Detailed information for compound 1536408

Basic information

Technical information
  • TDR Targets ID: 1536408
  • Name: N-[(2S)-3-dimethylamino-2-hydroxypropyl]-4-me thyl-N-phenylbenzenesulfonamide
  • MW: 348.46 | Formula: C18H24N2O3S
  • H donors: 1 H acceptors: 3 LogP: 2.41 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C[C@@H](CN(S(=O)(=O)c1ccc(cc1)C)c1ccccc1)O)C
  • InChi: 1S/C18H24N2O3S/c1-15-9-11-18(12-10-15)24(22,23)20(14-17(21)13-19(2)3)16-7-5-4-6-8-16/h4-12,17,21H,13-14H2,1-3H3/t17-/m0/s1
  • InChiKey: DMHKLPBBWSMSJA-KRWDZBQOSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(2S)-3-dimethylamino-2-hydroxy-propyl]-4-methyl-N-phenyl-benzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus thyroid hormone receptor alpha 0.0096 0.1105 0.1949
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0036 0.0072
Brugia malayi nuclear hormone receptor 0.0096 0.1105 0.1569
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0179 0.0144
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0071 0.0788 0.1118
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0087 0.0153
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0337 0.0302
Brugia malayi hypothetical protein 0.0096 0.1105 0.1569
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0129 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0505
Onchocerca volvulus 0.0012 0.0037 0.009
Schistosoma mansoni lipoxygenase 0.0019 0.0136 0.0273
Schistosoma mansoni lipoxygenase 0.0054 0.0575 0.1159
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.124 0.2186
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0179 0.0144
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0096 0.1105 0.2229
Brugia malayi beta-lactamase family protein 0.0035 0.0337 0.0479
Brugia malayi Receptor family ligand binding region containing protein 0.0131 0.1543 0.219
Echinococcus multilocularis nuclear receptor nhr 48 0.0096 0.1105 0.1949
Echinococcus granulosus dna polymerase kappa 0.0019 0.013 0.0229
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0179 0.0144
Echinococcus granulosus GPCR family 2 0.0017 0.0111 0.0195
Schistosoma mansoni hypothetical protein 0.0275 0.3353 0.6765
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.013 0.0262
Echinococcus multilocularis expressed protein 0.0367 0.4514 0.7961
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0337 0.3736
Brugia malayi bZIP transcription factor family protein 0.0009 0.0008 0.0012
Echinococcus granulosus jun protein 0.0338 0.4151 0.7322
Echinococcus multilocularis tumor protein p63 0.0332 0.4076 0.7188
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0179 0.0144
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0096 0.1105 0.1949
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0001 0.0002
Mycobacterium leprae putative cytochrome p450 0.0023 0.0179 0.0132
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0129 0.0183
Echinococcus granulosus expressed protein 0.0367 0.4514 0.7961
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0259
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0259
Schistosoma mansoni hypothetical protein 0.0017 0.0111 0.0223
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0204 0.2465 0.3499
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Brugia malayi Immunoglobulin I-set domain containing protein 0.0071 0.0788 0.1119
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0072 0.0796 0.1604
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0111 0.0195
Echinococcus multilocularis carboxylesterase 5A 0.0068 0.0747 0.1317
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0141 0.0411
Leishmania major cytochrome p450-like protein 0.0023 0.0179 0.3929
Schistosoma mansoni hypothetical protein 0.0167 0.199 0.4014
Schistosoma mansoni zinc finger protein 0.0096 0.1105 0.2229
Onchocerca volvulus 0.0011 0.0036 0.0086
Brugia malayi Protein kinase domain containing protein 0.0071 0.0788 0.1119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Loa Loa (eye worm) RGC/RGC protein kinase 0.0011 0.0029 0.004
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0253 0.3082 0.4375
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Brugia malayi hypothetical protein 0.0108 0.1251 0.1776
Brugia malayi ecdysone receptor 0.0096 0.1105 0.1569
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0048 0.0067
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0179 0.0144
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0124 0.0089
Schistosoma mansoni hypothetical protein 0.0019 0.0136 0.0273
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0048 0.0505
Echinococcus granulosus single minded 2 0.0035 0.0337 0.0594
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Echinococcus granulosus netrin receptor unc 5 0.0071 0.0788 0.1389
Echinococcus granulosus BC026374 protein S09 family 0.0011 0.0036 0.0063
Echinococcus granulosus tyrosine kinase 0.0011 0.0029 0.005
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0179 0.3929
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0204 0.2465 0.4346
Schistosoma mansoni ap endonuclease 0.0018 0.0124 0.025
Brugia malayi hypoxia-induced factor 1 0.0148 0.1756 0.2493
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0129 0.0259
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0179 0.0144
Echinococcus multilocularis glutamate receptor 2 0.0011 0.0029 0.005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0179 0.3929
Echinococcus multilocularis FTZ F1 alpha 0.0204 0.2465 0.4346
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0011 0.0029 0.005
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0011 0.0029 0.005
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0087 0.0123
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0179 0.0144
Brugia malayi Carboxylesterase family protein 0.0068 0.0747 0.1061
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0575 0.1013
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0179 0.0144
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0096 0.1105 0.3398
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0048 0.0505
Schistosoma mansoni rab6-interacting 0.0019 0.0136 0.0273
Echinococcus granulosus RUN 0.0019 0.0136 0.0238
