Detailed information for compound 1672272

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 392.828 | Formula: C19H14ClFO4S
  • H donors: 1 H acceptors: 2 LogP: 4.64 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)F)Oc1c(=O)cc(oc1c1ccc(cc1)[S@@+](C)[O-])C
  • InChi: 1S/C19H14ClFO4S/c1-11-9-16(22)19(25-17-8-5-13(20)10-15(17)21)18(24-11)12-3-6-14(7-4-12)26(2)23/h3-10H,1-2H3/t26-/m1/s1
  • InChiKey: NFRYFKOUAODBAF-AREMUKBSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase Srms 0.0036 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.019 0.0221 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0053 0.0122
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0065 0.0052 0.0052
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1648 0.2202 0.7404
Loa Loa (eye worm) hypothetical protein 0.0098 0.0097 0.0255
Schistosoma mansoni kinase 0.0043 0.0023 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.0875 0.2939
Brugia malayi C1-like domain containing protein 0.0065 0.0053 0.0175
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0421 0.0536 0.4826
Echinococcus multilocularis casein kinase I alpha 0.0038 0.0016 0.0015
Trypanosoma cruzi Protein kinase B 0.0031 0.0006 0.0017
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0016 0.0015
Plasmodium falciparum protein kinase 5 0.0042 0.0021 0.035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.019 0.0221 0.0742
Entamoeba histolytica hypothetical protein 0.019 0.0221 0.0742
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0091 0.0087 0.1503
Echinococcus multilocularis insulin receptor 0.0111 0.0115 0.0114
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0671 0.0875 0.2941
Plasmodium falciparum protein kinase, putative 0.0031 0.0006 0.009
Schistosoma mansoni vesicular amine transporter 0.0065 0.0053 0.0121
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0016 0.0046
Schistosoma mansoni tyrosine kinase 0.0045 0.0024 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0066 0.0153
Echinococcus multilocularis cyclin dependent kinase 5 0.0042 0.0021 0.002
Loa Loa (eye worm) animal heme peroxidase 0.0047 0.0028 0.0073
Loa Loa (eye worm) hypothetical protein 0.0342 0.0428 0.1136
Trichomonas vaginalis conserved hypothetical protein 0.0449 0.0574 0.1927
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0038 0.0016 0.004
Schistosoma mansoni tyrosine kinase 0.003 0.0005 0.001
Leishmania major phosphatidylinositol kinase related protein, putative 0.02 0.0235 0.0635
Loa Loa (eye worm) SRC-1 0.0065 0.0052 0.0138
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.019 0.0221 0.1985
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.019 0.0221 0.3826
Schistosoma mansoni tyrosine kinase 0.0065 0.0052 0.0121
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0044 0.0024 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0023 0.0052
Echinococcus granulosus casein kinase I alpha 0.0038 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0053 0.0036 0.0083
Giardia lamblia Kinase, NEK 0.0084 0.0078 0.0466
Schistosoma mansoni immunophilin 0.0038 0.0016 0.0035
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0411 0.0522 0.1754
Loa Loa (eye worm) hypothetical protein 0.0057 0.0042 0.0109
Echinococcus granulosus rho-associated protein kinase 1 0.0114 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0027 0.0001 0.0003
Echinococcus granulosus tyrosine protein kinase ABL1 0.0182 0.021 0.021
Schistosoma mansoni serine/threonine protein kinase 0.013 0.014 0.0324
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0126 0.0135 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0132 0.0307
Entamoeba histolytica protein kinase, putative 0.004 0.0018 0.0059
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.0087 0.0292
Loa Loa (eye worm) phosphatidylinositol 3 0.019 0.0221 0.0586
Loa Loa (eye worm) hypothetical protein 0.0253 0.0308 0.0816
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Loa Loa (eye worm) hypothetical protein 0.0075 0.0066 0.0173
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0411 0.0522 0.0522
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0065 0.0053 0.0121
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.3192 0.4299 1
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0028 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0087 0.0202
Echinococcus multilocularis peroxidasin 0.0057 0.0042 0.0041
Brugia malayi casein kinase 1, delta 0.0038 0.0016 0.0051
Echinococcus granulosus aurora kinase A 0.0091 0.0087 0.0087
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0444 0.0567 0.1503
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0044 0.0024 0.0062
Echinococcus granulosus defective proboscis extension response 0.0065 0.0053 0.0052
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0055 0.0038 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Onchocerca volvulus 0.0098 0.0097 0.1117
Echinococcus multilocularis serine:threonine protein kinase N2 0.0135 0.0148 0.0147
Trypanosoma cruzi casein kinase, putative 0.0038 0.0016 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0017 0.0039
Brugia malayi Furin-like cysteine rich region family protein 0.0061 0.0046 0.0153
Plasmodium falciparum calcium-dependent protein kinase 2 0.0038 0.0016 0.0263
Loa Loa (eye worm) hypothetical protein 0.0117 0.0123 0.0324
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0038 0.0016 0.0046
Entamoeba histolytica protein kinase, putative 0.0063 0.005 0.0167
Echinococcus granulosus casein kinase i 0.0038 0.0016 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0087 0.0289
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0056 0.004 0.004
Echinococcus granulosus raf serine:threonine protein kinase 0.003 0.0004 0.0004
Toxoplasma gondii AGC kinase 0.0068 0.0056 0.0551
Brugia malayi protein kinase C II. 0.0056 0.004 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.0875 0.2939
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0004 0.0012
Echinococcus multilocularis cyclin dependent kinase 19 0.0104 0.0105 0.0105
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0421 0.0536 0.1801
Echinococcus granulosus Protein kinase C brain isozyme 0.0056 0.004 0.004
Leishmania major hypothetical protein, conserved 0.2742 0.3688 1
Onchocerca volvulus Slit protein homolog 0.003 0.0005 0.006
Schistosoma mansoni tyrosine kinase 0.0197 0.0232 0.0538
Echinococcus granulosus NDR protein kinase 0.0044 0.0024 0.0023
Entamoeba histolytica serine/threonine protein kinase, putative 0.0027 0.0001 0.0002
Brugia malayi Protein kinase domain containing protein 0.0381 0.0482 0.1618
Brugia malayi serine/threonine-protein kinase 6 0.0091 0.0087 0.0291
Loa Loa (eye worm) hypothetical protein 0.0053 0.0036 0.0095
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.007 0.0059 0.0154
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Loa Loa (eye worm) TK/ALK protein kinase 0.0381 0.0481 0.1277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.0875 0.2939
Entamoeba histolytica protein kinase, putative 0.0028 0.0002 0.0004
Onchocerca volvulus 0.0043 0.0022 0.0259
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0087 0.0289
Echinococcus multilocularis dual specificity testis specific protein kinase 0.014 0.0154 0.0154
Loa Loa (eye worm) blistered cuticle protein 3 0.0032 0.0007 0.0017
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.019 0.0221 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0502 0.0645 0.2167
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0819 0.1076 0.3617
Onchocerca volvulus Peroxidasin homolog 0.0048 0.0029 0.0334
Schistosoma mansoni tyrosine kinase 0.0041 0.002 0.0045
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0844 0.1109 1
Echinococcus granulosus neuroglian 0.0028 0.0002 0.0001
Trichomonas vaginalis STE family protein kinase 0.0116 0.0121 0.0405
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.0052 0.0052
Echinococcus multilocularis cyclin dependent kinase 9 0.0049 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.003 0.0005 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0066 0.0153
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.02 0.0235 0.0686
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.0056 0.0187
Echinococcus granulosus casein kinase I delta 0.0038 0.0016 0.0015
Loa Loa (eye worm) thyroid receptor interactor 0.006 0.0045 0.0117
Echinococcus multilocularis epidermal growth factor receptor 0.0061 0.0046 0.0046
