TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 459.421 | Formula: C22H20F3N5O3
H donors: 2 H acceptors: 5 LogP: -1.05 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: N[C@H](Cc1cc(F)c(cc1F)F)CC(=O)N1CCn2c(C1)c(nn2)c1ccc(cc1)C(=O)O
InChi: 1S/C22H20F3N5O3/c23-16-10-18(25)17(24)8-14(16)7-15(26)9-20(31)29-5-6-30-19(11-29)21(27-28-30)12-1-3-13(4-2-12)22(32)33/h1-4,8,10,15H,5-7,9,11,26H2,(H,32,33)/t15-/m1/s1
InChiKey: AKGVZAMLOAMAEF-OAHLLOKOSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	hypothetical protein	0.0143	0.024	0.0227
Brugia malayi	Plexin repeat family protein	0.077	0.1651	0.1647
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0067	0.0067	0.5066
Entamoeba histolytica	protein kinase domain containing protein	0.0076	0.0088	0.0408
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0067	0.0067	0.5066
Echinococcus multilocularis	plexin a4	0.0913	0.1974	0.2355
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Echinococcus granulosus	receptor type guanylyl cyclase	0.0048	0.0026	0.0024
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0076	0.0088	0.0099
Brugia malayi	hypothetical protein	0.0726	0.1552	0.1547
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0143	0.024	0.1548
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	TK/ALK protein kinase	0.0312	0.062	0.0615
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Entamoeba histolytica	hypothetical protein	0.0067	0.0067	0.0272
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	uncoordinated protein 104	0.0067	0.0067	0.0062
Echinococcus multilocularis	aurora kinase A	0.0076	0.0088	0.0099
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	protein kinase	0.0076	0.0088	0.0074
Schistosoma mansoni	dynamin	0.0067	0.0067	0.0054
Echinococcus granulosus	dynamin 1	0.0067	0.0067	0.0074
Echinococcus multilocularis	protein kinase	0.0048	0.0026	0.0024
Echinococcus multilocularis	axis inhibition protein axin	0.0726	0.1552	0.185
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.3751	0.8365	1
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0067	0.0067	0.0062
Schistosoma mansoni	regulator of G protein signaling	0.0726	0.1552	0.154
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0048	0.0026	0.0024
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	serine/threonine protein kinase	0.0048	0.0026	0.002
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0048	0.0026	0.0024
Schistosoma mansoni	syntrophin	0.0067	0.0067	0.0054
Echinococcus granulosus	activin receptor type	0.0066	0.0066	0.0072
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Echinococcus multilocularis	tyrosine kinase	0.0048	0.0026	0.0024
Brugia malayi	probable spectrin beta chain	0.0067	0.0067	0.0062
Brugia malayi	plexin A	0.0913	0.1974	0.197
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0085	0.0108	1
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.0085	0.0108	1
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Loa Loa (eye worm)	cytohesin 3	0.0067	0.0067	0.0062
Brugia malayi	hypothetical protein	0.0327	0.0654	0.0649
Loa Loa (eye worm)	hypothetical protein	0.0143	0.024	0.0235
Echinococcus multilocularis	hypothetical protein	0.0327	0.0654	0.0776
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	exocyst complex component 2	0.0143	0.024	0.0281
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Echinococcus multilocularis	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0085	0.0108	1
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0067	0.0067	0.0074
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0048	0.0026	0.0024
Trichomonas vaginalis	conserved hypothetical protein	0.0726	0.1552	1
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0048	0.0026	0.0168
Trichomonas vaginalis	conserved hypothetical protein	0.0726	0.1552	1
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Schistosoma mansoni	serine/threonine protein kinase	0.0048	0.0026	0.0012
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	Pleckstrin y	0.0067	0.0067	0.0074
Brugia malayi	ephrin receptor 1 precursor	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	protein kinase	0.0066	0.0066	0.0053
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0726	0.1552	0.1547
Echinococcus multilocularis	protein kinase	0.0048	0.0026	0.0024
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0048	0.0026	0.0012
Echinococcus granulosus	Pleckstrin y	0.0067	0.0067	0.0074
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0048	0.0026	0.0168
Trypanosoma brucei	protein kinase, putative	0.0066	0.0066	0.4934
Loa Loa (eye worm)	TK/ABL protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0108	0.0102
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0067	0.0067	0.0255
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.0085	0.0108	1
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0066	0.0066	0.0072
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0066	0.0066	0.4934
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0067	0.0067	0.0074
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	kinesin light chain, putative	0.0067	0.0067	0.0435
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Echinococcus granulosus	activated cdc42 kinase 1	0.0048	0.0026	0.0024
Brugia malayi	hypothetical protein	0.0048	0.0026	0.002
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trypanosoma brucei	aurora B kinase	0.0076	0.0088	0.761
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0067	0.0067	0.0255
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Echinococcus multilocularis	rac serine:threonine kinase	0.0085	0.0108	0.0122
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	Probable exocyst complex component Sec5	0.0143	0.024	0.0235