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0136 0.0192
Onchocerca volvulus 0.0204 0.2465 0.7609
Schistosoma mansoni cytochrome P450 0.0023 0.0179 0.0361
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0337 0.068
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0129 0.0259
Echinococcus granulosus cAMP responsive element binding protein 3 0.0009 0.0008 0.0014
Brugia malayi nuclear receptor NHR-67 0.0096 0.1105 0.1569
Loa Loa (eye worm) hypothetical protein 0.0035 0.0337 0.0478
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0048 0.0497
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0108 0.1251 0.1775
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0204 0.2465 0.4346
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0008 0.0014
Onchocerca volvulus 0.0035 0.0337 0.1019
Echinococcus granulosus atrial natriuretic peptide receptor 0.0011 0.0029 0.005
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0129 0.0226
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0129 0.0226
Mycobacterium tuberculosis Conserved protein 0.0035 0.0337 0.0302
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.013 0.0838
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0108 0.1251 0.2523
Onchocerca volvulus 0.0019 0.0136 0.0395
Mycobacterium ulcerans proteasome PrcA 0.0802 1 1
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0048 0.0505
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0204 0.2465 0.3499
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0337 0.8051
Loa Loa (eye worm) hypothetical protein 0.003 0.0266 0.0377
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0337 0.0302
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0071 0.0788 0.1389
Entamoeba histolytica hypothetical protein 0.0019 0.0129 0.0825
Echinococcus granulosus cyclic AMP dependent transcription factor ATF 6 0.0009 0.0008 0.0014
Echinococcus multilocularis C type lectin domian containing protein 0.0012 0.0037 0.0065
Giardia lamblia DINP protein human, muc B family 0.0019 0.013 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0136 0.1226
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0096 0.1105 0.1949
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.4957 0.8742
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0129 0.0183
Loa Loa (eye worm) hypothetical protein 0.0068 0.0747 0.106
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0048 0.0084
Loa Loa (eye worm) bZIP transcription factor family protein 0.0009 0.0008 0.0011
Echinococcus granulosus nuclear factor of activated T cells 5 0.0365 0.4484 0.7909
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0011 0.0036 0.0112
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0179 0.3871
Toxoplasma gondii exonuclease III APE 0.0018 0.0124 0.1474
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.013 0.265
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.013 0.0229
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Schistosoma mansoni retinoic acid receptor RXR 0.0204 0.2465 0.4972
Echinococcus granulosus Nuclear hormone receptor HR96 0.0096 0.1105 0.1949
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0124 0.1465
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0124 0.2418
Echinococcus multilocularis cyclic AMP dependent transcription factor ATF 6 0.0009 0.0008 0.0014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0204 0.2465 0.4972
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0204 0.2465 0.3499
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.1756 0.2492
Brugia malayi hypothetical protein 0.0019 0.0129 0.0183
Brugia malayi steroid hormone receptor 0.0204 0.2465 0.3499
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0153
Echinococcus granulosus nmda type glutamate receptor 0.0011 0.0029 0.005
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0048 0.0505
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.013 0.2579
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0129 0.0183
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0179 0.0144
Entamoeba histolytica hypothetical protein 0.0019 0.0129 0.0825
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.1436
Schistosoma mansoni hypothetical protein 0.0019 0.0129 0.0259
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Schistosoma mansoni cpg binding protein 0.003 0.0267 0.0538
Loa Loa (eye worm) hypothetical protein 0.0108 0.1251 0.1775
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0337 0.0302
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0108 0.1251 0.1776
Schistosoma mansoni camp-response element binding protein-related 0.0009 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0108 0.1251 0.1775
Echinococcus multilocularis RUN 0.0019 0.0136 0.0238
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0646 0.1302
Loa Loa (eye worm) hypothetical protein 0.0108 0.1251 0.1775
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0802 1 1
Chlamydia trachomatis endonuclease IV 0.0075 0.0841 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Brugia malayi hypothetical protein 0.016 0.1912 0.2715
Schistosoma mansoni polycystin 1-related 0.0019 0.0136 0.0273
Brugia malayi Steroid receptor seven-up type 2 0.0204 0.2465 0.3499
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0338 0.4151 0.7322
Schistosoma mansoni c4b-binding protein beta chain 0.0012 0.0037 0.0074
Brugia malayi pregnancy-associated plasma protein-A 0.0012 0.0037 0.0053
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0337 0.0291
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0108 0.1251 0.2523
Echinococcus granulosus C type lectin domian containing protein 0.0012 0.0037 0.0065
Brugia malayi CXXC zinc finger family protein 0.0028 0.0247 0.0351
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0136 0.1608
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0033 0.0095
Echinococcus multilocularis receptor type guanylyl cyclase 0.0011 0.0029 0.005
Onchocerca volvulus 0.0035 0.0337 0.1019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0337 0.0478
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0179 0.0144
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Brugia malayi Carboxylesterase family protein 0.0068 0.0747 0.1061
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0337 0.0302
