Detailed information for compound 573754

Basic information

Technical information
  • TDR Targets ID: 573754
  • Name: N-[(10Z)-13-(2-amino-4-hydroxy-1,4,5,6-tetrah ydropyrimidin-6-yl)-4,7-bis(hydroxymethyl)-2, 5,8,11,14-pentaoxo-10-(ureidomethylene)-3,6,9 ,12,15-pentazacyclohexadec-1-yl]-5-guanidino- 3-(methylamino)pentanamide trihydrochloride
  • MW: 837.113 | Formula: C26H48Cl3N15O10
  • H donors: 16 H acceptors: 10 LogP: -5.02 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 3
  • SMILES: CNC(CC(=O)NC1CNC(=O)C(NC(=O)C(=CNC(=O)N)NC(=O)C(NC(=O)C(NC1=O)CO)CO)C1CC(O)N=C(N1)N)CCN=C(N)N.Cl.Cl.Cl
  • InChi: 1S/C26H45N15O10.3ClH/c1-31-10(2-3-32-24(27)28)4-16(44)35-12-6-33-23(50)18(11-5-17(45)40-25(29)39-11)41-20(47)13(7-34-26(30)51)36-21(48)14(8-42)38-22(49)15(9-43)37-19(12)46;;;/h7,10-12,14-15,17-18,31,42-43,45H,2-6,8-9H2,1H3,(H,33,50)(H,35,44)(H,36,48)(H,37,46)(H,38,49)(H,41,47)(H4,27,28,32)(H3,29,39,40)(H3,30,34,51);3*1H/b13-7-;;;
  • InChiKey: ZIKSIUDXAHDGBQ-KSBLBTQISA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(10Z)-10-[(aminocarbonylamino)methylidene]-13-(2-azanyl-4-hydroxy-1,4,5,6-tetrahydropyrimidin-6-yl)-4,7-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-3,6,9,12,15-pentazacyclohexadec-1-yl]-5-[bis(azanyl)methylideneamino]-3-(methylamino)pentanamide trihydrochloride
  • N-[(10Z)-13-(2-amino-4-hydroxy-1,4,5,6-tetrahydropyrimidin-6-yl)-2,5,8,11,14-pentaketo-4,7-dimethylol-10-(ureidomethylene)-3,6,9,12,15-pentazacyclohexadec-1-yl]-5-guanidino-3-(methylamino)valeramide trihydrochloride
  • N-[(10Z)-13-(2-amino-4-hydroxy-1,4,5,6-tetrahydropyrimidin-6-yl)-10-[(carbamoylamino)methylidene]-4,7-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-3,6,9,12,15-pentazacyclohexadec-1-yl]-5-(diaminomethylideneamino)-3-(methylamino)pentanamide trihydrochloride
  • LL-BM 547
  • N-[(6Z)-3-(2-amino-6-hydroxy-3,4,5,6-tetrahydropyrimidin-4-yl)-6-[(carbamoylamino)methylidene]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclohexadec-15-yl]-5-(diaminomethylideneamino)-3-methylaminopentanamide trihydrochloride
  • N-[(6Z)-3-(2-amino-6-hydroxy-3,4,5,6-tetrahydropyrimidin-4-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-15-yl]-5-guanidino-3-methylamino-pentanamide trihydrochloride
  • N-[(6Z)-3-(2-amino-6-hydroxy-3,4,5,6-tetrahydropyrimidin-4-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-15-yl]-5-guanidino-3-methylaminopentanamide trihydrochloride
  • N-[(6Z)-3-(2-amino-6-hydroxy-3,4,5,6-tetrahydropyrimidin-4-yl)-2,5,8,11,14-pentaketo-9,12-dimethylol-6-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-15-yl]-5-guanidino-3-methylamino-valeramide trihydrochloride
  • N-[(6Z)-6-[(aminocarbonylamino)methylidene]-3-(2-amino-6-hydroxy-3,4,5,6-tetrahydropyrimidin-4-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclohexadec-15-yl]-5-(diaminomethylideneamino)-3-methylamino-pentanamide trihydrochloride
  • 61473-86-7
  • LL BM547
  • LL-BM-547
  • Viomycin, 1-(5-((aminoiminomethyl)amino)-L-3-(methylamino)pentanoic acid)-, trihydrochloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0464 0.1293
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0081 0.0669 0.1285
Schistosoma mansoni DNA polymerase eta 0.0175 0.1589 0.2391
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0024 0.0108 0.0207
Schistosoma mansoni DNA helicase recq1 0.0042 0.0283 0.0426
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Echinococcus multilocularis flap endonuclease 1 0.0058 0.0443 0.0566
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0053 0.0399 0.06
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.007 0.0558 0.0558
Brugia malayi ThiF family protein 0.0053 0.0399 0.1111
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0229 0.0229
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Plasmodium vivax flap endonuclease 1, putative 0.0058 0.0443 0.1234
Onchocerca volvulus 0.005 0.0367 0.1388
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0054 0.0082
Entamoeba histolytica phosphoglycerate kinase, putative 0.0379 0.359 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0037 0.0234 0.0234
Echinococcus granulosus GPCR family 2 0.0018 0.0055 0.0083
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0115 0.0998 0.1275
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0356 0.1348
Brugia malayi 6-phosphofructokinase 0.025 0.2328 0.6485
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0024 0.0108 0.0138
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0154
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0035 0.022 0.0598
Loa Loa (eye worm) hypothetical protein 0.0054 0.0407 0.1134
Trypanosoma cruzi DNA polymerase eta, putative 0.0175 0.1589 0.1589
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0022 0.0022
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0118 0.1033 0.1555
Loa Loa (eye worm) beta-lactamase 0.0041 0.0279 0.0777
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0151
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0022 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0673 0.1875
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Onchocerca volvulus 0.0279 0.2609 1
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0054 0.0082
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0018
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0054 0.0082
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0464 0.1088
Schistosoma mansoni hypothetical protein 0.0488 0.4657 0.7008
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0138
Trypanosoma brucei phosphoglycerate kinase, putative 0.0139 0.1238 0.1238
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0277 0.0417
Giardia lamblia Sgs1 DNA helicase, putative 0.0042 0.0283 0.0753
Brugia malayi mbt repeat family protein 0.0048 0.0342 0.0954
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0236 0.0355
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0054 0.0403 0.0403
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0279 0.0777
Trypanosoma brucei unspecified product 0.0081 0.0673 0.0673
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0115 0.0998 0.1502
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0238 0.0663
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0005 0.0014
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0549 0.0826
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0537 0.1497
Trypanosoma cruzi DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Plasmodium falciparum phosphoglycerate kinase 0.0379 0.359 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0108 0.03
Schistosoma mansoni voltage-gated cation channel 0.0115 0.0998 0.1502
Brugia malayi mbt repeat family protein 0.0048 0.0342 0.0954
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0024 0.0108 0.0207
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0342 0.0515
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.2835 0.7897
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1922 0.5352
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0022 0.0022
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0549 0.0701
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0407 0.0613
Trichomonas vaginalis dullard protein, putative 0.0014 0.0014 0.0038
