Detailed information for compound 1791879

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 627.119 | Formula: C30H27ClN10O2S
  • H donors: 3 H acceptors: 6 LogP: 6.53 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: Clc1ccc2c(c1)nccc2NC(=S)N1CCN(CC1)c1nc(Nc2ccc(cc2)[N+](=O)[O-])nc(n1)Nc1ccccc1C
  • InChi: 1S/C30H27ClN10O2S/c1-19-4-2-3-5-24(19)34-28-36-27(33-21-7-9-22(10-8-21)41(42)43)37-29(38-28)39-14-16-40(17-15-39)30(44)35-25-12-13-32-26-18-20(31)6-11-23(25)26/h2-13,18H,14-17H2,1H3,(H,32,35,44)(H2,33,34,36,37,38)
  • InChiKey: VCFYSSGJIBRSOQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Echinococcus granulosus Rac GTPase activating protein 1 0.0321 0.0483 0.0482
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.005 0.0058 0.0817
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0321 0.0483 0.0482
Schistosoma mansoni smad1 5 8 and 0.0019 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0058 0.0835
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Schistosoma mansoni hypothetical protein 0.0089 0.0119 0.0118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0007 0.0094
Toxoplasma gondii pyruvate kinase PyKII 0.0106 0.0146 0.1198
Loa Loa (eye worm) pyruvate kinase 0.0206 0.0304 0.0303
Schistosoma mansoni hypothetical protein 0.0229 0.034 0.0338
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0206 0.0304 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0011 0.0009
Echinococcus multilocularis serine:threonine protein kinase N2 0.0454 0.0692 0.0691
Echinococcus multilocularis partitioning defective protein 6 0.0321 0.0484 0.0483
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0044 0.0639
Brugia malayi intermediate filament protein 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0009
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.005 0.0058 0.0817
Echinococcus granulosus allatostatin A receptor 0.0019 0.0009 0.0008
Trichomonas vaginalis pyruvate kinase, putative 0.0206 0.0304 0.4391
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0009 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0017 0.0252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0112 0.0155 0.0154
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0009 0.0008
Echinococcus granulosus o acyltransferase membrane bound domain 0.005 0.0058 0.0056
Loa Loa (eye worm) pyruvate kinase 0.0043 0.0048 0.0047
Schistosoma mansoni hypothetical protein 0.0087 0.0116 0.0115
Brugia malayi MH2 domain containing protein 0.0019 0.0009 0.0009
Echinococcus multilocularis Diacylglycerol kinase theta 0.0321 0.0483 0.0482
Brugia malayi Protein kinase domain containing protein 0.0331 0.0499 0.0499
Brugia malayi MBOAT family protein 0.005 0.0058 0.0058
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0055 0.0054
Brugia malayi MH2 domain containing protein 0.0274 0.041 0.0409
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0039 0.0037
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0095 0.0094
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0003 0.0002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0177 0.0258 0.0256
Schistosoma mansoni rac gtpase activating protein 0.0321 0.0483 0.0482
Brugia malayi G-protein coupled receptor 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0206 0.0304 0.0303
Echinococcus multilocularis gamma secretase subunit aph 1 0.0196 0.0287 0.0286
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.005 0.0058 0.0056
Echinococcus granulosus N chimaerin 0.0321 0.0483 0.0482
Echinococcus granulosus Smad4 0.0019 0.0009 0.0008
Toxoplasma gondii diacylglycerol kinase, putative 0.0321 0.0483 0.4185
Brugia malayi Protein kinase domain containing protein 0.0454 0.0692 0.0692
Echinococcus multilocularis peregrin 0.0028 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Plasmodium falciparum pyruvate kinase 0.0206 0.0304 0.6789
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0011 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0086 0.1244
Brugia malayi Hhat protein 0.005 0.0058 0.0058
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0017 0.0016
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0011 0.0091
Echinococcus multilocularis survival motor neuron protein 1 0.047 0.0717 0.0716
Loa Loa (eye worm) hypothetical protein 0.0454 0.0692 0.0691
Echinococcus granulosus pyruvate kinase 0.0106 0.0146 0.0145
Echinococcus multilocularis protein dispatched 1 0.0047 0.0053 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Echinococcus granulosus myotubularin protein 13 0.0321 0.0483 0.0482
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0056
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0331 0.0499 0.0498
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0017 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0171 0.0169
Toxoplasma gondii diacylglycerol acyltransferase 0.0164 0.0237 0.2001
Brugia malayi Protein kinase domain containing protein 0.0454 0.0692 0.0692
Schistosoma mansoni pyruvate kinase 0.0206 0.0304 0.0303
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.0179 0.0179
Trichomonas vaginalis beta-galactosidase, putative 0.0247 0.0367 0.5307
Loa Loa (eye worm) hypothetical protein 0.638 1 1
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0739 0.114 0.1139
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0454 0.0692 0.0691
Echinococcus multilocularis serotonin receptor 0.0019 0.0009 0.0008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0009 0.0008
Onchocerca volvulus 0.0057 0.0069 0.0529
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0039 0.0569
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.005 0.0058 0.0817
Leishmania major pyruvate kinase 0.0206 0.0304 0.2657
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0122 0.0172 0.017
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.002
Echinococcus multilocularis chromobox protein 1 0.0068 0.0086 0.0085
Entamoeba histolytica vacuolar protein sorting 26 0.005 0.0058 0.0817
Brugia malayi manba-prov protein 0.008 0.0105 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Brugia malayi MH1 domain containing protein 0.0019 0.0009 0.0009
Treponema pallidum alginate O-acetylation protein (algI) 0.005 0.0058 0.5
Loa Loa (eye worm) hypothetical protein 0.0063 0.0078 0.0077
Echinococcus granulosus o acyltransferase membrane bound domain 0.005 0.0058 0.0056
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0019
Entamoeba histolytica protein kinase, putative 0.0454 0.0692 1
Schistosoma mansoni microtubule-associated protein tau 0.0956 0.1482 0.148
Brugia malayi CXXC zinc finger family protein 0.0057 0.0069 0.0069
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis protein kinase c iota type 0.5149 0.8067 0.8067
Onchocerca volvulus 0.0035 0.0035 0.0226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0112 0.0155 0.0154
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0033 0.0032
Trypanosoma brucei pyruvate kinase 1 0.0206 0.0304 0.2657
Echinococcus granulosus sex peptide receptor 0.0019 0.0009 0.0008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0039 0.0037
Brugia malayi RE15519p 0.0019 0.0009 0.0009
