Detailed information for compound 1384442

Basic information

Technical information
  • TDR Targets ID: 1384442
  • Name: NCGC00166373-01
  • MW: 508.568 | Formula: C30H28N4O4
  • H donors: 2 H acceptors: 3 LogP: 3.84 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1COc1ccc(cc1)NC(=O)C)C1Nc2ccccc2C(=O)N1Cc1ccccn1
  • InChi: 1S/C30H28N4O4/c1-20(35)32-23-11-13-25(14-12-23)38-19-22-17-21(10-15-28(22)37-2)29-33-27-9-4-3-8-26(27)30(36)34(29)18-24-7-5-6-16-31-24/h3-17,29,33H,18-19H2,1-2H3,(H,32,35)
  • InChiKey: KTKONMAMQPBDPW-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0117 0.0206 0.019
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Brugia malayi probable spectrin beta chain 0.0058 0.0055 0.0048
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0058 0.0055 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Onchocerca volvulus 0.0058 0.0055 0.0032
Entamoeba histolytica PH domain containing protein 0.0058 0.0055 0.0251
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Echinococcus granulosus tyrosine protein kinase csk 0.0056 0.0048 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0058 0.0055 0.0058
Echinococcus multilocularis GRB2 associated binding protein 3 0.0058 0.0055 0.0058
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Schistosoma mansoni regulator of G protein signaling 0.0636 0.1542 0.1528
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Echinococcus granulosus tyrosine protein kinase csk 0.0056 0.0048 0.005
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.0048 0.0208
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0074 0.0096 0.9056
Schistosoma mansoni zinc finger protein 0.0058 0.0055 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Trichomonas vaginalis kinesin light chain, putative 0.0058 0.0055 0.0356
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase pr2 0.0056 0.0048 0.005
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Trypanosoma cruzi PH domain containing protein, putative 0.0058 0.0055 0.1268
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0056 0.0048 0.0042
Echinococcus granulosus activin receptor type 0.0072 0.0089 0.0098
Echinococcus granulosus Rho GTPase activating protein 24 0.0058 0.0055 0.0058
Echinococcus multilocularis protein kinase 0.0056 0.0048 0.005
Echinococcus multilocularis protein KINase family member (kin 25) 0.0056 0.0048 0.005
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Echinococcus granulosus expressed protein 0.0636 0.1542 0.1837
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Brugia malayi IPT/TIG domain containing protein 0.0159 0.0315 0.0309
Echinococcus multilocularis protein kinase 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0056 0.0048 0.005
Trichomonas vaginalis protein kinase atn1, putative 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0056 0.0048 0.0042
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0159 0.0315 0.0309
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Toxoplasma gondii protein kinase domain-containing protein 0.0074 0.0096 0.9056
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0058 0.0055 0.0039
Echinococcus granulosus oxysterol binding protein 9 0.0058 0.0055 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica protein kinase , putative 0.0076 0.0101 0.055
Echinococcus multilocularis pdz domain containing protein 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0058 0.0055 0.0251
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Loa Loa (eye worm) AUR protein kinase 0.0076 0.0101 0.0094
Leishmania major protein kinase, putative 0.0076 0.0101 1
Echinococcus multilocularis roundabout 2 0.0122 0.0218 0.0253
Trypanosoma cruzi PH domain containing protein, putative 0.0058 0.0055 0.1268
Loa Loa (eye worm) hypothetical protein 0.0117 0.0206 0.0199
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0056 0.0048 0.005
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0058 0.0055 0.0032
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0056 0.0048 0.0313
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Schistosoma mansoni goodpasture antigen-binding protein 0.0058 0.0055 0.0039
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni growth factor receptor-bound protein 0.0058 0.0055 0.0039
Brugia malayi Plekhf2 protein 0.0058 0.0055 0.0048
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0056 0.0048 0.005
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0636 0.1542 0.1536
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0058 0.0055 0.0058
Echinococcus multilocularis transcription factor collier 0.0159 0.0315 0.0369
Onchocerca volvulus 0.0058 0.0055 0.0032
Schistosoma mansoni hypothetical protein 0.0058 0.0055 0.0039
Trypanosoma cruzi PH domain containing protein, putative 0.0058 0.0055 0.1268
Brugia malayi A-kinase anchor protein 10, precursor 0.0636 0.1542 0.1536
Brugia malayi Variant SH3 domain containing protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0074 0.0096 0.9056
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.3005 0.7643 0.7641
Schistosoma mansoni semaphorin 5-related 0.0364 0.0842 0.0827
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0159 0.0315 0.2046
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0096 0.0518
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica ankyrin repeat protein 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni regulator of G protein signaling 0.0636 0.1542 0.1528
Brugia malayi Probable exocyst complex component Sec5 0.0159 0.0315 0.0309
Loa Loa (eye worm) hypothetical protein 0.0364 0.0842 0.0836
Echinococcus granulosus regulator of G protein signaling 7 0.0636 0.1542 0.1837
Echinococcus multilocularis tyrosine protein kinase 0.0056 0.0048 0.005
Brugia malayi hypothetical protein 0.0636 0.1542 0.1536
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0058 0.0055 0.1268
Brugia malayi Tyrosine-protein kinase abl-1 0.0056 0.0048 0.0042
Echinococcus granulosus dynamin 1 0.0058 0.0055 0.0058
