Detailed information for compound 1616685

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 521.595 | Formula: C24H27N9O3S
  • H donors: 1 H acceptors: 6 LogP: 1.05 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#Cc1c(nc(c2n1cc(n2)CN1CCN(CC1)S(=O)(=O)C)N1CCOCC1)c1cccc2c1cn[nH]2
  • InChi: 1S/C24H27N9O3S/c1-37(34,35)32-7-5-30(6-8-32)15-17-16-33-21(13-25)22(18-3-2-4-20-19(18)14-26-29-20)28-23(24(33)27-17)31-9-11-36-12-10-31/h2-4,14,16H,5-12,15H2,1H3,(H,26,29)
  • InChiKey: JZTGIORHYWJCNQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta References
Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Starlite/ChEMBL References
Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha References
Homo sapiens phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Starlite/ChEMBL References
Homo sapiens mechanistic target of rapamycin (serine/threonine kinase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit Get druggable targets OG5_130060 All targets in OG5_130060
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum IPR000980,SH2 motif;IPR000198,RhoGAP;IPR008936,Rho GTPase activation protein,domain-containing Get druggable targets OG5_130060 All targets in OG5_130060
Giardia lamblia GTOR Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol 3-kinase, putative Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127444 All targets in OG5_127444
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_127444 All targets in OG5_127444
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130060 All targets in OG5_130060
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K07203 FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum expressed protein Get druggable targets OG5_130060 All targets in OG5_130060
Loa Loa (eye worm) phosphatidylinositol 3 Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum phosphatidylinositol 3-kinase 2, putative Get druggable targets OG5_127444 All targets in OG5_127444
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3-kinase, putative Get druggable targets OG5_127444 All targets in OG5_127444
Schistosoma japonicum ko:K02649 phosphoinositide-3-kinase, regulatory subunit, putative Get druggable targets OG5_130060 All targets in OG5_130060
Leishmania infantum target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative Get druggable targets OG5_127444 All targets in OG5_127444
Echinococcus multilocularis FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum IPR000198,RhoGAP;IPR008936,Rho GTPase activation protein,domain-containing Get druggable targets OG5_130060 All targets in OG5_130060
Brugia malayi SH2 domain containing protein Get druggable targets OG5_130060 All targets in OG5_130060
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127444 All targets in OG5_127444
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum IPR000980,SH2 motif;IPR001720,PI3 kinase, P85 regulatory subunit,domain-containing Get druggable targets OG5_130060 All targets in OG5_130060
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_130060 All targets in OG5_130060
Trypanosoma congolense Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) phosphatidylinositol 3 Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative Get druggable targets OG5_127444 All targets in OG5_127444
Leishmania braziliensis target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3-kinase (tor2)-like protein Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_130060 All targets in OG5_130060
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei phosphatidylinositol 4-kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol 3-kinase, putative Get druggable targets OG5_127444 All targets in OG5_127444
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative Get druggable targets OG5_127444 All targets in OG5_127444
Leishmania infantum target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit Get druggable targets OG5_130060 All targets in OG5_130060
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide Get druggable targets OG5_127444 All targets in OG5_127444
Candida albicans frameshifted from upsteam TOR2 CDS (CaP19.9461) Get druggable targets OG5_127212 All targets in OG5_127212
Neospora caninum Phosphatidylinositol 3-kinase tor2, related Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani phosphatidylinositol 3-kinase 2, putative Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative Get druggable targets OG5_127444 All targets in OG5_127444
Toxoplasma gondii target of rapamycin (TOR), putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K00922 phosphatidylinositol-4,5-bisphosphate 3-kinase [EC2.7.1.153], putative Get druggable targets OG5_127444 All targets in OG5_127444
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans frameshifted from upstream TOR2 CDS (CaP19.1905) Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis phosphatidylinositol kinase, putative Get druggable targets OG5_127444 All targets in OG5_127444
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130060 All targets in OG5_130060
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase Get druggable targets OG5_127444 All targets in OG5_127444
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Entamoeba histolytica phosphatidylinositol 3-kinase, putative phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1068 aa 927 aa 29.0 %
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 582 aa 491 aa 25.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi latrophilin 2 splice variant baaae 0.0079 0.1006 0.1104
Echinococcus granulosus protein tyrosine kinase 0.012 0.1598 0.1598
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0953
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0033 0.0355 0.0305
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.012 0.1598 0.3004
Brugia malayi Furin-like cysteine rich region family protein 0.012 0.1598 0.1754
Brugia malayi Cathepsin L-like precursor 0.0013 0.0063 0.0069
Plasmodium falciparum protein kinase, putative 0.012 0.1598 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Entamoeba histolytica cysteine surface protein, putative 0.012 0.1598 0.3004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) serine/threonine protein kinase 0.012 0.1598 0.1754
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0236 0.3281 0.3247
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Leishmania major phosphatidylinositol kinase, putative 0.0018 0.0135 0.047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Echinococcus multilocularis tyrosine protein kinase Blk 0.0356 0.5007 0.4981
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0236 0.3281 0.3601
Brugia malayi Cytochrome P450 family protein 0.0021 0.0173 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0952
Trypanosoma brucei protein kinase, putative 0.012 0.1598 0.9844
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Schistosoma mansoni serine/threonine RGC 0.012 0.1598 0.2237
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0094 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0867 0.163
Entamoeba histolytica hypothetical protein 0.0125 0.1678 0.3154
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0356 0.5007 0.9411
Entamoeba histolytica receptor protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0068 0.0856 0.1609
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0121 0.1622 0.178
Loa Loa (eye worm) fibroinase 0.0013 0.0063 0.0069
Entamoeba histolytica hypothetical protein 0.0028 0.0282 0.0529
Schistosoma mansoni adapter molecule crk 0.0236 0.3281 0.4594
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0104 0.1375 0.1508
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0856 0.5052
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0347 0.0381
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0015 0.0094 0.0132
Brugia malayi hypothetical protein 0.0028 0.0282 0.0309
Schistosoma mansoni tyrosine kinase 0.0356 0.5007 0.701
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Echinococcus multilocularis SHC transforming protein 3 0.0236 0.3281 0.3247
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.012 0.1598 0.3004
Brugia malayi Papain family cysteine protease containing protein 0.0013 0.0063 0.0069
Onchocerca volvulus 0.012 0.1598 0.3192
Echinococcus granulosus tyrosine protein kinase csk 0.012 0.1598 0.1598
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0015 0.0094 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0015 0.0094 0.0103
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0068 0.0856 0.1609