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Toxoplasma gondii	hypothetical protein	0.0067	0.0067	0.5066
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus granulosus	Oxysterol binding protein 11	0.0067	0.0067	0.0074
Loa Loa (eye worm)	hypothetical protein	0.008	0.0097	0.0091
Brugia malayi	serine/threonine-protein kinase 6	0.0076	0.0088	0.0083
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0048	0.0026	0.0024
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0076	0.0088	0.0099
Echinococcus multilocularis	roundabout 2	0.0085	0.0108	0.0122
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	activated cdc42 kinase 1	0.0048	0.0026	0.0024
Schistosoma mansoni	serine/threonine protein kinase	0.3432	0.7646	0.7643
Plasmodium falciparum	oxysterol-binding protein, putative	0.0067	0.0067	0.5066
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0067	0.0067	0.0272
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0048	0.0026	0.0024
Echinococcus multilocularis	expressed protein	0.0726	0.1552	0.185
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.0085	0.0108	0.0695
Schistosoma mansoni	hypothetical protein	0.0067	0.0067	0.0054
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0048	0.0026	0.0024
Echinococcus granulosus	tyrosine protein kinase shark	0.0048	0.0026	0.0024
Schistosoma mansoni	regulator of G protein signaling	0.0726	0.1552	0.154
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0067	0.0067	0.0074
Echinococcus multilocularis	epidermal growth factor receptor	0.0048	0.0026	0.0024
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.3751	0.8365	0.8364
Echinococcus granulosus	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Trichomonas vaginalis	protein transport protein sec7, putative	0.0067	0.0067	0.0435
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0048	0.0026	0.0024
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0048	0.0026	0.0012
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Echinococcus multilocularis	regulator of G protein signaling 7	0.0726	0.1552	0.185
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0067	0.0067	0.5066
Brugia malayi	A-kinase anchor protein 10, precursor	0.0726	0.1552	0.1547
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	hypothetical protein	0.0143	0.024	0.1404
Trichomonas vaginalis	AGC family protein kinase	0.0076	0.0088	0.0569
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0048	0.0026	0.0024
Trichomonas vaginalis	AGC family protein kinase	0.0048	0.0026	0.0168
Loa Loa (eye worm)	AUR protein kinase	0.0076	0.0088	0.0083
Onchocerca volvulus		0.0067	0.0067	0.0255
Echinococcus granulosus	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0067	0.0067	0.0074
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.0085	0.0108	1
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	dynamin 1	0.0067	0.0067	0.0074
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.077	0.1651	0.1647
Schistosoma mansoni	serine/threonine protein kinase	0.3432	0.7646	0.7643
Onchocerca volvulus		0.0327	0.0654	0.3865
Echinococcus multilocularis	insulin receptor	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0327	0.0654	0.0649
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Toxoplasma gondii	AtPH1 family protein	0.0067	0.0067	0.5066
Entamoeba histolytica	hypothetical protein	0.0085	0.0108	0.0536
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Echinococcus granulosus	regulator of G protein signaling 3	0.0726	0.1552	0.185
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus granulosus	oxysterol binding protein 1	0.0067	0.0067	0.0074
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0067	0.0067	0.0074
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Brugia malayi	PXA domain containing protein	0.0726	0.1552	0.1547
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0085	0.0108	1
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Echinococcus granulosus	neuroglian	0.008	0.0097	0.0109
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Brugia malayi	Tyrosine-protein kinase abl-1	0.0048	0.0026	0.002
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0143	0.024	0.1548
Trichomonas vaginalis	protein transport protein sec7, putative	0.0067	0.0067	0.0435
Schistosoma mansoni	hypothetical protein	0.0143	0.024	0.0227
Loa Loa (eye worm)	hypothetical protein	0.0726	0.1552	0.1547
Schistosoma mansoni	goodpasture antigen-binding protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	Immunoglobulin	0.008	0.0097	0.0109
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus multilocularis	activin receptor type	0.0066	0.0066	0.0072
Echinococcus granulosus	transcription factor collier	0.0143	0.024	0.0281
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0726	0.1552	0.185
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0048	0.0026	0.0024
Brugia malayi	regulator of G-protein signaling egl-10	0.0726	0.1552	0.1547
Echinococcus granulosus	defective proboscis extension response	0.008	0.0097	0.0109
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0085	0.0108	1
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Echinococcus granulosus	regulator of G protein signaling 7	0.0726	0.1552	0.185
Echinococcus granulosus	tyrosine kinase	0.0048	0.0026	0.0024
Entamoeba histolytica	hypothetical protein	0.0067	0.0067	0.0272
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Onchocerca volvulus		0.0067	0.0067	0.0255
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.008	0.0097	0.0083
Schistosoma mansoni	vesicular amine transporter	0.0082	0.0103	0.0089
Echinococcus multilocularis	tyrosine kinase	0.0048	0.0026	0.0024
Schistosoma mansoni	ephrin receptor	0.0053	0.0037	0.0023
