Detailed information for compound 229957

Basic information

Technical information
  • TDR Targets ID: 229957
  • Name: 1-(1-benzothiophen-3-yl)-3-(4-quinolin-2-ylpi perazin-1-yl)propan-1-ol
  • MW: 403.54 | Formula: C24H25N3OS
  • H donors: 1 H acceptors: 2 LogP: 4.68 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(c1csc2c1cccc2)CCN1CCN(CC1)c1ccc2c(n1)cccc2
  • InChi: 1S/C24H25N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,28H,11-16H2
  • InChiKey: QIIWIJVYPXMMIG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(benzothiophen-3-yl)-3-[4-(2-quinolyl)piperazin-1-yl]propan-1-ol
  • 1-(3-benzothiophenyl)-3-[4-(2-quinolyl)-1-piperazinyl]-1-propanol
  • 1-(benzothiophen-3-yl)-3-[4-(2-quinolyl)piperazino]propan-1-ol
  • 1-(3-benzothiophenyl)-3-[4-(2-quinolyl)-1-piperazinyl]propan-1-ol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Serotonin transporter Starlite/ChEMBL References
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1a (5-HT1a) receptor   422 aa 417 aa 21.1 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 390 aa 33.6 %
Loa Loa (eye worm) TYRA-2 protein Serotonin 1a (5-HT1a) receptor   422 aa 491 aa 27.3 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1a (5-HT1a) receptor   422 aa 392 aa 20.7 %
Onchocerca volvulus Serotonin transporter   630 aa 611 aa 26.4 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Serotonin transporter   630 aa 581 aa 40.1 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Serotonin 1a (5-HT1a) receptor   422 aa 410 aa 27.8 %
Loa Loa (eye worm) hypothetical protein Serotonin 1a (5-HT1a) receptor   422 aa 388 aa 26.5 %
Echinococcus multilocularis neuropeptides capa receptor Serotonin 1a (5-HT1a) receptor   422 aa 430 aa 20.0 %
Onchocerca volvulus Transmembrane protein 120 homolog Serotonin transporter   630 aa 571 aa 31.2 %
Echinococcus granulosus g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 24.3 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Serotonin transporter   630 aa 629 aa 47.1 %
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor Serotonin 1a (5-HT1a) receptor   422 aa 350 aa 20.6 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 576 aa 31.8 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 582 aa 35.2 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Serotonin 1a (5-HT1a) receptor   422 aa 448 aa 29.7 %
Plasmodium vivax hypothetical protein, conserved Serotonin transporter   630 aa 528 aa 21.2 %
Schistosoma japonicum Octopamine receptor 1, putative Serotonin 1a (5-HT1a) receptor   422 aa 424 aa 24.3 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 436 aa 23.9 %
Schistosoma mansoni sodium/chloride dependent transporter Serotonin transporter   630 aa 552 aa 41.5 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Serotonin transporter   630 aa 585 aa 34.2 %
Brugia malayi Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 576 aa 30.9 %
Echinococcus multilocularis orexin receptor type 2 Serotonin 1a (5-HT1a) receptor   422 aa 369 aa 22.2 %
Echinococcus granulosus g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 23.4 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Serotonin transporter   630 aa 520 aa 36.2 %
Echinococcus multilocularis sodium and chloride dependent glycine Serotonin transporter   630 aa 617 aa 39.4 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 407 aa 23.3 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Serotonin 1a (5-HT1a) receptor   422 aa 383 aa 30.5 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Serotonin 1a (5-HT1a) receptor   422 aa 339 aa 23.0 %
Echinococcus granulosus sodium and chloride dependent glycine Serotonin transporter   630 aa 617 aa 39.4 %
Schistosoma mansoni sodium/chloride dependent transporter Serotonin transporter   630 aa 605 aa 37.7 %
Echinococcus granulosus orexin receptor type 2 Serotonin 1a (5-HT1a) receptor   422 aa 369 aa 22.0 %
Schistosoma mansoni amine GPCR Serotonin 1a (5-HT1a) receptor   422 aa 440 aa 31.6 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 23.6 %
Plasmodium knowlesi transporter, putative Serotonin transporter   630 aa 514 aa 20.2 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 426 aa 29.6 %
Echinococcus granulosus alpha 1A adrenergic receptor Serotonin 1a (5-HT1a) receptor   422 aa 452 aa 21.0 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 509 aa 28.3 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 433 aa 22.4 %
Onchocerca volvulus Glycoprotein hormone beta 5 homolog Serotonin 1a (5-HT1a) receptor   422 aa 477 aa 24.3 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Serotonin 1a (5-HT1a) receptor   422 aa 444 aa 29.3 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Serotonin transporter   630 aa 638 aa 25.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum hexose transporter 0.0557 0.5968 0.5963
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.0409 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.1766 0.2946
Schistosoma mansoni hypothetical protein 0.0172 0.1755 0.2928
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0294 0.0474
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0045 0.0365 0.2017
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0352 0.373 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0035 0.0025
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0012 0.0013 0.0001
Plasmodium vivax sugar transporter, putative 0.0078 0.0733 0.0723
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0294 0.0294
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0332 0.1829
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0076 0.0711 0.1075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Giardia lamblia Hexose transporter 0.0078 0.0733 0.1942
Giardia lamblia DNA repair protein RAD52 0.0352 0.373 1
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0035 0.004
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.006 0.0538 0.0528
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0294 0.0294
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0276 0.0275
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0304 0.0492
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.01 0.0973 0.2587
Loa Loa (eye worm) hypothetical protein 0.002 0.0095 0.014
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0038 0.0027
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0276 0.0275
Schistosoma mansoni hypothetical protein 0.0016 0.0052 0.0068
Schistosoma mansoni amine GPCR 0.0038 0.0294 0.0474
Leishmania major telomerase reverse transcriptase, putative 0.0082 0.0776 0.4356
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0259 0.1412
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0276 0.151
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0276 0.1829
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0012 0.0013 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Leishmania major DNA polymerase kappa, putative 0.0021 0.0111 0.0566
