TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 244.289 | Formula: C14H16N2O2
H donors: 1 H acceptors: 2 LogP: 0.86 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: O=C1N[C@@H]2[C@@H](C1)CN(CC2)C(=O)c1ccccc1
InChi: 1S/C14H16N2O2/c17-13-8-11-9-16(7-6-12(11)15-13)14(18)10-4-2-1-3-5-10/h1-5,11-12H,6-9H2,(H,15,17)/t11-,12-/m0/s1
InChiKey: AHASWSHYSJCVFY-RYUDHWBXSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Brugia malayi	IPT/TIG domain containing protein	0.0124	0.0291	0.0283
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0043	0.0022	0.0142
Schistosoma mansoni	ephrin receptor	0.0043	0.0022	0.0001
Loa Loa (eye worm)	plexin A	0.0789	0.2496	0.2489
Schistosoma mansoni	z-protein (S1r protein)	0.0495	0.1521	0.1503
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0058	0.0071	0.0332
Schistosoma mansoni	hypothetical protein	0.0045	0.003	0.001
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0043	0.0022	0.0013
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0043	0.0022	0.0016
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	centaurin beta, putative	0.0045	0.003	0.0199
Schistosoma mansoni	serine/threonine RGC	0.0043	0.0022	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.2558	0.8359	0.8358
Echinococcus multilocularis	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Entamoeba histolytica	hypothetical protein	0.0124	0.0291	0.1801
Trypanosoma cruzi	Protein kinase B	0.0058	0.0071	0.5021
Brugia malayi	Plexin repeat family protein	0.0665	0.2084	0.2077
Echinococcus granulosus	calcium dependent secretion activator 1	0.0045	0.003	0.0026
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0043	0.0022	0.0016
Brugia malayi	regulator of G-protein signaling egl-10	0.0495	0.1521	0.1513
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Loa Loa (eye worm)	AUR protein kinase	0.0073	0.0121	0.0112
Brugia malayi	DNA-binding protein LAG-1	0.0124	0.0291	0.0283
Loa Loa (eye worm)	AUR protein kinase	0.0073	0.0121	0.0112
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0045	0.003	0.001
Schistosoma mansoni	axis inhibition protein axin	0.0495	0.1521	0.1503
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Entamoeba histolytica	hypothetical protein	0.0045	0.003	0.0058
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0045	0.003	0.0022
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0045	0.003	0.0026
Echinococcus granulosus	tyrosine protein kinase Blk	0.0043	0.0022	0.0016
Brugia malayi	hypothetical protein	0.0284	0.082	0.0812
Echinococcus granulosus	protein tyrosine kinase	0.0043	0.0022	0.0016
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Brugia malayi	Sema domain containing protein	0.0284	0.082	0.0812
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0058	0.0071	0.5021
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0058	0.0071	0.0063
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0495	0.1521	0.1513
Echinococcus multilocularis	Pleckstrin y	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0045	0.003	0.0875
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0078	0.014	0.012
Schistosoma mansoni	dynamin	0.0045	0.003	0.001
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Loa Loa (eye worm)	hypothetical protein	0.0078	0.014	0.0131
Brugia malayi	Raf kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	RGS-3 protein	0.0495	0.1521	0.1513
Entamoeba histolytica	hypothetical protein	0.0124	0.0291	0.1801
Schistosoma mansoni	syntrophin	0.0045	0.003	0.001
Entamoeba histolytica	hypothetical protein	0.0058	0.0071	0.0332
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0043	0.0022	0.0001
Echinococcus granulosus	serine/threonine protein kinase	0.0058	0.0071	0.0075
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	TK/DDR protein kinase	0.0043	0.0022	0.0013
Brugia malayi	PXA domain containing protein	0.0495	0.1521	0.1513
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0045	0.003	0.0026
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	Immunoglobulin	0.0078	0.014	0.0157
Schistosoma mansoni	serine/threonine protein kinase	0.0043	0.0022	0.0001
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK/RYK protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0124	0.0291	0.1917
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	Oxysterol binding protein 11	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	integrin linked protein kinase	0.0043	0.0022	0.0016
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	tyrosine kinase	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0124	0.0291	0.0283
Schistosoma mansoni	serine/threonine-protein kinase	0.0058	0.0071	0.0051
Trichomonas vaginalis	AGC family protein kinase	0.0073	0.0121	0.0794
Loa Loa (eye worm)	hypothetical protein	0.0495	0.1521	0.1513
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0043	0.0022	0.0142
Trichomonas vaginalis	hypothetical protein	0.0045	0.003	0.0199
Plasmodium falciparum	oxysterol-binding protein, putative	0.0045	0.003	0.0875
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0043	0.0022	0.0016
Schistosoma mansoni	hypothetical protein	0.0045	0.003	0.001
Trypanosoma cruzi	NIMA-related kinase, putative	0.0058	0.0071	0.5021
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0045	0.003	0.0026
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0043	0.0022	0.0016
Echinococcus granulosus	Regulator of G protein signaling 20	0.0495	0.1521	0.1811
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	regulator of G protein signaling 3	0.0495	0.1521	0.1811
Echinococcus multilocularis	semaphorin 5B	0.0284	0.082	0.0971
Schistosoma mansoni	growth factor receptor-bound protein	0.0045	0.003	0.001