Loa Loa (eye worm) TK/ALK protein kinase 0.0292 0.0657 0.0651
Echinococcus granulosus insulin receptor 0.0056 0.0048 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Echinococcus multilocularis insulin receptor 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus multilocularis receptor type guanylyl cyclase 0.0056 0.0048 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Trichomonas vaginalis centaurin/arf, putative 0.0058 0.0055 0.0356
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.3285 0.8363 0.8362
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica hypothetical protein 0.0058 0.0055 0.0251
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0074 0.0096 0.9056
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0101 0.0652
Echinococcus multilocularis rac serine:threonine kinase 0.0074 0.0096 0.0106
Brugia malayi Immunoglobulin I-set domain containing protein 0.0122 0.0218 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0048 0.0032
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0048 0.0032
Toxoplasma gondii AtPH1 family protein 0.0058 0.0055 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Brugia malayi ephrin receptor 1 precursor 0.0056 0.0048 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Toxoplasma gondii hypothetical protein 0.0058 0.0055 0.1268
Echinococcus multilocularis activated cdc42 kinase 1 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0117 0.0206 0.0199
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Echinococcus granulosus c src tyrosine kinase 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0056 0.0048 0.005
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0173 0.0349 0.0343
Entamoeba histolytica protein kinase domain containing protein 0.0072 0.0089 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0056 0.0048 0.0042
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0117 0.0206 0.019
Entamoeba histolytica hypothetical protein 0.0159 0.0315 0.1959
Echinococcus granulosus protein tyrosine kinase 0.0056 0.0048 0.005
Brugia malayi hypothetical protein 0.0058 0.0055 0.0048
Echinococcus granulosus semaphorin 5B 0.0364 0.0842 0.0999
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Echinococcus granulosus regulator of G protein signaling 3 0.0636 0.1542 0.1837
Echinococcus multilocularis myotubularin protein 13 0.0058 0.0055 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Onchocerca volvulus 0.0058 0.0055 0.0032
Entamoeba histolytica protein kinase, putative 0.0076 0.0101 0.055
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) rho-GTPase-activating 0.0058 0.0055 0.0048
Loa Loa (eye worm) cytohesin 3 0.0058 0.0055 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0058 0.0055 0.0048
Leishmania major hypothetical protein, conserved 0.0058 0.0055 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0056 0.0048 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Echinococcus multilocularis epidermal growth factor receptor 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0364 0.0842 0.0836
Schistosoma mansoni hypothetical protein 0.0058 0.0055 0.0039
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0056 0.0048 0.0208
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Leishmania major protein kinase, putative 0.0072 0.0089 0.7789
Brugia malayi integrin-linked kinase 0.0056 0.0048 0.0042
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0056 0.0048 0.0042
Echinococcus granulosus DCC interacting protein 13 beta 0.0058 0.0055 0.0058
Loa Loa (eye worm) serine/threonine protein kinase 0.0056 0.0048 0.0042
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0056 0.0048 0.0032
Brugia malayi Furin-like cysteine rich region family protein 0.0056 0.0048 0.0042
Schistosoma mansoni dynamin 0.0058 0.0055 0.0039
Loa Loa (eye worm) Plekhf2 protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) uncoordinated protein 104 0.0058 0.0055 0.0048
Echinococcus granulosus epidermal growth factor receptor 0.0056 0.0048 0.005
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus serine/threonine protein kinase 0.0074 0.0096 0.0106
Echinococcus granulosus activated cdc42 kinase 1 0.0056 0.0048 0.005
Brugia malayi serine/threonine protein kinase 6 0.0076 0.0101 0.0094
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.0048 0.0208
Echinococcus granulosus activated cdc42 kinase 1 0.0056 0.0048 0.005
Brugia malayi protein-tyrosine kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus natriuretic peptide receptor 1 0.0056 0.0048 0.005
Toxoplasma gondii phosphatidylinositol transfer protein 0.0058 0.0055 0.1268
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) TK/RYK protein kinase 0.0056 0.0048 0.0042
Brugia malayi bone morphogenetic protein type 1 receptor 0.0056 0.0048 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Onchocerca volvulus outspread protein homolog 0.0058 0.0055 0.0032
Brugia malayi Raf kinase 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0117 0.0206 0.0199
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis integrin linked protein kinase 0.0056 0.0048 0.005
Brugia malayi SRC-1 0.0056 0.0048 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0101 0.0652
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0056 0.0048 0.0032
Plasmodium falciparum serine/threonine protein kinase, putative 0.0076 0.0101 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0056 0.0048 0.0032
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Echinococcus multilocularis plexin a4 0.1017 0.2523 0.3012
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Brugia malayi Dynamin 0.0058 0.0055 0.0048
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0074 0.0096 0.9056
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0056 0.0048 0.0208
Schistosoma mansoni protein kinase 0.0076 0.0101 0.0085
Brugia malayi Dynamin 0.0058 0.0055 0.0048
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0117 0.0206 0.0238
Entamoeba histolytica protein kinase, putative 0.0076 0.0101 0.055
