TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 373.554 | Formula: C26H33N2+
H donors: 1 H acceptors: 0 LogP: 8.33 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: C(CC[n+]1cc(Nc2ccccc2)cc2c1cccc2)CCC1CCCCC1
InChi: 1S/C26H33N2/c1-4-12-22(13-5-1)14-6-3-11-19-28-21-25(27-24-16-7-2-8-17-24)20-23-15-9-10-18-26(23)28/h2,7-10,15-18,20-22,27H,1,3-6,11-14,19H2/q+1
InChiKey: LSOCYSGCDSKWRO-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0058	0.004	0.0041
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0153	0.0147
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Trichomonas vaginalis	AGC family protein kinase	0.008	0.0083	0.0533
Entamoeba histolytica	hypothetical protein, conserved	0.0074	0.0072	0.0212
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0058	0.004	0.0041
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0074	0.0072	0.0079
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0809	0.1556	0.1855
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0074	0.0072	0.0212
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Onchocerca volvulus		0.0913	0.1765	1
Brugia malayi	SH2 domain containing protein	0.0058	0.004	0.0034
Schistosoma mansoni	serine/threonine protein kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	AGC family protein kinase	0.008	0.0083	0.0533
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Brugia malayi	Oxysterol-binding protein	0.0074	0.0072	0.0066
Trypanosoma cruzi	NIMA-related kinase, putative	0.0094	0.0112	1
Echinococcus granulosus	twitchin	0.0134	0.0193	0.0224
Loa Loa (eye worm)	TK/INSR protein kinase	0.0058	0.004	0.0034
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0074	0.0072	0.0079
Schistosoma mansoni	serine/threonine RGC	0.0058	0.004	0.0027
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0173	0.0271	0.0265
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0058	0.004	0.0041
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Loa Loa (eye worm)	TK/ABL protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0153	0.0147
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0058	0.004	0.0041
Trypanosoma brucei	aurora B kinase	0.008	0.0083	0.5963
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Brugia malayi	Uncoordinated protein 104	0.0074	0.0072	0.0066
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0074	0.0072	0.0079
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	tyrosine protein kinase shark	0.0058	0.004	0.0041
Schistosoma mansoni	serine/threonine protein kinase	0.3827	0.7647	0.7644
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	pdz domain containing protein	0.0074	0.0072	0.0079
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0074	0.0072	0.0212
Entamoeba histolytica	hypothetical protein	0.017	0.0264	0.1481
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Trichomonas vaginalis	STE family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0058	0.004	0.0027
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0074	0.0072	0.0212
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0074	0.0072	0.0462
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Giardia lamblia	Aurora kinase	0.008	0.0083	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0058	0.004	0.0041
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus granulosus	regulator of G protein signaling 7	0.0809	0.1556	0.1855
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Brugia malayi	Tyrosine-protein kinase abl-1	0.0058	0.004	0.0034
Echinococcus multilocularis	tyrosine protein kinase csk	0.0058	0.004	0.0041
Trypanosoma cruzi	aurora B kinase, putative	0.008	0.0083	0.5963
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0074	0.0072	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Schistosoma mansoni	nephrin	0.0119	0.0163	0.015
Loa Loa (eye worm)	TK/FAK protein kinase	0.0058	0.004	0.0034
Schistosoma mansoni	protein kinase	0.008	0.0083	0.007
Schistosoma mansoni	vesicular amine transporter	0.0117	0.0158	0.0145
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	regulator of G protein signaling	0.0809	0.1556	0.1545
Brugia malayi	Oxysterol binding protein	0.0074	0.0072	0.0066
Echinococcus multilocularis	regulator of G protein signaling 7	0.0809	0.1556	0.1855
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0074	0.0072	0.0079
Echinococcus granulosus	pleckstrin y domain containing family A	0.0074	0.0072	0.0079
Echinococcus granulosus	roundabout 2	0.0119	0.0163	0.0188
Brugia malayi	Plekhf2 protein	0.0074	0.0072	0.0066
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Echinococcus multilocularis	oxysterol binding protein 3	0.0074	0.0072	0.0079
Trichomonas vaginalis	conserved hypothetical protein	0.0809	0.1556	1
Echinococcus granulosus	integrin linked protein kinase	0.0058	0.004	0.0041
Echinococcus granulosus	activated cdc42 kinase 1	0.0058	0.004	0.0041
Echinococcus granulosus	kinase suppressor of Ras 1	0.0058	0.004	0.0041
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.008	0.0083	0.0093
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0094	0.0112	1
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	transcription factor collier	0.017	0.0264	0.0309
Echinococcus granulosus	myotubularin protein 13	0.0074	0.0072	0.0079
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	cytohesin 1	0.0074	0.0072	0.0079
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0809	0.1556	0.1545
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0526	0.0983	0.0978
Loa Loa (eye worm)	TK/CSK protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	neuroglian	0.0114	0.0153	0.0176
Trypanosoma brucei	PH domain containing protein, putative	0.0074	0.0072	0.4441
Echinococcus granulosus	tyrosine kinase	0.0058	0.004	0.0041
