receptor 0.0055 0.007 0.007
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0084 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Schistosoma mansoni neuropeptide receptor 0.0055 0.007 0.007
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0116 0.0195 0.0277
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Leishmania major phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0189
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0195 0.0195
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0108 0.0179 0.0178
Onchocerca volvulus 0.0074 0.0108 0.0108
Onchocerca volvulus 0.0038 0.0035 0.0035
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0179 0.0178
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.1567 0.3157 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0085 0.0085
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.1453 0.2923 0.2874
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0128 0.0128
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0084 0.0128 0.0128
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0116 0.0195 0.0277
Echinococcus multilocularis aurora kinase A 0.0056 0.0071 0.0071
Brugia malayi PHD-finger family protein 0.0059 0.0077 0.0077
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.007 0.01
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.007 0.007
Brugia malayi Trypsin family protein 0.0074 0.0108 0.0108
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0108 0.0038
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0855 0.1703 0.2116
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0033
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.007 0.0099
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0055 0.007 0.007
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0055 0.007 0.007
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0039 0.0036 0.0036
Brugia malayi beta-lactamase family protein 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.0033
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0107 0.0175 0.0249
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0077 0.0098
Mycobacterium leprae probable uridine phosphorylase 0.1453 0.2923 0.2874
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0108 0.0179 0.0179
Chlamydia trachomatis AMP nucleosidase 0.1453 0.2923 1
Schistosoma mansoni methylthioadenosine phosphorylase 0.1567 0.3157 0.3157
Brugia malayi hypothetical protein 0.0133 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0154
Echinococcus multilocularis transient receptor potential gamma protein 0.02 0.0366 0.0366
Brugia malayi putative neuropeptide receptor 0.0055 0.007 0.007
Trypanosoma cruzi aurora B kinase, putative 0.0056 0.0071 0.0193
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0055 0.007 0.007
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0179 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0287 0.0543 0.0543
Leishmania major phosphatidylinositol 3-kinase, putative 0.0287 0.0543 0.1692
Toxoplasma gondii microneme protein MIC4 0.0038 0.0035 0.0044
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0108 0.0038
Trypanosoma cruzi nucleoside phosphorylase, putative 0.1453 0.2923 0.9258
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus granulosus sodium channel protein 0.1399 0.2815 0.2815
Trichomonas vaginalis PIKK family atypical protein kinase 0.0511 0.1 0.1
Echinococcus granulosus voltage dependent calcium channel 0.0224 0.0415 0.0415
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0084 0.0128 0.0128
Loa Loa (eye worm) GABA receptor subunit 0.0045 0.005 0.007
Schistosoma mansoni integrin alpha-ps 0.0035 0.0029 0.0029
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.007 0.007
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0154
Loa Loa (eye worm) hypothetical protein 0.0588 0.1159 0.1647
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0108 0.0179 0.0535
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Onchocerca volvulus 0.0302 0.0574 0.0574
Onchocerca volvulus 0.0266 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Echinococcus granulosus g protein coupled receptor 0.0055 0.007 0.007
Toxoplasma gondii ABC1 family protein 0.0074 0.0108 0.0137
Loa Loa (eye worm) hypothetical protein 0.0224 0.0415 0.059
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0287 0.0543 0.1692
Brugia malayi RE15519p 0.0055 0.007 0.007
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Brugia malayi Protein kinase domain containing protein 0.0343 0.0658 0.0658
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Brugia malayi hypothetical protein 0.0039 0.0036 0.0036
Schistosoma mansoni opsin-like receptor 0.0055 0.007 0.007
Echinococcus granulosus TRP transient receptor potential channel 0.014 0.0244 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0506 0.099 0.099
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0035 0.005
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0055 0.007 0.0189
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0364 0.0702 0.0702
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0154
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0036 0.0036
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0116 0.0195 0.0195
Mycobacterium ulcerans glutaminase 0.0282 0.0532 0.0429
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Schistosoma mansoni uridine phosphorylase 0.1453 0.2923 0.2923
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0108 0.0179 0.0535
Brugia malayi beta-lactamase 0.0074 0.0108 0.0108