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0056 0.0048 0.0042
Loa Loa (eye worm) TK/CSK protein kinase 0.0056 0.0048 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Echinococcus granulosus Pleckstrin y 0.0058 0.0055 0.0058
Onchocerca volvulus 0.0058 0.0055 0.0032
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.3005 0.7643 0.7639
Echinococcus granulosus Immunoglobulin 0.0117 0.0206 0.0238
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0056 0.0048 0.0042
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis c src tyrosine kinase 0.0056 0.0048 0.005
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0058 0.0055 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.0048 0.0208
Echinococcus multilocularis G protein coupled receptor kinase 6 0.3285 0.8363 1
Schistosoma mansoni serine/threonine-protein kinase 0.0074 0.0096 0.008
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Echinococcus granulosus exocyst complex component 2 0.0159 0.0315 0.0369
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0072 0.0089 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) hypothetical protein 0.0636 0.1542 0.1536
Schistosoma mansoni hypothetical protein 0.0058 0.0055 0.0039
Echinococcus granulosus twitchin 0.0133 0.0246 0.0287
Echinococcus granulosus fibroblast growth factor receptor 4 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0048 0.0032
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3285 0.8363 0.8362
Plasmodium vivax PH domain containing protein 0.0058 0.0055 0.1268
Schistosoma mansoni protein kinase 0.0072 0.0089 0.0073
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus granulosus Pleckstrin y 0.0058 0.0055 0.0058
Echinococcus multilocularis regulator of G protein signaling 0.0636 0.1542 0.1837
Brugia malayi regulator of G-protein signaling egl-10 0.0636 0.1542 0.1536
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus granulosus roundabout 2 0.0122 0.0218 0.0253
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Brugia malayi Immunoglobulin I-set domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Trichomonas vaginalis protein transport protein sec7, putative 0.0058 0.0055 0.0356
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi Uncoordinated protein 104 0.0058 0.0055 0.0048
Echinococcus granulosus beta 1 syntrophin 0.0058 0.0055 0.0058
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus granulosus receptor type guanylyl cyclase 0.0056 0.0048 0.005
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0056 0.0048 0.0313
Loa Loa (eye worm) SRC-1 0.0056 0.0048 0.0042
Echinococcus granulosus regulator of G protein signaling 3 0.0636 0.1542 0.1837
Schistosoma mansoni syntrophin 0.0058 0.0055 0.0039
Trichomonas vaginalis centaurin gamma, putative 0.0058 0.0055 0.0356
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Schistosoma mansoni oxysterol-binding protein 1 0.0058 0.0055 0.0039
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Loa Loa (eye worm) hypothetical protein 0.0636 0.1542 0.1536
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Echinococcus multilocularis tyrosine protein kinase Abl 0.0056 0.0048 0.005
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0208 0.0441 0.0434
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) AGC/AKT protein kinase 0.0074 0.0096 0.0089
Schistosoma mansoni hypothetical protein 0.0058 0.0055 0.0039
Echinococcus granulosus tyrosine protein kinase Lyn 0.0072 0.0089 0.0098
Echinococcus multilocularis Oxysterol binding protein 11 0.0058 0.0055 0.0058
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0058 0.0055 0.1268
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0074 0.0096 0.9056
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis FL cytokine receptor 0.0056 0.0048 0.005
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni vav2 0.0058 0.0055 0.0039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0173 0.0349 0.0343
Brugia malayi serine/threonine-protein kinase 6 0.0076 0.0101 0.0094
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis neuroglian 0.0117 0.0206 0.0238
Loa Loa (eye worm) TK/Met protein kinase 0.0056 0.0048 0.0042
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0858 0.2113 0.2107
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0072 0.0089 0.7789
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0058 0.0055 0.0356
Toxoplasma gondii aurora kinase 0.0076 0.0101 1
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Brugia malayi Tyrosine-protein kinase PR2 0.0056 0.0048 0.0042
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0056 0.0048 0.0042
Brugia malayi MAX-1A 0.0058 0.0055 0.0048
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0096 0.0518
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) oxysterol binding protein 0.0058 0.0055 0.0048
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni regulator of G protein signaling 0.0636 0.1542 0.1528
Echinococcus multilocularis Pleckstrin y 0.0058 0.0055 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Schistosoma mansoni vesicular amine transporter 0.0119 0.0212 0.0197
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus granulosus raf serine:threonine protein kinase 0.0056 0.0048 0.005
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Schistosoma mansoni fibrocystin l 0.0159 0.0315 0.03
Schistosoma mansoni protein kinase 0.0072 0.0089 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0056 0.0048 0.005
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0058 0.0055 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0096 0.0518
Schistosoma mansoni cell adhesion molecule 0.0122 0.0218 0.0202
Brugia malayi Cytohesin 3 0.0058 0.0055 0.0048
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0056 0.0048 0.0313
Loa Loa (eye worm) hypothetical protein 0.0159 0.0315 0.0309
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0074 0.0096 0.9056
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Loa Loa (eye worm) TK/DDR protein kinase 0.0056 0.0048 0.0042
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.3921 1 1