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.008	0.0083	0.0285
Entamoeba histolytica	protein kinase domain containing protein	0.008	0.0083	0.0285
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0074	0.0072	0.0066
Echinococcus granulosus	Pleckstrin y	0.0074	0.0072	0.0079
Onchocerca volvulus		0.0074	0.0072	0.0187
Entamoeba histolytica	p21-activated kinase	0.0094	0.0112	0.0478
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0074	0.0072	0.4441
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Schistosoma mansoni	hypothetical protein	0.0074	0.0072	0.0059
Trichomonas vaginalis	centaurin/arf, putative	0.0074	0.0072	0.0462
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.0094	0.0112	1
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0074	0.0072	0.0059
Onchocerca volvulus		0.0074	0.0072	0.0187
Echinococcus multilocularis	Immunoglobulin	0.0114	0.0153	0.0176
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.0094	0.0112	1
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0058	0.004	0.0041
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Brugia malayi	Pleckstrin Homology Domain	0.0074	0.0072	0.0066
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	Pleckstrin y	0.0074	0.0072	0.0079
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0058	0.004	0.0041
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0074	0.0072	0.0079
Schistosoma mansoni	hypothetical protein	0.0387	0.0703	0.0691
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Trypanosoma brucei	protein kinase, putative	0.0078	0.008	0.5559
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0094	0.0112	1
Schistosoma mansoni	protein kinase	0.0078	0.008	0.0067
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0074	0.0072	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0058	0.004	0.0255
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0058	0.004	0.0041
Echinococcus multilocularis	integrin linked protein kinase	0.0058	0.004	0.0041
Brugia malayi	serine/threonine-protein kinase 6	0.008	0.0083	0.0077
Brugia malayi	Cytohesin 3	0.0074	0.0072	0.0066
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0809	0.1556	0.1855
Loa Loa (eye worm)	hypothetical protein	0.0809	0.1556	0.1551
Echinococcus multilocularis	myotubularin protein 13	0.0074	0.0072	0.0079
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0809	0.1556	0.1545
Echinococcus multilocularis	tyrosine protein kinase csk	0.0058	0.004	0.0041
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0058	0.004	0.0041
Echinococcus multilocularis	expressed protein	0.0809	0.1556	0.1855
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Onchocerca volvulus		0.0387	0.0703	0.3847
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Echinococcus granulosus	exocyst complex component 2	0.017	0.0264	0.0309
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	hypothetical protein	0.017	0.0264	0.1481
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Echinococcus multilocularis	heat shock protein 70	0.0058	0.004	0.0041
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.017	0.0264	0.1698
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0058	0.004	0.0255
Schistosoma mansoni	hypothetical protein	0.0074	0.0072	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Brugia malayi	hypothetical protein	0.0387	0.0703	0.0698
Schistosoma mansoni	serine/threonine protein kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Entamoeba histolytica	hypothetical protein	0.0809	0.1556	1
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0058	0.004	0.0041
Brugia malayi	C-terminal src kinase protein 1	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0153	0.0147
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0058	0.004	0.0041
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0078	0.008	0.0089
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0114	0.0153	0.0176
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Echinococcus multilocularis	Oxysterol binding protein 11	0.0074	0.0072	0.0079
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0074	0.0072	0.0462
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0058	0.004	0.0041
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Brugia malayi	Sema domain containing protein	0.0387	0.0703	0.0698
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	hypothetical protein	0.0074	0.0072	0.0059
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0058	0.004	0.0041
Trypanosoma cruzi	NIMA-related kinase, putative	0.0094	0.0112	1
Onchocerca volvulus	Putative zinc finger protein	0.0074	0.0072	0.0187
Brugia malayi	Cadps2 protein	0.0074	0.0072	0.0066
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Echinococcus multilocularis	epidermal growth factor receptor	0.0058	0.004	0.0041
Echinococcus multilocularis	oxysterol binding protein 9	0.0074	0.0072	0.0079
Loa Loa (eye worm)	TK/ROR protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	hypothetical protein	0.0074	0.0072	0.0059
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0153	0.0147
Echinococcus granulosus	neuroglian	0.0114	0.0153	0.0176
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Brugia malayi	regulator of G-protein signaling rgs-7	0.0809	0.1556	0.1551
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	growth factor receptor-bound protein	0.0074	0.0072	0.0059
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Entamoeba histolytica	hypothetical protein	0.0074	0.0072	0.0212
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	transcription factor collier	0.017	0.0264	0.0309
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0074	0.0072	0.0462
Loa Loa (eye worm)	AUR protein kinase	0.008	0.0083	0.0077
