Detailed information for compound 573681

Basic information

Technical information
  • TDR Targets ID: 573681
  • Name: ammonium 4-[(2-bromoacetyl)amino]benzenesulfo nate
  • MW: 311.153 | Formula: C8H11BrN2O4S
  • H donors: 2 H acceptors: 4 LogP: -2.45 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: BrCC(=O)Nc1ccc(cc1)S(=O)(=O)[O-].[NH4+]
  • InChi: 1S/C8H8BrNO4S.H3N/c9-5-8(11)10-6-1-3-7(4-2-6)15(12,13)14;/h1-4H,5H2,(H,10,11)(H,12,13,14);1H3
  • InChiKey: MAPKPCWBYRIZKV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ammonium 4-[(2-bromo-1-oxoethyl)amino]benzenesulfonate
  • azanium 4-(2-bromoethanoylamino)benzenesulfonate
  • ammonium 4-[(2-bromoacetyl)amino]besylate
  • azanium 4-[(2-bromoacetyl)amino]benzenesulfonate
  • bromoacetylsulfanilic acid
  • 61389-09-1
  • Benzenesulfonic acid, 4-((bromoacetyl)amino)-, monoammonium salt
  • Bromoacetylsulfanilic acid ammonium salt
  • Ammonium bromoacetylsulfanilate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0016 0.0045 0.0058
Schistosoma mansoni hypothetical protein 0.0017 0.0058 0.0075
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.1498 0.4007
Schistosoma mansoni DNA polymerase eta 0.0166 0.1654 0.2198
Trypanosoma cruzi DNA polymerase eta, putative 0.0088 0.0825 0.0824
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0292 0.0386
Mycobacterium tuberculosis Conserved protein 0.0039 0.0292 0.056
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0045 0.0058
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0477 0.0537
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0283 0.0755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Schistosoma mansoni hypothetical protein 0.0034 0.0242 0.0319
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0009 0.0008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0112 0.1077 0.1431
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0248 0.0247
Leishmania major pantothenate kinase subunit, putative 0.0015 0.0034 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0295 0.0792
Brugia malayi mbt repeat family protein 0.0049 0.0404 0.1079
Echinococcus multilocularis voltage dependent calcium channel 0.0097 0.0921 0.1038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.055 0.073
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0292 0.0779
Brugia malayi Flap endonuclease-1 0.0055 0.0465 0.1243
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0132 0.129 0.1289
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.1385 0.3712
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0009 0.0008
Onchocerca volvulus 0.0029 0.0188 0.0786
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0133 0.1299 0.1298
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0055 0.0465 0.0463
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0404 0.0454
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0012 0.0009 0.0019
Mycobacterium ulcerans lipase LipD 0.0039 0.0292 0.056
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0158 0.042
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0411 0.1099
Schistosoma mansoni glutaminase 0.0274 0.2814 0.3741
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0109 0.0287
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0012 0.0002 0.0004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0158 0.0208
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0039 0.0299 0.0396
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0045 0.0058
Echinococcus granulosus cpg binding protein 0.0031 0.0206 0.0271
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0041 0.0319 0.0422
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.1498 0.2875
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0019 0.0051
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0051 0.0423 0.0476
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0002 0.0004
Entamoeba histolytica Flap nuclease, putative 0.0055 0.0465 0.1243
Leishmania major phosphoglycerate kinase C, glycosomal 0.0359 0.3729 0.3728
Trichomonas vaginalis DNA helicase recq, putative 0.0096 0.0902 0.2419
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.067 0.0669
Echinococcus multilocularis dna polymerase eta 0.0166 0.1654 0.1866
Plasmodium vivax 6-phosphofructokinase, putative 0.0061 0.0528 0.1417
Brugia malayi beta-lactamase family protein 0.0039 0.0292 0.0779
Mycobacterium ulcerans 6-phosphofructokinase 0.0225 0.2293 0.4402
Echinococcus granulosus neuropeptide s receptor 0.0457 0.4783 0.636
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Plasmodium falciparum DNase I-like protein, putative 0.0012 0.0002 0.0004
Onchocerca volvulus 0.0016 0.0045 0.0185
Brugia malayi nuclear receptor NHR-88 0.0026 0.0158 0.042
Leishmania major phosphoglycerate kinase B, cytosolic 0.0359 0.3729 0.3728
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.0055 0.0469 0.1254
Leishmania major hypothetical protein, conserved 0.0039 0.0292 0.029
Brugia malayi orphan nuclear receptor NR2E1 0.0012 0.0009 0.0019
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0013 0.0019 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.1385 0.1841
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0109 0.0209
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0158 0.0208
Schistosoma mansoni nuclear receptor 0.0012 0.0009 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0437 0.0839
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0034 0.0236 0.0311
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0158 0.0177
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0051 0.0424 0.0422
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0295 0.0332
Echinococcus granulosus GPCR family 2 0.0016 0.0045 0.0058
Brugia malayi hypothetical protein 0.0017 0.0058 0.0152
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0248 0.0662
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0246 0.0655
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0158 0.0208
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0359 0.3729 0.3728
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0295 0.0332
Schistosoma mansoni SET domain protein 0.0013 0.002 0.0024
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0109 0.0209
Echinococcus granulosus voltage dependent calcium channel 0.0097 0.0921 0.1223
Schistosoma mansoni hypothetical protein 0.0013 0.0017 0.0021
Loa Loa (eye worm) oxidoreductase 0.0022 0.0109 0.0287
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0016 0.0046 0.012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0295 0.0788
Loa Loa (eye worm) hypothetical protein 0.0074 0.067 0.1793
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0404 0.0454
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0039 0.0299 0.0336
Loa Loa (eye worm) X11 protein 0.007 0.0623 0.1666
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0062
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0109 0.0107
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0477 0.0632