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0058 0.0055 0.0058
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0072 0.0089 0.0098
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3921 1 1
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica hypothetical protein 0.0074 0.0096 0.0518
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Entamoeba histolytica hypothetical protein, conserved 0.0058 0.0055 0.0251
Echinococcus granulosus epidermal growth factor receptor 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trypanosoma cruzi aurora B kinase, putative 0.0076 0.0101 1
Trichomonas vaginalis STE family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus integrin linked protein kinase 0.0056 0.0048 0.005
Brugia malayi PXA domain containing protein 0.0636 0.1542 0.1536
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0048 0.0042
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0074 0.0096 0.9056
Brugia malayi hypothetical protein 0.0122 0.0218 0.0212
Brugia malayi Guanylyl cyclase protein 23 0.0056 0.0048 0.0042
Brugia malayi Plexin repeat family protein 0.0858 0.2113 0.2107
Echinococcus granulosus retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Schistosoma mansoni hypothetical protein 0.0056 0.0048 0.0032
Schistosoma mansoni protein tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase shark 0.0056 0.0048 0.005
Echinococcus multilocularis Rho GTPase activating protein 24 0.0058 0.0055 0.0058
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0159 0.0315 0.2046
Trichomonas vaginalis TK family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0636 0.1542 0.1528
Giardia lamblia Aurora kinase 0.0076 0.0101 1
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0074 0.0096 0.062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0636 0.1542 0.1536
Echinococcus multilocularis semaphorin 5B 0.0364 0.0842 0.0999
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Echinococcus granulosus Regulator of G protein signaling 20 0.0636 0.1542 0.1837
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0364 0.0842 0.0836
Echinococcus multilocularis axis inhibition protein axin 0.0636 0.1542 0.1837
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus Oxysterol binding protein 11 0.0058 0.0055 0.0058
Entamoeba histolytica cell surface protease gp63, putative 0.0159 0.0315 0.1959
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Brugia malayi Receptor family ligand binding region containing protein 0.0056 0.0048 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Trypanosoma cruzi NIMA-related kinase, putative 0.0074 0.0096 0.9056
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Toxoplasma gondii hypothetical protein 0.0058 0.0055 0.1268
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0056 0.0048 0.005
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.0048 0.005
Brugia malayi Oxysterol-binding protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) PXA domain-containing protein 0.0636 0.1542 0.1536
Echinococcus multilocularis Ras associated and pleckstrin y 0.0058 0.0055 0.0058
Schistosoma mansoni ephrin receptor 0.0061 0.0061 0.0045
Echinococcus multilocularis tyrosine protein kinase Srms 0.0056 0.0048 0.005
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Schistosoma mansoni goodpasture antigen-binding protein 0.0058 0.0055 0.0039
Echinococcus granulosus tyrosine protein kinase Src64B 0.0056 0.0048 0.005
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0058 0.0055 0.0251
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0074 0.0096 0.9056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine kinase 0.0056 0.0048 0.005
Echinococcus multilocularis ephrin type A receptor 4 A 0.0056 0.0048 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0159 0.0315 0.2046
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Schistosoma mansoni regulator of G protein signaling 0.0636 0.1542 0.1528
Echinococcus multilocularis G protein coupled receptor kinase 1 0.237 0.6006 0.7179
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0058 0.0055 0.0058
Entamoeba histolytica tyrosin kinase, putative 0.0215 0.0459 0.29
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0058 0.0055 0.0356
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0364 0.0842 0.0836
Loa Loa (eye worm) hypothetical protein 0.0117 0.0206 0.0199
Echinococcus multilocularis protein tyrosine kinase 0.0056 0.0048 0.005
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0074 0.0096 0.9056
Echinococcus granulosus protein kinase 0.0056 0.0048 0.005
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0074 0.0096 0.9056
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Echinococcus granulosus pdz domain containing protein 0.0058 0.0055 0.0058
Echinococcus multilocularis hypothetical protein 0.0364 0.0842 0.0999
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.3285 0.8363 1
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Schistosoma mansoni rho gtpase activating protein 0.0058 0.0055 0.0039
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0058 0.0055 0.0058
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Brugia malayi TBC domain containing protein 0.0058 0.0055 0.0048
Loa Loa (eye worm) TK/ABL protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus calcium dependent secretion activator 1 0.0058 0.0055 0.0058
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.0048 0.005
Echinococcus multilocularis beta 1 syntrophin 0.0058 0.0055 0.0058
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Echinococcus multilocularis actin binding protein anillin 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0058 0.0055 0.0058
Loa Loa (eye worm) AUR protein kinase 0.0076 0.0101 0.0094
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0048 0.0042
Schistosoma mansoni ephrin receptor 0.0056 0.0048 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0058 0.0055 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Loa Loa (eye worm) AUR protein kinase 0.0076 0.0101 0.0094