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0017 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0016 0.0128
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0048 0.0056 0.0055
Echinococcus multilocularis lysosomal alpha glucosidase 0.0148 0.0213 0.0211
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0008
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0009 0.0008
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0016 0.0211
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0454 0.0692 0.0691
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.005 0.0058 0.0056
Onchocerca volvulus 0.003 0.0026 0.0151
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0009 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0016 0.0016
Brugia malayi ecdysteroid receptor 0.0024 0.0017 0.0017
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0089 0.0119 0.0118
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.0692 0.0691
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0296 0.0444 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0009 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0179 0.0178
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.005 0.0058 0.0056
Schistosoma mansoni protein kinase C mu 0.0331 0.0499 0.0498
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.0739 0.114 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0016 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Mycobacterium leprae Probable pyruvate kinase PykA 0.0206 0.0304 1
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0321 0.0483 0.0482
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0031 0.0454
Brugia malayi MBOAT family protein 0.005 0.0058 0.0058
Entamoeba histolytica protein kinase, putative 0.0454 0.0692 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.005 0.0058 0.0056
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0019 0.0009 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0016 0.0211
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.005 0.0058 0.0056
Brugia malayi MH1 domain containing protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Schistosoma mansoni gamma-secretase subunit aph-1 0.0196 0.0287 0.0286
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0009 0.0008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0089 0.0119 0.0119
Entamoeba histolytica protein kinase, putative 0.0454 0.0692 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0009 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0018 0.0016
Schistosoma mansoni biogenic amine receptor 0.0019 0.0009 0.0008
Brugia malayi MBOAT family protein 0.005 0.0058 0.0058
Entamoeba histolytica hypothetical protein 0.0321 0.0483 0.6979
Entamoeba histolytica beta-galactosidase, putative 0.0167 0.0242 0.3478
Brugia malayi Dopamine receptor protein 2 0.0019 0.0009 0.0009
Schistosoma mansoni serine/threonine kinase 0.0454 0.0692 0.0691
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus raf serine:threonine protein kinase 0.0321 0.0483 0.0482
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0042 0.004
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.005 0.0058 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni chromobox protein 0.0068 0.0086 0.0085
Loa Loa (eye worm) Smad1 0.0019 0.0009 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0031 0.0454
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0321 0.0484 0.0483
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.013 0.0129
Schistosoma mansoni lamin 0.0026 0.0021 0.002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.161 0.2508 0.2507
Brugia malayi jmjC domain containing protein 0.0037 0.0039 0.0038
Echinococcus granulosus neuropeptide receptor 0.0019 0.0009 0.0008
Brugia malayi Bromodomain containing protein 0.0028 0.0024 0.0024
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0096 0.013 0.0129
Brugia malayi Pyruvate kinase, M2 isozyme 0.0206 0.0304 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0017 0.0016
Trichomonas vaginalis beta-mannosidase, putative 0.008 0.0105 0.1523
Echinococcus multilocularis N chimaerin 0.0321 0.0483 0.0482
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.013 0.013
Echinococcus multilocularis serotonin receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0017 0.0016
Echinococcus granulosus lysophospholipid acyltransferase 7 0.005 0.0058 0.0056
Echinococcus granulosus protein TFG 0.0321 0.0484 0.0483
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0031 0.0029
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0044 0.0043
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0112 0.0155 0.0154
Schistosoma mansoni cpg binding protein 0.006 0.0074 0.0073
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0017 0.0016
Brugia malayi TAR-binding protein 0.0127 0.0179 0.0179
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0024 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0016 0.0016
Echinococcus multilocularis cpg binding protein 0.006 0.0074 0.0073
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0009 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0031 0.0454
Echinococcus multilocularis raf serine:threonine protein kinase 0.0321 0.0483 0.0482
Echinococcus granulosus pyruvate kinase 0.0106 0.0146 0.0145
Entamoeba histolytica hypothetical protein 0.0177 0.0258 0.3708
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0075 0.0567
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0009 0.0008
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0017 0.0016
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0017 0.0252
Schistosoma mansoni cpg binding protein 0.0057 0.0069 0.0068
Brugia malayi C1-like domain containing protein 0.0331 0.0499 0.0499
Brugia malayi Calcitonin receptor-like protein seb-1 0.028 0.042 0.0419
Schistosoma mansoni Smad4 0.0019 0.0009 0.0008
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0739 0.114 1
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) raf kinase 0.0321 0.0483 0.0482
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.0023 0.0022
Echinococcus multilocularis lysosomal alpha glucosidase 0.0148 0.0213 0.0211
Leishmania major alpha glucosidase II subunit, putative 0.0033 0.0031 0.0264
Brugia malayi hypothetical protein 0.0122 0.0172 0.0171
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0011 0.0083
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0017 0.0016
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0017 0.0017
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) AGC/PKN protein kinase 0.0454 0.0692 0.0691
Brugia malayi Pre-SET motif family protein 0.0141 0.0201 0.0201
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0095 0.0094
Onchocerca volvulus Huntingtin homolog 0.0122 0.0172 0.1435
Echinococcus granulosus sterol O acyltransferase 1 0.005 0.0058 0.0056
Onchocerca volvulus Pyruvate kinase homolog 0.0206 0.0304 0.2605
Trichomonas vaginalis porcupine, putative 0.005 0.0058 0.0835
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0321 0.0483 0.0482
Schistosoma mansoni hypothetical protein 0.0542 0.083 0.0829