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0062 0.0544 0.1454
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0027 0.0026
Echinococcus granulosus geminin 0.0352 0.3657 0.4863
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0061 0.0528 0.1413
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0292 0.029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0501 0.0961
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.067 0.1287
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0283 0.0282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0009 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Toxoplasma gondii hypothetical protein 0.0018 0.0068 0.0178
Echinococcus granulosus thyroid hormone receptor alpha 0.0012 0.0009 0.001
Echinococcus multilocularis dna polymerase kappa 0.0168 0.1679 0.1894
Echinococcus granulosus Helicase RNase D C terminal HRDC domain 0.0012 0.0006 0.0005
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0019 0.0023
Echinococcus multilocularis GPCR, family 2 0.0016 0.0045 0.0049
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0292 0.056
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0501 0.1343
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.0248 0.0666
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0027 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0283 0.0759
Toxoplasma gondii 3'-5' exonuclease domain-containing protein 0.0012 0.0006 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0292 0.0782
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0051 0.0423 0.0561
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0299 0.0798
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0109 0.0107
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0027 0.0108
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0225 0.2293 0.6143
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0404 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0158 0.042
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.067 0.1287
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0069
Plasmodium vivax flap endonuclease 1, putative 0.0055 0.0465 0.1247
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0158 0.0208
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0295 0.0391
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0158 0.042
Toxoplasma gondii hypothetical protein 0.0051 0.0423 0.1131
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0158 0.0208
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0061 0.0528 0.1413
Onchocerca volvulus 0.0049 0.0404 0.1697
Schistosoma mansoni coup transcription factor 0.0026 0.0158 0.0208
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0477 0.1275
Brugia malayi steroid hormone receptor 0.0026 0.0158 0.042
Brugia malayi nuclear hormone receptor family member nhr-6 0.0012 0.0009 0.0019
Entamoeba histolytica recQ family DNA helicase 0.002 0.0091 0.0241
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0246 0.0244
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0283 0.0759
Onchocerca volvulus 0.0016 0.0045 0.0185
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0076 0.0146
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0249
Giardia lamblia DINP protein human, muc B family 0.0126 0.1226 0.3286
Mycobacterium ulcerans hypothetical protein 0.0074 0.067 0.1287
Brugia malayi ThiF family protein 0.0051 0.0423 0.1131
Schistosoma mansoni nuclear receptor 0.0012 0.0009 0.001
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0109 0.0291
Onchocerca volvulus 0.0017 0.0058 0.0239
Onchocerca volvulus 0.0026 0.0158 0.0661
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0067 0.0593 0.1587
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0158 0.0208
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0027 0.0073
Plasmodium falciparum flap endonuclease 1 0.0055 0.0465 0.1247
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0283 0.0759
Schistosoma mansoni cpg binding protein 0.0031 0.0206 0.0271
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0133 0.1299 0.1298
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0158 0.0177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Schistosoma mansoni hypothetical protein 0.0111 0.107 0.1422
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0158 0.0208
Onchocerca volvulus 0.0099 0.0938 0.3954
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0019 0.0051
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0109 0.0287
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0158 0.0177
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0109 0.0107
Echinococcus granulosus dnaJ subfamily B 0.0415 0.4325 0.5751
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Loa Loa (eye worm) hypothetical protein 0.0056 0.0477 0.1275
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0501 0.1339
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0158 0.042
Leishmania major ATP-dependent phosphofructokinase 0.0225 0.2293 0.2292
Echinococcus multilocularis phosphoglycerate kinase 1 0.0359 0.3729 0.4209
Chlamydia trachomatis phosphoglycerate kinase 0.0359 0.3729 1
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0002 0.0004
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0109 0.0209
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0012 0.0002 0.0004
Mycobacterium ulcerans beta-lactamase 0.0039 0.0292 0.056
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Leishmania major exosome subunit rrp6p homologue, putative 0.0012 0.0006 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0943 1 1
Plasmodium vivax exodeoxyribonuclease III, putative 0.0012 0.0002 0.0004
Onchocerca volvulus 0.0039 0.0292 0.1225
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0013 0.0019 0.0046
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0073
Loa Loa (eye worm) DOMON domain-containing protein 0.0016 0.0045 0.0117
Mycobacterium ulcerans hypothetical protein 0.0039 0.0292 0.056
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0009 0.003
Echinococcus multilocularis Eukaryotic translation initiation factor 4H 0.0143 0.1407 0.1587
Entamoeba histolytica hypothetical protein 0.0111 0.107 0.2867
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0528 0.1417
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0084 0.0777 0.2085
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0109 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0158 0.042
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Schistosoma mansoni polymyositis/scleroderma autoantigen-related 0.0012 0.0006 0.0005
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0109 0.0107
Plasmodium vivax ubiquitin activating enzyme, putative 0.0051 0.0423 0.1134
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0299 0.0798
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0109 0.0121
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0027 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0158 0.0208