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0076 0.0101 0.0112
Echinococcus granulosus tyrosine protein kinase HCK 0.0056 0.0048 0.005
Echinococcus multilocularis regulator of G protein signaling 3 0.0636 0.1542 0.1837
Entamoeba histolytica hypothetical protein 0.0058 0.0055 0.0251
Entamoeba histolytica hypothetical protein 0.0058 0.0055 0.0251
Entamoeba histolytica protein kinase domain containing protein 0.0215 0.0459 0.29
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni centaurin alpha 0.0058 0.0055 0.0039
Plasmodium falciparum oxysterol-binding protein, putative 0.0058 0.0055 0.1268
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0058 0.0055 0.0048
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Loa Loa (eye worm) hypothetical protein 0.0159 0.0315 0.0309
Echinococcus granulosus axis inhibition protein axin 0.0636 0.1542 0.1837
Echinococcus granulosus G protein coupled receptor kinase 1 0.237 0.6006 0.7179
Brugia malayi Pleckstrin Homology Domain 0.0058 0.0055 0.0048
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Schistosoma mansoni hypothetical protein 0.0159 0.0315 0.03
Echinococcus multilocularis Regulator of G protein signaling 20 0.0636 0.1542 0.1837
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK/ROR protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0058 0.0055 0.0251
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0056 0.0048 0.005
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0058 0.0055 0.0251
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0058 0.0055 0.0058
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0076 0.0101 1
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) protein kinase domain-containing protein 0.0056 0.0048 0.0042
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0076 0.0101 0.055
Trypanosoma brucei protein kinase, putative 0.0072 0.0089 0.7789
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Entamoeba histolytica cysteine surface protein, putative 0.0056 0.0048 0.0208
Echinococcus granulosus transcription factor collier 0.0159 0.0315 0.0369
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Brugia malayi Sema domain containing protein 0.0364 0.0842 0.0836
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0074 0.0096 0.9056
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0058 0.0055 0.0251
Entamoeba histolytica receptor protein kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0056 0.0048 0.0042
Echinococcus granulosus tyrosine protein kinase Src42A 0.0056 0.0048 0.005
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Schistosoma mansoni zinc finger protein 0.0058 0.0055 0.0039
Brugia malayi SH2 domain containing protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0122 0.0218 0.0212
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0058 0.0055 0.0039
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0061 0.0061 0.0065
Echinococcus granulosus pleckstrin y domain containing family A 0.0058 0.0055 0.0058
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0058 0.0055 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Toxoplasma gondii Oxysterol-binding protein 0.0058 0.0055 0.1268
Loa Loa (eye worm) hypothetical protein 0.0122 0.0218 0.0212
Echinococcus granulosus tyrosine protein kinase csk 0.0056 0.0048 0.005
Trichomonas vaginalis centaurin beta, putative 0.0058 0.0055 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni dynamin 0.0058 0.0055 0.0039
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0056 0.0048 0.005
Echinococcus granulosus GRB2 associated binding protein 3 0.0058 0.0055 0.0058
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Brugia malayi hypothetical protein 0.0636 0.1542 0.1536
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Echinococcus multilocularis tyrosine protein kinase Blk 0.0056 0.0048 0.005
Echinococcus granulosus axis inhibition protein axin 0.0636 0.1542 0.1837
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0636 0.1542 0.1528
Echinococcus granulosus ephrin type A receptor 4 A 0.0056 0.0048 0.005
Schistosoma mansoni hypothetical protein 0.0159 0.0315 0.03
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0076 0.0101 0.055
Schistosoma mansoni plexin 0.0858 0.2113 0.21
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Trypanosoma cruzi PH domain containing protein, putative 0.0058 0.0055 0.1268
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0159 0.0315 0.0309
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Entamoeba histolytica hypothetical protein 0.0058 0.0055 0.0251
Trichomonas vaginalis protein tyrosine kinase, putative 0.0056 0.0048 0.0313
Echinococcus granulosus tyrosine protein kinase Blk 0.0056 0.0048 0.005
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0055 0.1268
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.0048 0.005
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.3285 0.8363 0.8362
Onchocerca volvulus 0.0058 0.0055 0.0032
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0056 0.0048 0.0042
Brugia malayi PXA domain containing protein 0.0636 0.1542 0.1536
Trichomonas vaginalis centaurin/arf, putative 0.0058 0.0055 0.0356
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0056 0.0048 0.005
Leishmania major protein kinase, putative 0.0074 0.0096 0.9056
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Brugia malayi plexin A 0.1017 0.2523 0.2518
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0074 0.0096 0.9056
Entamoeba histolytica hypothetical protein 0.0159 0.0315 0.1959
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Echinococcus granulosus defective proboscis extension response 0.0117 0.0206 0.0238
Echinococcus multilocularis Immunoglobulin 0.0117 0.0206 0.0238
Onchocerca volvulus Putative zinc finger protein 0.0058 0.0055 0.0032
Schistosoma mansoni axis inhibition protein axin 0.0636 0.1542 0.1528