Trypanosoma brucei unspecified product 0.0013 0.0056 0.0623
Echinococcus granulosus Ankyrin 0.0072 0.0796 0.1403
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0129 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.3158
Brugia malayi beta-lactamase 0.0035 0.0337 0.0479
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Schistosoma mansoni cpg binding protein 0.003 0.0267 0.0538
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.124 0.2501
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0008 0.0014
Mycobacterium ulcerans epimerase 0.002 0.0141 0.0105
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0087 0.103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0204 0.2465 0.4346
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0204 0.2465 0.4346
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0745 0.1057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0365 0.0518
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0179 0.0144
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0156 0.4039
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.013 0.0184
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.013 0.265
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0204 0.2465 0.3498
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0124 0.301
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0179 0.0144
Schistosoma mansoni tyrosine kinase 0.0011 0.0029 0.0057
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0129 0.0183
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0129 0.0226
Loa Loa (eye worm) glutamate receptor 0.003 0.0266 0.0377
Loa Loa (eye worm) hypothetical protein 0.0108 0.1251 0.1775
Brugia malayi follicle stimulating hormone receptor 0.0265 0.3228 0.4583
Schistosoma mansoni hypothetical protein 0.0017 0.0111 0.0223
Brugia malayi PXA domain containing protein 0.0019 0.0129 0.0183
Schistosoma mansoni rab6-interacting 0.0019 0.0136 0.0273
Toxoplasma gondii endonuclease IV APN 0.0075 0.0841 1
Brugia malayi metabotropic glutamate receptor type 2 0.003 0.0266 0.0378
Brugia malayi nuclear receptor NHR-88 0.0096 0.1105 0.1569
Schistosoma mansoni tyrosine kinase 0.0011 0.0029 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0204 0.2465 0.3499
Echinococcus multilocularis BC026374 protein (S09 family) 0.0011 0.0036 0.0063
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0337 0.068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0204 0.2465 0.3498
Brugia malayi Nuclear hormone receptor-like 1 0.0108 0.1251 0.1776
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0204 0.2465 0.3499
Mycobacterium ulcerans endonuclease IV 0.0075 0.0841 0.0807
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0247 0.035
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0012 0.0037 0.0052
Echinococcus granulosus acetylcholinesterase 0.0068 0.0747 0.1317
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0204 0.2465 0.4972
Echinococcus granulosus bloom syndrome protein 0.0021 0.0156 0.0274
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0124 0.0089
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0337 1
Brugia malayi bZIP transcription factor family protein 0.0009 0.0008 0.0012
Schistosoma mansoni RAR-like nuclear receptor 0.0204 0.2465 0.4972
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0087 0.103
Trypanosoma brucei unspecified product 0.0013 0.0056 0.0623
Mycobacterium tuberculosis Conserved protein 0.0035 0.0337 0.0302
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0129 0.0226
Schistosoma mansoni single-minded 0.0048 0.0494 0.0995
Onchocerca volvulus 0.0019 0.0136 0.0395
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0179 0.0144
Brugia malayi isocitrate dehydrogenase 0.0016 0.0087 0.0124
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.013 0.321
Onchocerca volvulus 0.0011 0.0029 0.0064
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0108 0.1251 0.2205
Brugia malayi tailless protein 0.0096 0.1105 0.1569
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.274 0.2714
Loa Loa (eye worm) RGC/RGC protein kinase 0.0011 0.0029 0.004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0337 0.0302
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0124 0.2491
Schistosoma mansoni hypothetical protein 0.0107 0.124 0.2501
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0337 0.0594
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0129 0.0226
Onchocerca volvulus 0.0012 0.0037 0.009
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0087 0.0175
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0179 0.0144
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0747 0.1507
Echinococcus granulosus tumor protein p63 0.0332 0.4076 0.7188
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0745 0.1313
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0111 0.0195
Loa Loa (eye worm) hypothetical protein 0.0035 0.0337 0.0478
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0337 0.0478
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0337 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0179 0.0144
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0337 0.0479
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0179 0.0144
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0129 0.0182
Echinococcus multilocularis tyrosine kinase 0.0011 0.0029 0.005
Echinococcus multilocularis metabotropic glutamate receptor 5 0.003 0.0266 0.0469
Loa Loa (eye worm) hypothetical protein 0.0108 0.1251 0.1775
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Schistosoma mansoni nuclear receptor 0.0096 0.1105 0.2229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0204 0.2465 0.4346
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0011 0.0036 0.0063
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.01 0.0201
Onchocerca volvulus 0.0012 0.0037 0.009
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0129 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0204 0.2465 0.3499
Echinococcus multilocularis cpg binding protein 0.003 0.0267 0.0471
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0179 0.0144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0153