Brugia malayi	ephrin receptor 1 precursor	0.0058	0.004	0.0034
Onchocerca volvulus		0.0074	0.0072	0.0187
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0094	0.0112	0.0478
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0094	0.0112	0.0478
Brugia malayi	hypothetical protein	0.0074	0.0072	0.0066
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0058	0.004	0.0041
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	AUR protein kinase	0.008	0.0083	0.0077
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0809	0.1556	0.1551
Schistosoma mansoni	hypothetical protein	0.0058	0.004	0.0027
Echinococcus multilocularis	actin binding protein anillin	0.0074	0.0072	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0387	0.0703	0.0698
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0058	0.004	0.0041
Plasmodium falciparum	PH domain-containing protein, putative	0.0074	0.0072	0.4441
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0074	0.0072	0.0079
Schistosoma mansoni	hypothetical protein	0.017	0.0264	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0074	0.0072	0.0079
Brugia malayi	Syntrophin-1	0.0074	0.0072	0.0066
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0074	0.0072	0.4441
Loa Loa (eye worm)	TK/ACK protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	activin receptor type	0.0078	0.008	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0217	0.036	0.0355
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	tyrosine protein kinase	0.0058	0.004	0.0027
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.0094	0.0112	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Entamoeba histolytica	tyrosin kinase, putative	0.0228	0.0382	0.2257
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.008	0.0083	0.0285
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0058	0.004	0.0041
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.0094	0.0112	1
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0094	0.0112	1
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Schistosoma mansoni	goodpasture antigen-binding protein	0.0074	0.0072	0.0059
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	protein kinase, putative	0.008	0.0083	0.0285
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0094	0.0112	0.0478
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.017	0.0264	0.1698
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0074	0.0072	0.0079
Echinococcus multilocularis	exocyst complex component 2	0.017	0.0264	0.0309
Schistosoma mansoni	ephrin receptor	0.0063	0.005	0.0037
Brugia malayi	regulator of G-protein signaling egl-10	0.0809	0.1556	0.1551
Echinococcus granulosus	defective proboscis extension response	0.0114	0.0153	0.0176
Brugia malayi	Protein kinase domain containing protein	0.0094	0.0112	0.0107
Loa Loa (eye worm)	TK/Met protein kinase	0.0058	0.004	0.0034
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0094	0.0112	1
Loa Loa (eye worm)	TK/EPH protein kinase	0.0058	0.004	0.0034
Brugia malayi	Furin-like cysteine rich region family protein	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	epidermal growth factor receptor	0.0058	0.004	0.0041
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0074	0.0072	0.0066
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Brugia malayi	hypothetical protein	0.0058	0.004	0.0034
Entamoeba histolytica	hypothetical protein	0.0074	0.0072	0.0212
Leishmania major	protein kinase, putative	0.0094	0.0112	1
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.0094	0.0112	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	hypothetical protein	0.0913	0.1765	0.176
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0058	0.004	0.0034
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0074	0.0072	0.0462
Trichomonas vaginalis	centaurin gamma, putative	0.0074	0.0072	0.0462
Echinococcus multilocularis	c src tyrosine kinase	0.0058	0.004	0.0041
Echinococcus granulosus	activated cdc42 kinase 1	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0074	0.0072	0.4441
Echinococcus granulosus	oxysterol binding protein 3	0.0074	0.0072	0.0079
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus granulosus	semaphorin 1A	0.0387	0.0703	0.0835
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Trichomonas vaginalis	centaurin beta, putative	0.0074	0.0072	0.0462
Echinococcus multilocularis	protein tyrosine kinase	0.0058	0.004	0.0041
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0058	0.004	0.0041
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0074	0.0072	0.0066
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Brugia malayi	Fibronectin type III domain containing protein	0.0119	0.0163	0.0158
Echinococcus granulosus	Regulator of G protein signaling 20	0.0809	0.1556	0.1855
Plasmodium vivax	PH domain containing protein	0.0074	0.0072	0.4441
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Schistosoma mansoni	oxysterol-binding protein 1	0.0074	0.0072	0.0059
Loa Loa (eye worm)	Plekhf2 protein	0.0074	0.0072	0.0066
Schistosoma mansoni	serine/threonine protein kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	conserved hypothetical protein	0.0809	0.1556	1
Leishmania major	protein kinase, putative	0.0094	0.0112	1
Echinococcus granulosus	calcium dependent secretion activator 1	0.0074	0.0072	0.0079
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0058	0.004	0.0041
Entamoeba histolytica	hypothetical protein	0.0094	0.0112	0.0478
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.0094	0.0112	1
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Onchocerca volvulus	outspread protein homolog	0.0074	0.0072	0.0187
Brugia malayi	hypothetical protein	0.0387	0.0703	0.0698