Brugia malayi C-terminal src kinase protein 1 0.0056 0.0048 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Loa Loa (eye worm) syntrophin-1 0.0058 0.0055 0.0048
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Loa Loa (eye worm) TK/INSR protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0074 0.0096 0.062
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Brugia malayi hypothetical protein 0.0364 0.0842 0.0836
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Brugia malayi hypothetical protein 0.0364 0.0842 0.0836
Echinococcus granulosus retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Trypanosoma cruzi hypothetical protein 0.0058 0.0055 0.1268
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0058 0.0055 0.0048
Schistosoma mansoni tyrosine protein kinase 0.0056 0.0048 0.0032
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0058 0.0055 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0636 0.1542 1
Entamoeba histolytica protein kinase domain containing protein 0.0076 0.0101 0.055
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus tyrosine kinase 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0074 0.0096 0.9056
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0159 0.0315 0.2046
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis raf serine:threonine protein kinase 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus neuroglian 0.0117 0.0206 0.0238
Echinococcus multilocularis transfer RNA-Thr 0.0056 0.0048 0.005
Schistosoma mansoni axis inhibition protein axin 0.0636 0.1542 0.1528
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus granulosus oxysterol binding protein 3 0.0058 0.0055 0.0058
Echinococcus multilocularis tyrosine kinase 0.0056 0.0048 0.005
Echinococcus granulosus Pleckstrin y 0.0058 0.0055 0.0058
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0056 0.0048 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0096 0.0518
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus multilocularis tyrosine protein kinase HCK 0.0056 0.0048 0.005
Trypanosoma brucei rac serine-threonine kinase, putative 0.0074 0.0096 0.9056
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) TK/EGFR protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Brugia malayi Regulator of G protein signaling domain containing protein 0.0636 0.1542 0.1536
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Echinococcus multilocularis activin receptor type 0.0072 0.0089 0.0098
Entamoeba histolytica hypothetical protein, conserved 0.0056 0.0048 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.1542 1
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0058 0.0055 0.0058
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0056 0.0048 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis protein transport protein sec7, putative 0.0058 0.0055 0.0356
Echinococcus multilocularis tyrosine kinase 0.0056 0.0048 0.005
Entamoeba histolytica hypothetical protein 0.0058 0.0055 0.0251
Schistosoma mansoni hypothetical protein 0.0364 0.0842 0.0827
Brugia malayi regulator of G-protein signaling rgs-7 0.0636 0.1542 0.1536
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0636 0.1542 0.1536
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0058 0.0055 0.0039
Brugia malayi Variant SH3 domain containing protein 0.0058 0.0055 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Schistosoma mansoni oxysterol-binding protein 1 0.0058 0.0055 0.0039
Trichomonas vaginalis alpha chimerin, putative 0.0058 0.0055 0.0356
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) PH domain-containing protein 0.0058 0.0055 0.0048
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Echinococcus granulosus tyrosine protein kinase ABL1 0.0056 0.0048 0.005
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Entamoeba histolytica hypothetical protein 0.0159 0.0315 0.1959
Trypanosoma cruzi NIMA-related kinase, putative 0.0074 0.0096 0.9056
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica hypothetical protein 0.0636 0.1542 1
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0101 0.0652
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Brugia malayi hypothetical protein 0.0056 0.0048 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.1542 1
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0058 0.0055 0.0048
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0058 0.0055 0.0032
Echinococcus granulosus beta-adrenergic receptor kinase 0.3005 0.7643 0.9138
Entamoeba histolytica p21-activated kinase 0.0074 0.0096 0.0518
Onchocerca volvulus 0.0058 0.0055 0.0032
Schistosoma mansoni hypothetical protein 0.0058 0.0055 0.0039
Leishmania major hypothetical protein, conserved 0.0058 0.0055 0.1268
Loa Loa (eye worm) sema domain-containing protein 0.0364 0.0842 0.0836
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Echinococcus multilocularis tyrosine protein kinase shark 0.0056 0.0048 0.005
Plasmodium falciparum protein kinase, putative 0.0072 0.0089 0.7789
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.1542 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.0218 0.0212
Brugia malayi serine/threonine kinase 12 0.0076 0.0101 0.0094
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis pleckstrin y domain containing family A 0.0058 0.0055 0.0058
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.0048 0.0208
Echinococcus multilocularis Pleckstrin y 0.0058 0.0055 0.0058
Schistosoma mansoni protein kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0056 0.0048 0.005
Schistosoma mansoni serine/threonine-protein kinase 0.0074 0.0096 0.008
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni serine/threonine RGC 0.0056 0.0048 0.0032
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0058 0.0055 0.0058
Onchocerca volvulus 0.0858 0.2113 1
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.1542 1
Brugia malayi Cadps2 protein 0.0058 0.0055 0.0048
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Echinococcus multilocularis tyrosine protein kinase pr2 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Trichomonas vaginalis hypothetical protein 0.0058 0.0055 0.0356