Echinococcus granulosus	tyrosine kinase	0.0048	0.0026	0.0024
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Onchocerca volvulus	Putative zinc finger protein	0.0067	0.0067	0.0255
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0048	0.0026	0.0024
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Onchocerca volvulus		0.0067	0.0067	0.0255
Entamoeba histolytica	hypothetical protein	0.0143	0.024	0.1404
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Entamoeba histolytica	p21-activated kinase	0.0085	0.0108	0.0536
Schistosoma mansoni	hypothetical protein	0.0443	0.0915	0.0902
Echinococcus granulosus	protein tyrosine kinase	0.0048	0.0026	0.0024
Entamoeba histolytica	protein kinase domain containing protein	0.0192	0.0349	0.2115
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0076	0.0088	0.0408
Brugia malayi	integrin-linked kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.2706	0.6011	0.7184
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0076	0.0088	0.0408
Loa Loa (eye worm)	hypothetical protein	0.0726	0.1552	0.1547
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	Plekhf2 protein	0.0067	0.0067	0.0062
Entamoeba histolytica	PH domain containing protein	0.0067	0.0067	0.0272
Echinococcus granulosus	regulator of G protein signaling 7	0.0726	0.1552	0.185
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0048	0.0026	0.0012
Brugia malayi	Sema domain containing protein	0.0327	0.0654	0.0649
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0726	0.1552	0.185
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0048	0.0026	0.0168
Trichomonas vaginalis	conserved hypothetical protein	0.0726	0.1552	1
Schistosoma mansoni	hypothetical protein	0.0327	0.0654	0.0641
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0108	0.0102
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Onchocerca volvulus	Protein melted homolog	0.0067	0.0067	0.0255
Entamoeba histolytica	hypothetical protein	0.0143	0.024	0.1404
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0067	0.0067	0.0272
Schistosoma mansoni	fibrocystin l	0.0143	0.024	0.0227
Echinococcus granulosus	aurora kinase A	0.0076	0.0088	0.0099
Echinococcus granulosus	natriuretic peptide receptor 1	0.0048	0.0026	0.0024
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0085	0.0108	0.0536
Echinococcus granulosus	calcium dependent secretion activator 1	0.0067	0.0067	0.0074
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0048	0.0026	0.0024
Schistosoma mansoni	cell adhesion molecule	0.0085	0.0108	0.0094
Echinococcus granulosus	semaphorin 1A	0.0327	0.0654	0.0776
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0048	0.0026	0.002
Brugia malayi	Pleckstrin Homology Domain	0.0067	0.0067	0.0062
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0066	0.0066	0.4934
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0085	0.0108	0.0536
Loa Loa (eye worm)	hypothetical protein	0.0726	0.1552	0.1547
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0108	0.0102
Echinococcus granulosus	expressed protein	0.0726	0.1552	0.185
Loa Loa (eye worm)	TK/FAK protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0048	0.0026	0.0012
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Leishmania major	hypothetical protein, conserved	0.0067	0.0067	0.5066
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0048	0.0026	0.0012
Trypanosoma cruzi	PH domain containing protein, putative	0.0067	0.0067	0.5066
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0067	0.0067	0.0435
Entamoeba histolytica	hypothetical protein	0.0085	0.0108	0.0536
Entamoeba histolytica	protein kinase domain containing protein	0.0066	0.0066	0.0265
Loa Loa (eye worm)	TK/INSR protein kinase	0.0048	0.0026	0.002
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Echinococcus multilocularis	oxysterol binding protein 3	0.0067	0.0067	0.0074
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	centaurin alpha	0.0067	0.0067	0.0054
Echinococcus multilocularis	Oxysterol binding protein 11	0.0067	0.0067	0.0074
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Giardia lamblia	Aurora kinase	0.0076	0.0088	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.0048	0.0026	0.0024
Schistosoma mansoni	plexin	0.0443	0.0915	0.0902
Brugia malayi	Cadps2 protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.3751	0.8365	0.8364
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	hypothetical protein	0.0067	0.0067	0.0054
Entamoeba histolytica	pleckstrin homology (PH) domain containing protein	0.0067	0.0067	0.0272
Schistosoma mansoni	serine/threonine protein kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0066	0.0066	0.4934
Echinococcus granulosus	integrin linked protein kinase	0.0048	0.0026	0.0024
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0067	0.0067	0.0074
Echinococcus granulosus	plexin a4	0.0913	0.1974	0.2355
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0048	0.0026	0.0024
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus granulosus	semaphorin 5B	0.0327	0.0654	0.0776
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Entamoeba histolytica	hypothetical protein	0.0726	0.1552	1
Echinococcus granulosus	pleckstrin y domain containing family A	0.0067	0.0067	0.0074
Trichomonas vaginalis	centaurin beta, putative	0.0067	0.0067	0.0435
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0726	0.1552	0.185
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0048	0.0026	0.0024
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0067	0.0067	0.5066
Loa Loa (eye worm)	RGS-3 protein	0.0726	0.1552	0.1547
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Brugia malayi	Oxysterol-binding protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	PXA domain-containing protein	0.0726	0.1552	0.1547
