Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Leishmania major | pyroglutamyl-peptidase I (C15 family) | Curated by TDR Targets | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | dna polymerase eta | 0.0168 | 0.0245 | 0.0245 |
Schistosoma mansoni | pyruvate kinase | 0.0103 | 0.0133 | 0.0537 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.0203 | 0.239 |
Brugia malayi | calpain family protein 1 | 0.0199 | 0.0298 | 0.3705 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0076 | 0.0087 | 0.2317 |
Schistosoma mansoni | thyroid hormone receptor | 0.0052 | 0.0045 | 0.0173 |
Brugia malayi | MH2 domain containing protein | 0.0236 | 0.0363 | 0.4519 |
Schistosoma mansoni | cpg binding protein | 0.009 | 0.011 | 0.0443 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0018 | 0.0166 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.0201 | 0.0201 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0304 | 0.0479 | 0.5633 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0072 | 0.0079 | 0.0989 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0052 | 0.0045 | 0.0045 |
Schistosoma mansoni | hypothetical protein | 0.0862 | 0.1443 | 0.5933 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0036 | 0.0018 | 0.0167 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0052 | 0.0045 | 0.0732 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.049 | 0.0801 | 0.3295 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0018 | 0.0552 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0052 | 0.0045 | 0.0527 |
Trypanosoma brucei | unspecified product | 0.0117 | 0.0158 | 0.1816 |
Brugia malayi | calpain family protein 1 | 0.0199 | 0.0298 | 0.3705 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0087 | 0.0105 | 0.3984 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0018 | 0.0197 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1855 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.004 | 0.1409 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0052 | 0.0045 | 0.0527 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0117 | 0.0158 | 0.4188 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0036 | 0.0018 | 0.0557 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0248 | 0.1012 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0249 | 0.1017 |
Echinococcus multilocularis | lamin dm0 | 0.0085 | 0.0103 | 0.0103 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.0059 | 0.0057 | 0.0057 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0067 | 0.0267 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0078 | 0.0091 | 0.1107 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.016 | 0.0231 | 0.6291 |
Trypanosoma brucei | pyroglutamyl-peptidase I, putative | 0.0519 | 0.0851 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0168 | 0.0245 | 0.3039 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0085 | 0.0103 | 0.1257 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0018 | 0.0483 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0236 | 0.0363 | 0.4536 |
Trypanosoma brucei | calpain-like protein, putative | 0.0059 | 0.0057 | 0.0629 |
Trypanosoma cruzi | ISWI complex protein | 0.003 | 0.0008 | 0.0093 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0209 | 0.0316 | 0.1299 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0036 | 0.0425 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.0199 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0052 | 0.0045 | 0.0527 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0011 | 0.0574 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0032 | 0.0011 | 0.0108 |
Echinococcus multilocularis | lamin | 0.0085 | 0.0103 | 0.0103 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0201 | 0.0819 |
Trypanosoma brucei | calpain-like protein, putative | 0.0059 | 0.0057 | 0.0629 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0245 | 0.3061 |
Echinococcus multilocularis | geminin | 0.017 | 0.0249 | 0.0249 |
Leishmania major | pyruvate kinase | 0.0103 | 0.0133 | 0.1561 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0034 | 0.0014 | 0.0047 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0018 | 0.0196 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.0801 | 1 |
Onchocerca volvulus | 0.009 | 0.011 | 0.1806 | |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.01 | 0.1251 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0052 | 0.0045 | 0.0173 |
Schistosoma mansoni | pyruvate kinase | 0.0103 | 0.0133 | 0.0537 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0034 | 0.0014 | 0.0057 |
Echinococcus multilocularis | calpain A | 0.0209 | 0.0316 | 0.0316 |
Echinococcus granulosus | dnaJ subfamily B | 0.0862 | 0.1443 | 0.5937 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0036 | 0.0018 | 0.0557 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0018 | 0.0018 |
Echinococcus multilocularis | pyruvate kinase | 0.0053 | 0.0046 | 0.0046 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0018 | 0.048 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0091 | 0.1135 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0067 | 0.0811 |
Giardia lamblia | DINP protein human, muc B family | 0.0117 | 0.0158 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0142 | 0.0201 | 0.2491 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0084 | 0.0345 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0199 | 0.0298 | 0.1218 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0018 | 0.0197 |
