Detailed information for compound 504584

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 344.797 | Formula: C20H13ClN4
  • H donors: 0 H acceptors: 3 LogP: 5.13 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1nn(c2c1c1nc3ccccc3c(c1cn2)Cl)c1ccccc1
  • InChi: 1S/C20H13ClN4/c1-12-17-19-15(18(21)14-9-5-6-10-16(14)23-19)11-22-20(17)25(24-12)13-7-3-2-4-8-13/h2-11H,1H3
  • InChiKey: XCAVHMXVYQXYDY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0038 0.0131
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Brugia malayi hypothetical protein 0.0021 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0012
Echinococcus granulosus heat shock protein 90 0.0086 0.0395 0.1265
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0075 0.033 0.0446
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Entamoeba histolytica hypothetical protein 0.0113 0.0557 0.3077
Echinococcus granulosus ecdysone induced protein 78C 0.0096 0.0458 0.1468
Loa Loa (eye worm) beta-lactamase 0.0075 0.033 0.0446
Schistosoma mansoni neurotransmitter gated ion channel 0.0095 0.0451 0.1447
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0071 0.0392
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0051 0.0184 0.059
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0596 0.0724
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0096 0.0458 0.0619
Loa Loa (eye worm) hypothetical protein 0.0075 0.033 0.0446
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0596 0.309
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.033 0.0401
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0012
Schistosoma mansoni lipoxygenase 0.0022 0.0007 0.0024
Trichomonas vaginalis Clan ME, family M16, insulinase-like metallopeptidase 0.0061 0.0243 0.0856
Brugia malayi Pre-SET motif family protein 0.0062 0.025 0.0338
Plasmodium vivax SET domain protein, putative 0.0062 0.025 0.0818
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0218 0.0767
Schistosoma mansoni loxhd1 0.0022 0.0007 0.0024
Schistosoma mansoni survival motor neuron protein 0.01 0.0479 0.1536
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0004 0.0005
Onchocerca volvulus 0.0075 0.033 0.1164
Brugia malayi Matrixin family protein 0.0067 0.028 0.0379
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0174 0.0961
Loa Loa (eye worm) hypoxia-induced factor 1 0.0165 0.0872 0.1179
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0071 0.037
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0004 0.0012
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0088 0.041 0.0499
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0007 0.0007
Echinococcus multilocularis leucyl aminopeptidase 0.0068 0.0286 0.0286
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0048 0.0166 0.0918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0055 0.0192
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0196 0.1063 0.1437
Loa Loa (eye worm) hypothetical protein 0.0489 0.2829 0.3825
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0339 0.1927 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0012
Trichomonas vaginalis heat shock protein, putative 0.0075 0.0332 0.1172
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0051 0.0184 0.059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.0458 0.1468
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0313 0.0424
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0075 0.0332 0.12
Brugia malayi hypothetical protein 0.0113 0.0557 0.0753
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0101 0.0489 0.1566
Plasmodium falciparum heat shock protein 90 0.0086 0.0395 0.2048
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0114 0.0138
Loa Loa (eye worm) hypothetical protein 0.0062 0.0254 0.0344
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0204 0.0654
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0096 0.0458 0.0619
Schistosoma mansoni hypothetical protein 0.0116 0.0579 0.1856
Loa Loa (eye worm) hypothetical protein 0.0086 0.0399 0.0539
Brugia malayi ecdysteroid receptor 0.0096 0.0458 0.0619
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Plasmodium falciparum falcilysin 0.012 0.0603 0.3127
Loa Loa (eye worm) runx1 0.0061 0.0244 0.033
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0196 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0005
Brugia malayi photoreceptor-specific nuclear receptor 0.0096 0.0458 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0215 0.0757
Echinococcus granulosus jun protein 0.0181 0.097 0.311
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0044 0.0145 0.0753
Onchocerca volvulus Putative endochitinase 0.0082 0.0373 0.1315
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Onchocerca volvulus 0.0096 0.0458 0.1616
Mycobacterium leprae PROBABLE HYDROLASE 0.0081 0.0368 0.1911
Trypanosoma brucei aurora B kinase 0.0056 0.0218 0.0264
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0451 0.061
Giardia lamblia Grp94/Hsp90 0.0075 0.0332 0.1503
Brugia malayi TAR-binding protein 0.0063 0.0255 0.0345
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Loa Loa (eye worm) hypothetical protein 0.0075 0.033 0.0446
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.033 0.1191
Loa Loa (eye worm) steroid hormone receptor 0.0096 0.0458 0.0619
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0007 0.0039
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0313 0.0313
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0151 0.0484
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0056 0.0218 0.1201
Brugia malayi indoleamine 2,3-dioxygenase 0.0537 0.312 0.4219
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.01 0.036
Toxoplasma gondii hypothetical protein 0.0116 0.0579 0.3006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0005
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0138 0.0709 0.0709
Onchocerca volvulus 0.049 0.2835 1
Brugia malayi nuclear receptor NHR-88 0.0096 0.0458 0.0619
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0071 0.037
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.0458 0.1468
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0113 0.0399
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0096 0.0458 0.1468
Toxoplasma gondii ABC1 family protein 0.0075 0.033 0.1712
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0004 0.0012
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0012
Onchocerca volvulus 0.0095 0.0451 0.1592
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.0458 0.0619
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0313 0.1004
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0174 0.0211
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.043 0.2475 0.3347
Echinococcus multilocularis endoplasmin 0.0075 0.0332 0.0332
Onchocerca volvulus 0.0022 0.0007 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0218 0.0697
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0266 0.0852
Loa Loa (eye worm) AUR protein kinase 0.0056 0.0218 0.0294
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0596 0.1909
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Brugia malayi serine/threonine protein kinase 6 0.0056 0.0218 0.0294
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.0821 0.2963
Loa Loa (eye worm) hypothetical protein 0.0051 0.0184 0.0249
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0004 0.0005
Brugia malayi beta-lactamase family protein 0.0075 0.033 0.0446
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0174 0.0558
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0071 0.025
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0196 0.1063 0.3407
Mycobacterium ulcerans chitinase/cellulase 0.0062 0.0254 0.1319
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0151 0.0151
Trypanosoma cruzi heat shock protein 85, putative 0.0086 0.0395 0.048
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0596 0.3291
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0044 0.0227
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0095 0.0451 0.1447
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0101 0.0489 0.0661