Echinococcus granulosus	cytohesin 1	0.0045	0.003	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Brugia malayi	hypothetical protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0048	0.0037	0.0035
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Echinococcus multilocularis	regulator of G protein signaling 3	0.0495	0.1521	0.1811
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.0058	0.0071	0.5021
Echinococcus granulosus	GRB2 associated binding protein 3	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Entamoeba histolytica	PH domain containing protein	0.0045	0.003	0.0058
Echinococcus granulosus	oxysterol binding protein 1	0.0045	0.003	0.0026
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trichomonas vaginalis	AGC family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	pdz domain containing protein	0.0045	0.003	0.0026
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0045	0.003	0.0058
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0043	0.0022	0.0016
Echinococcus multilocularis	insulin receptor	0.0043	0.0022	0.0016
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.2558	0.8359	1
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0045	0.003	0.0199
Echinococcus granulosus	semaphorin 5B	0.0284	0.082	0.0971
Echinococcus multilocularis	cytohesin 1	0.0045	0.003	0.0026
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0045	0.003	0.0058
Brugia malayi	Probable exocyst complex component Sec5	0.0124	0.0291	0.0283
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0043	0.0022	0.0016
Echinococcus multilocularis	regulator of G protein signaling 7	0.0495	0.1521	0.1811
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0495	0.1521	0.1513
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0045	0.003	0.0022
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Onchocerca volvulus	Protein melted homolog	0.0045	0.003	0.0042
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Toxoplasma gondii	aurora kinase	0.0073	0.0121	1
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	Pleckstrin y	0.0045	0.003	0.0026
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0043	0.0022	0.0001
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0045	0.003	0.0026
Loa Loa (eye worm)	TK/FAK protein kinase	0.0043	0.0022	0.0013
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0073	0.0121	0.0662
Brugia malayi	MAX-1A	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0124	0.0291	0.0283
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0055	0.0063	0.0065
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	serine/threonine protein kinase 6	0.0073	0.0121	0.0112
Plasmodium falciparum	PH domain-containing protein, putative	0.0045	0.003	0.0875
Echinococcus multilocularis	tyrosine protein kinase shark	0.0043	0.0022	0.0016
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Entamoeba histolytica	protein kinase, putative	0.0073	0.0121	0.0662
Plasmodium vivax	PH domain containing protein	0.0045	0.003	0.0875
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0045	0.003	0.001
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	protein kinase atn1, putative	0.0043	0.0022	0.0142
Schistosoma mansoni	hypothetical protein	0.0381	0.1144	0.1126
Loa Loa (eye worm)	hypothetical protein	0.0124	0.0291	0.0283
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	plexin a4	0.0789	0.2496	0.2979
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0045	0.003	0.0199
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0495	0.1521	0.1513
Echinococcus multilocularis	oxysterol binding protein 3	0.0045	0.003	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Brugia malayi	regulator of G-protein signaling rgs-7	0.0495	0.1521	0.1513
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0043	0.0022	0.0016
Schistosoma mansoni	vesicular amine transporter	0.0081	0.0148	0.0128
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Leishmania major	folate/biopterin transporter, putative	0.0058	0.0071	0.5021
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0043	0.0022	0.0013
Brugia malayi	Oxysterol-binding protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trichomonas vaginalis	protein transport protein sec7, putative	0.0045	0.003	0.0199
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0045	0.003	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0043	0.0022	0.0016
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	nephrin	0.0083	0.0156	0.0136
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	Guanylyl cyclase protein 23	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	tyrosine kinase	0.0043	0.0022	0.0016
Echinococcus granulosus	semaphorin 1A	0.0284	0.082	0.0971
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0045	0.003	0.0875
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0073	0.0121	0.0134
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Echinococcus multilocularis	FL cytokine receptor	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK/Met protein kinase	0.0043	0.0022	0.0013
Echinococcus granulosus	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0045	0.003	0.0026
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Trichomonas vaginalis	TK family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	sema domain-containing protein	0.0284	0.082	0.0812
Loa Loa (eye worm)	PXA domain-containing protein	0.0495	0.1521	0.1513
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Schistosoma mansoni	zinc finger protein	0.0045	0.003	0.001
Brugia malayi	TBC domain containing protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	hypothetical protein	0.0043	0.0022	0.0001
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Onchocerca volvulus		0.0045	0.003	0.0042
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0045	0.003	0.0875