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.0094	0.0112	0.0721
Echinococcus granulosus	pdz domain containing protein	0.0074	0.0072	0.0079
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0058	0.004	0.0041
Echinococcus granulosus	tyrosine protein kinase csk	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Schistosoma mansoni	hypothetical protein	0.0074	0.0072	0.0059
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0094	0.0112	0.0107
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0058	0.004	0.0027
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Plasmodium vivax	hypothetical protein, conserved	0.0074	0.0072	0.4441
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Schistosoma mansoni	hypothetical protein	0.017	0.0264	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	syntrophin	0.0074	0.0072	0.0059
Echinococcus granulosus	Oxysterol binding protein 11	0.0074	0.0072	0.0079
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0114	0.0153	0.0176
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	conserved hypothetical protein	0.0809	0.1556	1
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	Pleckstrin y	0.0074	0.0072	0.0079
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.017	0.0264	0.0259
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0094	0.0112	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0058	0.004	0.0034
Schistosoma mansoni	regulator of G protein signaling	0.0809	0.1556	0.1545
Loa Loa (eye worm)	hypothetical protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0058	0.004	0.0255
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0074	0.0072	0.4441
Brugia malayi	Probable exocyst complex component Sec5	0.017	0.0264	0.0259
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0305	0.0537	0.0532
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	PH domain containing protein	0.0074	0.0072	0.0212
Echinococcus multilocularis	protein kinase	0.0058	0.004	0.0041
Schistosoma mansoni	serine/threonine protein kinase	0.3827	0.7647	0.7644
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Entamoeba histolytica	PH domain containing protein	0.0074	0.0072	0.0212
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Brugia malayi	Guanylyl cyclase protein 23	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0387	0.0703	0.0698
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus multilocularis	tyrosine protein kinase	0.0058	0.004	0.0041
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Echinococcus granulosus	GRB2 associated binding protein 3	0.0074	0.0072	0.0079
Schistosoma mansoni	protein kinase	0.0078	0.008	0.0067
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0058	0.004	0.0034
Brugia malayi	Raf kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0078	0.008	0.5559
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0074	0.0072	0.0079
Loa Loa (eye worm)	RGS-3 protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus multilocularis	activated cdc42 kinase 1	0.0058	0.004	0.0041
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0058	0.004	0.0041
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0058	0.004	0.0041
Toxoplasma gondii	Oxysterol-binding protein	0.0074	0.0072	0.4441
Loa Loa (eye worm)	PH domain-containing protein	0.0074	0.0072	0.0066
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0094	0.0112	0.0478
Brugia malayi	Sema domain containing protein	0.0387	0.0703	0.0698
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Toxoplasma gondii	hypothetical protein	0.0074	0.0072	0.4441
Echinococcus granulosus	epidermal growth factor receptor	0.0058	0.004	0.0041
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0074	0.0072	0.0212
Schistosoma mansoni	dynamin	0.0074	0.0072	0.0059
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Toxoplasma gondii	AtPH1 family protein	0.0074	0.0072	0.4441
Leishmania major	hypothetical protein, conserved	0.0074	0.0072	0.4441
Loa Loa (eye worm)	hypothetical protein	0.0119	0.0163	0.0158
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0058	0.004	0.0041
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0074	0.0072	0.0079
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	conserved hypothetical protein	0.0809	0.1556	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0058	0.004	0.0041
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.3017	0.6013	0.7186
Onchocerca volvulus		0.0074	0.0072	0.0187
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0074	0.0072	0.0059
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.008	0.0083	0.5963
Echinococcus multilocularis	regulator of G protein signaling 7	0.0809	0.1556	0.1855
Schistosoma mansoni	protein kinase	0.0078	0.008	0.0067
Echinococcus multilocularis	regulator of G protein signaling 3	0.0809	0.1556	0.1855
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0074	0.0072	0.0079
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	serine/threonine protein kinase	0.008	0.0083	0.007
Brugia malayi	hypothetical protein	0.0058	0.004	0.0034
Echinococcus multilocularis	regulator of G protein signaling 3	0.0809	0.1556	0.1855
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.4183	0.8366	0.8365
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0809	0.1556	0.1545
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0387	0.0703	0.0698
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Trypanosoma cruzi	PH domain containing protein, putative	0.0074	0.0072	0.4441
Loa Loa (eye worm)	TK/DDR protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0058	0.004	0.0041
Toxoplasma gondii	hypothetical protein	0.0074	0.0072	0.4441
Schistosoma mansoni	dynamin	0.0074	0.0072	0.0059
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0058	0.004	0.0041
