Detailed information for compound 434577

Basic information

Technical information
  • TDR Targets ID: 434577
  • Name: N-[4-[(4-amino-5-sulfanylidene-1H-1,2,4-triaz ol-3-yl)methyl]-1,3-thiazol-2-yl]-2-chloroace tamide
  • MW: 304.78 | Formula: C8H9ClN6OS2
  • H donors: 2 H acceptors: 4 LogP: 0.82 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nn1c(Cc2csc(n2)NC(=O)CCl)nnc1S
  • InChi: 1S/C8H9ClN6OS2/c9-2-6(16)12-7-11-4(3-18-7)1-5-13-14-8(17)15(5)10/h3H,1-2,10H2,(H,14,17)(H,11,12,16)
  • InChiKey: ZLIAMJQWKIUHTK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[(4-amino-5-thioxo-1H-1,2,4-triazol-3-yl)methyl]thiazol-2-yl]-2-chloro-acetamide
  • N-[4-[(4-amino-5-thioxo-1H-1,2,4-triazol-3-yl)methyl]-2-thiazolyl]-2-chloroacetamide
  • N-[4-[(4-azanyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)methyl]-1,3-thiazol-2-yl]-2-chloro-ethanamide
  • N-[4-[(4-amino-5-sulfanylidene-1H-1,2,4-triazol-3-yl)methyl]-1,3-thiazol-2-yl]-2-chloro-ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin-dependent kinase 5 Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 5, regulatory subunit 1 (p35) References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni cyclin-dependent kinase 5 activator Get druggable targets OG5_133447 All targets in OG5_133447
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 5 activator 1 Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Schistosoma japonicum Cyclin-dependent kinase 5 activator 2 precursor, putative Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 5 260 aa 307 aa 28.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0523 0.3106 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0109 0.0521
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0035 0.0122 0.0201
Loa Loa (eye worm) hypothetical protein 0.0035 0.0122 0.0384
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Loa Loa (eye worm) jmjC domain-containing protein 0.0188 0.1057 0.3398
Brugia malayi Latrophilin receptor protein 2 0.0096 0.0494 0.1579
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0042 0.0131
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0304 0.1764 0.5674
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0014 0.0036
Schistosoma mansoni zinc finger protein 0.0047 0.0194 0.0231
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0096 0.0322
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.04
Loa Loa (eye worm) hypothetical protein 0.0446 0.2633 0.8475
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0032 0.0103 0.0123
Leishmania major pteridine reductase 1 0.0028 0.0075 0.0327
Trichomonas vaginalis hypothetical protein 0.0024 0.0054 0.0144
Entamoeba histolytica acyl-coA synthetase, putative 0.012 0.0643 0.5787
Brugia malayi nuclear hormone receptor family member odr-7 0.0032 0.0103 0.032
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0084 0.0376
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.0164 0.0179
Onchocerca volvulus Serine\/threonine kinase homolog 0.0197 0.1111 0.4042
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0056 0.0152
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Onchocerca volvulus 0.0057 0.0256 0.0773
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Echinococcus granulosus cyclin dependent kinase 5 0.0053 0.0229 0.0256
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0035 0.0122 0.0431
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0103 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Loa Loa (eye worm) jmjC domain-containing protein 0.0117 0.0625 0.2004
Giardia lamblia Kinase, CMGC CDK 0.0053 0.0229 0.1917
Plasmodium vivax importin-beta 2, putative 0.003 0.0091 0.0299
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Brugia malayi nuclear hormone receptor family member nhr-6 0.0032 0.0103 0.032
Onchocerca volvulus 0.0035 0.0122 0.0262
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0028 0.0075 0.0073
Schistosoma mansoni hypothetical protein 0.0096 0.0494 0.0589
Echinococcus multilocularis expressed protein 0.0035 0.0119 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0133 0.0476
Brugia malayi Nuclear hormone receptor E75 0.0032 0.0103 0.032
Echinococcus granulosus zinc finger protein 0.0047 0.0194 0.0215
Trichomonas vaginalis chromobox protein, putative 0.0148 0.081 0.3309
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.1111 0.1324
Schistosoma mansoni RAR-like nuclear receptor 0.0068 0.0325 0.0387
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0068 0.0325 0.1033
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.0601
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0028 0.0075 0.0234
Loa Loa (eye worm) hypothetical protein 0.0087 0.0438 0.1402
Brugia malayi AMP-binding enzyme family protein 0.012 0.0643 0.2059
Echinococcus granulosus dna polymerase kappa 0.0042 0.0164 0.0179
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Schistosoma mansoni steroid hormone receptor ad4bp 0.0068 0.0325 0.0387
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Schistosoma mansoni retinoic acid receptor RXR 0.0068 0.0325 0.0387
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0119 0.0105
Plasmodium falciparum protein kinase 5 0.0053 0.0229 0.0876
Echinococcus granulosus Spectrin alpha actinin 0.0039 0.0142 0.0152
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0036 0.0127 0.0113
Schistosoma mansoni hypothetical protein 0.0096 0.0494 0.0589
Trichomonas vaginalis hypothetical protein 0.0409 0.2407 1
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0028 0.0075 0.0327
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0054 0.0064
Loa Loa (eye worm) hypothetical protein 0.0144 0.0789 0.2532
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0426 0.1704
Onchocerca volvulus 0.0025 0.0061 0.0029
Echinococcus multilocularis cyclin dependent kinase 0.0053 0.0229 0.0215
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.022 0.0841
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0035 0.0122 0.0431
Brugia malayi chromobox protein homolog 3 0.0083 0.0412 0.1316
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0167 0.1352
Loa Loa (eye worm) hypothetical protein 0.0096 0.0494 0.1582
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0583 0.068
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Entamoeba histolytica hypothetical protein 0.0111 0.0583 0.5252
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.012 0.0643 0.2434
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0086 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0068 0.0325 0.1036
Onchocerca volvulus 0.0028 0.0075 0.0082
Schistosoma mansoni chromobox protein 0.0148 0.081 0.0965
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0485
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.1061 0.1049
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.0601
Brugia malayi AMP-binding enzyme family protein 0.012 0.0643 0.2059
Trypanosoma brucei polo-like protein kinase 0.0197 0.1111 0.6382
Loa Loa (eye worm) hypothetical protein 0.0029 0.0086 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0119 0.0419
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0035 0.0122 0.1101
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0031 0.0098 0.0116
Echinococcus multilocularis zinc finger protein 0.0047 0.0194 0.018
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0649 0.0774
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.0103 0.019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0426 0.1704
Schistosoma mansoni dihydropteridine reductase 0.0028 0.0075 0.009
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0086 0.0357
Loa Loa (eye worm) hypothetical protein 0.0035 0.0122 0.0384