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0078	0.014	0.0157
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0083	0.0156	0.0147
Echinococcus granulosus	activin receptor type	0.0055	0.0063	0.0065
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0045	0.003	0.0199
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0045	0.003	0.0875
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Schistosoma mansoni	cell adhesion molecule	0.0083	0.0156	0.0136
Echinococcus granulosus	aurora kinase A	0.0073	0.0121	0.0134
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0045	0.003	0.0026
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0381	0.1144	0.1137
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0495	0.1521	1
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Echinococcus granulosus	epidermal growth factor receptor	0.0043	0.0022	0.0016
Entamoeba histolytica	pleckstrin homology (PH) domain containing protein	0.0045	0.003	0.0058
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0058	0.0071	0.0332
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0045	0.003	0.0026
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0043	0.0022	0.0016
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0058	0.0071	0.5021
Schistosoma mansoni	hypothetical protein	0.0045	0.003	0.001
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0495	0.1521	0.1811
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0073	0.0121	1
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	beta 1 syntrophin	0.0045	0.003	0.0026
Echinococcus multilocularis	myotubularin protein 13	0.0045	0.003	0.0026
Leishmania major	protein kinase, putative	0.0055	0.0063	0.4146
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Trichomonas vaginalis	kinesin light chain, putative	0.0045	0.003	0.0199
Entamoeba histolytica	p21-activated kinase	0.0058	0.0071	0.0332
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0058	0.0071	0.0332
Brugia malayi	hypothetical protein	0.0284	0.082	0.0812
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0495	0.1521	0.1503
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.0058	0.0071	0.0469
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0043	0.0022	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.0058	0.0071	0.5021
Entamoeba histolytica	hypothetical protein	0.0495	0.1521	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0043	0.0022	0.0016
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Schistosoma mansoni	hypothetical protein	0.0284	0.082	0.0801
Trichomonas vaginalis	STE family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0043	0.0022	0.0016
Echinococcus multilocularis	expressed protein	0.0495	0.1521	0.1811
Brugia malayi	ephrin receptor 1 precursor	0.0043	0.0022	0.0013
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0495	0.1521	0.1513
Schistosoma mansoni	dynamin	0.0045	0.003	0.001
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Onchocerca volvulus		0.0045	0.003	0.0042
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0073	0.0121	0.0662
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Schistosoma mansoni	vav2	0.0045	0.003	0.001
Loa Loa (eye worm)	hypothetical protein	0.0495	0.1521	0.1513
Brugia malayi	Uncoordinated protein 104	0.0045	0.003	0.0022
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0495	0.1521	0.1503
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	TK/EPH protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trypanosoma cruzi	aurora B kinase, putative	0.0073	0.0121	1
Brugia malayi	hypothetical protein	0.0045	0.003	0.0022
Echinococcus granulosus	Oxysterol binding protein 11	0.0045	0.003	0.0026
Schistosoma mansoni	protein kinase	0.0055	0.0063	0.0042
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Echinococcus multilocularis	Pleckstrin y	0.0045	0.003	0.0026
Schistosoma mansoni	hypothetical protein	0.0124	0.0291	0.0272
Echinococcus multilocularis	regulator of G protein signaling	0.0495	0.1521	0.1811
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.0058	0.0071	0.5021
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0043	0.0022	0.0013
Echinococcus granulosus	dynamin 1	0.0045	0.003	0.0026
Schistosoma mansoni	regulator of G protein signaling	0.0495	0.1521	0.1503
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	oxysterol binding protein 9	0.0045	0.003	0.0026
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Entamoeba histolytica	protein kinase domain containing protein	0.0073	0.0121	0.0662
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0043	0.0022	0.0016
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0043	0.0022	0.0142
Echinococcus granulosus	Pleckstrin y	0.0045	0.003	0.0026
Echinococcus granulosus	regulator of G protein signaling 3	0.0495	0.1521	0.1811
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0083	0.0156	0.0147
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0055	0.0063	0.0065
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Onchocerca volvulus	Putative zinc finger protein	0.0045	0.003	0.0042
Entamoeba histolytica	cell surface protease gp63, putative	0.0124	0.0291	0.1801
Loa Loa (eye worm)	hypothetical protein	0.0284	0.082	0.0812
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.234	0.7637	0.7635
Entamoeba histolytica	hypothetical protein	0.0045	0.003	0.0058
Brugia malayi	Dynamin	0.0045	0.003	0.0022
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	protein kinase	0.0043	0.0022	0.0016
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0043	0.0022	0.0001
Brugia malayi	hypothetical protein	0.0495	0.1521	0.1513
Loa Loa (eye worm)	hypothetical protein	0.0665	0.2084	0.2077
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Brugia malayi	serine/threonine kinase 12	0.0073	0.0121	0.0112