Loa Loa (eye worm) hypothetical protein 0.0116 0.0579 0.0783
Toxoplasma gondii leucyl aminopeptidase LAP 0.0339 0.1927 1
Entamoeba histolytica hypothetical protein 0.0026 0.0032 0.0174
Brugia malayi nuclear receptor RXR 0.0051 0.0184 0.0249
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0056 0.0218 0.0713
Trypanosoma cruzi heat shock protein 90, putative 0.0071 0.0307 0.0374
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0196 0.1063 0.1437
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0174 0.0235
Brugia malayi hypoxia-induced factor 1 0.0165 0.0872 0.1179
Loa Loa (eye worm) hypothetical protein 0.0347 0.1974 0.2669
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.001
Giardia lamblia NADPH oxidoreductase, putative 0.0082 0.037 0.172
Brugia malayi hypothetical protein 0.0134 0.0687 0.0929
Leishmania major hypothetical protein, conserved 0.0075 0.033 0.0401
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0055 0.0075
Echinococcus granulosus glycine receptor subunit beta 0.0196 0.1063 0.3407
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0048 0.0166 0.0166
Trypanosoma cruzi heat shock protein 85, putative 0.0086 0.0395 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Echinococcus granulosus dual specificity 0.0088 0.041 0.1316
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0004 0.0012
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.033 0.1191
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.01 0.0121
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0278 0.0892
Leishmania major hypothetical protein, conserved 0.0028 0.0044 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0037 0.013
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.033 0.1163
Plasmodium falciparum conserved protein, unknown function 0.0116 0.0579 0.3006
Brugia malayi hypothetical protein 0.0133 0.0682 0.0922
Onchocerca volvulus 0.0067 0.028 0.0989
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0113 0.0399
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0096 0.0458 0.1468
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0004 0.0012
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0044 0.0145 0.0196
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Brugia malayi Matrixin family protein 0.0067 0.028 0.0379
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0278 0.0892
Onchocerca volvulus 0.0095 0.0449 0.1584
Echinococcus multilocularis glycine receptor subunit beta 0.0196 0.1063 0.1063
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0075 0.0332 0.0404
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0596 0.215
Giardia lamblia NADPH oxidoreductase, putative 0.0082 0.037 0.172
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0101 0.0489 0.0661
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.1382 0.8224 1
Schistosoma mansoni hypothetical protein 0.0023 0.0014 0.0043
Onchocerca volvulus 0.0075 0.033 0.1164
Brugia malayi nuclear receptor NHR-67 0.0045 0.0151 0.0204
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0012
Trypanosoma brucei heat shock protein 90, putative 0.0086 0.0395 0.0479
Schistosoma mansoni RAR-like nuclear receptor 0.0096 0.0458 0.1468
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0045 0.0151 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Loa Loa (eye worm) matrix metalloproteinase 0.0067 0.028 0.0379
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0196 0.1063 0.3407
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.007
Brugia malayi ecdysone receptor 0.0045 0.0151 0.0204
Schistosoma mansoni hypothetical protein 0.0518 0.3004 0.9626
Brugia malayi RNA binding protein 0.0063 0.0255 0.0345
Trichomonas vaginalis heat shock protein, putative 0.0075 0.0332 0.1172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0151 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Loa Loa (eye worm) hypothetical protein 0.0142 0.0733 0.0991
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0088 0.041 0.0499
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0196 0.1063 0.3407
Schistosoma mansoni lamin 0.003 0.0055 0.0177
Onchocerca volvulus 0.0116 0.0579 0.2043
Brugia malayi PAS domain containing protein 0.0053 0.0199 0.0269
Onchocerca volvulus 0.0196 0.1063 0.375
Echinococcus multilocularis geminin 0.0518 0.3004 0.3004
Entamoeba histolytica hypothetical protein 0.0113 0.0557 0.3077
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0098 0.0509
Schistosoma mansoni zinc finger protein 0.0045 0.0151 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0116 0.0579 0.1897
Echinococcus granulosus RUN 0.0022 0.0007 0.0024
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0004 0.0012
Toxoplasma gondii TIM10 family protein, putative 0.0052 0.0193 0.1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.033 0.1057
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.01 0.0351
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0096 0.0458 0.1468
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0596 0.3291
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.025 0.025
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0255 0.0345
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.01 0.0121
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Brugia malayi steroid hormone receptor 0.0096 0.0458 0.0619
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.033 0.0446
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0218 0.1201
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.01 0.0518
Mycobacterium ulcerans hydrolase 0.0081 0.0368 0.1911
Loa Loa (eye worm) hypothetical protein 0.0054 0.0204 0.0276
Plasmodium falciparum endoplasmin, putative 0.0058 0.0229 0.1187
Onchocerca volvulus 0.0196 0.1063 0.375
Brugia malayi Nuclear hormone receptor-like 1 0.0096 0.0458 0.0619
Echinococcus multilocularis glycine receptor subunit beta 0.0196 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0176 0.094 0.1271
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0313 0.0424
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Onchocerca volvulus Protein ultraspiracle homolog 0.0096 0.0458 0.1616
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0196 0.1063 0.1437
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0313 0.0381
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0196 0.1063 0.3407
Schistosoma mansoni neurotransmitter gated ion channel 0.0101 0.0489 0.1566
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0793 0.4666 0.6309
Trypanosoma cruzi pitrilysin-like metalloprotease, putative 0.012 0.0603 0.0733
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0196 0.1063 0.3407
Giardia lamblia GTOR 0.0049 0.0174 0.0592
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0096 0.0458 0.0619
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Plasmodium falciparum serine/threonine protein kinase, putative 0.0056 0.0218 0.1129
Loa Loa (eye worm) hypothetical protein 0.1245 0.7396 1
Brugia malayi nuclear hormone receptor 0.0096 0.0458 0.0619
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0313 0.0381
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0068 0.0286 0.0386
Brugia malayi hypothetical protein 0.0095 0.0451 0.061
Trypanosoma brucei heat shock protein 84, putative 0.0048 0.0166 0.0202
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0032 0.0164
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0313 0.0381
Brugia malayi hypothetical protein 0.0028 0.0044 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0596 0.21
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0096 0.0458 0.0458
Trichomonas vaginalis Clan ME, family M16, insulinase-like metallopeptidase 0.012 0.0603 0.2126
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0255 0.0345
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0071 0.0233
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0151 0.0533
Chlamydia trachomatis cytosol aminopeptidase 0.0339 0.1927 1
Echinococcus multilocularis FTZ F1 alpha 0.0096 0.0458 0.0458
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Schistosoma mansoni nAChR subunit 0.0095 0.0451 0.1447