Echinococcus granulosus dnaJ subfamily B 0.0815 0.4891 0.5824
Brugia malayi orphan nuclear receptor NR2E1 0.0032 0.0103 0.032
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0035 0.0122 0.0431
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0068 0.0325 0.1036
Brugia malayi Nuclear hormone receptor E75 0.0032 0.0103 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Schistosoma mansoni acetyl-CoA synthetase 0.0035 0.0122 0.0146
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.009 0.0076
Schistosoma mansoni nuclear receptor 0.0032 0.0103 0.0123
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0088 0.0402
Loa Loa (eye worm) hypothetical protein 0.0037 0.0132 0.0416
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0068 0.0325 0.0311
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.173 1
Echinococcus granulosus cyclin dependent kinase 1 0.0053 0.0229 0.0256
Echinococcus granulosus FTZ F1 alpha 0.0068 0.0325 0.0371
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0028 0.0075 0.0327
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0028 0.0075 0.0313
Echinococcus multilocularis muscleblind protein 1 0.0446 0.2633 0.2622
Plasmodium falciparum importin beta, putative 0.003 0.0091 0.0299
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0068 0.0325 0.0387
Trypanosoma brucei ISWI complex protein 0.0031 0.0097 0.0453
Plasmodium vivax protein kinase Crk2 0.0053 0.0229 0.0876
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0042 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0084 0.0376
Loa Loa (eye worm) hypothetical protein 0.0304 0.1764 0.5675
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.009 0.0091
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0904 0.0891
Loa Loa (eye worm) hypothetical protein 0.0052 0.0221 0.0704
Schistosoma mansoni thyroid hormone receptor 0.0068 0.0325 0.0387
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0054 0.0144
Echinococcus multilocularis fatty acid binding protein FABP2 0.0035 0.0118 0.0104
Echinococcus multilocularis cyclin dependent kinase 5 0.0053 0.0229 0.0215
Echinococcus granulosus dna polymerase eta 0.007 0.0334 0.0382
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0037 0.013 0.0116
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.0075 0.0234
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0068 0.0325 0.1036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0068 0.0325 0.0387
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Echinococcus granulosus ecdysone induced protein 78C 0.0068 0.0325 0.0371
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0409 0.2407 1
Toxoplasma gondii exonuclease III APE 0.0019 0.002 0.0081
Brugia malayi ecdysone receptor 0.0032 0.0103 0.032
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.016 0.0588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0068 0.0325 0.1036
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0451 0.1807
Loa Loa (eye worm) hypothetical protein 0.009 0.0457 0.1462
Schistosoma mansoni hypothetical protein 0.0111 0.0583 0.0696
Loa Loa (eye worm) heterochromatin protein 1 0.0148 0.081 0.2599
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1061 0.1265
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0068 0.0325 0.0387
Mycobacterium ulcerans acyl-CoA synthetase 0.012 0.0643 0.2611
Echinococcus granulosus expressed protein 0.0035 0.0119 0.0126
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0381
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0178 0.0664
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0053 0.0229 0.1223
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0265 0.1026
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0068 0.0325 0.0387
Loa Loa (eye worm) hypothetical protein 0.0133 0.0719 0.2306
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0053 0.0229 0.0256
Giardia lamblia PHD finger protein 15 0.0091 0.0464 0.407
Brugia malayi Protein kinase domain containing protein 0.0053 0.0229 0.0724
Schistosoma mansoni fatty acid binding protein 0.0035 0.0118 0.0141
Echinococcus granulosus ETS transcription factor Elf 1 0.0021 0.0035 0.0024
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0028 0.0075 0.0313
Trichomonas vaginalis ran, putative 0.0022 0.0042 0.0094
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0086 0.0267
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0282
Loa Loa (eye worm) hypothetical protein 0.0309 0.1797 0.5782
Onchocerca volvulus 0.0035 0.0122 0.0262
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0054 0.0144
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0028 0.0075 0.0234
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0054 0.004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0068 0.0325 0.0311
Echinococcus granulosus histone acetyltransferase KAT2B 0.0154 0.0847 0.0995
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0035 0.0122 0.0508
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0035 0.0122 0.0431
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.0054 0.016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0769 0.4383
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0091 0.0417
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.009 0.0457 0.1635
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Onchocerca volvulus 0.0032 0.0103 0.019
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Trypanosoma cruzi DNA polymerase eta, putative 0.007 0.0334 0.1839
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0068 0.0325 0.1033
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.1111 0.6382
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Schistosoma mansoni nuclear receptor nhr-48 0.0032 0.0103 0.0123
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0086 0.0086
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0053 0.0229 0.095
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0035 0.0122 0.0431
Trypanosoma brucei unspecified product 0.0029 0.0084 0.0376
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0304 0.1764 0.5675
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0032 0.0103 0.0089
Schistosoma mansoni DNA polymerase eta 0.007 0.0334 0.0398
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.012 0.0643 0.2434
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0035 0.002
Loa Loa (eye worm) RecQ helicase 0.0044 0.0178 0.0564
Brugia malayi hypothetical protein 0.0024 0.0054 0.016
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0086 0.0267
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0409 0.2407 1
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0163 0.0517
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0164 0.0604
Schistosoma mansoni microtubule-associated protein tau 0.0681 0.4073 0.4855
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0054 0.0144
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0381
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.0094
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0068 0.0325 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0265 0.1026
Entamoeba histolytica hypothetical protein 0.0024 0.0054 0.0485
Loa Loa (eye worm) hypothetical protein 0.0208 0.1176 0.3781
Plasmodium falciparum acyl-CoA synthetase 0.009 0.0457 0.183
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0031 0.0098 0.01
Loa Loa (eye worm) steroid hormone receptor 0.0068 0.0325 0.1036
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0197 0.1111 0.357
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0035 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0866 0.3547
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0122 0.0601