Brugia malayi	Variant SH3 domain containing protein	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0083	0.0156	0.0147
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Echinococcus granulosus	tyrosine kinase	0.0043	0.0022	0.0016
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0045	0.003	0.0026
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0078	0.014	0.0131
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Brugia malayi	hypothetical protein	0.0043	0.0022	0.0013
Brugia malayi	SH2 domain containing protein	0.0043	0.0022	0.0013
Schistosoma mansoni	plexin	0.0381	0.1144	0.1126
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0495	0.1521	1
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0043	0.0022	0.0016
Entamoeba histolytica	hypothetical protein	0.0058	0.0071	0.0332
Schistosoma mansoni	hypothetical protein	0.0284	0.082	0.0801
Onchocerca volvulus		0.0045	0.003	0.0042
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0043	0.0022	0.0016
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0045	0.003	0.001
Loa Loa (eye worm)	hypothetical protein	0.0206	0.0564	0.0556
Schistosoma mansoni	hypothetical protein	0.0045	0.003	0.001
Schistosoma mansoni	oxysterol-binding protein 1	0.0045	0.003	0.001
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0043	0.0022	0.0013
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0045	0.003	0.0058
Trichomonas vaginalis	conserved hypothetical protein	0.0495	0.1521	1
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0045	0.003	0.0026
Entamoeba histolytica	hypothetical protein	0.0495	0.1521	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0043	0.0022	0.0016
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Loa Loa (eye worm)	hypothetical protein	0.0284	0.082	0.0812
Loa Loa (eye worm)	hypothetical protein	0.0284	0.082	0.0812
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.1845	0.5996	0.7171
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0043	0.0022	0.0001
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0045	0.003	0.0026
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0043	0.0022	0.0013
Schistosoma mansoni	regulator of G protein signaling	0.0495	0.1521	0.1503
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Entamoeba histolytica	hypothetical protein	0.0045	0.003	0.0058
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	regulator of G protein signaling 7	0.0495	0.1521	0.1811
Schistosoma mansoni	serine/threonine protein kinase	0.0043	0.0022	0.0001
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0045	0.003	0.0026
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0045	0.003	0.0026
Entamoeba histolytica	hypothetical protein	0.0124	0.0291	0.1801
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0043	0.0022	0.0013
Schistosoma mansoni	protein tyrosine kinase	0.0043	0.0022	0.0001
Brugia malayi	probable spectrin beta chain	0.0045	0.003	0.0022
Echinococcus granulosus	kinase suppressor of Ras 1	0.0043	0.0022	0.0016
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0045	0.003	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0078	0.014	0.0131
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Brugia malayi	plexin A	0.0789	0.2496	0.2489
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0043	0.0022	0.0001
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Echinococcus multilocularis	exocyst complex component 2	0.0124	0.0291	0.0339
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0495	0.1521	0.1503
Toxoplasma gondii	Oxysterol-binding protein	0.0045	0.003	0.0875
Echinococcus multilocularis	beta adrenergic receptor kinase	0.234	0.7637	0.9135
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0045	0.003	0.0026
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0045	0.003	0.0022
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0495	0.1521	0.1513
Schistosoma mansoni	protein kinase	0.0055	0.0063	0.0042
Brugia malayi	Cytohesin 3	0.0045	0.003	0.0022
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Loa Loa (eye worm)	TK/ALK protein kinase	0.0277	0.0799	0.0791
Brugia malayi	Sema domain containing protein	0.0284	0.082	0.0812
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0058	0.0071	0.5021
Entamoeba histolytica	protein kinase , putative	0.0073	0.0121	0.0662
Brugia malayi	hypothetical protein	0.0495	0.1521	0.1513
Schistosoma mansoni	semaphorin 5-related	0.0284	0.082	0.0801
Plasmodium vivax	hypothetical protein, conserved	0.0045	0.003	0.0875
Echinococcus granulosus	expressed protein	0.0495	0.1521	0.1811
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0045	0.003	0.001
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Echinococcus granulosus	ephrin type A receptor 4 A	0.0043	0.0022	0.0016
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	tyrosine protein kinase	0.0043	0.0022	0.0016
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0055	0.0063	0.4146
Echinococcus granulosus	roundabout 2	0.0083	0.0156	0.0176
Trichomonas vaginalis	AGC family protein kinase	0.0073	0.0121	0.0794
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK/INSR protein kinase	0.0043	0.0022	0.0013
Brugia malayi	Pleckstrin Homology Domain	0.0045	0.003	0.0022
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.2558	0.8359	1
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0045	0.003	0.0026
Entamoeba histolytica	protein kinase domain containing protein	0.0167	0.0433	0.2747
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Echinococcus granulosus	insulin receptor	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Echinococcus multilocularis	axis inhibition protein axin	0.0495	0.1521	0.1811
Loa Loa (eye worm)	sema domain-containing protein	0.0284	0.082	0.0812