Loa Loa (eye worm) | pyruvate kinase | 0.0103 | 0.0133 | 0.1659 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0018 | 0.0074 |
Echinococcus multilocularis | pyruvate kinase | 0.0081 | 0.0095 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0091 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.0609 | 0.7604 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0018 | 0.0228 |
Echinococcus granulosus | cpg binding protein | 0.0098 | 0.0125 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0126 | 0.0172 | 0.0709 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0248 | 0.0384 | 0.4776 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0103 | 0.0133 | 0.3383 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0018 | 0.0483 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0018 | 0.0075 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0072 | 0.0079 | 0.4367 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0018 | 0.048 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0209 | 0.0316 | 0.129 |
Loa Loa (eye worm) | histone methyltransferase | 0.0029 | 0.0005 | 0.0064 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.0275 | 0.1131 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0036 | 0.0455 |
Echinococcus multilocularis | pyruvate kinase | 0.0053 | 0.0046 | 0.0046 |
Echinococcus granulosus | calpain A | 0.0059 | 0.0057 | 0.0236 |
Leishmania major | DNA polymerase kappa, putative | 0.0036 | 0.0018 | 0.0214 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0103 | 0.0133 | 0.3524 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0036 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Schistosoma mansoni | hypothetical protein | 0.0285 | 0.0448 | 0.1836 |
Echinococcus granulosus | calpain A | 0.0209 | 0.0316 | 0.1299 |
Schistosoma mansoni | cpg binding protein | 0.0098 | 0.0125 | 0.0506 |
Brugia malayi | Bromodomain containing protein | 0.0154 | 0.0222 | 0.2747 |
Leishmania major | DNA polymerase eta, putative | 0.0087 | 0.0105 | 0.1238 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0084 | 0.471 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0249 | 0.1017 |
Echinococcus granulosus | GPCR family 2 | 0.0078 | 0.0091 | 0.0374 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0048 | 0.0595 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.0201 | 0.0828 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0168 | 0.0245 | 0.2879 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0081 | 0.0095 | 0.1074 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0052 | 0.0045 | 0.0173 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0068 | 0.0074 | 0.5535 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.07 |
Leishmania major | hypothetical protein, conserved | 0.003 | 0.0008 | 0.0093 |
Onchocerca volvulus | 0.0085 | 0.0103 | 0.1689 | |
Echinococcus multilocularis | pyruvate kinase | 0.0053 | 0.0046 | 0.0046 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0036 | 0.014 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0103 | 0.0133 | 0.2182 |
Brugia malayi | hypoxia-induced factor 1 | 0.0308 | 0.0487 | 0.6072 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0067 | 0.0811 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0018 | 0.0064 |
Echinococcus multilocularis | GPCR, family 2 | 0.0078 | 0.0091 | 0.0091 |
Brugia malayi | calpain 7 | 0.0059 | 0.0057 | 0.0688 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0111 | 0.1382 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0168 | 0.0245 | 0.2845 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0209 | 0.0316 | 0.129 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0052 | 0.0045 | 0.0732 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0018 | 0.048 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0052 | 0.0045 | 0.0557 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0117 | 0.0158 | 0.1855 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.0128 | 0.0516 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0045 | 0.0183 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0046 | 0.0034 | 0.0399 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0117 | 0.0158 | 0.1816 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1855 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0084 | 0.0336 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.0031 | 0.0009 | 0.0082 |
Onchocerca volvulus | 0.0052 | 0.0045 | 0.0732 | |
Echinococcus multilocularis | transfer RNA-Lys | 0.0074 | 0.0083 | 0.0083 |
Brugia malayi | steroid hormone receptor | 0.0052 | 0.0045 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0024 | 0.0298 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0103 | 0.0133 | 0.1634 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.005 | 0.0042 | 0.0042 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0214 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0027 | 0.0002 | 0.0031 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0164 | 0.0238 | 0.098 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0027 | 0.0002 | 0.001 |
Leishmania major | DNA polymerase eta, putative | 0.0168 | 0.0245 | 0.2879 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0052 | 0.0045 | 0.0527 |
