Detailed information for compound 269988

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 748.868 | Formula: C38H52N8O8
  • H donors: 8 H acceptors: 8 LogP: 1.34 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 3
  • SMILES: COC(=O)[C@H](NC(=O)[C@H](NC(=O)CC(C(NC(=O)[C@H](Cc1nc[nH]c1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)N)CC(C)C)O)C)Cc1ccccc1
  • InChi: 1S/C38H52N8O8/c1-23(2)15-29(32(47)19-33(48)43-24(3)35(50)46-31(38(53)54-4)17-26-13-9-6-10-14-26)45-37(52)30(18-27-20-40-22-42-27)44-34(49)21-41-36(51)28(39)16-25-11-7-5-8-12-25/h5-14,20,22-24,28-32,47H,15-19,21,39H2,1-4H3,(H,40,42)(H,41,51)(H,43,48)(H,44,49)(H,45,52)(H,46,50)/t24-,28-,29?,30-,31-,32?/m0/s1
  • InChiKey: OHFBCDFWQFKELV-PDFRUSOUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cysteine proteinase, putative 0.0028 0.0082 0.0357
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Toxoplasma gondii aspartyl protease 0.0014 0.0004 0.0006
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0023 0.0058 0.0088
Mycobacterium ulcerans hypothetical protein 0.0039 0.0146 0.1808
Brugia malayi Sugar transporter family protein 0.0059 0.0258 0.0367
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0079 0.0328
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0034 0.0343
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0369 0.4377
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0047 0.0072
Echinococcus multilocularis cysteine protease 0.0054 0.023 0.0252
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0023 0.0058 0.0315
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.0198
Schistosoma mansoni glucose transport protein 0.0418 0.2298 0.3274
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0045 0.005
Schistosoma mansoni tyrosine kinase 0.039 0.2139 0.3048
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0085 0.0405 0.2849
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0205 0.0225
Echinococcus multilocularis Mastin 0.0018 0.0029 0.0031
Plasmodium falciparum protease, putative 0.0039 0.0146 0.0146
Onchocerca volvulus Putative transporter 0.0059 0.0258 0.1816
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0369 0.0557
Onchocerca volvulus 0.0036 0.0129 0.0902
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.1675 0.2386
Echinococcus granulosus intermediate filament protein 0.0112 0.056 0.0798
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Echinococcus multilocularis lamin 0.0112 0.056 0.0614
Loa Loa (eye worm) hypoxia-induced factor 1 0.0324 0.1766 0.2515
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0129 0.1288
Onchocerca volvulus 0.0059 0.0258 0.1816
Loa Loa (eye worm) glutamate receptor 1 0.0121 0.0611 0.0869
Toxoplasma gondii anticodon binding domain-containing protein 0.0014 0.0005 0.0007
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Brugia malayi Calcitonin receptor-like protein seb-1 0.0156 0.0812 0.1157
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Echinococcus multilocularis solute carrier family 22 0.0059 0.0258 0.0283
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0027 0.0079 0.0328
Trypanosoma brucei C-8 sterol isomerase, putative 0.0415 0.2285 1
Schistosoma mansoni tyrosine kinase 0.1248 0.7017 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0043 0.0186
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0147 0.0147
Plasmodium falciparum plasmepsin III 0.0014 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0308 0.1675 0.2387
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0047 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0185 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Echinococcus granulosus glutamate receptor subunit protein glur 0.0045 0.0178 0.0254
Onchocerca volvulus 0.0059 0.0258 0.1816
Loa Loa (eye worm) major facilitator superfamily transporter 0.0059 0.0258 0.0367
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0152 0.0789 1
Toxoplasma gondii sugar transporter ST2 0.0059 0.0258 0.0389
Onchocerca volvulus 0.0054 0.023 0.1613
Brugia malayi Trypsin family protein 0.0018 0.0029 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0258 0.1109
Loa Loa (eye worm) hypothetical protein 0.0085 0.0405 0.0576
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0135 0.057
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0021 0.0091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0082 0.0115
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0014 0.0004 0.0003
Echinococcus granulosus epidermal growth factor receptor 0.1248 0.7017 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0079 0.0328
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0082 0.0817
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Echinococcus granulosus cathepsin L cysteine proteinase 0.0054 0.023 0.0327
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.03 0.0329
Leishmania major protein kinase, putative 0.0128 0.0654 0.2862
Leishmania major lysyl-tRNA synthetase, putative 0.0093 0.0454 0.1988
Toxoplasma gondii aspartyl protease ASP1 0.0014 0.0004 0.0006
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Onchocerca volvulus 0.0018 0.0029 0.0196
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0286 0.0313
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0059 0.0258 0.0283
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0128 0.0654 0.2862
Brugia malayi bHLH-PAS transcription factor 0.0077 0.0365 0.0519
Mycobacterium ulcerans putative regulatory protein 0.0077 0.0365 0.4593
Leishmania major histidyl-tRNA synthetase, putative 0.0014 0.0005 0.0021
Echinococcus multilocularis glycoprotein Antigen 5 0.0018 0.0029 0.0031
Schistosoma mansoni lipoxygenase 0.0353 0.1933 0.2754
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0047 0.0068
Onchocerca volvulus 0.0027 0.0079 0.0552
Entamoeba histolytica protein kinase, putative 0.0128 0.0654 0.6544
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0079 0.0346
Chlamydia trachomatis threonine--tRNA ligase 0.0023 0.0058 0.1193
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0054 0.023 0.0252
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0418 0.2298 0.2519
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0129 0.066 0.094
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0021 0.003
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0082 0.0817
Trichomonas vaginalis sugar transporter, putative 0.013 0.0661 0.2863
Plasmodium falciparum proline--tRNA ligase 0.0146 0.0755 0.0755
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0036 0.0127 0.0556
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0717
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0295 0.0419
Toxoplasma gondii sugar transporter ST1 0.0059 0.0258 0.0389
Loa Loa (eye worm) hypothetical protein 0.0156 0.0812 0.1157
Schistosoma mansoni lamin 0.0112 0.056 0.0798
Trichomonas vaginalis glucose transporter, putative 0.013 0.0661 0.2863
Schistosoma mansoni ran 0.0021 0.0045 0.0064
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0369 0.0526
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0014 0.0005 0.0004
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0045 0.0178 0.0196
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0231 0.033
Brugia malayi hypothetical protein 0.0059 0.0258 0.0367
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0034 0.0381
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.026 0.1137
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0045
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0109 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0021 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0 0.0001
Brugia malayi isocitrate dehydrogenase 0.0032 0.0109 0.0154
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0034 0.0038
Onchocerca volvulus 0.0059 0.0258 0.1816
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Echinococcus multilocularis snurportin 1 0.0308 0.1675 0.1837
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0043 0.0169
Brugia malayi Inositol-1 0.0037 0.0135 0.0191
Echinococcus granulosus receptor type guanylyl cyclase 0.0013 0.0001 0.0001
Entamoeba histolytica CAAX amino terminal protease family 0.0039 0.0146 0.1464
Brugia malayi RNA, U transporter 1 0.0082 0.0391 0.0556
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0093 0.0454 0.0646
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0854 0.4776 0.6806
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0125 0.0637 0.7957
Brugia malayi Cathepsin L-like precursor 0.0036 0.0129 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0 0.0001
Schistosoma mansoni protein kinase 0.0128 0.0654 0.0932
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0128 0.0654 0.0931
Brugia malayi Major Facilitator Superfamily protein 0.0059 0.0258 0.0367
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Echinococcus granulosus nmda type glutamate receptor 0.0134 0.0684 0.0975
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0093 0.0454 0.1964
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0034 0.015
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0135 0.0203