Schistosoma mansoni	regulator of G protein signaling	0.0495	0.1521	0.1503
Onchocerca volvulus		0.0045	0.003	0.0042
Brugia malayi	Tyrosine-protein kinase abl-1	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	AGC family protein kinase	0.0073	0.0121	0.0794
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0045	0.003	0.0875
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0058	0.0071	0.5021
Loa Loa (eye worm)	hypothetical protein	0.0284	0.082	0.0812
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0045	0.003	0.0042
Echinococcus granulosus	pleckstrin y domain containing family A	0.0045	0.003	0.0026
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0045	0.003	0.0022
Echinococcus granulosus	axis inhibition protein axin	0.0495	0.1521	0.1811
Brugia malayi	Cadps2 protein	0.0045	0.003	0.0022
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Echinococcus granulosus	activated cdc42 kinase 1	0.0043	0.0022	0.0016
Echinococcus granulosus	neuroglian	0.0078	0.014	0.0157
Entamoeba histolytica	protein kinase domain containing protein	0.0055	0.0063	0.0274
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	centaurin alpha	0.0045	0.003	0.001
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Echinococcus multilocularis	protein kinase	0.0043	0.0022	0.0016
Leishmania major	hypothetical protein, conserved	0.0045	0.003	0.0875
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Echinococcus multilocularis	transfer RNA-Thr	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0078	0.014	0.0131
Schistosoma mansoni	tyrosine protein kinase	0.0043	0.0022	0.0001
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	Oxysterol binding protein	0.0045	0.003	0.0022
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Trichomonas vaginalis	CAMK family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0043	0.0022	0.0016
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	centaurin alpha, putative	0.0045	0.003	0.0199
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0045	0.003	0.0875
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	rho-GTPase-activating	0.0045	0.003	0.0022
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0055	0.0063	0.4146
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0045	0.003	0.0058
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.0058	0.0071	0.5021
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0043	0.0022	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0284	0.082	0.0812
Trichomonas vaginalis	alpha chimerin, putative	0.0045	0.003	0.0199
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Schistosoma mansoni	hypothetical protein	0.0045	0.003	0.001
Loa Loa (eye worm)	oxysterol binding protein	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	Plekhf2 protein	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trypanosoma cruzi	PH domain containing protein, putative	0.0045	0.003	0.0875
Schistosoma mansoni	goodpasture antigen-binding protein	0.0045	0.003	0.001
Toxoplasma gondii	hypothetical protein	0.0045	0.003	0.0875
Echinococcus multilocularis	oxysterol binding protein 1	0.0045	0.003	0.0026
Echinococcus multilocularis	pdz domain containing protein	0.0045	0.003	0.0026
Schistosoma mansoni	plexin	0.0665	0.2084	0.2068
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0043	0.0022	0.0016
Loa Loa (eye worm)	AUR protein kinase	0.0073	0.0121	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	aurora kinase A	0.0073	0.0121	0.0134
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Echinococcus multilocularis	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Echinococcus multilocularis	neuroglian	0.0078	0.014	0.0157
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Onchocerca volvulus		0.0045	0.003	0.0042
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0058	0.0071	0.0332
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	serine/threonine protein kinase	0.0043	0.0022	0.0013
Brugia malayi	C-terminal src kinase protein 1	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	PH domain-containing protein	0.0045	0.003	0.0022
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0043	0.0022	0.0016
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0043	0.0022	0.0016
Leishmania major	protein kinase, putative	0.0073	0.0121	1
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.0058	0.0071	0.0469
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Brugia malayi	A-kinase anchor protein 10, precursor	0.0495	0.1521	0.1513
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0045	0.003	0.0875
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Echinococcus granulosus	Pleckstrin y	0.0045	0.003	0.0026
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0043	0.0022	0.0013
Echinococcus multilocularis	epidermal growth factor receptor	0.0043	0.0022	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	Plekhf2 protein	0.0045	0.003	0.0022
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0045	0.003	0.0026
Entamoeba histolytica	PH domain containing protein	0.0045	0.003	0.0058
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0045	0.003	0.0058
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	integrin-linked kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	rho gtpase activating protein	0.0045	0.003	0.001
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0043	0.0022	0.0016
Echinococcus granulosus	defective proboscis extension response	0.0078	0.014	0.0157
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0043	0.0022	0.0016
Echinococcus multilocularis	dynamin 1	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0043	0.0022	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0124	0.0291	0.0283