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.1598 0.1555
Onchocerca volvulus 0.0356 0.5007 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0028 0.0282 0.0232
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0015 0.0094 0.0103
Entamoeba histolytica serine/threonine kinase, putative 0.012 0.1598 0.3004
Echinococcus granulosus dual specificity testis-specific protein kinase 0.012 0.1598 0.1598
Plasmodium vivax tyrosine kinase-like protein, putative 0.012 0.1598 1
Echinococcus granulosus c src tyrosine kinase 0.0356 0.5007 0.5007
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0069 0.0867 0.153
Echinococcus multilocularis dual specificity testis specific protein kinase 0.012 0.1598 0.1555
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.012 0.1598 0.1555
Echinococcus granulosus tyrosine protein kinase Fyn 0.0356 0.5007 0.5007
Onchocerca volvulus 0.012 0.1598 0.3192
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0397 0.0348
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0397 0.0436
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.012 0.1598 1
Echinococcus granulosus FTZ F1 alpha 0.0015 0.0094 0.0094
Echinococcus granulosus tyrosine protein kinase Blk 0.0356 0.5007 0.5007
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0347 0.1765
Schistosoma mansoni smad 0.0012 0.0051 0.0071
Entamoeba histolytica serine/threonine kinase, putative 0.012 0.1598 0.3004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0015 0.0094 0.0103
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0347 0.054
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0063 0.0118
Schistosoma mansoni growth factor receptor-bound protein 0.0236 0.3281 0.4594
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.012 0.1598 0.1754
Schistosoma mansoni nck2/grb4 0.0236 0.3281 0.4594
Schistosoma mansoni tar DNA-binding protein 0.005 0.0593 0.083
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0015 0.0094 0.0094
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0135 0.0397
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.012 0.1598 0.1598
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0856 0.5166
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0015 0.0094 0.0043
Leishmania major phosphatidylinositol 3-kinase, putative 0.0068 0.0856 0.5166
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0074 0.0021
Trypanosoma brucei Flagellum attachment zone protein 20 0.012 0.1598 0.9844
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0068 0.0856 0.0809
Brugia malayi Cytochrome P450 family protein 0.0021 0.0173 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Loa Loa (eye worm) hypothetical protein 0.0036 0.0397 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0241 0.0453
Brugia malayi steroid hormone receptor 0.0015 0.0094 0.0103
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0397 0.0436
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0121 0.1622 0.2271
Echinococcus granulosus growth factor receptor bound protein 2 0.0236 0.3281 0.3281
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0068 0.0856 0.0856
Entamoeba histolytica hypothetical protein 0.0028 0.0282 0.0529
Schistosoma mansoni growth factor receptor-bound protein 0.0236 0.3281 0.4594
Brugia malayi Cathepsin L-like precursor 0.0013 0.0063 0.0069
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0482 0.6822 0.6822
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0347 0.0381
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.5007 0.4981
Onchocerca volvulus 0.012 0.1598 0.3192
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Echinococcus granulosus suppressor of cytokine signaling 7 0.0236 0.3281 0.3281
Echinococcus multilocularis thyroid hormone receptor alpha 0.0015 0.0094 0.0043
Leishmania major cytochrome p450-like protein 0.0021 0.0173 0.0719
Onchocerca volvulus 0.0356 0.5007 1
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Leishmania major cathepsin L-like protease 0.005 0.0598 0.3483
Brugia malayi Calcitonin receptor-like protein seb-1 0.0115 0.1531 0.168
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0514 0.072
Brugia malayi Probable tyrosine-protein kinase kin-31 0.012 0.1598 0.1754
Schistosoma mansoni hypothetical protein 0.012 0.1598 0.2237
Schistosoma mansoni hypothetical protein 0.0028 0.0282 0.0394
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0018 0.0135 0.0085
Trichomonas vaginalis STE family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus cathepsin L cysteine proteinase 0.0013 0.0063 0.0063
Schistosoma mansoni signal transduction protein lnk-related 0.0236 0.3281 0.4594
Brugia malayi beta-NAC-like protein 0.0026 0.0241 0.0264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0707 0.1329
Echinococcus multilocularis activin receptor type 0.012 0.1598 0.1555
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0243 0.3379 1
Onchocerca volvulus 0.0236 0.3281 0.6554
Echinococcus multilocularis FTZ F1 alpha 0.0015 0.0094 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein kinase Src64B 0.0356 0.5007 0.5007
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni hypothetical protein 0.0018 0.0135 0.0189
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0135 0.0148
Echinococcus granulosus integrin linked protein kinase 0.012 0.1598 0.1598
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.012 0.1598 0.1598
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0233 0.0233
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.012 0.1598 0.3004
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0015 0.0094 0.0094
Echinococcus granulosus SH2 motif 0.0236 0.3281 0.3281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0295 0.0554
Leishmania major protein kinase, putative 0.012 0.1598 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0236 0.3281 0.3281
Echinococcus granulosus transcription factor btf3 0.0026 0.0241 0.0241
Entamoeba histolytica protein kinase, putative 0.0125 0.1678 0.3154
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus multilocularis integrin linked protein kinase 0.012 0.1598 0.1555
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0015 0.0094 0.0103
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0033 0.0355 0.0355
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0094 0.0094
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0356 0.5007 0.4981
Echinococcus multilocularis tyrosine kinase 0.0356 0.5007 0.4981
Schistosoma mansoni steroid hormone receptor ad4bp 0.0015 0.0094 0.0132
Leishmania major cytochrome p450-like protein 0.0014 0.0074 0.007
Loa Loa (eye worm) TK/DDR protein kinase 0.012 0.1598 0.1754
Loa Loa (eye worm) hypothetical protein 0.0079 0.1006 0.1104
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0018 0.0135 0.047
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis receptor type guanylyl cyclase 0.012 0.1598 0.1555
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.012 0.1598 0.1754
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0094 0.0132
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0069 0.0867 0.0952
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0241 0.0264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0867 0.163
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Schistosoma mansoni transcription factor LCR-F1 0.0028 0.0282 0.0394
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0135 0.0137
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0015 0.0094 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0094 0.0043
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0347 0.0652
Echinococcus multilocularis protein kinase 0.012 0.1598 0.1555
Brugia malayi Protein kinase domain containing protein 0.0356 0.5007 0.5494
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0018 0.0135 0.0254
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0241 0.0453
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0952
Onchocerca volvulus 0.0236 0.3281 0.6554
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Toxoplasma gondii protein kinase domain-containing protein 0.012 0.1598 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Echinococcus multilocularis protein kinase 0.012 0.1598 0.1555
Onchocerca volvulus 0.0018 0.0135 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0347 0.0652
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0173 0.019
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.012 0.1598 0.3004
Onchocerca volvulus 0.0356 0.5007 1
Entamoeba histolytica SH2 domain containing protein 0.0236 0.3281 0.6167
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0236 0.3281 0.6167