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0058 0.0055 0.0356
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0017 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Brugia malayi Protein kinase domain containing protein 0.0292 0.0657 0.0651
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase Srms 0.0056 0.0048 0.005
Trypanosoma cruzi Protein kinase B 0.0074 0.0096 0.9056
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0056 0.0048 0.0042
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi Syntrophin-1 0.0058 0.0055 0.0048
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Loa Loa (eye worm) hypothetical protein 0.0364 0.0842 0.0836
Echinococcus multilocularis axis inhibition protein axin 0.0636 0.1542 0.1837
Echinococcus multilocularis regulator of G protein signaling 7 0.0636 0.1542 0.1837
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0056 0.0048 0.0208
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Loa Loa (eye worm) hypothetical protein 0.0117 0.0206 0.0199
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus multilocularis exocyst complex component 2 0.0159 0.0315 0.0369
Plasmodium falciparum PH domain-containing protein, putative 0.0058 0.0055 0.1268
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Leishmania major protein kinase, putative 0.0074 0.0096 0.9056
Loa Loa (eye worm) plexin A 0.1017 0.2523 0.2518
Loa Loa (eye worm) TK/EPH protein kinase 0.0056 0.0048 0.0042
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0056 0.0048 0.0042
Entamoeba histolytica PH domain containing protein 0.0058 0.0055 0.0251
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0076 0.0101 0.055
Trypanosoma brucei protein kinase, putative 0.0074 0.0096 0.9056
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0058 0.0055 0.0058
Echinococcus granulosus tyrosine protein kinase 0.0056 0.0048 0.005
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0056 0.0048 0.005
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0058 0.0055 0.0356
Echinococcus multilocularis oxysterol binding protein 9 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0048 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0636 0.1542 0.1837
Brugia malayi Protein kinase domain containing protein 0.0074 0.0096 0.0089
Loa Loa (eye worm) RGS-3 protein 0.0636 0.1542 0.1536
Brugia malayi PH domain containing protein 0.0058 0.0055 0.0048
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0061 0.0061 0.0065
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0096 0.0518
Echinococcus granulosus tyrosine kinase 0.0056 0.0048 0.005
Schistosoma mansoni hypothetical protein 0.0364 0.0842 0.0827
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0056 0.0048 0.0032
Echinococcus multilocularis beta adrenergic receptor kinase 0.3005 0.7643 0.9138
Schistosoma mansoni plexin 0.0494 0.1176 0.1161
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0074 0.0096 0.9056
Echinococcus multilocularis DCC interacting protein 13 beta 0.0058 0.0055 0.0058
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus granulosus regulator of G protein signaling 7 0.0636 0.1542 0.1837
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0494 0.1176 0.117
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0636 0.1542 0.1837
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Loa Loa (eye worm) sema domain-containing protein 0.0364 0.0842 0.0836
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Trypanosoma brucei aurora B kinase 0.0076 0.0101 1
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.1542 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Leishmania major serine/threonine-protein kinase a, putative 0.0074 0.0096 0.9056
Onchocerca volvulus 0.0364 0.0842 0.3844
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0636 0.1542 0.1528
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0072 0.0089 0.7789
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0056 0.0048 0.005
Echinococcus multilocularis Pleckstrin y 0.0058 0.0055 0.0058
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0058 0.0055 0.1268
Schistosoma mansoni serine/threonine protein kinase 0.3005 0.7643 0.7639
Entamoeba histolytica PH domain containing protein 0.0058 0.0055 0.0251
Echinococcus granulosus plexin a4 0.1017 0.2523 0.3012
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0058 0.0055 0.0058
Loa Loa (eye worm) hypothetical protein 0.0636 0.1542 0.1536
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0159 0.0315 0.2046
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0058 0.0055 0.0039
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0074 0.0096 0.9056
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0117 0.0206 0.0238
Brugia malayi Fibronectin type III domain containing protein 0.0122 0.0218 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0159 0.0315 0.2046
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0072 0.0089 0.7789
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0017 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Loa Loa (eye worm) hypothetical protein 0.0117 0.0206 0.0199
Echinococcus granulosus cytohesin 1 0.0058 0.0055 0.0058
Entamoeba histolytica receptor protein kinase, putative 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0058 0.0055 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis calcium dependent secretion activator 1 0.0058 0.0055 0.0058
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Echinococcus multilocularis expressed protein 0.0636 0.1542 0.1837
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042
Brugia malayi Sema domain containing protein 0.0364 0.0842 0.0836
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0056 0.0048 0.0032
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0101 0.0085
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0056 0.0048 0.005
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0058 0.0055 0.1268