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0043	0.0022	0.0016
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0058	0.0071	0.5021
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0043	0.0022	0.0142
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0495	0.1521	0.1811
Echinococcus multilocularis	tyrosine protein kinase	0.0043	0.0022	0.0016
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.0058	0.0071	0.5021
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0055	0.0063	0.4146
Trichomonas vaginalis	centaurin/arf, putative	0.0045	0.003	0.0199
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0058	0.0071	0.5021
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0045	0.003	0.0875
Echinococcus granulosus	receptor type guanylyl cyclase	0.0043	0.0022	0.0016
Echinococcus multilocularis	rac serine:threonine kinase	0.0058	0.0071	0.0075
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	myotubularin protein 13	0.0045	0.003	0.0026
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.0058	0.0071	0.5021
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0043	0.0022	0.0016
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0043	0.0022	0.0001
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0078	0.014	0.0157
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Echinococcus granulosus	DCC interacting protein 13 beta	0.0045	0.003	0.0026
Schistosoma mansoni	serine/threonine protein kinase	0.0073	0.0121	0.0101
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0078	0.014	0.012
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Schistosoma mansoni	myotubularin-related protein	0.0045	0.003	0.001
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0073	0.0121	1
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Loa Loa (eye worm)	uncoordinated protein 104	0.0045	0.003	0.0022
Schistosoma mansoni	serine/threonine protein kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	beta 1 syntrophin	0.0045	0.003	0.0026
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0073	0.0121	0.0134
Echinococcus granulosus	oxysterol binding protein 3	0.0045	0.003	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	centaurin/arf, putative	0.0045	0.003	0.0199
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0043	0.0022	0.0016
Schistosoma mansoni	zinc finger protein	0.0045	0.003	0.001
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0124	0.0291	0.1917
Trypanosoma brucei	protein kinase, putative	0.0058	0.0071	0.5021
Schistosoma mansoni	oxysterol-binding protein 1	0.0045	0.003	0.001
Echinococcus granulosus	protein kinase	0.0043	0.0022	0.0016
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0121	0.0282	0.0273
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	raf serine:threonine protein kinase	0.0043	0.0022	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0043	0.0022	0.0016
Echinococcus multilocularis	regulator of G protein signaling 7	0.0495	0.1521	0.1811
Schistosoma mansoni	fibrocystin l	0.0124	0.0291	0.0272
Toxoplasma gondii	hypothetical protein	0.0045	0.003	0.0875
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Echinococcus multilocularis	hypothetical protein	0.0284	0.082	0.0971
Echinococcus granulosus	G protein coupled receptor kinase 1	0.1845	0.5996	0.7171
Leishmania major	protein kinase, putative	0.0058	0.0071	0.5021
Echinococcus multilocularis	transcription factor collier	0.0124	0.0291	0.0339
Trypanosoma cruzi	NIMA-related kinase, putative	0.0058	0.0071	0.5021
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0058	0.0071	0.0332
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Trichomonas vaginalis	centaurin gamma, putative	0.0045	0.003	0.0199
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Onchocerca volvulus	outspread protein homolog	0.0045	0.003	0.0042
Schistosoma mansoni	regulator of G protein signaling	0.0495	0.1521	0.1503
Echinococcus granulosus	twitchin	0.0091	0.0181	0.0206
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0045	0.003	0.0026
Loa Loa (eye worm)	syntrophin-1	0.0045	0.003	0.0022
Echinococcus multilocularis	oxysterol binding protein 9	0.0045	0.003	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0043	0.0022	0.0016
Echinococcus multilocularis	protein tyrosine kinase	0.0043	0.0022	0.0016
Echinococcus granulosus	regulator of G protein signaling 7	0.0495	0.1521	0.1811
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Brugia malayi	SH2 domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Loa Loa (eye worm)	cytohesin 3	0.0045	0.003	0.0022
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Giardia lamblia	Aurora kinase	0.0073	0.0121	1
Schistosoma mansoni	serine/threonine protein kinase	0.0043	0.0022	0.0001
Echinococcus granulosus	c src tyrosine kinase	0.0043	0.0022	0.0016
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0045	0.003	0.0875
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0058	0.0071	0.0332
Echinococcus multilocularis	epidermal growth factor receptor	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0045	0.003	0.0875
Onchocerca volvulus		0.0045	0.003	0.0042
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.2558	0.8359	0.8358
Plasmodium falciparum	protein kinase, putative	0.0055	0.0063	0.4146
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Echinococcus granulosus	natriuretic peptide receptor 1	0.0043	0.0022	0.0016
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.2558	0.8359	0.8358
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0121	0.0282	0.0273
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0058	0.0071	0.5021
Entamoeba histolytica	hypothetical protein, conserved	0.0045	0.003	0.0058
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0058	0.0071	0.5021