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0055 0.007 0.0089
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0157 0.0278 0.0278
Onchocerca volvulus 0.0055 0.007 0.007
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.007 0.007
Onchocerca volvulus Alhambra homolog 0.0059 0.0077 0.0077
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0084 0.0128 0.0183
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Onchocerca volvulus 0.0055 0.007 0.007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.061 0.1203 0.1476
Echinococcus multilocularis methylthioadenosine phosphorylase 0.1567 0.3157 0.3157
Onchocerca volvulus 0.0038 0.0035 0.0035
Echinococcus multilocularis sodium channel protein 0.1399 0.2815 0.2815
Echinococcus multilocularis potassium large conductance calcium activated 0.0108 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Onchocerca volvulus 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0039 0.0036 0.0036
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0116 0.0195 0.0195
Brugia malayi Dopamine receptor 0.0055 0.007 0.007
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0055 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0287 0.0543 0.0543
Echinococcus granulosus serotonin receptor 0.0055 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Schistosoma mansoni glutaminase 0.0282 0.0532 0.0532
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0084 0.0128 0.0128
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0108 0.0179 0.0178
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.007 0.007
Echinococcus multilocularis short transient receptor potential channel 6 0.0168 0.03 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0287 0.0543 0.0543
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0287 0.0543 0.0543
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Echinococcus granulosus sex peptide receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Leishmania major phosphatidylinositol kinase related protein, putative 0.0055 0.007 0.0189
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0084 0.0128 0.0128
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0163 0.0163
Loa Loa (eye worm) LGC-31 protein 0.0084 0.0128 0.0183
Echinococcus multilocularis purine nucleoside phosphorylase 0.4918 1 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Loa Loa (eye worm) ryanodine receptor 0.0108 0.0179 0.0254
Giardia lamblia GTOR 0.0855 0.1703 0.1645
Trichomonas vaginalis esterase, putative 0.0074 0.0108 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Echinococcus granulosus uridine phosphorylase 1 0.1453 0.2923 0.2923
Loa Loa (eye worm) hypothetical protein 0.0038 0.0035 0.005
Trypanosoma cruzi nucleoside phosphorylase, putative 0.1453 0.2923 0.9258
Brugia malayi Trypsin family protein 0.0074 0.0108 0.0108
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0056 0.0071 0.0027
Echinococcus granulosus hyperpolarization activated cyclic 0.0116 0.0195 0.0195
Echinococcus multilocularis uridine phosphorylase 1 0.1453 0.2923 0.2923
Plasmodium vivax purine nucleoside phosphorylase, putative 0.3872 0.7864 1
Schistosoma mansoni fkbp-rapamycin associated protein 0.0162 0.0287 0.0287
Echinococcus multilocularis transmembrane protease serine 3 0.0074 0.0108 0.0108
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0179 0.0178
Onchocerca volvulus 0.0074 0.0108 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0162 0.0287 0.0287
Brugia malayi hypothetical protein 0.0039 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0116 0.0195 0.0195
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0055 0.007 0.007
Brugia malayi ephrin receptor 1 precursor 0.0031 0.002 0.002
Echinococcus multilocularis nAChR subunit 0.0045 0.005 0.005
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0055 0.007 0.0189
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.007
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.1399 0.2815 0.2815
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0128 0.0128
Schistosoma mansoni neuropeptide receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0125 0.0213 0.0302
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0074 0.0108 0.0108
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0179 0.0178
Schistosoma mansoni amine GPCR 0.0055 0.007 0.007
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0116 0.0195 0.0195
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.1567 0.3157 1
Echinococcus granulosus peregrin 0.0059 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0059 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0179 0.0178
Mycobacterium ulcerans purine nucleoside phosphorylase 0.4918 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.1256 0.1256
Toxoplasma gondii non-specific serine/threonine protein kinase 0.018 0.0325 0.0413
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Brugia malayi hypothetical protein 0.0055 0.007 0.007
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0108 0.0154
Schistosoma mansoni neurotransmitter gated ion channel 0.0039 0.0036 0.0036
Echinococcus granulosus g protein coupled receptor 0.0055 0.007 0.007
Brugia malayi Protein kinase domain containing protein 0.0099 0.016 0.016
Onchocerca volvulus 0.0074 0.0108 0.0108
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.007 0.007
Brugia malayi G protein-coupled receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0133 0.0228 0.0325
Loa Loa (eye worm) hypothetical protein 0.0039 0.0036 0.0051
