Detailed information for compound 1389532

Basic information

Technical information
  • TDR Targets ID: 1389532
  • Name: 3-[[2-(trifluoromethyl)phenyl]sulfonylamino]p ropanoic acid
  • MW: 297.251 | Formula: C10H10F3NO4S
  • H donors: 2 H acceptors: 4 LogP: 1.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCNS(=O)(=O)c1ccccc1C(F)(F)F
  • InChi: 1S/C10H10F3NO4S/c11-10(12,13)7-3-1-2-4-8(7)19(17,18)14-6-5-9(15)16/h1-4,14H,5-6H2,(H,15,16)
  • InChiKey: IHCFNIXTIKJHGG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[[2-(trifluoromethyl)phenyl]sulfonylamino]propionic acid
  • UNM000000687201
  • MLS000774674
  • SMR000372441
  • EU-0049014
  • ChemDiv3_005202

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus receptor type guanylyl cyclase 0.0065 0.004 0.0043
Echinococcus granulosus oxysterol binding protein 9 0.0091 0.0084 0.0095
Echinococcus multilocularis protein kinase 0.0065 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Echinococcus multilocularis tyrosine protein kinase csk 0.0065 0.004 0.0043
Echinococcus multilocularis GRB2 associated binding protein 3 0.0091 0.0084 0.0095
Echinococcus multilocularis pdz domain containing protein 0.0091 0.0084 0.0095
Brugia malayi TBC domain containing protein 0.0091 0.0084 0.008
Echinococcus multilocularis aurora kinase A 0.0091 0.0083 0.0094
Schistosoma mansoni oxysterol-binding protein 1 0.0091 0.0084 0.0073
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Loa Loa (eye worm) hypothetical protein 0.0132 0.0151 0.0146
Echinococcus granulosus epidermal growth factor receptor 0.0065 0.004 0.0043
Brugia malayi Cadps2 protein 0.0091 0.0084 0.008
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0116 0.0125 0.0795
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Toxoplasma gondii phosphatidylinositol transfer protein 0.0091 0.0084 0.5229
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0091 0.0084 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0116 0.0125 1
Schistosoma mansoni goodpasture antigen-binding protein 0.0091 0.0084 0.0073
Echinococcus multilocularis c src tyrosine kinase 0.0065 0.004 0.0043
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0065 0.004 0.0043
Echinococcus multilocularis expressed protein 0.0996 0.1567 0.1868
Loa Loa (eye worm) AUR protein kinase 0.0091 0.0083 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Loa Loa (eye worm) hypothetical protein 0.0996 0.1567 0.1563
Schistosoma mansoni regulator of G protein signaling 0.0996 0.1567 0.1557
Trypanosoma cruzi aurora B kinase, putative 0.0091 0.0083 0.5095
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0091 0.0084 0.0288
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0065 0.004 0.0043
Echinococcus multilocularis kinase suppressor of Ras 1 0.0065 0.004 0.0043
Entamoeba histolytica hypothetical protein 0.0186 0.024 0.1309
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0116 0.0125 1
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Brugia malayi hypothetical protein 0.0426 0.0632 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0996 0.1567 1
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0091 0.0084 0.0095
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0091 0.0084 0.008
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0065 0.004 0.0043
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0091 0.0084 0.0286
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0116 0.0125 1
Entamoeba histolytica PH domain containing protein 0.0091 0.0084 0.0288
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Echinococcus multilocularis hypothetical protein 0.0426 0.0632 0.075
Entamoeba histolytica hypothetical protein 0.0091 0.0084 0.0288
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0116 0.0125 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0996 0.1567 0.1563
Loa Loa (eye worm) Plekhf2 protein 0.0091 0.0084 0.008
Schistosoma mansoni dynamin 0.0091 0.0084 0.0073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Schistosoma mansoni serine/threonine RGC 0.0065 0.004 0.0029
Echinococcus multilocularis myotubularin protein 13 0.0091 0.0084 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus multilocularis epidermal growth factor receptor 0.0065 0.004 0.0043
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0065 0.004 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus cytohesin 1 0.0091 0.0084 0.0095
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0065 0.004 0.0029
Echinococcus granulosus ephrin type A receptor 4 A 0.0065 0.004 0.0043
Brugia malayi Sema domain containing protein 0.0426 0.0632 0.0628
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Loa Loa (eye worm) hypothetical protein 0.0426 0.0632 0.0628
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus calcium dependent secretion activator 1 0.0091 0.0084 0.0095
Trichomonas vaginalis centaurin gamma, putative 0.0091 0.0084 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Brugia malayi probable spectrin beta chain 0.0091 0.0084 0.008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Schistosoma mansoni hypothetical protein 0.0186 0.024 0.0229
Brugia malayi C-terminal src kinase protein 1 0.0065 0.004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0132 0.0151 0.0146
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0132 0.0151 0.014
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Schistosoma mansoni rho gtpase activating protein 0.0091 0.0084 0.0073
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus multilocularis tyrosine protein kinase csk 0.0065 0.004 0.0043
Echinococcus multilocularis regulator of G protein signaling 7 0.0996 0.1567 0.1868
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus granulosus tyrosine protein kinase Src64B 0.0065 0.004 0.0043
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Schistosoma mansoni ephrin receptor 0.0065 0.004 0.0029