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0499 0.0498
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0025
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0009 0.0008
Brugia malayi RhoGAP domain containing protein 0.0321 0.0483 0.0483
Plasmodium vivax pyruvate kinase, putative 0.0206 0.0304 0.6789
Brugia malayi G protein-coupled receptor 0.0019 0.0009 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0177 0.0258 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0063 0.0906
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0024 0.0023
Trichomonas vaginalis transmembrane protein nessy, putative 0.005 0.0058 0.0835
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0112 0.0155 0.0154
Echinococcus multilocularis pyruvate kinase 0.0206 0.0304 0.0303
Loa Loa (eye worm) hypothetical protein 0.028 0.042 0.0418
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0009 0.0009
Trypanosoma brucei glycerol uptake protein, putative 0.005 0.0058 0.0496
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0009 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus GPCR family 2 0.0089 0.0119 0.0118
Schistosoma mansoni smad1 5 8 and 0.0019 0.0009 0.0008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Loa Loa (eye worm) hypothetical protein 0.047 0.0717 0.0716
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0009 0.0009
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0454 0.0692 0.0691
Brugia malayi Beta-glucuronidase precursor 0.0229 0.0339 0.0339
Brugia malayi neuropeptide F receptor 0.0019 0.0009 0.0009
Onchocerca volvulus Pyruvate kinase homolog 0.0206 0.0304 0.2605
Brugia malayi Latrophilin receptor protein 2 0.0089 0.0119 0.0119
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) pyruvate kinase 0.0206 0.0304 0.0303
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0008
Trypanosoma cruzi PB1 domain containing protein, putative 0.0321 0.0484 0.4239
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0009 0.0008
Trypanosoma brucei RNA helicase, putative 0.0229 0.034 0.2969
Echinococcus granulosus survival motor neuron protein 1 0.047 0.0717 0.0716
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.005 0.0058 0.0056
Onchocerca volvulus 0.0321 0.0483 0.4192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0009 0.0008
Plasmodium falciparum pyruvate kinase 2 0.0106 0.0146 0.3184
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0321 0.0483 0.0482
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0017 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Brugia malayi protein kinase C II. 0.0774 0.1196 0.1196
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0009 0.0008
Loa Loa (eye worm) PAR-6 protein 0.0321 0.0484 0.0483
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Giardia lamblia PHD finger protein 15 0.0028 0.0024 0.0753
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.013
Loa Loa (eye worm) MBOAT family protein 0.005 0.0058 0.0056
Trypanosoma cruzi PB1 domain containing protein, putative 0.0321 0.0484 0.4239
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) TAR-binding protein 0.0127 0.0179 0.0178
Schistosoma mansoni pyruvate kinase 0.0206 0.0304 0.0303
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.005 0.0059 0.0057
Brugia malayi larval opioid receptor 0.0019 0.0009 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0017 0.0252
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0075 0.0645
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0095 0.0094
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0011 0.0156
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.638 1 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0007 0.0179
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0089 0.0119 0.0118
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0177 0.0258 0.0256
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.0035 0.0034
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0009 0.0008
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0009 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0042 0.0046 0.0388
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0017 0.0016
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0739 0.114 1
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Trichomonas vaginalis maltase-glucoamylase, putative 0.0033 0.0031 0.0454
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.005 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Schistosoma mansoni protein kinase C mu 0.0321 0.0483 0.0482
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.005 0.0058 0.0056
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0296 0.0444 0.0443
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Loa Loa (eye worm) pyruvate kinase 0.0206 0.0304 0.0303
Trypanosoma brucei Aph-1 protein, putative 0.0076 0.01 0.0862
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0017 0.0252
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0009 0.0009
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0011 0.0083
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0011 0.0091
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0007 0.0179
Schistosoma mansoni alpha glucosidase 0.0033 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0041
Toxoplasma gondii hypothetical protein 0.0034 0.0033 0.0195
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0009 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0044 0.0634
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0041
Brugia malayi Glycosyl hydrolases family 31 protein 0.0148 0.0213 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0009 0.0008
Brugia malayi steroid hormone receptor 0.0024 0.0017 0.0017
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni intermediate filament proteins 0.0026 0.0021 0.002
Echinococcus granulosus NDR protein kinase 0.0454 0.0692 0.0691
Schistosoma mansoni gabp alpha 0.0073 0.0095 0.0094
Echinococcus multilocularis serine:threonine protein kinase N2 0.0454 0.0692 0.0691
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0454 0.0692 0.0691
Echinococcus granulosus somatostatin receptor 0.0019 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0017 0.0017
Schistosoma mansoni cpg binding protein 0.006 0.0074 0.0073
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0031 0.0454
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0009 0.0008
Brugia malayi sulfakinin receptor protein 0.0019 0.0009 0.0009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0009 0.0008
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0075 0.0074
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0041
Echinococcus granulosus pyruvate kinase 0.0206 0.0304 0.0303
Schistosoma mansoni hypothetical protein 0.0812 0.1254 0.1253
Brugia malayi latrophilin 2 splice variant baaae 0.0192 0.0281 0.028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Brugia malayi nuclear receptor NHR-88 0.0024 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0056
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0017 0.0016
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.638 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0009 0.0008