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0309 0.1797 0.2129
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.0229 0.0727
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Echinococcus multilocularis geminin 0.1386 0.8388 0.8386
Onchocerca volvulus Bile acid receptor homolog 0.0068 0.0325 0.1036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0091 0.0417
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0054 0.0064
Loa Loa (eye worm) D-ets-2 protein 0.0021 0.0035 0.0102
Schistosoma mansoni DNA helicase recq5 0.003 0.009 0.0108
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.0229 0.2059
Loa Loa (eye worm) hypothetical protein 0.0148 0.0811 0.2605
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.012 0.0643 0.2611
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Loa Loa (eye worm) fli-1 protein 0.044 0.2598 0.8363
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.0229 0.0215
Mycobacterium ulcerans oxidoreductase 0.0028 0.0075 0.0234
Brugia malayi CXXC zinc finger family protein 0.0057 0.0256 0.0812
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0068 0.0325 0.1036
Echinococcus multilocularis Spectrin alpha actinin 0.0039 0.0142 0.0128
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0156 0.0799
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0122 0.0384
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0035 0.0122 0.0431
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0084 0.0376
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0086 0.0086
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0028 0.0075 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0229 0.0273
Loa Loa (eye worm) ets-domain-containing protein 0.0021 0.0035 0.0102
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0042 0.0033
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0114 0.0475
Onchocerca volvulus 0.0032 0.0103 0.019
Loa Loa (eye worm) DR-78 0.0032 0.0103 0.0324
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0145 0.0793 0.2545
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0028 0.0075 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0036 0.0127 0.04
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0162 0.0835
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0054 0.0047
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0058 0.0162
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0103 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0325 0.0371
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0904 0.2901
Trypanosoma brucei oxidoreductase-like protein 0.0028 0.0075 0.0327
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0354 0.0406
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0354 0.0341
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0178 0.0164
Brugia malayi Heterochromatin protein 1 0.0148 0.081 0.2596
Loa Loa (eye worm) helicase 0.0024 0.0054 0.0164
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Echinococcus multilocularis muscleblind protein 0.0446 0.2633 0.2622
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.0122
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Brugia malayi photoreceptor-specific nuclear receptor 0.0068 0.0325 0.1033
Loa Loa (eye worm) hypothetical protein 0.0078 0.0385 0.1231
Echinococcus granulosus peregrin 0.01 0.0517 0.06
Brugia malayi PHD-finger family protein 0.0037 0.0132 0.0412
Schistosoma mansoni ran 0.0022 0.0042 0.005
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0164 0.0844
Schistosoma mansoni importin beta-1 0.003 0.0091 0.0108
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.0229 0.0727
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0037 0.013 0.0138
Schistosoma mansoni coup transcription factor 0.0068 0.0325 0.0387
Echinococcus granulosus GA binding protein alpha chain 0.0145 0.0793 0.093
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0175 0.0209
Loa Loa (eye worm) hypothetical protein 0.0156 0.0862 0.2769
Mycobacterium ulcerans fatty-acid-CoA ligase 0.009 0.0457 0.183
Schistosoma mansoni ets-related 0.044 0.2598 0.3097
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.0075 0.0234
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0409 0.2407 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0218 0.1163
Loa Loa (eye worm) hypothetical protein 0.009 0.0457 0.1462
Toxoplasma gondii propionate-CoA ligase 0.0035 0.0122 0.0508
Loa Loa (eye worm) hypothetical protein 0.0094 0.0482 0.1544
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0207 0.0247
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0122 0.0601
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0197 0.1112 0.4047
Onchocerca volvulus Protein ultraspiracle homolog 0.0068 0.0325 0.1036
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0068 0.0325 0.1036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0133 0.0476
Schistosoma mansoni zinc finger protein 0.0031 0.0097 0.0116
Echinococcus granulosus Chromo domain 0.0024 0.0054 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0054 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Echinococcus multilocularis FTZ F1 alpha 0.0068 0.0325 0.0311
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0109 0.0521
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.0494 0.0573
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0035 0.0122 0.0381
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0504 0.203
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.0229 0.1223
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0042 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0068 0.0325 0.1033
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0164 0.0604
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Brugia malayi nuclear receptor RXR 0.0036 0.0127 0.0396
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0649 0.3684
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0119 0.0125
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.009 0.0278
Echinococcus multilocularis protein C ets 2 0.0021 0.0035 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0447
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0032 0.0103 0.0107
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.0229 0.2059
Onchocerca volvulus Alhambra homolog 0.0091 0.0464 0.1567
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0028 0.0075 0.0234
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0649 0.2638
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.009 0.065
Brugia malayi CHD4 protein 0.0031 0.0098 0.0301
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0021 0.0035 0.002
Loa Loa (eye worm) bromodomain containing protein 0.004 0.015 0.0474
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0325 0.0387
Brugia malayi hypothetical protein 0.0036 0.0127 0.0396
Loa Loa (eye worm) acetyltransferase 0.0163 0.0904 0.2903
Trypanosoma brucei pteridine reductase 1 0.0028 0.0075 0.0327
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0054 0.0224
Schistosoma mansoni hypothetical protein 0.0091 0.0464 0.0553
Onchocerca volvulus 0.0068 0.0325 0.1036
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0122 0.0431
Echinococcus granulosus ETS domain containing protein Elk 1 0.0021 0.0035 0.0024
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0068 0.0325 0.0371
Brugia malayi RNA, U transporter 1 0.0086 0.0432 0.1378
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0091 0.0377
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0032 0.0103 0.0324
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0086 0.0389
Echinococcus multilocularis GPCR, family 2 0.0096 0.0494 0.048
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0197 0.1111 0.131