Echinococcus granulosus axis inhibition protein axin 0.0996 0.1567 0.1868
Schistosoma mansoni tyrosine protein kinase 0.0065 0.004 0.0029
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0132 0.0151 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus defective proboscis extension response 0.0132 0.0151 0.0175
Brugia malayi MAX-1A 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0091 0.0084 0.0539
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0065 0.004 0.0036
Schistosoma mansoni vav2 0.0091 0.0084 0.0073
Brugia malayi Probable exocyst complex component Sec5 0.0186 0.024 0.0236
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Loa Loa (eye worm) TK/Met protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis tyrosine protein kinase shark 0.0065 0.004 0.0043
Trichomonas vaginalis kinesin light chain, putative 0.0091 0.0084 0.0539
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0091 0.0084 0.0095
Entamoeba histolytica p21-activated kinase 0.0116 0.0125 0.0551
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Plasmodium falciparum calcium-dependent protein kinase 7 0.0116 0.0125 1
Entamoeba histolytica hypothetical protein 0.0091 0.0084 0.0288
Echinococcus multilocularis tyrosine protein kinase 0.0065 0.004 0.0043
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0065 0.004 0.0036
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0065 0.004 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.1004 0.1579 0.1576
Echinococcus multilocularis raf serine:threonine protein kinase 0.0065 0.004 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Loa Loa (eye worm) hypothetical protein 0.0226 0.0304 0.03
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Echinococcus multilocularis receptor type guanylyl cyclase 0.0065 0.004 0.0043
Loa Loa (eye worm) TK/ACK protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis transcription factor collier 0.0186 0.024 0.0282
Schistosoma mansoni serine/threonine-protein kinase 0.0116 0.0125 0.0114
Schistosoma mansoni hypothetical protein 0.0091 0.0084 0.0073
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0091 0.0084 0.0539
Echinococcus multilocularis DCC interacting protein 13 beta 0.0091 0.0084 0.0095
Entamoeba histolytica PH domain containing protein kinase, putative 0.0116 0.0125 0.0551
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0132 0.0151 0.0146
Entamoeba histolytica hypothetical protein 0.0091 0.0084 0.0288
Loa Loa (eye worm) uncoordinated protein 104 0.0091 0.0084 0.008
Echinococcus multilocularis protein kinase 0.0065 0.004 0.0043
Echinococcus granulosus tyrosine protein kinase csk 0.0065 0.004 0.0043
Echinococcus granulosus protein kinase 0.0065 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0996 0.1567 0.1563
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Loa Loa (eye worm) TK/ROR protein kinase 0.0065 0.004 0.0036
Onchocerca volvulus Putative zinc finger protein 0.0091 0.0084 0.0286
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0065 0.004 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0083 0.0072
Schistosoma mansoni ephrin receptor 0.007 0.0049 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Loa Loa (eye worm) cytohesin 3 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0186 0.024 0.0236
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0065 0.004 0.0043
Echinococcus multilocularis beta adrenergic receptor kinase 0.4708 0.765 0.9141
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0091 0.0084 0.008
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trichomonas vaginalis centaurin beta, putative 0.0091 0.0084 0.0539
Entamoeba histolytica PH domain containing protein 0.0091 0.0084 0.0288
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Loa Loa (eye worm) AGC/AKT protein kinase 0.0116 0.0125 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Schistosoma mansoni hypothetical protein 0.0091 0.0084 0.0073
Plasmodium falciparum PH domain-containing protein, putative 0.0091 0.0084 0.5229
Brugia malayi bone morphogenetic protein type 1 receptor 0.0065 0.004 0.0036
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0065 0.004 0.0029
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Onchocerca volvulus 0.0091 0.0084 0.0286
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Schistosoma mansoni vesicular amine transporter 0.0135 0.0155 0.0145
Echinococcus granulosus tyrosine protein kinase shark 0.0065 0.004 0.0043
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0089 0.0081 0.0091
Schistosoma mansoni nephrin 0.0137 0.0159 0.0149
Loa Loa (eye worm) hypothetical protein 0.0996 0.1567 0.1563
Toxoplasma gondii hypothetical protein 0.0091 0.0084 0.5229
Onchocerca volvulus 0.0091 0.0084 0.0286
Brugia malayi PXA domain containing protein 0.0996 0.1567 0.1563
Brugia malayi hypothetical protein 0.0137 0.0159 0.0155
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Giardia lamblia Aurora kinase 0.0091 0.0083 1
Loa Loa (eye worm) AUR protein kinase 0.0091 0.0083 0.0079
Brugia malayi Receptor family ligand binding region containing protein 0.0065 0.004 0.0036
Brugia malayi Variant SH3 domain containing protein 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus multilocularis beta 1 syntrophin 0.0091 0.0084 0.0095
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Entamoeba histolytica hypothetical protein 0.0996 0.1567 1
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0091 0.0084 0.0095
Loa Loa (eye worm) protein kinase domain-containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0065 0.004 0.0043
Echinococcus multilocularis actin binding protein anillin 0.0091 0.0084 0.0095
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus roundabout 2 0.0137 0.0159 0.0185
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Schistosoma mansoni hypothetical protein 0.0065 0.004 0.0029