Schistosoma mansoni opsin-like receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) beta-lactamase 0.0036 0.0276 0.0445
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0073 0.0675 0.1115
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0035 0.0025
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0086 0.0428
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0276 0.1829
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0061 0.0283
Brugia malayi beta-lactamase family protein 0.0036 0.0276 0.0445
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0711 0.3989
Brugia malayi putative neuropeptide receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0044
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.0409 0.0399
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0294 0.0294
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0065 0.0593 0.0976
Schistosoma mansoni neuropeptide receptor 0.0038 0.0294 0.0474
Echinococcus multilocularis calcium dependent protein kinase 0.0063 0.0562 0.0572
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0035 0.004
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.0409 0.2749
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0733 0.1212
Treponema pallidum fructose-bisphosphate aldolase 0.0296 0.3116 1
Onchocerca volvulus 0.0078 0.0733 0.2286
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Toxoplasma gondii DNA polymerase 0.0019 0.0086 0.0131
Toxoplasma gondii transporter, major facilitator family protein 0.0078 0.0733 0.1109
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0294 0.0474
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0111 0.0566
Onchocerca volvulus 0.0038 0.0294 0.0892
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0294 0.0474
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0294 0.0294
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0035 0.0025
Trypanosoma brucei glucose transporter 1E 0.0173 0.1766 1
Leishmania major hypothetical protein, conserved 0.0078 0.0733 0.4116
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Brugia malayi Major Facilitator Superfamily protein 0.0078 0.0733 0.1212
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0038 0.0294 0.0474
Leishmania major glucose transporter, lmgt1 0.0173 0.1766 1
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0294 0.0294
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0078 0.0733 0.4987
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Plasmodium vivax proline--tRNA ligase, putative 0.0076 0.0711 0.0701
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0035 0.0025
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0014 0.0035 0.004
Onchocerca volvulus 0.0078 0.0733 0.2286
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0166 0.0155
Trypanosoma brucei THT1 - hexose transporter, putative 0.0173 0.1766 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0294 0.0294
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0294 0.0294
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0294 0.0474
Echinococcus multilocularis GPCR, family 2 0.0016 0.0052 0.0042
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.0409 0.0669
Onchocerca volvulus 0.0014 0.0035 0.0071
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0893 0.9639 1
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0019 0.0086 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0294 0.0294
Brugia malayi Telomerase reverse transcriptase 0.0219 0.2268 0.3789
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Giardia lamblia DINP protein human, muc B family 0.0021 0.0111 0.0267
Schistosoma mansoni protein kinase 0.0067 0.0607 0.1001
Trypanosoma cruzi hexose transporter, putative 0.0078 0.0733 0.4116
Entamoeba histolytica protein kinase, putative 0.0067 0.0607 0.1603
Toxoplasma gondii DNA polymerase family B protein 0.0019 0.0086 0.0131
Schistosoma mansoni biogenic amine (5HT) receptor 0.032 0.3379 0.5654
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0294 0.0294
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.0409 0.0414
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0014 0.0035 0.0025
Onchocerca volvulus 0.0078 0.0733 0.2286
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0276 0.0445
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0294 0.0474
Mycobacterium tuberculosis Conserved protein 0.0036 0.0276 0.1097
Leishmania major hypothetical protein, conserved 0.0036 0.0276 0.151
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Echinococcus multilocularis solute carrier family 22 0.0078 0.0733 0.075
Onchocerca volvulus 0.0038 0.0294 0.0892
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0019 0.0086 0.0078
Echinococcus granulosus synaptic vesicle 2 protein 0.0078 0.0733 0.075
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0166 0.016
Schistosoma mansoni neuropeptide receptor 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0038 0.0294 0.0892
Trypanosoma brucei DNA polymerase eta, putative 0.0015 0.0038 0.015
Plasmodium vivax hexose transporter 0.0557 0.5968 0.5963
Trypanosoma brucei THT1 - hexose transporter, putative 0.0173 0.1766 1
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0065 0.0593 0.1563
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0019 0.0086 0.0126
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0294 0.0474
Trypanosoma cruzi glucose transporter, putative 0.0078 0.0733 0.4116
Onchocerca volvulus 0.0038 0.0294 0.0892
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0294 0.0474
Trichomonas vaginalis myo-inositol transporter, putative 0.0078 0.0733 0.1212
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0294 0.0294
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) LGC-31 protein 0.0014 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Plasmodium vivax telomerase reverse transcriptase, putative 0.0082 0.0776 0.0765
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0067 0.0607 0.1001
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0078 0.0733 0.299
Brugia malayi lysyl-tRNA synthetase 0.0049 0.0409 0.0669
Loa Loa (eye worm) hypothetical protein 0.0073 0.0675 0.1115
Schistosoma mansoni sugar transporter 0.0078 0.0733 0.1212
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0038 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.043 0.0702
Giardia lamblia Prolyl-tRNA synthetase 0.0065 0.0593 0.1563
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0294 0.0474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Echinococcus multilocularis nAChR subunit 0.0014 0.0035 0.0025
Treponema pallidum sodium- and chloride- dependent transporter 0.0073 0.0675 0.2139
Treponema pallidum ATP-dependent DNA helicase 0.002 0.0095 0.0269
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0095 0.0143
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0035 0.004
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0087 0.0202