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Brugia malayi	Fibronectin type III domain containing protein	0.0083	0.0156	0.0147
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0043	0.0022	0.0016
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0045	0.003	0.0026
Trypanosoma cruzi	PH domain containing protein, putative	0.0045	0.003	0.0875
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0043	0.0022	0.0016
Echinococcus granulosus	exocyst complex component 2	0.0124	0.0291	0.0339
Brugia malayi	Dynamin	0.0045	0.003	0.0022
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0043	0.0022	0.0013
Brugia malayi	Receptor family ligand binding region containing protein	0.0043	0.0022	0.0013
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0043	0.0022	0.0001
Onchocerca volvulus		0.0665	0.2084	1
Echinococcus granulosus	tyrosine kinase	0.0043	0.0022	0.0016
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Echinococcus multilocularis	roundabout 2	0.0083	0.0156	0.0176
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Leishmania major	hypothetical protein, conserved	0.0045	0.003	0.0875
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0045	0.003	0.0058
Echinococcus multilocularis	axis inhibition protein axin	0.0495	0.1521	0.1811
Loa Loa (eye worm)	TK/CSK protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	protein transport protein sec7, putative	0.0045	0.003	0.0199
Schistosoma mansoni	ephrin receptor	0.0048	0.0037	0.0017
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0495	0.1521	0.1513
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.0058	0.0071	0.5021
Leishmania major	serine/threonine-protein kinase a, putative	0.0058	0.0071	0.5021
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0043	0.0022	0.0016
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0124	0.0291	0.1917
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.0022	0.0016
Trypanosoma cruzi	PH domain containing protein, putative	0.0045	0.003	0.0875
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0043	0.0022	0.0013
Echinococcus granulosus	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0495	0.1521	1
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0284	0.082	0.0812
Echinococcus granulosus	axis inhibition protein axin	0.0495	0.1521	0.1811
Echinococcus multilocularis	activated cdc42 kinase 1	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0495	0.1521	1
Brugia malayi	Protein kinase domain containing protein	0.0277	0.0799	0.0792
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Brugia malayi	protein-tyrosine kinase	0.0043	0.0022	0.0013
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Brugia malayi	serine/threonine-protein kinase 6	0.0073	0.0121	0.0112
Brugia malayi	PXA domain containing protein	0.0495	0.1521	0.1513
Toxoplasma gondii	protein kinase domain-containing protein	0.0058	0.0071	0.5021
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Echinococcus multilocularis	c src tyrosine kinase	0.0043	0.0022	0.0016
Schistosoma mansoni	serine/threonine-protein kinase	0.0058	0.0071	0.0051
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0043	0.0022	0.0016
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Onchocerca volvulus		0.0284	0.082	0.3869
Echinococcus multilocularis	Immunoglobulin	0.0078	0.014	0.0157
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Toxoplasma gondii	AtPH1 family protein	0.0045	0.003	0.0875
Entamoeba histolytica	tyrosin kinase, putative	0.0167	0.0433	0.2747
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	TK protein kinase	0.0043	0.0022	0.0013
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Brugia malayi	Furin-like cysteine rich region family protein	0.0043	0.0022	0.0013
Trypanosoma cruzi	PH domain containing protein, putative	0.0045	0.003	0.0875
Echinococcus multilocularis	plexin a4	0.0789	0.2496	0.2979
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0495	0.1521	0.1811
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0045	0.003	0.0022
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0043	0.0022	0.0016
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Brugia malayi	hypothetical protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0124	0.0291	0.1917
Echinococcus granulosus	transcription factor collier	0.0124	0.0291	0.0339
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0058	0.0071	0.5021
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0045	0.003	0.0199
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Brugia malayi	hypothetical protein	0.0083	0.0156	0.0147
Trichomonas vaginalis	conserved hypothetical protein	0.0495	0.1521	1
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Echinococcus granulosus	tyrosine protein kinase Srms	0.0043	0.0022	0.0016
Echinococcus granulosus	tyrosine protein kinase csk	0.0043	0.0022	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0022	0.0142
Loa Loa (eye worm)	TK/ROR protein kinase	0.0043	0.0022	0.0013
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0048	0.0037	0.0035
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Loa Loa (eye worm)	TK/ACK protein kinase	0.0043	0.0022	0.0013
Entamoeba histolytica	hypothetical protein	0.0045	0.003	0.0058
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0043	0.0022	0.0016
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Schistosoma mansoni	serine/threonine protein kinase	0.234	0.7637	0.7632
Entamoeba histolytica	hypothetical protein	0.0124	0.0291	0.1801
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Loa Loa (eye worm)	SRC-1	0.0043	0.0022	0.0013
Echinococcus multilocularis	Immunoglobulin	0.0078	0.014	0.0157
Echinococcus multilocularis	actin binding protein anillin	0.0045	0.003	0.0026