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.012 0.1598 0.3004
Schistosoma mansoni tar DNA-binding protein 0.005 0.0593 0.083
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.012 0.1598 0.1555
Leishmania major protein kinase, putative 0.012 0.1598 1
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0018 0.0135 0.047
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi Tensin 0.0236 0.3281 0.3601
Echinococcus granulosus ecdysone induced protein 78C 0.0015 0.0094 0.0094
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0063 0.0088
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0397 0.0397
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Schistosoma mansoni coup transcription factor 0.0015 0.0094 0.0132
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0236 0.3281 0.4594
Echinococcus granulosus GPCR family 2 0.0036 0.0397 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Entamoeba histolytica protein kinase rad3, putative 0.0025 0.0233 0.0437
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0074 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0707 0.1329
Echinococcus multilocularis transfer RNA-Thr 0.012 0.1598 0.1555
Entamoeba histolytica hypothetical protein 0.0325 0.4554 0.856
Entamoeba histolytica serine/threonine kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) ctsf protein 0.0013 0.0063 0.0069
Schistosoma mansoni transcription factor btf3 0.0026 0.0241 0.0337
Echinococcus granulosus cathepsin l cysteine peptidase 0.0013 0.0063 0.0063
Echinococcus multilocularis ephrin type A receptor 4 A 0.012 0.1598 0.1555
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.012 0.1598 0.292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Echinococcus multilocularis cysteine protease 0.0013 0.0063 0.0012
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0069 0.0867 0.5238
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Echinococcus multilocularis SH2 motif 0.0236 0.3281 0.3247
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Entamoeba histolytica hypothetical protein 0.0018 0.0135 0.0254
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0236 0.3281 0.3601
Echinococcus multilocularis transcription factor btf3 0.0026 0.0241 0.0191
Schistosoma mansoni src-type protein tyrosine kinase-related 0.012 0.1598 0.2237
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Echinococcus granulosus kinase suppressor of Ras 1 0.012 0.1598 0.1598
Loa Loa (eye worm) cysteine protease 0.0013 0.0063 0.0069
Brugia malayi integrin-linked kinase 0.012 0.1598 0.1754
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0018 0.0135 0.047
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica serine/threonine kinase, putative 0.012 0.1598 0.3004
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.012 0.1598 0.3192
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0482 0.6822 0.6806
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0033 0.0355 0.0496
Echinococcus multilocularis SH2 motif 0.0236 0.3281 0.3247
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0135 0.0148
Echinococcus granulosus hypothetical protein 0.0236 0.3281 0.3281
Entamoeba histolytica serine/threonine kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Entamoeba histolytica hypothetical protein 0.0025 0.0233 0.0437
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0175 0.0192
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Schistosoma mansoni cytochrome P450 0.0014 0.0074 0.0103
Trichomonas vaginalis TK family protein kinase 0.012 0.1598 0.3004
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0236 0.3281 0.3247
Toxoplasma gondii target of rapamycin (TOR), putative 0.0055 0.0667 0.3932
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0094 0.0132
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0018 0.0135 0.0135
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0018 0.0135 0.0137
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Schistosoma mansoni hypothetical protein 0.0299 0.4182 0.5855
Echinococcus multilocularis activated cdc42 kinase 1 0.012 0.1598 0.1555
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0236 0.3281 0.3247
Loa Loa (eye worm) hypothetical protein 0.0097 0.1265 0.1388
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0236 0.3281 0.3247
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0397 0.0397
Echinococcus multilocularis retinal guanylyl cyclase 2 0.012 0.1598 0.1555
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Loa Loa (eye worm) cytochrome P450 0.0014 0.0074 0.0081
Echinococcus multilocularis tensin 0.0236 0.3281 0.3247
Brugia malayi Protein kinase domain containing protein 0.0356 0.5007 0.5494
Loa Loa (eye worm) transcription factor SMAD2 0.0181 0.2487 0.2729
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0325 0.4554 0.856
Echinococcus granulosus activated cdc42 kinase 1 0.012 0.1598 0.1598
Echinococcus granulosus tyrosine protein kinase Srms 0.0356 0.5007 0.5007
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0068 0.0856 0.0939
Giardia lamblia Kinase, NEK 0.012 0.1598 0.451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Entamoeba histolytica ankyrin repeat protein 0.012 0.1598 0.3004
Loa Loa (eye worm) phosphatidylinositol kinase 0.0018 0.0135 0.0148
Schistosoma mansoni RAR-like nuclear receptor 0.0015 0.0094 0.0132
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0236 0.3281 0.3601
Echinococcus granulosus SHC transforming protein 3 0.0236 0.3281 0.3281
Onchocerca volvulus 0.0013 0.0063 0.0126
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0069 0.0867 0.5124
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0233 0.1026
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Brugia malayi C-terminal src kinase protein 1 0.012 0.1598 0.1754
Brugia malayi SH2 domain containing protein 0.0236 0.3281 0.3601
Echinococcus granulosus N chimaerin 0.0236 0.3281 0.3281
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0707 0.1329
Brugia malayi Probable tyrosine-protein kinase kin-31 0.012 0.1598 0.1754
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis tyrosine protein kinase shark 0.0356 0.5007 0.4981
Loa Loa (eye worm) TK/KIN16 protein kinase 0.012 0.1598 0.1754
Echinococcus multilocularis signal transduction protein lnk realted 0.0236 0.3281 0.3247
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0241 0.108
Giardia lamblia Kinase, NEK 0.012 0.1598 0.451
Echinococcus granulosus Smad4 0.0012 0.0051 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Toxoplasma gondii histone lysine methyltransferase SET1 0.004 0.0446 0.2494
Echinococcus granulosus tyrosine kinase 0.012 0.1598 0.1598
Schistosoma mansoni hypothetical protein 0.0014 0.0074 0.0103
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0173 1
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Leishmania major hypothetical protein, unknown function 0.0018 0.0135 0.047
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0121 0.1622 0.2966
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.012 0.1598 0.1555
Loa Loa (eye worm) TK/CSK protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0121 0.1622 0.3049
Echinococcus granulosus smad 0.0012 0.0051 0.0051
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi RNA binding protein 0.005 0.0593 0.065
Echinococcus multilocularis cathepsin L cysteine protease 0.0013 0.0063 0.0012
Trypanosoma brucei Pseudokinase, putative 0.012 0.1598 0.9844
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0063 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Loa Loa (eye worm) hypothetical protein 0.0026 0.025 0.0274
Brugia malayi Raf kinase 0.012 0.1598 0.1754
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0233 0.1106
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0068 0.0856 0.0939
Echinococcus multilocularis retinal guanylyl cyclase 2 0.012 0.1598 0.1555
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0074 0.007
Entamoeba histolytica tyrosin kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0033 0.0355 0.0389
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.036 0.5058 0.9507
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0241 0.0453
Loa Loa (eye worm) TK/Met protein kinase 0.012 0.1598 0.1754
Echinococcus granulosus natriuretic peptide receptor 1 0.012 0.1598 0.1598
Loa Loa (eye worm) TK protein kinase 0.0356 0.5007 0.5494
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Entamoeba histolytica hypothetical protein 0.0026 0.0241 0.0453
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis dnaJ subfamily B 0.0299 0.4182 0.4152