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0279 0.0535
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0024 0.0108 0.0108
Echinococcus granulosus Chromobox protein 3 0.0013 0.0005 0.0008
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0005 0.0014
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.027 0.0753
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0115 0.0998 0.278
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0005 0.00000000047003
Loa Loa (eye worm) MBCTL1 0.0054 0.0407 0.1134
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0081 0.0669 0.1285
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0054 0.0151
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.027 0.0753
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0068 0.0537 0.0221
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.027 0.0753
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.025 0.2328 0.4471
Schistosoma mansoni flap endonuclease-1 0.0052 0.0388 0.0584
Schistosoma mansoni alpha glucosidase 0.004 0.027 0.0407
Brugia malayi jmjC domain containing protein 0.0018 0.0054 0.0151
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.011 0.0306
Plasmodium vivax acyl-CoA synthetase, putative 0.0061 0.0468 0.1304
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0811 0.7831 1
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0024 0.0108 0.03
Trichomonas vaginalis flap endonuclease-1, putative 0.0058 0.0443 0.1234
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0138
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0446 0.1242
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0279 0.0777
Loa Loa (eye worm) hypothetical protein 0.0024 0.011 0.0306
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0279 0.0535
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0436 0.0837
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0464 0.0891
Entamoeba histolytica acyl-CoA synthetase, putative 0.0081 0.0669 0.1864
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0277 0.0771
Onchocerca volvulus 0.0024 0.0108 0.0394
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.0873 0.1314
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.1659 0.2118
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0034
Giardia lamblia Fructose-bisphosphate aldolase 0.0324 0.3055 0.8503
Entamoeba histolytica deoxycytidyl transferase, putative 0.0118 0.1033 0.2878
Brugia malayi Protein kinase domain containing protein 0.0018 0.005 0.0138
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0024 0.0108 0.03
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0083 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Trichomonas vaginalis dullard protein, putative 0.0014 0.0014 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0367 0.0552
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0279 0.0777
Brugia malayi jmjC domain containing protein 0.0071 0.0568 0.1581
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0024 0.0037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0379 0.359 0.359
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0024 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0081 0.0226
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0054 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.2835 0.7897
Brugia malayi M-phase phosphoprotein, mpp8 0.0013 0.0005 0.0014
Brugia malayi 6-phosphofructokinase 0.025 0.2328 0.6485
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0042 0.0283 0.0775
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0356 0.0992
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0108 0.0108
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0014
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0089 0.0744 0.2061
Plasmodium vivax heterochromatin protein 1, putative 0.0013 0.0005 0.0014
Leishmania major phosphoglycerate kinase B, cytosolic 0.0379 0.359 0.359
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0407 0.052
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0054 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Treponema pallidum phosphoglycerate kinase 0.0379 0.359 1
Loa Loa (eye worm) calcium channel 0.0115 0.0998 0.278
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0279 0.0279
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0053 0.0399 0.1099
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.002 0.0075 0.0208
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0005 0.0008
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0014 0.0014 0.0014
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0158 0.1428 0.3978
Trichomonas vaginalis dullard protein, putative 0.0014 0.0014 0.0038
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0005 0.0014
Echinococcus granulosus voltage dependent calcium channel 0.0115 0.0998 0.1502
Schistosoma mansoni SET domain protein 0.0016 0.003 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0002 0.0004
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0068 0.0537 0.1296
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0008
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0277 0.0277
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0024 0.0108 0.03
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0537 0.1497
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0108 0.0207
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.025 0.2328 0.2328
Mycobacterium tuberculosis Conserved protein 0.0041 0.0279 0.0535
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0133 0.1177 0.226
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0379 0.359 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0234 0.0652
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0669 0.1285
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0277 0.0771
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0054 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0537 0.1497
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0022 0.0061
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0158 0.1428 0.2742
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0042 0.0283 0.0426
Brugia malayi RNA binding protein 0.015 0.1341 0.3736
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.027 0.027
Onchocerca volvulus 0.0017 0.0037 0.0123
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0283 0.0788
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0669 0.1285
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0022 0.0061
Loa Loa (eye worm) phosphofructokinase 0.025 0.2328 0.6485
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0024 0.0108 0.03
Trypanosoma brucei phosphoglycerate kinase 0.0379 0.359 0.359
Mycobacterium leprae Probable lipase LipE 0.0041 0.0279 0.0777
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0024 0.0108 0.0207
Echinococcus multilocularis voltage dependent calcium channel 0.0115 0.0998 0.1275
Echinococcus granulosus lysosomal alpha glucosidase 0.0182 0.1659 0.2496
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0102 0.0873 0.2432
Entamoeba histolytica hypothetical protein 0.0013 0.0005 0.0014
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0046 0.0128