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Entamoeba histolytica hypothetical protein 0.0996 0.1567 1
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0116 0.0125 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0065 0.004 0.0043
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0091 0.0084 0.5229
Echinococcus multilocularis Immunoglobulin 0.0132 0.0151 0.0175
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Entamoeba histolytica protein kinase, putative 0.0091 0.0083 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Echinococcus granulosus tyrosine protein kinase ABL1 0.0065 0.004 0.0043
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0065 0.004 0.0043
Echinococcus multilocularis regulator of G protein signaling 3 0.0996 0.1567 0.1868
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0065 0.004 0.0029
Echinococcus granulosus axis inhibition protein axin 0.0996 0.1567 0.1868
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0084 0.5229
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Brugia malayi Oxysterol-binding protein 0.0091 0.0084 0.008
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0186 0.024 0.1533
Brugia malayi Regulator of G protein signaling domain containing protein 0.0996 0.1567 0.1563
Brugia malayi Regulator of G protein signaling domain containing protein 0.0996 0.1567 0.1563
Echinococcus multilocularis tyrosine kinase 0.0065 0.004 0.0043
Entamoeba histolytica PH domain containing protein kinase, putative 0.0116 0.0125 0.0551
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0065 0.004 0.0043
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0186 0.024 0.0236
Echinococcus granulosus tyrosine protein kinase Srms 0.0065 0.004 0.0043
Schistosoma mansoni hypothetical protein 0.0426 0.0632 0.0622
Echinococcus multilocularis FL cytokine receptor 0.0065 0.004 0.0043
Echinococcus multilocularis exocyst complex component 2 0.0186 0.024 0.0282
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Onchocerca volvulus 0.0091 0.0084 0.0286
Echinococcus granulosus tyrosine protein kinase HCK 0.0065 0.004 0.0043
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Schistosoma mansoni protein kinase 0.0089 0.0081 0.007
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus exocyst complex component 2 0.0186 0.024 0.0282
Echinococcus multilocularis tyrosine protein kinase Srms 0.0065 0.004 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus GRB2 associated binding protein 3 0.0091 0.0084 0.0095
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0065 0.004 0.0043
Loa Loa (eye worm) RGS-3 protein 0.0996 0.1567 0.1563
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0132 0.0151 0.0175
Entamoeba histolytica hypothetical protein 0.0996 0.1567 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Echinococcus granulosus oxysterol binding protein 1 0.0091 0.0084 0.0095
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0065 0.004 0.0029
Echinococcus multilocularis tyrosine protein kinase csk 0.0065 0.004 0.0043
Echinococcus multilocularis insulin receptor 0.0065 0.004 0.0043
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0065 0.004 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Schistosoma mansoni oxysterol-binding protein 1 0.0091 0.0084 0.0073
Echinococcus granulosus c src tyrosine kinase 0.0065 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0426 0.0632 0.0628
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0116 0.0125 1
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis TK family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.007 0.0049 0.0053
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) oxysterol binding protein 0.0091 0.0084 0.008
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.5146 0.8368 0.8367
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0065 0.004 0.0043
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0065 0.004 0.0043
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0065 0.004 0.0043
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0091 0.0084 0.0286
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0089 0.0081 0.4771
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Brugia malayi protein-tyrosine kinase 0.0065 0.004 0.0036
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0091 0.0084 0.0095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0159 0.0155
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.4708 0.765 0.7649
Echinococcus granulosus tyrosine protein kinase Src42A 0.0065 0.004 0.0043
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0996 0.1567 0.1557
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Onchocerca volvulus 0.0426 0.0632 0.3845
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0091 0.0084 0.008
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Brugia malayi Oxysterol binding protein 0.0091 0.0084 0.008
Brugia malayi Dynamin 0.0091 0.0084 0.008
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0091 0.0084 0.0073
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0091 0.0084 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi serine/threonine kinase 12 0.0091 0.0083 0.0079
Brugia malayi Guanylyl cyclase protein 23 0.0065 0.004 0.0036
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Leishmania major hypothetical protein, conserved 0.0091 0.0084 0.5229
Schistosoma mansoni growth factor receptor-bound protein 0.0091 0.0084 0.0073
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trypanosoma brucei protein kinase, putative 0.0089 0.0081 0.4771
Schistosoma mansoni centaurin alpha 0.0091 0.0084 0.0073
Loa Loa (eye worm) hypothetical protein 0.0426 0.0632 0.0628
Loa Loa (eye worm) sema domain-containing protein 0.0426 0.0632 0.0628
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0065 0.004 0.0043
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0091 0.0084 0.0073
Echinococcus granulosus natriuretic peptide receptor 1 0.0065 0.004 0.0043