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0129 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0204 0.2465 0.3499
Echinococcus granulosus tar DNA binding protein 0.0068 0.0745 0.1313
Plasmodium falciparum apical sushi protein 0.0012 0.0037 0.0435
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0204 0.2465 0.4346
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0337 0.0302
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0111 0.0157
Brugia malayi RNA binding protein 0.0068 0.0745 0.1058
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.013 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0129 0.0259
Loa Loa (eye worm) bZIP transcription factor family protein 0.0009 0.0008 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0141 0.0105
Brugia malayi beta-lactamase family protein 0.0035 0.0337 0.0479
Echinococcus multilocularis acetylcholinesterase 0.0068 0.0747 0.1317
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0565 0.6722
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.3158
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0011 0.0029 0.005
Brugia malayi Cytochrome P450 family protein 0.0041 0.0412 0.0585
Toxoplasma gondii ABC1 family protein 0.0035 0.0337 0.4009
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0111 0.0157
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0011 0.0029 0.0041
Schistosoma mansoni BC026374 protein (S09 family) 0.0011 0.0036 0.0072
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0048 0.0084
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0087 0.0124
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0124 0.0788
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0179 0.0144
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0136 0.0238
Schistosoma mansoni DNA polymerase eta 0.0019 0.013 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Echinococcus multilocularis jun protein 0.0338 0.4151 0.7322
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0 0.00000000059134
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0204 0.2465 0.3499
Loa Loa (eye worm) hypothetical protein 0.003 0.0266 0.0377
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0124 0.0218
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Onchocerca volvulus 0.0266 0.3237 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0585 0.083
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0087 0.0153
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0179 0.213
Brugia malayi nuclear hormone receptor 0.0204 0.2465 0.3499
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0011 0.0029 0.005
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0179 0.3929
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0129 0.0226
Echinococcus granulosus acetylcholinesterase 0.0068 0.0747 0.1317
Onchocerca volvulus 0.0012 0.0037 0.009
Loa Loa (eye worm) hypothetical protein 0.0072 0.0796 0.1129
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0124 0.1474
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.3228 0.4582
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.3158
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0745 0.1057
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0204 0.2465 0.3498
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Brugia malayi hypothetical protein 0.0019 0.0136 0.0192
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0179 0.0144
Onchocerca volvulus 0.0011 0.0036 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0204 0.2465 0.3499
Schistosoma mansoni glutamate receptor NMDA 0.0011 0.0029 0.0057
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0129 0.0259
Schistosoma mansoni gliotactin 0.0011 0.0036 0.0072
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0141 0.02
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0204 0.2465 0.3499
Brugia malayi nuclear receptor NHR-88 0.0204 0.2465 0.3499
Schistosoma mansoni protein kinase 0.0011 0.0029 0.0057
Brugia malayi Nuclear hormone receptor E75 0.0096 0.1105 0.1569
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.1105 0.1949
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0036 0.0072
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.124 0.2186
Loa Loa (eye worm) DR-78 0.0096 0.1105 0.1568
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.013 0.2579
Brugia malayi PAS domain containing protein 0.0048 0.0494 0.0701
Leishmania major cytochrome p450-like protein 0.0041 0.0412 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Brugia malayi nuclear receptor RXR 0.0108 0.1251 0.1776
Echinococcus granulosus glutamate receptor 2 0.0011 0.0029 0.005
Brugia malayi nuclear receptor RXR 0.0096 0.1105 0.1569
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0124 0.5
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.1518
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0337 0.0594
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0129 0.0183
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0412 1
Schistosoma mansoni nuclear receptor 0.0096 0.1105 0.2229
Brugia malayi bZIP transcription factor family protein 0.0338 0.4151 0.5893
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0337 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.013 0.0185
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0204 0.2465 0.4972
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0204 0.2465 0.4346
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0111 0.0195
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0019 0.0129 0.0374
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0056 0.0623
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0075 0.0841 0.0807
Brugia malayi PXA domain containing protein 0.0019 0.0129 0.0183
Brugia malayi Carboxylesterase family protein 0.0011 0.0036 0.0051
Brugia malayi Uncoordinated protein 44 0.0071 0.0788 0.1119
Onchocerca volvulus 0.0012 0.0037 0.009
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0129 0.0182
Brugia malayi Cytochrome P450 family protein 0.0023 0.0179 0.0255
Leishmania major cytochrome p450-like protein 0.0023 0.0179 0.3929
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0192
Brugia malayi Doublecortin family protein 0.0019 0.0136 0.0192
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0179 0.3929