Echinococcus granulosus dnaJ subfamily B 0.0488 0.4657 0.7008
Echinococcus granulosus geminin 0.0386 0.3661 0.5509
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0068 0.0537 0.1497
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0277 0.0353
Entamoeba histolytica hypothetical protein 0.0081 0.0673 0.1873
Loa Loa (eye worm) hypothetical protein 0.0379 0.359 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Onchocerca volvulus Glucosylceramidase homolog 0.0198 0.1817 0.6957
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0133 0.1177 0.1177
Brugia malayi hypothetical protein 0.0013 0.0005 0.0014
Toxoplasma gondii 6-phosphofructokinase 0.0068 0.0537 0.1497
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0081 0.0226
Echinococcus granulosus MAM 0.0018 0.005 0.0075
Schistosoma mansoni microtubule-associated protein tau 0.069 0.6646 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0238 0.0663
Trypanosoma brucei chrX additional, unordered contigs 0.0037 0.0234 0.0234
Leishmania major 4-coumarate:coa ligase-like protein 0.0081 0.0669 0.0669
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0342 0.0954
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0115 0.0998 0.1275
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0277 0.0417
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0055 0.0154
Echinococcus granulosus neuropeptide receptor A26 0.0449 0.4281 0.6443
Trichomonas vaginalis DNA polymerase eta, putative 0.0177 0.1614 0.4495
Loa Loa (eye worm) glutaminase 0.031 0.2912 0.8112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0436 0.0837
Brugia malayi Muscle positioning protein 4 0.0017 0.0037 0.0104
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.027 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Trypanosoma brucei unspecified product 0.0163 0.147 0.147
Echinococcus multilocularis Chromo domain 0.0013 0.0005 0.0007
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0115 0.0998 0.1275
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0277 0.0417
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.025 0.2328 0.6402
Leishmania major ATP-dependent phosphofructokinase 0.025 0.2328 0.2328
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0042 0.0283 0.0788
Brugia malayi Phosphoglycerate kinase 0.0379 0.359 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0081 0.0669 0.1285
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.1298 0.1298
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Trichomonas vaginalis phosphofructokinase, putative 0.025 0.2328 0.6485
Trypanosoma brucei glucosidase, putative 0.004 0.027 0.027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0544 0.5208 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0283 0.0788
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0049 0.0351 0.0528
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0379 0.359 0.359
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0669 0.1864
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.0873 0.1115
Entamoeba histolytica phosphofructokinase, putative 0.025 0.2328 0.6485
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0489 0.4667 0.4667
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0108 0.03
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.025 0.2328 0.6485
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0061
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.027 0.0753
Loa Loa (eye worm) TK/ALK protein kinase 0.0018 0.005 0.0138
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0379 0.359 0.6894
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0055 0.0154
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0108 0.0207
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0014 0.0038
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0302 0.2835 0.7897
Entamoeba histolytica recQ family helicase, putative 0.0054 0.0403 0.1123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0081 0.0226
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0279 0.0777
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0073 0.011
Schistosoma mansoni chromobox protein 0.0013 0.0005 0.0008
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0279 0.0777
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0055 0.0083
Trypanosoma brucei DNA polymerase IV, putative 0.0177 0.1614 0.1614
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0568 0.1581
Trypanosoma cruzi ubiquitin-activating enzyme-like protein 0.0017 0.0038 0.0038
Schistosoma mansoni amyloid beta A4 protein related 0.0082 0.0678 0.102
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0024 0.0108 0.0207
Loa Loa (eye worm) RecQ helicase 0.0101 0.0864 0.2408
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.2835 0.7897
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0024 0.0108 0.0207
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0537 0.1497
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0054 0.0069
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0108 0.03
Echinococcus multilocularis expressed protein 0.0037 0.0238 0.0304
Mycobacterium ulcerans hypothetical protein 0.0037 0.0234 0.0449
Loa Loa (eye worm) hypothetical protein 0.015 0.1341 0.3736
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0263 0.2458 0.472
Schistosoma mansoni hypothetical protein 0.0302 0.2839 0.4272
Onchocerca volvulus 0.0017 0.0037 0.0123
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0115 0.0998 0.1275
Echinococcus multilocularis neuropeptide receptor A26 0.0449 0.4281 0.5467
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0056
Loa Loa (eye worm) hypothetical protein 0.0048 0.0342 0.0954
Leishmania major DNA polymerase kappa, putative 0.0133 0.1177 0.1177
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0815 0.0815
Brugia malayi jmjC domain containing protein 0.0018 0.0054 0.0151
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0177 0.161 0.161
Brugia malayi jmjC domain containing protein 0.0069 0.0549 0.1528
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0024 0.0108 0.0207
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0277 0.0735
Leishmania major hypothetical protein, conserved 0.0041 0.0279 0.0279
Mycobacterium tuberculosis Conserved protein 0.0041 0.0279 0.0535
Schistosoma mansoni 6-phosphofructokinase 0.025 0.2328 0.3504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0229 0.0639
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0068 0.0544 0.1515
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.0873 0.1314
Echinococcus granulosus expressed protein 0.0037 0.0238 0.0358
Giardia lamblia DNA damage repair protein 0.0037 0.0234 0.0616
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0464 0.1293
Loa Loa (eye worm) 6-phosphofructokinase 0.025 0.2328 0.6485
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0024 0.0108 0.0207
Brugia malayi Phosphoglycerate kinase 0.0139 0.1238 0.3449
Onchocerca volvulus 0.0024 0.0108 0.0394
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.027 0.0753
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0054 0.0069
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.027 0.0753
Schistosoma mansoni cpg binding protein 0.0034 0.021 0.0316