Brugia malayi Pleckstrin Homology Domain 0.0321 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Echinococcus multilocularis musashi 0.0026 0.0021 0.002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0112 0.0155 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0013 0.0012
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) hhat protein 0.005 0.0058 0.0056
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0011 0.0009
Brugia malayi CHE-14 protein 0.0041 0.0044 0.0044
Schistosoma mansoni sterol O-acyltransferase 1 0.005 0.0058 0.0056
Schistosoma mansoni hypothetical protein 0.0192 0.0281 0.0279
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0016 0.0481
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0009 0.0008
Leishmania major diacylglycerol acyltransferase, putative 0.0739 0.114 1
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0086 0.1244
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0009 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0009 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0017 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0812 0.1254 0.1253
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0235 0.0349 0.0349
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Echinococcus granulosus g protein coupled receptor 0.0019 0.0009 0.0008
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0321 0.0483 0.0482
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0016 0.0481
Loa Loa (eye worm) pigment dispersing factor receptor c 0.028 0.042 0.0418
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0075 0.2429
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0454 0.0692 0.0691
Brugia malayi putative neuropeptide receptor 0.0019 0.0009 0.0009
Brugia malayi p70 ribosomal S6 kinase beta 0.0454 0.0692 0.0692
Onchocerca volvulus 0.0032 0.0031 0.0188
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Entamoeba histolytica hypothetical protein, conserved 0.005 0.0058 0.0817
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0031 0.0454
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0017 0.0017
Schistosoma mansoni opsin-like receptor 0.0019 0.0009 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0075 0.2429
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Onchocerca volvulus 0.0739 0.114 1
Echinococcus multilocularis sterol O acyltransferase 1 0.005 0.0058 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0017 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.0692 0.0691
Echinococcus multilocularis expressed conserved protein 0.009 0.0121 0.012
Brugia malayi Ras association domain family 1 isoform A 0.0321 0.0483 0.0483
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0016 0.0481
Brugia malayi MBOAT family protein 0.005 0.0058 0.0058
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.638 1 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus protein kinase c iota type 0.5149 0.8067 0.8067
Echinococcus multilocularis neutral alpha glucosidase AB 0.0033 0.0031 0.003
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0132 0.0131
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0125 0.0124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Trypanosoma cruzi GUP1, putative 0.005 0.0058 0.0496
Loa Loa (eye worm) hypothetical protein 0.0041 0.0044 0.0043
Brugia malayi Protein kinase domain containing protein 0.0331 0.05 0.0499
Echinococcus granulosus protein kinase C gamma type 0.0454 0.0692 0.0691
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0024 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0017 0.0016
Entamoeba histolytica protein kinase, putative 0.0454 0.0692 1
Trichomonas vaginalis set domain proteins, putative 0.016 0.0232 0.3347
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus Protein kinase C brain isozyme 0.0774 0.1196 0.1195
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0034
Echinococcus multilocularis sex peptide receptor 0.0019 0.0009 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni coup transcription factor 0.0024 0.0017 0.0016
Echinococcus granulosus neuropeptide receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis microtubule associated protein 2 0.0956 0.1482 0.148
Schistosoma mansoni chromobox protein 0.0068 0.0086 0.0085
Echinococcus granulosus pyruvate kinase 0.0206 0.0304 0.0303
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0017 0.0016
Schistosoma mansoni DNA helicase recq5 0.002 0.0011 0.0009
Schistosoma mansoni opsin-like receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0023
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0454 0.0692 0.0691
Leishmania major glycerol uptake protein, putative 0.005 0.0058 0.0496
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0017 0.0071
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0009 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Echinococcus multilocularis tar DNA binding protein 0.0127 0.0179 0.0178
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0009 0.0008
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0075 0.2429
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0009 0.0008
Onchocerca volvulus 0.0086 0.0114 0.0929
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0009 0.0008
Trichomonas vaginalis DNA polymerase eta, putative 0.0014 0.0001 0.002
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0042 0.004
Loa Loa (eye worm) zinc finger protein 0.0321 0.0484 0.0483
Echinococcus granulosus serine:threonine protein kinase N2 0.0454 0.0692 0.0691
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0008
Echinococcus granulosus Diacylglycerol kinase theta 0.0321 0.0483 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.0692 0.0691
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0454 0.0692 0.0691
Echinococcus granulosus neuropeptide s receptor 0.0465 0.071 0.0709
Schistosoma mansoni DNA helicase recq1 0.002 0.0011 0.0009
Brugia malayi diacylglycerol kinase 0.0321 0.0483 0.0483
Onchocerca volvulus Huntingtin homolog 0.0122 0.0172 0.1435
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0009 0.0009
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0454 0.0692 0.0691
Entamoeba histolytica hypothetical protein, conserved 0.0321 0.0484 0.6989
Echinococcus multilocularis protein TFG 0.0321 0.0484 0.0483
Echinococcus granulosus microtubule associated protein 2 0.0956 0.1482 0.148
Schistosoma mansoni smad 0.0019 0.0009 0.0008
Brugia malayi RNA binding protein 0.0127 0.0179 0.0179
Loa Loa (eye worm) AGC/AKT protein kinase 0.0454 0.0692 0.0691
Loa Loa (eye worm) hypothetical protein 0.0122 0.0172 0.017
Brugia malayi RhoGEF domain containing protein 0.0321 0.0483 0.0483
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0016 0.0211
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0011 0.0009
Brugia malayi Melatonin receptor type 1A 0.0019 0.0009 0.0009
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0011 0.0156
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0033 0.0031 0.0183
Onchocerca volvulus 0.0321 0.0483 0.4192