Echinococcus multilocularis | zinc finger protein | 0.0044 | 0.0031 | 0.0031 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0103 | 0.0133 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0164 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0052 | 0.0045 | 0.0173 |
Brugia malayi | CXXC zinc finger family protein | 0.009 | 0.011 | 0.1346 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0052 | 0.0045 | 0.0557 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0117 | 0.0158 | 0.1816 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0048 | 0.0186 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0052 | 0.0045 | 0.0557 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0067 | 0.0267 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0052 | 0.0045 | 0.0527 |
Leishmania major | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1855 |
Brugia malayi | PHD-finger family protein | 0.0055 | 0.005 | 0.0592 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0087 | 0.1027 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0052 | 0.0045 | 0.0557 |
Brugia malayi | nuclear receptor NHR-88 | 0.0052 | 0.0045 | 0.0527 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0053 | 0.0046 | 0.3292 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0532 | 0.6642 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0029 | 0.0005 | 0.0021 |
Brugia malayi | Pre-SET motif family protein | 0.0215 | 0.0326 | 0.4057 |
Trypanosoma cruzi | Cysteine peptidase, Clan CF, family C15 | 0.0519 | 0.0851 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Schistosoma mansoni | DNA polymerase eta | 0.0168 | 0.0245 | 0.0999 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.07 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0052 | 0.0045 | 0.0173 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0045 | 0.0183 |
Onchocerca volvulus | 0.0036 | 0.0018 | 0.0299 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0052 | 0.0045 | 0.0527 |
Brugia malayi | polk-prov protein | 0.0036 | 0.0018 | 0.0197 |
Loa Loa (eye worm) | pyruvate kinase | 0.0103 | 0.0133 | 0.1659 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0024 | 0.0298 |
Echinococcus multilocularis | pyruvate kinase | 0.0103 | 0.0133 | 0.0133 |
Echinococcus granulosus | single minded 2 | 0.0074 | 0.0083 | 0.034 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.7232 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0212 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0018 | 0.0065 |
Schistosoma mansoni | single-minded | 0.01 | 0.0127 | 0.0514 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0067 | 0.0811 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0214 |
Brugia malayi | bHLH-PAS transcription factor | 0.0074 | 0.0083 | 0.1003 |
Echinococcus granulosus | zinc finger protein | 0.0044 | 0.0031 | 0.0129 |
Brugia malayi | PAS domain containing protein | 0.01 | 0.0127 | 0.1562 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0052 | 0.0045 | 0.0183 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0052 | 0.0045 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0248 | 0.3099 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.01 | 0.0128 | 0.157 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0052 | 0.0045 | 0.0527 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0067 | 0.0267 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0139 | 0.0196 | 0.0196 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0629 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0248 | 0.0384 | 0.4792 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0117 | 0.0158 | 0.065 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0052 | 0.0045 | 0.0045 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.0201 | 0.0201 |
Echinococcus granulosus | neuropeptide s receptor | 0.0966 | 0.1622 | 0.6676 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0053 | 0.0046 | 0.3292 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0018 | 0.0483 |
Trypanosoma cruzi | kinesin, putative | 0.0059 | 0.0057 | 0.0674 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0052 | 0.0045 | 0.0527 |
Entamoeba histolytica | calpain large subunit domain III containing protein | 0.0059 | 0.0057 | 0.2808 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0036 | 0.0018 | 0.0167 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0091 | 0.0364 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0036 | 0.0018 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.007 | 0.0874 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0209 | 0.0316 | 0.0316 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.005 | 0.0042 | 0.0161 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.0045 | 0.0531 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0052 | 0.0045 | 0.0183 |
Mycobacterium ulcerans | hypothetical protein | 0.016 | 0.0231 | 1 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0308 | 0.0487 | 0.6084 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.017 | 0.0248 | 0.3078 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0091 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0059 | 0.0057 | 0.0226 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0167 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0048 | 0.0196 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0041 | 0.0027 | 0.0109 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0036 | 0.014 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.455 |