Loa Loa (eye worm) hypothetical protein 0.0017 0.0037 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Trypanosoma brucei DNA polymerase eta, putative 0.0175 0.1589 0.1589
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0108 0.03
Entamoeba histolytica acyl-CoA synthetase, putative 0.0081 0.0669 0.1864
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0265 0.0738
Schistosoma mansoni hypothetical protein 0.0386 0.3661 0.5509
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0818 0.0818
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0054 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0279 0.0279
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0489 0.4667 0.4667
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0039 0.0253 0.0381
Echinococcus multilocularis amyloid beta A4 protein 0.0082 0.0678 0.0865
Plasmodium falciparum flap endonuclease 1 0.0058 0.0443 0.1221
Leishmania major alpha glucosidase II subunit, putative 0.004 0.027 0.027
Plasmodium vivax SET domain protein, putative 0.0037 0.0236 0.0657
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0669 0.1864
Brugia malayi Valyl-tRNA synthetase 0.0013 0.0005 0.0014
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0068 0.0537 0.1497
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.025 0.2328 0.2328
Mycobacterium ulcerans DNA polymerase IV 0.0177 0.1614 0.3098
Onchocerca volvulus 0.0041 0.0279 0.1051
Plasmodium falciparum acyl-CoA synthetase 0.0061 0.0468 0.1292
Brugia malayi jmjC domain containing protein 0.0018 0.0054 0.0151
Echinococcus multilocularis Eukaryotic translation initiation factor 4H 0.015 0.1341 0.1713
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0014 0.0014 0.0024
Giardia lamblia Flap structure-specific endonuclease 0.0058 0.0443 0.12
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0279 0.0535
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0035 0.022 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0139 0.1238 0.1238
Trichomonas vaginalis esterase, putative 0.0041 0.0279 0.0777
Entamoeba histolytica acyl-coA synthetase, putative 0.0081 0.0669 0.1864
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.027 0.0407
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0053 0.0399 0.06
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0115 0.0998 0.1502
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0379 0.359 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0277 0.0353
Trichomonas vaginalis glutaminase, putative 0.031 0.2912 0.8112
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0229 0.0229
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0083 0.0124
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0277 0.0771
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0022 0.0061
Schistosoma mansoni chromobox protein 0.0013 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0079 0.0646 0.18
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0014 0.0038
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0236 0.0301
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.1659 0.2118
Onchocerca volvulus 0.0048 0.0342 0.1295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.0873 0.1314
Loa Loa (eye worm) flap endonuclease-1 0.0058 0.0443 0.1234
Loa Loa (eye worm) DOMON domain-containing protein 0.0017 0.0037 0.0104
Loa Loa (eye worm) X11 protein 0.0082 0.0678 0.1887
Echinococcus multilocularis 6 phosphofructokinase 0.025 0.2328 0.2973
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0464 0.1259
Trichomonas vaginalis set domain proteins, putative 0.0279 0.2609 0.7268
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0818 0.0818
Leishmania major acetyl-CoA synthetase, putative 0.0024 0.0108 0.0108
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.027 0.0753
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0081 0.0669 0.1285
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0279 0.0777
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0549 0.0701
Onchocerca volvulus 0.0013 0.0005 0.000000055043
Echinococcus multilocularis phosphoglycerate kinase 1 0.0379 0.359 0.4585
Trypanosoma brucei phosphoglycerate kinase 0.0139 0.1238 0.1238
Brugia malayi jmjC domain containing protein 0.0018 0.0054 0.0151
Trichomonas vaginalis phosphofructokinase, putative 0.025 0.2328 0.6485
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0115 0.0998 0.1502
Trypanosoma brucei DNA damage repair protein, putative 0.0037 0.0234 0.0234
Giardia lamblia Phosphoglycerate kinase 0.0379 0.359 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Toxoplasma gondii ThiF family protein 0.0035 0.022 0.0612
Loa Loa (eye worm) hypothetical protein 0.0021 0.0081 0.0226
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0054 0.0082
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0081 0.0669 0.1864
Loa Loa (eye worm) hypothetical protein 0.0115 0.0998 0.278
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0081 0.0226
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.2835 0.7897
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0108 0.0207
Echinococcus multilocularis dna polymerase eta 0.0175 0.1589 0.2029
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0118 0.1033 0.1319
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0005 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0279 0.0777
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0342 0.0515
Echinococcus multilocularis voltage dependent calcium channel 0.0115 0.0998 0.1275
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0068 0.0537 0.1464
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0407 0.1134
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0005 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.025 0.2328 0.6485
Schistosoma mansoni SET domain protein 0.0039 0.0253 0.0381
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.027 0.0753
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0322 0.1217
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0324 0.3055 0.8509
Onchocerca volvulus 0.0024 0.0108 0.0394
Loa Loa (eye worm) helicase 0.0013 0.0005 0.0014
Loa Loa (eye worm) oxidoreductase 0.0024 0.0108 0.03
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0054 0.0403 0.0403
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0024 0.0037
Entamoeba histolytica hypothetical protein 0.0013 0.0005 0.0014
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0229 0.0229
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0302 0.2835 0.7897
Entamoeba histolytica phosphofructokinase, putative 0.025 0.2328 0.6485
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0035 0.022 0.028
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0005 0.0014
Toxoplasma gondii ABC1 family protein 0.0041 0.0279 0.0777
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0038
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0014 0.0014 0.0021
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0139 0.1238 0.1238
Loa Loa (eye worm) hypothetical protein 0.0024 0.0108 0.03
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0669 0.1864
Echinococcus granulosus Eukaryotic translation initiation factor 4H 0.015 0.1341 0.2019