Toxoplasma gondii hypothetical protein 0.0116 0.0194 0.0246
Schistosoma mansoni hypothetical protein 0.0032 0.0022 0.0022
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0084 0.0128 0.0128
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1453 0.2923 0.2923
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0107 0.0175 0.0523
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.014 0.0244 0.0347
Echinococcus multilocularis g protein coupled receptor 0.0055 0.007 0.007
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0179 0.0178
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Trichomonas vaginalis glutaminase, putative 0.0282 0.0532 0.0532
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.007 0.007
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0179 0.0178
Brugia malayi GnHR receptor homolog 0.0055 0.007 0.007
Echinococcus multilocularis purine nucleoside phosphorylase 0.4918 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0106 0.0106
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0074 0.0108 0.0108
Loa Loa (eye worm) glutaminase 0.0282 0.0532 0.0757
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0055 0.007 0.0189
Onchocerca volvulus 0.0039 0.0036 0.0036
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.3872 0.7864 1
Brugia malayi PAN domain containing protein 0.0038 0.0035 0.0035
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0074 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0071 0.0071
Echinococcus multilocularis voltage dependent calcium channel 0.0224 0.0415 0.0415
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.007 0.007
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0174 0.0313 0.0445
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Brugia malayi Cation transporter family protein 0.0266 0.05 0.05
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.1453 0.2923 0.3677
Entamoeba histolytica hypothetical protein 0.0055 0.007 0.0026
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.0099
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0681 0.1347 0.4249
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0179 0.0178
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0116 0.0195 0.0277
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.007 0.01
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Schistosoma mansoni nAChR subunit 0.0084 0.0128 0.0128
Brugia malayi Transient-receptor-potential like protein 0.014 0.0244 0.0244
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.4918 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.007 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0116 0.0195 0.0195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0266 0.05 0.0711
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0071 0.0071
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.007 0.007
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0157 0.0278 0.0395
Schistosoma mansoni integrin alpha-ps 0.0067 0.0095 0.0095
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.007 0.007
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0108 0.0108
Toxoplasma gondii phosphorylase family protein 0.1453 0.2923 0.3717
Echinococcus granulosus purine nucleoside phosphorylase 0.4918 1 1
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1453 0.2923 0.2923
Schistosoma mansoni hypothetical protein 0.0074 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0083 0.0127 0.018
Loa Loa (eye worm) ACC-1 protein 0.0084 0.0128 0.0183
Brugia malayi MTAP 0.1567 0.3157 0.3157
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.1453 0.2923 0.3677
Echinococcus multilocularis glycine receptor subunit beta 0.0084 0.0128 0.0128
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.007 0.007
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0035 0.005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0108 0.0108
Onchocerca volvulus 0.0084 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.0032 0.0023 0.0023
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0055 0.007 0.01
Brugia malayi Cation transporter family protein 0.0084 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.0125 0.0213 0.0213
Loa Loa (eye worm) calcium channel 0.0224 0.0415 0.059
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0108 0.0179 0.0535
Loa Loa (eye worm) hypothetical protein 0.0108 0.0179 0.0254
Onchocerca volvulus 0.0038 0.0035 0.0035
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0287 0.0543 0.0543
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0108 0.0108
Entamoeba histolytica hypothetical protein 0.0055 0.007 0.0026
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.007 0.007
Onchocerca volvulus Huntingtin homolog 0.0133 0.0228 0.0228
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0084 0.0128 0.0183
Schistosoma mansoni uridine phosphorylase 0.1453 0.2923 0.2923
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.007 0.007
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.0179 0.0178

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 0.000000000002 M mouse-1 In vivo analgesic activity of fluoro-enkephalin analog was determined against the compound at 10E-9 M/mouse; i.c.v. ChEMBL. No reference
ED50 (functional) = 0.000000000002 M mouse-1 In vivo analgesic activity of fluoro-enkephalin analog was determined against the compound at 10E-9 M/mouse; i.c.v. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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