Echinococcus multilocularis | musashi | 0.0085 | 0.0103 | 0.0103 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.01 | 0.0127 | 0.0514 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0215 | 0.0326 | 0.4075 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0052 | 0.0045 | 0.0527 |
Schistosoma mansoni | cpg binding protein | 0.0098 | 0.0125 | 0.0506 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0117 | 0.0158 | 0.4123 |
Echinococcus multilocularis | dna polymerase kappa | 0.0117 | 0.0158 | 0.0158 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0304 | 0.0479 | 0.5633 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0052 | 0.0045 | 0.0045 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0052 | 0.0045 | 0.0527 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0078 | 0.0091 | 0.1107 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0036 | 0.0425 |
Onchocerca volvulus | 0.0095 | 0.0119 | 0.1952 | |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0316 | 0.0502 | 0.6252 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0124 | 0.0169 | 0.0696 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0117 | 0.0158 | 0.0158 |
Echinococcus granulosus | FTZ F1 alpha | 0.0052 | 0.0045 | 0.0183 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0018 | 0.048 |
Plasmodium falciparum | pyruvate kinase | 0.0103 | 0.0133 | 1 |
Brugia malayi | Inositol-1 | 0.0076 | 0.0087 | 0.1064 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0034 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.0475 | 0.5936 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Schistosoma mansoni | zinc finger protein | 0.0044 | 0.0031 | 0.0119 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0052 | 0.0045 | 0.0527 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0164 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0087 | 0.1088 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0164 | 0.0238 | 0.2974 |
Trypanosoma brucei | calpain-like protein, putative | 0.0059 | 0.0057 | 0.0629 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0036 | 0.0018 | 0.0167 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0674 |
Leishmania major | pyruvate kinase | 0.0103 | 0.0133 | 0.1561 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0199 | 0.0298 | 0.3724 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0036 | 0.0036 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.0475 | 0.0475 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0084 | 0.471 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0126 | 0.0172 | 0.0172 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0103 | 0.0133 | 0.2182 |
Onchocerca volvulus | Huntingtin homolog | 0.0378 | 0.0609 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.005 | 0.0042 | 0.0171 |
Loa Loa (eye worm) | calpain | 0.0059 | 0.0057 | 0.0716 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0052 | 0.0045 | 0.0173 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0076 | 0.0087 | 0.4955 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0117 | 0.0158 | 1 |
Trypanosoma brucei | antigen, putative | 0.0059 | 0.0057 | 0.0629 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0966 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0018 | 0.0226 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0011 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0334 | 0.0532 | 0.6632 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.009 | 0.011 | 0.1373 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0052 | 0.0045 | 0.0527 |
Brugia malayi | hypothetical protein | 0.049 | 0.0801 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.7232 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0103 | 0.1284 |
Trypanosoma brucei | unspecified product | 0.0081 | 0.0095 | 0.1074 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0011 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0027 | 0.0331 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.0475 | 0.1948 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0018 | 0.0558 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0084 | 0.471 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0036 | 0.0018 | 0.0214 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1855 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0214 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0036 | 0.0018 | 0.11 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.7232 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0079 | 0.0079 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0076 | 0.0087 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0196 | 0.245 |
Mycobacterium ulcerans | putative regulatory protein | 0.0074 | 0.0083 | 0.3016 |
Giardia lamblia | Pyruvate kinase | 0.0053 | 0.0046 | 0.2022 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0045 | 0.0045 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0087 | 0.0105 | 0.1238 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0036 | 0.0018 | 0.0167 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.007 | 0.0278 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0081 | 0.0095 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0133 | 0.1659 |
Echinococcus granulosus | pyruvate kinase | 0.0053 | 0.0046 | 0.0191 |
Onchocerca volvulus | 0.0139 | 0.0196 | 0.3222 | |
Giardia lamblia | Pyruvate kinase | 0.0103 | 0.0133 | 0.8207 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0018 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.0609 | 0.7604 |