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0065 0.0052 0.0052
Entamoeba histolytica cell division protein kinase 2, putative 0.0042 0.0021 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.01 0.01 0.0292
Brugia malayi Protein kinase domain containing protein 0.0036 0.0012 0.0039
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0065 0.0053 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0023 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.0819 0.1076 0.2854
Brugia malayi Blistered cuticle protein 3 0.0032 0.0007 0.0021
Schistosoma mansoni protein kinase 0.0116 0.0122 0.0282
Echinococcus granulosus casein kinase I delta 0.0038 0.0016 0.0015
Echinococcus granulosus protein kinase shaggy 0.0079 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0053 0.0036 0.0095
Echinococcus multilocularis cyclin dependent kinase 9 0.0043 0.0023 0.0022
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0053 0.0036 0.0316
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0061 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0042 0.0021 0.002
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0065 0.0052 0.0052
Brugia malayi Protein kinase domain containing protein 0.0044 0.0024 0.0078
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0221 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0411 0.0522 0.1384
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0976 0.129 0.4336
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0091 0.0087 0.0229
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0007 0.0021
Trypanosoma cruzi casein kinase, putative 0.0038 0.0016 0.0046
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.019 0.0221 0.0742
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0844 0.1109 0.3729
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0116 0.0121 0.0326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Loa Loa (eye worm) TK protein kinase 0.004 0.0018 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0937 0.3147
Onchocerca volvulus Dual oxidase homolog 0.0032 0.0007 0.008
Schistosoma mansoni protein kinase 0.007 0.0059 0.0135
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0495 0.0636 0.5727
Onchocerca volvulus 0.022 0.0262 0.3036
Schistosoma mansoni serine/threonine kinase 0.0044 0.0024 0.0054
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2216 0.2974 1
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0021 0.0065
Schistosoma mansoni protein kinase 0.0116 0.0122 0.0282
Entamoeba histolytica protein kinase, putative 0.0079 0.0071 0.0238
Onchocerca volvulus 0.0036 0.0012 0.014
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0116 0.0121 0.1085
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0221 0.0264 0.0264
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0039 0.0017 0.0044
Loa Loa (eye worm) hypothetical protein 0.0036 0.0012 0.0031
Echinococcus multilocularis Immunoglobulin 0.0065 0.0053 0.0052
Brugia malayi Protein kinase domain containing protein 0.02 0.0235 0.0788
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0444 0.0567 0.1534
Loa Loa (eye worm) hypothetical protein 0.0065 0.0053 0.0138
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0182 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0449 0.0574 0.1523
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0671 0.0875 0.0874
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0421 0.0536 0.1246
Brugia malayi p70 ribosomal S6 kinase beta 0.0059 0.0045 0.0148
Echinococcus multilocularis dual specificity mitogen activated protein 0.0116 0.0121 0.0121
Echinococcus granulosus protein kinase C gamma type 0.0045 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.026 0.0317 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0024 0.0054
Loa Loa (eye worm) TK protein kinase 0.0056 0.004 0.0105
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0079 0.0071 0.0207
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Echinococcus multilocularis serine:threonine protein kinase N2 0.0091 0.0088 0.0087
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0038 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0051 0.0032 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0095 0.022
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0093 0.0216
Echinococcus multilocularis mitogen activated protein kinase 14 0.01 0.01 0.01
Loa Loa (eye worm) phosphatidylinositol 3 0.0671 0.0875 0.2321
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0061 0.0046 0.0046
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0124 0.0132 0.035
Echinococcus granulosus tyrosine protein kinase Src64B 0.0065 0.0052 0.0052
Brugia malayi Serine/threonine-protein kinase SULU 0.0145 0.0161 0.0538
Loa Loa (eye worm) TK/EGFR protein kinase 0.0061 0.0046 0.0121
Trypanosoma brucei cdc2-related kinase 3 0.0042 0.0021 0.0176
Trypanosoma brucei protein kinase, putative 0.0079 0.0071 0.0631
Echinococcus granulosus tyrosine kinase 0.0056 0.004 0.004
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0038 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0065 0.0053 0.0138
Brugia malayi Protein kinase domain containing protein 0.0137 0.015 0.0504
Brugia malayi cyclin-dependent kinase 9 0.0043 0.0023 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Loa Loa (eye worm) AGC/NDR protein kinase 0.0044 0.0024 0.0062
Plasmodium falciparum calcium-dependent protein kinase 1 0.0038 0.0016 0.0263
Brugia malayi serine/threonine kinase 12 0.0091 0.0087 0.0291
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0002 0.0001
Leishmania major peptidylprolyl isomerase-like protein 0.0038 0.0016 0.0039
Trypanosoma cruzi cdc2-related kinase 3 0.0042 0.0021 0.006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0061 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0317 0.1062
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0038 0.0016 0.0263
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0074 0.0064 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.015 0.0348
Plasmodium falciparum serine/threonine protein kinase KIN 0.0027 0.0001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0773 0.1014 0.3407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0937 0.3147
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0004 0.0009
Brugia malayi FAT domain containing protein 0.026 0.0317 0.1063
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0444 0.0567 0.0566
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0105 0.0243
Echinococcus multilocularis tyrosine protein kinase shark 0.0036 0.0012 0.0012
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0137 0.015 0.0405
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0819 0.1076 0.1075
Brugia malayi EGF-like domain containing protein 0.003 0.0005 0.0016
Echinococcus multilocularis casein kinase I alpha 0.0038 0.0016 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0002 0.0003
Echinococcus granulosus dual specificity 0.0137 0.015 0.015
Echinococcus multilocularis protein KINase family member (kin 25) 0.0064 0.0051 0.0051
Schistosoma mansoni vav2 0.0031 0.0006 0.0013
Onchocerca volvulus 0.0036 0.0012 0.014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.015 0.0504
Brugia malayi Peroxidasin 0.0057 0.0042 0.0138
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0068 0.0056 0.0965
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0038 0.0016 0.0145
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0103 0.0104 0.0104
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0671 0.0875 0.2034
Brugia malayi Protein kinase domain containing protein 0.0036 0.0012 0.0039
Brugia malayi Temporarily assigned gene name protein 59 0.0053 0.0036 0.012
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0138 0.0152 0.0151
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0038 0.0016 0.0145
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0076 0.0066 0.0066
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0065 0.0052 0.0052
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.0052 0.0052
Entamoeba histolytica protein kinase, putative 0.0044 0.0024 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Loa Loa (eye worm) hypothetical protein 0.0812 0.1067 0.283
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0444 0.0567 0.5104
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0068 0.0056 0.0164