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0777
Brugia malayi SEA domain containing protein 0.0017 0.0037 0.0104
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0054 0.0403 0.0403
Mycobacterium ulcerans DNA polymerase IV 0.0177 0.1614 0.3098
Echinococcus granulosus dna polymerase kappa 0.0177 0.1614 0.2428
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0138
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0342 0.1295
Schistosoma mansoni DNA polymerase IV / kappa 0.0037 0.0234 0.0352
Trypanosoma brucei unspecified product 0.0081 0.0673 0.0673
Mycobacterium ulcerans hypothetical protein 0.0041 0.0279 0.0535
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0014 0.0011 0.0016
Brugia malayi beta-lactamase 0.0041 0.0279 0.0777
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0022 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.0873 0.1314
Schistosoma mansoni hypothetical protein 0.0386 0.3661 0.5509
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0068 0.0537 0.1485
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0464 0.1293
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0014 0.0014 0.0038
Leishmania major pantothenate kinase subunit, putative 0.0015 0.0026 0.0026
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0379 0.359 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Schistosoma mansoni hypothetical protein 0.0018 0.005 0.0075
Echinococcus granulosus cpg binding protein 0.0036 0.0229 0.0345
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0024 0.0108 0.03
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0489 0.4667 0.4667
Loa Loa (eye worm) 6-phosphofructokinase 0.025 0.2328 0.6485
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0042 0.0283 0.0361
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Schistosoma mansoni chromobox protein 0.0081 0.0673 0.1013
Entamoeba histolytica hypothetical protein 0.0081 0.0673 0.1873
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0234 0.0234
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0014 0.0014 0.0018
Toxoplasma gondii hypothetical protein 0.0021 0.0081 0.0226
Schistosoma mansoni glutaminase 0.031 0.2912 0.4383
Entamoeba histolytica Flap nuclease, putative 0.0058 0.0443 0.1234
Leishmania major DNA polymerase kappa, putative 0.0037 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0036 0.0225 0.0628
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0342 0.0437
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Brugia malayi Flap endonuclease-1 0.0058 0.0443 0.1234
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0061 0.0468 0.0899
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0436 0.0837
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.027 0.0345
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0054 0.0054
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0407 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0322 0.0897
Echinococcus multilocularis chromobox protein 1 0.0081 0.0673 0.086
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0115 0.0998 0.1502
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0356 0.0992
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0446 0.1242
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0279 0.0279
Giardia lamblia DINP protein human, muc B family 0.0133 0.1177 0.3253
Loa Loa (eye worm) hypothetical protein 0.004 0.0265 0.0738
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0003 0.0004
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.015 0.1341 0.2019
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0039 0.0253 0.0323
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0005 0.0008
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0145 0.1298 0.1298
Brugia malayi ImpB/MucB/SamB family protein 0.0175 0.1589 0.4427
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0537 0.1497
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0277 0.0277
Trichomonas vaginalis DNA helicase recq, putative 0.0101 0.0864 0.2408
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0177 0.1614 0.4495
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0054 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0054 0.0082
Plasmodium vivax 6-phosphofructokinase, putative 0.0068 0.0537 0.1497
Mycobacterium ulcerans beta-lactamase 0.0041 0.0279 0.0535
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0014 0.0014
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0054 0.0082
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0277 0.0277
Onchocerca volvulus 0.0041 0.0279 0.1051
Entamoeba histolytica hypothetical protein 0.0081 0.0673 0.1873
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0611 0.092
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0051 0.0378 0.1053
Onchocerca volvulus 0.0017 0.0037 0.0123
Chlamydia trachomatis phosphoglycerate kinase 0.0379 0.359 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Brugia malayi hypothetical protein 0.0081 0.0673 0.1873
Leishmania major hypothetical protein, conserved 0.0018 0.0054 0.0054
Plasmodium vivax DNA repair protein REV1, putative 0.0037 0.0234 0.0652
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0022 0.0061
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0022 0.0061
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0005 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0073 0.0094
Trichomonas vaginalis hypothetical protein 0.0013 0.0005 0.0014
Onchocerca volvulus 0.0024 0.0108 0.0394
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0014
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0446 0.1242
Entamoeba histolytica hypothetical protein 0.0081 0.0673 0.1873
Mycobacterium ulcerans lipase LipD 0.0041 0.0279 0.0535
Echinococcus multilocularis sodium channel protein 0.0049 0.0351 0.0448
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0054 0.0151
Plasmodium vivax acetyl-CoA synthetase, putative 0.0024 0.0108 0.03
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0115 0.0998 0.1502
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0015 0.0018 0.0035
Echinococcus granulosus chromobox protein 1 0.0081 0.0673 0.1013
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0068 0.0537 0.1485
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0024 0.0108 0.0108
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0081 0.0673 0.0859
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0083
Brugia malayi hypothetical protein 0.0018 0.005 0.0138
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0083
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0024 0.0108 0.0207
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0024 0.0068
Schistosoma mansoni phosphoglycerate kinase 0.0379 0.359 0.5402
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0283 0.0788
Brugia malayi ThiF family protein 0.0035 0.022 0.0612
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0279 0.0535
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.027 0.0753
Entamoeba histolytica hypothetical protein 0.0013 0.0005 0.0014
Schistosoma mansoni ap endonuclease 0.006 0.0464 0.0699
Trypanosoma brucei DNA damage repair protein, putative 0.0037 0.0234 0.0234