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0022 0.0047 0.0066
Mycobacterium ulcerans hypothetical protein 0.0152 0.0789 1
Schistosoma mansoni sugar transporter 0.0059 0.0258 0.0368
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0089 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0 0.0001
Echinococcus multilocularis cysteine protease 0.0054 0.023 0.0252
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0082 0.0817
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0023 0.0058 0.0254
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0183 0.0965 0.1057
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.026 0.1137
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0717
Loa Loa (eye worm) hypothetical protein 0.0109 0.0545 0.0776
Trypanosoma brucei THT1 - hexose transporter, putative 0.013 0.0661 0.2891
Echinococcus granulosus dna polymerase kappa 0.0019 0.0034 0.0049
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0014 0.0004 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Echinococcus granulosus cathepsin l1 0.0054 0.023 0.0327
Plasmodium falciparum mitogen-activated protein kinase 2 0.0675 0.3762 0.3762
Loa Loa (eye worm) hypothetical protein 0.0017 0.0021 0.0029
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0059 0.0258 0.3235
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0333 0.0365
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0286 0.0407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Trypanosoma brucei glucose transporter 2A 0.013 0.0661 0.2891
Echinococcus multilocularis Polycystic kidney disease protein 0.0085 0.0405 0.0444
Brugia malayi Trypsin family protein 0.0109 0.0545 0.0776
Loa Loa (eye worm) hypothetical protein 0.0054 0.023 0.0326
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Plasmodium vivax asparagine--tRNA ligase, putative 0.0014 0.0004 0.0001
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0027 0.0079 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0035
Echinococcus granulosus calcium dependent protein kinase 0.012 0.0606 0.0864
Echinococcus multilocularis solute carrier family 22 0.0059 0.0258 0.0283
Entamoeba histolytica Ran family GTPase 0.0021 0.0045 0.0453
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0079 0.0346
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Trypanosoma brucei glucose transporter 1E 0.013 0.0661 0.2891
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0018 0.0025 0.0035
Plasmodium vivax vivapain-1 0.0028 0.0082 0.0078
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.026 0.1137
Brugia malayi hypothetical protein 0.0072 0.0333 0.0473
Loa Loa (eye worm) hypothetical protein 0.011 0.0549 0.0781
Schistosoma mansoni microtubule-associated protein tau 0.0691 0.3849 0.5485
Schistosoma mansoni tyrosine kinase 0.0849 0.4749 0.6767
Trypanosoma brucei unspecified product 0.0019 0.0034 0.015
Brugia malayi jmjC domain containing protein 0.0064 0.0286 0.0406
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.03 0.0427
Entamoeba histolytica hypothetical protein 0.0072 0.0333 0.3329
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.026 0.0285
Echinococcus granulosus insulin growth factor 1 receptor beta 0.039 0.2139 0.3048
Echinococcus granulosus aryl hydrocarbon receptor 0.0027 0.0079 0.0113
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.03 0.0426
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0063
Echinococcus granulosus CAAX prenyl protease 2 0.0189 0.0999 0.1424
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.004
Entamoeba histolytica cysteine protease, putative 0.0054 0.023 0.2297
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0054 0.023 0.023
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0023 0.0058 0.0064
Plasmodium falciparum ornithine aminotransferase 0.0022 0.0047 0.0047
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0021 0.003
Brugia malayi hypothetical protein 0.0085 0.0405 0.0576
Onchocerca volvulus 0.0059 0.0258 0.1816
Echinococcus multilocularis General substrate transporter 0.0359 0.1964 0.2153
Schistosoma mansoni rab6-interacting 0.0085 0.0405 0.0577
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0088 0.0124
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0078 0.2011
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Toxoplasma gondii protein kinase, putative 0.118 0.6633 1
Schistosoma mansoni tyrosine kinase 0.0849 0.4749 0.6767
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0418 0.2298 0.3274
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0654 0.2834
Toxoplasma gondii facilitative glucose transporter GT1 0.0418 0.2298 0.3464
Brugia malayi Major Facilitator Superfamily protein 0.0059 0.0258 0.0367
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.003 0.0043
Trypanosoma brucei unspecified product 0.0013 0 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.0959 0.5372 0.5889
Loa Loa (eye worm) hypothetical protein 0.0036 0.0129 0.0182
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0079 0.0374 0.4446
Onchocerca volvulus 0.0059 0.0258 0.1816
Schistosoma mansoni glutamate receptor kainate 0.0121 0.0611 0.087
Plasmodium falciparum cysteine proteinase falcipain 3 0.0054 0.023 0.023
Onchocerca volvulus 0.0059 0.0258 0.1816
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0034 0.015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0135 0.0589
Brugia malayi hypothetical protein 0.0237 0.1269 0.1808
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0146 0.1484
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0034 0.0049
Echinococcus multilocularis nmda type glutamate receptor 0.0098 0.0479 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0135 0.057
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.003 0.0033
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0014 0.0005 0.0004
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0113 0.1037
Brugia malayi hypothetical protein 0.0059 0.0258 0.0367
Leishmania major hypothetical protein, conserved 0.0021 0.0043 0.0186
Echinococcus granulosus cysteine protease 0.0028 0.0082 0.0116
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.023 0.2297
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.03 0.1313
Trichomonas vaginalis conserved hypothetical protein 0.0418 0.2298 1
Schistosoma mansoni rab6-interacting 0.0085 0.0405 0.0577
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0082 0.0357
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0059 0.0258 0.2967
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0135 0.0148
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.01 0.0142
Loa Loa (eye worm) hypothetical protein 0.0189 0.0999 0.1423
Loa Loa (eye worm) hypothetical protein 0.0163 0.0852 0.1214
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Onchocerca volvulus 0.0018 0.0029 0.0196
Brugia malayi jmjC domain containing protein 0.0065 0.0295 0.0419
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0048
Brugia malayi Cathepsin L-like precursor 0.0054 0.023 0.0326
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.0265 0.0377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Trypanosoma cruzi cysteine proteinase, putative 0.0028 0.0082 0.0357
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0044
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0152 0.0789 1
Trypanosoma brucei CAAX amino terminal protease, putative 0.0189 0.0999 0.4373
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0135 0.057
Onchocerca volvulus 0.0059 0.0258 0.1816
Schistosoma mansoni cpg binding protein 0.0029 0.0088 0.0125
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0418 0.2298 0.3274
Onchocerca volvulus 0.0163 0.0852 0.6005
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0135 0.1659
Onchocerca volvulus 0.0018 0.0029 0.0196
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0128 0.0654 0.0987
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0004 0.0006
Loa Loa (eye worm) glutamate receptor 2 0.0121 0.0611 0.0869
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Echinococcus granulosus geminin 0.017 0.0888 0.1266
Trypanosoma cruzi cruzipain precursor, putative 0.0018 0.0025 0.0111
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0058 0.0234
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0216 0.2408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0932
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0014 0.0004 0.0005
Plasmodium falciparum plasmepsin IX 0.0112 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0082
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0043 0.0169
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0041
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Echinococcus granulosus single minded 2 0.0077 0.0365 0.052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0112
Plasmodium vivax vivapain-2 0.0054 0.023 0.0226
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.03 0.3002
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0044 0.0176 0.2187
Entamoeba histolytica CAAX prenyl protease family 0.0189 0.0999 1
Onchocerca volvulus 0.0059 0.0258 0.1816