Schistosoma mansoni sodium-dependent amino acid transporter 0.0012 0.0013 0.0002
Brugia malayi beta-lactamase family protein 0.0036 0.0276 0.0445
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0012 0.0013 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.0329 0.1316
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0294 0.0294
Brugia malayi major facilitator superfamily protein 0.0078 0.0733 0.1212
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0052 0.0068
Plasmodium falciparum telomerase reverse transcriptase 0.0082 0.0776 0.0765
Echinococcus multilocularis sex peptide receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) RecQ helicase 0.0066 0.0599 0.0987
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0052 0.0042
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0014 0.0035 0.004
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0038 0.015
Onchocerca volvulus 0.0036 0.0276 0.0836
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0012 0.0013 0.0001
Schistosoma mansoni glucose transport protein 0.0557 0.5968 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0276 0.151
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0019
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.3116 0.835
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0052 0.0068
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0294 0.0294
Onchocerca volvulus 0.0014 0.0035 0.0071
Schistosoma mansoni protein kinase 0.0067 0.0607 0.1001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0409 0.0669
Onchocerca volvulus Putative transporter 0.0078 0.0733 0.2286
Onchocerca volvulus 0.0078 0.0733 0.2286
Leishmania major glucose transporter, lmgt2 0.0173 0.1766 1
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0294 0.0294
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0276 0.0445
Plasmodium falciparum calcium-dependent protein kinase 4 0.0067 0.0608 0.0597
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) major facilitator superfamily transporter 0.0078 0.0733 0.1212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Onchocerca volvulus 0.0073 0.0675 0.2101
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0166 0.0259
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0019 0.0086 0.0234
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0035 0.0025
Trypanosoma brucei unspecified product 0.0035 0.0259 0.1412
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Plasmodium falciparum proline--tRNA ligase 0.0076 0.0711 0.0701
Trypanosoma cruzi hexose transporter, putative 0.0173 0.1766 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Onchocerca volvulus Putative nachr subunit 0.0014 0.0035 0.0071
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Mycobacterium ulcerans hypothetical protein 0.0036 0.0276 0.1829
Schistosoma mansoni protein kinase 0.0067 0.0607 0.1001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0126
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0014 0.0035 0.0071
Schistosoma mansoni biogenic amine receptor 0.0038 0.0294 0.0474
Echinococcus granulosus biogenic amine 5HT receptor 0.032 0.3379 0.3498
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0294 0.0294
Echinococcus granulosus calcium dependent protein kinase 0.0063 0.0562 0.0572
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0294 0.0294
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0014 0.0035 0.0025
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0035 0.004
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.0409 0.2269
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0019 0.0086 0.0202
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.013 0.0382
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0019 0.0086 0.0078
Giardia lamblia Sugar-proton symporter 0.0078 0.0733 0.1942
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Loa Loa (eye worm) norepinephrine transporter 0.0073 0.0675 0.1115
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.0409 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0078 0.0733 0.1212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0711 0.3989
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni hypothetical protein 0.0016 0.0052 0.0068
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0038 0.0027
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0294 0.0474
Onchocerca volvulus DNA polymerase homolog 0.0019 0.0086 0.0234
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0109 0.1073 0.1783
Brugia malayi larval opioid receptor 0.0038 0.0294 0.0474
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0019 0.0086 0.0075
Schistosoma mansoni adenoreceptor 0.0038 0.0294 0.0474
Schistosoma mansoni myosin xvIII 0.0038 0.0294 0.0474
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0061 0.0283
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0067 0.0608 0.0919
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0058 0.0079
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0329 0.2195
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0035 0.004
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0035 0.004
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.0409 0.1071
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.032 0.3379 0.5654
Brugia malayi Bloom's syndrome protein homolog 0.0066 0.0599 0.0987
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0294 0.0294
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0019 0.0086 0.0126
Echinococcus granulosus solute carrier family 22 0.0078 0.0733 0.075
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Schistosoma mansoni glucose transport protein 0.0557 0.5968 1
Plasmodium falciparum transporter, putative 0.0012 0.0013 0.0001
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0067 0.0608 0.0597
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0078 0.0733 0.1212
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.0409 0.2269
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0038 0.0294 0.0892
Brugia malayi Melatonin receptor type 1A 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0038 0.0294 0.0892
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Schistosoma mansoni amine GPCR 0.0038 0.0294 0.0474
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0294 0.0474
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.0409 0.0399
Echinococcus multilocularis serotonin receptor 0.032 0.3379 0.3498
Echinococcus granulosus geminin 0.0172 0.1755 0.1811
Echinococcus granulosus allatostatin A receptor 0.0038 0.0294 0.0294
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0014 0.0035 0.004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.043 0.0702
Entamoeba histolytica recQ family DNA helicase 0.002 0.0095 0.0225
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0276 0.0265
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0166 0.0259