Trichomonas vaginalis antibiotic synthetase, putative 0.0024 0.0108 0.03
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0015 0.0026 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.147 0.147
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0322 0.0897
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0061 0.0468 0.1304
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0464 0.1293
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0342 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0191 0.0533
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.027 0.0753
Schistosoma mansoni cpg binding protein 0.0036 0.0229 0.0345
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0108 0.0108
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0022 0.0061
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0118 0.1033 0.1555
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.1033 0.1984
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0236 0.0301
Schistosoma mansoni alpha-glucosidase 0.0157 0.141 0.2122
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0035 0.022 0.033
Plasmodium vivax 6-phosphofructokinase, putative 0.0068 0.0537 0.1497
Trypanosoma cruzi DNA damage repair protein, putative 0.0037 0.0234 0.0234
Echinococcus multilocularis neuropeptide s receptor 0.0449 0.4281 0.5467
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.021 0.0586
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0234 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Schistosoma mansoni hypothetical protein 0.0018 0.005 0.0075
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0024 0.0108 0.0207
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0464 0.0464
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0096 0.0815 0.2269
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0083 0.0083
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0139 0.1238 0.1238
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0054 0.0082
Entamoeba histolytica recQ family DNA helicase 0.0021 0.0083 0.023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.027 0.0753
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0777
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0017 0.0038 0.0106
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0068 0.0537 0.1497
Echinococcus multilocularis chromobox protein 1 0.0081 0.0673 0.086
Schistosoma mansoni cpg binding protein 0.0036 0.0229 0.0345
Loa Loa (eye worm) hypothetical protein 0.0081 0.0669 0.1864
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0229 0.0229
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0053 0.0399 0.1111
Echinococcus multilocularis cpg binding protein 0.0036 0.0229 0.0293
Trichomonas vaginalis rotamase, putative 0.0036 0.0229 0.0639
Loa Loa (eye worm) hypothetical protein 0.0061 0.0468 0.1304
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0046 0.0128
Leishmania major 4-coumarate:coa ligase-like protein 0.0081 0.0669 0.0669
Mycobacterium tuberculosis Conserved protein 0.0041 0.0279 0.0535
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0279 0.042
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0083 0.023
Echinococcus multilocularis chromobox protein 2 0.0013 0.0005 0.0007
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0068 0.0537 0.0221
Leishmania major ubiquitin-activating enzyme-like protein 0.0035 0.022 0.022
Onchocerca volvulus 0.0036 0.0225 0.0846
Echinococcus granulosus flap endonuclease 1 0.0058 0.0443 0.0667
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0464 0.0464
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0005 0.0014
Brugia malayi chromobox protein homolog 3 0.0046 0.0322 0.0897
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0277 0.0417
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0277 0.0277
Onchocerca volvulus 0.0017 0.0037 0.0123
Toxoplasma gondii phosphofructokinase PFKII 0.0068 0.0537 0.1497
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0042 0.0283 0.0426
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0058 0.0446 0.1242
Mycobacterium ulcerans 6-phosphofructokinase 0.025 0.2328 0.4471
Onchocerca volvulus 0.0018 0.005 0.0171
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0024 0.0108 0.0162
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0279 0.0777
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0182 0.1659 0.462
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0024 0.0108 0.03
Toxoplasma gondii hypothetical protein 0.0167 0.1508 0.4199
Loa Loa (eye worm) hypothetical protein 0.0017 0.0037 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0133 0.1177 0.1177
Brugia malayi SET domain containing protein 0.0017 0.0037 0.0103
Loa Loa (eye worm) hypothetical protein 0.0041 0.0277 0.0771
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0535 0.1491
Onchocerca volvulus 0.0081 0.0669 0.255
Entamoeba histolytica phosphofructokinase, putative 0.025 0.2328 0.6485
Brugia malayi beta-lactamase family protein 0.0041 0.0279 0.0777
Schistosoma mansoni phosphoglycerate kinase 0.0379 0.359 0.5402
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0279 0.042
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.027 0.0753
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0464 0.0464
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0055 0.0083
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.015 0.1341 0.2019
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0035 0.022 0.0612
Echinococcus multilocularis GPCR, family 2 0.0018 0.0055 0.0071
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0035 0.022 0.033
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0568 0.0854
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0279 0.0535
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0277 0.0417
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0014
Onchocerca volvulus 0.0041 0.0279 0.1051
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0075 0.0145
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0024 0.0108 0.0207
Echinococcus granulosus endonuclease exonuclease phosphatase 0.02 0.1838 0.2766
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0108 0.0108
Brugia malayi Pre-SET motif family protein 0.0037 0.0236 0.0657
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0818 0.0818
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0024 0.0108 0.0207
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0118 0.1033 0.2878
Trypanosoma cruzi DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0081 0.0669 0.1864
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.004 0.0112
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0464 0.1293
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0024 0.0108 0.0108
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0279 0.0535
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0014 0.0021
Brugia malayi Protein cec-1. 0.0013 0.0005 0.0014
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0245 0.228 0.635
Trichomonas vaginalis DNA helicase recq, putative 0.0054 0.0403 0.1123
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0014 0.0038
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0024 0.0108 0.0207