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0074	0.0072	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	sema domain-containing protein	0.0387	0.0703	0.0698
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0074	0.0072	0.0187
Echinococcus multilocularis	tyrosine kinase	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0058	0.004	0.0027
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	natriuretic peptide receptor 1	0.0058	0.004	0.0041
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Schistosoma mansoni	zinc finger protein	0.0074	0.0072	0.0059
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0074	0.0072	0.0079
Echinococcus multilocularis	semaphorin 5B	0.0387	0.0703	0.0835
Leishmania major	protein kinase, putative	0.0078	0.008	0.5559
Trichomonas vaginalis	hypothetical protein	0.0074	0.0072	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Schistosoma mansoni	axis inhibition protein axin	0.0809	0.1556	0.1545
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0074	0.0072	0.4441
Brugia malayi	Tyrosine-protein kinase PR2	0.0058	0.004	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.0094	0.0112	1
Echinococcus granulosus	axis inhibition protein axin	0.0809	0.1556	0.1855
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0074	0.0072	0.0079
Schistosoma mansoni	regulator of G protein signaling	0.0809	0.1556	0.1545
Trichomonas vaginalis	conserved hypothetical protein	0.0809	0.1556	1
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Echinococcus granulosus	activin receptor type	0.0078	0.008	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0058	0.004	0.0041
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Echinococcus multilocularis	tyrosine protein kinase csk	0.0058	0.004	0.0041
Brugia malayi	hypothetical protein	0.0809	0.1556	0.1551
Brugia malayi	TBC domain containing protein	0.0074	0.0072	0.0066
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0058	0.004	0.0041
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Echinococcus granulosus	tyrosine protein kinase	0.0058	0.004	0.0041
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0058	0.004	0.0041
Brugia malayi	probable spectrin beta chain	0.0074	0.0072	0.0066
Brugia malayi	protein-tyrosine kinase	0.0058	0.004	0.0034
Schistosoma mansoni	z-protein (S1r protein)	0.0809	0.1556	0.1545
Onchocerca volvulus		0.0074	0.0072	0.0187
Brugia malayi	IPT/TIG domain containing protein	0.017	0.0264	0.0259
Loa Loa (eye worm)	cytohesin 3	0.0074	0.0072	0.0066
Brugia malayi	DNA-binding protein LAG-1	0.017	0.0264	0.0259
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.4183	0.8366	0.8365
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Schistosoma mansoni	vav2	0.0074	0.0072	0.0059
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	beta-adrenergic receptor kinase	0.3827	0.7647	0.914
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.0094	0.0112	0.0721
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0119	0.0163	0.0158
Echinococcus multilocularis	FL cytokine receptor	0.0058	0.004	0.0041
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0058	0.004	0.0027
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Brugia malayi	Variant SH3 domain containing protein	0.0074	0.0072	0.0066
Entamoeba histolytica	hypothetical protein	0.0074	0.0072	0.0212
Echinococcus multilocularis	rac serine:threonine kinase	0.0094	0.0112	0.0128
Trichomonas vaginalis	centaurin alpha, putative	0.0074	0.0072	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0153	0.0147
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0074	0.0072	0.0059
Loa Loa (eye worm)	uncoordinated protein 104	0.0074	0.0072	0.0066
Echinococcus granulosus	semaphorin 5B	0.0387	0.0703	0.0835
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0058	0.004	0.0041
Echinococcus granulosus	axis inhibition protein axin	0.0809	0.1556	0.1855
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.008	0.0083	0.0285
Entamoeba histolytica	hypothetical protein	0.0809	0.1556	1
Loa Loa (eye worm)	TK/RYK protein kinase	0.0058	0.004	0.0034
Schistosoma mansoni	rho gtpase activating protein	0.0074	0.0072	0.0059
Echinococcus granulosus	protein tyrosine kinase	0.0058	0.004	0.0041
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0074	0.0072	0.0059
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Echinococcus granulosus	epidermal growth factor receptor	0.0058	0.004	0.0041
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Entamoeba histolytica	protein kinase domain containing protein	0.0078	0.008	0.0266
Plasmodium falciparum	protein kinase, putative	0.0078	0.008	0.5559
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Echinococcus granulosus	regulator of G protein signaling 3	0.0809	0.1556	0.1855
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0058	0.004	0.0041
Echinococcus granulosus	expressed protein	0.0809	0.1556	0.1855
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0058	0.004	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0119	0.0163	0.0158
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0058	0.004	0.0041
Leishmania major	hypothetical protein, conserved	0.0074	0.0072	0.4441
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0074	0.0072	0.0066
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	TK family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	tyrosine protein kinase csk	0.0058	0.004	0.0041
Brugia malayi	SH2 domain containing protein	0.0058	0.004	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus multilocularis	plexin a4	0.1082	0.2107	0.2513
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0058	0.004	0.0041
Trypanosoma cruzi	hypothetical protein	0.0074	0.0072	0.4441