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.1598 0.1555
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Plasmodium vivax protein kinase, putative 0.012 0.1598 1
Brugia malayi RNA recognition motif domain containing protein 0.005 0.0593 0.065
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Giardia lamblia GTOR 0.0069 0.0867 0.2256
Brugia malayi cytokine inducible SH2-containing protein 5 0.0236 0.3281 0.3601
Schistosoma mansoni tyrosine kinase 0.0356 0.5007 0.701
Onchocerca volvulus 0.0015 0.0094 0.0188
Onchocerca volvulus Huntingtin homolog 0.0097 0.1265 0.2527
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0015 0.0094 0.0132
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0135 0.0135
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0135 0.0148
Schistosoma mansoni tensin 0.0236 0.3281 0.4594
Toxoplasma gondii STE kinase 0.012 0.1598 1
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Schistosoma mansoni thyroid hormone receptor 0.0015 0.0094 0.0132
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Loa Loa (eye worm) hypothetical protein 0.0175 0.2396 0.2629
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Plasmodium falciparum protein kinase, putative 0.012 0.1598 1
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0953
Schistosoma mansoni serine/threonine protein kinase 0.012 0.1598 0.2237
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Schistosoma mansoni tyrosine-protein kinase fps85d 0.012 0.1598 0.2237
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.012 0.1598 0.1598
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Entamoeba histolytica hypothetical protein 0.0028 0.0282 0.0529
Schistosoma mansoni tensin 0.0236 0.3281 0.4594
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0068 0.0856 0.1198
Echinococcus multilocularis raf serine:threonine protein kinase 0.012 0.1598 0.1555
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus multilocularis c src tyrosine kinase 0.0356 0.5007 0.4981
Echinococcus granulosus insulin receptor 0.012 0.1598 0.1598
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0241 0.0339
Loa Loa (eye worm) RGC/RGC protein kinase 0.012 0.1598 0.1754
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0015 0.0094 0.0103
Brugia malayi hypothetical protein 0.012 0.1598 0.1754
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0068 0.0856 0.1609
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0347 0.1851
Echinococcus granulosus tyrosine protein kinase Btk29A 0.012 0.1598 0.1598
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Echinococcus multilocularis SH2 domain containing protein 7 0.0236 0.3281 0.3247
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0069 0.0867 0.0867
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0094 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.012 0.1598 0.2237
Schistosoma mansoni vav2 0.0236 0.3281 0.4594
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.004 0.0455 0.246
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0025 0.0233 0.0183
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0074 0.0021
Onchocerca volvulus 0.0018 0.0135 0.027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Brugia malayi MH1 domain containing protein 0.0012 0.0051 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0018 0.0135 0.0189
Brugia malayi Smad1 0.0012 0.0051 0.0056
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0236 0.3281 0.3601
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0856 0.5166
Onchocerca volvulus 0.0356 0.5007 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0015 0.0094 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0015 0.0094 0.0103
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0018 0.0135 0.047
Entamoeba histolytica hypothetical protein 0.0125 0.1678 0.3154
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0378 0.532 1
Entamoeba histolytica hypothetical protein 0.0028 0.0282 0.0529
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0069 0.0867 0.163
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0356 0.5007 0.4981
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0015 0.0094 0.0132
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus suppressor of cytokine signaling 6 0.0236 0.3281 0.3281
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0598 0.1017
Schistosoma mansoni tyrosine kinase 0.0356 0.5007 0.701
Echinococcus granulosus tyrosine protein kinase Fyn 0.0356 0.5007 0.5007
Loa Loa (eye worm) TK/KIN6 protein kinase 0.012 0.1598 0.1754
Echinococcus multilocularis tyrosine protein kinase 0.012 0.1598 0.1555
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0015 0.0094 0.0094
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0856 0.1509
Schistosoma mansoni suppressor of cytokine signaling 0.0236 0.3281 0.4594
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0598 0.1017
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.012 0.1598 0.9844
Brugia malayi hypothetical protein 0.0236 0.3281 0.3601
Echinococcus multilocularis NCK adaptor protein 0.0236 0.3281 0.3247
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi RhoGAP domain containing protein 0.0236 0.3281 0.3601
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0058 0.0708 0.42
Onchocerca volvulus 0.0356 0.5007 1
Brugia malayi protein-tyrosine kinase 0.0356 0.5007 0.5494
Onchocerca volvulus 0.012 0.1598 0.3192
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Echinococcus multilocularis epidermal growth factor receptor 0.012 0.1598 0.1555
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0015 0.0094 0.0043
Loa Loa (eye worm) Smad1 0.0012 0.0051 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0015 0.0094 0.0103
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0296 0.4145 0.7792
Echinococcus granulosus mothers against decapentaplegic 5 0.0012 0.0051 0.0051
Brugia malayi Cathepsin L-like precursor 0.0013 0.0063 0.0069
Loa Loa (eye worm) RNA binding protein 0.005 0.0593 0.065
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Brugia malayi Variant SH3 domain containing protein 0.0236 0.3281 0.3601
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Echinococcus granulosus tyrosine protein kinase Fyn 0.0356 0.5007 0.5007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Schistosoma mansoni tyrosine-protein kinase fps85d 0.012 0.1598 0.2237
Brugia malayi Receptor family ligand binding region containing protein 0.012 0.1598 0.1754
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0135 0.047
Brugia malayi STAT protein, DNA binding domain containing protein 0.0236 0.3281 0.3601
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) hypothetical protein 0.0641 0.9113 1
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Onchocerca volvulus 0.0013 0.0063 0.0126
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0548 0.1029
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.012 0.1598 0.1555
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) MH1 domain-containing protein 0.0012 0.0051 0.0056
Plasmodium falciparum tyrosine kinase-like protein 0.012 0.1598 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0233 0.0255
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Brugia malayi Variant SH3 domain containing protein 0.0236 0.3281 0.3601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0069 0.0867 0.1214
Onchocerca volvulus 0.0236 0.3281 0.6554
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0135 0.0254
Loa Loa (eye worm) STAT protein 0.0236 0.3281 0.3601
Schistosoma mansoni tyrosine kinase 0.0356 0.5007 0.701
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0236 0.3281 0.4594
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Onchocerca volvulus Cathepsin F homolog 0.0013 0.0063 0.0126
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0074 0.0074
Onchocerca volvulus 0.012 0.1598 0.3192
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0015 0.0094 0.0103
Echinococcus granulosus tyrosine protein kinase csk 0.012 0.1598 0.1598
Brugia malayi nuclear receptor NHR-88 0.0015 0.0094 0.0103
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0013 0.0063 0.0069
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0347 0.054
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Brugia malayi CXXC zinc finger family protein 0.0021 0.0175 0.0192
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0356 0.5007 0.5007
Loa Loa (eye worm) phosphatidylinositol 3 0.0103 0.136 0.1492
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Echinococcus granulosus expressed conserved protein 0.0236 0.3281 0.3281