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	PH domain containing protein	0.0067	0.0067	0.0272
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0066	0.0066	0.4934
Schistosoma mansoni	zinc finger protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0143	0.024	0.1548
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	pdz domain containing protein	0.0067	0.0067	0.0074
Leishmania major	serine/threonine-protein kinase a, putative	0.0085	0.0108	1
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.3751	0.8365	0.8364
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	Variant SH3 domain containing protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	beta adrenergic receptor kinase	0.3432	0.7646	0.914
Loa Loa (eye worm)	TK/ROR protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0048	0.0026	0.0024
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0067	0.0067	0.0054
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0067	0.0067	0.0074
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Schistosoma mansoni	regulator of G protein signaling	0.0726	0.1552	0.154
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0067	0.0067	0.0074
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Brugia malayi	SH2 domain containing protein	0.0048	0.0026	0.002
Echinococcus granulosus	raf serine:threonine protein kinase	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0143	0.024	0.0235
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	hypothetical protein	0.0067	0.0067	0.0435
Schistosoma mansoni	regulator of G protein signaling	0.0726	0.1552	0.154
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0067	0.0067	0.0074
Schistosoma mansoni	hypothetical protein	0.0048	0.0026	0.0012
Echinococcus granulosus	tyrosine kinase	0.0048	0.0026	0.0024
Echinococcus multilocularis	regulator of G protein signaling 3	0.0726	0.1552	0.185
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0048	0.0026	0.0024
Brugia malayi	Furin-like cysteine rich region family protein	0.0048	0.0026	0.002
Echinococcus granulosus	axis inhibition protein axin	0.0726	0.1552	0.185
Trichomonas vaginalis	AGC family protein kinase	0.0076	0.0088	0.0569
Echinococcus multilocularis	tyrosine protein kinase shark	0.0048	0.0026	0.0024
Echinococcus granulosus	cytohesin 1	0.0067	0.0067	0.0074
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0067	0.0067	0.0062
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0048	0.0026	0.0024
Brugia malayi	Tyrosine-protein kinase PR2	0.0048	0.0026	0.002
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0085	0.0108	0.0102
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Schistosoma mansoni	nephrin	0.0085	0.0108	0.0094
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0048	0.0026	0.0024
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0085	0.0108	0.0102
Echinococcus granulosus	GRB2 associated binding protein 3	0.0067	0.0067	0.0074
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Leishmania major	folate/biopterin transporter, putative	0.0085	0.0108	1
Trichomonas vaginalis	centaurin/arf, putative	0.0067	0.0067	0.0435
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Loa Loa (eye worm)	sema domain-containing protein	0.0327	0.0654	0.0649
Schistosoma mansoni	vav2	0.0067	0.0067	0.0054
Schistosoma mansoni	growth factor receptor-bound protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0048	0.0026	0.0024
Loa Loa (eye worm)	plexin A	0.0913	0.1974	0.197
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0053	0.0037	0.0037
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0048	0.0026	0.0024
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Leishmania major	hypothetical protein, conserved	0.0067	0.0067	0.5066
Brugia malayi	Fibronectin type III domain containing protein	0.0085	0.0108	0.0102
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0067	0.0067	0.5066
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Onchocerca volvulus		0.0067	0.0067	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	regulator of G protein signaling 3	0.0726	0.1552	0.185
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0726	0.1552	0.1547
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0048	0.0026	0.002
Echinococcus granulosus	oxysterol binding protein 9	0.0067	0.0067	0.0074
Echinococcus multilocularis	oxysterol binding protein 9	0.0067	0.0067	0.0074
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0048	0.0026	0.0024
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Brugia malayi	Receptor family ligand binding region containing protein	0.0048	0.0026	0.002
Schistosoma mansoni	protein kinase	0.0066	0.0066	0.0053
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0143	0.024	0.1548
Trypanosoma brucei	protein kinase, putative	0.0085	0.0108	1
Echinococcus granulosus	regulator of G protein signaling 3	0.0726	0.1552	0.185
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0048	0.0026	0.0024
Schistosoma mansoni	axis inhibition protein axin	0.0726	0.1552	0.154
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Echinococcus multilocularis	Pleckstrin y	0.0067	0.0067	0.0074
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0128	0.0206	0.02
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	hypothetical protein, conserved	0.0067	0.0067	0.0272
Brugia malayi	Protein kinase domain containing protein	0.0312	0.062	0.0615
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0143	0.024	0.1548
Schistosoma mansoni	protein kinase	0.0066	0.0066	0.0053
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0067	0.0067	0.0074
Entamoeba histolytica	hypothetical protein	0.0726	0.1552	1