Schistosoma mansoni lipoxygenase 0.006 0.0242 0.0776
Brugia malayi phosphofructokinase 0.0119 0.0596 0.0805
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0044 0.0053
Brugia malayi conserved hypotetical protein 0.0045 0.0151 0.0204
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0004 0.0004
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0151 0.0151
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.0821 0.4259
Echinococcus granulosus glycine receptor subunit alpha 1 0.0196 0.1063 0.3407
Schistosoma mansoni hypothetical protein 0.0095 0.0449 0.1439
Loa Loa (eye worm) hypothetical protein 0.0044 0.0145 0.0196
Mycobacterium ulcerans chitinase/cellulase 0.0062 0.0254 0.1319
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0113 0.0399
Echinococcus granulosus glycine receptor subunit alpha 1 0.0196 0.1063 0.3407
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.0821 0.4259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0114 0.0138
Echinococcus multilocularis leucyl aminopeptidase 0.0068 0.0286 0.0286
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0044 0.0145 0.0196
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0479 0.277 1
Brugia malayi hypothetical protein 0.0095 0.0451 0.061
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0007 0.0024
Loa Loa (eye worm) RNA binding protein 0.0063 0.0255 0.0345
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0044 0.0227
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0427 0.1367
Onchocerca volvulus 0.0039 0.0115 0.0406
Echinococcus granulosus nAChR subunit 0.0101 0.0489 0.1566
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.1809 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0005
Onchocerca volvulus Huntingtin homolog 0.0134 0.0687 0.2423
Loa Loa (eye worm) matrixin family protein 0.0161 0.0852 0.1152
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0255 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0038 0.0131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0096 0.0458 0.0619
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0016 0.005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0096 0.0458 0.0458
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0096 0.0458 0.1468
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0016 0.005
Loa Loa (eye worm) endoplasmin 0.0086 0.0395 0.0534
Echinococcus granulosus tar DNA binding protein 0.0063 0.0255 0.0818
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0045 0.0151 0.0483
Onchocerca volvulus 0.0062 0.025 0.0881
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.033 0.1057
Echinococcus granulosus histone lysine methyltransferase setb 0.008 0.0363 0.1162
Brugia malayi small heat shock protein 0.1245 0.7396 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Echinococcus granulosus geminin 0.0518 0.3004 0.9626
Trypanosoma brucei Heat shock protein 83, putative 0.0086 0.0395 0.0479
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0116 0.0579 0.1856
Brugia malayi Matrixin family protein 0.0067 0.028 0.0379
Echinococcus multilocularis tumor protein p63 0.037 0.211 0.211
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0196 0.1063 0.3407
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0181 0.097 0.311
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0151 0.0533
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0266 0.0852
Onchocerca volvulus Matrilysin homolog 0.0148 0.0772 0.2722
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0051 0.0184 0.0184
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0115 0.0367
Plasmodium vivax heat shock protein, putative 0.0205 0.1113 0.3645
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0071 0.0307 0.0985
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.01 0.036
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0052 0.0193 0.1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0479 0.0648
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0091 0.0427 0.0577
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0196 0.1063 0.1063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Echinococcus multilocularis jun protein 0.0181 0.097 0.097
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0096 0.0458 0.0619
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0151 0.0484
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0068 0.0286 0.0386
Onchocerca volvulus 0.01 0.0479 0.1691
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0278 0.0377
Schistosoma mansoni retinoic acid receptor RXR 0.0204 0.111 0.3556
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0218 0.0767
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0427 0.1367
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0095 0.0451 0.0451
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.033 0.0401
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0196 0.1063 0.3407
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0056 0.0218 0.0218
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0048 0.0166 0.0587
Echinococcus multilocularis lamin 0.003 0.0055 0.0055
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0071 0.037
Echinococcus granulosus FTZ F1 alpha 0.0096 0.0458 0.1468
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0038 0.0131
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0557 0.1785
Loa Loa (eye worm) hypothetical protein 0.0179 0.0956 0.1292
Schistosoma mansoni heat shock protein 0.0086 0.0395 0.1265
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0207 0.0279
Echinococcus granulosus leucyl aminopeptidase 0.0068 0.0286 0.0916
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.002
Schistosoma mansoni hypothetical protein 0.0022 0.0007 0.0024
Trichomonas vaginalis esterase, putative 0.0075 0.033 0.1163
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0032 0.0164
Brugia malayi hypothetical protein 0.0022 0.0007 0.001
Mycobacterium ulcerans leucyl aminopeptidase 0.0339 0.1927 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0032 0.0039
Echinococcus granulosus survival motor neuron protein 1 0.0489 0.2829 0.9067
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0596 0.0805
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0096 0.0458 0.0619
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0088 0.041 0.0499
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0096 0.0458 0.0619
Onchocerca volvulus 0.0054 0.0204 0.072
Echinococcus multilocularis heat shock protein 90 0.0071 0.0307 0.0307
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0007 0.001
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.1382 0.8224 1
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0068 0.0286 0.0916
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0096 0.0458 0.0619
Echinococcus multilocularis aurora kinase A 0.0056 0.0218 0.0218
Loa Loa (eye worm) AUR protein kinase 0.0056 0.0218 0.0294
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0082 0.037 0.1305
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.0458 0.0619
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0151 0.0204
Brugia malayi hypothetical protein 0.0095 0.0451 0.061
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0004 0.0012
Echinococcus granulosus heat shock protein 90 0.0071 0.0307 0.0985
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.013 0.013
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0007 0.0024
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0115 0.0156
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0068 0.0286 0.0386
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0278 0.0892
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0174 0.0212
Brugia malayi Doublecortin family protein 0.0022 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Trypanosoma cruzi Heat shock protein 83, putative 0.0086 0.0395 0.048
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0116 0.0579 0.0579
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.033 0.1191
Schistosoma mansoni nuclear receptor 0.0045 0.0151 0.0484
Loa Loa (eye worm) GABA receptor subunit 0.0101 0.0489 0.0661
