TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 537.513 | Formula: C26H18F3N5O3S
H donors: 1 H acceptors: 2 LogP: 5.02 Rotable bonds: 8
Rule of 5 violations (Lipinski): 2
SMILES: COc1ccc(cc1)c1nn2c(SCC(=O)Nc3ccccc3C(F)(F)F)nc3c(c2nc1=O)cccc3
InChi: 1S/C26H18F3N5O3S/c1-37-16-12-10-15(11-13-16)22-24(36)32-23-17-6-2-4-8-19(17)31-25(34(23)33-22)38-14-21(35)30-20-9-5-3-7-18(20)26(27,28)29/h2-13H,14H2,1H3,(H,30,35)
InChiKey: BYYXROXNKZOHIL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	hypothetical protein	0.0044	0.0174	0.0174
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.005	0.0203	1
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0036	0.0135	0.0135
Toxoplasma gondii	hypothetical protein	0.0044	0.0174	0.5424
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0135	0.0129
Schistosoma mansoni	centaurin alpha	0.0044	0.0174	0.0174
Brugia malayi	latrophilin 2 splice variant baaae	0.0036	0.0138	0.044
Brugia malayi	hypothetical protein	0.0244	0.1172	0.3916
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.001	0.0007	0.0007
Echinococcus granulosus	FTZ F1 alpha	0.001	0.0007	0.0007
Echinococcus multilocularis	actin binding protein anillin	0.0044	0.0174	0.0174
Echinococcus multilocularis	cpg binding protein	0.0032	0.0118	0.0118
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Mycobacterium leprae	Probable lipase LipE	0.0036	0.0135	0.5
Loa Loa (eye worm)	oxysterol binding protein	0.0044	0.0174	0.0168
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0044	0.0174	0.1379
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0044	0.0174	0.0174
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0044	0.0174	0.0174
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0017	0.004	0.0033
Echinococcus multilocularis	Pleckstrin y	0.0044	0.0174	0.0174
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Onchocerca volvulus	Protein melted homolog	0.0044	0.0174	0.1379
Schistosoma mansoni	regulator of G protein signaling	0.0244	0.1172	0.1172
Schistosoma mansoni	serine/threonine-protein kinase	0.005	0.0203	0.0203
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0031	0.0109	0.0102
Trypanosoma cruzi	PH domain containing protein, putative	0.0044	0.0174	0.7586
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Entamoeba histolytica	p21-activated kinase	0.005	0.0203	0.0293
Plasmodium vivax	hypothetical protein, conserved	0.0044	0.0174	0.7586
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0017	0.004	0.004
Schistosoma mansoni	cpg binding protein	0.0031	0.0109	0.0109
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0135	0.0129
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0044	0.0174	0.1379
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0036	0.0135	0.5
Schistosoma mansoni	zinc finger protein	0.0044	0.0174	0.0174
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.001	0.0007	0.0007
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0184	0.0184
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.005	0.0203	1
Plasmodium falciparum	calcium-dependent protein kinase 7	0.005	0.0203	1
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Schistosoma mansoni	dynamin	0.0044	0.0174	0.0174
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0244	0.1172	0.9555
Echinococcus granulosus	myotubularin protein 13	0.0044	0.0174	0.0174
Onchocerca volvulus		0.0036	0.0135	0.106
Schistosoma mansoni	myotubularin-related protein	0.0044	0.0174	0.0174
Echinococcus granulosus	pleckstrin y domain containing family A	0.0044	0.0174	0.0174
Entamoeba histolytica	hypothetical protein	0.005	0.0203	0.0293
Brugia malayi	Syntrophin-1	0.0044	0.0174	0.0563
Schistosoma mansoni	dynamin	0.0044	0.0174	0.0174
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Schistosoma mansoni	hypothetical protein	0.0044	0.0174	0.0174
Schistosoma mansoni	axis inhibition protein axin	0.0244	0.1172	0.1172
Echinococcus granulosus	cytohesin 1	0.0044	0.0174	0.0174
Echinococcus granulosus	axis inhibition protein axin	0.0244	0.1172	0.1172
Entamoeba histolytica	PH domain containing protein kinase, putative	0.005	0.0203	0.0293
Loa Loa (eye worm)	hypothetical protein	0.0154	0.0725	0.0719
Schistosoma mansoni	serine/threonine protein kinase	0.0607	0.2983	0.2983
Onchocerca volvulus		0.0033	0.0118	0.092
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Onchocerca volvulus		0.0044	0.0174	0.1379
Onchocerca volvulus		0.0044	0.0174	0.1379
Brugia malayi	Plekhf2 protein	0.0044	0.0174	0.0563
Echinococcus multilocularis	rac serine:threonine kinase	0.005	0.0203	0.0203
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0066	0.0286	0.0286