Brugia malayi DNA polymerase alpha catalytic subunit 0.0019 0.0086 0.0126
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0332 0.0333
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0276 0.1097
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0019 0.0086 0.0078
Echinococcus granulosus solute carrier family 22 0.0078 0.0733 0.075
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0294 0.0474
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0276 0.0445
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0111 0.0411
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.032 0.3379 0.5654
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0294 0.0474
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Schistosoma mansoni sodium/chloride dependent transporter 0.0073 0.0675 0.1115
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0222 0.1199
Loa Loa (eye worm) sugar transporter 0.0078 0.0733 0.1212
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0893 0.9639 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0038 0.0109
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0276 0.1097
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0352 0.3731 0.564
Trichomonas vaginalis sugar transporter, putative 0.0173 0.1766 0.2946
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0019 0.0086 0.0202
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0019 0.0086 0.0428
Onchocerca volvulus 0.0036 0.0276 0.0836
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0035 0.004
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0294 0.0294
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0409 0.2749
Echinococcus multilocularis solute carrier family 22 0.0078 0.0733 0.075
Echinococcus granulosus General substrate transporter 0.0479 0.5111 0.5297
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0035 0.0025
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0035 0.0025
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0294 0.0474
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus granulosus somatostatin receptor 0.0038 0.0294 0.0294
Onchocerca volvulus 0.0038 0.0294 0.0892
Toxoplasma gondii sugar transporter ST3 0.0078 0.0733 0.1109
Mycobacterium leprae Probable lipase LipE 0.0036 0.0276 0.1829
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0019 0.0086 0.0078
Echinococcus granulosus g protein coupled receptor 0.0038 0.0294 0.0294
Schistosoma mansoni histamine h1 receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0014 0.0035 0.0071
Brugia malayi hypothetical protein 0.0078 0.0733 0.1212
Onchocerca volvulus 0.0078 0.0733 0.2286
Schistosoma mansoni hypothetical protein 0.0557 0.5968 1
Plasmodium vivax DNA polymerase alpha, putative 0.0019 0.0086 0.0075
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0012 0.0013 0.0002
Giardia lamblia Sgs1 DNA helicase, putative 0.0039 0.0304 0.0788
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0012 0.0013 0.0001
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0012 0.0013 0.0001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0052 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Trichomonas vaginalis esterase, putative 0.0036 0.0276 0.0445
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.146 1
Brugia malayi Dopamine receptor protein 2 0.0038 0.0294 0.0474
Trichomonas vaginalis DNA helicase recq1, putative 0.0066 0.0599 0.0987
Brugia malayi G-protein coupled receptor 0.0038 0.0294 0.0474
Schistosoma mansoni hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0294 0.0474
Brugia malayi RE15519p 0.0038 0.0294 0.0474
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Brugia malayi DNA polymerase delta catalytic subunit 0.0019 0.0086 0.0126
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Trypanosoma cruzi hexose transporter, putative 0.0173 0.1766 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0012 0.0013 0.0002
Schistosoma mansoni neuropeptide receptor 0.0038 0.0294 0.0474
Leishmania major protein kinase, putative 0.0067 0.0607 0.3398
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0095 0.0476
Echinococcus granulosus bloom syndrome protein 0.0066 0.0599 0.0611
Toxoplasma gondii ABC1 family protein 0.0036 0.0276 0.0417
Schistosoma mansoni hypothetical protein 0.0016 0.0052 0.0068
Giardia lamblia Fructose-bisphosphate aldolase 0.0296 0.3116 0.835
Entamoeba histolytica deoxycytidyl transferase, putative 0.0015 0.0038 0.0071
Echinococcus granulosus nAChR subunit 0.0014 0.0035 0.0025
Brugia malayi AKH receptor 0.0038 0.0294 0.0474
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0019
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0329 0.1316
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0294 0.0294
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0276 0.151
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0332 0.2216
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Echinococcus multilocularis solute carrier family 22 0.0078 0.0733 0.075
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0014 0.0035 0.004
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0067 0.0608 0.0597
Loa Loa (eye worm) hypothetical protein 0.0465 0.4966 0.8319
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0294 0.0294
Echinococcus granulosus transcription factor eb 0.0109 0.1073 0.1103
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Trichomonas vaginalis DNA polymerase II, putative 0.0019 0.0086 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0294 0.0294
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0711 0.3989
Loa Loa (eye worm) hypothetical protein 0.0465 0.4966 0.8319
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0019 0.0086 0.0126
Schistosoma mansoni sugar transporter 0.0078 0.0733 0.1212
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0035 0.0025
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0036 0.0276 0.0445
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0014 0.0035 0.004
Echinococcus granulosus neuropeptide receptor 0.0038 0.0294 0.0294
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0036 0.0276 0.0836
Brugia malayi Major Facilitator Superfamily protein 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.015 0.1517 0.2528
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0052 0.0068
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0016 0.0052 0.0068
Echinococcus multilocularis transcription factor eb 0.0109 0.1073 0.1103
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0304 0.046
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0073 0.0675 0.1115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0294 0.0294
Trypanosoma cruzi hexose transporter, putative 0.0173 0.1766 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0078 0.0733 0.299
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0035 0.004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0052 0.0042
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0065 0.0593 0.0976