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.025 0.0801
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0044 0.0053
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.01 0.01
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0255 0.0818
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0269 0.1499 0.5411
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0218 0.0767
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.008 0.0363 0.0363
Plasmodium falciparum M17 leucyl aminopeptidase 0.0339 0.1927 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0053 0.0185
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.002
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0101 0.0489 0.0661
Treponema pallidum heat shock protein 90 0.0075 0.0332 0.1692
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0196 0.1063 0.3407
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0596 0.0724
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0261 0.1455 0.1967
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Brugia malayi Muscleblind-like protein 0.0311 0.1756 0.2374
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0255 0.0818
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0335 0.1899 0.2567
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.033 0.1163
Echinococcus multilocularis heat shock protein 0.0086 0.0395 0.0395
Brugia malayi Hsp90 protein 0.0048 0.0166 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0131 0.046
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0044 0.0145 0.0145
Echinococcus multilocularis heat shock protein 90 0.0086 0.0395 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0339 0.1927 0.2343
Schistosoma mansoni polycystin 1-related 0.0022 0.0007 0.0024
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0026 0.0084
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Mycobacterium ulcerans heat shock protein 90 0.0075 0.0332 0.1725
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0247 0.087
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0196 0.1063 0.1063
Echinococcus granulosus lamin 0.003 0.0055 0.0177
Plasmodium vivax heat shock protein 90, putative 0.0048 0.0166 0.0545
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Trypanosoma brucei heat shock protein 90, putative 0.0086 0.0395 0.0479
Loa Loa (eye worm) hypothetical protein 0.0047 0.0159 0.0215
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0115 0.0597
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0174 0.0613
Onchocerca volvulus 0.0116 0.0579 0.2043
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0196 0.1063 0.1063
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0184 0.0249
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0218 0.0767
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0196 0.1063 0.3407
Echinococcus granulosus endoplasmin 0.0075 0.0332 0.1065
Schistosoma mansoni hypothetical protein 0.0113 0.0557 0.1785
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0026 0.0084
Trypanosoma cruzi heat shock protein 90, putative 0.0086 0.0395 0.048
Giardia lamblia Heat shock protein HSP 90-alpha 0.0071 0.0307 0.1359
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0313 0.0381
Mycobacterium ulcerans beta-lactamase 0.0075 0.033 0.1712
Brugia malayi Hemopexin family protein 0.0095 0.0449 0.0607
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0114 0.0138
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0004 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0363 0.1162
Onchocerca volvulus Putative endochitinase 0.0082 0.0373 0.1315
Onchocerca volvulus 0.0095 0.0451 0.1592
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0102 0.0138
Echinococcus granulosus zinc finger protein 0.0021 0.0007 0.0021
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0157 0.0822 0.1112
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0052 0.0193 0.0618
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0272 0.0272
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0666 0.0901
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0016 0.0021
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0151 0.0484
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0289 0.1622 0.8414
Brugia malayi hypothetical protein 0.0095 0.0451 0.061
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0004 0.0012
Mycobacterium tuberculosis Possible chitinase 0.0062 0.0254 0.0918
Trichomonas vaginalis endoplasmin, putative 0.0058 0.0229 0.0806
Loa Loa (eye worm) hypothetical protein 0.0045 0.0146 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0174 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0012
Echinococcus granulosus leucine aminopeptidase protein 0.0339 0.1927 0.6176
Onchocerca volvulus 0.0142 0.0736 0.2595
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0196 0.1063 0.1437
Schistosoma mansoni hypothetical protein 0.0537 0.312 1
Echinococcus granulosus heat shock protein 0.0086 0.0395 0.1265
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0196 0.1063 0.1437
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0427 0.0427
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0596 0.0596
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0082 0.037 0.1305
Loa Loa (eye worm) hypothetical protein 0.0051 0.0184 0.0249
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0151 0.0484
Onchocerca volvulus 0.0022 0.0007 0.0026
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0537 0.312 0.312
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0199 0.0637
Echinococcus granulosus nAChR subunit 0.0196 0.1063 0.3407
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0096 0.0458 0.1616
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0151 0.0204
Echinococcus multilocularis nAChR subunit 0.0101 0.0489 0.0489
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0196 0.1063 0.1437
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0004 0.0004
Giardia lamblia Heat shock protein HSP 90-alpha 0.0086 0.0395 0.1862
Loa Loa (eye worm) hypothetical protein 0.0575 0.335 0.453
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0596 0.0724
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0081 0.0368 0.133
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0096 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.002
Loa Loa (eye worm) cuticular endochitinase 0.0073 0.0319 0.0432
Entamoeba histolytica protein kinase, putative 0.0056 0.0218 0.1201
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Entamoeba histolytica protein kinase, putative 0.0056 0.0218 0.1201
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Schistosoma mansoni hypothetical protein 0.0138 0.0709 0.2273
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0071 0.025
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0196 0.1063 0.1437
Echinococcus multilocularis leucyl aminopeptidase 0.0068 0.0286 0.0286
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0115 0.0115
Treponema pallidum fructose-bisphosphate aldolase 0.032 0.1809 1
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.033 0.1163
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.0458 0.0619
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0526 0.3053 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Echinococcus multilocularis expressed protein 0.0052 0.0193 0.0193
Leishmania major pitrilysin-like metalloprotease,metallo-peptidase, Clan ME, Family M16C 0.012 0.0603 0.0733
Entamoeba histolytica protein kinase , putative 0.0056 0.0218 0.1201
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Brugia malayi serine/threonine-protein kinase 6 0.0056 0.0218 0.0294
Loa Loa (eye worm) hypothetical protein 0.008 0.0363 0.049
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0289 0.1622 0.8414
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0075 0.0332 0.1725
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0196 0.1063 0.1437
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Schistosoma mansoni single-minded 0.0053 0.0199 0.0637
Schistosoma mansoni coup transcription factor 0.0096 0.0458 0.1468
Onchocerca volvulus 0.0095 0.0451 0.1592