Brugia malayi	regulator of G-protein signaling egl-10	0.0244	0.1172	0.3916
Schistosoma mansoni	z-protein (S1r protein)	0.0244	0.1172	0.1172
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0044	0.0174	0.0174
Onchocerca volvulus		0.0036	0.0135	0.106
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0135	0.4386
Schistosoma mansoni	serine/threonine protein kinase	0.2013	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Loa Loa (eye worm)	Plekhf2 protein	0.0044	0.0174	0.0168
Entamoeba histolytica	PH domain containing protein kinase, putative	0.005	0.0203	0.0293
Trypanosoma cruzi	PH domain containing protein, putative	0.0044	0.0174	0.7586
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0033	0.0118	0.0118
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0044	0.0174	0.7586
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0044	0.0174	0.0174
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.005	0.0203	1
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0044	0.0174	0.0168
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0007	0.0007
Brugia malayi	Pre-SET motif family protein	0.0033	0.0118	0.0375
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0011	0.0009	0.0009
Schistosoma mansoni	serine/threonine-protein kinase	0.005	0.0203	0.0203
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.005	0.0203	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0184	0.0184
Brugia malayi	hypothetical protein	0.0016	0.0038	0.0104
Schistosoma mansoni	goodpasture antigen-binding protein	0.0044	0.0174	0.0174
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0569	0.0563
Onchocerca volvulus		0.0044	0.0174	0.1379
Schistosoma mansoni	regulator of G protein signaling	0.0244	0.1172	0.1172
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0007	0.0007
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0007	0.0007
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0044	0.0174	0.0174
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0017	0.004	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0135	0.0129
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0007	0.0007
Echinococcus multilocularis	oxysterol binding protein 3	0.0044	0.0174	0.0174
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0033	0.0118	0.0118
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0053	0.0222	0.0215
Schistosoma mansoni	oxysterol-binding protein 1	0.0044	0.0174	0.0174
Echinococcus granulosus	cpg binding protein	0.0032	0.0118	0.0118
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0044	0.0174	0.0168
Echinococcus granulosus	calcium dependent secretion activator 1	0.0044	0.0174	0.0174
Brugia malayi	Variant SH3 domain containing protein	0.0044	0.0174	0.0563
Echinococcus granulosus	Pleckstrin y	0.0044	0.0174	0.0174
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Echinococcus multilocularis	GPCR, family 2	0.0017	0.004	0.004
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0007	0.0007
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0044	0.0174	0.7586
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Schistosoma mansoni	rho gtpase activating protein	0.0044	0.0174	0.0174
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0044	0.0174	0.7586
Brugia malayi	Protein kinase domain containing protein	0.005	0.0203	0.0661
Schistosoma mansoni	hypothetical protein	0.0017	0.004	0.004
Echinococcus granulosus	GRB2 associated binding protein 3	0.0044	0.0174	0.0174
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0044	0.0174	0.7586
Loa Loa (eye worm)	PH domain-containing protein	0.0044	0.0174	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.005	0.0203	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0044	0.0174	0.0357
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0363	0.1767	0.1762
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Trypanosoma cruzi	NIMA-related kinase, putative	0.005	0.0203	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0184	0.0184
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.005	0.0203	1
Echinococcus granulosus	oxysterol binding protein 9	0.0044	0.0174	0.0174
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0044	0.0174	0.0174
Trichomonas vaginalis	hypothetical protein	0.0044	0.0174	0.0357
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.005	0.0203	1
Leishmania major	hypothetical protein, conserved	0.0044	0.0174	0.7586
Schistosoma mansoni	oxysterol-binding protein 1	0.0044	0.0174	0.0174
Mycobacterium ulcerans	lipase LipD	0.0036	0.0135	0.5
Schistosoma mansoni	microtubule-associated protein tau	0.067	0.3301	0.3301