Onchocerca volvulus | 0.0047 | 0.0036 | 0.0598 | |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0079 | 0.0989 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0103 | 0.0133 | 0.1634 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0076 | 0.0087 | 0.3244 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0079 | 0.0324 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0966 | 0.1622 | 0.1622 |
Schistosoma mansoni | pyruvate kinase | 0.0053 | 0.0046 | 0.0181 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0045 | 0.0045 |
Echinococcus granulosus | dna polymerase eta | 0.0168 | 0.0245 | 0.1008 |
Trypanosoma brucei | calpain-like protein, putative | 0.0059 | 0.0057 | 0.0629 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0117 | 0.0158 | 0.6553 |
Echinococcus granulosus | zinc finger transcription factor gli2 | 0.0316 | 0.0502 | 0.2064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0052 | 0.0045 | 0.0732 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0011 | 0.0037 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0091 | 0.0364 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0052 | 0.0045 | 0.0557 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0036 | 0.0455 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0233 | 0.0357 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0095 | 0.119 |
Loa Loa (eye worm) | inositol-1 | 0.0076 | 0.0087 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0048 | 0.0595 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0167 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0191 | 0.0285 | 0.1165 |
Echinococcus granulosus | calpain 7 C02 family | 0.0059 | 0.0057 | 0.0236 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.0094 | 0.1145 |
Loa Loa (eye worm) | pyruvate kinase | 0.0103 | 0.0133 | 0.1659 |
Echinococcus granulosus | intermediate filament protein | 0.0085 | 0.0103 | 0.0423 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0103 | 0.0133 | 0.1561 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0674 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0103 | 0.0133 | 0.1521 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0031 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0862 | 0.1443 | 0.1443 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0018 | 0.0483 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0052 | 0.0045 | 0.0045 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Echinococcus multilocularis | calpain | 0.0059 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0067 | 0.084 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0117 | 0.0158 | 0.4188 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0081 | 0.0095 | 0.1074 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0966 | 0.1622 | 0.6676 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.007 | 0.0278 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0126 | 0.0172 | 0.2025 |
Plasmodium vivax | calpain, putative | 0.0059 | 0.0057 | 0.4138 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0298 | 0.3724 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0052 | 0.0045 | 0.0527 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0087 | 0.1058 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0048 | 0.0196 |
Loa Loa (eye worm) | intermediate filament protein | 0.0085 | 0.0103 | 0.1284 |
Schistosoma mansoni | nuclear hormone receptor | 0.0052 | 0.0045 | 0.0173 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0117 | 0.0158 | 0.1972 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0117 | 0.0158 | 0.064 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0041 | 0.0026 | 0.0327 |
Leishmania major | pyroglutamyl-peptidase I (C15 family) | 0.0519 | 0.0851 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0304 | 0.0479 | 0.5633 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0052 | 0.0045 | 0.0557 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.0199 | 0.0808 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0018 | 0.1372 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.0203 | 0.239 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0103 | 0.0133 | 0.1561 |
Schistosoma mansoni | intermediate filament proteins | 0.0085 | 0.0103 | 0.0413 |
Echinococcus granulosus | lamin | 0.0085 | 0.0103 | 0.0423 |
Schistosoma mansoni | inositol monophosphatase | 0.0076 | 0.0087 | 0.035 |
Trypanosoma brucei | ISWI complex protein | 0.003 | 0.0008 | 0.0045 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0087 | 0.1027 |
Echinococcus granulosus | pyruvate kinase | 0.0103 | 0.0133 | 0.0547 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.0475 | 0.1956 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0298 | 0.3724 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0201 | 0.0819 |
Echinococcus granulosus | geminin | 0.017 | 0.0249 | 0.1026 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0142 | 0.0201 | 0.2514 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0248 | 0.0384 | 0.4776 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0029 | 0.0295 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0124 | 0.0169 | 0.0169 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0052 | 0.0045 | 0.0527 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0011 | 0.0291 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0212 |