Brugia malayi heat shock protein 90 0.0086 0.0395 0.0534
Onchocerca volvulus 0.0045 0.0151 0.0533
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0052 0.0193 0.0261
Entamoeba histolytica protein kinase domain containing protein 0.0088 0.041 0.2268
Plasmodium vivax endoplasmin, putative 0.0086 0.0395 0.1293
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0255 0.0818
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0151 0.0151
Onchocerca volvulus 0.0101 0.0489 0.1724
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.033 0.1163
Loa Loa (eye worm) hypothetical protein 0.0075 0.033 0.0446
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0096 0.0458 0.0619
Brugia malayi Endoplasmin precursor 0.0086 0.0395 0.0534
Loa Loa (eye worm) hypothetical protein 0.0081 0.0368 0.0498
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0052 0.0193 0.0631
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.01 0.0384
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0151 0.0484
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0044 0.0145 0.0196
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0096 0.0458 0.1468
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0266 0.0266
Schistosoma mansoni eupitrilysin (M16 family) 0.012 0.0603 0.1932
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0196 0.1063 0.1063
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.033 0.1191
Schistosoma mansoni hypothetical protein 0.0518 0.3004 0.9626
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0044 0.0227
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Loa Loa (eye worm) hypothetical protein 0.0075 0.033 0.0446
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0157 0.0822 0.1112
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0075 0.0332 0.1587
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.033 0.1191
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0151 0.0484
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0095 0.0451 0.0451
Echinococcus granulosus aurora kinase A 0.0056 0.0218 0.0697
Brugia malayi hypothetical protein 0.0051 0.0184 0.0249
Leishmania major heat shock protein, putative 0.0048 0.0166 0.0202
Brugia malayi nuclear hormone receptor 0.0045 0.0151 0.0204
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.1382 0.8224 1
Schistosoma mansoni nuclear receptor 0.0045 0.0151 0.0484
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0196 0.1063 0.1437
Brugia malayi hypothetical protein 0.0095 0.0451 0.061
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0032 0.0038
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0048 0.0166 0.0533
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0032 0.0164
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0032 0.0104
Loa Loa (eye worm) microfilarial chitinase 0.0071 0.0308 0.0416
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0088 0.041 0.0555
Loa Loa (eye worm) hypothetical protein 0.0067 0.028 0.0379
Schistosoma mansoni heat shock protein 0.0048 0.0166 0.0533
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0141 0.0497
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0313 0.1004
Trypanosoma brucei pitrilysin-like metalloprotease 0.012 0.0603 0.0732
Schistosoma mansoni zinc finger protein 0.0021 0.0007 0.0021
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0196 0.1063 0.1437
Brugia malayi Matrixin family protein 0.0161 0.0852 0.1152
Echinococcus multilocularis RUN 0.0022 0.0007 0.0007
Entamoeba histolytica heat shock protein 90, putative 0.0086 0.0395 0.2181
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0272 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0055 0.0192
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0196 0.1063 0.1063
Mycobacterium ulcerans hypothetical protein 0.0075 0.033 0.1712
Trypanosoma cruzi aurora B kinase, putative 0.0056 0.0218 0.0265
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.033 0.1712
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0181 0.097 0.097
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0184 0.0249
Brugia malayi hypothetical protein 0.0051 0.0184 0.0249
Plasmodium vivax heat shock protein 86, putative 0.0086 0.0395 0.1293
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.0458 0.0619
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0196 0.1063 0.1437
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0339 0.1927 1
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.0364 0.1166
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0196 0.1063 0.3407
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0067 0.028 0.0899
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0151 0.0484
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0236 0.0757
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0196 0.1063 0.3407
Loa Loa (eye worm) ACC-1 protein 0.0196 0.1063 0.1437
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0056 0.0218 0.1201
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0012
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0196 0.1063 0.1063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0055 0.0192
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0427 0.0577
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0071 0.025
Echinococcus granulosus presequence protease mitochondrial 0.0118 0.0592 0.1897
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0157 0.0822 0.2636
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.0458 0.0458
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0151 0.0204
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.01 0.0518
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0096 0.0458 0.0619
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0096 0.0458 0.1468
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.033 0.1163
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0339 0.1927 0.2343
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0204 0.111 0.3556
Entamoeba histolytica protein kinase, putative 0.0088 0.041 0.2268
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0196 0.1063 0.3407
Brugia malayi 6-phosphofructokinase 0.0119 0.0596 0.0805
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0151 0.0204
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0174 0.0212
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0096 0.0458 0.1468
Brugia malayi endochitinase 0.0073 0.0319 0.0432
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0081 0.0368 0.0498
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0044 0.0145 0.0753
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0174 0.0613
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Brugia malayi hypothetical protein 0.004 0.0119 0.0161
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0014 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.041 0.1316
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Brugia malayi endochitinase 0.0082 0.0373 0.0504
Trichomonas vaginalis Clan ME, family M16, insulinase-like metallopeptidase 0.0061 0.0243 0.0856
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.01 0.0135
Entamoeba histolytica Zn-dependent peptidase, putative 0.0118 0.0592 0.3271
Onchocerca volvulus 0.0101 0.0489 0.1724
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0596 0.0805
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0005
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Schistosoma mansoni rab6-interacting 0.0022 0.0007 0.0024
Echinococcus granulosus intermediate filament protein 0.003 0.0055 0.0177
Onchocerca volvulus Matrilysin homolog 0.0067 0.028 0.0989
Trichomonas vaginalis heat shock protein, putative 0.0058 0.0229 0.0806
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0174 0.0212
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0044 0.0145 0.0475
Schistosoma mansoni lamin 0.003 0.0055 0.0177
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.01 0.055
Trypanosoma brucei aminopeptidase, putative 0.0068 0.0286 0.0347
Brugia malayi Cation transporter family protein 0.0196 0.1063 0.1437
Echinococcus multilocularis muscleblind protein 1 0.0311 0.1756 0.1756