Echinococcus granulosus	microtubule associated protein 2	0.067	0.3301	0.3301
Brugia malayi	hypothetical protein	0.0044	0.0174	0.0563
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trichomonas vaginalis	conserved hypothetical protein	0.0244	0.1172	0.9555
Echinococcus granulosus	pdz domain containing protein	0.0044	0.0174	0.0174
Entamoeba histolytica	PH domain containing protein kinase, putative	0.005	0.0203	0.0293
Toxoplasma gondii	Oxysterol-binding protein	0.0044	0.0174	0.5424
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus granulosus	Pleckstrin y	0.0044	0.0174	0.0174
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.1769	0.8784	0.8784
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus granulosus	oxysterol binding protein 1	0.0044	0.0174	0.0174
Trichomonas vaginalis	conserved hypothetical protein	0.0244	0.1172	0.9555
Brugia malayi	Oxysterol binding protein	0.0044	0.0174	0.0563
Mycobacterium ulcerans	esterase/lipase LipP	0.0036	0.0135	0.5
Toxoplasma gondii	hypothetical protein	0.0044	0.0174	0.5424
Entamoeba histolytica	hypothetical protein	0.0244	0.1172	1
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Mycobacterium ulcerans	hypothetical protein	0.0036	0.0135	0.5
Echinococcus granulosus	Regulator of G protein signaling 20	0.0244	0.1172	0.1172
Schistosoma mansoni	cpg binding protein	0.0032	0.0118	0.0118
Trichomonas vaginalis	centaurin/arf, putative	0.0044	0.0174	0.0357
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0044	0.0174	0.000000066692
Brugia malayi	probable spectrin beta chain	0.0044	0.0174	0.0563
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0007	0.0007
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0044	0.0174	0.0357
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Echinococcus multilocularis	Pleckstrin y	0.0044	0.0174	0.0174
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0244	0.1172	0.1167
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Schistosoma mansoni	retinoic acid receptor RXR	0.001	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0135	0.0129
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Leishmania major	hypothetical protein, conserved	0.0044	0.0174	0.7586
Trypanosoma cruzi	PH domain containing protein, putative	0.0044	0.0174	0.7586
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Trypanosoma brucei	protein kinase, putative	0.005	0.0203	1
Leishmania major	folate/biopterin transporter, putative	0.005	0.0203	1
Trichomonas vaginalis	set domain proteins, putative	0.0253	0.1221	1
Loa Loa (eye worm)	uncoordinated protein 104	0.0044	0.0174	0.0168
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0031	0.0109	0.0109
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.005	0.0203	1
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.005	0.0203	1
Echinococcus multilocularis	Oxysterol binding protein 11	0.0044	0.0174	0.0174
Schistosoma mansoni	hypothetical protein	0.0017	0.004	0.004
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0044	0.0174	0.0174
Onchocerca volvulus		0.0044	0.0174	0.1379
Brugia malayi	hypothetical protein	0.0244	0.1172	0.3916
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.001	0.0007	0.0007
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.005	0.0203	1
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0044	0.0174	0.0174
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0011	0.0009	0.0009
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Brugia malayi	Oxysterol-binding protein	0.0044	0.0174	0.0563
Brugia malayi	F/Y-rich N-terminus family protein	0.0011	0.0009	0.0007
Entamoeba histolytica	hypothetical protein	0.005	0.0203	0.0293
Trypanosoma brucei	PH domain containing protein, putative	0.0044	0.0174	0.7586
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0044	0.0174	0.0174
Echinococcus granulosus	ecdysone induced protein 78C	0.001	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Schistosoma mansoni	serine/threonine protein kinase	0.2013	1	1
Echinococcus granulosus	beta 1 syntrophin	0.0044	0.0174	0.0174
Echinococcus granulosus	Pleckstrin y	0.0044	0.0174	0.0174
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.2013	1	1
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0138	0.0131
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.005	0.0203	1
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0044	0.0174	0.0357
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0011	0.0013	0.0013
Schistosoma mansoni	vav2	0.0044	0.0174	0.0174
Brugia malayi	regulator of G-protein signaling rgs-7	0.0244	0.1172	0.3916