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.011 0.0157
Schistosoma mansoni tyrosine kinase 0.0013 0.0001 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0109 0.0119
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.026 0.0369
Plasmodium falciparum plasmepsin VII 0.0014 0.0004 0.0004
Plasmodium vivax calcium-dependent protein kinase, putative 0.0128 0.0654 0.0651
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0059 0.0258 0.3235
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Leishmania major protein kinase, putative 0.0036 0.0127 0.0556
Schistosoma mansoni polycystin 1-related 0.0085 0.0405 0.0577
Onchocerca volvulus 0.0014 0.0004 0.0021
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0021 0.0029
Schistosoma mansoni hypothetical protein 0.017 0.0888 0.1266
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0109 0.0477
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0078 0.0369 0.0525
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0135 0.1347
Brugia malayi hypothetical protein 0.0163 0.0852 0.1214
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Echinococcus granulosus tyrosine kinase 0.0013 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Schistosoma mansoni glucose transport protein 0.0418 0.2298 0.3274
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0146 0.0755 0.3302
Echinococcus multilocularis aryl hydrocarbon receptor 0.0027 0.0079 0.0087
Loa Loa (eye worm) hypothetical protein 0.0112 0.056 0.0797
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0047 0.0068
Loa Loa (eye worm) ctsf protein 0.0054 0.023 0.0326
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0128 0.0654 0.0932
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0054 0.023 0.0984
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0034 0.0049
Onchocerca volvulus 0.0255 0.1371 0.9666
Loa Loa (eye worm) trypsin family protein 0.0018 0.0029 0.004
Echinococcus granulosus RUN 0.0085 0.0405 0.0577
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0014 0.0004 0.0006
Onchocerca volvulus 0.0085 0.0405 0.2849
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0185 0.0202
Onchocerca volvulus Cathepsin F homolog 0.0054 0.023 0.1613
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0039 0.0146 0.1484
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0027 0.0079 0.0328
Plasmodium falciparum threonine--tRNA ligase 0.0023 0.0058 0.0058
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0082 0.0817
Brugia malayi Trypsin-like protease protein 5 0.0018 0.0029 0.004
Echinococcus multilocularis cathepsin L cysteine protease 0.0054 0.023 0.0252
Echinococcus multilocularis dna polymerase eta 0.0019 0.0034 0.0038
Schistosoma mansoni lamin 0.0112 0.056 0.0798
Schistosoma mansoni cathepsin D (A01 family) 0.0129 0.0657 0.0936
Giardia lamblia Glycyl-tRNA synthetase 0.0023 0.0058 0.054
Brugia malayi Sugar transporter family protein 0.0059 0.0258 0.0367
Plasmodium vivax aspartate--tRNA ligase, putative 0.0014 0.0004 0.0001
Onchocerca volvulus 0.0059 0.0258 0.1816
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0059 0.0258 0.0368
Entamoeba histolytica CAAX amino terminal protease family 0.0039 0.0146 0.1464
Schistosoma mansoni hypothetical protein 0.0045 0.0178 0.0254
Plasmodium vivax glycine--tRNA ligase, putative 0.0023 0.0058 0.0054
Plasmodium falciparum importin beta, putative 0.0029 0.0089 0.0089
Schistosoma mansoni intermediate filament proteins 0.0112 0.056 0.0798
Plasmodium vivax JmjC domain containing protein 0.0017 0.0021 0.0017
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0027 0.0079 0.0112
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.011 0.0121
Echinococcus multilocularis tumor protein p63 0.0338 0.1846 0.2024
Trichomonas vaginalis adenylate cyclase, putative 0.0027 0.0079 0.0328
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma cruzi hexose transporter, putative 0.0059 0.0258 0.113
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0014 0.0004 0.0044
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0135 0.0589
Brugia malayi Cathepsin L-like precursor 0.0054 0.023 0.0326
Echinococcus multilocularis cathepsin L cysteine protease 0.0054 0.023 0.0252
Onchocerca volvulus 0.0054 0.023 0.1613
Giardia lamblia Sugar-proton symporter 0.0059 0.0258 0.2552
Echinococcus granulosus transmembrane protease serine 3 0.0018 0.0029 0.0041
Plasmodium vivax asparagine--tRNA ligase, putative 0.0014 0.0004 0.0001
Echinococcus granulosus Aminotransferase class III 0.0022 0.0047 0.0068
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0932
Schistosoma mansoni tyrosine kinase 0.0849 0.4749 0.6767
Brugia malayi Trypsin family protein 0.0018 0.0029 0.004
Onchocerca volvulus 0.0048 0.0199 0.1397
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Schistosoma mansoni glutamate receptor NMDA 0.0183 0.0965 0.1375
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.026 0.1137
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0034 0.015
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0129 0.066 0.094
Trypanosoma brucei protein kinase, putative 0.0059 0.026 0.1137
Brugia malayi PAS domain containing protein 0.0105 0.0519 0.0739
Echinococcus multilocularis solute carrier family 22 0.0059 0.0258 0.0283
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0109 0.0545 0.0777
Schistosoma mansoni tyrosine kinase 0.039 0.2139 0.3048
Plasmodium vivax ornithine aminotransferase, putative 0.0022 0.0047 0.0044
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Echinococcus multilocularis lipoxygenase domain containing protein 0.0085 0.0405 0.0444
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.026 0.037
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0047 0.0957
Onchocerca volvulus 0.0054 0.023 0.1613
Giardia lamblia Prolyl-tRNA synthetase 0.0125 0.0637 0.6355
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.026 0.037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0035
Plasmodium vivax threonine--tRNA ligase, putative 0.0023 0.0058 0.0054
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0079 0.0328
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0675 0.3762 0.376
Plasmodium falciparum plasmepsin I 0.0014 0.0004 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0156 0.0812 0.1157
Echinococcus multilocularis 0.066 0.3673 0.4026
Schistosoma mansoni tyrosine kinase 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0054 0.0231 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0237 0.1269 0.1808
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0199 0.0282
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0023 0.0058 0.1471
Trypanosoma brucei THT1 - hexose transporter, putative 0.013 0.0661 0.2891
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0079 0.0346
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0109 0.0164
Leishmania major cathepsin L-like protease 0.0054 0.023 0.1005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0286 0.0313
Brugia malayi Protein kinase domain containing protein 0.039 0.2139 0.3048
Loa Loa (eye worm) hypothetical protein 0.0263 0.1419 0.2021
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0021 0.003
Plasmodium vivax protease, putative 0.0039 0.0146 0.0143
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0093 0.0454 0.5733
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Echinococcus granulosus glutamate receptor 2 0.0085 0.0406 0.0578
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0369 0.0526
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0034 0.0133
Plasmodium falciparum calcium-dependent protein kinase 4 0.0128 0.0654 0.0654
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0014 0.0004 0.0006
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0749 0.0821
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0167 0.0711
Leishmania major DNA polymerase eta, putative 0.0019 0.0034 0.015
Entamoeba histolytica protein kinase, putative 0.0128 0.0654 0.6544
Loa Loa (eye worm) TK/EGFR protein kinase 0.1248 0.7017 1
Echinococcus granulosus neuropeptide receptor A26 0.0959 0.5372 0.7655
Giardia lamblia DINP protein human, muc B family 0.0019 0.0034 0.0301
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0185 0.0263
Echinococcus multilocularis transfer RNA-Lys 0.0077 0.0365 0.04
Onchocerca volvulus 0.0018 0.0029 0.0196
Schistosoma mansoni survival motor neuron protein 0.0048 0.0199 0.0283
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.026 0.1116
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0216 0.0237
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.03 0.1313
Echinococcus multilocularis glycyl tRNA synthetase 0.0023 0.0058 0.0064
Leishmania major importin beta-1 subunit, putative 0.0023 0.0058 0.0252
Onchocerca volvulus 0.0059 0.0258 0.1816
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0021 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0036 0.0127 0.0556
Leishmania major cathepsin L-like protease 0.0204 0.1087 0.4755
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0043 0.0186
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0036 0.0127 0.0556