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0339 0.1927 0.2343
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0266 0.0266
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0004 0.0012
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0018 0.0021
Schistosoma mansoni lozenge 0.0061 0.0244 0.0783
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0596 0.0805
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0096 0.0458 0.1468
Echinococcus granulosus muscleblind protein 0.0311 0.1756 0.5627
Entamoeba histolytica hypothetical protein 0.0101 0.0489 0.2701
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.033 0.1191
Echinococcus multilocularis presequence protease, mitochondrial 0.0118 0.0592 0.0592
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0052 0.0193 0.0261
Giardia lamblia Metalloprotease, insulinase family 0.0116 0.0575 0.2897
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0071 0.037
Schistosoma mansoni neurotransmitter gated ion channel 0.0095 0.0451 0.1447
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0174 0.0961
Plasmodium vivax hypothetical protein, conserved 0.0075 0.033 0.1081
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0115 0.0115
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0196 0.1063 0.1437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0053 0.0185
Brugia malayi hypothetical protein 0.0045 0.0151 0.0204
Toxoplasma gondii heat shock protein 90, putative 0.0086 0.0395 0.2048
Brugia malayi Pre-SET motif family protein 0.043 0.2475 0.3347
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0537 0.312 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Loa Loa (eye worm) hypothetical protein 0.0134 0.0687 0.0929
Echinococcus granulosus glycine receptor subunit alpha 1 0.0196 0.1063 0.3407
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.025 0.1296
Echinococcus granulosus glycine receptor subunit beta 0.0196 0.1063 0.3407
Echinococcus multilocularis lamin dm0 0.003 0.0055 0.0055
Toxoplasma gondii peptidase M16 inactive domain-containing protein 0.0118 0.0592 0.3071
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.025 0.0801
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0071 0.037
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0666 0.0901
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0196 0.1063 0.1437
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0196 0.1063 0.1063
Toxoplasma gondii aurora kinase 0.0056 0.0218 0.1129
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0196 0.1063 0.1437
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0596 0.21
Brugia malayi 6-phosphofructokinase 0.0119 0.0596 0.0805
Schistosoma mansoni nAChR subunit 0.0095 0.0451 0.1447
Echinococcus granulosus transcription factor Dp 1 0.0042 0.013 0.0416
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0151 0.0151
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0255 0.0818
Schistosoma mansoni leucine aminopeptidase 0.0068 0.0286 0.0916
Mycobacterium ulcerans lipase LipD 0.0075 0.033 0.1712
Schistosoma mansoni nuclear hormone receptor 0.0096 0.0458 0.1468
Echinococcus granulosus single minded 2 0.0039 0.0115 0.0369
Onchocerca volvulus Huntingtin homolog 0.0134 0.0687 0.2423
Schistosoma mansoni hypothetical protein 0.0037 0.0102 0.0328
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.1382 0.8224 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Brugia malayi MH2 domain containing protein 0.0131 0.0666 0.0901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0098 0.0345
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0174 0.0174
Brugia malayi hypothetical protein 0.0485 0.2804 0.3792
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0004 0.0004
Brugia malayi Endochitinase 0.0082 0.0373 0.0504
Mycobacterium tuberculosis Conserved protein 0.0075 0.033 0.1191
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0255 0.0345
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0068 0.0286 0.0916
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0196 0.1063 0.1437
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0151 0.0204
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0032 0.0164
Giardia lamblia Metalloprotease, insulinase family 0.012 0.0603 0.3059
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0096 0.0458 0.0458
Onchocerca volvulus Putative nachr subunit 0.0196 0.1063 0.375
Echinococcus multilocularis ecdysone induced protein 78C 0.0096 0.0458 0.0458
Schistosoma mansoni rab6-interacting 0.0022 0.0007 0.0024
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0101 0.0489 0.1566
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Brugia malayi Bromodomain containing protein 0.0042 0.013 0.0176
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0596 0.21
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.01 0.0327
Loa Loa (eye worm) hypothetical protein 0.0077 0.0345 0.0466
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Toxoplasma gondii exonuclease III APE 0.0037 0.01 0.0518
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0196 0.1063 0.1063
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0004 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Giardia lamblia Aurora kinase 0.0056 0.0218 0.0842
Echinococcus multilocularis expressed protein 0.0408 0.2344 0.2344
Brugia malayi nuclear receptor NHR-88 0.0045 0.0151 0.0204
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0131 0.0159
Toxoplasma gondii heat shock protein HSP90 0.0086 0.0395 0.2048
Trichomonas vaginalis Clan ME, family M16, insulinase-like metallopeptidase 0.012 0.0603 0.2126
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0557 0.0557
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0071 0.037
Schistosoma mansoni endoplasmin 0.0086 0.0395 0.1265
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0196 0.1063 0.1437
Mycobacterium tuberculosis Conserved protein 0.0075 0.033 0.1191
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Leishmania major chitinase 0.0073 0.0319 0.0388
Brugia malayi intermediate filament protein 0.003 0.0055 0.0075
Echinococcus granulosus leucyl aminopeptidase 0.0068 0.0286 0.0916
Loa Loa (eye worm) acetylcholine receptor protein 0.0095 0.0451 0.061
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.067 0.3925 0.5306
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0122 0.0614 0.1969
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0096 0.0458 0.1468
Trichomonas vaginalis Clan ME, family M16, insulinase-like metallopeptidase 0.012 0.0603 0.2126
Loa Loa (eye worm) heat shock protein 75 0.0048 0.0166 0.0225
Brugia malayi Matrixin family protein 0.0067 0.028 0.0379
Schistosoma mansoni hypothetical protein 0.0044 0.0145 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0096 0.0458 0.0619
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0307 0.0374
Brugia malayi Protein kinase domain containing protein 0.0088 0.041 0.0555
Mycobacterium leprae Probable lipase LipE 0.0075 0.033 0.1712
Loa Loa (eye worm) hypothetical protein 0.0485 0.2804 0.3792
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.033 0.0401
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0101 0.0489 0.0661
Loa Loa (eye worm) hypothetical protein 0.0096 0.0458 0.0619
Brugia malayi follicle stimulating hormone receptor 0.0261 0.1455 0.1967
Entamoeba histolytica chitinase, putative 0.0073 0.0319 0.1764
Trichomonas vaginalis heat shock protein, putative 0.0086 0.0395 0.1392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0242 0.0242
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0004 0.0012
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0151 0.0204
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.01 0.0165
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Onchocerca volvulus 0.003 0.0055 0.0195
Loa Loa (eye worm) hypothetical protein 0.0051 0.0184 0.0249
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0151 0.0484
Echinococcus multilocularis Protein lozenge 0.0061 0.0244 0.0244
Echinococcus multilocularis survival motor neuron protein 1 0.0489 0.2829 0.2829
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0032 0.0164