Trypanosoma cruzi	PH domain containing protein, putative	0.0074	0.0072	0.4441
Entamoeba histolytica	protein kinase, putative	0.0094	0.0112	0.0478
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0063	0.005	0.0053
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0063	0.005	0.0053
Echinococcus multilocularis	Pleckstrin y	0.0074	0.0072	0.0079
Loa Loa (eye worm)	hypothetical protein	0.017	0.0264	0.0259
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0058	0.004	0.0041
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Echinococcus granulosus	tyrosine protein kinase pr2	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0074	0.0072	0.0212
Echinococcus granulosus	tyrosine protein kinase Blk	0.0058	0.004	0.0041
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	tyrosine protein kinase Srms	0.0058	0.004	0.0041
Schistosoma mansoni	plexin	0.0526	0.0983	0.0971
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0058	0.004	0.0255
Entamoeba histolytica	protein kinase domain containing protein	0.0228	0.0382	0.2257
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0058	0.004	0.0034
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0058	0.004	0.0041
Plasmodium falciparum	serine/threonine protein kinase, putative	0.008	0.0083	0.5963
Schistosoma mansoni	serine/threonine-protein kinase	0.0094	0.0112	0.0099
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0058	0.004	0.0034
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0114	0.0153	0.014
Echinococcus multilocularis	Pleckstrin y	0.0074	0.0072	0.0079
Leishmania major	serine/threonine-protein kinase a, putative	0.0094	0.0112	1
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0094	0.0112	1
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	hypothetical protein	0.0387	0.0703	0.0835
Echinococcus granulosus	regulator of G protein signaling 7	0.0809	0.1556	0.1855
Echinococcus granulosus	insulin receptor	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.017	0.0264	0.0259
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Entamoeba histolytica	hypothetical protein	0.017	0.0264	0.1481
Entamoeba histolytica	protein kinase, putative	0.008	0.0083	0.0285
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0074	0.0072	0.0079
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0387	0.0703	0.0698
Brugia malayi	hypothetical protein	0.0119	0.0163	0.0158
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0074	0.0072	0.0079
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0074	0.0072	0.0187
Echinococcus granulosus	G protein coupled receptor kinase 1	0.3017	0.6013	0.7186
Toxoplasma gondii	aurora kinase	0.008	0.0083	0.5963
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Schistosoma mansoni	regulator of G protein signaling	0.0809	0.1556	0.1545
Echinococcus granulosus	c src tyrosine kinase	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0074	0.0072	0.0212
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Loa Loa (eye worm)	sema domain-containing protein	0.0387	0.0703	0.0698
Loa Loa (eye worm)	hypothetical protein	0.0809	0.1556	0.1551
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0114	0.0153	0.014
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0074	0.0072	0.0079
Echinococcus granulosus	DCC interacting protein 13 beta	0.0074	0.0072	0.0079
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Trichomonas vaginalis	centaurin/arf, putative	0.0074	0.0072	0.0462
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trypanosoma cruzi	PH domain containing protein, putative	0.0074	0.0072	0.4441
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0074	0.0072	0.4441
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0094	0.0112	1
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0074	0.0072	0.0079
Echinococcus granulosus	Immunoglobulin	0.0114	0.0153	0.0176
Entamoeba histolytica	PH domain containing protein	0.0074	0.0072	0.0212
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0809	0.1556	1
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	roundabout 2	0.0119	0.0163	0.0188
Loa Loa (eye worm)	hypothetical protein	0.0809	0.1556	0.1551
Echinococcus granulosus	receptor type guanylyl cyclase	0.0058	0.004	0.0041
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0058	0.004	0.0041
Echinococcus granulosus	tyrosine protein kinase HCK	0.0058	0.004	0.0041
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0058	0.004	0.0027
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	Pleckstrin y	0.0074	0.0072	0.0079
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Schistosoma mansoni	cell adhesion molecule	0.0119	0.0163	0.015
Echinococcus granulosus	plexin a4	0.1082	0.2107	0.2513
Echinococcus granulosus	ephrin type A receptor 4 A	0.0058	0.004	0.0041
Echinococcus multilocularis	cytohesin 1	0.0074	0.0072	0.0079
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0094	0.0112	1
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0058	0.004	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	dynamin 1	0.0074	0.0072	0.0079
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0074	0.0072	0.0066
Schistosoma mansoni	hypothetical protein	0.0526	0.0983	0.0971
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.4183	0.8366	1
Trichomonas vaginalis	AGC family protein kinase	0.008	0.0083	0.0533
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0074	0.0072	0.4441
Plasmodium falciparum	oxysterol-binding protein, putative	0.0074	0.0072	0.4441
Schistosoma mansoni	protein tyrosine kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	aurora kinase A	0.008	0.0083	0.0093
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	beta adrenergic receptor kinase	0.3827	0.7647	0.914
Echinococcus granulosus	protein kinase	0.0058	0.004	0.0041