Schistosoma mansoni histidyl-tRNA synthetase 0.0014 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0258 0.1109
Loa Loa (eye worm) hypothetical protein 0.0029 0.0089 0.0125
Brugia malayi Cam kinase protein 1 0.0128 0.0654 0.0931
Schistosoma mansoni lipoxygenase 0.0505 0.2797 0.3986
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.015
Loa Loa (eye worm) hypothetical protein 0.0052 0.022 0.0312
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0018 0.0029 0.0041
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0014 0.0005 0.0021
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.03 0.0426
Toxoplasma gondii cathepsin CPL 0.0054 0.023 0.0346
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Echinococcus granulosus microtubule associated protein 2 0.0691 0.3849 0.5485
Loa Loa (eye worm) hypothetical protein 0.0351 0.192 0.2736
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0029 0.0041
Toxoplasma gondii sugar transporter ST3 0.0059 0.0258 0.0389
Brugia malayi Probable ClpP-like protease 0.0078 0.0369 0.0525
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0152 0.0789 0.3423
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0047 0.0549
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0045 0.0064
Echinococcus granulosus lysyl tRNA synthetase 0.0093 0.0454 0.0647
Toxoplasma gondii transporter, major facilitator family protein 0.0059 0.0258 0.0389
Loa Loa (eye worm) TK/INSR protein kinase 0.039 0.2139 0.3048
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.023 0.2297
Schistosoma mansoni importin beta-1 0.0029 0.0089 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Leishmania major cathepsin L-like protease 0.0054 0.023 0.1005
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0147 0.1431
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0041
Loa Loa (eye worm) hypothetical protein 0.0052 0.022 0.0312
Echinococcus multilocularis epidermal growth factor receptor 0.1248 0.7017 0.7693
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0205 0.0292
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0058 0.0252
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.011 0.0121
Plasmodium falciparum plasmepsin II 0.0014 0.0004 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0185 0.0262
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0043 0.0186
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0125 0.0637 0.6371
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Plasmodium vivax aspartyl protease, putative 0.0112 0.0564 0.056
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0109 0.0477
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0189 0.0999 0.1424
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0418 0.2298 0.2519
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0078 0.0074
Brugia malayi Cathepsin L-like precursor 0.0054 0.023 0.0326
Schistosoma mansoni aryl hydrocarbon receptor 0.0105 0.0519 0.074
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0034 0.0133
Brugia malayi Importin beta-1 subunit 0.0029 0.0089 0.0125
Echinococcus multilocularis transmembrane protease serine 3 0.0018 0.0029 0.0031
Loa Loa (eye worm) acetyltransferase 0.0145 0.0749 0.1066
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0113 0.0939
Brugia malayi major facilitator superfamily protein 0.0059 0.0258 0.0367
Leishmania major glycyl tRNA synthetase, putative 0.0014 0.0005 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0082 0.0115
Echinococcus granulosus glutamate receptor 2 0.0129 0.066 0.094
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Onchocerca volvulus 0.0059 0.0258 0.1816
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0147 0.1469
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0167 0.0238
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0125 0.0637 0.0907
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0078 0.0078
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0749 0.1067
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Echinococcus granulosus snurportin 1 0.0308 0.1675 0.2387
Leishmania major myo-inositol/proton symporter (MIT) 0.0059 0.0258 0.113
Schistosoma mansoni sugar transporter 0.0059 0.0258 0.0368
Schistosoma mansoni hypothetical protein 0.0409 0.2251 0.3208
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0418 0.2298 0.2519
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1619 0.9122 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0128 0.0654 0.0654
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Schistosoma mansoni hypothetical protein 0.0085 0.0405 0.0577
Schistosoma mansoni ran 0.0021 0.0045 0.0064
Echinococcus multilocularis calcium dependent protein kinase 0.012 0.0606 0.0665
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0129 0.066 0.094
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0034 0.015
Brugia malayi Cathepsin L-like cysteine proteinase 0.0036 0.0129 0.0182
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0023 0.0058 0.0254
Schistosoma mansoni hypothetical protein 0.0049 0.0205 0.0293
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0034 0.0049
Echinococcus multilocularis glutamate receptor NMDA 0.0089 0.043 0.0472
Leishmania major threonyl-tRNA synthetase, putative 0.0023 0.0058 0.0254
Trichomonas vaginalis ran, putative 0.0021 0.0045 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma cruzi cysteine peptidase, putative 0.0204 0.1087 0.4755
Schistosoma mansoni inositol monophosphatase 0.0037 0.0135 0.0192
Loa Loa (eye worm) hypothetical protein 0.0049 0.0205 0.0292
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0185 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.026 0.1116
Echinococcus granulosus importin subunit beta 1 0.0029 0.0089 0.0126
Plasmodium vivax vivapain-3 0.0028 0.0082 0.0078
Trypanosoma brucei THT1 - hexose transporter, putative 0.013 0.0661 0.2891
Plasmodium vivax vivapain-2 0.0054 0.023 0.0226
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0167 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0029 0.0041
Brugia malayi intermediate filament protein 0.0112 0.056 0.0797
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0014 0.0004 0.0005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0129 0.066 0.0723
Schistosoma mansoni protein kinase 0.0128 0.0654 0.0932
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0146 0.0755 0.3302
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Mycobacterium ulcerans hypothetical protein 0.0039 0.0146 0.1808
Schistosoma mansoni ATP-binding cassette transporter 0.0121 0.0611 0.087
Loa Loa (eye worm) cysteine protease 0.0054 0.023 0.0326
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0089 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Echinococcus multilocularis cpg binding protein 0.003 0.0097 0.0107
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Mycobacterium ulcerans sugar transporter 0.0059 0.0258 0.3235
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0047 0.0174
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0014 0.0005 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0082 0.0357
Plasmodium vivax SET domain protein, putative 0.0033 0.011 0.0106
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0078 0.0472
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0109 0.0154
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0059 0.0258 0.0258
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0014 0.0004 0.0004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0109 0.0477
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0034 0.015
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 1
Onchocerca volvulus Huntingtin homolog 0.0263 0.1419 1
Brugia malayi MH2 domain containing protein 0.0119 0.0604 0.0859
Trypanosoma cruzi cysteine protease, putative 0.0028 0.0082 0.0357
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.011 0.0157
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0034 0.0381
Schistosoma mansoni glutamate receptor AMPA 0.0121 0.0611 0.087
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0415 0.2285 0.3256
Onchocerca volvulus 0.0059 0.0258 0.1816
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0034 0.0048
Trichomonas vaginalis sugar transport protein, putative 0.0059 0.0258 0.1109
Echinococcus multilocularis GPCR, family 2 0.0049 0.0205 0.0225
Echinococcus granulosus lamin dm0 0.0112 0.056 0.0798
Entamoeba histolytica cysteine proteinase 2 0.0028 0.0082 0.0817
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0045 0.0178 0.0254
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0028 0.0082 0.0116
Schistosoma mansoni threonyl-tRNA synthetase 0.0014 0.0005 0.0007
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0187 0.0986 0.4314
Toxoplasma gondii CAAX amino terminal protease family protein 0.0039 0.0146 0.0221
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0079 0.0328
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0021 0.0021
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0125 0.0637 0.0907
Schistosoma mansoni cathepsin D (A01 family) 0.0129 0.0657 0.0936
Brugia malayi Glutamate receptor 2 precursor 0.0121 0.0611 0.0869