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0091 0.0464 0.0553
Loa Loa (eye worm) hypothetical protein 0.0446 0.2633 0.8475
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0129 0.0695 0.0682
Schistosoma mansoni bromodomain containing protein 0.0016 0.0003 0.0004
Brugia malayi Ets-domain containing protein 0.0145 0.0793 0.2542
Leishmania major hypothetical protein, conserved 0.0025 0.0058 0.0226
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0021 0.0035 0.0102
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0056 0.0152
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0054 0.0144
Toxoplasma gondii PHD-finger domain-containing protein 0.0091 0.0464 0.1926
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0066 0.0273
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Brugia malayi hypothetical protein 0.0032 0.0103 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0412 0.1646
Trypanosoma brucei unspecified product 0.0042 0.0164 0.0844
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0021 0.0035 0.0102
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0086 0.0278
Brugia malayi transcription factor E74 isoform 0.0021 0.0035 0.0098
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0028 0.0075 0.009
Echinococcus multilocularis chromobox protein 2 0.0024 0.0054 0.004
Trypanosoma cruzi ISWI complex protein 0.0031 0.0097 0.0453
Schistosoma mansoni gabp alpha 0.0145 0.0793 0.0945
Schistosoma mansoni zinc finger protein 0.0032 0.0103 0.0123
Echinococcus multilocularis GA binding protein alpha chain 0.0145 0.0793 0.078
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0167 0.1503
Echinococcus multilocularis Chromo domain 0.0024 0.0054 0.004
Entamoeba histolytica hypothetical protein 0.0024 0.0054 0.0485
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0056 0.0212
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0649 0.0636
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0028 0.0075 0.0327
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0114 0.0555
Echinococcus granulosus cyclin dependent kinase 0.0053 0.0229 0.0256
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0769 0.4383
Loa Loa (eye worm) hypothetical protein 0.009 0.0457 0.1462
Echinococcus granulosus nuclear receptor nhr 48 0.0032 0.0103 0.0107
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.1061 0.1251
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0058 0.0162
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0409 0.2407 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0464 0.1484
Plasmodium vivax hypothetical protein, conserved 0.0033 0.011 0.0377
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0122 0.0431
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0054 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Brugia malayi jmjC domain containing protein 0.0029 0.0086 0.0264
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.009 0.0457 0.183
Schistosoma mansoni chromobox protein 0.0024 0.0054 0.0064
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0409 0.2407 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0028 0.0075 0.0327
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0021 0.0035 0.0041
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0164 0.015
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0649 0.0759
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0381
Loa Loa (eye worm) nuclear receptor NHR-67 0.0032 0.0103 0.0324
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0058 0.0226
Schistosoma mansoni elf1 0.0021 0.0035 0.0041
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0054 0.016
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.002 0.0176
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0086 0.0102
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0162 0.0835
Schistosoma mansoni hypothetical protein 0.0815 0.4891 0.5831
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0086 0.0357
Echinococcus multilocularis dnaJ subfamily B 0.0815 0.4891 0.4884
Echinococcus granulosus muscleblind protein 0.0446 0.2633 0.3127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0102
Echinococcus granulosus fatty acid binding protein FABP2 0.0035 0.0118 0.0124
Brugia malayi cell division control protein 2 homolog 0.0053 0.0229 0.0724
Schistosoma mansoni hypothetical protein 0.0096 0.0494 0.0589
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0068 0.0325 0.1033
Brugia malayi ImpB/MucB/SamB family protein 0.007 0.0334 0.1063
Schistosoma mansoni jumonji/arid domain-containing protein 0.0117 0.0625 0.0745
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0133 0.0476
Toxoplasma gondii PHD-finger domain-containing protein 0.0091 0.0464 0.1926
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0247 0.1416 0.1674
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0247 0.1416 0.1404
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0309 0.1797 0.1785
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0035 0.0122 0.0381
Plasmodium vivax acetyl-CoA synthetase, putative 0.0035 0.0122 0.0431
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0088 0.0367
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0122 0.0601
Brugia malayi PHD-finger family protein 0.0058 0.0261 0.0827
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0207 0.0231
Brugia malayi nuclear hormone receptor 0.0068 0.0325 0.1033
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0164 0.0604
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.0103 0.019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1061 0.1265
Schistosoma mansoni hypothetical protein 0.0208 0.1176 0.1402
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.173 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0068 0.0325 0.1036
Echinococcus multilocularis ETS transcription factor Elf 5 0.0021 0.0035 0.002
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0069 0.0209
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0648 0.0773
Schistosoma mansoni hypothetical protein 0.0039 0.0142 0.0169
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.009 0.0076
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.0023
Echinococcus granulosus phd:f box containing protein 0.0029 0.0086 0.0086
Brugia malayi jmjC domain containing protein 0.0029 0.0086 0.0264
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0042 0.0174
Loa Loa (eye worm) hypothetical protein 0.012 0.0643 0.2062
Echinococcus granulosus microtubule associated protein 2 0.0681 0.4073 0.4847
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0096 0.0494 0.048
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0068 0.0325 0.0387
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0054 0.0064
Loa Loa (eye worm) hypothetical protein 0.0065 0.0303 0.0967
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0056 0.0152
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0068 0.0325 0.1033
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0229 0.0876
Schistosoma mansoni ets-related 0.0021 0.0035 0.0041
Brugia malayi hypothetical protein 0.0148 0.0811 0.2602
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.0229 0.1223
Loa Loa (eye worm) hypothetical protein 0.0451 0.2669 0.8591
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0035 0.0122 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0068 0.0325 0.1033
Mycobacterium ulcerans acyl-CoA synthetase 0.012 0.0643 0.2611
Brugia malayi Nuclear hormone receptor-like 1 0.0068 0.0325 0.1033
Mycobacterium ulcerans hypothetical protein 0.012 0.0643 0.2611
Schistosoma mansoni rotamase 0.0035 0.0119 0.0142