Schistosoma mansoni | inositol monophosphatase | 0.0076 | 0.0087 | 0.035 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0674 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0018 | 0.0197 |
Schistosoma mansoni | lamin | 0.0085 | 0.0103 | 0.0413 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0084 | 0.471 |
Echinococcus multilocularis | calpain 5 | 0.0059 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0067 | 0.084 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0175 | 0.0258 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0018 | 0.048 |
Loa Loa (eye worm) | zinc finger protein | 0.0316 | 0.0502 | 0.6264 |
Onchocerca volvulus | 0.0036 | 0.0018 | 0.0299 | |
Brugia malayi | calpain 5 | 0.0059 | 0.0057 | 0.0688 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0085 | 0.0103 | 0.1284 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0029 | 0.0005 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0378 | 0.0609 | 0.7597 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0117 | 0.0158 | 0.064 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0018 | 0.048 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0018 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0052 | 0.0045 | 0.0527 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0078 | 0.0091 | 0.0374 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0117 | 0.0158 | 0.1816 |
Schistosoma mansoni | calpain (C02 family) | 0.0059 | 0.0057 | 0.0226 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0076 | 0.0087 | 0.036 |
Onchocerca volvulus | 0.0085 | 0.0103 | 0.1689 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.1433 | 0.243 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0018 | 0.0483 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1433 | 0.243 | 1 |
Echinococcus granulosus | calpain 5 | 0.0059 | 0.0057 | 0.0236 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0068 | 0.0074 | 0.1632 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0027 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0078 | 0.0091 | 0.1135 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0018 | 0.0197 |
Echinococcus multilocularis | pyruvate kinase | 0.0103 | 0.0133 | 0.0133 |
Schistosoma mansoni | thyroid hormone receptor | 0.0052 | 0.0045 | 0.0173 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0052 | 0.0045 | 0.0183 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0004 | 0.0006 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0053 | 0.0046 | 0.1668 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0214 |
Schistosoma mansoni | calpain C (C02 family) | 0.0059 | 0.0057 | 0.0226 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0048 | 0.0048 |
Schistosoma mansoni | zinc finger protein | 0.003 | 0.0008 | 0.0022 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0052 | 0.0045 | 0.0557 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0018 | 0.048 |
Brugia malayi | nuclear hormone receptor | 0.0052 | 0.0045 | 0.0527 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0674 |
Onchocerca volvulus | Huntingtin homolog | 0.0378 | 0.0609 | 1 |
Leishmania major | kinesin, putative | 0.0059 | 0.0057 | 0.0674 |
Brugia malayi | intermediate filament protein | 0.0085 | 0.0103 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Trypanosoma cruzi | pyroglutamyl-peptidase I, putative | 0.0519 | 0.0851 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0164 | 0.0238 | 0.2952 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0078 | 0.0091 | 0.0091 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0117 | 0.0158 | 0.1948 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0087 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0384 | 0.4792 |
Trypanosoma cruzi | ISWI complex protein | 0.003 | 0.0008 | 0.0093 |
Schistosoma mansoni | bromodomain containing protein | 0.0131 | 0.0182 | 0.0737 |
Echinococcus granulosus | dna polymerase kappa | 0.0117 | 0.0158 | 0.065 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Schistosoma mansoni | lamin | 0.0085 | 0.0103 | 0.0413 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0036 | 0.0036 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0036 | 0.014 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0046 | 0.0034 | 0.0429 |
Entamoeba histolytica | protein kinase, putative | 0.0059 | 0.0057 | 0.2808 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0036 | 0.0018 | 0.0167 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0052 | 0.0045 | 0.0173 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0048 | 0.0048 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.1101 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0103 | 0.0133 | 0.1521 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0052 | 0.0045 | 0.0183 |
Onchocerca volvulus | 0.01 | 0.0128 | 0.2099 | |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0076 | 0.0087 | 0.1027 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0103 | 0.0133 | 0.3524 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Plasmodium vivax | pyruvate kinase, putative | 0.0103 | 0.0133 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0052 | 0.0045 | 0.0183 |
Echinococcus multilocularis | cpg binding protein | 0.0098 | 0.0125 | 0.0125 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0078 | 0.0091 | 0.0374 |