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0065 0.0593 0.0976
Schistosoma mansoni opsin-like receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.0409 0.2269
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.013 0.2978
Toxoplasma gondii sugar transporter ST2 0.0078 0.0733 0.1109
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0019 0.0086 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0014 0.0035 0.004
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0365 0.0594
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0294 0.0294
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0166 0.088
Toxoplasma gondii protein kinase, putative 0.0616 0.6616 1
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0078 0.0733 0.075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0012 0.0013 0.0001
Brugia malayi Sugar transporter family protein 0.0078 0.0733 0.1212
Plasmodium falciparum calcium-dependent protein kinase 2 0.0067 0.0608 0.0597
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0095 0.014
Brugia malayi beta-lactamase 0.0036 0.0276 0.0445
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0039 0.0304 0.0304
Mycobacterium tuberculosis Conserved protein 0.0036 0.0276 0.1097
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Onchocerca volvulus 0.0038 0.0294 0.0892
Onchocerca volvulus 0.0014 0.0035 0.0071
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0019 0.0086 0.0075
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0082 0.0776 0.4356
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0019 0.0086 0.0126
Echinococcus granulosus sodium and chloride dependent glycine 0.0012 0.0013 0.0001
Echinococcus granulosus hypothetical protein 0.0038 0.0294 0.0294
Plasmodium vivax amine transporter, putative 0.0012 0.0013 0.0001
Echinococcus granulosus fmrfamide receptor 0.0038 0.0294 0.0294
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0014 0.0035 0.0025
Onchocerca volvulus 0.0038 0.0294 0.0892
Loa Loa (eye worm) hypothetical protein 0.0036 0.0276 0.0445
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0035 0.0025
Trichomonas vaginalis glucose transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni amine GPCR 0.0405 0.4311 0.7219
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Mycobacterium ulcerans beta-lactamase 0.0036 0.0276 0.1829
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0076 0.0711 0.3989
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0035 0.0025
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0166 0.0415
Trichomonas vaginalis sugar transporter, putative 0.0173 0.1766 0.2946
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Mycobacterium tuberculosis Conserved protein 0.0036 0.0276 0.1097
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0012 0.0013 0.0002
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0011 0.0017
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0294 0.0294
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0321 0.0485
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0294 0.0294
Schistosoma mansoni DNA helicase recq1 0.0039 0.0304 0.0492
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.146 0.5996
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0061 0.0283
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0012 0.0013 0.0002
Trichomonas vaginalis sugar transport protein, putative 0.0078 0.0733 0.1212
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0344 0.0558
Plasmodium falciparum calcium-dependent protein kinase 3 0.0067 0.0608 0.0597
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0014 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Trypanosoma brucei THT1 - hexose transporter, putative 0.0173 0.1766 1
Toxoplasma gondii RNA-directed DNA polymerase 0.0082 0.0776 0.1172
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0014 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0276 0.0445
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Brugia malayi Cation transporter family protein 0.0014 0.0035 0.004
Trypanosoma brucei telomerase reverse transcriptase 0.0082 0.0776 0.4356
Toxoplasma gondii hypothetical protein 0.0012 0.0013 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Brugia malayi Cation transporter family protein 0.0014 0.0035 0.004
Entamoeba histolytica protein kinase, putative 0.0067 0.0607 0.1603
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0035 0.004
Brugia malayi Serotonin receptor 0.0038 0.0294 0.0474
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0067 0.0608 0.0597
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Schistosoma mansoni amine GPCR 0.0038 0.0294 0.0474
Echinococcus granulosus solute carrier family 22 0.0078 0.0733 0.075
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0019 0.0087 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0733 0.1212
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0304 0.046
Schistosoma mansoni blooms syndrome DNA helicase 0.0046 0.0382 0.0622
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0039 0.0304 0.0304
Schistosoma mansoni opsin-like receptor 0.0038 0.0294 0.0474
Schistosoma mansoni glucose transport protein 0.0557 0.5968 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0276 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0557 0.5968 1
Brugia malayi Cam kinase protein 1 0.0067 0.0607 0.1001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0173 0.1766 0.2946
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0039 0.0304 0.0293
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0294 0.0294
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0012 0.0013 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0012 0.0013 0.0002
Trypanosoma cruzi hexose transporter, putative 0.0094 0.091 0.512
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0073 0.0675 0.1115
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0294 0.0474
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Schistosoma mansoni sugar transporter 0.0078 0.0733 0.1212
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0014 0.0035 0.004
Brugia malayi sulfakinin receptor protein 0.0038 0.0294 0.0474
Echinococcus multilocularis sodium and chloride dependent glycine 0.0012 0.0013 0.0001
Schistosoma mansoni hypothetical protein 0.0035 0.0255 0.0409
Plasmodium falciparum calcium-dependent protein kinase 5 0.0067 0.0608 0.0597
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0294 0.0474
Echinococcus granulosus Sugar transporter ERD6 protein 0.0078 0.0733 0.075
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0294 0.0294
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis synaptic vesicle 2 protein 0.0078 0.0733 0.075
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0557 0.5968 0.902
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0294 0.0294
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0012 0.0013 0.0002