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0451 0.1807
Plasmodium vivax JmjC domain containing protein 0.0029 0.0086 0.0278
Schistosoma mansoni hypothetical protein 0.0322 0.1879 0.224
Brugia malayi nuclear receptor NHR-88 0.0032 0.0103 0.032
Echinococcus granulosus lysine specific demethylase 5A 0.0117 0.0625 0.0729
Entamoeba histolytica serine/threonine protein kinase, putative 0.0197 0.1111 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0627 0.201
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0485
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0164 0.0515
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0409 0.2407 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0086 0.0267
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0325 0.0311
Schistosoma mansoni ran 0.0022 0.0042 0.005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0162 0.0835
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0114 0.0555
Brugia malayi PHD-finger family protein 0.0091 0.0464 0.1481
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0229 0.0876
Brugia malayi tailless protein 0.0032 0.0103 0.032
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0129 0.0695 0.0813
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0068 0.0325 0.1033
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.002 0.0053
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0035 0.002
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0035 0.0122 0.0129
Brugia malayi hypothetical protein 0.0111 0.0583 0.1867
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0058 0.0242
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Schistosoma mansoni hypothetical protein 0.1386 0.8388 1
Brugia malayi Ets-domain containing protein 0.0145 0.0793 0.2542
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0622 0.2586
Echinococcus granulosus cpg binding protein 0.0064 0.03 0.0341
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0035 0.0122 0.0431
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0086 0.0389
Schistosoma mansoni hypothetical protein 0.0021 0.0035 0.0041
Schistosoma mansoni hypothetical protein 0.0042 0.0163 0.0195
Loa Loa (eye worm) spectraplakin 0.0039 0.0142 0.0447
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0054 0.0144
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0247 0.1416 0.1688
Echinococcus granulosus chromobox protein 1 0.0148 0.081 0.095
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0096 0.0322
Echinococcus multilocularis ecdysone induced protein 78C 0.0068 0.0325 0.0311
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Echinococcus multilocularis dna polymerase eta 0.007 0.0334 0.032
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0207 0.0193
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.002 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0127 0.0396
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0504 0.203
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0164 0.0844
Echinococcus multilocularis peregrin 0.01 0.0517 0.0503
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Mycobacterium ulcerans hypothetical protein 0.0157 0.0866 0.3547
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0054 0.004
Loa Loa (eye worm) hypothetical protein 0.0124 0.0664 0.213
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0649 0.0774
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0904 0.1078
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0649 0.2638
Echinococcus multilocularis chromobox protein 1 0.0148 0.081 0.0796
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0325 0.0371
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.0601
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.012 0.0643 0.2611
Brugia malayi Fli-1 protein 0.044 0.2598 0.8363
Schistosoma mansoni hypothetical protein 0.0021 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.012 0.0643 0.2062
Schistosoma mansoni jumonji domain containing protein 0.0237 0.1357 0.1618
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0035 0.0122 0.0431
Plasmodium vivax acyl-CoA synthetase, putative 0.009 0.0457 0.183
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0068 0.0325 0.0371
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0197 0.1111 0.1098
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Schistosoma mansoni kinase 0.01 0.052 0.062
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0126 0.0134
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0028 0.0075 0.0234
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0178 0.0664
Echinococcus granulosus importin subunit beta 1 0.003 0.0091 0.0091
Brugia malayi MH2 domain containing protein 0.0118 0.0627 0.2007
Echinococcus granulosus thyroid hormone receptor alpha 0.0032 0.0103 0.0107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0133 0.0476
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0028 0.0075 0.0061
Schistosoma mansoni fatty acid binding protein 0.0035 0.0118 0.0141
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0102
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.022 0.0915
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0523 0.3106 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0189 0.1061 0.3411
Echinococcus multilocularis microtubule associated protein 2 0.0681 0.4073 0.4064
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.012 0.0643 0.2611
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.009 0.0297
Brugia malayi N-terminal motif family protein 0.0197 0.1112 0.3572
Schistosoma mansoni hypothetical protein 0.1386 0.8388 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Onchocerca volvulus 0.0028 0.0075 0.0082
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0162 0.0835
Brugia malayi SET domain containing protein 0.0025 0.0061 0.0185
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0028 0.0075 0.0327
Echinococcus granulosus jumonji domain containing protein 0.0127 0.0682 0.0798
Plasmodium falciparum phd finger protein, putative 0.0091 0.0464 0.186
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.1061 0.1251
Brugia malayi steroid hormone receptor 0.0068 0.0325 0.1033
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Echinococcus multilocularis cpg binding protein 0.0064 0.03 0.0286
Leishmania major 4-coumarate:coa ligase-like protein 0.012 0.0643 0.3645
Loa Loa (eye worm) hypothetical protein 0.0029 0.0086 0.0267
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Schistosoma mansoni hypothetical protein 0.0039 0.0142 0.0169
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0325 0.0311
Brugia malayi DNA-binding protein D-ETS-3 0.0021 0.0035 0.0098
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0164 0.0844
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0426 0.1704
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0256 0.0815
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.0084 0.01
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0042 0.0094
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0058 0.0226
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.009 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0068 0.0325 0.1033
Leishmania major 4-coumarate:coa ligase-like protein 0.012 0.0643 0.3645
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0164 0.0844
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0126 0.0151
Brugia malayi Bromodomain containing protein 0.016 0.0886 0.2842
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0412 0.1646
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0086 0.0072
Echinococcus multilocularis fatty acid binding protein FABP2 0.0035 0.0118 0.0104