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0045 0.0116
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0158 0.042
Trypanosoma brucei phosphoglycerate kinase 0.0132 0.129 0.1289
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0062
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0051 0.0424 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0109 0.0291
Schistosoma mansoni SET domain protein 0.0035 0.0252 0.0333
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0178
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0248 0.0247
Toxoplasma gondii ABC1 family protein 0.0039 0.0292 0.0779
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0009 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0501 0.1343
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.1385 0.1841
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0109 0.0287
Mycobacterium ulcerans DNA polymerase IV 0.0168 0.1679 0.3224
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0248 0.0247
Echinococcus multilocularis cpg binding protein 0.0031 0.0206 0.023
Leishmania major DNA polymerase kappa, putative 0.0035 0.0248 0.0247
Schistosoma mansoni hypothetical protein 0.0352 0.3657 0.4863
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0528 0.1417
Trichomonas vaginalis phosphofructokinase, putative 0.0225 0.2293 0.6148
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0469 0.1258
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0283 0.0759
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0027 0.0026
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0027 0.0073
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.107 0.1422
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0528 0.1417
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0002 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Mycobacterium leprae Probable lipase LipE 0.0039 0.0292 0.0769
Trichomonas vaginalis DNA helicase recq1, putative 0.0096 0.0902 0.2419
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.0248 0.0247
Schistosoma mansoni ap endonuclease 0.0058 0.0501 0.0664
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0404 0.0535
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0126 0.1226 0.1225
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0404 0.1697
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Brugia malayi conserved hypotetical protein 0.0012 0.0009 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.067 0.1287
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Trypanosoma brucei phosphoglycerate kinase, putative 0.0132 0.129 0.1289
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0002 0.0004
Onchocerca volvulus 0.0039 0.0292 0.1225
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0061 0.0528 0.1417
Loa Loa (eye worm) hypothetical protein 0.0359 0.3729 1
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0158 0.042
Echinococcus granulosus amyloid beta A4 protein 0.007 0.0623 0.0826
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0126 0.1226 0.2355
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0027 0.0069
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.067 0.1287
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0437 0.0839
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0025 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0015
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0283 0.0375
Schistosoma mansoni nuclear receptor nhr-48 0.0012 0.0009 0.001
Brugia malayi Phosphoglycerate kinase 0.0359 0.3729 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.0117
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0061 0.0528 0.1417
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0034 0.0236 0.0311
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0158 0.0661
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.1385 0.1841
Giardia lamblia DNA damage repair protein 0.0035 0.0248 0.0662
Trypanosoma cruzi DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0109 0.0142
Echinococcus granulosus MAM 0.0017 0.0058 0.0075
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0283 0.0318
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.067 0.0669
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0501 0.1343
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.067 0.1785
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0437 0.0839
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Echinococcus granulosus flap endonuclease 1 0.0055 0.0465 0.0616
Brugia malayi hypothetical protein 0.0111 0.107 0.2867
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0132 0.129 0.1289
Brugia malayi ImpB/MucB/SamB family protein 0.0112 0.1077 0.2885
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.0116
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0088 0.0825 0.2209
Mycobacterium tuberculosis Conserved hypothetical protein 0.0497 0.5208 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0292 0.0782
Brugia malayi hypothetical protein 0.0014 0.0025 0.0062
Schistosoma mansoni cpg binding protein 0.0031 0.0206 0.0271
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.0117
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0158 0.0208
Loa Loa (eye worm) flap endonuclease-1 0.0055 0.0465 0.1243
Toxoplasma gondii exonuclease III APE 0.0058 0.0501 0.1339
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0158 0.0177
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0133 0.1299 0.1298
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.0166 0.1654 0.4433
Trypanosoma brucei unspecified product 0.0077 0.0704 0.0703
Echinococcus multilocularis microtubule associated protein 2 0.0712 0.7519 0.8489
Onchocerca volvulus 0.0012 0.0009 0.003
Trichomonas vaginalis DNA polymerase eta, putative 0.0168 0.1679 0.4503
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0501 0.1339
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0109 0.0291
Loa Loa (eye worm) hypothetical protein 0.0055 0.0469 0.1254
Brugia malayi tailless protein 0.0012 0.0009 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0158 0.042
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0012 0.0009 0.0008
Schistosoma mansoni alpha-glucosidase 0.0147 0.1457 0.1937
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0292 0.056
Loa Loa (eye worm) hypothetical protein 0.0291 0.2997 0.8036
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0158 0.0208
Entamoeba histolytica phosphofructokinase, putative 0.0225 0.2293 0.6147
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0292 0.029
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0055 0.0465 0.0463
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0158 0.0177
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0411 0.1099
Echinococcus granulosus microtubule associated protein 2 0.0712 0.7519 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0501 0.1339