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0171 0.0268
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0409 0.0669
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0035 0.004
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0078 0.0733 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0035 0.0025
Echinococcus granulosus dna polymerase eta 0.0015 0.0038 0.0027
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0294 0.0294
Entamoeba histolytica hypothetical protein 0.0049 0.0409 0.1071
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0045 0.0365 0.2017
Loa Loa (eye worm) sugar transporter 0.0557 0.5968 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Trichomonas vaginalis sugar transporter, putative 0.0173 0.1766 0.2946
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0301 0.3167 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0065 0.0593 0.0976
Onchocerca volvulus 0.0038 0.0294 0.0892
Loa Loa (eye worm) hypothetical protein 0.0053 0.0458 0.0751
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0294 0.0294
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0036 0.0276 0.0445
Loa Loa (eye worm) hypothetical protein 0.0067 0.0607 0.1001
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Plasmodium falciparum mitogen-activated protein kinase 2 0.0352 0.3731 0.3724
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0294 0.0294
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0067 0.0608 0.0919
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0166 0.0415
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Brugia malayi Dopamine receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) solute carrier family 6 member 4 0.0073 0.0675 0.1115
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0019 0.0086 0.0202
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0019 0.0086 0.0078
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0332 0.0539
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0294 0.0294
Brugia malayi Flap endonuclease-1 0.0026 0.0166 0.0259
Leishmania major myo-inositol/proton symporter (MIT) 0.0078 0.0733 0.4116
Schistosoma mansoni hypothetical protein 0.0172 0.1755 0.2928
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0019 0.0086 0.0428
Echinococcus granulosus neuropeptide receptor 0.0038 0.0294 0.0294
Echinococcus granulosus g protein coupled receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0019 0.0086 0.0126
Echinococcus granulosus orexin receptor type 2 0.0038 0.0294 0.0294
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0002
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0019 0.0086 0.0428
Giardia lamblia Telomerase catalytic subunit 0.0082 0.0776 0.2055
Loa Loa (eye worm) hypothetical protein 0.0065 0.0593 0.0976
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0019 0.0086 0.0075
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0012 0.0013 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Brugia malayi Dopamine receptor protein 1 0.0038 0.0294 0.0474
Schistosoma mansoni sugar transporter 0.0078 0.0733 0.1212
Schistosoma mansoni glucose transporter 0.0078 0.0733 0.1212
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Brugia malayi neuropeptide F receptor 0.0038 0.0294 0.0474
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus granulosus serotonin receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Brugia malayi polk-prov protein 0.0032 0.0222 0.0353
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0294 0.0294
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Brugia malayi neuropeptide F receptor 0.0038 0.0294 0.0474
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.0409 0.0619
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Onchocerca volvulus 0.0078 0.0733 0.2286
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0038 0.0044
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0019 0.0086 0.0078
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0082 0.0776 0.4356
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0409 0.2749
Brugia malayi follicle stimulating hormone receptor 0.0038 0.0294 0.0474
Schistosoma mansoni biogenic amine receptor 0.0038 0.0294 0.0474
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0035 0.004
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0294 0.0474
Echinococcus multilocularis solute carrier family 22 0.0078 0.0733 0.075
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0035 0.004
Entamoeba histolytica hypothetical protein 0.01 0.0973 0.2587
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0294 0.0294
Brugia malayi G-protein coupled receptor 0.0038 0.0294 0.0474
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0012 0.0013 0.0002
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0011 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0078 0.0733 0.2286
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0014 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Schistosoma mansoni flap endonuclease-1 0.0024 0.0138 0.0213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Schistosoma mansoni hypothetical protein 0.0038 0.0294 0.0474
Schistosoma mansoni DNA polymerase eta 0.0015 0.0038 0.0044
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0019 0.0086 0.0126
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.2427 1
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0065 0.0593 0.0604
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0078 0.0733 0.4987
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0019 0.0086 0.0428
Onchocerca volvulus 0.0038 0.0294 0.0892
Onchocerca volvulus 0.0078 0.0733 0.2286
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0078 0.0733 0.0723
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0078 0.0733 0.4116
Loa Loa (eye worm) serotonin transporter b 0.0073 0.0675 0.1115
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0294 0.0892
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0607 0.1001
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0019 0.0086 0.0126
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0294 0.0294
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0294 0.0294
Echinococcus granulosus g protein coupled receptor 0.0038 0.0294 0.0294
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0276 0.0445
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0294 0.0474
Plasmodium falciparum amino acid transporter, putative 0.0012 0.0013 0.0001
Onchocerca volvulus 0.0038 0.0294 0.0892
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0067 0.0607 0.1001
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0065 0.0593 0.0976
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0294 0.0474
Echinococcus granulosus sex peptide receptor 0.0038 0.0294 0.0294
Brugia malayi hypothetical protein 0.0012 0.0013 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0607 0.1001