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0068 0.0325 0.0371
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0133 0.0476
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0109 0.0373
Loa Loa (eye worm) hypothetical protein 0.012 0.0643 0.2062
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.022 0.0915
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0431
Leishmania major importin beta-1 subunit, putative 0.0024 0.0056 0.0212
Loa Loa (eye worm) CHromoDomain protein family member 0.0031 0.0098 0.0305
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0035 0.0122 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0068 0.0325 0.1033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Mycobacterium ulcerans acyl-CoA synthetase 0.012 0.0643 0.2611
Onchocerca volvulus 0.0035 0.0122 0.0262
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0032 0.0103 0.0089
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.012 0.0643 0.2611
Mycobacterium ulcerans fatty-acid-CoA ligase 0.012 0.0643 0.2611
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0068 0.0325 0.1033
Echinococcus multilocularis thyroid hormone receptor alpha 0.0068 0.0325 0.0311
Leishmania major mitochondrial DNA polymerase beta 0.0298 0.173 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.009 0.0376
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0068 0.0325 0.0311
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0086 0.0389
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.0229 0.1223
Trypanosoma cruzi kinetoplast DNA-associated protein, putative 0.0039 0.0142 0.0714
Schistosoma mansoni chromobox protein 0.0148 0.081 0.0965
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0299 0.1733 0.2052
Leishmania major DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Leishmania major hypothetical protein, conserved 0.0029 0.0086 0.0389
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0119 0.0375
Echinococcus multilocularis ets variant gene 4 0.0021 0.0035 0.002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.002 0.0006
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0035 0.0122 0.0108
Trypanosoma cruzi ISWI complex protein 0.0031 0.0097 0.0453
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0114 0.0555
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0054 0.0224
Schistosoma mansoni ets 0.0021 0.0035 0.0041
Entamoeba histolytica hypothetical protein 0.0111 0.0583 0.5252
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0028 0.0075 0.0234
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0298 0.173 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0103 0.0107
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0086 0.0072
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.04
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.0164 0.0195
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.0431
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.04
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0164
Echinococcus granulosus chromobox protein 1 0.0148 0.081 0.095
Schistosoma mansoni cpg binding protein 0.0057 0.0256 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Brugia malayi hypothetical protein 0.0036 0.0127 0.0396
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0086 0.0102
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0119 0.0142
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.1879 0.6046
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0053 0.0229 0.1223
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0054 0.0144
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0769 0.4383
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0091 0.0298
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0054 0.0144
Schistosoma mansoni chromobox protein 0.0024 0.0054 0.0064
Brugia malayi jmjC domain containing protein 0.0029 0.0086 0.0264
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0086 0.0072
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0086 0.0072
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.0156 0.0649
Leishmania major 4-coumarate:coa ligase-like protein 0.012 0.0643 0.3645
Loa Loa (eye worm) hypothetical protein 0.0083 0.0412 0.1319
Trichomonas vaginalis rotamase, putative 0.0035 0.0119 0.0419
Echinococcus granulosus fatty acid binding protein FABP2 0.0035 0.0118 0.0124
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.0206
Brugia malayi hypothetical protein 0.0451 0.2669 0.859
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1061 0.1265
Brugia malayi nuclear receptor RXR 0.0032 0.0103 0.032
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.0103 0.0089
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.009 0.0278
Brugia malayi jmjC domain containing protein 0.0117 0.0625 0.2001
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0035 0.0122 0.0601
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Echinococcus granulosus chromobox protein 2 0.0024 0.0054 0.0047
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0036 0.0127 0.0152
Echinococcus multilocularis importin subunit beta 1 0.003 0.0091 0.0077
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0309 0.1797 0.2142
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0028 0.0075 0.0234
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0583 0.0696
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0366 0.2146 0.2559
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0086 0.0102
Echinococcus multilocularis ETS transcription factor Elf 1 0.0021 0.0035 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0451 0.1519
Schistosoma mansoni cpg binding protein 0.0064 0.03 0.0357
Brugia malayi F/Y-rich N-terminus family protein 0.0051 0.0219 0.0692
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0127 0.0396
Echinococcus granulosus geminin 0.1386 0.8388 1
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0028 0.0075 0.0327
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0127 0.0152
Schistosoma mansoni nuclear receptor 0.0032 0.0103 0.0123
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0409 0.2407 1
Echinococcus granulosus Chromobox protein 3 0.0024 0.0054 0.0047
Onchocerca volvulus 0.0065 0.0303 0.0953
Echinococcus multilocularis ewsr:fli fusion protein type 0.0021 0.0035 0.002
Brugia malayi AMP-binding enzyme family protein 0.012 0.0643 0.2059
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0464 0.186
Loa Loa (eye worm) hypothetical protein 0.0036 0.0126 0.0398
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0054 0.0224
Loa Loa (eye worm) retinol dehydrogenase 12 0.0028 0.0075 0.0233
Loa Loa (eye worm) latrophilin receptor protein 2 0.0096 0.0494 0.1582
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0583 0.057
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0649 0.2698
Giardia lamblia DINP protein human, muc B family 0.0042 0.0164 0.1322
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0035 0.0122 0.0431
Schistosoma mansoni hypothetical protein 0.0031 0.0097 0.0116
Entamoeba histolytica hypothetical protein 0.0111 0.0583 0.5252
Brugia malayi Calcitonin receptor-like protein seb-1 0.0304 0.1764 0.5674
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.0229 0.1223
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0042 0.0131
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0028 0.0075 0.0234
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Echinococcus granulosus bloom syndrome protein 0.0044 0.0178 0.0196
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0122 0.0601
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0122 0.0384
Onchocerca volvulus 0.0035 0.0122 0.0262
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.009 0.0091