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Echinococcus granulosus	tyrosine protein kinase HCK	0.0043	0.0022	0.0016
Echinococcus granulosus	activated cdc42 kinase 1	0.0043	0.0022	0.0016
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Echinococcus granulosus	beta-adrenergic receptor kinase	0.234	0.7637	0.9135
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0045	0.003	0.0058
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Entamoeba histolytica	protein kinase, putative	0.0073	0.0121	0.0662
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0043	0.0022	0.0013
Entamoeba histolytica	hypothetical protein	0.0045	0.003	0.0058
Trichomonas vaginalis	AGC family protein kinase	0.0073	0.0121	0.0794
Trypanosoma brucei	aurora B kinase	0.0073	0.0121	1
Entamoeba histolytica	PH domain containing protein	0.0045	0.003	0.0058
Echinococcus granulosus	tyrosine protein kinase pr2	0.0043	0.0022	0.0016
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Echinococcus granulosus	tyrosine protein kinase shark	0.0043	0.0022	0.0016
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0058	0.0071	0.0063
Brugia malayi	Syntrophin-1	0.0045	0.003	0.0022
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0495	0.1521	0.1513
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Brugia malayi	Tyrosine-protein kinase PR2	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0045	0.003	0.0026
Echinococcus multilocularis	tyrosine kinase	0.0043	0.0022	0.0016
Schistosoma mansoni	regulator of G protein signaling	0.0495	0.1521	0.1503
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0045	0.003	0.0199
Leishmania major	protein kinase, putative	0.0058	0.0071	0.5021
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0043	0.0022	0.0016
Echinococcus multilocularis	heat shock protein 70	0.0043	0.0022	0.0016
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0045	0.003	0.0042
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Brugia malayi	PH domain containing protein	0.0045	0.003	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0083	0.0156	0.0147
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0495	0.1521	1
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Schistosoma mansoni	protein kinase	0.0055	0.0063	0.0042
Schistosoma mansoni	serine/threonine protein kinase	0.234	0.7637	0.7632
Loa Loa (eye worm)	hypothetical protein	0.0045	0.003	0.0022
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Entamoeba histolytica	hypothetical protein	0.0495	0.1521	1
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Brugia malayi	SRC-1	0.0043	0.0022	0.0013
Onchocerca volvulus		0.0045	0.003	0.0042
Loa Loa (eye worm)	TK/ABL protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Schistosoma mansoni	protein kinase	0.0073	0.0121	0.0101
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.0058	0.0071	0.5021
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Schistosoma mansoni	axis inhibition protein axin	0.0495	0.1521	0.1503
Schistosoma mansoni	goodpasture antigen-binding protein	0.0045	0.003	0.001
Trypanosoma brucei	protein kinase, putative	0.0055	0.0063	0.4146
Loa Loa (eye worm)	hypothetical protein	0.0078	0.014	0.0131
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Schistosoma mansoni	tyrosine kinase	0.0043	0.0022	0.0001
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.0022	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0073	0.0121	0.0662
Schistosoma mansoni	hypothetical protein	0.0124	0.0291	0.0272
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.003	0.0199
Brugia malayi	Variant SH3 domain containing protein	0.0045	0.003	0.0022
Trichomonas vaginalis	AGC family protein kinase	0.0058	0.0071	0.0469
Echinococcus granulosus	Pleckstrin y	0.0045	0.003	0.0026
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0055	0.0063	0.0065
Trichomonas vaginalis	conserved hypothetical protein	0.0124	0.0291	0.1917
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0055	0.0063	0.4146
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus multilocularis	activin receptor type	0.0055	0.0063	0.0065
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.0058	0.0071	0.5021
Trypanosoma brucei	PH domain containing protein, putative	0.0045	0.003	0.0875
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0043	0.0022	0.0016
Schistosoma mansoni	protein kinase	0.0043	0.0022	0.0001
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0124	0.0291	0.1917
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0045	0.003	0.0022
Brugia malayi	Protein kinase domain containing protein	0.0043	0.0022	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0078	0.014	0.0131
Echinococcus granulosus	Rho GTPase activating protein 24	0.0045	0.003	0.0026
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0058	0.0071	0.5021
Echinococcus multilocularis	regulator of G protein signaling 3	0.0495	0.1521	0.1811
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0022	0.0013
Trichomonas vaginalis	TKL family protein kinase	0.0043	0.0022	0.0142
Echinococcus granulosus	epidermal growth factor receptor	0.0043	0.0022	0.0016
Trypanosoma cruzi	hypothetical protein	0.0045	0.003	0.0875
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0045	0.003	0.0199
Entamoeba histolytica	protein kinase, putative	0.0058	0.0071	0.0332
Echinococcus granulosus	integrin linked protein kinase	0.0043	0.0022	0.0016

Activities

Activity type	Activity value	Assay description	Source	Reference
MED (functional)	= 3 mg kg-1	Antiamnesic activity in ip dosed mouse assessed as reversal of scopolamine-induced amnesia after 20 mins by passive-avoidance test	ChEMBL.	21381762

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL1767001

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1510197