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Schistosoma mansoni protein kinase 0.0031 0.0006 0.0012
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0137 0.015 0.1346
Toxoplasma gondii aurora kinase 0.0091 0.0087 0.0863
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0068 0.0056 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0104 0.0241
Loa Loa (eye worm) hypothetical protein 0.0096 0.0094 0.0247
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0053 0.0036 0.0106
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0016 0.0046
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0444 0.0567 0.1317
Onchocerca volvulus 0.003 0.0004 0.0048
Plasmodium falciparum glycogen synthase kinase 3 0.0079 0.0071 0.1225
Brugia malayi Protein kinase domain containing protein 0.0104 0.0105 0.0351
Onchocerca volvulus 0.0663 0.0864 1
Echinococcus granulosus epidermal growth factor receptor 0.0061 0.0046 0.0046
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0068 0.0056 0.0496
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0002 0.0001
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0007 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0004 0.0008
Schistosoma mansoni protein kinase 0.0116 0.0122 0.0282
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Echinococcus multilocularis protein kinase shaggy 0.0079 0.0071 0.0071
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0035 0.0011 0.0011
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0095 0.0093 0.0093
Brugia malayi hypothetical protein 0.0032 0.0007 0.0021
Giardia lamblia GTOR 0.0819 0.1076 0.6442
Echinococcus multilocularis cyclin dependent kinase 7 0.0066 0.0053 0.0053
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0038 0.0016 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0119 0.0276
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0038 0.0016 0.0264
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0444 0.0567 0.0566
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Brugia malayi Protein kinase domain containing protein 0.0053 0.0036 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0819 0.1076 0.3615
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0035 0.0011 0.0011
Echinococcus multilocularis fk506 binding protein 0.0038 0.0016 0.0015
Echinococcus multilocularis epidermal growth factor receptor 0.0061 0.0046 0.0046
Schistosoma mansoni rap gtpase-activating protein 0.0053 0.0036 0.0083
Brugia malayi SRC-1 0.0065 0.0052 0.0174
Schistosoma mansoni tyrosine kinase 0.0045 0.0024 0.0055
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.019 0.0221 0.0221
Echinococcus granulosus mitogen activated protein kinase 14 0.01 0.01 0.01
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0104 0.0105 0.0277
Brugia malayi SH2 domain containing protein 0.0036 0.0012 0.0039
Giardia lamblia Kinase, AGC AKT 0.0071 0.006 0.0357
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0097 0.0095 0.0277
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0116 0.0121 0.0354
Loa Loa (eye worm) transcription factor SMAD2 0.0085 0.0079 0.0207
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0145 0.0161 0.0425
Schistosoma mansoni protein kinase 0.0038 0.0016 0.0035
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.2216 0.2974 1
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0076 0.0066 0.0066
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0042 0.0021 0.0053
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0124 0.0132 0.1532
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0095 0.0093 0.0093
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.026 0.0317 0.0316
Echinococcus multilocularis 0.0085 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0068 0.0056 0.0147
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0096 0.0094 0.0093
Schistosoma mansoni tyrosine kinase 0.0131 0.0141 0.0327
Echinococcus multilocularis neuroglian 0.0028 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0021 0.0047
Entamoeba histolytica hypothetical protein 0.019 0.0221 0.0742
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0079 0.0071 0.0187
Schistosoma mansoni tyrosine kinase 0.0061 0.0046 0.0106
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.019 0.0221 0.2207
Trichomonas vaginalis STE family protein kinase 0.0116 0.0121 0.0405
Loa Loa (eye worm) AUR protein kinase 0.0091 0.0087 0.023
Echinococcus multilocularis tyrosine kinase 0.0036 0.0012 0.0012
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0042 0.0021 0.0053
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0016 0.0015
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0038 0.0016 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Brugia malayi Protein kinase domain containing protein 0.0111 0.0115 0.0384
Giardia lamblia Kinase, CMGC GSK 0.0079 0.0071 0.0423
Brugia malayi serine/threonine protein kinase 6 0.0091 0.0087 0.0291
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0053 0.0036 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0819 0.1076 0.3615
Loa Loa (eye worm) hypothetical protein 0.0142 0.0156 0.0414
Schistosoma mansoni cell adhesion molecule 0.0028 0.0002 0.0002
Echinococcus granulosus protein kinase c iota type 0.0055 0.0038 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0148 0.0342
Echinococcus granulosus activated cdc42 kinase 1 0.0136 0.0149 0.0148
Echinococcus multilocularis cyclin dependent kinase 1 0.0042 0.0021 0.002
Trichomonas vaginalis STE family protein kinase 0.0084 0.0078 0.0259
Entamoeba histolytica hypothetical protein 0.0137 0.015 0.0504
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0065 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0075 0.0066 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0559 0.0723 0.2428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0728 0.0952 0.32
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0452 0.0577 0.0577
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0937 0.3147
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0819 0.1076 0.3136
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0007 0.0017
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.1469 0.1958 0.1958
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.019 0.0221 0.0742
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0038 0.0016 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0071 0.0238
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0093 0.009 0.0238
Toxoplasma gondii FATC domain-containing protein 0.0421 0.0536 0.5364
Schistosoma mansoni fkbp-rapamycin associated protein 0.0411 0.0522 0.1213
Entamoeba histolytica hypothetical protein 0.1824 0.2441 0.821
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0043 0.0023 0.0059
Brugia malayi cyclin-dependent kinase 7 homolog 0.0071 0.0061 0.0202
Onchocerca volvulus 0.0032 0.0007 0.008
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0056 0.004 0.004
Trichomonas vaginalis STE family protein kinase 0.0116 0.0121 0.0405
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0452 0.0577 0.5779
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.019 0.0221 0.074
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0444 0.0567 0.1903
Loa Loa (eye worm) hypothetical protein 0.019 0.0221 0.0586
Brugia malayi Protein kinase domain containing protein 0.0663 0.0864 0.2905
Schistosoma mansoni peroxidasin 0.0042 0.002 0.0046
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0097 0.0095 0.0846
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0819 0.1076 0.2915
Brugia malayi SH2 domain containing protein 0.0036 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0085 0.0079 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0221 0.0265 0.0886
Echinococcus granulosus serine:threonine kinase SAD 1 0.0027 0.0001 0.0001
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0038 0.0016 0.004
Trichomonas vaginalis CK1 family protein kinase 0.0038 0.0016 0.0049
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0053 0.0036 0.0083
Onchocerca volvulus 0.019 0.0221 0.2559
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.2027 0.2716 0.9134
Plasmodium falciparum calcium-dependent protein kinase 3 0.0038 0.0016 0.0263
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0016 0.0015
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0038 0.0016 0.0015
Echinococcus multilocularis activated cdc42 kinase 1 0.0136 0.0149 0.0148
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0097 0.0095 0.0277