Loa Loa (eye worm) oxidoreductase 0.0028 0.0075 0.0233
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0144
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0189 0.1061 0.3409
Schistosoma mansoni thyroid hormone receptor 0.0068 0.0325 0.0387
Entamoeba histolytica acyl-CoA synthetase, putative 0.012 0.0643 0.5787
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0028 0.0075 0.0233
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0033 0.011 0.0377
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0096 0.0494 0.0573
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0028 0.0075 0.0234
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.0494 0.048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0068 0.0325 0.1036
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0028 0.0075 0.0234
Loa Loa (eye worm) hypothetical protein 0.0148 0.0811 0.2605
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.1061 0.1049
Brugia malayi Steroid receptor seven-up type 2 0.0068 0.0325 0.1033
Schistosoma mansoni DNA helicase recq1 0.003 0.009 0.0108
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0028 0.0075 0.0313
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0028 0.0075 0.0678
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0178
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0167 0.0618
Leishmania major oxidoreductase-like protein 0.0028 0.0075 0.0327
Schistosoma mansoni bromodomain containing protein 0.0136 0.074 0.0882
Echinococcus granulosus GPCR family 2 0.0096 0.0494 0.0573
Brugia malayi jmjC domain containing protein 0.0299 0.1733 0.5572
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Echinococcus multilocularis tumor protein p63 0.0333 0.1946 0.1935
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0426 0.1704
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0133 0.0476
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0054 0.016
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0035 0.0122 0.0431
Schistosoma mansoni jumonji/arid domain-containing protein 0.0117 0.0625 0.0745
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0086 0.0102
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0031 0.0098 0.0084
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0058 0.0226
Toxoplasma gondii hypothetical protein 0.0048 0.02 0.0831
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0028 0.0075 0.0234
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0133 0.0476
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.0126
Brugia malayi ecdysteroid receptor 0.0068 0.0325 0.1033
Echinococcus granulosus ewsr:fli fusion protein type 0.0021 0.0035 0.0024
Trypanosoma brucei DNA polymerase eta, putative 0.007 0.0334 0.1839
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0144
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.002 0.5
Echinococcus granulosus tumor protein p63 0.0333 0.1946 0.2307
Brugia malayi Ets-domain containing protein 0.0021 0.0035 0.0098
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.022 0.0246
Loa Loa (eye worm) hypothetical protein 0.0049 0.0205 0.065
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.1111 0.6382
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0133 0.0476
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0114 0.0555
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0054 0.016
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0627 0.201
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0164 0.0604
Entamoeba histolytica hypothetical protein 0.0111 0.0583 0.5252
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Trichomonas vaginalis rotamase, putative 0.0034 0.0114 0.0398
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0164 0.0604
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0096 0.0494 0.1579
Loa Loa (eye worm) oxidoreductase 0.0035 0.0122 0.0384
Leishmania major hypothetical protein, conserved 0.0031 0.0097 0.0453
Onchocerca volvulus 0.0451 0.2669 1
Loa Loa (eye worm) nuclear hormone receptor 0.0032 0.0103 0.0324
Loa Loa (eye worm) PHD-finger family protein 0.0091 0.0464 0.1484
Onchocerca volvulus 0.012 0.0643 0.2252
Brugia malayi Protein cec-1. 0.0024 0.0054 0.016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0431
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.04
Echinococcus multilocularis lysine specific demethylase 5A 0.011 0.0581 0.0568
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0431
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0088 0.0367
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0035 0.0122 0.0431
Brugia malayi Bromodomain containing protein 0.0082 0.0408 0.1301
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0283
Echinococcus granulosus snurportin 1 0.0322 0.1879 0.2227
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0229 0.0876
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0028 0.0075 0.0234
Leishmania major DNA polymerase eta, putative 0.007 0.0334 0.1839
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0075 0.0229
Brugia malayi hypothetical protein 0.0025 0.0058 0.0174
Loa Loa (eye worm) hypothetical protein 0.007 0.0334 0.1067
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.0229 0.0215
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0068 0.0325 0.1033
Echinococcus multilocularis nuclear receptor nhr 48 0.0032 0.0103 0.0089
Brugia malayi nuclear receptor NHR-67 0.0032 0.0103 0.032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0649 0.2638
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0036 0.0127 0.0135
Brugia malayi Importin beta-1 subunit 0.003 0.0091 0.0279
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0164 0.0604
Echinococcus granulosus PHD finger protein rhinoceros 0.0091 0.0464 0.0537
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Brugia malayi nuclear receptor NHR-88 0.0068 0.0325 0.1033
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0035 0.0122 0.0431
Schistosoma mansoni ap endonuclease 0.0019 0.002 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.0164 0.015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0068 0.0325 0.0387
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0035 0.0122 0.0431
Onchocerca volvulus 0.0049 0.0205 0.0576
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0028 0.0075 0.0234
Trypanosoma brucei cdc2-related kinase 1 0.0053 0.0229 0.1223
Echinococcus multilocularis PHD finger protein rhinoceros 0.0091 0.0464 0.045
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Loa Loa (eye worm) hypothetical protein 0.0197 0.1112 0.3574
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0109 0.0521
Loa Loa (eye worm) hypothetical protein 0.0068 0.0325 0.1036
Brugia malayi Bromodomain containing protein 0.01 0.0517 0.1653
Brugia malayi AF-10 protein 0.003 0.0088 0.0271
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0201
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.022 0.0841
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.0164 0.1475
Leishmania major DNA polymerase eta, putative 0.0041 0.0156 0.0799
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.002 0.0049
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0086 0.0086
Brugia malayi Muscleblind-like protein 0.0446 0.2633 0.8475
Echinococcus multilocularis chromobox protein 1 0.0148 0.081 0.0796
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0485
Schistosoma mansoni cpg binding protein 0.0064 0.03 0.0357
Trichomonas vaginalis chromobox protein, putative 0.0148 0.081 0.3309
Mycobacterium ulcerans acetyl-CoA synthetase 0.0035 0.0122 0.0431
Echinococcus granulosus protein C ets 2 0.0021 0.0035 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0229 0.0273