Echinococcus multilocularis nmda type glutamate receptor 0.0134 0.0684 0.075
Onchocerca volvulus 0.0077 0.0365 0.2567
Leishmania major glucose transporter, lmgt2 0.013 0.0661 0.2891
Brugia malayi Sugar transporter family protein 0.0418 0.2298 0.3274
Brugia malayi Intermediate filament tail domain containing protein 0.0112 0.056 0.0797
Leishmania major cathepsin L-like protease 0.0054 0.023 0.1005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.004
Giardia lamblia Hypothetical protein 0.0189 0.0999 1
Trypanosoma cruzi sugar transporter, putative 0.0059 0.0258 0.113
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.023 0.0326
Brugia malayi Cathepsin L-like precursor 0.0018 0.0025 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.015
Echinococcus multilocularis NMDA receptor 0.0045 0.0178 0.0196
Loa Loa (eye worm) hypothetical protein 0.0017 0.0021 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Onchocerca volvulus 0.0054 0.023 0.1613
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0185 0.0263
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0261 0.0393
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma cruzi hexose transporter, putative 0.013 0.0661 0.2891
Entamoeba histolytica hypothetical protein 0.0072 0.0333 0.3329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0128 0.0654 0.0987
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0021 0.0031
Schistosoma mansoni cathepsin F (C01 family) 0.0054 0.023 0.0327
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0045 0.0178 0.0196
Loa Loa (eye worm) doublecortin family protein 0.0085 0.0405 0.0576
Schistosoma mansoni cpg binding protein 0.003 0.0097 0.0139
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.026 0.2567
Trypanosoma cruzi hexose transporter, putative 0.0071 0.0327 0.143
Brugia malayi CXXC zinc finger family protein 0.0029 0.0088 0.0124
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0411
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0021 0.0043 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0047 0.0549
Onchocerca volvulus 0.0018 0.0029 0.0196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0185 0.0263
Trypanosoma brucei histidyl-tRNA synthetase 0.0014 0.0005 0.0021
Chlamydia trachomatis proline--tRNA ligase 0.0044 0.0176 0.3815
Trichomonas vaginalis set domain proteins, putative 0.0255 0.1371 0.5961
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0085 0.0405 0.0444
Trichomonas vaginalis sugar transporter, putative 0.013 0.0661 0.2863
Loa Loa (eye worm) hypothetical protein 0.0102 0.0503 0.0716
Echinococcus granulosus neuropeptide s receptor 0.0959 0.5372 0.7655
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Schistosoma mansoni inositol monophosphatase 0.0037 0.0135 0.0192
Brugia malayi jmjC domain containing protein 0.0017 0.0021 0.0029
Schistosoma mansoni hypothetical protein 0.017 0.0888 0.1266
Echinococcus granulosus nmda type glutamate receptor 0.0098 0.0479 0.0683
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0021 0.0031
Brugia malayi Cathepsin L-like precursor 0.0054 0.023 0.0326
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 0.465
Schistosoma mansoni hypothetical protein 0.0049 0.0205 0.0293
Trypanosoma cruzi hexose transporter, putative 0.013 0.0661 0.2891
Leishmania major DNA polymerase kappa, putative 0.0019 0.0034 0.015
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0029 0.0041
Echinococcus granulosus cathepsin L cysteine protease 0.0028 0.0082 0.0116
Trypanosoma cruzi hexose transporter, putative 0.013 0.0661 0.2891
Schistosoma mansoni histidyl-tRNA synthetase 0.0014 0.0005 0.0007
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0333 0.0474
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Echinococcus granulosus glutamate receptor NMDA 0.0089 0.043 0.0613
Plasmodium falciparum plasmepsin VIII, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0058 0.0234
Mycobacterium tuberculosis Probable integral membrane protein 0.0039 0.0146 0.1484
Onchocerca volvulus 0.0054 0.023 0.1613
Leishmania major glucose transporter, lmgt3 0.013 0.0661 0.2891
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0054 0.023 0.0326
Loa Loa (eye worm) hypothetical protein 0.005 0.0206 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0654 0.0932
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.026 0.1137
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0089 0.0133
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0014 0.0005 0.0021
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0128 0.0654 0.0651
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0129 0.0183
Toxoplasma gondii hypothetical protein 0.0039 0.0146 0.0221
Plasmodium falciparum plasmepsin V 0.0014 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0049 0.0205 0.0293
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0135 0.3568
Schistosoma mansoni cathepsin F (C01 family) 0.0054 0.023 0.0327
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.1269 0.1392
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.0107 0.0531 0.0756
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0022 0.0047 0.0066
Echinococcus granulosus cathepsin l1 0.0036 0.0129 0.0183
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0205 0.0293
Echinococcus granulosus phd:f box containing protein 0.0017 0.0021 0.003
Echinococcus multilocularis lamin dm0 0.0112 0.056 0.0614
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Loa Loa (eye worm) sugar transporter 0.0059 0.0258 0.0367
Echinococcus multilocularis cathepsin L 0.0028 0.0082 0.009
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0369 0.0557
Entamoeba histolytica cysteine proteinase 1, putative 0.0028 0.0082 0.0817
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.015
Plasmodium vivax importin-beta 2, putative 0.0029 0.0089 0.0085
Schistosoma mansoni hypothetical protein 0.0048 0.0199 0.0283
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0043 0.0169
Echinococcus multilocularis RUN 0.0085 0.0405 0.0444
Loa Loa (eye worm) hypothetical protein 0.0125 0.0637 0.0906
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0021 0.003
Echinococcus granulosus solute carrier family 22 0.0059 0.0258 0.0368
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0604 0.0859
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 1
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0125 0.0637 0.2758
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Echinococcus granulosus glycyl tRNA synthetase 0.0023 0.0058 0.0083
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0058 0.0234
Echinococcus granulosus synaptic vesicle 2 protein 0.0059 0.0258 0.0368
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0109 0.0154
Echinococcus multilocularis neuropeptide s receptor 0.0959 0.5372 0.5889
Plasmodium vivax CDK-related protein kinase 6, putative 0.1773 1 1
Trichomonas vaginalis glucose transporter, putative 0.0059 0.0258 0.1109
Onchocerca volvulus 0.0033 0.011 0.077
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0295 0.042
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Brugia malayi Pepsin A precursor 0.0014 0.0004 0.0004
Plasmodium falciparum calcium-dependent protein kinase 1 0.0128 0.0654 0.0654
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.1196 0.1704
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0059 0.0258 0.113
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 0.8111
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0023 0.0058 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0128 0.0654 0.0651
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0079 0.0328
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0109 0.0988
Brugia malayi Eukaryotic aspartyl protease family protein 0.0014 0.0004 0.0004
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0047 0.0549
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Onchocerca volvulus 0.0029 0.0088 0.0614
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Brugia malayi hypothetical protein 0.0263 0.1419 0.2021
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0205 0.0292
Onchocerca volvulus 0.0014 0.0004 0.0021
Chlamydia trachomatis histidine--tRNA ligase 0.0014 0.0005 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0204 0.1087 0.4755
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0014 0.0004 0.0016
Brugia malayi hypothetical protein 0.0018 0.0029 0.004
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0027 0.0079 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Giardia lamblia Threonyl-tRNA synthetase 0.0023 0.0058 0.054
Schistosoma mansoni cathepsin s 0.0018 0.0025 0.0036
Brugia malayi Aspartyl-tRNA synthetase 0.0014 0.0004 0.0005
Mycobacterium leprae Possible regulatory protein 0.0027 0.0079 0.0491
Echinococcus multilocularis musashi 0.0112 0.056 0.0614
Plasmodium falciparum asparagine--tRNA ligase 0.0014 0.0004 0.0004
Echinococcus granulosus lipoxygenase domain containing protein 0.0085 0.0405 0.0577
Entamoeba histolytica hypothetical protein 0.0072 0.0333 0.3329
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0054 0.023 0.0252