Loa Loa (eye worm) rho-GTPase-activating 0.0091 0.0084 0.008
Leishmania major protein kinase, putative 0.0116 0.0125 1
Loa Loa (eye worm) syntrophin-1 0.0091 0.0084 0.008
Onchocerca volvulus Protein melted homolog 0.0091 0.0084 0.0286
Leishmania major serine/threonine-protein kinase a, putative 0.0116 0.0125 1
Brugia malayi PXA domain containing protein 0.0996 0.1567 0.1563
Entamoeba histolytica hypothetical protein, conserved 0.0091 0.0084 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0996 0.1567 1
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0091 0.0084 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Schistosoma mansoni regulator of G protein signaling 0.0996 0.1567 0.1557
Echinococcus multilocularis G protein coupled receptor kinase 6 0.5146 0.8368 1
Entamoeba histolytica hypothetical protein 0.0116 0.0125 0.0551
Echinococcus multilocularis axis inhibition protein axin 0.0996 0.1567 0.1868
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0091 0.0084 0.5229
Loa Loa (eye worm) TK/ABL protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Echinococcus granulosus dynamin 1 0.0091 0.0084 0.0095
Loa Loa (eye worm) PH domain-containing protein 0.0091 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus granulosus serine/threonine protein kinase 0.0116 0.0125 0.0143
Echinococcus multilocularis tyrosine protein kinase pr2 0.0065 0.004 0.0043
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Entamoeba histolytica hypothetical protein 0.0091 0.0084 0.0288
Entamoeba histolytica protein kinase domain containing protein 0.0251 0.0346 0.2002
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi hypothetical protein 0.0426 0.0632 0.0628
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0065 0.004 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0996 0.1567 0.1563
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Entamoeba histolytica hypothetical protein 0.0091 0.0084 0.0288
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0091 0.0084 0.5229
Trichomonas vaginalis AGC family protein kinase 0.0065 0.004 0.0258
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0091 0.0083 0.0281
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0186 0.024 0.1533
Echinococcus granulosus Pleckstrin y 0.0091 0.0084 0.0095
Loa Loa (eye worm) TK/EPH protein kinase 0.0065 0.004 0.0036
Trypanosoma cruzi NIMA-related kinase, putative 0.0116 0.0125 1
Echinococcus multilocularis neuroglian 0.0132 0.0151 0.0175
Schistosoma mansoni axis inhibition protein axin 0.0996 0.1567 0.1557
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0186 0.024 0.1533
Echinococcus granulosus insulin growth factor 1 receptor beta 0.007 0.0049 0.0053
Loa Loa (eye worm) hypothetical protein 0.0186 0.024 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0116 0.0125 0.0795
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Echinococcus multilocularis ephrin type A receptor 4 A 0.0065 0.004 0.0043
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0065 0.004 0.0029
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0065 0.004 0.0043
Echinococcus granulosus transcription factor collier 0.0186 0.024 0.0282
Echinococcus multilocularis oxysterol binding protein 1 0.0091 0.0084 0.0095
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0091 0.0084 0.0095
Brugia malayi Protein kinase domain containing protein 0.0321 0.0461 0.0456
Echinococcus multilocularis Pleckstrin y 0.0091 0.0084 0.0095
Leishmania major protein kinase, putative 0.0091 0.0083 0.5095
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0186 0.024 0.1533
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0116 0.0125 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0116 0.0125 0.0551
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis tyrosine protein kinase Abl 0.0065 0.004 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Echinococcus multilocularis semaphorin 5B 0.0426 0.0632 0.075
Brugia malayi Pleckstrin Homology Domain 0.0091 0.0084 0.008
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Trypanosoma cruzi PH domain containing protein, putative 0.0091 0.0084 0.5229
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus granulosus tyrosine kinase 0.0065 0.004 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0083 0.0531
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Brugia malayi Tyrosine-protein kinase abl-1 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis centaurin/arf, putative 0.0091 0.0084 0.0539
Echinococcus multilocularis Pleckstrin y 0.0091 0.0084 0.0095
Schistosoma mansoni protein kinase 0.0091 0.0083 0.0072
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Schistosoma mansoni plexin 0.1004 0.1579 0.157
Schistosoma mansoni hypothetical protein 0.0091 0.0084 0.0073
Echinococcus granulosus pdz domain containing protein 0.0091 0.0084 0.0095
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis tyrosine protein kinase Blk 0.0065 0.004 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0116 0.0125 1
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0091 0.0084 0.0095
Echinococcus granulosus Pleckstrin y 0.0091 0.0084 0.0095
Schistosoma mansoni hypothetical protein 0.0091 0.0084 0.0073
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus raf serine:threonine protein kinase 0.0065 0.004 0.0043
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0065 0.004 0.0043
Echinococcus granulosus regulator of G protein signaling 7 0.0996 0.1567 0.1868
Echinococcus granulosus twitchin 0.0156 0.0191 0.0223
Brugia malayi Dynamin 0.0091 0.0084 0.008
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0116 0.0125 1
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0426 0.0632 0.0628
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0116 0.0125 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus multilocularis heat shock protein 70 0.0065 0.004 0.0043