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative 0.0016 0.0046 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0158 0.042
Giardia lamblia Sgs1 DNA helicase, putative 0.0039 0.0299 0.0798
Echinococcus granulosus Eukaryotic translation initiation factor 4H 0.0143 0.1407 0.187
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0109 0.0209
Schistosoma mansoni phosphoglycerate kinase 0.0359 0.3729 0.4958
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0158 0.042
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0055 0.0465 0.0463
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0292 0.056
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0109 0.0209
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.067 0.1287
Echinococcus multilocularis MAM 0.0017 0.0058 0.0064
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0039 0.0299 0.0336
Loa Loa (eye worm) hypothetical protein 0.0017 0.0058 0.0152
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0295 0.0391
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0404 0.0535
Schistosoma mansoni hypothetical protein 0.0311 0.3214 0.4273
Entamoeba histolytica exosome component 10, putative 0.0012 0.0006 0.0011
Toxoplasma gondii transporter, cation channel family protein 0.002 0.0094 0.0249
Brugia malayi glutaminase DH11.1 0.0274 0.2814 0.7546
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.067 0.1793
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0404 0.0535
Brugia malayi AMP-binding enzyme family protein 0.0074 0.067 0.1793
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0246 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0158 0.042
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0013 0.0019 0.0023
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0359 0.3729 1
Entamoeba histolytica hypothetical protein 0.0111 0.107 0.2867
Brugia malayi hypothetical protein 0.0067 0.0593 0.1587
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0058 0.0152
Leishmania major hypothetical protein, conserved 0.0013 0.0019 0.0017
Echinococcus granulosus lysosomal alpha glucosidase 0.0171 0.1713 0.2277
Trichomonas vaginalis glutaminase, putative 0.0274 0.2814 0.7547
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0109 0.0107
Onchocerca volvulus 0.0233 0.2371 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0109 0.0287
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0359 0.3729 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.2084 0.2351
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0045 0.0049
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0283 0.0759
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0002 0.0004
Mycobacterium ulcerans DNA polymerase IV 0.0168 0.1679 0.3224
Trichomonas vaginalis dullard protein, putative 0.0013 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.0039 0.0295 0.0788
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0061 0.0528 0.1417
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0158 0.0208
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0073
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0061 0.0528 0.0182
Trichomonas vaginalis DNA helicase recq, putative 0.0051 0.0424 0.1137
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0158 0.0208
Loa Loa (eye worm) RecQ helicase 0.0096 0.0902 0.2416
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0501 0.0664
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0248 0.0247
Loa Loa (eye worm) glutaminase 0.0274 0.2814 0.7546
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0051 0.0423 0.0561
Loa Loa (eye worm) hypothetical protein 0.0049 0.0404 0.1079
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0019 0.0083 0.0223
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0064 0.0561 0.1502
Trypanosoma brucei DNA polymerase IV, putative 0.0168 0.1679 0.1678
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0091 0.0241
Trypanosoma brucei DNA polymerase eta, putative 0.0166 0.1654 0.1653
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0109 0.0287
Brugia malayi polk-prov protein 0.0091 0.085 0.2277
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0295 0.0788
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0446 0.4667 0.4666
Plasmodium falciparum phosphoglycerate kinase 0.0359 0.3729 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0283 0.0755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0158 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0295 0.0332
Schistosoma mansoni rotamase 0.0035 0.0255 0.0337
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0133 0.1299 0.1298
Trichomonas vaginalis phosphofructokinase, putative 0.0225 0.2293 0.6148
Trypanosoma brucei DNA polymerase kappa, putative 0.0091 0.085 0.0849
Trypanosoma brucei DNA polymerase kappa, putative 0.0091 0.0853 0.0852
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0109 0.0287
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0061 0.0528 0.0182
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0158 0.0208
Loa Loa (eye worm) hypothetical protein 0.0039 0.0299 0.0798
Trichomonas vaginalis rotamase, putative 0.0035 0.0255 0.0683
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0109 0.0291
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0143 0.1407 0.187
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.067 0.1785
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0012 0.0002 0.0004
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0055 0.0469 0.1254
Schistosoma mansoni amyloid beta A4 protein related 0.007 0.0623 0.0826
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0045 0.0049
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.1498 0.2875
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0943 1 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.085 0.2277
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0158 0.0208
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0943 1 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0055 0.0465 0.1243
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0158 0.0177
Schistosoma mansoni ap endonuclease 0.0058 0.0501 0.0664
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0248 0.0247
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.067 0.1287
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0109 0.0209
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0158 0.042
Loa Loa (eye worm) hypothetical protein 0.002 0.0091 0.0241
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0012 0.0009 0.001
Leishmania major DNA polymerase kappa, putative 0.0126 0.1226 0.1225
Brugia malayi nuclear hormone receptor family member odr-7 0.0012 0.0009 0.0019
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0109 0.0277
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0039 0.0299 0.0798
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Trypanosoma brucei phosphoglycerate kinase 0.0359 0.3729 0.3728