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0021 0.003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0135 0.0589
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0189 0.0999 0.4339
Trypanosoma cruzi cruzipain precursor, putative 0.0204 0.1087 0.4755
Onchocerca volvulus 0.0059 0.0258 0.1816
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Echinococcus granulosus histidyl tRNA synthetase 0.0014 0.0005 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0185 0.0263
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0022 0.0047 0.0066
Schistosoma mansoni glutamate receptor kainate 0.0121 0.0611 0.087
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0018 0.0029 0.0041
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.0198
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0023 0.0058 0.0581
Schistosoma mansoni protein kinase 0.0013 0.0001 0.0001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0021 0.0091
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0152 0.0789 1
Schistosoma mansoni tyrosine kinase 0.0854 0.4776 0.6806
Echinococcus granulosus dna polymerase eta 0.0019 0.0034 0.0049
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0128 0.0654 0.0931
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.0265 0.0377
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0146 0.0755 0.1138
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0045 0.0178 0.0254
Loa Loa (eye worm) hypothetical protein 0.0109 0.0545 0.0776
Treponema pallidum prolyl-tRNA synthetase 0.0044 0.0176 0.4704
Schistosoma mansoni tyrosine kinase 0.0854 0.4776 0.6806
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0079 0.0328
Brugia malayi MAP kinase sur-1 0.0059 0.026 0.0369
Echinococcus granulosus Sugar transporter ERD6 protein 0.0059 0.0258 0.0368
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0089 0.0387
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Plasmodium falciparum calcium-dependent protein kinase 5 0.0128 0.0654 0.0654
Entamoeba histolytica hypothetical protein 0.0093 0.0454 0.4547
Plasmodium vivax lysine--tRNA ligase, putative 0.0093 0.0454 0.0451
Echinococcus granulosus General substrate transporter 0.0359 0.1964 0.2799
Loa Loa (eye worm) hypothetical protein 0.0085 0.0405 0.0576
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0112 0.056 0.0797
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0167 0.0711
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 0.8111
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0054 0.023 0.023
Giardia lamblia Hexose transporter 0.0059 0.0258 0.2552
Trichomonas vaginalis glucose transporter, putative 0.013 0.0661 0.2863
Onchocerca volvulus 0.0054 0.023 0.1613
Plasmodium falciparum plasmepsin X 0.0112 0.0564 0.0564
Trichomonas vaginalis myo-inositol transporter, putative 0.0059 0.0258 0.1109
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0014 0.0004 0.0005
Brugia malayi cathepsin L-like precursor 0.0036 0.0129 0.0182
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0021 0.0029
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0295 0.042
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.026 0.0285
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0021 0.0029
Leishmania major protein kinase, putative 0.0036 0.0127 0.0556
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0717
Plasmodium falciparum calcium-dependent protein kinase 2 0.0128 0.0654 0.0654
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0146 0.0755 0.3302
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0146 0.0755 0.3302
Treponema pallidum threonyl-tRNA synthetase 0.0023 0.0058 0.1471
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0661 0.2863
Leishmania major hypothetical protein, conserved 0.0059 0.0258 0.113
Schistosoma mansoni sugar transporter 0.0059 0.0258 0.0368
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0023 0.0058 0.0684
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0045 0.0178 0.0196
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.026 0.1116
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.026 0.1137
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0023 0.0058 0.0237
Leishmania major cathepsin L-like protease 0.0204 0.1087 0.4755
Trypanosoma cruzi major cysteine proteinase, putative 0.0161 0.0838 0.3667
Brugia malayi major facilitator superfamily protein 0.0059 0.0258 0.0367
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0023 0.0058 0.0082
Brugia malayi hypothetical protein 0.0059 0.0258 0.0367
Brugia malayi hypothetical protein 0.0085 0.0405 0.0576
Leishmania major cysteine peptidase A (CPA) 0.0054 0.023 0.1005
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0045 0.0068
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.03 0.1313
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0047 0.0549
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0047 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0079 0.0328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Toxoplasma gondii hypothetical protein 0.0039 0.0146 0.0221
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0014 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0258 0.1109
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0034 0.015
Loa Loa (eye worm) hypothetical protein 0.0415 0.2285 0.3256
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0093 0.0454 0.5515
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0189 0.0999 0.4373
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0661 0.2863
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0018 0.0029 0.0041
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0146 0.0755 0.3302
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Brugia malayi Trypsin family protein 0.0018 0.0029 0.004
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0014 0.0004 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.004
Schistosoma mansoni glutamate receptor AMPA 0.0121 0.0611 0.087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0109 0.0545 0.0777
Plasmodium falciparum plasmepsin IV 0.0014 0.0004 0.0004
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0093 0.0454 0.1988
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0128 0.0654 0.0987
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0059 0.0258 0.2967
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0258 0.1109
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.011 0.0166
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.004
Leishmania major cathepsin L-like protease 0.0054 0.023 0.1005
Schistosoma mansoni hypothetical protein 0.0107 0.0531 0.0757
Onchocerca volvulus Cathepsin L homolog 0.0054 0.023 0.1613
Leishmania major aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Plasmodium vivax aspartyl protease, putative 0.0112 0.0564 0.056
Plasmodium falciparum aspartate--tRNA ligase 0.0014 0.0004 0.0004
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0129 0.066 0.0723
Echinococcus granulosus insulin receptor 0.039 0.2139 0.3048
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0156
Treponema pallidum glycyl-tRNA synthetase 0.0014 0.0005 0.0009
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.026 0.0392
Loa Loa (eye worm) intermediate filament protein 0.0112 0.056 0.0797
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0129 0.066 0.0723
Brugia malayi jmjC domain containing protein 0.0017 0.0021 0.0029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0109 0.0119
Onchocerca volvulus 0.0112 0.056 0.3946
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0109 0.0477
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.03 0.1313
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0054 0.023 0.0984
Loa Loa (eye worm) hypothetical protein 0.0212 0.1131 0.1611
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0043 0.0186
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0023 0.0058 0.1471
Plasmodium falciparum cysteine proteinase falcipain 1 0.0028 0.0082 0.0082
Echinococcus granulosus Mastin 0.0018 0.0029 0.0041
Brugia malayi glycyl-tRNA synthetase 0.0023 0.0058 0.0082
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0531 0.0756
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0014 0.0005 0.0009
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0023 0.0058 0.0082
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0004 0.0005
Echinococcus multilocularis epidermal growth factor receptor 0.0854 0.4776 0.5236
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0231 0.0254
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0054 0.023 0.0326
Loa Loa (eye worm) aspartyl protease 6 0.0014 0.0004 0.0004
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0029 0.0031
Echinococcus granulosus lipoxygenase domain containing protein 0.0085 0.0405 0.0577
Leishmania major cathepsin L-like protease 0.0054 0.023 0.1005
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0018 0.0029 0.0031
Plasmodium falciparum asparagine--tRNA ligase 0.0014 0.0004 0.0004
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0418 0.2298 0.3274
Brugia malayi Pre-SET motif family protein 0.0033 0.011 0.0156