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0091 0.0084 0.0095
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0091 0.0084 0.0095
Onchocerca volvulus 0.1004 0.1579 1
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Entamoeba histolytica hypothetical protein 0.0116 0.0125 0.0551
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0091 0.0084 0.0288
Echinococcus granulosus Immunoglobulin 0.0132 0.0151 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis protein KINase family member (kin 25) 0.0065 0.004 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trypanosoma cruzi Protein kinase B 0.0116 0.0125 1
Echinococcus multilocularis integrin linked protein kinase 0.0065 0.004 0.0043
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0116 0.0125 1
Echinococcus multilocularis epidermal growth factor receptor 0.0065 0.004 0.0043
Echinococcus granulosus integrin linked protein kinase 0.0065 0.004 0.0043
Onchocerca volvulus 0.0091 0.0084 0.0286
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Echinococcus granulosus tyrosine protein kinase csk 0.0065 0.004 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0065 0.004 0.0043
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0186 0.024 0.1533
Trichomonas vaginalis protein transport protein sec7, putative 0.0091 0.0084 0.0539
Echinococcus granulosus tyrosine protein kinase Lyn 0.0089 0.0081 0.0091
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Loa Loa (eye worm) TK/ALK protein kinase 0.0321 0.046 0.0456
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0578 0.0882 0.0878
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis protein tyrosine kinase, putative 0.0065 0.004 0.0258
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0065 0.004 0.0043
Echinococcus multilocularis Regulator of G protein signaling 20 0.0996 0.1567 0.1868
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Loa Loa (eye worm) TK/INSR protein kinase 0.0065 0.004 0.0036
Plasmodium falciparum serine/threonine protein kinase, putative 0.0091 0.0083 0.5095
Trichomonas vaginalis centaurin alpha, putative 0.0091 0.0084 0.0539
Echinococcus granulosus beta-adrenergic receptor kinase 0.4708 0.765 0.9141
Echinococcus multilocularis regulator of G protein signaling 3 0.0996 0.1567 0.1868
Schistosoma mansoni hypothetical protein 0.0578 0.0882 0.0872
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Entamoeba histolytica PH domain containing protein 0.0091 0.0084 0.0288
Echinococcus granulosus regulator of G protein signaling 7 0.0996 0.1567 0.1868
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0091 0.0084 0.0539
Echinococcus multilocularis Ras associated and pleckstrin y 0.0091 0.0084 0.0095
Entamoeba histolytica PH domain containing protein kinase, putative 0.0116 0.0125 0.0551
Entamoeba histolytica hypothetical protein 0.0186 0.024 0.1309
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Schistosoma mansoni axis inhibition protein axin 0.0996 0.1567 0.1557
Schistosoma mansoni plexin 0.0578 0.0882 0.0872
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi hypothetical protein 0.0091 0.0084 0.008
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Loa Loa (eye worm) sema domain-containing protein 0.0426 0.0632 0.0628
Loa Loa (eye worm) hypothetical protein 0.0137 0.0159 0.0155
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0065 0.004 0.0043
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0065 0.004 0.0043
Entamoeba histolytica hypothetical protein 0.0186 0.024 0.1309
Loa Loa (eye worm) TK/RYK protein kinase 0.0065 0.004 0.0036
Leishmania major protein kinase, putative 0.0089 0.0081 0.4771
Loa Loa (eye worm) hypothetical protein 0.0132 0.0151 0.0146
Plasmodium vivax PH domain containing protein 0.0091 0.0084 0.5229
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis roundabout 2 0.0137 0.0159 0.0185
Brugia malayi regulator of G-protein signaling egl-10 0.0996 0.1567 0.1563
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0996 0.1567 0.1563
Plasmodium falciparum oxysterol-binding protein, putative 0.0091 0.0084 0.5229
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0132 0.0151 0.0146
Loa Loa (eye worm) TK/CSK protein kinase 0.0065 0.004 0.0036
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0132 0.0151 0.014
Trypanosoma cruzi PH domain containing protein, putative 0.0091 0.0084 0.5229
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Echinococcus multilocularis activin receptor type 0.0089 0.0081 0.0091
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Schistosoma mansoni dynamin 0.0091 0.0084 0.0073
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0091 0.0084 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi Variant SH3 domain containing protein 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Echinococcus multilocularis pleckstrin y domain containing family A 0.0091 0.0084 0.0095
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trypanosoma cruzi NIMA-related kinase, putative 0.0116 0.0125 1
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus myotubularin protein 13 0.0091 0.0084 0.0095
Schistosoma mansoni myotubularin-related protein 0.0091 0.0084 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0091 0.0084 0.0095
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.5146 0.8368 0.8367
Echinococcus multilocularis regulator of G protein signaling 0.0996 0.1567 0.1868
Brugia malayi serine/threonine protein kinase 6 0.0091 0.0083 0.0079
Trichomonas vaginalis STE family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0089 0.0081 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus granulosus tyrosine protein kinase Blk 0.0065 0.004 0.0043
Echinococcus multilocularis G protein coupled receptor kinase 1 0.3712 0.6018 0.719
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0186 0.024 0.0236
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0065 0.004 0.0043