Trichomonas vaginalis	protein transport protein sec7, putative	0.0044	0.0174	0.0357
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.0363	0.1767	0.1767
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.001	0.0007	0.0007
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trichomonas vaginalis	conserved hypothetical protein	0.0244	0.1172	0.9555
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0044	0.0174	0.0174
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0184	0.0177
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0244	0.1172	0.1172
Loa Loa (eye worm)	RGS-3 protein	0.0244	0.1172	0.1167
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0053	0.0222	0.0722
Loa Loa (eye worm)	hypothetical protein	0.0244	0.1172	0.1167
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Brugia malayi	Latrophilin receptor protein 2	0.0017	0.004	0.0112
Schistosoma mansoni	growth factor receptor-bound protein	0.0044	0.0174	0.0174
Loa Loa (eye worm)	PXA domain-containing protein	0.0244	0.1172	0.1167
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.001	0.0007	0.0007
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0044	0.0174	0.0174
Echinococcus granulosus	dynamin 1	0.0044	0.0174	0.0174
Plasmodium falciparum	oxysterol-binding protein, putative	0.0044	0.0174	0.7586
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Onchocerca volvulus	Putative zinc finger protein	0.0044	0.0174	0.1379
Brugia malayi	beta-lactamase	0.0036	0.0135	0.0432
Trichomonas vaginalis	kinesin light chain, putative	0.0044	0.0174	0.0357
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Onchocerca volvulus		0.0044	0.0174	0.1379
Brugia malayi	Cytohesin 3	0.0044	0.0174	0.0563
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.001	0.0007	0.0007
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0033	0.0118	0.0118
Loa Loa (eye worm)	AGC/AKT protein kinase	0.005	0.0203	0.0197
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0017	0.004	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0244	0.1172	0.9555
Schistosoma mansoni	hypothetical protein	0.0437	0.2134	0.2134
Onchocerca volvulus	Huntingtin homolog	0.0123	0.0569	0.463
Trypanosoma brucei	rac serine-threonine kinase, putative	0.005	0.0203	1
Onchocerca volvulus		0.0044	0.0174	0.1379
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0044	0.0174	0.0357
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Entamoeba histolytica	PH domain containing protein kinase, putative	0.005	0.0203	0.0293
Brugia malayi	MAX-1A	0.0044	0.0174	0.0563
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0044	0.0174	0.0174
Echinococcus multilocularis	beta adrenergic receptor kinase	0.2013	1	1
Schistosoma mansoni	goodpasture antigen-binding protein	0.0044	0.0174	0.0174
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0044	0.0174	0.0174
Echinococcus granulosus	DCC interacting protein 13 beta	0.0044	0.0174	0.0174
Schistosoma mansoni	coup transcription factor	0.001	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0017	0.004	0.004
Echinococcus multilocularis	pdz domain containing protein	0.0044	0.0174	0.0174
Loa Loa (eye worm)	syntrophin-1	0.0044	0.0174	0.0168
Echinococcus multilocularis	oxysterol binding protein 9	0.0044	0.0174	0.0174
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0044	0.0174	0.0174
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0244	0.1172	0.1172
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus multilocularis	regulator of G protein signaling 3	0.0244	0.1172	0.1172
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0036	0.0135	0.0432
Leishmania major	hypothetical protein, conserved	0.0036	0.0135	0.4386
Echinococcus granulosus	serine/threonine protein kinase	0.005	0.0203	0.0203
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0044	0.0174	0.0174
Loa Loa (eye worm)	hypothetical protein	0.0244	0.1172	0.1167
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Echinococcus multilocularis	dnaJ subfamily B	0.0437	0.2134	0.2134
Schistosoma mansoni	zinc finger protein	0.0044	0.0174	0.0174
Leishmania major	serine/threonine-protein kinase a, putative	0.005	0.0203	1
Schistosoma mansoni	RAR-like nuclear receptor	0.001	0.0007	0.0007
Onchocerca volvulus		0.0036	0.0135	0.106
Trypanosoma brucei	hypothetical protein, conserved	0.0036	0.0135	0.4386
Brugia malayi	TBC domain containing protein	0.0044	0.0174	0.0563
Schistosoma mansoni	hypothetical protein	0.0011	0.0013	0.0013
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0184	0.0184
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Loa Loa (eye worm)	beta-lactamase	0.0036	0.0135	0.0129