Loa Loa (eye worm) fibroinase 0.0054 0.023 0.0326
Mycobacterium ulcerans integral membrane transport protein 0.0059 0.0258 0.3235
Chlamydia trachomatis lysine--tRNA ligase 0.0093 0.0454 1
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0142 0.0202
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0021 0.0023
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0206 0.0293
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Leishmania major asparaginyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Onchocerca volvulus 0.0059 0.0258 0.1816
Trypanosoma cruzi hexose transporter 0.013 0.0661 0.2891
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0135 0.0192
Brugia malayi Glutamate receptor 1 precursor 0.0121 0.0611 0.0869
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0045 0.0178 0.0196
Loa Loa (eye worm) major facilitator superfamily transporter 0.0059 0.0258 0.0367
Schistosoma mansoni hypothetical protein 0.0418 0.2298 0.3274
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Brugia malayi Furin-like cysteine rich region family protein 0.1248 0.7017 1
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0004 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.011 0.0157
Echinococcus granulosus GPCR family 2 0.0049 0.0205 0.0293
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0505 0.2797 0.3986
Onchocerca volvulus 0.0059 0.0258 0.1816
Trichomonas vaginalis sugar transporter, putative 0.013 0.0661 0.2863
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0028 0.0082 0.0116
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0675 0.3762 0.5672
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0014 0.0004 0.0006
Brugia malayi Cathepsin L-like precursor 0.0054 0.023 0.0326
Onchocerca volvulus 0.0091 0.0441 0.3105
Plasmodium vivax proline--tRNA ligase, putative 0.0146 0.0755 0.0751
Echinococcus multilocularis CAAX prenyl protease 2 0.0189 0.0999 0.1095
Echinococcus granulosus cathepsin L 0.0028 0.0082 0.0116
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0749 0.1066
Trypanosoma brucei unspecified product 0.0013 0 0.0001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0109 0.0119
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0333 0.0474
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0047 0.0549
Loa Loa (eye worm) inositol-1 0.0037 0.0135 0.0191
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0023 0.0058 0.0082
Mycobacterium tuberculosis Probable aminotransferase 0.0152 0.0789 1
Schistosoma mansoni single-minded 0.0105 0.0519 0.074
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.03 0.0427
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0189 0.0999 0.4373
Brugia malayi Pre-SET motif family protein 0.0224 0.1196 0.1704
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0129 0.0544
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0018 0.0029 0.004
Leishmania major hypothetical protein, conserved 0.0017 0.0021 0.0091
Brugia malayi Major Facilitator Superfamily protein 0.0059 0.0258 0.0367
Echinococcus multilocularis synaptic vesicle 2 protein 0.0059 0.0258 0.0283
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Leishmania major C-8 sterol isomerase-like protein 0.0415 0.2285 1
Schistosoma mansoni cpg binding protein 0.003 0.0097 0.0139
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0029 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0021 0.0029
Onchocerca volvulus 0.005 0.0206 0.1446
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0109 0.0477
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0142 0.0156
Plasmodium falciparum glycine--tRNA ligase 0.0014 0.0005 0.0005
Echinococcus multilocularis glutamate receptor 2 0.0129 0.066 0.0723
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0189 0.0999 0.4373
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0205 0.0293
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 0.465
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0079 0.0374 0.4506
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.0198
Onchocerca volvulus Huntingtin homolog 0.0263 0.1419 1
Schistosoma mansoni glutamate receptor NMDA 0.0218 0.1165 0.166
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0129 0.066 0.094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0129 0.0544
Onchocerca volvulus 0.0112 0.056 0.3946
Echinococcus granulosus cathepsin l cysteine peptidase 0.0054 0.023 0.0327
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0028 0.0082 0.0116
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0036 0.0127 0.0556
Leishmania major hypothetical protein, conserved 0.0021 0.0043 0.0186
Schistosoma mansoni hypothetical protein 0.0049 0.0205 0.0293
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0034 0.0048
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0029 0.0041
Echinococcus granulosus enteropeptidase 0.0018 0.0029 0.0041
Brugia malayi aspartic protease BmAsp-2, identical 0.0014 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Trypanosoma cruzi cysteine peptidase, putative 0.0204 0.1087 0.4755
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0021 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0278 0.0396
Brugia malayi Cathepsin L-like precursor 0.0054 0.023 0.0326
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0093 0.0454 0.1988
Toxoplasma gondii lysine-tRNA ligase 0.0093 0.0454 0.0685
Schistosoma mansoni hypothetical protein 0.0072 0.0333 0.0474
Loa Loa (eye worm) hypothetical protein 0.0125 0.0637 0.0906
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.023 0.0984
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0109 0.0119
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0109 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0023 0.0058 0.0254
Leishmania major GTP-binding protein, putative 0.0021 0.0045 0.0198
Toxoplasma gondii hypothetical protein 0.0027 0.0078 0.0117
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0286 0.0407
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0023 0.0058 0.0082
Brugia malayi Cathepsin L-like precursor 0.0036 0.0129 0.0182
Schistosoma mansoni DNA polymerase eta 0.0019 0.0034 0.0049
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0023 0.0058 0.0684
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0369 0.0366
Trypanosoma cruzi histidyl-tRNA synthetase 0.0014 0.0005 0.0021
Echinococcus granulosus solute carrier family 22 0.0059 0.0258 0.0368
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0029 0.0041
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0043 0.0109
Toxoplasma gondii aspartyl protease ASP3 0.0112 0.0564 0.085
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0128 0.0654 0.0931
Chlamydia trachomatis hypothetical protein 0.0039 0.0146 0.3154
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Trypanosoma cruzi cysteine peptidase, putative 0.0054 0.023 0.1005
Plasmodium falciparum histidine--tRNA ligase, putative 0.0014 0.0005 0.0005
Plasmodium vivax unspecified product 0.0028 0.0082 0.0078
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0205 0.0225
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0125 0.0637 0.0907
Echinococcus granulosus Threonyl tRNA synthetase C 0.0023 0.0058 0.0083
Schistosoma mansoni protein kinase 0.0128 0.0654 0.0932
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0047 0.0174
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.015
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0023 0.0058 0.0581
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.2251 0.2468
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0167 0.0252
Echinococcus multilocularis glutamate receptor 2 0.0085 0.0406 0.0445
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.1269 0.1809
Mycobacterium ulcerans hypothetical protein 0.0021 0.0043 0.0486
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0014 0.0004 0.0005
Brugia malayi Doublecortin family protein 0.0085 0.0405 0.0576
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0025 0.0035
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0125 0.0637 0.0906
Plasmodium falciparum hexose transporter 0.0418 0.2298 0.2298
Schistosoma mansoni glycyl-tRNA synthetase 0.0023 0.0058 0.0083
Plasmodium vivax histidine--tRNA ligase, putative 0.0014 0.0005 0.0001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0505 0.2797 0.3066
Entamoeba histolytica cysteine protease, putative 0.0028 0.0082 0.0817
Brugia malayi CAAX amino terminal protease family protein 0.0189 0.0999 0.1423
Schistosoma mansoni sugar transporter 0.0059 0.0258 0.0368
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0045 0.0178 0.0254
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0216 0.2325
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0109 0.0119
Entamoeba histolytica hypothetical protein 0.0072 0.0333 0.3329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Mycobacterium ulcerans integral membrane protein 0.0039 0.0146 0.1808
Onchocerca volvulus Cathepsin L homolog 0.0054 0.023 0.1613
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0047 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0082 0.0339
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0369 0.0369