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0091 0.0084 0.5229
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0996 0.1567 0.1557
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0091 0.0084 0.0095
Trichomonas vaginalis hypothetical protein 0.0091 0.0084 0.0539
Echinococcus multilocularis oxysterol binding protein 3 0.0091 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Echinococcus granulosus semaphorin 5B 0.0426 0.0632 0.075
Brugia malayi Plexin repeat family protein 0.1004 0.1579 0.1576
Onchocerca volvulus outspread protein homolog 0.0091 0.0084 0.0286
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0196 0.0257 0.0252
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0996 0.1567 0.1868
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0091 0.0083 0.5095
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0996 0.1567 0.1868
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Loa Loa (eye worm) RGC/RGC protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0065 0.004 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis alpha chimerin, putative 0.0091 0.0084 0.0539
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.0083 0.0281
Schistosoma mansoni zinc finger protein 0.0091 0.0084 0.0073
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0089 0.0081 0.4771
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0065 0.004 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus fibroblast growth factor receptor 4 0.0065 0.004 0.0043
Entamoeba histolytica cell surface protease gp63, putative 0.0186 0.024 0.1309
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.5146 0.8368 0.8367
Trypanosoma cruzi hypothetical protein 0.0091 0.0084 0.5229
Brugia malayi serine/threonine-protein kinase 6 0.0091 0.0083 0.0079
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.5146 0.8368 1
Toxoplasma gondii protein kinase domain-containing protein 0.0116 0.0125 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0065 0.004 0.0036
Echinococcus granulosus pleckstrin y domain containing family A 0.0091 0.0084 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0996 0.1567 1
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0091 0.0084 0.0073
Brugia malayi SH2 domain containing protein 0.0065 0.004 0.0036
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.004 0.0029
Schistosoma mansoni protein tyrosine kinase 0.0065 0.004 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Loa Loa (eye worm) AUR protein kinase 0.0091 0.0083 0.0079
Brugia malayi DNA-binding protein LAG-1 0.0186 0.024 0.0236
Brugia malayi regulator of G-protein signaling rgs-7 0.0996 0.1567 0.1563
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Schistosoma mansoni zinc finger protein 0.0091 0.0084 0.0073
Brugia malayi Raf kinase 0.0065 0.004 0.0036
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0065 0.004 0.0043
Schistosoma mansoni z-protein (S1r protein) 0.0996 0.1567 0.1557
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Echinococcus multilocularis Pleckstrin y 0.0091 0.0084 0.0095
Trichomonas vaginalis protein transport protein sec7, putative 0.0091 0.0084 0.0539
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0996 0.1567 1
Echinococcus granulosus tyrosine kinase 0.0065 0.004 0.0043
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus tyrosine protein kinase 0.0065 0.004 0.0043
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Schistosoma mansoni hypothetical protein 0.0091 0.0084 0.0073
Brugia malayi SH2 domain containing protein 0.0065 0.004 0.0036
Brugia malayi Syntrophin-1 0.0091 0.0084 0.008
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Echinococcus granulosus Pleckstrin y 0.0091 0.0084 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0065 0.004 0.0036
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0116 0.0125 1
Brugia malayi Fibronectin type III domain containing protein 0.0137 0.0159 0.0155
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Brugia malayi Sema domain containing protein 0.0426 0.0632 0.0628
Brugia malayi Plekhf2 protein 0.0091 0.0084 0.008
Schistosoma mansoni goodpasture antigen-binding protein 0.0091 0.0084 0.0073
Echinococcus multilocularis Immunoglobulin 0.0132 0.0151 0.0175
Echinococcus multilocularis Oxysterol binding protein 11 0.0091 0.0084 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Brugia malayi Tyrosine-protein kinase PR2 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Plasmodium falciparum protein kinase, putative 0.0089 0.0081 0.4771
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trypanosoma brucei protein kinase, putative 0.0116 0.0125 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0091 0.0084 0.5229
Echinococcus granulosus Rho GTPase activating protein 24 0.0091 0.0084 0.0095
Echinococcus granulosus tyrosine protein kinase csk 0.0065 0.004 0.0043
Loa Loa (eye worm) plexin A 0.119 0.1885 0.1881
Brugia malayi integrin-linked kinase 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus Regulator of G protein signaling 20 0.0996 0.1567 0.1868
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus regulator of G protein signaling 3 0.0996 0.1567 0.1868
Loa Loa (eye worm) TK/DDR protein kinase 0.0065 0.004 0.0036
Onchocerca volvulus 0.0091 0.0084 0.0286
Onchocerca volvulus 0.0091 0.0084 0.0286
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0065 0.004 0.0043
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus granulosus oxysterol binding protein 3 0.0091 0.0084 0.0095
Schistosoma mansoni syntrophin 0.0091 0.0084 0.0073
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0089 0.0081 0.4771
Loa Loa (eye worm) hypothetical protein 0.0137 0.0159 0.0155
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Leishmania major hypothetical protein, conserved 0.0091 0.0084 0.5229
Echinococcus multilocularis dynamin 1 0.0091 0.0084 0.0095