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0048 0.0084
Loa Loa (eye worm) cytochrome P450 0.0023 0.0179 0.0254
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.1105 0.1949
Schistosoma mansoni camp-response element binding protein-related 0.0009 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0337 0.0478
Echinococcus multilocularis GPCR, family 2 0.0017 0.0111 0.0195
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0129 0.0226
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0129 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0204 0.2465 0.3498
Echinococcus granulosus Nuclear hormone receptor HR96 0.0096 0.1105 0.1949
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0048 0.0505
Echinococcus multilocularis neuropeptide s receptor 0.0459 0.567 1
Mycobacterium leprae conserved hypothetical protein 0.002 0.0141 0.0094
Brugia malayi Guanylyl cyclase protein 23 0.0011 0.0029 0.0041
Brugia malayi Nuclear hormone receptor E75 0.0096 0.1105 0.1569
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0124 0.9531
Schistosoma mansoni nuclear hormone receptor 0.0096 0.1105 0.2229
Trypanosoma brucei unspecified product 0.0019 0.013 0.2579
Loa Loa (eye worm) carboxylesterase 0.0011 0.0036 0.005
Echinococcus multilocularis c4b binding protein beta chain 0.0012 0.0037 0.0065
Echinococcus granulosus para nitrobenzyl esterase 0.0011 0.0036 0.0063
Loa Loa (eye worm) steroid hormone receptor 0.0204 0.2465 0.3498
Brugia malayi hypothetical protein 0.0011 0.0036 0.0051
Entamoeba histolytica hypothetical protein 0.0019 0.0129 0.0825
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0011
Brugia malayi Cytochrome P450 family protein 0.0084 0.0956 0.1357
Schistosoma mansoni acetylcholinesterase 0.0011 0.0036 0.0072
Toxoplasma gondii rhoptry neck protein RON1 0.0012 0.0037 0.0435
Brugia malayi nuclear hormone receptor family member odr-7 0.0096 0.1105 0.1569
Echinococcus multilocularis GPCR, family 3, C terminal 0.0019 0.0129 0.0226
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0068 0.0803
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0179 0.0144
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0019 0.0129 0.0259
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0259
Mycobacterium ulcerans hypothetical protein 0.002 0.0141 0.0105
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0745 0.1058
Leishmania major hypothetical protein, conserved 0.0035 0.0337 0.8051
Mycobacterium tuberculosis Conserved protein 0.0035 0.0337 0.0302
Schistosoma mansoni thyroid hormone receptor 0.0204 0.2465 0.4972
Onchocerca volvulus 0.0012 0.0037 0.009
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0179 0.0144
Onchocerca volvulus 0.0096 0.1105 0.3398
Schistosoma mansoni neuroligin 3 (S09 family) 0.0011 0.0036 0.0072
Loa Loa (eye worm) carboxylesterase 0.0011 0.0036 0.005
Loa Loa (eye worm) hypothetical protein 0.0075 0.0841 0.1193
Schistosoma mansoni hypothetical protein 0.0038 0.0365 0.0736
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0096 0.1105 0.1949
Echinococcus multilocularis cAMP responsive element binding protein 3 0.0009 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0011 0.0029 0.005
Loa Loa (eye worm) hypothetical protein 0.0568 0.7044 1
Brugia malayi Receptor family ligand binding region containing protein 0.0011 0.0029 0.0041
Mycobacterium ulcerans lipase LipD 0.0035 0.0337 0.0302
Brugia malayi conserved hypotetical protein 0.0096 0.1105 0.1569
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.3158
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.013 0.0095
Loa Loa (eye worm) hypothetical protein 0.0019 0.013 0.0184
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0124 0.1086
Echinococcus granulosus geminin 0.0167 0.199 0.3509
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0841 1
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0337 0.0479
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0204 0.2465 0.3499
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0337 0.0302
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0129 0.0226
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0096 0.1105 0.2229
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0337 0.8051
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0156 0.4039
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0129 0.0259
Loa Loa (eye worm) hypothetical protein 0.0017 0.0111 0.0157
Schistosoma mansoni thyroid hormone receptor 0.0204 0.2465 0.4972
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0124 0.2491
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.013 0.0262
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0036 0.0072
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0048 0.0497
Brugia malayi ecdysteroid receptor 0.0204 0.2465 0.3499
Schistosoma mansoni nuclear hormone receptor 0.0204 0.2465 0.4972
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0129 0.0226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0204 0.2465 0.3498
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.013 0.2579
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0575 0.1013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Echinococcus granulosus death domain containing protein 0.0071 0.0788 0.1389
Echinococcus multilocularis nmda type glutamate receptor 0.0011 0.0029 0.005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0182
Loa Loa (eye worm) nuclear hormone receptor 0.0096 0.1105 0.1568
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0204 0.2465 0.4972
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0124 0.2491
Onchocerca volvulus 0.0096 0.1105 0.3398
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.005
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0124 0.301
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0365 0.4484 0.7909
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0179 0.0144
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.013 0.0095
Echinococcus granulosus glutamate receptor 2 0.0011 0.0029 0.005
Echinococcus multilocularis expressed protein 0.0009 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0049 0.0504 0.0715
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0337 0.0594