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0021 0.0065
Onchocerca volvulus 0.0036 0.0012 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0016 0.0035
Echinococcus multilocularis activin receptor type 0.0289 0.0356 0.0356
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0038 0.0016 0.004
Brugia malayi intracellular kinase 0.0079 0.0071 0.0237
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0174 0.0201 0.0532
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.004 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Onchocerca volvulus 0.0079 0.0071 0.0822
Trypanosoma brucei cdc2-related kinase 1 0.0042 0.0021 0.0176
Loa Loa (eye worm) phosphatidylinositol 3 0.019 0.0221 0.0586
Schistosoma mansoni serine/threonine-protein kinase 0.0031 0.0006 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Loa Loa (eye worm) AUR protein kinase 0.0091 0.0087 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0502 0.0645 0.2167
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.019 0.0221 0.0221
Leishmania major phosphatidylinositol 3-kinase, putative 0.0452 0.0577 0.1563
Brugia malayi protein-tyrosine kinase 0.0056 0.004 0.0133
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2216 0.2974 1
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0055 0.0038 0.01
Echinococcus multilocularis mitogen activated protein kinase 11 0.01 0.01 0.01
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0844 0.1109 0.373
Leishmania major protein kinase A catalytic subunit isoform 2 0.0068 0.0056 0.0149
Brugia malayi probable protein kinase 0.0107 0.0109 0.0366
Leishmania major protein kinase A catalytic subunit 0.0068 0.0056 0.0149
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0079 0.0071 0.0187
Leishmania major phosphatidylinositol 4-kinase, putative 0.019 0.0221 0.0597
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0038 0.0016 0.0015
Brugia malayi MH2 domain containing protein 0.0085 0.0079 0.0263
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0097 0.0095 0.0941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.0875 0.2939
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0016 0.0131
Echinococcus multilocularis tyrosine protein kinase Blk 0.0056 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.004 0.0092
Brugia malayi hypothetical protein 0.0043 0.0022 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0076
Giardia lamblia Hypothetical protein 0.019 0.0221 0.1322
Brugia malayi Protein kinase domain containing protein 0.0036 0.0012 0.0039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0105 0.0106 0.0354
Echinococcus multilocularis roundabout 2 0.0028 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0016 0.0015
Giardia lamblia Kinase, CK1 Casein kinase 0.0038 0.0016 0.0092
Echinococcus granulosus tyrosine protein kinase Src42A 0.0065 0.0052 0.0052
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0671 0.0875 0.255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0773 0.1014 0.3407
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0031 0.0006 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Giardia lamblia Kinase, CMGC CDK 0.0042 0.0021 0.0121
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0819 0.1076 0.3617
Onchocerca volvulus Peroxidasin homolog 0.0047 0.0028 0.0325
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0124 0.0132 0.035
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0819 0.1076 0.2501
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0091 0.0087 0.0292
Echinococcus multilocularis aurora kinase A 0.0091 0.0087 0.0087
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0097 0.0095 0.0277
Brugia malayi protein C17H12.11 0.0043 0.0022 0.0073
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0844 0.1109 0.3234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0552 0.0713 0.2395
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.0052 0.0052
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0065 0.0052 0.0052
Plasmodium vivax glycogen synthase kinase 3, putative 0.0079 0.0071 0.1225
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0038 0.0016 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Plasmodium vivax casein kinase 1, putative 0.0038 0.0016 0.0266
Onchocerca volvulus 0.0058 0.0042 0.0489
Brugia malayi Fes/CIP4 homology domain containing protein 0.006 0.0045 0.0149
Leishmania major protein kinase, putative 0.0038 0.0016 0.0039
Echinococcus multilocularis cyclin dependent kinase 1 0.0042 0.0021 0.002
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0079 0.0071 0.0071
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0314 0.039 0.1035
Echinococcus granulosus cyclin dependent kinase 1 0.0042 0.0021 0.002
Schistosoma mansoni protein kinase C mu 0.0065 0.0053 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0091 0.0087 0.0087
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0444 0.0567 0.1905
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0053 0.0036 0.0036
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0038 0.0016 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.2553 0.343 1
Trypanosoma cruzi aurora B kinase, putative 0.0091 0.0087 0.0254
Onchocerca volvulus Chorion peroxidase homolog 0.0032 0.0007 0.008
Entamoeba histolytica protein kinase, putative 0.0063 0.005 0.0167
Echinococcus granulosus roundabout 2 0.0093 0.009 0.009
Echinococcus multilocularis expressed conserved protein 0.0058 0.0042 0.0042
Echinococcus granulosus tyrosine protein kinase shark 0.0036 0.0012 0.0012
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.003 0.0004 0.001
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Schistosoma mansoni tyrosine kinase 0.0089 0.0085 0.0196
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.019 0.0221 0.3826
Loa Loa (eye worm) hypothetical protein 0.0068 0.0056 0.0147
Loa Loa (eye worm) hypothetical protein 0.0126 0.0135 0.0356
Trypanosoma brucei rac serine-threonine kinase, putative 0.0063 0.005 0.044
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0114 0.0118 0.0118
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0079 0.0071 0.0164
Echinococcus multilocularis serine:threonine protein kinase 38 0.0044 0.0024 0.0023
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0031 0.0006 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0235 0.0283 0.0948
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0031 0.0006 0.0017
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0091 0.0087 0.0292
Brugia malayi putative serine/threonine kinase SADA gamma 0.0027 0.0001 0.0002
Loa Loa (eye worm) CAMK protein kinase 0.003 0.0004 0.001
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0068 0.0056 0.0551
Trypanosoma cruzi cdc2-related kinase 1 0.0042 0.0021 0.006
Brugia malayi P38 map kinase family protein 2 0.01 0.01 0.0335
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0036 0.0012 0.0039
Echinococcus granulosus peroxidasin 0.0057 0.0042 0.0041
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0038 0.0016 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Loa Loa (eye worm) AGC/AKT protein kinase 0.0063 0.005 0.0131
Schistosoma mansoni atypical protein kinase C 0.0055 0.0038 0.0088
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0071 0.006 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0421 0.0536 0.1799
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0145 0.0161 0.016
Plasmodium falciparum calcium-dependent protein kinase 4 0.0038 0.0016 0.0263
Schistosoma mansoni phosphatidylinositol 4-kinase 0.019 0.0221 0.0513
Onchocerca volvulus 0.0032 0.0007 0.008
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0038 0.0016 0.0263
Schistosoma mansoni tyrosine kinase 0.0111 0.0115 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0221 0.0265 0.0886
Loa Loa (eye worm) AGC/PKA protein kinase 0.0068 0.0056 0.0148
Echinococcus granulosus titin 0.003 0.0004 0.0004
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0332 0.0414 0.1098
Brugia malayi Protein kinase domain containing protein 0.0042 0.0021 0.0067
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0145 0.0161 0.016
Plasmodium vivax calcium-dependent protein kinase, putative 0.0038 0.0016 0.0263
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0065 0.0052 0.0052
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0002 0.0003
Trichomonas vaginalis CK1 family protein kinase 0.0038 0.0016 0.0049