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.012 0.1598 0.1598
Trypanosoma cruzi protein kinase, putative 0.012 0.1598 0.292
Schistosoma mansoni tyrosine protein kinase 0.012 0.1598 0.2237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0707 0.1329
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Loa Loa (eye worm) TK/RYK protein kinase 0.012 0.1598 0.1754
Loa Loa (eye worm) SH2 domain-containing protein 0.0236 0.3281 0.3601
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0203 0.2797 0.276
Toxoplasma gondii protein kinase 0.012 0.1598 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0397 0.0348
Loa Loa (eye worm) hypothetical protein 0.0018 0.0135 0.0148
Entamoeba histolytica tyrosin kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.012 0.1598 0.1555
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0236 0.3281 0.3601
Echinococcus granulosus tyrosine protein kinase Src42A 0.0236 0.3281 0.3281
Echinococcus multilocularis GPCR, family 2 0.0036 0.0397 0.0348
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0241 0.116
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi photoreceptor-specific nuclear receptor 0.0015 0.0094 0.0103
Brugia malayi Protein kinase domain containing protein 0.0356 0.5007 0.5494
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0013 0.0063 0.0118
Schistosoma mansoni fkbp-rapamycin associated protein 0.0025 0.0233 0.0326
Echinococcus multilocularis tar DNA binding protein 0.005 0.0593 0.0545
Echinococcus granulosus epidermal growth factor receptor 0.012 0.1598 0.1598
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0033 0.0355 0.0389
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0018 0.0135 0.0135
Giardia lamblia Kinase 0.012 0.1598 0.451
Loa Loa (eye worm) TK/EGFR protein kinase 0.012 0.1598 0.1754
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0241 0.0453
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0013 0.0063 0.0069
Loa Loa (eye worm) TK/ROR protein kinase 0.012 0.1598 0.1754
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.5007 0.4981
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0236 0.3281 0.6554
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0018 0.0135 0.0137
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0335 0.4701 0.4701
Schistosoma mansoni hypothetical protein 0.0099 0.1293 0.181
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0068 0.0856 0.0856
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0593 0.1114
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0707 0.1329
Leishmania major phosphatidylinositol 4-kinase, putative 0.0018 0.0135 0.047
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0069 0.0867 0.0821
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0046 0.0535 0.0897
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Echinococcus multilocularis 0.0236 0.3281 0.3247
Echinococcus granulosus protein kinase 0.012 0.1598 0.1598
Echinococcus multilocularis heat shock protein 70 0.012 0.1598 0.1555
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0094 0.0103
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0015 0.0094 0.0043
Brugia malayi MH2 domain containing protein 0.0181 0.2487 0.2729
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.012 0.1598 1
Schistosoma mansoni tyrosine kinase 0.0356 0.5007 0.701
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.012 0.1598 0.1754
Loa Loa (eye worm) hypothetical protein 0.0203 0.2797 0.3069
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0069 0.0867 0.153
Echinococcus multilocularis epidermal growth factor receptor 0.012 0.1598 0.1555
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Schistosoma mansoni suppressor of cytokine signaling 0.0236 0.3281 0.4594
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0236 0.3281 0.3247
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0347 0.1851
Brugia malayi SH2 domain containing protein 0.0236 0.3281 0.3601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0347 0.0486
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0012 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0233 0.0255
Loa Loa (eye worm) TK/INSR protein kinase 0.012 0.1598 0.1754
Echinococcus multilocularis microtubule associated protein 2 0.0504 0.7143 0.7128
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0241 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0233 0.0437
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0548 0.1029
Echinococcus granulosus microtubule associated protein 2 0.0504 0.7143 0.7143
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0378 0.532 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0867 0.163
Echinococcus granulosus fibroblast growth factor receptor 4 0.012 0.1598 0.1598
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0236 0.3281 0.6554
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Onchocerca volvulus 0.012 0.1598 0.3192
Schistosoma mansoni tensin 0.0236 0.3281 0.4594
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Trypanosoma cruzi cruzipain precursor, putative 0.005 0.0598 0.1017
Brugia malayi Sex muscle abnormal protein 5 0.0236 0.3281 0.3601
Echinococcus granulosus retinal guanylyl cyclase 2 0.012 0.1598 0.1598
Echinococcus multilocularis fibroblast growth factor receptor 4 0.012 0.1598 0.1555
Entamoeba histolytica serine/threonine kinase, putative 0.012 0.1598 0.3004
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0025 0.0233 0.0437
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Entamoeba histolytica hypothetical protein 0.0018 0.0135 0.0254
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.012 0.1598 0.1598
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0015 0.0094 0.0103
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.012 0.1598 0.1598
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0482 0.6822 0.9551
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.015 0.2031 0.3817
Brugia malayi MH2 domain containing protein 0.0012 0.0051 0.0056
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Mycobacterium leprae conserved hypothetical protein 0.0018 0.0135 1
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0125 0.1678 0.3154
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.012 0.1598 0.2237
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.012 0.1598 0.1555
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0236 0.3281 0.4594
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Entamoeba histolytica tyrosin kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.5007 0.4981
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0356 0.5007 0.4981
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Onchocerca volvulus 0.0236 0.3281 0.6554
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0356 0.5007 0.4981
Echinococcus granulosus tyrosine protein kinase Lyn 0.0356 0.5007 0.5007
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0068 0.0856 0.1198
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni retinoic acid receptor RXR 0.0015 0.0094 0.0132
Brugia malayi SH2 domain containing protein 0.0356 0.5007 0.5494
Schistosoma mansoni serine/threonine protein kinase 0.012 0.1598 0.2237
Loa Loa (eye worm) protein kinase domain-containing protein 0.012 0.1598 0.1754
Schistosoma mansoni smad1 5 8 and 0.0012 0.0051 0.0071
Onchocerca volvulus 0.0013 0.0063 0.0126
Echinococcus multilocularis natriuretic peptide receptor 1 0.012 0.1598 0.1555
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.012 0.1598 0.1754
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0856 0.1509
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0241 0.116
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Brugia malayi Tyrosine-protein kinase abl-1 0.0356 0.5007 0.5494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0953
Plasmodium vivax hypothetical protein 0.0018 0.0135 0.047
Schistosoma mansoni hypothetical protein 0.0036 0.0397 0.0556
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.012 0.1598 0.1555
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni ephrin receptor 0.012 0.1598 0.2237
Echinococcus granulosus tar DNA binding protein 0.005 0.0593 0.0593
Onchocerca volvulus Cathepsin L homolog 0.0013 0.0063 0.0126
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.012 0.1598 0.2237
Echinococcus multilocularis cpg binding protein 0.0022 0.0192 0.0142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0115 0.1531 0.168
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0236 0.3281 0.4594
Brugia malayi hypothetical protein 0.012 0.1598 0.1754