Echinococcus multilocularis plexin a4 0.119 0.1885 0.2248
Brugia malayi Immunoglobulin I-set domain containing protein 0.0196 0.0257 0.0252
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0091 0.0083 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0996 0.1567 1
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus granulosus retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0091 0.0084 0.0095
Brugia malayi plexin A 0.119 0.1885 0.1881
Toxoplasma gondii Oxysterol-binding protein 0.0091 0.0084 0.5229
Loa Loa (eye worm) hypothetical protein 0.0426 0.0632 0.0628
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Schistosoma mansoni fibrocystin l 0.0186 0.024 0.0229
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Echinococcus multilocularis oxysterol binding protein 9 0.0091 0.0084 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0065 0.004 0.0258
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Echinococcus multilocularis tyrosine kinase 0.0065 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0091 0.0084 0.5229
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0091 0.0084 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.6142 1 1
Echinococcus multilocularis Rho GTPase activating protein 24 0.0091 0.0084 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0996 0.1567 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0065 0.004 0.0043
Echinococcus granulosus aurora kinase A 0.0091 0.0083 0.0094
Echinococcus granulosus beta 1 syntrophin 0.0091 0.0084 0.0095
Echinococcus granulosus expressed protein 0.0996 0.1567 0.1868
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0065 0.004 0.0043
Loa Loa (eye worm) serine/threonine protein kinase 0.0065 0.004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Brugia malayi PH domain containing protein 0.0091 0.0084 0.008
Echinococcus granulosus activated cdc42 kinase 1 0.0065 0.004 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0116 0.0125 1
Echinococcus granulosus G protein coupled receptor kinase 1 0.3712 0.6018 0.719
Entamoeba histolytica protein kinase, putative 0.0116 0.0125 0.0551
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0116 0.0125 1
Echinococcus multilocularis natriuretic peptide receptor 1 0.0065 0.004 0.0043
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0089 0.0081 0.4771
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0091 0.0084 0.0288
Toxoplasma gondii AtPH1 family protein 0.0091 0.0084 0.5229
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Echinococcus granulosus semaphorin 1A 0.0426 0.0632 0.075
Entamoeba histolytica hypothetical protein 0.0186 0.024 0.1309
Echinococcus granulosus protein tyrosine kinase 0.0065 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0426 0.0632 0.0628
Echinococcus multilocularis tyrosine protein kinase HCK 0.0065 0.004 0.0043
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0996 0.1567 0.1557
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0083 0.0531
Brugia malayi Uncoordinated protein 104 0.0091 0.0084 0.008
Schistosoma mansoni regulator of G protein signaling 0.0996 0.1567 0.1557
Trypanosoma brucei PH domain containing protein, putative 0.0091 0.0084 0.5229
Echinococcus granulosus DCC interacting protein 13 beta 0.0091 0.0084 0.0095
Leishmania major protein kinase, putative 0.0116 0.0125 1
Echinococcus multilocularis activated cdc42 kinase 1 0.0065 0.004 0.0043
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0091 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0065 0.004 0.0043
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0091 0.0084 0.0539
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0083 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0996 0.1567 1
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0091 0.0084 0.5229
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0065 0.004 0.0036
Brugia malayi SRC-1 0.0065 0.004 0.0036
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0065 0.004 0.0043
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0065 0.004 0.0036
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.0081 0.0263
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Trypanosoma brucei aurora B kinase 0.0091 0.0083 0.5095
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0091 0.0083 0.0281
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.0036
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0116 0.0125 1
Schistosoma mansoni protein kinase 0.0089 0.0081 0.007
Echinococcus granulosus activin receptor type 0.0089 0.0081 0.0091
Brugia malayi Furin-like cysteine rich region family protein 0.0065 0.004 0.0036
Schistosoma mansoni serine/threonine-protein kinase 0.0116 0.0125 0.0114
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0065 0.004 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0083 0.0531
Trichomonas vaginalis protein kinase atn1, putative 0.0065 0.004 0.0258
Echinococcus granulosus insulin receptor 0.0065 0.004 0.0043
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0091 0.0084 0.008
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Entamoeba histolytica ARF GTPase activating protein, putative 0.0091 0.0084 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Echinococcus granulosus retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Brugia malayi hypothetical protein 0.0065 0.004 0.0036
Toxoplasma gondii aurora kinase 0.0091 0.0083 0.5095
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.004 0.0029
Brugia malayi Protein kinase domain containing protein 0.0116 0.0125 0.012
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Trypanosoma brucei rac serine-threonine kinase, putative 0.0116 0.0125 1
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0091 0.0084 0.5229
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Echinococcus granulosus Oxysterol binding protein 11 0.0091 0.0084 0.0095