Echinococcus multilocularis	muscleblind protein 1	0.0154	0.0725	0.0725
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Schistosoma mansoni	syntrophin	0.0044	0.0174	0.0174
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0044	0.0174	0.0174
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Schistosoma mansoni	hypothetical protein	0.0036	0.0138	0.0138
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0044	0.0174	0.5424
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0044	0.0174	0.0174
Brugia malayi	Dynamin	0.0044	0.0174	0.0563
Brugia malayi	PH domain containing protein	0.0044	0.0174	0.0563
Schistosoma mansoni	regulator of G protein signaling	0.0244	0.1172	0.1172
Trichomonas vaginalis	protein transport protein sec7, putative	0.0044	0.0174	0.0357
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0044	0.0174	0.7586
Brugia malayi	PXA domain containing protein	0.0244	0.1172	0.3916
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.0363	0.1767	0.1767
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0033	0.0118	0.0118
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0044	0.0174	0.0174
Onchocerca volvulus		0.0044	0.0174	0.1379
Entamoeba histolytica	hypothetical protein	0.0244	0.1172	1
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0184	0.0595
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Plasmodium vivax	PH domain containing protein	0.0044	0.0174	0.7586
Echinococcus granulosus	G protein coupled receptor kinase 1	0.1769	0.8784	0.8784
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0044	0.0174	0.0174
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0135	0.0135
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0244	0.1172	0.1172
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0033	0.0118	0.0118
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Brugia malayi	Cadps2 protein	0.0044	0.0174	0.0563
Echinococcus granulosus	dnaJ subfamily B	0.0437	0.2134	0.2134
Echinococcus multilocularis	regulator of G protein signaling	0.0244	0.1172	0.1172
Onchocerca volvulus	outspread protein homolog	0.0044	0.0174	0.1379
Schistosoma mansoni	hypothetical protein	0.0017	0.004	0.004
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.005	0.0203	0.715
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0135	0.0129
Leishmania major	protein kinase, putative	0.005	0.0203	1
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0036	0.0135	0.0129
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0044	0.0174	0.0174
Echinococcus multilocularis	muscleblind protein	0.0154	0.0725	0.0725
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0044	0.0174	0.0174
Toxoplasma gondii	AtPH1 family protein	0.0044	0.0174	0.5424
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.001	0.0007	0.0007
Echinococcus granulosus	muscleblind protein	0.0154	0.0725	0.0725
Echinococcus multilocularis	expressed protein	0.0244	0.1172	0.1172
Schistosoma mansoni	cpg binding protein	0.0032	0.0118	0.0118
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0184	0.0184
Brugia malayi	Variant SH3 domain containing protein	0.0044	0.0174	0.0563
Trypanosoma cruzi	Protein kinase B	0.005	0.0203	1
Loa Loa (eye worm)	cytohesin 3	0.0044	0.0174	0.0168
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Mycobacterium ulcerans	beta-lactamase	0.0036	0.0135	0.5
Trichomonas vaginalis	alpha chimerin, putative	0.0044	0.0174	0.0357
Trichomonas vaginalis	conserved hypothetical protein	0.0244	0.1172	0.9555
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0044	0.0174	0.0563
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0244	0.1172	0.3916
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0044	0.0174	0.7586
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0017	0.004	0.004
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0044	0.0174	0.7586
Echinococcus granulosus	histone lysine methyltransferase setb	0.0033	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0244	0.1172	0.1172
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0244	0.1172	0.3916
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0244	0.1172	0.1172
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0135	0.0129
Brugia malayi	Muscleblind-like protein	0.0154	0.0725	0.2412
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Brugia malayi	hypothetical protein	0.0025	0.0082	0.0254
Loa Loa (eye worm)	histone methyltransferase	0.0011	0.0009	0.0003
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0044	0.0174	0.0174
Echinococcus multilocularis	beta 1 syntrophin	0.0044	0.0174	0.0174