Toxoplasma gondii AGC kinase 0.0068 0.0056 0.0551
Onchocerca volvulus 0.0036 0.0012 0.014
Echinococcus multilocularis protein kinase c epsilon type 0.0056 0.004 0.004
Echinococcus multilocularis tyrosine protein kinase Abl 0.01 0.01 0.01
Echinococcus granulosus expressed conserved protein 0.0058 0.0042 0.0042
Echinococcus multilocularis Zinc finger, PHD finger 0.0452 0.0577 0.0577
Mycobacterium leprae conserved hypothetical protein 0.019 0.0221 0.5
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0819 0.1076 0.9695
Echinococcus multilocularis 0.0054 0.0037 0.0037
Onchocerca volvulus 0.0032 0.0007 0.008
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.01 0.01 0.0292
Entamoeba histolytica protein kinase , putative 0.0091 0.0087 0.0292
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0068 0.0056 0.0965
Brugia malayi Cam kinase protein 1 0.0038 0.0016 0.0051
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.0052 0.0052
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0103 0.0104 0.0275
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0036 0.0012 0.0012
Echinococcus granulosus slit 2 protein 0.003 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0221 0.0264 0.0887
Schistosoma mansoni nephrin 0.0083 0.0077 0.0178
Echinococcus multilocularis protein kinase c iota type 0.0055 0.0038 0.0038
Entamoeba histolytica protein kinase, putative 0.0091 0.0087 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0002 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0016 0.0035
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.028 0.0345 0.3099
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0027 0 0.0001
Schistosoma mansoni cell adhesion molecule 0.0078 0.0069 0.016
Schistosoma mansoni protein kinase 0.0116 0.0121 0.0281
Echinococcus granulosus c src tyrosine kinase 0.0045 0.0024 0.0024
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0033 0.0008 0.0023
Brugia malayi bone morphogenetic protein type 1 receptor 0.007 0.0059 0.0195
Onchocerca volvulus Tyrosine kinase homolog 0.0255 0.031 0.3582
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.2216 0.2974 1
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0116 0.0121 0.0407
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0095 0.0093 0.0312
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0102 0.0102 0.0343
Entamoeba histolytica protein kinase, putative 0.0059 0.0045 0.0149
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1648 0.2202 0.7404
Brugia malayi casein kinase I 0.0038 0.0016 0.0051
Schistosoma mansoni tyrosine kinase 0.0065 0.0052 0.0121
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0091 0.0087 0.0292
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0116 0.0122 0.0121
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.2216 0.2974 0.8668
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0444 0.0567 0.1652
Echinococcus granulosus cyclin dependent kinase 19 0.0104 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0232 0.0279 0.0738
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0038 0.0016 0.0051
Brugia malayi Hr1 repeat family protein 0.0135 0.0148 0.0495
Loa Loa (eye worm) AUR protein kinase 0.0091 0.0087 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0762 0.0998 0.3355
Loa Loa (eye worm) hypothetical protein 0.0028 0.0002 0.0003
Schistosoma mansoni tyrosine kinase 0.0036 0.0012 0.0027
Echinococcus multilocularis serine threonine protein kinase 0.0045 0.0025 0.0025
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0671 0.0875 0.7882
Entamoeba histolytica casein kinase, putative 0.0038 0.0016 0.0052
Trichomonas vaginalis immunophilin, putative 0.0038 0.0016 0.0049
Loa Loa (eye worm) phosphatidylinositol 3 0.0654 0.0852 0.2261
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0137 0.015 0.0398
Schistosoma mansoni tyrosine kinase 0.0041 0.002 0.0045
Schistosoma mansoni titin 0.003 0.0004 0.0008
Leishmania major casein kinase, putative 0.0038 0.0016 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0095 0.022
Plasmodium vivax hypothetical protein 0.019 0.0221 0.3826
Giardia lamblia Kinase, NEK 0.0084 0.0078 0.0466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0502 0.0645 0.2167
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0091 0.0087 0.0087
Brugia malayi protein unc-22 0.003 0.0004 0.0012
Brugia malayi Protein kinase domain containing protein 0.0136 0.0149 0.0498
Loa Loa (eye worm) hypothetical protein 0.0064 0.0051 0.0134
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0038 0.0016 0.0263
Loa Loa (eye worm) hypothetical protein 0.0068 0.0056 0.0148
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0053 0.0036 0.0036
Trypanosoma brucei aurora B kinase 0.0091 0.0087 0.0776
Echinococcus multilocularis rho associated protein kinase 0.0114 0.0119 0.0119
Giardia lamblia Kinase, NEK 0.0084 0.0078 0.0466
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0116 0.0121 0.0321
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.026 0.0317 0.0316
Echinococcus granulosus contactin 0.0028 0.0002 0.0001
Toxoplasma gondii target of rapamycin (TOR), putative 0.0762 0.0998 1
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0038 0.0016 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0095 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0522 0.1752
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0137 0.015 0.0438
Echinococcus multilocularis TGF beta receptor type 1 0.0062 0.0048 0.0048
Echinococcus granulosus activated cdc42 kinase 1 0.0136 0.0149 0.0148
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0078 0.007 0.0184
Echinococcus granulosus fibroblast growth factor receptor 4 0.0089 0.0085 0.0084
Echinococcus granulosus TGF-beta receptor type-1 0.0062 0.0048 0.0048
Echinococcus multilocularis tyrosine protein kinase HCK 0.004 0.0018 0.0018
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.01 0.01 0.0269
Echinococcus granulosus casein kinase I alpha 0.0038 0.0016 0.0015
Echinococcus multilocularis dual specificity protein kinase clk2 0.0097 0.0095 0.0095
Trypanosoma brucei protein kinase, putative 0.0031 0.0006 0.0041
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0819 0.1076 0.2915
Loa Loa (eye worm) gastrulation defective protein 1 0.0092 0.0089 0.0235
Brugia malayi Fibronectin type III domain containing protein 0.0068 0.0056 0.0187
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0038 0.0016 0.0015
Giardia lamblia Kinase, CAMK CAMKL 0.0033 0.0009 0.005
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0114 0.0118 0.0118
Loa Loa (eye worm) IKK protein kinase 0.0663 0.0864 0.2293
Loa Loa (eye worm) hypothetical protein 0.003 0.0005 0.0012
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.019 0.0221 0.3826
Echinococcus granulosus serine:threonine protein kinase N2 0.0135 0.0148 0.0147
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0044 0.0024 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0063 0.005 0.0164
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0093 0.009 0.009
Loa Loa (eye worm) TK protein kinase 0.0105 0.0106 0.028
Echinococcus granulosus Vam6:Vps39 protein 0.0053 0.0036 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0773 0.1014 0.3407
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0093 0.009 0.0238
Schistosoma mansoni hypothetical protein 0.0058 0.0042 0.0097
Toxoplasma gondii AGC kinase 0.0059 0.0045 0.0436
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0068 0.0056 0.0147
Loa Loa (eye worm) hypothetical protein 0.0043 0.0022 0.0058
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0581 0.0753 0.451
Entamoeba histolytica protein kinase, putative 0.0038 0.0016 0.0051
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0819 0.1076 0.3617
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.019 0.0221 0.3826
Plasmodium falciparum casein kinase 1 0.0038 0.0016 0.0266
Echinococcus multilocularis c src tyrosine kinase 0.0045 0.0024 0.0024
Plasmodium vivax serine/threonine kinase-1, putative 0.0097 0.0095 0.1639
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0056 0.004 0.004
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0452 0.0577 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0012 0.004
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.013 0.014 0.014
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0071 0.0235
Echinococcus multilocularis tyrosine protein kinase Srms 0.0056 0.004 0.004
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.019 0.0221 0.0645