Loa Loa (eye worm) hypothetical protein 0.0055 0.0469 0.1254
Trichomonas vaginalis rotamase, putative 0.0035 0.0246 0.0659
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0091 0.085 0.0849
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0158 0.042
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0143 0.1407 0.187
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0109 0.0209
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0109 0.0277
Schistosoma mansoni hypothetical protein 0.0415 0.4325 0.5751
Echinococcus granulosus voltage dependent calcium channel 0.002 0.0094 0.0123
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0158 0.042
Brugia malayi ImpB/MucB/SamB family protein 0.0166 0.1654 0.4433
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0035 0.0252 0.0283
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0287
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0051 0.0423 0.1134
Echinococcus granulosus neuropeptide receptor A26 0.0457 0.4783 0.636
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0025 0.0062
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0012 0.0009 0.0019
Schistosoma mansoni 6-phosphofructokinase 0.0225 0.2293 0.3048
Trypanosoma cruzi DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Loa Loa (eye worm) hypothetical protein 0.0039 0.0292 0.0779
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0292 0.029
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0292 0.056
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0248 0.0247
Entamoeba histolytica deoxycytidyl transferase, putative 0.0112 0.1077 0.2885
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0015 0.0034 0.0032
Onchocerca volvulus 0.0022 0.0109 0.0452
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0073
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.107 0.1422
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0283 0.0759
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0025 0.0062
Toxoplasma gondii phosphofructokinase PFKII 0.0061 0.0528 0.1413
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0013 0.0019 0.0019
Echinococcus granulosus dna polymerase kappa 0.0168 0.1679 0.2232
Brugia malayi ecdysone receptor 0.0012 0.0009 0.0019
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0225 0.2293 0.2292
Brugia malayi beta-lactamase family protein 0.0039 0.0292 0.0779
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0097 0.0921 0.1223
Onchocerca volvulus 0.0016 0.0045 0.0185
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0158 0.042
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.0019 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.1385 0.1841
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0158 0.0208
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0295 0.0294
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0109 0.0287
Schistosoma mansoni hypothetical protein 0.0016 0.0045 0.0058
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0292 0.056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0501 0.0499
Loa Loa (eye worm) hypothetical protein 0.0039 0.0292 0.0779
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0404 0.0535
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0012 0.0002 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0292 0.0386
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.1385 0.1563
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0109 0.0209
Echinococcus multilocularis amyloid beta A4 protein 0.007 0.0623 0.0701
Loa Loa (eye worm) hypothetical protein 0.0051 0.0423 0.1131
Mycobacterium ulcerans phosphoglycerate kinase 0.0359 0.3729 0.716
Loa Loa (eye worm) hypothetical protein 0.0017 0.0058 0.0152
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0295 0.0294
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0404 0.1079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0158 0.042
Loa Loa (eye worm) hypothetical protein 0.0039 0.0292 0.0779
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.1713 0.1933
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0062
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.1099
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0109 0.0209
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0837 0.8858 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0469 0.1258
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0109 0.0107
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0025 0.0031
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0242 0.0644
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0009 0.0019
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0295 0.0294
Echinococcus multilocularis flap endonuclease 1 0.0055 0.0465 0.0523
Loa Loa (eye worm) ThiF family protein 0.0034 0.0236 0.0628
Loa Loa (eye worm) hypothetical protein 0.0034 0.0242 0.0644
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0027 0.0069
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.067 0.1793
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.0248 0.0328
Loa Loa (eye worm) nuclear receptor NHR-67 0.0012 0.0009 0.0019
Echinococcus multilocularis voltage dependent calcium channel 0.0097 0.0921 0.1038
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0034 0.0236 0.0234
Trypanosoma brucei ribosomal RNA processing protein 6 0.0012 0.0006 0.0004
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0109 0.0209
Loa Loa (eye worm) nuclear hormone receptor 0.0012 0.0009 0.0019
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0501 0.1339
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0158 0.0208
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0097 0.0921 0.1223
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0061 0.0528 0.1413
Schistosoma mansoni alpha glucosidase 0.0038 0.0283 0.0375
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0039 0.0299 0.0396
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0501 0.1339
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0013 0.0019 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0109 0.0287
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0292 0.0782
Brugia malayi Pax transcription factor protein 2 0.0233 0.2371 0.6357
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0295 0.0294
Loa Loa (eye worm) hypothetical protein 0.0097 0.0921 0.2466
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0109 0.0209
Toxoplasma gondii hypothetical protein 0.0152 0.1508 0.4042
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0359 0.3729 0.3728
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0469 0.0901
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0012 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0178
Loa Loa (eye worm) hypothetical protein 0.0039 0.0292 0.0779
Plasmodium vivax exosome complex exonuclease RRP6, putative 0.0012 0.0006 0.0015
Echinococcus multilocularis 0.0013 0.0019 0.0019
Leishmania major DNA polymerase eta, putative 0.0166 0.1654 0.1653