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Echinococcus granulosus	ephrin type A receptor 4 A	0.0048	0.0026	0.0024
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0048	0.0026	0.0024
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0048	0.0026	0.002
Brugia malayi	SH2 domain containing protein	0.0048	0.0026	0.002
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0067	0.0067	0.0074
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0067	0.0067	0.5066
Onchocerca volvulus		0.0067	0.0067	0.0255
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0726	0.1552	0.1547
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.0085	0.0108	1
Schistosoma mansoni	serine/threonine-protein kinase	0.0085	0.0108	0.0094
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0048	0.0026	0.0024
Onchocerca volvulus		0.0067	0.0067	0.0255
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	syntrophin-1	0.0067	0.0067	0.0062
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.3432	0.7646	0.7645
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0048	0.0026	0.0024
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	hypothetical protein	0.0327	0.0654	0.0649
Loa Loa (eye worm)	TK/EPH protein kinase	0.0048	0.0026	0.002
Trypanosoma cruzi	NIMA-related kinase, putative	0.0085	0.0108	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0066	0.0066	0.0072
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0048	0.0026	0.0024
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	hypothetical protein	0.0067	0.0067	0.0272
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trypanosoma cruzi	PH domain containing protein, putative	0.0067	0.0067	0.5066
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0048	0.0026	0.0024
Plasmodium falciparum	PH domain-containing protein, putative	0.0067	0.0067	0.5066
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0726	0.1552	0.154
Schistosoma mansoni	hypothetical protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	G protein coupled receptor kinase 1	0.2706	0.6011	0.7184
Schistosoma mansoni	ephrin receptor	0.0048	0.0026	0.0012
Echinococcus multilocularis	beta 1 syntrophin	0.0067	0.0067	0.0074
Brugia malayi	Cytohesin 3	0.0067	0.0067	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trypanosoma cruzi	NIMA-related kinase, putative	0.0085	0.0108	1
Loa Loa (eye worm)	hypothetical protein	0.0327	0.0654	0.0649
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0067	0.0067	0.0435
Brugia malayi	Oxysterol binding protein	0.0067	0.0067	0.0062
Plasmodium vivax	PH domain containing protein	0.0067	0.0067	0.5066
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Plekhf2 protein	0.0067	0.0067	0.0062
Leishmania major	protein kinase, putative	0.0066	0.0066	0.4934
Echinococcus multilocularis	semaphorin 5B	0.0327	0.0654	0.0776
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0067	0.0067	0.0074
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0048	0.0026	0.0024
Schistosoma mansoni	zinc finger protein	0.0067	0.0067	0.0054
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	oxysterol binding protein	0.0067	0.0067	0.0062
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0085	0.0108	1
Brugia malayi	Sema domain containing protein	0.0327	0.0654	0.0649
Echinococcus multilocularis	cytohesin 1	0.0067	0.0067	0.0074
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0726	0.1552	0.1547
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0726	0.1552	0.154
Loa Loa (eye worm)	AUR protein kinase	0.0076	0.0088	0.0083
Echinococcus multilocularis	actin binding protein anillin	0.0067	0.0067	0.0074
Brugia malayi	Protein kinase domain containing protein	0.0085	0.0108	0.0102
Echinococcus multilocularis	regulator of G protein signaling	0.0726	0.1552	0.185
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.3751	0.8365	1
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.0085	0.0108	1
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	AGC family protein kinase	0.0076	0.0088	0.0569
Echinococcus multilocularis	activated cdc42 kinase 1	0.0048	0.0026	0.0024
Schistosoma mansoni	protein tyrosine kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	regulator of G protein signaling	0.0726	0.1552	0.154
Loa Loa (eye worm)	PH domain-containing protein	0.0067	0.0067	0.0062
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Entamoeba histolytica	PH domain containing protein	0.0067	0.0067	0.0272
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Onchocerca volvulus	outspread protein homolog	0.0067	0.0067	0.0255
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0048	0.0026	0.0168
Entamoeba histolytica	tyrosin kinase, putative	0.0192	0.0349	0.2115
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0048	0.0026	0.0024
Leishmania major	protein kinase, putative	0.0085	0.0108	1
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0048	0.0026	0.0024
Entamoeba histolytica	hypothetical protein	0.0067	0.0067	0.0272
Brugia malayi	Raf kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	SRC-1	0.0048	0.0026	0.002
Entamoeba histolytica	protein kinase , putative	0.0076	0.0088	0.0408
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Schistosoma mansoni	myotubularin-related protein	0.0067	0.0067	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0048	0.0026	0.002
Echinococcus multilocularis	heat shock protein 70	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0327	0.0654	0.0649
Brugia malayi	regulator of G-protein signaling rgs-7	0.0726	0.1552	0.1547
Trichomonas vaginalis	CAMK family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	tyrosine protein kinase	0.0048	0.0026	0.0012
Echinococcus granulosus	Pleckstrin y	0.0067	0.0067	0.0074