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0079 0.0374 0.4506
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Loa Loa (eye worm) sugar transporter 0.0418 0.2298 0.3274
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0051 0.0217 0.0308
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0035
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0125 0.0637 0.0698
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.026 0.1137
Toxoplasma gondii aspartate-tRNA ligase 0.0014 0.0004 0.0007
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0185 0.0262
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0726 0.1034
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0093 0.0454 0.5733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Plasmodium vivax unspecified product 0.0018 0.0025 0.0022
Schistosoma mansoni lysyl-tRNA synthetase 0.0093 0.0454 0.0647
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0025 0.0111
Plasmodium falciparum LCCL domain-containing protein 0.0085 0.0405 0.0405
Brugia malayi hypothetical protein 0.0351 0.192 0.2736
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0717
Echinococcus multilocularis geminin 0.017 0.0888 0.0974
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma brucei sugar transporter, putative 0.0059 0.0258 0.113
Trypanosoma cruzi glucose transporter, putative 0.0059 0.0258 0.113
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0014 0.0004 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0082 0.0357
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0128 0.0654 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Onchocerca volvulus 0.0059 0.0258 0.1816
Brugia malayi hypoxia-induced factor 1 0.0324 0.1766 0.2515
Echinococcus granulosus solute carrier family 22 0.0059 0.0258 0.0368
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0418 0.2298 0.2519
Mycobacterium ulcerans hypothetical protein 0.0018 0.0029 0.0309
Plasmodium falciparum protein kinase 7 0.118 0.6633 0.6633
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0135 0.0589
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0023 0.0058 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.015
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0109 0.0105
Schistosoma mansoni glucose transport protein 0.0418 0.2298 0.3274
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0082 0.0389 0.1679
Treponema pallidum hypothetical protein 0.0039 0.0146 0.3889
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0604 0.0859
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0028 0.0082 0.0357
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0156 0.0812 0.1157
Echinococcus multilocularis solute carrier family 22 0.0059 0.0258 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0043 0.0186
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0021 0.0023
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.039 0.2139 0.2345
Brugia malayi hypothetical protein 0.0014 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Plasmodium falciparum lysine--tRNA ligase 0.0093 0.0454 0.0454
Schistosoma mansoni memapsin-2 (A01 family) 0.0014 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0082 0.0339
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0295 0.042
Echinococcus granulosus epidermal growth factor receptor 0.0854 0.4776 0.6806
Loa Loa (eye worm) hypothetical protein 0.0263 0.1419 0.2021
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0129 0.066 0.0723
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.026 0.1116
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0014 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0129 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0204 0.1087 0.4755
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0079 0.0328
Leishmania major glucose transporter, lmgt1 0.013 0.0661 0.2891
Schistosoma mansoni glutamate receptor kainate 0.0121 0.0611 0.087
Plasmodium falciparum plasmepsin VI 0.0014 0.0004 0.0004
Echinococcus multilocularis lysyl tRNA synthetase 0.0093 0.0454 0.0498
Echinococcus multilocularis insulin receptor 0.039 0.2139 0.2345
Echinococcus multilocularis glutamate receptor 2 0.0121 0.0611 0.067
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0128 0.0654 0.0932
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0021 0.0091
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0039 0.0146 0.1484
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0059 0.0258 0.6956
Brugia malayi lysyl-tRNA synthetase 0.0093 0.0454 0.0646
Giardia lamblia Lysyl-tRNA synthetase 0.0093 0.0454 0.4522
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.023 0.0984
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0369 0.0405
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0205 0.0292
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0022 0.0047 0.118
Leishmania major cathepsin L-like protease 0.0204 0.1087 0.4755
Plasmodium vivax sugar transporter, putative 0.0059 0.0258 0.0255
Onchocerca volvulus 0.0109 0.0545 0.384
Brugia malayi jmjC domain containing protein 0.0017 0.0021 0.0029
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0109 0.0155
Brugia malayi aspartic protease BmAsp-1, identical 0.0014 0.0004 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Echinococcus granulosus cpg binding protein 0.003 0.0097 0.0139
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0021 0.0023
Onchocerca volvulus 0.0054 0.023 0.1613
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0004 0.0005
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0415 0.2285 1
Echinococcus multilocularis microtubule associated protein 2 0.0691 0.3849 0.422
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0216 0.0308
Echinococcus multilocularis histidyl tRNA synthetase 0.0014 0.0005 0.0005
Echinococcus multilocularis tyrosine kinase 0.0013 0.0001 0.0001
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0047 0.0066
Entamoeba histolytica hypothetical protein 0.0023 0.0058 0.0576
Loa Loa (eye worm) hypothetical protein 0.0128 0.0654 0.0931
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Leishmania major glucose transporter/membrane transporter D2, putative 0.013 0.0661 0.2891
Echinococcus granulosus Polycystic kidney disease protein 0.0085 0.0405 0.0577
Loa Loa (eye worm) 63kd antigen 0.0014 0.0004 0.0005
Echinococcus granulosus solute carrier family 22 0.0059 0.0258 0.0368
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0027 0.0079 0.1662
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0167 0.0252
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0216 0.2408
Trypanosoma brucei glucose transporter, putative 0.013 0.0661 0.2891
Echinococcus granulosus lamin 0.0112 0.056 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0258 0.1109
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0367
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.011 0.0157
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0047 0.0174
Leishmania major lysyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0014 0.0005 0.0047
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0047 0.0174
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0014 0.0005 0.0006
Schistosoma mansoni glucose transporter 0.0059 0.0258 0.0368
Echinococcus granulosus dnaJ subfamily B 0.0409 0.2251 0.3208
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0125 0.0637 0.0906
Plasmodium vivax hexose transporter 0.0418 0.2298 0.2295
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0045 0.0041
Schistosoma mansoni loxhd1 0.0085 0.0405 0.0577
Loa Loa (eye worm) hypothetical protein 0.0036 0.0129 0.0182
Echinococcus granulosus glutamate NMDA receptor subunit 0.0183 0.0965 0.1375
Toxoplasma gondii glycyl-tRNA synthetase 0.0023 0.0058 0.0088
Echinococcus multilocularis receptor type guanylyl cyclase 0.0013 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0059 0.0258 0.1109
Echinococcus granulosus glycoprotein Antigen 5 0.0018 0.0029 0.0041
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.026 0.037
Schistosoma mansoni lysyl-tRNA synthetase 0.0093 0.0454 0.0647
Brugia malayi jmjC domain containing protein 0.0017 0.0021 0.0029
Echinococcus granulosus tumor protein p63 0.0338 0.1846 0.2631
Leishmania major aspartyl-tRNA synthetase, putative 0.0014 0.0004 0.0019
Echinococcus multilocularis enteropeptidase 0.0018 0.0029 0.0031
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0189 0.0999 0.1424
Brugia malayi hypothetical protein 0.0014 0.0004 0.0004
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0004 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.011 0.0157
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0025 0.0035
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0418 0.2298 0.3274
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0021 0.003
Plasmodium vivax multidomain scavenger receptor, putative 0.0085 0.0405 0.0401

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 150 nM Inhibition of porcine pepsin at pH 4 ChEMBL. 3126296

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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