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0097 0.0921 0.1223
Echinococcus granulosus nuclear receptor nhr 48 0.0012 0.0009 0.001
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0012 0.0002 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.1385 0.1563
Loa Loa (eye worm) 3'-5' exonuclease 0.0012 0.0006 0.0011
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0292 0.056
Entamoeba histolytica phosphoglycerate kinase, putative 0.0359 0.3729 1
Loa Loa (eye worm) DR-78 0.0012 0.0009 0.0019
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.067 0.1793
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0109 0.0209
Brugia malayi hypothetical protein 0.0012 0.0009 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0295 0.0792
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0283 0.0759
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0097 0.0921 0.1038
Echinococcus granulosus phosphoglycerate kinase 1 0.0359 0.3729 0.4958
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Loa Loa (eye worm) TK/ALK protein kinase 0.0017 0.0058 0.0152
Echinococcus multilocularis nuclear receptor nhr 48 0.0012 0.0009 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.3196 0.857
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0019 0.0051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0501 0.0499
Schistosoma mansoni DNA helicase recq5 0.0039 0.0299 0.0396
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0109 0.0287
Trichomonas vaginalis esterase, putative 0.0039 0.0292 0.0782
Schistosoma mansoni 6-phosphofructokinase 0.0225 0.2293 0.3048
Brugia malayi beta-lactamase 0.0039 0.0292 0.0779
Mycobacterium tuberculosis Probable exported protein 0.0012 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0016 0.0045 0.0058
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0248 0.2536 0.487
Treponema pallidum ATP-dependent DNA helicase 0.002 0.0091 0.0241
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0359 0.3729 1
Trichomonas vaginalis dullard protein, putative 0.0013 0.0019 0.0051
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0246 0.0244
Loa Loa (eye worm) hypothetical protein 0.0074 0.067 0.1793
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0051 0.0424 0.0422
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0046 0.0373 0.0494
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0109 0.0209
Trypanosoma brucei glucosidase, putative 0.0038 0.0283 0.0282
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0283 0.0755
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0049 0.0398 0.1063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0158 0.042
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0091 0.009
Schistosoma mansoni hypothetical protein 0.0016 0.0045 0.0058
Entamoeba histolytica hypothetical protein 0.0111 0.107 0.2867
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.3196 0.857
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0287
Trypanosoma brucei DNA polymerase kappa, putative 0.0091 0.0853 0.0852
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Trypanosoma brucei DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Mycobacterium tuberculosis Conserved hypothetical protein 0.0112 0.1077 0.2068
Plasmodium vivax phosphoglycerate kinase, putative 0.0359 0.3729 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0109 0.0209
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0528 0.1417
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0477 0.0632
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0295 0.0391
Trypanosoma brucei phosphoglycerate kinase 0.0359 0.3729 0.3728
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0292 0.0782
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.067 0.1287
Trypanosoma brucei DNA polymerase IV, putative 0.0154 0.153 0.1528
Schistosoma mansoni microtubule-associated protein tau 0.0712 0.7519 1
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0029 0.0185 0.0184
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0158 0.0208
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0012 0.0002 0.0004
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0477 0.0632
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0091 0.0119
Schistosoma mansoni hypothetical protein 0.0017 0.0058 0.0075
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0009 0.003
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0097 0.0921 0.1223
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0109 0.0287
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0292 0.0386
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0359 0.3729 0.716
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0446 0.4667 0.4666
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0014 0.0025 0.0047
Brugia malayi nuclear hormone receptor 0.0012 0.0009 0.0019
Brugia malayi Bloom's syndrome protein homolog 0.0096 0.0902 0.2416
Trypanosoma cruzi DNA polymerase kappa, putative 0.0168 0.1679 0.1678
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0034 0.0236 0.0234
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0132 0.129 0.1289
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0295 0.0391
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.1385 0.3712
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0013 0.0019 0.0051
Loa Loa (eye worm) MBCTL1 0.0056 0.0477 0.1275
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0025 0.0031
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0283 0.0755
Plasmodium vivax 6-phosphofructokinase, putative 0.0061 0.0528 0.1417
Giardia lamblia Phosphoglycerate kinase 0.0359 0.3729 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0158 0.042
Onchocerca volvulus 0.0022 0.0109 0.0452
Trichomonas vaginalis phosphofructokinase, putative 0.0225 0.2293 0.6148
Loa Loa (eye worm) hypothetical protein 0.0074 0.067 0.1793
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0019 0.0023
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0013 0.0019 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0292 0.0782
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0109 0.0287
Entamoeba histolytica phosphofructokinase, putative 0.0225 0.2293 0.6147
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0477 0.0537
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0248 0.0247
Onchocerca volvulus 0.0022 0.0109 0.0452
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0055 0.0469 0.1254
Schistosoma mansoni terminal deoxycytidyl transferase 0.0112 0.1077 0.1431
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0292 0.0769
Treponema pallidum fructose-bisphosphate aldolase 0.0309 0.3196 0.857
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0162 0.161 0.1609
Trypanosoma cruzi ubiquitin-activating enzyme-like protein 0.0016 0.0046 0.0045
Brugia malayi nuclear receptor NHR-67 0.0012 0.0009 0.0019
Leishmania major DNA damage repair protein, putative 0.0035 0.0248 0.0247
Brugia malayi Protein kinase domain containing protein 0.0017 0.0058 0.0152