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	pdz domain containing protein	0.0067	0.0067	0.0074
Entamoeba histolytica	cell surface protease gp63, putative	0.0143	0.024	0.1404
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0053	0.0037	0.0037
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0085	0.0108	1
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Echinococcus multilocularis	axis inhibition protein axin	0.0726	0.1552	0.185
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Trypanosoma cruzi	Protein kinase B	0.0085	0.0108	1
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0048	0.0026	0.0012
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0067	0.0067	0.0074
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0067	0.0067	0.5066
Loa Loa (eye worm)	hypothetical protein	0.0143	0.024	0.0235
Brugia malayi	serine/threonine protein kinase 6	0.0076	0.0088	0.0083
Loa Loa (eye worm)	hypothetical protein	0.0232	0.044	0.0435
Echinococcus granulosus	epidermal growth factor receptor	0.0048	0.0026	0.0024
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.0085	0.0108	1
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0048	0.0026	0.0024
Echinococcus multilocularis	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Trypanosoma cruzi	aurora B kinase, putative	0.0076	0.0088	0.761
Echinococcus granulosus	Immunoglobulin	0.008	0.0097	0.0109
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0048	0.0026	0.0024
Echinococcus multilocularis	integrin linked protein kinase	0.0048	0.0026	0.0024
Trypanosoma cruzi	PH domain containing protein, putative	0.0067	0.0067	0.5066
Schistosoma mansoni	oxysterol-binding protein 1	0.0067	0.0067	0.0054
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0085	0.0108	1
Loa Loa (eye worm)	hypothetical protein	0.0327	0.0654	0.0649
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0067	0.0067	0.0074
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Loa Loa (eye worm)	TK/Met protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Brugia malayi	Dynamin	0.0067	0.0067	0.0062
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0067	0.0067	0.0074
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0067	0.0067	0.0074
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0067	0.0067	0.5066
Onchocerca volvulus		0.077	0.1651	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Toxoplasma gondii	hypothetical protein	0.0067	0.0067	0.5066
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.0085	0.0108	0.0695
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Schistosoma mansoni	serine/threonine RGC	0.0048	0.0026	0.0012
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0066	0.0066	0.0072
Echinococcus granulosus	Rho GTPase activating protein 24	0.0067	0.0067	0.0074
Plasmodium vivax	hypothetical protein, conserved	0.0067	0.0067	0.5066
Loa Loa (eye worm)	hypothetical protein	0.008	0.0097	0.0091
Trichomonas vaginalis	protein kinase atn1, putative	0.0048	0.0026	0.0168
Schistosoma mansoni	oxysterol-binding protein 1	0.0067	0.0067	0.0054
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0048	0.0026	0.0012
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0048	0.0026	0.0024
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0048	0.0026	0.0024
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0067	0.0067	0.0435
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	TK family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.008	0.0097	0.0109
Echinococcus granulosus	axis inhibition protein axin	0.0726	0.1552	0.185
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Brugia malayi	Syntrophin-1	0.0067	0.0067	0.0062
Echinococcus multilocularis	regulator of G protein signaling 7	0.0726	0.1552	0.185
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Schistosoma mansoni	semaphorin 5-related	0.0327	0.0654	0.0641
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0048	0.0026	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	neuroglian	0.008	0.0097	0.0109
Brugia malayi	hypothetical protein	0.0048	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Echinococcus multilocularis	Immunoglobulin	0.008	0.0097	0.0109
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.0085	0.0108	1
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Echinococcus granulosus	tyrosine protein kinase Blk	0.0048	0.0026	0.0024
Echinococcus granulosus	beta 1 syntrophin	0.0067	0.0067	0.0074
Echinococcus multilocularis	oxysterol binding protein 1	0.0067	0.0067	0.0074
Brugia malayi	SRC-1	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK/ACK protein kinase	0.0048	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0048	0.0026	0.0024
Echinococcus multilocularis	Pleckstrin y	0.0067	0.0067	0.0074
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0067	0.0067	0.5066
Entamoeba histolytica	protein kinase, putative	0.0076	0.0088	0.0408
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0067	0.0067	0.0435
Schistosoma mansoni	dynamin	0.0067	0.0067	0.0054
Trichomonas vaginalis	centaurin alpha, putative	0.0067	0.0067	0.0435
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.008	0.0097	0.0083
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0067	0.0067	0.0074
Echinococcus granulosus	Pleckstrin y	0.0067	0.0067	0.0074
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Toxoplasma gondii	Oxysterol-binding protein	0.0067	0.0067	0.5066
Echinococcus granulosus	tyrosine protein kinase	0.0048	0.0026	0.0024
Echinococcus granulosus	oxysterol binding protein 3	0.0067	0.0067	0.0074
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Brugia malayi	hypothetical protein	0.0085	0.0108	0.0102
Loa Loa (eye worm)	hypothetical protein	0.008	0.0097	0.0091