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0033 0.0355 0.0355
Echinococcus multilocularis kinase suppressor of Ras 1 0.012 0.1598 0.1555
Brugia malayi Cathepsin L-like precursor 0.0013 0.0063 0.0069
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0378 0.532 1
Echinococcus granulosus signal transduction protein lnk realted 0.0236 0.3281 0.3281
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.012 0.1598 0.1754
Onchocerca volvulus 0.012 0.1598 0.3192
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.012 0.1598 0.9844
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Schistosoma mansoni Smad4 0.0012 0.0051 0.0071
Echinococcus granulosus tyrosine protein kinase 0.012 0.1598 0.1598
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0025 0.0233 0.0323
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0018 0.0135 0.0189
Brugia malayi Variant SH3 domain containing protein 0.0236 0.3281 0.3601
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.012 0.1598 0.1555
Loa Loa (eye worm) TK/EPH protein kinase 0.012 0.1598 0.1754
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis cathepsin L cysteine protease 0.0013 0.0063 0.0012
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0058 0.0708 0.4094
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Brugia malayi SH2 domain containing protein 0.0236 0.3281 0.3601
Onchocerca volvulus Bile acid receptor homolog 0.0015 0.0094 0.0188
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0203 0.2797 0.3069
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0953
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.012 0.1598 0.1598
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0028 0.0282 0.0282
Echinococcus granulosus activin receptor type 0.012 0.1598 0.1598
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0135 0.047
Echinococcus granulosus activated cdc42 kinase 1 0.012 0.1598 0.1598
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0013 0.0063 0.0012
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0025 0.0233 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0552 0.1038
Schistosoma mansoni GTPase activating protein 0.0236 0.3281 0.4594
Schistosoma mansoni shc transforming protein 0.0236 0.3281 0.4594
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0121 0.1622 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Schistosoma mansoni smad1 5 8 and 0.0012 0.0051 0.0071
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0015 0.0094 0.0103
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0173 0.019
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0018 0.0135 0.047
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0356 0.5007 0.5007
Echinococcus granulosus dnaJ subfamily B 0.0299 0.4182 0.4182
Echinococcus granulosus epidermal growth factor receptor 0.012 0.1598 0.1598
Entamoeba histolytica ankyrin repeat protein 0.012 0.1598 0.3004
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0018 0.0135 0.0254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0347 0.0652
Brugia malayi ephrin receptor 1 precursor 0.012 0.1598 0.1754
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0135 0.047
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.012 0.1598 0.1754
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0015 0.0094 0.0103
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0236 0.3281 0.3281
Loa Loa (eye worm) TK/ACK protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.1598 0.1555
Brugia malayi Cytochrome P450 family protein 0.0044 0.0507 0.0557
Loa Loa (eye worm) TK/FER protein kinase 0.012 0.1598 0.1754
Onchocerca volvulus 0.0013 0.0063 0.0126
Echinococcus multilocularis 0.0014 0.0074 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0015 0.0094 0.0103
Echinococcus multilocularis tyrosine protein kinase pr2 0.012 0.1598 0.1555
Schistosoma mansoni hypothetical protein 0.0236 0.3281 0.4594
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) phosphatidylinositol 3 0.0429 0.6056 0.6646
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0236 0.3281 0.3247
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis protein tyrosine kinase 0.012 0.1598 0.1555
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0552 0.1038
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.1622 0.3049
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.012 0.1598 0.1598
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0356 0.5007 0.5007
Echinococcus multilocularis N chimaerin 0.0236 0.3281 0.3247
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0236 0.3281 0.3601
Onchocerca volvulus 0.0021 0.0175 0.035
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0356 0.5007 0.5007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Echinococcus granulosus tyrosine protein kinase Src42A 0.0356 0.5007 0.5007
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0233 0.0326
Entamoeba histolytica hypothetical protein 0.0125 0.1678 0.3154
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) phosphatidylinositol 3 0.0069 0.0867 0.0952
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Trichomonas vaginalis AGC family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0135 0.047
Echinococcus multilocularis SH2 motif 0.0236 0.3281 0.3247
Brugia malayi bone morphogenetic protein type 1 receptor 0.012 0.1598 0.1754
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0356 0.5007 0.701
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0015 0.0094 0.0094
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0135 0.0148
Loa Loa (eye worm) steroid hormone receptor 0.0015 0.0094 0.0103
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0018 0.0135 0.0137
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0015 0.0094 0.0103
Echinococcus granulosus tyrosine protein kinase ABL1 0.0356 0.5007 0.5007
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein kinase shark 0.0356 0.5007 0.5007
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0335 0.4701 0.4674
Trichomonas vaginalis protein tyrosine kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0018 0.0135 0.0189
Echinococcus multilocularis insulin receptor 0.012 0.1598 0.1555
Onchocerca volvulus 0.0236 0.3281 0.6554
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0507 0.0557
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0135 0.0148
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0173 0.021
Echinococcus multilocularis cysteine protease 0.0013 0.0063 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0033 0.0355 0.0496
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0378 0.532 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0233 0.0437
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0173 0.021
Echinococcus granulosus NCK adaptor protein 0.0236 0.3281 0.3281
Leishmania major cathepsin L-like protease 0.005 0.0598 0.3483
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0233 0.0255
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.5007 0.4981
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0033 0.0355 0.0305
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Brugia malayi MH1 domain containing protein 0.0012 0.0051 0.0056
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0856 0.5166
Brugia malayi hypothetical protein 0.0097 0.1265 0.1388
Brugia malayi Cathepsin L-like precursor 0.0013 0.0063 0.0069
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0069 0.0867 0.163
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0068 0.0856 0.5166
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0356 0.5007 0.4981
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0068 0.0856 0.5166
Onchocerca volvulus 0.0013 0.0063 0.0126
Schistosoma mansoni tar DNA-binding protein 0.005 0.0593 0.083
Leishmania major cytochrome p450-like protein 0.0014 0.0074 0.007
Echinococcus granulosus cpg binding protein 0.0022 0.0192 0.0192
Onchocerca volvulus Protein ultraspiracle homolog 0.0015 0.0094 0.0188
Brugia malayi Steroid receptor seven-up type 2 0.0015 0.0094 0.0103
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0135 0.0085
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.012 0.1598 0.3192
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0233 0.0323
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Echinococcus granulosus tyrosine protein kinase csk 0.012 0.1598 0.1598
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Entamoeba histolytica hypothetical protein, conserved 0.012 0.1598 0.3004
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Plasmodium falciparum tyrosine kinase-like protein 0.012 0.1598 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0094 0.0043