Loa Loa (eye worm) hypothetical protein 0.0035 0.0337 0.0478
Echinococcus granulosus metabotropic glutamate receptor 5 0.003 0.0266 0.0469
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0129 0.0183
Echinococcus granulosus nuclear receptor nhr 48 0.0096 0.1105 0.1949
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0087 0.1518
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0412 0.0377
Onchocerca volvulus 0.0028 0.0247 0.074
Echinococcus multilocularis neuroligin 0.0011 0.0036 0.0063
Onchocerca volvulus 0.0012 0.0037 0.009
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0129 0.0182
Toxoplasma gondii rhoptry neck protein RON9 0.0012 0.0037 0.0435
Brugia malayi hypothetical protein 0.0266 0.3237 0.4595
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0412 0.0584
Echinococcus granulosus expressed protein 0.0009 0.0008 0.0014
Brugia malayi bZIP transcription factor family protein 0.0009 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0788 0.1118
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0111 0.0157
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0259
Loa Loa (eye worm) beta-lactamase 0.0035 0.0337 0.0478
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0067
Entamoeba histolytica hypothetical protein 0.0107 0.124 1
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0259
Schistosoma mansoni hypothetical protein 0.0009 0.0008 0.0016
Echinococcus granulosus dnaJ subfamily B 0.0402 0.4957 0.8742
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0841 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0337 0.0302
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0087 0.1436
Onchocerca volvulus 0.0012 0.0048 0.0123
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0001 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0745 0.1502
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0179 0.0144
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0136 0.0238
Leishmania major DNA polymerase eta, putative 0.0019 0.013 0.265
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0204 0.2465 0.4346
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0129 0.0259
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0129 0.3158
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0204 0.2465 0.4346
Echinococcus multilocularis Ankyrin 0.0072 0.0796 0.1403
Loa Loa (eye worm) nuclear receptor NHR-67 0.0096 0.1105 0.1568
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.013 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Schistosoma mansoni steroid hormone receptor ad4bp 0.0204 0.2465 0.4972
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0204 0.2465 0.4346
Brugia malayi Carboxylesterase family protein 0.0011 0.0036 0.0051
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0096 0.1105 0.1949
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0204 0.2465 0.4346
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Loa Loa (eye worm) hypothetical protein 0.002 0.0141 0.02
Loa Loa (eye worm) RNA binding protein 0.0068 0.0745 0.1057
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0129 0.0226
Echinococcus multilocularis fos transcription factor 0.0009 0.0008 0.0014
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0055 0.0585 0.083
Echinococcus granulosus metabotropic glutamate receptor 2 0.0011 0.0029 0.005
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0087 0.103
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0129 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.3158
Schistosoma mansoni hypothetical protein 0.0071 0.0788 0.1589
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0179 0.0144
Trichomonas vaginalis esterase, putative 0.0035 0.0337 1
Brugia malayi cytochrome P450 0.0023 0.0179 0.0255
Mycobacterium leprae Probable lipase LipE 0.0035 0.0337 0.0291
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0124 0.5
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0129 0.0226
Onchocerca volvulus Poor gastrulation protein homolog 0.0019 0.0129 0.0374
Brugia malayi hypothetical protein 0.0096 0.1105 0.1569
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0009 0.0008 0.0014
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0179 0.0144
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0585 0.083
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Loa Loa (eye worm) hypothetical protein 0.0068 0.0747 0.106
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0179 0.0144
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0179 0.0144
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0204 0.2465 0.4972
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0494 0.0995
Onchocerca volvulus Bile acid receptor homolog 0.0204 0.2465 0.7609
Schistosoma mansoni hypothetical protein 0.0017 0.0111 0.0223
Brugia malayi hypothetical protein 0.0009 0.0008 0.0012
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0096 0.1105 0.1568
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Loa Loa (eye worm) carboxylesterase 0.0068 0.0747 0.106
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0033 0.0095
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0412 1
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0019 0.0129 0.0183
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.007 0.0411
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Schistosoma mansoni cpg binding protein 0.0028 0.0247 0.0497
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0011 0.0029 0.004
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Onchocerca volvulus 0.0012 0.0037 0.009
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0136 0.0238
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0129 0.0226
Brugia malayi hypothetical protein 0.0019 0.0129 0.0183
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0048 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Brugia malayi orphan nuclear receptor NR2E1 0.0096 0.1105 0.1569
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0179 0.0316
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0745 0.1502
Echinococcus granulosus fos transcription factor 0.0009 0.0008 0.0014
Entamoeba histolytica hypothetical protein 0.0107 0.124 1
Brugia malayi Metabotropic glutamate receptor precursor. 0.003 0.0266 0.0378