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.001	0.0007	0.0007
Trichomonas vaginalis	centaurin gamma, putative	0.0044	0.0174	0.0357
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.005	0.0203	0.0627
Schistosoma mansoni	regulator of G protein signaling	0.0244	0.1172	0.1172
Loa Loa (eye worm)	rho-GTPase-activating	0.0044	0.0174	0.0168
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.001	0.0007	0.0007
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0607	0.2983	0.2979
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Trichomonas vaginalis	centaurin beta, putative	0.0044	0.0174	0.0357
Echinococcus granulosus	regulator of G protein signaling 7	0.0244	0.1172	0.1172
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0044	0.0174	0.0168
Echinococcus multilocularis	myotubularin protein 13	0.0044	0.0174	0.0174
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0053	0.0222	0.0722
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.005	0.0203	0.0627
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.005	0.0203	1
Schistosoma mansoni	nuclear hormone receptor	0.001	0.0007	0.0007
Echinococcus granulosus	regulator of G protein signaling 3	0.0244	0.1172	0.1172
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Echinococcus multilocularis	Pleckstrin y	0.0044	0.0174	0.0174
Onchocerca volvulus		0.0253	0.1221	1
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.001	0.0007	0.0007
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0082	0.0076
Plasmodium vivax	SET domain protein, putative	0.0033	0.0118	0.299
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0033	0.0118	0.0118
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Schistosoma mansoni	axis inhibition protein axin	0.0244	0.1172	0.1172
Echinococcus granulosus	Rho GTPase activating protein 24	0.0044	0.0174	0.0174
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Schistosoma mansoni	hypothetical protein	0.0044	0.0174	0.0174
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0059	0.0252	1
Toxoplasma gondii	protein kinase domain-containing protein	0.005	0.0203	0.715
Brugia malayi	A-kinase anchor protein 10, precursor	0.0244	0.1172	0.3916
Echinococcus multilocularis	axis inhibition protein axin	0.0244	0.1172	0.1172
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.0363	0.1767	0.1762
Brugia malayi	beta-lactamase family protein	0.0036	0.0135	0.0432
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0184	0.0184
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Entamoeba histolytica	PH domain containing protein kinase, putative	0.005	0.0203	0.0293
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0044	0.0174	0.0174
Loa Loa (eye worm)	hypothetical protein	0.0244	0.1172	0.1167
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0044	0.0174	0.0563
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0033	0.0118	0.2138
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.001	0.0007	0.0007
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0044	0.0174	0.7586
Trypanosoma cruzi	PH domain containing protein, putative	0.0044	0.0174	0.7586
Brugia malayi	Dynamin	0.0044	0.0174	0.0563
Echinococcus multilocularis	regulator of G protein signaling 7	0.0244	0.1172	0.1172
Echinococcus granulosus	Oxysterol binding protein 11	0.0044	0.0174	0.0174
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0223	0.1068	0.1062
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0044	0.0174	0.0563
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.0607	0.2983	1
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0569	0.0563
Echinococcus granulosus	axis inhibition protein axin	0.0244	0.1172	0.1172
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.001	0.0007	0.0007
Entamoeba histolytica	protein kinase, putative	0.005	0.0203	0.0293
Brugia malayi	Pre-SET motif family protein	0.0223	0.1068	0.3564
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0135	0.4386
Schistosoma mansoni	regulator of G protein signaling	0.0244	0.1172	0.1172
Echinococcus multilocularis	oxysterol binding protein 1	0.0044	0.0174	0.0174
Brugia malayi	hypothetical protein	0.0123	0.0569	0.1888
Brugia malayi	PXA domain containing protein	0.0244	0.1172	0.3916
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.005	0.0203	1
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.001	0.0007	0.0007
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0135	0.0135
Echinococcus multilocularis	microtubule associated protein 2	0.067	0.3301	0.3301
Echinococcus granulosus	beta LACTamase domain containing family member	0.0036	0.0135	0.0135