Loa Loa (eye worm) TK/ACK protein kinase 0.0056 0.0048 0.0042
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0074 0.0096 0.9056
Schistosoma mansoni hypothetical protein 0.0494 0.1176 0.1161
Onchocerca volvulus Protein melted homolog 0.0058 0.0055 0.0032
Onchocerca volvulus 0.0058 0.0055 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.1542 1
Entamoeba histolytica ARF GTPase activating protein, putative 0.0058 0.0055 0.0251
Echinococcus granulosus myotubularin protein 13 0.0058 0.0055 0.0058
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0048 0.0042
Schistosoma mansoni nephrin 0.0122 0.0218 0.0202
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0101 0.0652
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0017 0.0012
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0058 0.0055 0.0251
Brugia malayi hypothetical protein 0.0056 0.0048 0.0042
Schistosoma mansoni z-protein (S1r protein) 0.0636 0.1542 0.1528
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0056 0.0048 0.005
Entamoeba histolytica hypothetical protein 0.0636 0.1542 1
Schistosoma mansoni tyrosine kinase 0.0056 0.0048 0.0032
Echinococcus granulosus semaphorin 1A 0.0364 0.0842 0.0999
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0048 0.0208
Echinococcus multilocularis heat shock protein 70 0.0056 0.0048 0.005
Plasmodium falciparum calcium-dependent protein kinase 7 0.0074 0.0096 0.9056
Trichomonas vaginalis AGC family protein kinase 0.0074 0.0096 0.062
Leishmania major folate/biopterin transporter, putative 0.0074 0.0096 0.9056
Echinococcus multilocularis epidermal growth factor receptor 0.0056 0.0048 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0056 0.0048 0.005
Echinococcus multilocularis regulator of G protein signaling 3 0.0636 0.1542 0.1837
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0056 0.0048 0.005
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0056 0.0048 0.005
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Entamoeba histolytica ankyrin repeat protein 0.0056 0.0048 0.0208
Entamoeba histolytica hypothetical protein 0.0074 0.0096 0.0518
Loa Loa (eye worm) hypothetical protein 0.0364 0.0842 0.0836
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0055 0.1268
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0096 0.0518
Echinococcus multilocularis regulator of G protein signaling 7 0.0636 0.1542 0.1837
Schistosoma mansoni protein kinase 0.0072 0.0089 0.0073
Entamoeba histolytica hypothetical protein 0.0159 0.0315 0.1959
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Brugia malayi SH2 domain containing protein 0.0056 0.0048 0.0042
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0058 0.0055 0.0251
Schistosoma mansoni myotubularin-related protein 0.0058 0.0055 0.0039
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0074 0.0096 0.9056
Echinococcus multilocularis natriuretic peptide receptor 1 0.0056 0.0048 0.005
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0056 0.0048 0.005
Trichomonas vaginalis centaurin alpha, putative 0.0058 0.0055 0.0356
Trypanosoma brucei PH domain containing protein, putative 0.0058 0.0055 0.1268
Brugia malayi Regulator of G protein signaling domain containing protein 0.0636 0.1542 0.1536
Echinococcus granulosus aurora kinase A 0.0076 0.0101 0.0112
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.0048 0.005
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Echinococcus granulosus kinase suppressor of Ras 1 0.0056 0.0048 0.005
Loa Loa (eye worm) TK protein kinase 0.0056 0.0048 0.0042
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0056 0.0048 0.005
Echinococcus multilocularis oxysterol binding protein 1 0.0058 0.0055 0.0058
Entamoeba histolytica protein kinase, putative 0.0074 0.0096 0.0518
Echinococcus granulosus oxysterol binding protein 1 0.0058 0.0055 0.0058
Echinococcus multilocularis aurora kinase A 0.0076 0.0101 0.0112
Entamoeba histolytica protein kinase, putative 0.0056 0.0048 0.0208
Schistosoma mansoni regulator of G protein signaling 0.0636 0.1542 0.1528
Brugia malayi DNA-binding protein LAG-1 0.0159 0.0315 0.0309
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0076 0.0101 0.0112
Echinococcus multilocularis oxysterol binding protein 3 0.0058 0.0055 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0072 0.0089 0.7789
Echinococcus multilocularis dynamin 1 0.0058 0.0055 0.0058
Entamoeba histolytica hypothetical protein 0.0636 0.1542 1
Brugia malayi hypothetical protein 0.0056 0.0048 0.0042
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0056 0.0048 0.005
Echinococcus multilocularis cytohesin 1 0.0058 0.0055 0.0058
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.0048 0.0042
Entamoeba histolytica hypothetical protein 0.0056 0.0048 0.0208
Schistosoma mansoni hypothetical protein 0.0043 0.0017 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0048 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0055 0.0356
Loa Loa (eye worm) hypothetical protein 0.0636 0.1542 0.1536
Loa Loa (eye worm) TK/FAK protein kinase 0.0056 0.0048 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0056 0.0048 0.0313
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0058 0.0055 0.1268
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0048
Brugia malayi Oxysterol binding protein 0.0058 0.0055 0.0048
Echinococcus multilocularis kinase suppressor of Ras 1 0.0056 0.0048 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0056 0.0048 0.0042
Echinococcus multilocularis Immunoglobulin 0.0117 0.0206 0.0238
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0056 0.0048 0.005
Brugia malayi hypothetical protein 0.0043 0.0017 0.001
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0058 0.0055 0.0356
Brugia malayi Protein kinase domain containing protein 0.0056 0.0048 0.0042

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: Secondary Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor: HTRF Activity Detection. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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