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0299 0.0798
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0109 0.0287
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0292 0.056
Loa Loa (eye worm) phosphofructokinase 0.0225 0.2293 0.6147
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0158 0.042
Brugia malayi nuclear receptor RXR 0.0014 0.0025 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Giardia lamblia Flap structure-specific endonuclease 0.0055 0.0465 0.1243
Loa Loa (eye worm) glutaminase 2 0.0274 0.2814 0.7546
Leishmania major DNA polymerase eta, putative 0.0088 0.0825 0.0824
Brugia malayi AMP-binding enzyme family protein 0.0074 0.067 0.1793
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0109 0.0142
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0073
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0501 0.1343
Loa Loa (eye worm) 6-phosphofructokinase 0.0225 0.2293 0.6147
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0109 0.0209
Echinococcus multilocularis neuropeptide s receptor 0.0457 0.4783 0.5399
Echinococcus granulosus bloom syndrome protein 0.0096 0.0902 0.1198
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0225 0.2293 0.6147
Brugia malayi hypothetical protein 0.0014 0.0025 0.0062
Schistosoma mansoni hypothetical protein 0.0352 0.3657 0.4863
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0034 0.0236 0.0632
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0042
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0065 0.057 0.1527
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Brugia malayi Phosphoglycerate kinase 0.0132 0.129 0.3456
Trichomonas vaginalis phosphofructokinase, putative 0.0225 0.2293 0.6148
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0292 0.0328
Echinococcus multilocularis geminin 0.0352 0.3657 0.4128
Echinococcus multilocularis 6 phosphofructokinase 0.0225 0.2293 0.2587
Brugia malayi Glycosyl hydrolases family 31 protein 0.0171 0.1713 0.4592
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0097 0.0921 0.1038
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0255 0.0683
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0059 0.0511 0.051
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0359 0.3729 1
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0292 0.056
Mycobacterium ulcerans hypothetical protein 0.0497 0.5208 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0299 0.0798
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0255 0.0679
Echinococcus multilocularis sodium channel protein 0.0041 0.0319 0.0358
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Echinococcus granulosus dna polymerase eta 0.0166 0.1654 0.2198
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0035 0.0252 0.0333
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0062
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0446 0.4667 0.4666
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0012 0.0009 0.001
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0097 0.0921 0.1223
Brugia malayi nuclear receptor RXR 0.0012 0.0009 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.1385 0.1841
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0046
Echinococcus granulosus expressed protein 0.0035 0.0255 0.0337
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 0.3196 0.857
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0009 0.001
Mycobacterium tuberculosis Conserved hypothetical alanine rich protein 0.0012 0.0006 0.0011
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0158 0.0661
Brugia malayi mbt repeat family protein 0.0049 0.0404 0.1079
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0034 0.0236 0.0264
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.067 0.1287
Echinococcus multilocularis neuropeptide receptor A26 0.0457 0.4783 0.5399
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0188 0.0499
Echinococcus multilocularis expressed protein 0.0035 0.0255 0.0286
Trypanosoma brucei unspecified product 0.0154 0.153 0.1528
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.2084 0.277
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0501 0.0961
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0012 0.0009 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0528 0.1417
Brugia malayi RNA binding protein 0.0143 0.1407 0.377
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0025 0.0062
Brugia malayi ecdysteroid receptor 0.0026 0.0158 0.042
Onchocerca volvulus 0.0016 0.0045 0.0185
Brugia malayi ThiF family protein 0.0034 0.0236 0.0628
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0246 0.0655
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0109 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.1226 0.1225
Onchocerca volvulus 0.0016 0.0045 0.0185
Schistosoma mansoni blooms syndrome DNA helicase 0.0076 0.0686 0.091
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0255 0.0679
Treponema pallidum phosphoglycerate kinase 0.0359 0.3729 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.067 0.0669
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0158 0.042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0158 0.042
Trichomonas vaginalis flap endonuclease-1, putative 0.0055 0.0465 0.1247
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0171 0.1713 0.4592
Schistosoma mansoni DNA helicase recq1 0.0039 0.0299 0.0396
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0295 0.0391
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0283 0.0759
Onchocerca volvulus 0.0022 0.0109 0.0452
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0225 0.2293 0.2292
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0437 0.0839
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0158 0.0177
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0158 0.0208
Echinococcus multilocularis bloom syndrome protein 0.0096 0.0902 0.1017
Loa Loa (eye worm) pax transcription factor protein 2 0.0233 0.2371 0.6357
Echinococcus granulosus CTD small phosphatase protein like 0.0013 0.0019 0.0023
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0225 0.2293 0.4402
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0132 0.129 0.1289
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0158 0.0661
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0109 0.0107
Brugia malayi CXXC zinc finger family protein 0.0029 0.0188 0.0499
Brugia malayi Muscle positioning protein 4 0.0016 0.0045 0.0117
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0109 0.0209
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0501 0.0499
Schistosoma mansoni alpha-glucosidase 0.0147 0.1457 0.1937
Schistosoma mansoni hypothetical protein 0.0016 0.0045 0.0058
Trypanosoma brucei unspecified product 0.0077 0.0704 0.0703
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0062
Loa Loa (eye worm) hypothetical protein 0.0039 0.0292 0.0779
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.107 0.1207