Echinococcus multilocularis	regulator of G protein signaling 7	0.0244	0.1172	0.1172
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.0363	0.1767	0.5914
Echinococcus multilocularis	FTZ F1 alpha	0.001	0.0007	0.0007
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trichomonas vaginalis	conserved hypothetical protein	0.0244	0.1172	0.9555
Schistosoma mansoni	hypothetical protein	0.0044	0.0174	0.0174
Echinococcus multilocularis	thyroid hormone receptor alpha	0.001	0.0007	0.0007
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.005	0.0203	1
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0044	0.0174	0.0174
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.005	0.0203	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0011	0.0013	0.0013
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Mycobacterium leprae	conserved hypothetical protein	0.0036	0.0135	0.5
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0044	0.0174	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0118	0.0112
Schistosoma mansoni	steroid hormone receptor ad4bp	0.001	0.0007	0.0007
Trichomonas vaginalis	centaurin/arf, putative	0.0044	0.0174	0.0357
Echinococcus multilocularis	regulator of G protein signaling 3	0.0244	0.1172	0.1172
Loa Loa (eye worm)	hypothetical protein	0.0154	0.0725	0.0719
Echinococcus granulosus	GPCR family 2	0.0017	0.004	0.004
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.005	0.0203	1
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0044	0.0174	0.7586
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0044	0.0174	0.0357
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0229	0.1101	1
Echinococcus granulosus	expressed protein	0.0244	0.1172	0.1172
Plasmodium vivax	hypothetical protein, conserved	0.0036	0.0135	0.4386
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Trypanosoma cruzi	hypothetical protein	0.0044	0.0174	0.7586
Loa Loa (eye worm)	hypothetical protein	0.0017	0.004	0.0033
Brugia malayi	beta-lactamase family protein	0.0036	0.0135	0.0432
Onchocerca volvulus	Huntingtin homolog	0.0123	0.0569	0.463
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0244	0.1172	0.1172
Echinococcus granulosus	regulator of G protein signaling 7	0.0244	0.1172	0.1172
Plasmodium falciparum	PH domain-containing protein, putative	0.0044	0.0174	0.7586
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0044	0.0174	0.0357
Loa Loa (eye worm)	hypothetical protein	0.0244	0.1172	0.1167
Trichomonas vaginalis	AGC family protein kinase	0.005	0.0203	0.0627
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Toxoplasma gondii	ABC1 family protein	0.0036	0.0135	0.3136
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0044	0.0174	0.0174
Brugia malayi	Uncoordinated protein 104	0.0044	0.0174	0.0563
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0044	0.0174	0.0174
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0222	0.0215
Trichomonas vaginalis	centaurin alpha, putative	0.0044	0.0174	0.0357
Loa Loa (eye worm)	hypothetical protein	0.0244	0.1172	0.1167
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0174	0.0357
Echinococcus multilocularis	dynamin 1	0.0044	0.0174	0.0174
Onchocerca volvulus		0.0031	0.0109	0.0843
Echinococcus multilocularis	cytohesin 1	0.0044	0.0174	0.0174
Leishmania major	protein kinase, putative	0.005	0.0203	1
Entamoeba histolytica	hypothetical protein	0.0244	0.1172	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0184	0.0184
Echinococcus multilocularis	ecdysone induced protein 78C	0.001	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Brugia malayi	Pleckstrin Homology Domain	0.0044	0.0174	0.0563
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0174	0.0168
Echinococcus multilocularis	axis inhibition protein axin	0.0244	0.1172	0.1172
Entamoeba histolytica	PH domain containing protein kinase, putative	0.005	0.0203	0.0293
Schistosoma mansoni	hypothetical protein	0.0017	0.004	0.004
Loa Loa (eye worm)	hypothetical protein	0.0244	0.1172	0.1167
Echinococcus granulosus	regulator of G protein signaling 3	0.0244	0.1172	0.1172
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.001	0.0007	0.0007
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.001	0.0007	0.0007
Schistosoma mansoni	hypothetical protein	0.0044	0.0174	0.0174
Trypanosoma cruzi	NIMA-related kinase, putative	0.005	0.0203	1
Echinococcus granulosus	oxysterol binding protein 3	0.0044	0.0174	0.0174
Brugia malayi	CXXC zinc finger family protein	0.0031	0.0109	0.0344

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2299091

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1789927