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0134 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0017 0.0016
Trichomonas vaginalis pyruvate kinase, putative 0.0206 0.0304 0.4391
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis pyruvate kinase 0.0206 0.0304 0.0303
Echinococcus granulosus protein kinase c epsilon type 0.0774 0.1196 0.1195
Trypanosoma cruzi GUP1, putative 0.005 0.0058 0.0496
Brugia malayi diacylglycerol acyltransferase 0.0296 0.0444 0.0444
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Echinococcus multilocularis lamin 0.0026 0.0021 0.002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0039 0.0037
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0062 0.0078 0.0078
Brugia malayi G-protein coupled receptor 0.0019 0.0009 0.0009
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) MBOAT family protein 0.005 0.0058 0.0056
Trypanosoma brucei glycerol uptake protein, putative 0.005 0.0058 0.0496
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0021 0.0013 0.0012
Onchocerca volvulus Alhambra homolog 0.0028 0.0024 0.0131
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0009 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0008
Onchocerca volvulus Protein TFG homolog 0.0321 0.0484 0.4199
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0296 0.0444 1
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0075 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0774 0.1196 0.1195
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0089 0.0119 0.0118
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0017 0.0016
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0009 0.0009
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0017 0.0016
Trypanosoma cruzi Aph-1 protein, putative 0.0076 0.01 0.0862
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0017 0.0016
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0331 0.0499 0.0498
Trypanosoma cruzi PAB1-binding protein , putative 0.0042 0.0046 0.0388
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Schistosoma mansoni lamin 0.0026 0.0021 0.002
Loa Loa (eye worm) transcription factor SMAD2 0.0274 0.041 0.0408
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0016 0.0481
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0039 0.0265
Schistosoma mansoni diacylglycerol kinase theta 0.0321 0.0483 0.0482
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0095 0.0094
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0296 0.0444 0.0443
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) beta-glucuronidase 0.0229 0.0339 0.0338
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0031 0.0435
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0317
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0017 0.0017
Echinococcus granulosus orexin receptor type 2 0.0019 0.0009 0.0008
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Schistosoma mansoni biogenic amine receptor 0.0019 0.0009 0.0008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0039 0.0037
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0009 0.0007
Brugia malayi hypothetical protein 0.0134 0.019 0.019
Schistosoma mansoni hypothetical protein 0.0096 0.013 0.0129
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.013
Echinococcus granulosus lamin 0.0026 0.0021 0.002
Brugia malayi hypothetical protein 0.0042 0.0046 0.0045
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0008
Brugia malayi Dopamine receptor protein 1 0.0019 0.0009 0.0009
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0009 0.0008
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0009 0.0008
Onchocerca volvulus 0.016 0.0232 0.1966
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0017 0.0016
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0296 0.0444 0.0443
Leishmania major diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Schistosoma mansoni hypothetical protein 0.0542 0.083 0.0829
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Brugia malayi nuclear hormone receptor 0.0024 0.0017 0.0017
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0011 0.0311
Schistosoma mansoni hypothetical protein 0.0164 0.0237 0.0235
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0444 0.0677 0.9778
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0058 0.0835
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0031 0.0264
Brugia malayi pyruvate kinase 0.0043 0.0048 0.0048
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0009 0.0008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0031 0.0435
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0019 0.001 0.0009
Echinococcus multilocularis serine threonine protein kinase 0.0454 0.0692 0.0691
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0009 0.0008
Brugia malayi Protein kinase c protein 2 0.0331 0.0499 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0367 0.5307
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0016 0.0128
Echinococcus granulosus membrane bound acyltransferase:hhat 0.005 0.0058 0.0056
Toxoplasma gondii histone lysine methyltransferase SET1 0.0109 0.015 0.1237
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.005 0.0058 0.0056
Entamoeba histolytica diacylglycerol kinase, putative 0.0321 0.0483 0.6979
Leishmania major hypothetical protein, conserved 0.0042 0.0046 0.0388
Loa Loa (eye worm) RecQ helicase 0.002 0.0011 0.0009
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0112 0.0155 0.0154
Schistosoma mansoni survival motor neuron protein 0.0096 0.013 0.0129
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0017 0.0016
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis serine:threonine protein kinase 38 0.0454 0.0692 0.0691
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0075 0.0074
Brugia malayi chromobox protein homolog 3 0.0038 0.0039 0.0039
Echinococcus granulosus lysosomal alpha glucosidase 0.0148 0.0213 0.0211
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0321 0.0483 0.0482
Onchocerca volvulus 0.0026 0.0021 0.0102
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0003 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0296 0.0444 0.384
Loa Loa (eye worm) MH2 domain-containing protein 0.0274 0.041 0.0408
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0008 0.0116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0017 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0017 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0009 0.0008
Schistosoma mansoni protein kinase C 0.0321 0.0483 0.0482
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0016 0.0481
Leishmania major glycerol uptake protein, putative 0.005 0.0058 0.0496
Echinococcus multilocularis protein patched 0.0041 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0017 0.0016
Brugia malayi diacylglycerol kinase 0.0321 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.0692 0.0691
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0009 0.0008
Echinococcus granulosus unc 13 munc13 0.0321 0.0483 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0017 0.0017
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0016 0.0481