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0026 0.025 0.1216
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Echinococcus granulosus retinal guanylyl cyclase 2 0.012 0.1598 0.1598
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0018 0.0135 0.0397
Schistosoma mansoni tar DNA-binding protein 0.005 0.0593 0.083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0033 0.0355 0.0496
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.012 0.1598 0.1754
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0015 0.0094 0.0132
Echinococcus multilocularis Zinc finger, PHD finger 0.0068 0.0856 0.0809
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Schistosoma mansoni microtubule-associated protein tau 0.0504 0.7143 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.012 0.1598 1
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0094 0.0103
Trichomonas vaginalis serine-threonine protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Onchocerca volvulus 0.012 0.1598 0.3192
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0069 0.0867 0.5238
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0347 0.1765
Loa Loa (eye worm) SRC-1 0.0356 0.5007 0.5494
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0356 0.5007 0.4981
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0135 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0609 0.1146
Schistosoma mansoni tensin-related 0.0236 0.3281 0.4594
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0236 0.3281 0.3281
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0015 0.0094 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Leishmania major basic transcription factor 3a, putative 0.0026 0.0241 0.116
Trichomonas vaginalis protein kinase atn1, putative 0.012 0.1598 0.3004
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Leishmania major hypothetical protein, conserved 0.0018 0.0135 0.047
Echinococcus granulosus SH2 domain containing protein 7 0.0236 0.3281 0.3281
Brugia malayi Protein kinase domain containing protein 0.0356 0.5007 0.5494
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Echinococcus multilocularis tyrosine protein kinase Abl 0.0356 0.5007 0.4981
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis CAMK family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0015 0.0094 0.0132
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Brugia malayi nuclear hormone receptor 0.0015 0.0094 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0233 0.0437
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.1598 0.1555
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0236 0.3281 0.3247
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) TK/ABL protein kinase 0.0356 0.5007 0.5494
Echinococcus granulosus tyrosine kinase 0.0356 0.5007 0.5007
Schistosoma mansoni protein tyrosine kinase 0.012 0.1598 0.2237
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0347 0.0298
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Schistosoma mansoni serine/threonine protein kinase 0.012 0.1598 0.2237
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.012 0.1598 0.292
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0068 0.0856 0.1609
Brugia malayi Cytochrome P450 family protein 0.0014 0.0074 0.0081
Plasmodium vivax tyrosine kinase-like protein, putative 0.012 0.1598 1
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Echinococcus multilocularis ecdysone induced protein 78C 0.0015 0.0094 0.0043
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0552 0.1038
Loa Loa (eye worm) hypothetical protein 0.0356 0.5007 0.5494
Schistosoma mansoni ephrin receptor 0.012 0.1598 0.2237
Brugia malayi SH2 domain containing protein 0.0356 0.5007 0.5494
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0018 0.0135 0.047
Leishmania major hypothetical protein, conserved 0.012 0.1598 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0135 0.0254
Echinococcus granulosus receptor type guanylyl cyclase 0.012 0.1598 0.1598
Echinococcus multilocularis expressed conserved protein 0.0099 0.1293 0.1248
Loa Loa (eye worm) MH2 domain-containing protein 0.0181 0.2487 0.2729
Loa Loa (eye worm) RGC/RGC protein kinase 0.012 0.1598 0.1754
Entamoeba histolytica receptor protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0121 0.1622 0.3049
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0356 0.5007 0.4981
Loa Loa (eye worm) TK protein kinase 0.012 0.1598 0.1754
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0037 0.041 0.2169
Schistosoma mansoni cpg binding protein 0.0022 0.0192 0.0269
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Loa Loa (eye worm) TK/ALK protein kinase 0.012 0.1598 0.1754
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0015 0.0094 0.0103
Schistosoma mansoni tensin-related 0.0236 0.3281 0.4594
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) RGC/RGC protein kinase 0.012 0.1598 0.1754
Brugia malayi hypothetical protein 0.0356 0.5007 0.5494
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0397 0.0436
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0103 0.136 0.2467
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Echinococcus granulosus SH2 domain containing adapter protein F 0.0236 0.3281 0.3281
Brugia malayi ecdysteroid receptor 0.0015 0.0094 0.0103
Echinococcus granulosus TGF beta signal transducer SmadC 0.0012 0.0051 0.0051
Loa Loa (eye worm) RGC/RGC protein kinase 0.012 0.1598 0.1754
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0296 0.4145 0.7792
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Loa Loa (eye worm) hypothetical protein 0.0097 0.1265 0.1388
Echinococcus multilocularis retinal guanylyl cyclase 2 0.012 0.1598 0.1555
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0347 0.0652
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0121 0.1622 0.3049
Brugia malayi Tyrosine-protein kinase PR2 0.012 0.1598 0.1754
Entamoeba histolytica tyrosin kinase, putative 0.012 0.1598 0.3004
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0035
Loa Loa (eye worm) TAR-binding protein 0.005 0.0593 0.065
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Onchocerca volvulus Cathepsin L homolog 0.0013 0.0063 0.0126
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0356 0.5007 0.4981
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.1622 0.3049
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.005 0.0593 0.065
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0598 0.1017
Onchocerca volvulus 0.0356 0.5007 1
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.012 0.1598 0.1598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0667 0.1253
Brugia malayi MH2 domain containing protein 0.0012 0.0051 0.0056
Schistosoma mansoni cpg binding protein 0.0022 0.0192 0.0269
Schistosoma mansoni smad1 5 8 and 0.0012 0.0051 0.0071
Giardia lamblia Protein 21.1 0.012 0.1598 0.451
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0135 0.0148
Echinococcus multilocularis 0.0018 0.0135 0.0085
Brugia malayi Variant SH3 domain containing protein 0.0236 0.3281 0.3601
Schistosoma mansoni tyrosine kinase 0.0356 0.5007 0.701
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0236 0.3281 0.3247
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0015 0.0094 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0753 0.1415
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.5007 0.5494
Schistosoma mansoni protein kinase 0.012 0.1598 0.2237
Brugia malayi SH2 domain containing protein 0.0236 0.3281 0.3601
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0356 0.5007 0.4981
Echinococcus multilocularis growth factor receptor bound protein 2 0.0236 0.3281 0.3247
Echinococcus multilocularis tyrosine kinase 0.012 0.1598 0.1555
Brugia malayi TAR-binding protein 0.005 0.0593 0.065
Schistosoma mansoni hypothetical protein 0.0036 0.0397 0.0556
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0069 0.0867 0.5124
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0135 0.0137
Entamoeba histolytica hypothetical protein 0.012 0.1598 0.3004
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0356 0.5007 0.5007
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi SH2 domain containing protein 0.0236 0.3281 0.3601
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0135 0.0148
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0347 0.0347
Schistosoma mansoni hypothetical protein 0.0079 0.1006 0.1409
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus retinal guanylyl cyclase 2 0.012 0.1598 0.1598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0135 0.0254