Echinococcus multilocularis dnaJ subfamily B 0.0415 0.4325 0.4882
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0097 0.0921 0.2466
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0158 0.0177
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0158 0.042
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0359 0.3729 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0097 0.0921 0.1038
Brugia malayi 6-phosphofructokinase 0.0225 0.2293 0.6147
Giardia lamblia Ubiquitin-activating enzyme E1 1 0.0016 0.0046 0.012
Entamoeba histolytica phosphofructokinase, putative 0.0225 0.2293 0.6147
Loa Loa (eye worm) voltage-dependent calcium channel 0.002 0.0094 0.0249
Loa Loa (eye worm) calcium channel 0.0097 0.0921 0.2466
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0061 0.0528 0.1413
Brugia malayi SEA domain containing protein 0.0016 0.0045 0.0117
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0083 0.0219
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.067 0.1287
Loa Loa (eye worm) 6-phosphofructokinase 0.0225 0.2293 0.6147
Brugia malayi AMP-binding enzyme family protein 0.0074 0.067 0.1793
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.1713 0.1933
Entamoeba histolytica recQ family helicase, putative 0.0051 0.0424 0.1133
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0411 0.1099
Trypanosoma brucei DNA polymerase kappa, putative 0.0091 0.0853 0.0852
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0073
Mycobacterium tuberculosis Conserved protein 0.0039 0.0292 0.056
Trypanosoma cruzi ribosomal RNA processing protein 6, putative 0.0012 0.0006 0.0004
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0501 0.0564
Trypanosoma brucei DNA polymerase IV, putative 0.0168 0.1679 0.1678
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0158 0.0208
Mycobacterium ulcerans hypothetical protein 0.0012 0.0006 0.0011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0112 0.1077 0.1431
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0359 0.3729 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0501 0.0499
Onchocerca volvulus 0.0039 0.0292 0.1225
Onchocerca volvulus 0.0074 0.067 0.2821
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0034 0.0236 0.0632
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0109 0.0107
Schistosoma mansoni phosphoglycerate kinase 0.0359 0.3729 0.4958
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0168 0.1679 0.4503
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0045 0.0116
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0097 0.0921 0.1038
Loa Loa (eye worm) beta-lactamase 0.0039 0.0292 0.0779
Leishmania major ubiquitin-activating enzyme-like protein 0.0034 0.0236 0.0234
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0059 0.0511 0.051
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0009 0.001
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0112 0.1077 0.2885
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0246 0.0244
Schistosoma mansoni zinc finger protein 0.0012 0.0009 0.001
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0002 0.0004
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.0248 0.0666
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0091 0.009
Brugia malayi nuclear hormone receptor 0.0026 0.0158 0.042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Mycobacterium ulcerans glutaminase 0.0274 0.2814 0.5403
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0283 0.0282
Schistosoma mansoni flap endonuclease-1 0.005 0.0408 0.0541
Trichomonas vaginalis Phospholipase C precursor, putative 0.0012 0.0002 0.0004
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0132 0.129 0.1289
Onchocerca volvulus 0.0017 0.0058 0.0239
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0469 0.0901
Mycobacterium ulcerans hypothetical protein 0.0035 0.0248 0.0477
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0158 0.0208
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0039 0.0299 0.0802
Toxoplasma gondii 6-phosphofructokinase 0.0061 0.0528 0.1413
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0158 0.042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0295 0.0788
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0045 0.0116
Trypanosoma cruzi DNA polymerase eta, putative 0.0166 0.1654 0.1653
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0143 0.1407 0.187
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0039 0.0292 0.0779
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0283 0.0759
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0132 0.129 0.1289
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0528 0.1417
Trichomonas vaginalis dullard protein, putative 0.0013 0.0019 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0248 0.0247
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0292 0.0779
Brugia malayi phosphofructokinase 0.0225 0.2293 0.6147
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0158 0.042
Echinococcus granulosus 6 phosphofructokinase 0.0225 0.2293 0.3048
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0158 0.0177
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0019 0.0051
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0012 0.0002 0.0004
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0109 0.0209
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0295 0.0792
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0109 0.0209
Brugia malayi 3'-5' exonuclease family protein 0.0012 0.0006 0.0011
Onchocerca volvulus 0.0012 0.0009 0.003
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0109 0.0277
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0112 0.1077 0.1214
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0283 0.0282
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0009 0.001
Brugia malayi nuclear receptor NHR-88 0.0012 0.0009 0.0019
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.048 0.1282
Schistosoma mansoni voltage-gated cation channel 0.0097 0.0921 0.1223
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3196 0.8571
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0292 0.0782
Toxoplasma gondii ThiF family protein 0.0034 0.0236 0.0628
Schistosoma mansoni cpg binding protein 0.0029 0.0188 0.0248
Brugia malayi 6-phosphofructokinase 0.0225 0.2293 0.6147
Echinococcus multilocularis Helicase RNase D C terminal, HRDC domain 0.0012 0.0006 0.0005
Mycobacterium tuberculosis Conserved protein 0.0039 0.0292 0.056
Entamoeba histolytica hypothetical protein 0.0111 0.107 0.2867
Loa Loa (eye worm) hypothetical protein 0.0143 0.1407 0.377
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0158 0.042
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0292 0.056
Brugia malayi hypothetical protein 0.0012 0.0009 0.0019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0283 0.0755

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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