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0009 0.0008
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0009 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Entamoeba histolytica hypothetical protein 0.0177 0.0258 0.3708
Loa Loa (eye worm) hypothetical protein 0.0023 0.0016 0.0015
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0017 0.0016
Brugia malayi Fli-1 protein 0.0223 0.033 0.033
Leishmania major diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0317
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0321 0.0483 0.0482
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.071 0.0709
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.005 0.0058 0.0056
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni diacylglycerol O-acyltransferase 0.0164 0.0237 0.0235
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0012
Echinococcus granulosus serotonin receptor 0.0019 0.0009 0.0008
Schistosoma mansoni zinc finger protein 0.005 0.0058 0.0056
Trypanosoma cruzi glycerol uptake protein, putative 0.005 0.0058 0.0496
Schistosoma mansoni vav2 0.0321 0.0483 0.0482
Echinococcus granulosus pyruvate kinase 0.0106 0.0146 0.0145
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0016 0.0481
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Echinococcus multilocularis chromobox protein 1 0.0068 0.0086 0.0085
Leishmania major glycerol uptake protein, putative 0.005 0.0058 0.0496
Toxoplasma gondii LsmAD domain-containing protein 0.0042 0.0046 0.0308
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0009 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0016 0.0481
Onchocerca volvulus 0.0134 0.019 0.16
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0179 0.0178
Echinococcus multilocularis pyruvate kinase 0.0106 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0192 0.0281 0.0279
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0179 0.0178
Trypanosoma brucei glucosidase, putative 0.0033 0.0031 0.0264
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0016 0.0016
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0021 0.002
Brugia malayi hypothetical protein 0.047 0.0717 0.0717
Schistosoma mansoni opsin-like receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0774 0.1196 0.1195
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Brugia malayi gamma-secretase subunit aph-1 0.0196 0.0287 0.0287
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0008 0.0116
Echinococcus granulosus tumor protein p63 0.024 0.0357 0.0356
Echinococcus granulosus intermediate filament protein 0.0026 0.0021 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0009 0.0008
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0009 0.0008
Onchocerca volvulus 0.0026 0.0021 0.0102
Loa Loa (eye worm) hypothetical protein 0.0246 0.0366 0.0365
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Onchocerca volvulus 0.0331 0.05 0.4334
Mycobacterium ulcerans pyruvate kinase 0.0206 0.0304 1
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis tumor protein p63 0.024 0.0357 0.0356
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0058 0.0835
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0011 0.0156
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Brugia malayi Pre-SET motif family protein 0.0021 0.0013 0.0013
Toxoplasma gondii dgat2l1-prov protein 0.0739 0.114 1
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0009 0.0008
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0024 0.0118
Schistosoma mansoni pyruvate kinase 0.0106 0.0146 0.0145
Schistosoma mansoni hypothetical protein 0.0028 0.0024 0.0023
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0086 0.0085
Brugia malayi RhoGAP domain containing protein 0.0321 0.0483 0.0483
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0296 0.0444 0.0443
Schistosoma mansoni unc-13 (munc13) 0.0321 0.0483 0.0482
Plasmodium vivax pyruvate kinase 2, putative 0.0106 0.0146 0.3184
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0011 0.0000000001252
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0009 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0009 0.0008
Brugia malayi Serotonin receptor 0.0019 0.0009 0.0009
Onchocerca volvulus 0.0024 0.0017 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Trypanosoma cruzi glycerol uptake protein, putative 0.005 0.0058 0.0496
Trypanosoma cruzi Aph-1 protein, putative 0.0076 0.01 0.0862
Brugia malayi Ets-domain containing protein 0.0073 0.0095 0.0095
Echinococcus granulosus expressed conserved protein 0.009 0.0121 0.012
Brugia malayi Ets-domain containing protein 0.0073 0.0095 0.0095
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0017 0.0017
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0331 0.0499 0.0499
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0016 0.0481
Echinococcus granulosus hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni alpha-glucosidase 0.0128 0.018 0.0179
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.005 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0144 0.0206 0.0204
Trypanosoma brucei pyruvate kinase 1, putative 0.0206 0.0304 0.2657
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0016 0.0015
Echinococcus granulosus chromobox protein 1 0.0068 0.0086 0.0085
Brugia malayi Protein kinase domain containing protein 0.0454 0.0692 0.0692
Echinococcus granulosus g protein coupled receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0002 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0031 0.0454
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0164 0.0237 0.2067
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0017 0.0016
Brugia malayi Heterochromatin protein 1 0.0068 0.0086 0.0086
Toxoplasma gondii AGC kinase 0.0454 0.0692 0.6033
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0017 0.0016
Echinococcus granulosus geminin 0.0542 0.083 0.0829
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0321 0.0483 0.0482
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0075 0.2429
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0009 0.0008
Brugia malayi MBOAT family protein 0.005 0.0058 0.0058
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.013 0.013
Onchocerca volvulus Pyruvate kinase homolog 0.0206 0.0304 0.2605
Echinococcus granulosus chromobox protein 1 0.0068 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.005 0.0058 0.0056
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0296 0.0444 0.384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0042 0.0046 0.0886
Echinococcus multilocularis bloom syndrome protein 0.002 0.0011 0.0009
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0195 0.0193
Plasmodium falciparum phd finger protein, putative 0.0028 0.0024 0.0397
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0017 0.0016
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0321 0.0483 0.0482
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0179 0.0178
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.005 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0044 0.0043
Echinococcus multilocularis Rac GTPase activating protein 1 0.0321 0.0483 0.0482