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0058	0.004	0.0041
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0074	0.0072	0.4441
Echinococcus multilocularis	protein kinase	0.0058	0.004	0.0041
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus multilocularis	axis inhibition protein axin	0.0809	0.1556	0.1855
Entamoeba histolytica	hypothetical protein	0.0074	0.0072	0.0212
Echinococcus granulosus	tyrosine protein kinase csk	0.0058	0.004	0.0041
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0058	0.004	0.0034
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0094	0.0112	0.0478
Schistosoma mansoni	myotubularin-related protein	0.0074	0.0072	0.0059
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus multilocularis	tyrosine kinase	0.0058	0.004	0.0041
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.017	0.0264	0.1698
Echinococcus granulosus	oxysterol binding protein 9	0.0074	0.0072	0.0079
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Brugia malayi	serine/threonine kinase 12	0.008	0.0083	0.0077
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trypanosoma cruzi	Protein kinase B	0.0094	0.0112	1
Brugia malayi	SRC-1	0.0058	0.004	0.0034
Brugia malayi	MAX-1A	0.0074	0.0072	0.0066
Echinococcus multilocularis	axis inhibition protein axin	0.0809	0.1556	0.1855
Loa Loa (eye worm)	hypothetical protein	0.017	0.0264	0.0259
Leishmania major	protein kinase, putative	0.008	0.0083	0.5963
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	aurora kinase A	0.008	0.0083	0.0093
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0058	0.004	0.0041
Echinococcus multilocularis	dynamin 1	0.0074	0.0072	0.0079
Trichomonas vaginalis	alpha chimerin, putative	0.0074	0.0072	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0119	0.0163	0.0158
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0074	0.0072	0.0462
Toxoplasma gondii	protein kinase domain-containing protein	0.0094	0.0112	1
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0058	0.004	0.0041
Schistosoma mansoni	oxysterol-binding protein 1	0.0074	0.0072	0.0059
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0809	0.1556	0.1551
Schistosoma mansoni	serine/threonine-protein kinase	0.0094	0.0112	0.0099
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.4183	0.8366	0.8365
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0058	0.004	0.0041
Brugia malayi	PXA domain containing protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Trichomonas vaginalis	protein kinase atn1, putative	0.0058	0.004	0.0255
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.0094	0.0112	1
Entamoeba histolytica	hypothetical protein	0.0094	0.0112	0.0478
Brugia malayi	A-kinase anchor protein 10, precursor	0.0809	0.1556	0.1551
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0078	0.008	0.5559
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0078	0.008	0.0089
Echinococcus granulosus	oxysterol binding protein 1	0.0074	0.0072	0.0079
Trypanosoma brucei	protein kinase, putative	0.0094	0.0112	1
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Echinococcus multilocularis	insulin receptor	0.0058	0.004	0.0041
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0058	0.004	0.0034
Onchocerca volvulus		0.0074	0.0072	0.0187
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0173	0.0271	0.0265
Brugia malayi	PXA domain containing protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.017	0.0264	0.1698
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Schistosoma mansoni	hypothetical protein	0.0387	0.0703	0.0691
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Schistosoma mansoni	plexin	0.0913	0.1765	0.1754
Schistosoma mansoni	serine/threonine protein kinase	0.0058	0.004	0.0027
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.3827	0.7647	0.7646
Schistosoma mansoni	semaphorin 5-related	0.0387	0.0703	0.0691
Brugia malayi	Dynamin	0.0074	0.0072	0.0066
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0058	0.004	0.0255
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Schistosoma mansoni	regulator of G protein signaling	0.0809	0.1556	0.1545
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	PXA domain-containing protein	0.0809	0.1556	0.1551
Brugia malayi	hypothetical protein	0.0809	0.1556	0.1551
Trichomonas vaginalis	conserved hypothetical protein	0.0809	0.1556	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0094	0.0112	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0058	0.004	0.0041
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0074	0.0072	0.4441
Echinococcus multilocularis	Immunoglobulin	0.0114	0.0153	0.0176
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Loa Loa (eye worm)	oxysterol binding protein	0.0074	0.0072	0.0066
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0074	0.0072	0.4441
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0153	0.0147
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0094	0.0112	1
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0058	0.004	0.0027
Schistosoma mansoni	fibrocystin l	0.017	0.0264	0.0251
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0074	0.0072	0.0079
Leishmania major	folate/biopterin transporter, putative	0.0094	0.0112	1
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.017	0.0264	0.1698
Schistosoma mansoni	ephrin receptor	0.0058	0.004	0.0027
Loa Loa (eye worm)	TK protein kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0058	0.004	0.0034
Loa Loa (eye worm)	TK/ALK protein kinase	0.0305	0.0537	0.0532
Echinococcus multilocularis	oxysterol binding protein 1	0.0074	0.0072	0.0079
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0078	0.008	0.0089