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0337 1
Brugia malayi hypothetical protein 0.0019 0.0136 0.0192
Onchocerca volvulus 0.0011 0.0029 0.0064
Echinococcus multilocularis neuropeptide receptor A26 0.0459 0.567 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.013 0.0229
Schistosoma mansoni nuclear receptor nhr-48 0.0096 0.1105 0.2229
Onchocerca volvulus 0.0049 0.0504 0.1535
Echinococcus multilocularis ecdysone induced protein 78C 0.0204 0.2465 0.4346
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0505
Loa Loa (eye worm) RecQ helicase 0.0021 0.0156 0.022
Schistosoma mansoni nuclear hormone receptor 0.0096 0.1105 0.2229
Schistosoma mansoni hypothetical protein 0.0402 0.4957 1
Schistosoma mansoni hypothetical protein 0.0017 0.0111 0.0223
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.1518
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0745 0.1502
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0048 0.0505
Loa Loa (eye worm) hypothetical protein 0.0035 0.0337 0.0478
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Brugia malayi Cytochrome P450 family protein 0.0041 0.0412 0.0585
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Echinococcus granulosus neuroligin 0.0011 0.0036 0.0063
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0 0.0001
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0009 0.0008 0.0014
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0179 0.0132
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0365 0.0519
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Echinococcus multilocularis geminin 0.0167 0.199 0.3509
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0179 0.0144
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0048 0.0497
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0124 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0056 0.0623
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0412 0.0584
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0096 0.1105 0.1569
Loa Loa (eye worm) RGC/RGC protein kinase 0.0011 0.0029 0.004
Echinococcus granulosus c4b binding protein beta chain 0.0012 0.0037 0.0065
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0011 0.0029 0.005
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0129 0.0226
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0071 0.0788 0.1389
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0131 0.1543 0.2189
Loa Loa (eye worm) hypothetical protein 0.0018 0.0124 0.0175
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0156 0.0221
Echinococcus granulosus FTZ F1 alpha 0.0204 0.2465 0.4346
Brugia malayi hypothetical protein 0.0107 0.124 0.176
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0048 0.0497
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0048 0.0497
Brugia malayi nuclear hormone receptor family member nhr-6 0.0096 0.1105 0.1569
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0124 0.0218
Echinococcus granulosus cpg binding protein 0.003 0.0267 0.0471
Onchocerca volvulus 0.0012 0.0037 0.009
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0124 0.0176
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0204 0.2465 0.7609
Onchocerca volvulus 0.0035 0.0337 0.1019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0111 0.0195
Leishmania major DNA polymerase kappa, putative 0.0019 0.013 0.265
Echinococcus multilocularis thyroid hormone receptor alpha 0.0204 0.2465 0.4346
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0048 0.0505
Brugia malayi photoreceptor-specific nuclear receptor 0.0204 0.2465 0.3499
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0153
Schistosoma mansoni netrin receptor unc5 0.0071 0.0788 0.1589
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0136 0.0238
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0337 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0204 0.2465 0.4346
Loa Loa (eye worm) hypothetical protein 0.0204 0.2465 0.3498
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0204 0.2465 0.3499
Echinococcus multilocularis para nitrobenzyl esterase 0.0011 0.0036 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.013 0.265
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0504 0.1016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0204 0.2465 0.3498
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0192
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0136 0.0238
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0108 0.1251 0.2205
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0153
Entamoeba histolytica hypothetical protein 0.0107 0.124 1
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0009 0.0008 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.013 0.2579
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0179 0.0144
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0011 0.0029 0.005
Loa Loa (eye worm) hypothetical protein 0.0329 0.4035 0.5727
Schistosoma mansoni metabotropic glutamate receptor 0.003 0.0266 0.0536
Trichomonas vaginalis spcc417.12 protein, putative 0.0011 0.0036 0.0112
Brugia malayi GCC2 and GCC3 family protein 0.0012 0.0037 0.0053
Brugia malayi TAR-binding protein 0.0068 0.0745 0.1058
Echinococcus multilocularis glutamate receptor 2 0.0011 0.0029 0.005
Brugia malayi hypothetical protein 0.0012 0.0037 0.0053
Leishmania major protein kinase, putative 0.0012 0.0048 0.0497
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0179 0.0144
Onchocerca volvulus 0.0011 0.0036 0.0086
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0337 0.8033
Schistosoma mansoni jun-related protein 0.0275 0.3353 0.6765
Loa Loa (eye worm) bZIP transcription factor family protein 0.0009 0.0008 0.0011
Echinococcus granulosus receptor type guanylyl cyclase 0.0011 0.0029 0.005
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0156 0.0274
Loa Loa (eye worm) acetylcholinesterase 1 0.0068 0.0747 0.106
Schistosoma mansoni camp-response element binding protein-related 0.0009 0.0008 0.0016
Brugia malayi small heat shock protein 0.0568 0.7044 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0338 0.4151 0.7322
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0033 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0204 0.2465 0.3499