Loa Loa (eye worm) pyruvate kinase-PB 0.0144 0.0206 0.0204
Chlamydia trachomatis pyruvate kinase 0.0206 0.0304 1
Brugia malayi Dopamine receptor 0.0019 0.0009 0.0009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0148 0.0213 0.0211
Brugia malayi Variant SH3 domain containing protein 0.0321 0.0483 0.0483
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0017 0.0016
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0031 0.0454
Echinococcus multilocularis geminin 0.0542 0.083 0.0829
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0331 0.0499 0.0498
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0454 0.0692 0.0691
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0454 0.0692 0.0691
Brugia malayi protein kinase C3,putative 0.4705 0.737 0.737
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0019 0.0009 0.0008
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.005 0.0058 0.0056
Echinococcus granulosus g protein coupled receptor 0.0019 0.0009 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0024 0.0397
Echinococcus multilocularis protein kinase c epsilon type 0.0774 0.1196 0.1195
Echinococcus granulosus gamma secretase subunit aph 1 0.0196 0.0287 0.0286
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0009 0.0008
Brugia malayi Serotonin receptor 0.0019 0.0009 0.0009
Schistosoma mansoni diacylglycerol O-acyltransferase 0.0164 0.0237 0.0235
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0009 0.0008
Brugia malayi AKH receptor 0.0019 0.0009 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0009 0.0008
Entamoeba histolytica diacylglycerol kinase, putative 0.0321 0.0483 0.6979
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0011 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Onchocerca volvulus 0.0321 0.0484 0.4199
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0009 0.0008
Trichomonas vaginalis sucrase-isomaltase, putative 0.0033 0.0031 0.0454
Brugia malayi Glycosyl hydrolases family 31 protein 0.0033 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Trypanosoma brucei rac serine-threonine kinase, putative 0.0454 0.0692 0.6066
Schistosoma mansoni adenoreceptor 0.0019 0.0009 0.0008
Onchocerca volvulus 0.0023 0.0016 0.0058
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.5027 0.7874 0.7874
Leishmania major pyruvate kinase 0.0206 0.0304 0.2657
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0009 0.0008
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0009 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0017 0.0016
Loa Loa (eye worm) RNA binding protein 0.0127 0.0179 0.0178
Schistosoma mansoni ets-related 0.0223 0.033 0.0329
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0009 0.0008
Echinococcus granulosus fmrfamide receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0001 0.0001
Echinococcus granulosus histone lysine methyltransferase setb 0.0021 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Echinococcus granulosus smad 0.0019 0.0009 0.0008
Brugia malayi PHD-finger family protein 0.0028 0.0024 0.0024
Schistosoma mansoni myosin xvIII 0.0019 0.0009 0.0008
Brugia malayi jmjC domain containing protein 0.0093 0.0125 0.0125
Giardia lamblia Pyruvate kinase 0.0106 0.0146 0.4785
Mycobacterium ulcerans hypothetical protein 0.0164 0.0237 0.7782
Mycobacterium ulcerans hypothetical protein 0.0023 0.0016 0.0481
Schistosoma mansoni patched 1 0.0041 0.0044 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0017 0.0252
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0031 0.0264
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0009 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0009 0.0008
Echinococcus granulosus peregrin 0.0028 0.0024 0.0023
Trichomonas vaginalis glycoside hydrolase, putative 0.0247 0.0367 0.5307
Trypanosoma cruzi pyruvate kinase 2, putative 0.0206 0.0304 0.2657
Schistosoma mansoni smad1 5 8 and 0.0019 0.0009 0.0008
Schistosoma mansoni beta-mannosidase 0.008 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0089 0.0119 0.0118
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0017 0.0071
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0009 0.0009
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0044 0.0634
Brugia malayi MH2 domain containing protein 0.0019 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0321 0.0484 0.4239
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0002 0.0001
Schistosoma mansoni cell polarity protein 0.0321 0.0484 0.0483
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0056
Loa Loa (eye worm) fli-1 protein 0.0223 0.033 0.0329
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0056
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0739 0.114 0.1139
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.071 0.0709
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0112 0.0155 0.0154
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0017 0.0252
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0017 0.0252
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0075 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0017 0.0016
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0195 0.0193
Echinococcus multilocularis unc 13 (munc13) 0.0321 0.0483 0.0482
Trypanosoma cruzi pyruvate kinase 2, putative 0.0206 0.0304 0.2657
Onchocerca volvulus 0.0096 0.013 0.1069
Toxoplasma gondii mono- or diacylglycerol acyltransferase 0.0164 0.0237 0.2001
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Echinococcus granulosus cpg binding protein 0.006 0.0074 0.0073
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0089 0.0119 0.0118
Brugia malayi Hr1 repeat family protein 0.0454 0.0692 0.0692
Echinococcus granulosus neutral alpha glucosidase AB 0.0033 0.0031 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0499 0.0498
Entamoeba histolytica pyruvate kinase, putative 0.0144 0.0206 0.296
Echinococcus multilocularis pyruvate kinase 0.0106 0.0146 0.0145
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0089 0.0119 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0774 0.1196 0.1195
Schistosoma mansoni unc-13 (munc13) 0.0322 0.0486 0.0485
Entamoeba histolytica hypothetical protein 0.0177 0.0258 0.3708
Echinococcus granulosus dnaJ subfamily B 0.0812 0.1254 0.1253
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0021 0.0013 0.0021
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.071 0.0709
Loa Loa (eye worm) hypothetical protein 0.0149 0.0213 0.0212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0017 0.0017
Echinococcus multilocularis pyruvate kinase 0.0163 0.0236 0.0234
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.004 0.0042 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0017 0.0017
Brugia malayi pyruvate kinase, muscle isozyme 0.0043 0.0048 0.0048
Brugia malayi GnHR receptor homolog 0.0019 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0013 0.0012
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0017 0.0016
Plasmodium vivax ataxin-2 like protein, putative 0.0042 0.0046 0.0886
Brugia malayi Cytochrome P450 family protein 0.0048 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0039 0.0038