Brugia malayi	hypothetical protein	0.0726	0.1552	0.1547
Brugia malayi	PXA domain containing protein	0.0726	0.1552	0.1547
Echinococcus multilocularis	transcription factor collier	0.0143	0.024	0.0281
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0067	0.0067	0.0062
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0048	0.0026	0.0024
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0048	0.0026	0.0024
Brugia malayi	serine/threonine kinase 12	0.0076	0.0088	0.0083
Brugia malayi	MAX-1A	0.0067	0.0067	0.0062
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Brugia malayi	Guanylyl cyclase protein 23	0.0048	0.0026	0.002
Schistosoma mansoni	axis inhibition protein axin	0.0726	0.1552	0.154
Leishmania major	protein kinase, putative	0.0085	0.0108	1
Brugia malayi	DNA-binding protein LAG-1	0.0143	0.024	0.0235
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0726	0.1552	0.154
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0327	0.0654	0.0649
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0048	0.0026	0.0024
Brugia malayi	IPT/TIG domain containing protein	0.0143	0.024	0.0235
Loa Loa (eye worm)	hypothetical protein	0.008	0.0097	0.0091
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Onchocerca volvulus		0.0067	0.0067	0.0255
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0067	0.0067	0.0272
Trypanosoma cruzi	hypothetical protein	0.0067	0.0067	0.5066
Loa Loa (eye worm)	sema domain-containing protein	0.0327	0.0654	0.0649
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0067	0.0067	0.0074
Echinococcus multilocularis	myotubularin protein 13	0.0067	0.0067	0.0074
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Trichomonas vaginalis	conserved hypothetical protein	0.0726	0.1552	1
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0067	0.0067	0.0062
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0067	0.0067	0.0272
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.008	0.0097	0.0091
Trichomonas vaginalis	STE family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Echinococcus multilocularis	transfer RNA-Thr	0.0048	0.0026	0.0024
Trichomonas vaginalis	alpha chimerin, putative	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0067	0.0067	0.0272
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0067	0.0067	0.0074
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Echinococcus multilocularis	protein tyrosine kinase	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0067	0.0067	0.0074
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0327	0.0654	0.0649
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	TBC domain containing protein	0.0067	0.0067	0.0062
Echinococcus multilocularis	c src tyrosine kinase	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0067	0.0067	0.0054
Echinococcus multilocularis	exocyst complex component 2	0.0143	0.024	0.0281
Echinococcus multilocularis	FL cytokine receptor	0.0048	0.0026	0.0024
Brugia malayi	protein-tyrosine kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK/DDR protein kinase	0.0048	0.0026	0.002
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	serine/threonine protein kinase	0.0048	0.0026	0.0012
Toxoplasma gondii	protein kinase domain-containing protein	0.0085	0.0108	1
Schistosoma mansoni	hypothetical protein	0.0327	0.0654	0.0641
Trichomonas vaginalis	conserved hypothetical protein	0.0726	0.1552	1
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0048	0.0026	0.0024
Echinococcus granulosus	epidermal growth factor receptor	0.0048	0.0026	0.0024
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	centaurin/arf, putative	0.0067	0.0067	0.0435
Schistosoma mansoni	hypothetical protein	0.0067	0.0067	0.0054
Echinococcus granulosus	serine/threonine protein kinase	0.0085	0.0108	0.0122
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0085	0.0108	0.0536
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Echinococcus granulosus	roundabout 2	0.0085	0.0108	0.0122
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0085	0.0108	0.0536
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	Dynamin	0.0067	0.0067	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Echinococcus granulosus	Regulator of G protein signaling 20	0.0726	0.1552	0.185
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Loa Loa (eye worm)	hypothetical protein	0.0143	0.024	0.0235
Toxoplasma gondii	aurora kinase	0.0076	0.0088	0.761
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Trichomonas vaginalis	centaurin gamma, putative	0.0067	0.0067	0.0435
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Echinococcus multilocularis	epidermal growth factor receptor	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Loa Loa (eye worm)	hypothetical protein	0.008	0.0097	0.0091
Schistosoma mansoni	hypothetical protein	0.0067	0.0067	0.0054
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0085	0.0108	1
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0048	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase csk	0.0048	0.0026	0.0024
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Schistosoma mansoni	plexin	0.077	0.1651	0.164
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0048	0.0026	0.002
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	AUR protein kinase	0.0076	0.0088	0.0083
Echinococcus granulosus	twitchin	0.0098	0.0137	0.0158
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK/CSK protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0048	0.0026	0.002
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0085	0.0108	1
Entamoeba histolytica	hypothetical protein	0.0143	0.024	0.1404
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0048	0.0026	0.002
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0085	0.0108	1