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0032 0.0114
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Trichomonas vaginalis Clan ME, family M16, insulinase-like metallopeptidase 0.012 0.0603 0.2126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0113 0.0399
Onchocerca volvulus 0.0485 0.2804 0.9892
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0174 0.0558
Schistosoma mansoni protein kinase 0.0056 0.0218 0.0697
Loa Loa (eye worm) hypothetical protein 0.0311 0.1756 0.2374
Loa Loa (eye worm) DR-78 0.0045 0.0151 0.0204
Brugia malayi PXA domain containing protein 0.0021 0.0004 0.0005
Brugia malayi excitatory GABA receptor EXP-1A 0.0196 0.1063 0.1437
Loa Loa (eye worm) hypothetical protein 0.0071 0.0305 0.0412
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0174 0.0211
Schistosoma mansoni bromodomain containing protein 0.0069 0.0295 0.0947
Brugia malayi hypothetical protein 0.0045 0.0151 0.0204
Echinococcus multilocularis leucine aminopeptidase protein 0.0339 0.1927 0.1927
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0056 0.0218 0.1201
Onchocerca volvulus Putative endochitinase 0.0073 0.0319 0.1127
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.01 0.0135
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0313 0.1731
Schistosoma mansoni heat shock protein 0.0086 0.0395 0.1265
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0596 0.1909
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0151 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0096 0.0458 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0038 0.0131
Loa Loa (eye worm) LGC-31 protein 0.0196 0.1063 0.1437
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0596 0.21
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.0458 0.0619
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0138 0.0709 0.2273
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0196 0.1063 0.3407
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0184 0.059
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0537 0.312 0.4219
Brugia malayi hypothetical protein 0.0489 0.2829 0.3825
Entamoeba histolytica protein kinase, putative 0.0088 0.041 0.2268
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0071 0.0233
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0088 0.041 0.0499
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0051 0.0184 0.0249
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0596 0.3291
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.033 0.0446
Echinococcus granulosus tumor protein p63 0.037 0.211 0.6763
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0116 0.0579 0.0783
Trypanosoma cruzi heat shock protein 85, putative 0.0086 0.0395 0.048
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Loa Loa (eye worm) hypothetical protein 0.0051 0.0184 0.0249
Onchocerca volvulus Putative endochitinase 0.0082 0.0373 0.1315
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Entamoeba histolytica heat shock protein 90, putative 0.0086 0.0395 0.2181
Onchocerca volvulus 0.0196 0.1063 0.375
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0007 0.0024
Echinococcus multilocularis musashi 0.003 0.0055 0.0055
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0004 0.0005
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0095 0.0451 0.061
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0243 0.1343 0.4305
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0207 0.0279
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0537 0.312 1
Schistosoma mansoni nAChR subunit 0.0196 0.1063 0.3407
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0174 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0016 0.005
Loa Loa (eye worm) AUR protein kinase 0.0056 0.0218 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0071 0.025
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0055 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0067 0.028 0.0379
Schistosoma mansoni hypothetical protein 0.0057 0.0219 0.0702
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0095 0.0451 0.061
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.033 0.1712
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0174 0.0235
Schistosoma mansoni ap endonuclease 0.0037 0.01 0.032
Mycobacterium tuberculosis Conserved protein 0.0075 0.033 0.1191
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0056 0.0218 0.0697
Loa Loa (eye worm) matrixin family protein 0.0148 0.0772 0.1043
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.01 0.0121
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Toxoplasma gondii Hsp90 domain-containing protein 0.0205 0.1113 0.5774
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0242 0.0776
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0004 0.0012
Brugia malayi jmjC domain containing protein 0.0064 0.0266 0.0359
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0451 0.061
Schistosoma mansoni acetylcholine receptor-related 0.0095 0.0451 0.1447
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Brugia malayi Steroid receptor seven-up type 2 0.0096 0.0458 0.0619
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0071 0.0222
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0196 0.1063 0.1437
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0095 0.0451 0.1447
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0596 0.3173
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0082 0.037 0.1305
Schistosoma mansoni intermediate filament proteins 0.003 0.0055 0.0177
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.01 0.0351
Brugia malayi hypothetical protein 0.0022 0.0007 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0822 0.2636
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0032 0.0164
Brugia malayi tailless protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) heat shock protein 90 0.0086 0.0395 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.0458 0.0619
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0339 0.1927 0.2343
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0157 0.0822 0.1112
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0095 0.0451 0.061
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Echinococcus multilocularis muscleblind protein 0.0311 0.1756 0.1756
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0196 0.1063 0.1437
Onchocerca volvulus Bile acid receptor homolog 0.0096 0.0458 0.1616
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0157 0.0822 0.1112
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0028 0.0048 0.025
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0016 0.0021
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0071 0.025
Brugia malayi serine/threonine kinase 12 0.0056 0.0218 0.0294
Loa Loa (eye worm) hypothetical protein 0.0116 0.0579 0.0783
Schistosoma mansoni jun-related protein 0.0147 0.0766 0.2453
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.001
Brugia malayi Cation transporter family protein 0.0196 0.1063 0.1437
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0004 0.0005
Loa Loa (eye worm) intermediate filament protein 0.003 0.0055 0.0075
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0157 0.0822 0.2901
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0339 0.1927 0.6958
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.033 0.1191
Loa Loa (eye worm) hypothetical protein 0.0067 0.028 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0076 0.0268
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Brugia malayi PHD-finger family protein 0.0027 0.0042 0.0056
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0596 0.1909
Brugia malayi PXA domain containing protein 0.0021 0.0004 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0037 0.013
Leishmania major heat shock protein 83-1 0.0086 0.0395 0.048
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0071 0.025
Loa Loa (eye worm) hypothetical protein 0.0485 0.2804 0.3792
Onchocerca volvulus 0.0196 0.1063 0.375
Brugia malayi nuclear receptor RXR 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0134 0.0687 0.0929