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0021 0.002
Toxoplasma gondii pyruvate kinase PyK1 0.0206 0.0304 0.2595
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0112 0.0155 0.0154
Loa Loa (eye worm) MBOAT family protein 0.005 0.0058 0.0056
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0321 0.0483 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0235 0.0349 0.0348
Echinococcus granulosus o acyltransferase membrane bound domain 0.005 0.0058 0.0056
Brugia malayi neuropeptide F receptor 0.0019 0.0009 0.0009
Entamoeba histolytica recQ family helicase, putative 0.002 0.0011 0.0136
Loa Loa (eye worm) hypothetical protein 0.0089 0.0119 0.0118
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0002 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.0177 0.0258 0.0256
Brugia malayi diacylglycerol acyltransferase family protein 0.0739 0.114 0.114
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0016 0.0128
Leishmania major glycerol uptake protein, putative 0.005 0.0058 0.0496
Brugia malayi Smad1 0.0019 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Leishmania major glycerol uptake protein, putative 0.005 0.0058 0.0496
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0017 0.0252
Brugia malayi ORL1-like opioid receptor 0.0019 0.0009 0.0009
Echinococcus granulosus lamin dm0 0.0026 0.0021 0.002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0069 0.0068
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0112 0.0155 0.0154
Schistosoma mansoni diacylglycerol kinase theta 0.0321 0.0483 0.0482
Echinococcus multilocularis smad 0.0019 0.0009 0.0008
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0009 0.0008
Brugia malayi Pyruvate kinase, muscle isozyme 0.0206 0.0304 0.0304
Schistosoma mansoni histamine h1 receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis Smad4 0.0019 0.0009 0.0008
Loa Loa (eye worm) hhat protein 0.005 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Echinococcus multilocularis lamin dm0 0.0026 0.0021 0.002
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0024 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0179 0.0178
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0141 0.0201 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0116 0.1674
Onchocerca volvulus 0.005 0.0058 0.0429
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0125 0.0124
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0774 0.1196 0.1195
Echinococcus multilocularis protein kinase c eta type 0.0321 0.0483 0.0482
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.005 0.0058 0.0056
Trypanosoma brucei PB1 domain containing protein, putative 0.0321 0.0484 0.4239
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0017 0.0016
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0011 0.0009
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0044 0.0043
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0009 0.0008
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0021 0.0013 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0008
Trypanosoma brucei PAB1-binding protein , putative 0.0042 0.0046 0.0388
Echinococcus granulosus protein kinase c eta type 0.0321 0.0483 0.0482
Echinococcus multilocularis GPCR, family 2 0.0089 0.0119 0.0118
Trypanosoma cruzi glycerol uptake protein, putative 0.005 0.0058 0.0496
Schistosoma mansoni atypical protein kinase C 0.5471 0.8571 0.8571
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0009 0.0008
Brugia malayi hypothetical protein 0.0177 0.0258 0.0257
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0044 0.0043
Entamoeba histolytica hypothetical protein 0.005 0.0058 0.0817
Loa Loa (eye worm) RasGEF domain-containing protein 0.0321 0.0483 0.0482
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0019 0.0009 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0042 0.0046 0.0886
Schistosoma mansoni hypothetical protein 0.0089 0.0119 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0016
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0044 0.0305
Loa Loa (eye worm) hypothetical protein 0.0321 0.0483 0.0482
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0044
Toxoplasma gondii hypothetical protein 0.005 0.0058 0.0417
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0033 0.0031 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.013
Brugia malayi CHD4 protein 0.0014 0.0002 0.0002
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Echinococcus granulosus bloom syndrome protein 0.002 0.0011 0.0009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.028 0.042 0.0419
Schistosoma mansoni hypothetical protein 0.0089 0.0119 0.0118
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0196 0.0287 0.0286
Brugia malayi Partitioning defective-6 homolog alpha 0.0321 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0008
Schistosoma mansoni alpha-glucosidase 0.0128 0.018 0.0179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0017 0.0016
Leishmania major hypothetical protein, conserved 0.005 0.0058 0.0496
Leishmania major hypothetical protein, unknown function,protein, unknown function 0.0164 0.0237 0.2067
Echinococcus multilocularis pyruvate kinase 0.0106 0.0146 0.0145
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.013 0.1863
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0454 0.0692 1
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0009 0.0008
Schistosoma mansoni biogenic amine receptor 0.0019 0.0009 0.0008
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0774 0.1196 0.1195
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0039 0.0569
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0017 0.0071
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0017 0.0017
Echinococcus granulosus tar DNA binding protein 0.0127 0.0179 0.0178
Echinococcus multilocularis somatostatin receptor 0.0019 0.0009 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0483 0.0482
Echinococcus multilocularis myotubularin protein 13 0.0321 0.0483 0.0482
Loa Loa (eye worm) AGC/NDR protein kinase 0.0454 0.0692 0.0691
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0014 0.0001 0.002
Plasmodium vivax SET domain protein, putative 0.0021 0.0013 0.0146
Entamoeba histolytica hypothetical protein 0.0177 0.0258 0.3708
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0017 0.0017
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0331 0.05 0.0498
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0003 0.0002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0011 0.0011
Onchocerca volvulus 0.0321 0.0483 0.4192
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0009 0.0008
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0009 0.0008
Giardia lamblia Pyruvate kinase 0.0206 0.0304 1
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0009 0.0008

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 6.25 ug ml-1 Antibacterial activity against Escherichia coli NCIM 2065 assessed as growth inhibition after 24 hr by NCCLS broth dilution method ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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