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Loa Loa (eye worm)	rho-GTPase-activating	0.0074	0.0072	0.0066
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.017	0.0264	0.1698
Brugia malayi	Plexin repeat family protein	0.0913	0.1765	0.176
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.008	0.0083	0.0093
Brugia malayi	Dynamin	0.0074	0.0072	0.0066
Trypanosoma cruzi	PH domain containing protein, putative	0.0074	0.0072	0.4441
Brugia malayi	plexin A	0.1082	0.2107	0.2103
Brugia malayi	PH domain containing protein	0.0074	0.0072	0.0066
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0058	0.004	0.0041
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Echinococcus granulosus	regulator of G protein signaling 3	0.0809	0.1556	0.1855
Trichomonas vaginalis	AGC family protein kinase	0.008	0.0083	0.0533
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Echinococcus granulosus	tyrosine kinase	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Brugia malayi	integrin-linked kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0058	0.004	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Onchocerca volvulus		0.0074	0.0072	0.0187
Brugia malayi	Receptor family ligand binding region containing protein	0.0058	0.004	0.0034
Echinococcus granulosus	serine/threonine protein kinase	0.0094	0.0112	0.0128
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0074	0.0072	0.0462
Loa Loa (eye worm)	plexin A	0.1082	0.2107	0.2103
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.0094	0.0112	1
Entamoeba histolytica	protein kinase , putative	0.008	0.0083	0.0285
Loa Loa (eye worm)	AUR protein kinase	0.008	0.0083	0.0077
Trichomonas vaginalis	CAMK family protein kinase	0.0058	0.004	0.0255
Brugia malayi	hypothetical protein	0.0058	0.004	0.0034
Schistosoma mansoni	axis inhibition protein axin	0.0809	0.1556	0.1545
Schistosoma mansoni	goodpasture antigen-binding protein	0.0074	0.0072	0.0059
Schistosoma mansoni	centaurin alpha	0.0074	0.0072	0.0059
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0809	0.1556	0.1855
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.4183	0.8366	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0072	0.0066
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0058	0.004	0.0034
Echinococcus multilocularis	transfer RNA-Thr	0.0058	0.004	0.0041
Trichomonas vaginalis	kinesin light chain, putative	0.0074	0.0072	0.0462
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	tyrosine kinase	0.0058	0.004	0.0041
Brugia malayi	Protein kinase domain containing protein	0.0058	0.004	0.0034
Entamoeba histolytica	pleckstrin homology (PH) domain containing protein	0.0074	0.0072	0.0212
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Entamoeba histolytica	hypothetical protein	0.0809	0.1556	1
Trichomonas vaginalis	protein transport protein sec7, putative	0.0074	0.0072	0.0462
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0058	0.004	0.0041
Loa Loa (eye worm)	hypothetical protein	0.0387	0.0703	0.0698
Entamoeba histolytica	cell surface protease gp63, putative	0.017	0.0264	0.1481
Loa Loa (eye worm)	hypothetical protein	0.0387	0.0703	0.0698
Entamoeba histolytica	hypothetical protein	0.017	0.0264	0.1481
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0058	0.004	0.0041
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0094	0.0112	0.0478
Brugia malayi	Variant SH3 domain containing protein	0.0074	0.0072	0.0066
Schistosoma mansoni	zinc finger protein	0.0074	0.0072	0.0059
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0809	0.1556	0.1551
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0074	0.0072	0.0079
Onchocerca volvulus	Protein melted homolog	0.0074	0.0072	0.0187
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Loa Loa (eye worm)	serine/threonine protein kinase	0.0058	0.004	0.0034
Echinococcus multilocularis	regulator of G protein signaling	0.0809	0.1556	0.1855
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	protein transport protein sec7, putative	0.0074	0.0072	0.0462
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Loa Loa (eye worm)	syntrophin-1	0.0074	0.0072	0.0066
Echinococcus granulosus	raf serine:threonine protein kinase	0.0058	0.004	0.0041
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0058	0.004	0.0041
Echinococcus multilocularis	beta 1 syntrophin	0.0074	0.0072	0.0079
Brugia malayi	serine/threonine protein kinase 6	0.008	0.0083	0.0077
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0078	0.008	0.5559
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0072	0.0462
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0058	0.004	0.0255
Schistosoma mansoni	protein kinase	0.0058	0.004	0.0027
Echinococcus granulosus	beta 1 syntrophin	0.0074	0.0072	0.0079
Loa Loa (eye worm)	SRC-1	0.0058	0.004	0.0034
Entamoeba histolytica	hypothetical protein	0.0074	0.0072	0.0212
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0058	0.004	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0058	0.004	0.0255
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0058	0.004	0.0034
Echinococcus multilocularis	tyrosine protein kinase shark	0.0058	0.004	0.0041
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0058	0.004	0.0034
Echinococcus granulosus	Rho GTPase activating protein 24	0.0074	0.0072	0.0079
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0074	0.0072	0.0212
Trichomonas vaginalis	AGC family protein kinase	0.0094	0.0112	0.0721
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0058	0.004	0.0034
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0078	0.008	0.5559
Schistosoma mansoni	tyrosine kinase	0.0058	0.004	0.0027

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1739006

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1509294