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Brugia malayi Cation transporter family protein 0.0014 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0304 0.0492
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Trichomonas vaginalis DNA helicase recq, putative 0.0066 0.0599 0.0987
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0276 0.0445
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0019 0.0086 0.0428
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0014 0.0035 0.004
Trypanosoma cruzi hexose transporter 0.0173 0.1766 1
Onchocerca volvulus 0.0078 0.0733 0.2286
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0067 0.0608 0.0919
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0166 0.088
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0294 0.0294
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0039 0.0304 0.0304
Brugia malayi Major Facilitator Superfamily protein 0.0078 0.0733 0.1212
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0095 0.0476
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0035 0.0025
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0035 0.0025
Echinococcus granulosus solute carrier family 22 0.0078 0.0733 0.075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Echinococcus granulosus sodium and chloride dependent glycine 0.0012 0.0013 0.0001
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0294 0.0474
Schistosoma mansoni neuropeptide receptor 0.0038 0.0294 0.0474
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0035 0.0025
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0352 0.3731 0.3724
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0294 0.0474
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0014 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Trypanosoma brucei glucose transporter, putative 0.0173 0.1766 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0255 0.0409
Echinococcus multilocularis serotonin receptor 0.032 0.3379 0.3498
Brugia malayi ORL1-like opioid receptor 0.0038 0.0294 0.0474
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0294 0.0294
Echinococcus granulosus flap endonuclease 1 0.0026 0.0166 0.016
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0332 0.0539
Schistosoma mansoni amine GPCR 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0036 0.0276 0.0445
Loa Loa (eye worm) hypothetical protein 0.0036 0.0276 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0067 0.0607 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Onchocerca volvulus 0.0038 0.0294 0.0892
Plasmodium vivax calcium-dependent protein kinase, putative 0.0067 0.0608 0.0597
Mycobacterium ulcerans lipase LipD 0.0036 0.0276 0.1829
Leishmania major glucose transporter/membrane transporter D2, putative 0.0173 0.1766 1
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0019 0.0086 0.0126
Onchocerca volvulus 0.0078 0.0733 0.2286
Brugia malayi Serotonin receptor 0.0038 0.0294 0.0474
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0073 0.0675 0.1115
Brugia malayi excitatory GABA receptor EXP-1A 0.0014 0.0035 0.004
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0304 0.0492
Trichomonas vaginalis glucose transporter, putative 0.0173 0.1766 0.2946
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0019 0.0086 0.0078
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0822 0.8865 0.9196
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0035 0.004
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0014 0.0035 0.0025
Schistosoma mansoni biogenic amine receptor 0.0038 0.0294 0.0474
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.3116 0.835
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0294 0.0474
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0294 0.0294
Plasmodium falciparum flap endonuclease 1 0.0026 0.0166 0.0155
Brugia malayi hypothetical protein 0.0038 0.0294 0.0474
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0276 0.0445
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0255 0.0409
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0038 0.0044
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0294 0.0294
Toxoplasma gondii hypothetical protein 0.0012 0.0013 0.0019
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0045 0.0365 0.2017
Echinococcus multilocularis dna polymerase eta 0.0015 0.0038 0.0027
Onchocerca volvulus 0.0038 0.0294 0.0892
Trypanosoma brucei glucose transporter 2A 0.0173 0.1766 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0222 0.1199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0276 0.1097
Onchocerca volvulus 0.0038 0.0294 0.0892
Onchocerca volvulus 0.0078 0.0733 0.2286
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0013 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0294 0.0294
Echinococcus multilocularis somatostatin receptor 0.0038 0.0294 0.0294
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0332 0.2216
Entamoeba histolytica recQ family helicase, putative 0.0045 0.0365 0.0952
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0166 0.088
Echinococcus multilocularis geminin 0.0172 0.1755 0.1811
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0086 0.0428
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0294 0.0892
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0276 0.1097
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0014 0.0035 0.004
Plasmodium falciparum protein kinase 7 0.0616 0.6616 0.6612
Loa Loa (eye worm) hypothetical protein 0.0065 0.0593 0.0976
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0109 0.1068 0.1773
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0086 0.0428
Brugia malayi Sugar transporter family protein 0.0078 0.0733 0.1212
Toxoplasma gondii sugar transporter ST1 0.0078 0.0733 0.1109
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0086 0.0428
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0035 0.004
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0557 0.5968 0.6187
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0014 0.0035 0.004
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni nAChR subunit 0.0014 0.0035 0.004
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0065 0.0593 0.4014
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Brugia malayi hypothetical protein 0.0078 0.0733 0.1212
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0294 0.0294
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0039 0.0304 0.0492
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0041 0.0329 0.0318
Schistosoma mansoni DNA helicase recq5 0.0039 0.0304 0.0492
Brugia malayi hypothetical protein 0.0078 0.0733 0.1212
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0294 0.0294
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0294 0.0294
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0065 0.0593 0.0604
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0276 0.1829
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Onchocerca volvulus 0.0038 0.0294 0.0892