Echinococcus multilocularis snurportin 1 0.0322 0.1879 0.1867
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0299 0.1733 0.1721
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0122 0.0431
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0144
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0028 0.0075 0.0234
Brugia malayi hypothetical protein 0.0032 0.0103 0.032
Entamoeba histolytica hypothetical protein 0.0024 0.0056 0.0503
Giardia lamblia Kinase, PLK 0.0197 0.1111 1
Entamoeba histolytica Ran family GTPase 0.0022 0.0042 0.0378
Entamoeba histolytica hypothetical protein 0.0024 0.0054 0.0485
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0058 0.0162
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0068 0.0325 0.0311
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.0103 0.0089
Plasmodium falciparum enoyl-acyl carrier reductase 0.0409 0.2407 1
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0068 0.0325 0.1033
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0068 0.0325 0.0371
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0119 0.0372
Echinococcus multilocularis jumonji domain containing protein 0.0127 0.0682 0.0669
Schistosoma mansoni hypothetical protein 0.0024 0.0054 0.0064
Trypanosoma brucei unspecified product 0.0029 0.0084 0.0376
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.04
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0035 0.0024
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0126 0.0112
Schistosoma mansoni hypothetical protein 0.003 0.0088 0.0105
Schistosoma mansoni hypothetical protein 0.0096 0.0494 0.0589
Loa Loa (eye worm) hypothetical protein 0.0028 0.0075 0.0233
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.0412 0.1371
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0205 0.0244
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.0075 0.0234
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0114 0.103
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0032 0.0103 0.032
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.003 0.0092 0.0305
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0197 0.1111 0.6382
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.022 0.0841
Loa Loa (eye worm) hypothetical protein 0.009 0.0457 0.1462
Brugia malayi serine/threonine-protein kinase plk-2 0.0197 0.1111 0.3568
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1111 0.4571
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.0103 0.0107
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0028 0.0075 0.0327
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.0164 0.0518
Brugia malayi latrophilin 2 splice variant baaae 0.0208 0.1176 0.3778
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.0601
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0068 0.0325 0.1033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0324
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0649 0.2638
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0126 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0164 0.0844
Brugia malayi jmjC domain containing protein 0.0029 0.0086 0.0264
Loa Loa (eye worm) hypothetical protein 0.009 0.0457 0.1462
Mycobacterium ulcerans short chain dehydrogenase 0.0028 0.0075 0.0234
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0053 0.0229 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0054 0.0144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0103 0.0089
Giardia lamblia Kinase, CMGC CDK 0.0053 0.0229 0.1917
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.012 0.0643 0.2611
Leishmania major GTP-binding protein, putative 0.0022 0.0042 0.0131
Brugia malayi VAB-10A protein 0.0039 0.0142 0.0443
Entamoeba histolytica acyl-CoA synthetase, putative 0.012 0.0643 0.5787
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.009 0.0376
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0088 0.0402
Brugia malayi Growth-Arrest-Specific Protein 2 Domain containing protein 0.0039 0.0142 0.0443
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0075 0.0229
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.0164 0.0195
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0028 0.0075 0.0234
Brugia malayi conserved hypotetical protein 0.0032 0.0103 0.032
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0035 0.0122 0.0431
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.0103 0.0107
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0178 0.056
Brugia malayi nuclear hormone receptor 0.0032 0.0103 0.032
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0431
Echinococcus granulosus ETS transcription factor Elf 5 0.0021 0.0035 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0061 0.0073
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0109 0.0977
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0119 0.0142
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0035 0.0122 0.0508
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0054 0.0144
Trypanosoma brucei cdc2-related kinase 3 0.0053 0.0229 0.1223

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) 0 Cytotoxicity against Vero-C1008 cells at 6.25 to 50 ug/ml ChEMBL. 17239490
Activity (ADMET) 0 Cytotoxicity against Vero-C1008 cells at 6.25 to 50 ug/mL by neutral red uptake assay ChEMBL. 17442576
Activity (ADMET) 0 Cytotoxicity against VeroC1008 cells at 6.25 to 50 ug/ml by neutral red uptake assay ChEMBL. 17291769
IC50 (binding) = 390 nM Inhibition of human cdk5/p25 by SPA ChEMBL. 17291769
IC50 (binding) = 390 nM Inhibition of human cdk5/p25 by SPA ChEMBL. 17291769
Inhibition (functional) = 12 % Antibacterial activity against Salmonella typhi at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17239490
Inhibition (functional) = 12 % Antibacterial activity against Salmonella typhi at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17442576
Inhibition (functional) = 14 % Antibacterial activity against Escherichia coli at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17239490
Inhibition (functional) = 14 % Antibacterial activity against Escherichia coli at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17442576
Inhibition (functional) = 14 % Antibacterial activity against Escherichia coli at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17239490
Inhibition (functional) = 14 % Antibacterial activity against Escherichia coli at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17442576
Inhibition (functional) = 17 % Antibacterial activity against Pseudomonas aeruginosa at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17239490
Inhibition (functional) = 17 % Antibacterial activity against Pseudomonas aeruginosa at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17442576
Inhibition (functional) = 18 % Antibacterial activity against Staphylococcus aureus at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17239490
Inhibition (functional) = 18 % Antibacterial activity against Staphylococcus aureus at 50 to 100 uM after 24 hrs by well diffusion method ChEMBL. 17442576
MIC (functional) < 6.25 ug ml-1 Antituberculosis activity against Mycobacterium tuberculosis H37Rv by Microplate Alamar Blue Assay ChEMBL. 17239490
MIC (functional) < 6.25 ug ml-1 Antituberculosis activity against Mycobacterium tuberculosis H37Rv by Microplate Alamar Blue Assay ChEMBL. 17239490
MIC (functional) = 3.13 uM Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay ChEMBL. 17442576
MIC (functional) = 3.13 uM Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay ChEMBL. 17442576

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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