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0444 0.0567 0.5673
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0021
Loa Loa (eye worm) phosphatidylinositol kinase 0.019 0.0221 0.0586
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0002 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.004 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0021 0.0065
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0079 0.0071 0.0701
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Echinococcus multilocularis raf serine:threonine protein kinase 0.003 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0055 0.0038 0.0126
Echinococcus granulosus protein kinase 0.0054 0.0037 0.0037
Echinococcus granulosus dual specificity protein kinase clk2 0.0097 0.0095 0.0095
Leishmania major fk506-binding protein 1-like protein 0.0038 0.0016 0.0039
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0671 0.0875 0.0874
Echinococcus granulosus roundabout 2 0.0028 0.0002 0.0001
Echinococcus granulosus cyclin dependent kinase 0.0042 0.0021 0.002
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0138 0.0152 0.0151
Echinococcus granulosus cyclin dependent kinase 9 0.0049 0.003 0.003
Trichomonas vaginalis fk506-binding protein, putative 0.0038 0.0016 0.0049
Schistosoma mansoni tyrosine kinase 0.0165 0.0188 0.0437
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0703 0.0919 0.0918
Brugia malayi hypothetical protein 0.0145 0.0161 0.0538
Brugia malayi serine/threonine-protein kinase PAK 7 0.0141 0.0155 0.0519
Leishmania major hypothetical protein, unknown function 0.019 0.0221 0.0597
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0027 0.0001 0.0002
Plasmodium vivax hypothetical protein, conserved 0.019 0.0221 0.3826
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0095 0.0093 0.0246
Trypanosoma cruzi casein kinase, putative 0.0038 0.0016 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.019 0.0221 0.0586
Onchocerca volvulus 0.0053 0.0036 0.0419
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0097 0.0095 0.0251
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.019 0.0221 0.0645
Echinococcus granulosus dual specificity testis-specific protein kinase 0.014 0.0154 0.0154
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0044 0.0024 0.0023
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0844 0.1109 0.373
Echinococcus multilocularis casein kinase I delta 0.0038 0.0016 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0056 0.0129
Leishmania major protein kinase, putative 0.0097 0.0095 0.0254
Echinococcus granulosus tyrosine protein kinase Lyn 0.0077 0.0068 0.0068
Echinococcus multilocularis serine protein kinase ATM 0.0421 0.0536 0.0536
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0079 0.0071 0.019
Echinococcus granulosus activin receptor type 0.0289 0.0356 0.0356
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0064 0.0051 0.0051
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0084 0.0078 0.1349
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0038 0.0016 0.0015
Schistosoma mansoni nephrin 0.0028 0.0002 0.0002
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.019 0.0221 0.0513
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0844 0.1109 0.3729
Brugia malayi hypothetical protein 0.0068 0.0056 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0671 0.0875 0.2939
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0031 0.0006 0.0041
Echinococcus multilocularis dual specificity 0.0137 0.015 0.015
Loa Loa (eye worm) AGC/PKA protein kinase 0.0068 0.0056 0.0148
Echinococcus granulosus cyclin dependent kinase 5 0.0042 0.0021 0.002
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0053 0.0036 0.0093
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0059 0.0045 0.0117
Echinococcus granulosus titin 0.003 0.0004 0.0004
Brugia malayi Tyrosine-protein kinase abl-1 0.009 0.0086 0.0289
Echinococcus granulosus Immunoglobulin 0.0065 0.0053 0.0052
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0076
Giardia lamblia Aurora kinase 0.0091 0.0087 0.052
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.1256 0.167 1
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0054 0.0037 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0936 0.3146
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.019 0.0221 0.0221
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0028 0.0002 0.0004
Brugia malayi Protein kinase domain containing protein 0.0044 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0108 0.0111 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Echinococcus granulosus cyclin dependent kinase 7 0.0066 0.0053 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0087 0.0289
Echinococcus multilocularis rac serine:threonine kinase 0.0031 0.0006 0.0005
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0452 0.0577 0.1939
Schistosoma mansoni tyrosine kinase 0.0064 0.0051 0.0117
Onchocerca volvulus 0.0114 0.0119 0.138
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0065 0.0052 0.0052
Entamoeba histolytica casein kinase 1, putative 0.0038 0.0016 0.0052
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0038 0.0016 0.0051
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0007 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0056 0.0129
Brugia malayi Stress-activated protein kinase jnk-1 0.0174 0.0201 0.0673
Trypanosoma cruzi target of rapamycin kinase 3 0.0773 0.1014 0.2956
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0036 0.0012 0.0012
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0065 0.0052 0.0052
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.3192 0.4299 0.4299
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0038 0.0016 0.0046
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0103 0.0104 0.0104
Plasmodium falciparum protein serine/threonine kinase-1 0.0097 0.0095 0.1639
Echinococcus multilocularis casein kinase i 0.0038 0.0016 0.0015
Echinococcus multilocularis neuroglian 0.0081 0.0074 0.0073
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0844 0.1109 0.3729
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.039 0.1311
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0038 0.0016 0.004
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0042 0.0021 0.0195
Echinococcus granulosus serine protein kinase ATM 0.0421 0.0536 0.0536
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0671 0.0875 0.7882
Trypanosoma cruzi cdc2-related kinase 3 0.0042 0.0021 0.006
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.019 0.0221 0.1985
Entamoeba histolytica protein kinase, putative 0.0091 0.0087 0.0292
Plasmodium falciparum calcium-dependent protein kinase 5 0.0038 0.0016 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0819 0.1076 0.3615
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0028 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0201 0.0466
Schistosoma mansoni neuroglian 0.0028 0.0002 0.0002
Plasmodium falciparum phosphatidylinositol 4-kinase 0.019 0.0221 0.3826
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0066 0.0053 0.014
Echinococcus multilocularis slit 2 protein 0.003 0.0005 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0411 0.0522 0.1754
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1472 0.1963 0.66
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0671 0.0875 0.237
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.019 0.0221 0.0645
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0012 0.0031
Giardia lamblia Phosphatidylinositol 4-kinase 0.019 0.0221 0.1322
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0053 0.0036 0.0083
Entamoeba histolytica hypothetical protein 0.0421 0.0536 0.1801
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0111
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1012 0.1339 0.4501
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0078 0.007 0.0234
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0411 0.0522 0.1521
Echinococcus granulosus serine/threonine protein kinase 0.0031 0.0006 0.0005
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0819 0.1076 0.1075
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0053 0.0036 0.0035
Schistosoma mansoni tyrosine kinase 0.0044 0.0024 0.0055
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0773 0.1014 0.2748
Echinococcus multilocularis Immunoglobulin 0.0065 0.0053 0.0052