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0014 0.0021
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0379 0.359 1
Brugia malayi phosphofructokinase 0.025 0.2328 0.6485
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0379 0.359 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0236 0.0355
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.007 0.0558 0.0558
Echinococcus granulosus chromobox protein 2 0.0013 0.0005 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0342 0.0515
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0055 0.0071
Onchocerca volvulus 0.0017 0.0037 0.0123
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0022 0.0022
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0014 0.0011 0.0013
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0283 0.0788
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1032 1 1
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0777
Leishmania major DNA polymerase eta, putative 0.0175 0.1589 0.1589
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0238 0.0663
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0673 0.1875
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0669 0.1285
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0081 0.0226
Entamoeba histolytica recQ family helicase, putative 0.002 0.0075 0.0208
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0279 0.0535
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Giardia lamblia Ubiquitin-activating enzyme E1 1 0.0017 0.0038 0.0068
Trichomonas vaginalis rotamase, putative 0.0037 0.0238 0.0663
Toxoplasma gondii exonuclease III APE 0.006 0.0464 0.1293
Trypanosoma cruzi DNA polymerase eta, putative 0.0093 0.079 0.079
Schistosoma mansoni hypothetical protein 0.004 0.0265 0.0399
Mycobacterium ulcerans hypothetical protein 0.0081 0.0669 0.1285
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0054 0.0054
Trypanosoma brucei phosphoglycerate kinase 0.0379 0.359 0.359
Echinococcus multilocularis geminin 0.0386 0.3661 0.4675
Loa Loa (eye worm) hypothetical protein 0.0037 0.0236 0.0657
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0673 0.1875
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0277 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.015 0.1341 0.2019
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0054 0.0151
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0139 0.1238 0.1238
Schistosoma mansoni hypothetical protein 0.0081 0.0673 0.1012
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0058 0.0443 0.0443
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.027 0.0753
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0073 0.0593 0.1651
Onchocerca volvulus 0.0105 0.0906 0.346
Schistosoma mansoni DNA helicase recq5 0.0042 0.0283 0.0426
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.1922 0.5352
Brugia malayi Heterochromatin protein 1 0.0081 0.0673 0.1875
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0005 0.0014
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0815 0.0815
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.02 0.1838 0.2347
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0058 0.0443 0.0443
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0139 0.1238 0.1238
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0081 0.0226
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0014
Treponema pallidum fructose-bisphosphate aldolase 0.0324 0.3055 0.8474
Brugia malayi beta-lactamase family protein 0.0041 0.0279 0.0777
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0436 0.0837
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0053 0.0399 0.0509
Loa Loa (eye worm) hypothetical protein 0.0081 0.0669 0.1864
Echinococcus granulosus phd:f box containing protein 0.0018 0.0054 0.0082
Brugia malayi CHD4 protein 0.0015 0.0024 0.0068
Schistosoma mansoni acetyl-CoA synthetase 0.0024 0.0108 0.0162
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0279 0.0356
Schistosoma mansoni chromobox protein 0.0081 0.0673 0.1013
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0093 0.079 0.2201
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0058 0.0443 0.0443
Mycobacterium ulcerans glutaminase 0.031 0.2912 0.5592
Schistosoma mansoni ap endonuclease 0.006 0.0464 0.0699
Echinococcus granulosus microtubule associated protein 2 0.069 0.6646 1
Schistosoma mansoni blooms syndrome DNA helicase 0.008 0.0656 0.0987
Leishmania major acetyl-CoA synthetase, putative 0.0024 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0024 0.0108 0.03
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0537 0.1497
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.2835 0.7897
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0407 0.0613
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.003 0.0171 0.0171
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0024 0.0108 0.0286
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0042 0.0283 0.0361
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0236 0.0657
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0067 0.0536 0.1493
Plasmodium vivax phosphoglycerate kinase, putative 0.0379 0.359 1
Loa Loa (eye worm) hypothetical protein 0.0175 0.1589 0.4427
Trichomonas vaginalis antibiotic synthetase, putative 0.0024 0.0108 0.03
Plasmodium falciparum DNA repair protein REV1, putative 0.0037 0.0234 0.0638
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0342 0.0515
Plasmodium vivax JmjC domain containing protein 0.0018 0.0054 0.0151
Brugia malayi polk-prov protein 0.0096 0.0815 0.2269
Echinococcus multilocularis microtubule associated protein 2 0.069 0.6646 0.8486
Trypanosoma brucei DNA polymerase IV, putative 0.0177 0.1614 0.1614
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0022 0.0061
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0407 0.0613
Loa Loa (eye worm) glutaminase 2 0.031 0.2912 0.8112
Trypanosoma cruzi DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Mycobacterium ulcerans acetyl-CoA synthetase 0.0024 0.0108 0.0207
Echinococcus granulosus CTD small phosphatase protein like 0.0014 0.0014 0.0021
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0108 0.0207
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0005 0.0007
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.011 0.0306
Loa Loa (eye worm) hypothetical protein 0.0061 0.0468 0.1304
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.1817 0.5061
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0568 0.0854
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0014 0.0038
Trichomonas vaginalis DNA helicase recq1, putative 0.0101 0.0864 0.2408
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0054 0.0082
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0139 0.1238 0.1238
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0061 0.0468 0.0899
Brugia malayi ImpB/MucB/SamB family protein 0.0118 0.1033 0.2878
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0145 0.1298 0.1298
Toxoplasma gondii propionate-CoA ligase 0.0024 0.0108 0.03
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0464 0.1281
Leishmania major DNA polymerase eta, putative 0.0093 0.079 0.079
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0158 0.1428 0.2742