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0063 0.0118
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0236 0.3281 0.3601
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Brugia malayi SH2 domain containing protein 0.0236 0.3281 0.3601
Echinococcus granulosus cathepsin l1 0.0013 0.0063 0.0063
Brugia malayi Guanylyl cyclase protein 23 0.012 0.1598 0.1754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0507 0.0952
Entamoeba histolytica tyrosine kinase, putative 0.012 0.1598 0.3004
Schistosoma mansoni SH2A 0.0236 0.3281 0.4594
Brugia malayi SH2 domain containing protein 0.0641 0.9113 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0135 1
Echinococcus multilocularis FL cytokine receptor 0.012 0.1598 0.1555
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0236 0.3281 0.4594
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.012 0.1598 0.2237
Echinococcus multilocularis protein KINase family member (kin 25) 0.012 0.1598 0.1555
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0013 0.0063 0.0012
Echinococcus multilocularis tyrosine protein kinase Srms 0.0356 0.5007 0.4981
Onchocerca volvulus 0.0013 0.0063 0.0126
Echinococcus granulosus tyrosine protein kinase pr2 0.012 0.1598 0.1598
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Trichomonas vaginalis conserved hypothetical protein 0.012 0.1598 0.3004
Entamoeba histolytica hypothetical protein 0.0018 0.0135 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0013 0.0063 0.0118
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.012 0.1598 0.1754
Schistosoma mansoni tar DNA-binding protein 0.005 0.0593 0.083
Loa Loa (eye worm) hypothetical protein 0.0115 0.1531 0.168
Entamoeba histolytica protein kinase domain containing protein 0.012 0.1598 0.3004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Echinococcus granulosus expressed conserved protein 0.0099 0.1293 0.1293
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0015 0.0094 0.0103
Onchocerca volvulus 0.012 0.1598 0.3192
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0173 0.0643
Loa Loa (eye worm) MH2 domain-containing protein 0.0012 0.0051 0.0056
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0203 0.2797 0.2797
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trypanosoma cruzi major cysteine proteinase, putative 0.004 0.0442 0.0722
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) SH2 domain-containing protein 0.0236 0.3281 0.3601
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0378 0.532 1
Echinococcus multilocularis tensin 0.0236 0.3281 0.3247
Loa Loa (eye worm) hypothetical protein 0.012 0.1598 0.1754
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0094 0.0094
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0074 0.007
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Loa Loa (eye worm) SH2 domain-containing protein 0.0236 0.3281 0.3601
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0115 0.1531 0.168
Echinococcus granulosus insulin growth factor 1 receptor beta 0.012 0.1598 0.1598
Schistosoma mansoni hypothetical protein 0.0036 0.0397 0.0556
Echinococcus multilocularis tyrosine protein kinase HCK 0.012 0.1598 0.1555
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Schistosoma mansoni cpg binding protein 0.0021 0.0175 0.0245
Brugia malayi Protein kinase domain containing protein 0.012 0.1598 0.1754
Loa Loa (eye worm) hypothetical protein 0.0013 0.0063 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0094 0.0132
Onchocerca volvulus 0.0236 0.3281 0.6554
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0071 0.0901 0.2362
Onchocerca volvulus Huntingtin homolog 0.0097 0.1265 0.2527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0063 0.0118
Brugia malayi tRNA modification GTPase TrmE family protein 0.0236 0.3281 0.3601
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.012 0.1598 0.1555
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Trypanosoma cruzi target of rapamycin kinase 3 0.0058 0.0708 0.1226
Onchocerca volvulus 0.0013 0.0063 0.0126
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.012 0.1598 0.1598
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0063 0.0118
Schistosoma mansoni hypothetical protein 0.0036 0.0397 0.0556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.005 0.0598 0.3384
Plasmodium falciparum protein kinase, putative 0.012 0.1598 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0347 0.0652
Loa Loa (eye worm) hypothetical protein 0.0236 0.3281 0.3601
Brugia malayi Cathepsin L-like precursor 0.0013 0.0063 0.0069
Schistosoma mansoni tyrosine kinase 0.012 0.1598 0.2237
Brugia malayi cytochrome P450 0.0014 0.0074 0.0081
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0135 0.0085
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0236 0.3281 0.3281
Onchocerca volvulus Tyrosine kinase homolog 0.012 0.1598 0.3192
Trypanosoma cruzi protein kinase, putative 0.012 0.1598 0.292
Schistosoma mansoni hypothetical protein 0.0236 0.3281 0.4594
Echinococcus granulosus ephrin type A receptor 4 A 0.012 0.1598 0.1598
Echinococcus granulosus SH2 motif 0.0236 0.3281 0.3281
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0103
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0233 0.0183
Echinococcus granulosus tyrosine kinase 0.0356 0.5007 0.5007
Entamoeba histolytica protein kinase, putative 0.012 0.1598 0.3004
Echinococcus granulosus tyrosine protein kinase HCK 0.012 0.1598 0.1598
Loa Loa (eye worm) TK/FAK protein kinase 0.012 0.1598 0.1754
Brugia malayi SRC-1 0.0356 0.5007 0.5494
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0378 0.532 0.5838
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0241 0.116
Entamoeba histolytica cysteine protease, putative 0.0013 0.0063 0.0118
Leishmania major cathepsin L-like protease 0.005 0.0598 0.3483
Brugia malayi Protein kinase domain containing protein 0.0356 0.5007 0.5494
Echinococcus granulosus raf serine:threonine protein kinase 0.012 0.1598 0.1598
Entamoeba histolytica protein kinase, putative 0.0236 0.3281 0.6167
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0378 0.532 1
Trichomonas vaginalis TKL family protein kinase 0.012 0.1598 0.3004
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0173 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.025 0.0469
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0068 0.0856 0.1609
Echinococcus granulosus tensin 0.0236 0.3281 0.3281

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 0.203 uM Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cells ChEMBL. 22325943
IC50 (binding) = 0.194 uM Inhibition of PI3K p110alpha/p85alpha ChEMBL. 22325943
IC50 (binding) > 10 uM Inhibition of mTOR ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of AKT1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of ARK5 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of CK1alpha1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of DYRK1A at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of EGF-R at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of FAK at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of FGF-R1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of FLT3 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of IGF1-R at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of IKK-beta at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of INS-R at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of JAK2 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of JNK1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of KIT at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of MEK1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of MET at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of MST1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of PAK1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of PIM1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of PIM2 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of RPS6KA1 at 5 to 10 uM ChEMBL. 22325943
Inhibition (binding) = 50 % Inhibition of SGK1 at 5 to 10 uM ChEMBL. 22325943
Ki (binding) = 43 nM Inhibition of human PI3K p110delta/p85alpha ChEMBL. 22325943
Ki (binding) = 410 nM Inhibition of human PI3K p110alpha/p85alpha ChEMBL. 22325943
Ki (binding) > 500 nM Inhibition of human PI3K p110beta/p85alpha ChEMBL. 22325943
Ki (binding) > 500 nM Inhibition of human PI3K p110gamma ChEMBL. 22325943

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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