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.019 0.0221 0.0513
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0089 0.0085 0.0084
Schistosoma mansoni tyrosine kinase 0.0061 0.0046 0.0106
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0444 0.0567 0.1905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0937 0.3147
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0042 0.0021 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0016 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0021 0.0047
Schistosoma mansoni peroxidasin 0.0032 0.0007 0.0015
Loa Loa (eye worm) TK/ABL protein kinase 0.0182 0.021 0.0557
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0038 0.0016 0.004
Loa Loa (eye worm) hypothetical protein 0.0054 0.0037 0.0096
Giardia lamblia Kinase, AGC PKA 0.0068 0.0056 0.0334
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0819 0.1076 0.9695
Loa Loa (eye worm) hypothetical protein 0.0053 0.0036 0.0095
Giardia lamblia Kinase, CMGC CDK 0.0042 0.0021 0.0121
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0078 0.0259
Brugia malayi Protein kinase domain containing protein 0.007 0.0059 0.0195
Echinococcus granulosus protein kinase c epsilon type 0.0056 0.004 0.004
Schistosoma mansoni protein kinase 0.0091 0.0087 0.0202
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.09 0.1187 0.399
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0038 0.0016 0.0091
Echinococcus granulosus protein tyrosine kinase 0.0197 0.0232 0.0231
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0038 0.0016 0.0091
Echinococcus granulosus roundabout 2 0.0028 0.0002 0.0001
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0141 0.0155 0.041
Schistosoma mansoni protein kinase 0.014 0.0154 0.0358
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0042 0.0021 0.0053
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0089 0.0085 0.0084
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0089 0.0085 0.0084
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0084 0.0078 0.0773
Loa Loa (eye worm) hypothetical protein 0.0043 0.0022 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0024 0.0054
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0075 0.0065 0.0174
Echinococcus granulosus tyrosine protein kinase Blk 0.0056 0.004 0.004
Echinococcus multilocularis transfer RNA-Thr 0.0136 0.0149 0.0148
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.2216 0.2974 0.8668
Echinococcus granulosus tyrosine protein kinase HCK 0.004 0.0018 0.0018
Echinococcus granulosus insulin receptor 0.0111 0.0115 0.0114
Brugia malayi Tyrosine-protein kinase abl-1 0.01 0.01 0.0335
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0093 0.009 0.0301
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Leishmania major phosphatidylinositol kinase, putative 0.019 0.0221 0.0597
Onchocerca volvulus 0.0103 0.0104 0.1198
Echinococcus granulosus epidermal growth factor receptor 0.0061 0.0046 0.0046
Schistosoma mansoni tyrosine kinase 0.0061 0.0046 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0053 0.0122
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0044 0.0024 0.0023
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0654 0.0852 0.2484
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0421 0.0536 0.1562
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0065 0.0053 0.0052
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.2216 0.2974 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0097 0.0095 0.0846
Brugia malayi Protein kinase domain containing protein 0.0063 0.005 0.0166
Onchocerca volvulus Peroxidase homolog 0.0032 0.0007 0.008
Echinococcus multilocularis cyclin dependent kinase 0.0042 0.0021 0.002
Trichomonas vaginalis AGC family protein kinase 0.005 0.0031 0.0101
Trichomonas vaginalis CK1 family protein kinase 0.0038 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0091 0.0087 0.0229
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0444 0.0567 0.1903
Plasmodium vivax protein kinase Crk2 0.0042 0.0021 0.035
Echinococcus granulosus neuroglian 0.0081 0.0074 0.0073
Brugia malayi Protein kinase domain containing protein 0.0097 0.0095 0.0318
Schistosoma mansoni protein kinase 0.0054 0.0037 0.0085
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0116 0.0122 0.0121
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0033 0.0009 0.0144
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0936 0.3146
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.013 0.014 0.037
Echinococcus multilocularis mitogen activated protein kinase 14 0.01 0.01 0.01
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.019 0.0221 0.0742
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0174 0.0201 0.02
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0055 0.0038 0.01
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0065
Echinococcus multilocularis casein kinase I alpha 0.0038 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Giardia lamblia Kinase, CAMK CAMKL 0.0033 0.0009 0.005
Echinococcus multilocularis death associated protein kinase 1 0.0586 0.0759 0.0759
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0904 0.1191 0.277
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0042 0.0021 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0522 0.1752
Loa Loa (eye worm) hypothetical protein 0.0098 0.0097 0.0255
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0007 0.0021
Brugia malayi hypothetical protein 0.0036 0.0012 0.0039
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0068 0.0056 0.0164
Brugia malayi Animal haem peroxidase family protein 0.0047 0.0028 0.0093
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0102 0.0102 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.019 0.0221 0.074
Echinococcus granulosus TGF beta receptor type 1 0.0062 0.0048 0.0048
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0075 0.0066 0.0065
Schistosoma mansoni immunophilin 0.0038 0.0016 0.0035
Brugia malayi Protein kinase domain containing protein 0.0332 0.0414 0.1391
Schistosoma mansoni cell adhesion molecule 0.0028 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.026 0.0317 0.0839
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0045 0.0024 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0056 0.0185
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0232 0.0279 0.0812
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0819 0.1076 0.3136
Echinococcus multilocularis serine:threonine protein kinase N2 0.0044 0.0024 0.0023
Schistosoma mansoni immunophilin 0.0033 0.0009 0.0019
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0068 0.0056 0.0496
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0452 0.0577 0.1342
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0041 0.002 0.0045
Loa Loa (eye worm) hypothetical protein 0.0098 0.0097 0.0255
Schistosoma mansoni protein kinase 0.0107 0.0109 0.0253
Echinococcus granulosus serine:threonine protein kinase N2 0.0091 0.0088 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0192 0.0445
Loa Loa (eye worm) TK/ROR protein kinase 0.0053 0.0036 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0513 0.0661 0.222
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0671 0.0875 0.255
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0124 0.0132 0.0132
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.019 0.0221 0.2207
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Loa Loa (eye worm) TK/INSR protein kinase 0.0111 0.0115 0.0303
Trypanosoma brucei casein kinase I, isoform 2 0.0038 0.0016 0.0132
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0065 0.0052 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0716 0.0936 0.3146
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.3192 0.4299 0.4299
Echinococcus multilocularis mitogen activated protein kinase 11 0.01 0.01 0.01
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.0052 0.0052
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0007 0.0021
Trypanosoma cruzi casein kinase, putative 0.0038 0.0016 0.0046
Trypanosoma cruzi casein kinase, putative 0.0038 0.0016 0.0046
Leishmania major phosphatidylinositol 3-kinase, putative 0.0671 0.0875 0.237
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0773 0.1014 0.9139
Onchocerca volvulus 0.0036 0.0012 0.014
Schistosoma mansoni protein kinase 0.0221 0.0264 0.0614
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.013 0.014 0.014