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0191 0.0533
Loa Loa (eye worm) hypothetical protein 0.0061 0.0468 0.1304
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0549 0.0826
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0035 0.022 0.022
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0055 0.0071
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0024 0.0108 0.0207
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.027 0.0753
Onchocerca volvulus 0.0018 0.005 0.0171
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0049 0.0351 0.0528
Mycobacterium ulcerans hypothetical protein 0.0544 0.5208 1
Trichomonas vaginalis phosphofructokinase, putative 0.025 0.2328 0.6485
Schistosoma mansoni alpha-glucosidase 0.0157 0.141 0.2122
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0236 0.0355
Leishmania major 4-coumarate:coa ligase-like protein 0.0081 0.0669 0.0669
Brugia malayi Bloom's syndrome protein homolog 0.0101 0.0864 0.2408
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0108 0.03
Echinococcus granulosus bloom syndrome protein 0.0101 0.0864 0.1301
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.0873 0.1314
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0342 0.0437
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Loa Loa (eye worm) hypothetical protein 0.0021 0.0083 0.023
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Trypanosoma cruzi DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Echinococcus granulosus chromobox protein 1 0.0081 0.0673 0.1013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0081 0.0226
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0058 0.0443 0.1234
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0277 0.0771
Brugia malayi Pre-SET motif family protein 0.0245 0.228 0.635
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0283 0.0788
Brugia malayi CXXC zinc finger family protein 0.0034 0.021 0.0586
Leishmania major hypothetical protein, conserved 0.0014 0.0014 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0279 0.0535
Leishmania major phosphoglycerate kinase C, glycosomal 0.0379 0.359 0.359
Echinococcus multilocularis dnaJ subfamily B 0.0488 0.4657 0.5947
Brugia malayi Glycosyl hydrolases family 31 protein 0.0182 0.1659 0.462
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0014 0.0014 0.0038
Toxoplasma gondii hypothetical protein 0.0053 0.0399 0.1111
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0022 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0236 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0277 0.0771
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0464 0.1293
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0279 0.0535
Loa Loa (eye worm) hypothetical protein 0.0307 0.2884 0.8033
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0568 0.0854
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0464 0.0891
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0081 0.0669 0.1285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.0873 0.1115
Leishmania major DNA damage repair protein, putative 0.0037 0.0234 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0234 0.0234
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative 0.0017 0.0038 0.0106
Loa Loa (eye worm) hypothetical protein 0.0081 0.0669 0.1864
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0022 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0055 0.0154
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0003 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.0081 0.0673 0.1012
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0379 0.359 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0118 0.1033 0.1555
Echinococcus multilocularis MAM 0.0018 0.005 0.0063
Schistosoma mansoni 6-phosphofructokinase 0.025 0.2328 0.3504
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.011 0.0165
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0108 0.0207
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.2835 0.7897
Echinococcus granulosus phosphoglycerate kinase 1 0.0379 0.359 0.5402
Brugia malayi glutaminase DH11.1 0.031 0.2912 0.8112
Echinococcus granulosus 6 phosphofructokinase 0.025 0.2328 0.3504
Echinococcus granulosus neuropeptide s receptor 0.0449 0.4281 0.6443
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0108 0.03
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0024 0.0108 0.0207
Echinococcus multilocularis dna polymerase kappa 0.0177 0.1614 0.2061
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0229 0.0639
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0108 0.0207
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0279 0.0777
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0204 0.0307
Echinococcus multilocularis 0.0014 0.0014 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0081 0.0226
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0777
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0464 0.0699
Mycobacterium ulcerans phosphoglycerate kinase 0.0379 0.359 0.6894
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0014
Echinococcus multilocularis bloom syndrome protein 0.0101 0.0864 0.1104
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0014 0.0014 0.0038
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0022 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0279 0.042
Loa Loa (eye worm) ThiF family protein 0.0035 0.022 0.0612
Brugia malayi hypothetical protein 0.0079 0.0646 0.18
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1032 1 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0468 0.1304
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0102 0.0873 0.2432
Onchocerca volvulus 0.0034 0.021 0.0788
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1032 1 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0024 0.0108 0.03
Loa Loa (eye worm) hypothetical protein 0.0046 0.0322 0.0897
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0005 0.0014
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0145 0.1298 0.1298
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0.0005 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0081 0.0226
Schistosoma mansoni rotamase 0.0037 0.0238 0.0358
Echinococcus granulosus amyloid beta A4 protein 0.0082 0.0678 0.102
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0024 0.0108 0.03
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0014
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0081 0.0669 0.1285
Echinococcus granulosus dna polymerase eta 0.0175 0.1589 0.2391
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0108 0.0108
Plasmodium vivax ubiquitin activating enzyme, putative 0.0053 0.0399 0.1111
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0777
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.1614 0.1614
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0054 0.0069
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0081 0.0673 0.1012
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0464 0.0593
Echinococcus granulosus Chromo domain 0.0013 0.0005 0.0008

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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