Trypanosoma cruzi	PH domain containing protein, putative	0.0067	0.0067	0.5066
Schistosoma mansoni	protein kinase	0.0048	0.0026	0.0012
Echinococcus multilocularis	tyrosine protein kinase	0.0048	0.0026	0.0024
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0067	0.0067	0.0074
Entamoeba histolytica	hypothetical protein	0.0067	0.0067	0.0272
Brugia malayi	C-terminal src kinase protein 1	0.0048	0.0026	0.002
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0076	0.0088	0.761
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0085	0.0108	0.0536
Schistosoma mansoni	serine/threonine-protein kinase	0.0085	0.0108	0.0094
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0048	0.0026	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Echinococcus granulosus	protein kinase	0.0048	0.0026	0.0024
Trichomonas vaginalis	conserved hypothetical protein	0.0726	0.1552	1
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0067	0.0067	0.0435
Echinococcus granulosus	kinase suppressor of Ras 1	0.0048	0.0026	0.0024
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0048	0.0026	0.0024
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Echinococcus granulosus	beta-adrenergic receptor kinase	0.3432	0.7646	0.914
Trichomonas vaginalis	conserved hypothetical protein	0.0143	0.024	0.1548
Loa Loa (eye worm)	rho-GTPase-activating	0.0067	0.0067	0.0062
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0067	0.0067	0.0062
Brugia malayi	hypothetical protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0026	0.0168
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0067	0.0435
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Trypanosoma brucei	PH domain containing protein, putative	0.0067	0.0067	0.5066
Echinococcus granulosus	myotubularin protein 13	0.0067	0.0067	0.0074
Echinococcus granulosus	tyrosine protein kinase Srms	0.0048	0.0026	0.0024
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0067	0.0067	0.0074
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.0085	0.0108	1
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0067	0.0067	0.0272
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0048	0.0026	0.002
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0048	0.0026	0.002
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	serine/threonine protein kinase	0.0076	0.0088	0.0074
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0085	0.0108	0.0536
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0048	0.0026	0.0024
Echinococcus granulosus	tyrosine protein kinase pr2	0.0048	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	PH domain containing protein	0.0067	0.0067	0.0062
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0726	0.1552	1
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0076	0.0088	0.761
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Plasmodium falciparum	protein kinase, putative	0.0066	0.0066	0.4934
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0726	0.1552	0.1547
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0067	0.0067	0.0272
Schistosoma mansoni	goodpasture antigen-binding protein	0.0067	0.0067	0.0054
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0067	0.0067	0.0435
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0067	0.0067	0.5066
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Loa Loa (eye worm)	TK/FER protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0076	0.0088	0.0408
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Entamoeba histolytica	protein kinase, putative	0.0076	0.0088	0.0408
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.0085	0.0108	1
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0067	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0726	0.1552	0.1547
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0048	0.0026	0.0024
Brugia malayi	Uncoordinated protein 104	0.0067	0.0067	0.0062
Schistosoma mansoni	tyrosine kinase	0.0048	0.0026	0.0012
Schistosoma mansoni	serine/threonine protein kinase	0.0048	0.0026	0.0012
Trichomonas vaginalis	AGC family protein kinase	0.0085	0.0108	0.0695
Loa Loa (eye worm)	TK/RYK protein kinase	0.0048	0.0026	0.002
Loa Loa (eye worm)	hypothetical protein	0.0443	0.0915	0.0909
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0026	0.002
Echinococcus granulosus	insulin receptor	0.0048	0.0026	0.0024
Brugia malayi	hypothetical protein	0.0048	0.0026	0.002
Entamoeba histolytica	protein kinase, putative	0.0085	0.0108	0.0536
Echinococcus granulosus	c src tyrosine kinase	0.0048	0.0026	0.0024
Echinococcus granulosus	DCC interacting protein 13 beta	0.0067	0.0067	0.0074
Trichomonas vaginalis	AGC family protein kinase	0.0076	0.0088	0.0569
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0048	0.0026	0.0024
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0048	0.0026	0.0024
Schistosoma mansoni	z-protein (S1r protein)	0.0726	0.1552	0.154
Leishmania major	protein kinase, putative	0.0076	0.0088	0.761
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.008	0.0097	0.0109
Loa Loa (eye worm)	TK protein kinase	0.0048	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Brugia malayi	Variant SH3 domain containing protein	0.0067	0.0067	0.0062
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0026	0.002
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0128	0.0206	0.02
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Trichomonas vaginalis	TKL family protein kinase	0.0048	0.0026	0.0168
Schistosoma mansoni	rho gtpase activating protein	0.0067	0.0067	0.0054
Entamoeba histolytica	hypothetical protein	0.0726	0.1552	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1739482

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1509296