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0096 0.0458 0.0619
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0052 0.0193 0.1
Echinococcus multilocularis zinc finger protein 0.0021 0.0007 0.0007
Echinococcus granulosus lamin dm0 0.003 0.0055 0.0177
Brugia malayi Cation transporter family protein 0.0196 0.1063 0.1437
Treponema pallidum hypothetical protein 0.012 0.0603 0.3213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0113 0.0399
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0016 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0071 0.025
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0026 0.0026
Brugia malayi bZIP transcription factor family protein 0.0181 0.097 0.1312
Entamoeba histolytica hypothetical protein 0.0113 0.0557 0.3077
Schistosoma mansoni acetylcholine receptor subunit beta 0.0095 0.0451 0.1447
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0157 0.0822 0.0822
Leishmania major protein kinase, putative 0.0056 0.0218 0.0265
Trypanosoma brucei heat shock protein, putative 0.0086 0.0395 0.0479
Schistosoma mansoni steroid hormone receptor ad4bp 0.0096 0.0458 0.1468
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0044 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.007 0.0246
Loa Loa (eye worm) hypothetical protein 0.0086 0.0399 0.0539
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0007 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0012
Schistosoma mansoni endoplasmin 0.0086 0.0395 0.1265
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0095 0.0451 0.061
Loa Loa (eye worm) ACC-1 protein 0.0196 0.1063 0.1437
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Onchocerca volvulus 0.0045 0.0151 0.0533
Toxoplasma gondii heat shock protein 75, putative 0.0048 0.0166 0.0863
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0151 0.0204
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0007 0.0024
Onchocerca volvulus 0.0196 0.1063 0.375
Brugia malayi jmjC domain containing protein 0.0066 0.0278 0.0377
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Loa Loa (eye worm) hypothetical protein 0.0045 0.0151 0.0204
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0451 0.061
Plasmodium falciparum heat shock protein 90, putative 0.0044 0.0141 0.0733
Trypanosoma cruzi heat shock protein, putative 0.0048 0.0166 0.0202
Loa Loa (eye worm) hypothetical protein 0.0264 0.147 0.1988
Loa Loa (eye worm) hypothetical protein 0.0075 0.033 0.0446
Plasmodium falciparum heat shock protein 90, putative 0.0205 0.1113 0.5774
Schistosoma mansoni thyroid hormone receptor 0.0234 0.129 0.4134
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.1809 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0153 0.0803 0.0803
Schistosoma mansoni hypothetical protein 0.01 0.0479 0.1536
Brugia malayi hypothetical protein 0.004 0.0119 0.0161
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0095 0.0451 0.061
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0016 0.0021
Loa Loa (eye worm) chitinase I 0.0073 0.0319 0.0432
Schistosoma mansoni ap endonuclease 0.0037 0.01 0.032
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Chlamydia trachomatis zinc metalloprotease 0.012 0.0603 0.3127
Loa Loa (eye worm) hypothetical protein 0.0311 0.1756 0.2374
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0096 0.0458 0.0619
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0068 0.0286 0.0347
Loa Loa (eye worm) hypothetical protein 0.0055 0.0207 0.0279
Onchocerca volvulus Putative endochitinase 0.0073 0.0319 0.1127
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0255 0.0818
Brugia malayi Bromodomain containing protein 0.0082 0.0373 0.0504
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0196 0.1063 0.3407
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0004 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0207 0.0279
Schistosoma mansoni thyroid hormone receptor 0.0234 0.129 0.4134
Brugia malayi cytosol aminopeptidase 0.0068 0.0286 0.0386
Brugia malayi hypothetical protein 0.0021 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Onchocerca volvulus 0.0091 0.0427 0.1505
Loa Loa (eye worm) hypothetical protein 0.067 0.3925 0.5306
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.061
Echinococcus granulosus expressed protein 0.0408 0.2344 0.7512
Entamoeba histolytica hypothetical protein 0.0113 0.0557 0.3077
Onchocerca volvulus 0.003 0.0055 0.0195
Schistosoma mansoni hypothetical protein 0.0147 0.0766 0.2453
Echinococcus multilocularis thyroid hormone receptor alpha 0.0234 0.129 0.129
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0004 0.0005
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0339 0.1927 0.6313
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Echinococcus multilocularis nAChR subunit 0.0196 0.1063 0.1063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0196 0.1063 0.1437
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0196 0.1063 0.1437
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0151 0.0151
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.01 0.0121
Brugia malayi hypothetical protein 0.0142 0.0736 0.0995
Loa Loa (eye worm) hypothetical protein 0.0042 0.0131 0.0177
Giardia lamblia NADPH oxidoreductase, putative 0.0082 0.037 0.172
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1809 0.6382
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0032 0.0164
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0557 0.1785
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0196 0.1063 0.1437
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0363 0.1162
Brugia malayi beta-lactamase family protein 0.0075 0.033 0.0446
Giardia lamblia Fructose-bisphosphate aldolase 0.032 0.1809 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0596 0.309
Trichomonas vaginalis set domain proteins, putative 0.049 0.2834 1
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.037 0.1305
Plasmodium vivax falcilysin, putative 0.012 0.0603 0.1974
Onchocerca volvulus 0.0196 0.1063 0.375
Trichomonas vaginalis heat shock protein, putative 0.0071 0.0307 0.1083
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0004 0.0012
Onchocerca volvulus 0.0075 0.033 0.1164
Loa Loa (eye worm) hypothetical protein 0.003 0.0055 0.0075
Echinococcus granulosus expressed protein 0.0052 0.0193 0.0618
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0071 0.037
Mycobacterium leprae conserved hypothetical protein 0.0075 0.033 0.1712
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.033 0.1057
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0096 0.0458 0.1468
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.01 0.032
Echinococcus multilocularis dual specificity 0.0088 0.041 0.041
Entamoeba histolytica hypothetical protein 0.0088 0.041 0.2268
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0016 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0037 0.013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0196 0.1063 0.1437
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0044 0.0053
Onchocerca volvulus Matrix metalloproteinase homolog 0.0148 0.0772 0.2722
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0138
Brugia malayi hypothetical protein 0.0179 0.0956 0.1292
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0095 0.0451 0.0451
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0068 0.0286 0.0386
Loa Loa (eye worm) hypothetical protein 0.0101 0.0489 0.0661
Brugia malayi beta-lactamase 0.0075 0.033 0.0446
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0068 0.0286 0.0386
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0196 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0059
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0243 0.1343 0.1343
Loa Loa (eye worm) hypothetical protein 0.0051 0.0184 0.0249

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 70 % Antiviral activity against acyclovir-resistant HSV1 AR29 replication in Vero cells at 50 uM after 72 hrs ChEMBL. 17937990

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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