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0733 0.1212
Schistosoma mansoni hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0002
Trichomonas vaginalis glucose transporter, putative 0.0173 0.1766 0.2946
Onchocerca volvulus 0.0078 0.0733 0.2286
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.004
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0039 0.0304 0.0304
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0294 0.0294
Trypanosoma cruzi sugar transporter, putative 0.0078 0.0733 0.4116
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0012 0.0013 0.0002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0294 0.0474
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.3116 0.5213
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0035 0.004
Onchocerca volvulus 0.0014 0.0035 0.0071
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0166 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Onchocerca volvulus 0.0078 0.0733 0.2286
Echinococcus multilocularis sodium and chloride dependent glycine 0.0012 0.0013 0.0001
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0409 0.0669
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0019 0.0086 0.0131
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0276 0.0445
Loa Loa (eye worm) hypothetical protein 0.0032 0.0222 0.0353
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Echinococcus granulosus dna polymerase kappa 0.0042 0.0332 0.0333
Onchocerca volvulus 0.0078 0.0733 0.2286
Brugia malayi G protein-coupled receptor 0.0038 0.0294 0.0474
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0276 0.0445
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0067 0.0607 0.1001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0014 0.0035 0.004
Leishmania major DNA polymerase eta, putative 0.0015 0.0038 0.015
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0019 0.0086 0.0126
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0276 0.1097
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.013 0.0819
Mycobacterium ulcerans sugar transporter 0.0078 0.0733 0.4987
Loa Loa (eye worm) hypothetical protein 0.0109 0.1068 0.1773
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Schistosoma mansoni hypothetical protein 0.0016 0.0052 0.0068
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0019 0.0086 0.0126
Echinococcus multilocularis bloom syndrome protein 0.0066 0.0599 0.0611
Mycobacterium ulcerans integral membrane transport protein 0.0078 0.0733 0.4987
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0294 0.0294
Echinococcus granulosus GPCR family 2 0.0016 0.0052 0.0042
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.146 1
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0294 0.0474
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0067 0.0607 0.3398
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0276 0.1097
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0111 0.0566
Brugia malayi DNA polymerase family B containing protein 0.0019 0.0086 0.0126
Leishmania major glucose transporter, lmgt3 0.0173 0.1766 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0002
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0019 0.0086 0.0078
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0076 0.0711 0.3989
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0294 0.0474
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0019 0.0086 0.0234
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0294 0.0294
Trypanosoma brucei sugar transporter, putative 0.0078 0.0733 0.4116
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.043 0.0702
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0294 0.0474
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0557 0.5968 0.6187
Onchocerca volvulus 0.0078 0.0733 0.2286
Loa Loa (eye worm) hypothetical protein 0.0051 0.043 0.0702
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0014 0.0035 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0733 0.1212
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0014 0.0035 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Onchocerca volvulus 0.0038 0.0294 0.0892
Onchocerca volvulus 0.0078 0.0733 0.2286
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0276 0.1097
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0294 0.0294
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0019 0.0086 0.0428
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0002
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0015 0.0038 0.0044
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0607 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0294 0.0294
Echinococcus multilocularis serotonin transporter 0.0073 0.0675 0.069
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0332 0.1829
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0294 0.0474
Echinococcus granulosus serotonin transporter 0.0073 0.0675 0.069
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0332 0.1829
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0038 0.0044
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0012 0.0013 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0733 0.1212
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0014 0.0035 0.0025
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0052 0.0042
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0294 0.0294
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0014 0.0035 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0294 0.0474
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0014 0.0035 0.004
Brugia malayi GnHR receptor homolog 0.0038 0.0294 0.0474
Plasmodium vivax CDK-related protein kinase 6, putative 0.0926 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Loa Loa (eye worm) hypothetical protein 0.0078 0.0733 0.1212
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0019 0.0086 0.0428
Plasmodium falciparum calcium-dependent protein kinase 1 0.0067 0.0608 0.0597
Brugia malayi Sugar transporter family protein 0.0557 0.5968 1
Trichomonas vaginalis sugar transporter, putative 0.0078 0.0733 0.1212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0294 0.0474
Echinococcus multilocularis General substrate transporter 0.0479 0.5111 0.5297
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0294 0.0294
Brugia malayi major facilitator superfamily protein 0.0078 0.0733 0.1212

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 6.4 nM Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates ChEMBL. 12213056
Ki (binding) = 6.4 nM Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates ChEMBL. 12213056
Ki (binding) = 377 nM Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates ChEMBL. 12213056
Ki (binding) = 377 nM Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates ChEMBL. 12213056

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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