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0116 0.0125 1
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.4708 0.765 0.7647
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Loa Loa (eye worm) SRC-1 0.0065 0.004 0.0036
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0091 0.0084 0.0288
Echinococcus granulosus tyrosine kinase 0.0065 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0065 0.004 0.0043
Brugia malayi hypothetical protein 0.0996 0.1567 0.1563
Brugia malayi hypothetical protein 0.0065 0.004 0.0036
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0091 0.0083 0.0094
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.6142 1 1
Loa Loa (eye worm) TK protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis calcium dependent secretion activator 1 0.0091 0.0084 0.0095
Schistosoma mansoni protein kinase 0.0065 0.004 0.0029
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0065 0.004 0.0043
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0091 0.0084 0.5229
Entamoeba histolytica PH domain containing protein kinase, putative 0.0116 0.0125 0.0551
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0091 0.0084 0.0095
Echinococcus multilocularis regulator of G protein signaling 7 0.0996 0.1567 0.1868
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.004 0.0043
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0065 0.004 0.0258
Schistosoma mansoni regulator of G protein signaling 0.0996 0.1567 0.1557
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0084 0.0539
Echinococcus multilocularis transfer RNA-Thr 0.0065 0.004 0.0043
Brugia malayi hypothetical protein 0.0065 0.004 0.0036
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0091 0.0083 0.0094
Echinococcus granulosus retinal guanylyl cyclase 2 0.0065 0.004 0.0043
Onchocerca volvulus 0.0091 0.0084 0.0286
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Brugia malayi A-kinase anchor protein 10, precursor 0.0996 0.1567 0.1563
Trypanosoma cruzi PH domain containing protein, putative 0.0091 0.0084 0.5229
Loa Loa (eye worm) TK/FER protein kinase 0.0065 0.004 0.0036
Leishmania major folate/biopterin transporter, putative 0.0116 0.0125 1
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0091 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0137 0.0159 0.0155
Echinococcus multilocularis cytohesin 1 0.0091 0.0084 0.0095
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0091 0.0084 0.0288
Echinococcus granulosus tyrosine protein kinase pr2 0.0065 0.004 0.0043
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0065 0.004 0.0258
Toxoplasma gondii hypothetical protein 0.0091 0.0084 0.5229
Schistosoma mansoni hypothetical protein 0.0426 0.0632 0.0622
Schistosoma mansoni serine/threonine protein kinase 0.4708 0.765 0.7647
Echinococcus granulosus plexin a4 0.119 0.1885 0.2248
Loa Loa (eye worm) TK/EGFR protein kinase 0.0065 0.004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0065 0.004 0.0036
Schistosoma mansoni semaphorin 5-related 0.0426 0.0632 0.0622
Schistosoma mansoni tyrosine kinase 0.0065 0.004 0.0029
Brugia malayi ephrin receptor 1 precursor 0.0065 0.004 0.0036
Echinococcus multilocularis axis inhibition protein axin 0.0996 0.1567 0.1868
Echinococcus granulosus neuroglian 0.0132 0.0151 0.0175
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0065 0.004 0.0036
Echinococcus multilocularis protein tyrosine kinase 0.0065 0.004 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.024 0.1533
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Entamoeba histolytica protein kinase , putative 0.0091 0.0083 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Trypanosoma cruzi PH domain containing protein, putative 0.0091 0.0084 0.5229
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Echinococcus multilocularis rac serine:threonine kinase 0.0116 0.0125 0.0143
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0091 0.0084 0.0288
Brugia malayi hypothetical protein 0.0996 0.1567 0.1563
Trichomonas vaginalis centaurin/arf, putative 0.0091 0.0084 0.0539
Brugia malayi IPT/TIG domain containing protein 0.0186 0.024 0.0236
Schistosoma mansoni regulator of G protein signaling 0.0996 0.1567 0.1557
Entamoeba histolytica tyrosin kinase, putative 0.0251 0.0346 0.2002
Loa Loa (eye worm) hypothetical protein 0.0091 0.0084 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.004 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Loa Loa (eye worm) hypothetical protein 0.0132 0.0151 0.0146
Brugia malayi Cytohesin 3 0.0091 0.0084 0.008
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0091 0.0084 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0065 0.004 0.0258
Schistosoma mansoni protein kinase 0.0089 0.0081 0.007
Entamoeba histolytica PH domain containing protein kinase, putative 0.0116 0.0125 0.0551
Schistosoma mansoni hypothetical protein 0.0186 0.024 0.0229
Loa Loa (eye worm) hypothetical protein 0.0996 0.1567 0.1563
Echinococcus granulosus regulator of G protein signaling 3 0.0996 0.1567 0.1868
Echinococcus granulosus epidermal growth factor receptor 0.0065 0.004 0.0043
Schistosoma mansoni cell adhesion molecule 0.0137 0.0159 0.0149
Entamoeba histolytica protein kinase, putative 0.0091 0.0083 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0125 0.0795
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0065 0.004 0.0036
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0116 0.0125 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0065 0.004 0.0043
Echinococcus granulosus activated cdc42 kinase 1 0.0065 0.004 0.0043
Loa Loa (eye worm) PXA domain-containing protein 0.0996 0.1567 0.1563

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 195 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays: 2118 (Project Summary), 2098 (Primary HTS)] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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