Echinococcus multilocularis dna polymerase kappa 0.0019 0.013 0.0229
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0011 0.0029 0.005
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0745 0.1502
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0179 0.0144
Schistosoma mansoni coup transcription factor 0.0204 0.2465 0.4972
Brugia malayi Death domain containing protein 0.0071 0.0788 0.1119
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0096 0.1105 0.1949
Onchocerca volvulus 0.0012 0.0037 0.009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0048 0.0505
Onchocerca volvulus 0.0011 0.0036 0.0086
Brugia malayi hypothetical protein 0.0108 0.1251 0.1776
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0412 0.0584
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0011 0.0036 0.0063
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0011 0.0029 0.0064
Schistosoma mansoni camp-response element binding protein 0.0009 0.0008 0.0016
Echinococcus multilocularis dna polymerase eta 0.0019 0.013 0.0229
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0337 0.0302
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0264 0.3219 0.4569
Schistosoma mansoni loxhd1 0.0019 0.0136 0.0273
Loa Loa (eye worm) hypothetical protein 0.016 0.1912 0.2714
Loa Loa (eye worm) cytochrome P450 family protein 0.0084 0.0956 0.1356
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0179 0.0144
Echinococcus granulosus GPCR family 3 C terminal 0.0019 0.0129 0.0226
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0204 0.2465 0.4346
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.013 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0505
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.013 0.321
Echinococcus multilocularis 0.0023 0.0179 0.0316
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0179 0.0144
Loa Loa (eye worm) glutamate receptor 0.0019 0.0129 0.0182
Loa Loa (eye worm) hypothetical protein 0.0017 0.0102 0.0144
Brugia malayi Carboxylesterase family protein 0.0011 0.0036 0.0051
Leishmania major protein kinase, putative 0.0012 0.0048 0.0497
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0179 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0056 0.0623
Echinococcus granulosus neuropeptide receptor A26 0.0459 0.567 1
Echinococcus granulosus ecdysone induced protein 78C 0.0204 0.2465 0.4346
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.013 0.265
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0745 0.1502
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0179 0.0144
Mycobacterium ulcerans beta-lactamase 0.0035 0.0337 0.0302
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0179 0.0144
Schistosoma mansoni ap endonuclease 0.0018 0.0124 0.025
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0129 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0204 0.2465 0.3499
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0179 0.0144
Echinococcus granulosus carboxylesterase 5A 0.0068 0.0747 0.1317
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0048 0.0497
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.013 0.265
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0204 0.2465 0.3498
Brugia malayi Carboxylesterase family protein 0.0011 0.0036 0.0051
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0011 0.0029 0.005
Schistosoma mansoni metabotropic glutamate receptor 0.0011 0.0029 0.0057
Schistosoma mansoni fos transcription factor-related 0.0009 0.0008 0.0016
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0179 0.0144
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0129 0.0226
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.013 0.265
Brugia malayi hypothetical protein 0.0011 0.0029 0.0041
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0136 0.0238
Onchocerca volvulus 0.0035 0.0337 0.1019
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0141 0.0105
Brugia malayi bZIP transcription factor family protein 0.0009 0.0008 0.0012
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0011 0.0029 0.005
Echinococcus multilocularis acetylcholinesterase 0.0068 0.0747 0.1317
Echinococcus granulosus dna polymerase eta 0.0019 0.013 0.0229
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.1568
Schistosoma mansoni hypothetical protein 0.0023 0.0179 0.0361
Schistosoma mansoni ankyrin 23/unc44 0.0071 0.0788 0.1589
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0048 0.0497
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0087 0.0622
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.3158
Onchocerca volvulus Netrin receptor homolog 0.0071 0.0788 0.2416
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0129 0.0182
Brugia malayi Sushi domain 0.0012 0.0037 0.0053
Mycobacterium ulcerans hypothetical protein 0.0035 0.0337 0.0302
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0075 0.0841 0.0796
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0204 0.2465 0.4972
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0412 1
Echinococcus multilocularis netrin receptor unc 5 0.0071 0.0788 0.1389
Onchocerca volvulus 0.0011 0.0036 0.0086
Loa Loa (eye worm) hypothetical protein 0.0012 0.0037 0.0052
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.013 0.2579
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0129 0.0259
Entamoeba histolytica hypothetical protein 0.0107 0.124 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0179 0.0144
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0075 0.0841 0.1193
Onchocerca volvulus Protein ultraspiracle homolog 0.0204 0.2465 0.7609
Schistosoma mansoni hypothetical protein 0.0167 0.199 0.4014
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0096 0.1105 0.3398
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0129 0.0226
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0179 0.0144
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0585 0.083
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0337 0.0302
Echinococcus granulosus neuropeptide s receptor 0.0459 0.567 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0087 0.0051

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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