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0444 0.0567 0.1652
Schistosoma mansoni hypothetical protein 0.019 0.0221 0.0513
Schistosoma mansoni vam6/vps39 related 0.0053 0.0036 0.0083
Mycobacterium tuberculosis Conserved hypothetical protein 0.019 0.0221 0.5
Brugia malayi hypothetical protein 0.0053 0.0036 0.012
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0137 0.015 0.0438
Echinococcus multilocularis roundabout 2 0.0028 0.0002 0.0001
Leishmania major protein kinase A catalytic subunit isoform 1 0.0068 0.0056 0.0149
Echinococcus granulosus dual specificity mitogen activated protein 0.0116 0.0121 0.0121
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0097 0.0095 0.0277
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0773 0.1014 0.3407
Echinococcus multilocularis roundabout 2 0.0093 0.009 0.009
Onchocerca volvulus Peroxidase homolog 0.0032 0.0007 0.008
Entamoeba histolytica protein kinase, putative 0.0039 0.0017 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0048 0.0029 0.0094
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0027 0.0001 0.0001
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0028 0.0093
Brugia malayi Protein kinase domain containing protein 0.0037 0.0015 0.0047
Brugia malayi cell division control protein 2 homolog 0.0042 0.0021 0.0067
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0071 0.0235
Brugia malayi Protein kinase domain containing protein 0.013 0.014 0.0469
Loa Loa (eye worm) phosphatidylinositol 3 0.0197 0.0232 0.0614
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0006 0.0018
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0068 0.0056 0.0147
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0038 0.0016 0.004
Leishmania major protein kinase, putative 0.0097 0.0095 0.0254
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0074 0.0064 0.0064
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0062 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0102 0.0237
Echinococcus granulosus casein kinase I alpha 0.0038 0.0016 0.0015
Loa Loa (eye worm) MH2 domain-containing protein 0.0085 0.0079 0.0207
Echinococcus multilocularis protein tyrosine kinase 0.0197 0.0232 0.0231
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0053 0.0036 0.0106
Brugia malayi SH2 domain containing protein 0.0253 0.0308 0.1034
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.01 0.01 0.0894
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0068 0.0056 0.0187
Loa Loa (eye worm) hypothetical protein 0.0066 0.0053 0.0139
Echinococcus granulosus mitogen activated protein kinase 11 0.01 0.01 0.01
Giardia lamblia Kinase, STE STE20 0.0116 0.0121 0.0725
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.019 0.0221 0.0221
Loa Loa (eye worm) TK/FAK protein kinase 0.02 0.0235 0.0622
Leishmania major protein kinase, putative 0.0031 0.0006 0.0012
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0027 0.0001 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0038 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0022 0.0058
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.0052 0.0052
Schistosoma mansoni serine/threonine-protein kinase 0.0031 0.0006 0.0012
Echinococcus granulosus c-Jun N-terminal kinases 0.0174 0.0201 0.02
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.019 0.0221 0.074
Loa Loa (eye worm) AGC/PKN protein kinase 0.0135 0.0148 0.0391
Entamoeba histolytica protein kinase, putative 0.0137 0.015 0.0504
Echinococcus granulosus hypothetical protein 0.0085 0.0079 0.0079
Schistosoma mansoni protein kinase 0.0062 0.0048 0.0111
Schistosoma mansoni tyrosine kinase 0.0111 0.0115 0.0266
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0038 0.0016 0.0051
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.01 0.01 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.019 0.0221 0.074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0012 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0728 0.0952 0.32
Leishmania major protein kinase, putative 0.0091 0.0087 0.0233
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0044 0.0024 0.0023
Echinococcus granulosus tyrosine kinase 0.0036 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0025 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0161 0.0372
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0038 0.0016 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0071 0.0238
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.019 0.0221 0.0645
Giardia lamblia Kinase, CMGC CLK 0.0097 0.0095 0.0566
Entamoeba histolytica protein kinase rad3, putative 0.0411 0.0522 0.1754
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0411 0.0522 0.0522
Onchocerca volvulus 0.019 0.0221 0.2559
Echinococcus multilocularis titin 0.003 0.0004 0.0004
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0056 0.0056
Echinococcus multilocularis casein kinase I delta 0.0038 0.0016 0.0015
Loa Loa (eye worm) phosphatidylinositol 3 0.2801 0.3767 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0031 0.0006 0.0018
Brugia malayi Protein kinase domain containing protein 0.0036 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0136 0.0149 0.0393
Trichomonas vaginalis PIKK family atypical protein kinase 0.0773 0.1014 0.3407
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0444 0.0567 0.1905
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0038 0.0016 0.0131
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0007 0.0017
Plasmodium falciparum NIMA related kinase 1 0.0084 0.0078 0.1349
Giardia lamblia Kinase, CMGC GSK 0.0079 0.0071 0.0423
Onchocerca volvulus 0.0038 0.0016 0.0182
Loa Loa (eye worm) hypothetical protein 0.0038 0.0016 0.004
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.1469 0.1958 0.1958
Echinococcus granulosus twitchin 0.0092 0.0089 0.0089
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0449 0.0574 0.5746
Toxoplasma gondii casein kinase I 0.0038 0.0016 0.0146
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0124 0.0132 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0087 0.0289
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0038 0.0016 0.0035
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0068 0.0056 0.0496
Loa Loa (eye worm) FKBP5 protein 0.0038 0.0016 0.004
Schistosoma mansoni protein kinase 0.014 0.0154 0.0358
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0038 0.0016 0.0145
Loa Loa (eye worm) hypothetical protein 0.1469 0.1958 0.5198
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0221 0.0264 0.07
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0065 0.0053 0.0121
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0065 0.0053 0.0138
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0452 0.0577 1
Onchocerca volvulus 0.0036 0.0012 0.014
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0056 0.004 0.004
Trypanosoma cruzi cdc2-related kinase 1 0.0042 0.0021 0.006
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0033 0.0009 0.0008
Echinococcus multilocularis 0.019 0.0221 0.0221
Entamoeba histolytica protein kinase, putative 0.0137 0.015 0.0504
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0093 0.009 0.009
Brugia malayi Protein kinase domain containing protein 0.0124 0.0132 0.0443
Echinococcus granulosus cyclin dependent kinase 9 0.0043 0.0023 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0012 0.0031
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0031 0.0006 0.0016
Onchocerca volvulus 0.0054 0.0037 0.0427
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0068 0.0056 0.0164
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.019 0.0221 0.2207
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.739 1 1
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0124 0.0132 0.0443
Plasmodium falciparum serine/threonine protein kinase, putative 0.0091 0.0087 0.1503
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0033 0.0009 0.0008
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0056 0.004 0.0105
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1824 0.2441 0.821
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0079 0.0071 0.0071

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.47 uM Inhibition of COX2 in human whole blood ChEMBL. 16647258
Selectivity ratio (binding) = 30 Selectivity ratio for COX2 over COX1 in human whole blood ChEMBL. 16647258

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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