Echinococcus granulosus | pyruvate kinase | 0.0053 | 0.0046 | 0.0191 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0036 | 0.015 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0076 | 0.0087 | 0.2317 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0076 | 0.0087 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0067 | 0.084 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0076 | 0.0087 | 0.2317 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0236 | 0.0363 | 0.4536 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0084 | 0.0084 |
Brugia malayi | ecdysteroid receptor | 0.0052 | 0.0045 | 0.0527 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0066 | 0.007 | 0.007 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0029 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0196 | 0.245 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0034 | 0.0014 | 0.0047 |
Schistosoma mansoni | coup transcription factor | 0.0052 | 0.0045 | 0.0173 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1816 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0629 |
Echinococcus granulosus | calpain | 0.0059 | 0.0057 | 0.0236 |
Onchocerca volvulus | 0.0032 | 0.0011 | 0.0188 | |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0018 | 0.048 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0052 | 0.0045 | 0.0183 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0674 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0018 | 0.048 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0018 | 0.1372 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0304 | 0.0479 | 0.5612 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0052 | 0.0045 | 0.0527 |
Mycobacterium ulcerans | pyruvate kinase | 0.0103 | 0.0133 | 0.5378 |
Trypanosoma brucei | unspecified product | 0.0081 | 0.0095 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.0059 | 0.0057 | 0.0226 |
Trypanosoma cruzi | kinesin, putative | 0.0059 | 0.0057 | 0.0674 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0076 | 0.0087 | 0.3277 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0004 | 0.002 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0036 | 0.0018 | 0.11 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0029 | 0.0341 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0035 | 0.0016 | 0.02 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0117 | 0.0158 | 0.1855 |
Chlamydia trachomatis | pyruvate kinase | 0.0103 | 0.0133 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.01 | 0.0128 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0031 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.049 | 0.0801 | 0.0801 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0018 | 0.0228 |
Onchocerca volvulus | 0.0036 | 0.0018 | 0.0299 | |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0052 | 0.0045 | 0.0173 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0029 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0067 | 0.0267 |
Loa Loa (eye worm) | calpain 5 | 0.0059 | 0.0057 | 0.0716 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0047 | 0.0036 | 0.0598 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0011 | 0.0037 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0048 | 0.0566 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0201 | 0.0819 |
Echinococcus multilocularis | hypothetical protein | 0.0059 | 0.0057 | 0.0057 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0004 | 0.0017 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0078 | 0.0091 | 0.0091 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0006 | 0.0025 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0059 | 0.0057 | 0.0674 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0084 | 0.1021 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0052 | 0.0045 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0004 | 0.0051 |
Echinococcus granulosus | pyruvate kinase | 0.0053 | 0.0046 | 0.0191 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0067 | 0.0277 |
Leishmania major | DNA damage repair protein, putative | 0.0036 | 0.0018 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0026 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0002 | 0.0031 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0059 | 0.0057 | 0.0674 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0103 | 0.0133 | 0.5066 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0167 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0139 | 0.0196 | 0.245 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0066 | 0.007 | 0.0288 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0018 | 0.0212 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0052 | 0.0045 | 0.0045 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0117 | 0.0158 | 0.4123 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0126 | 0.0172 | 0.6621 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0144 | 0.0203 | 0.2353 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0084 | 0.0336 |
Trypanosoma brucei | kinesin, putative | 0.0059 | 0.0057 | 0.0629 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0018 | 0.0483 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0018 | 0.0214 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0018 | 0.0065 |
Onchocerca volvulus | 0.0244 | 0.0377 | 0.6193 | |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0103 | 0.0133 | 0.2182 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0041 | 0.0027 | 0.0027 |
Echinococcus multilocularis | zinc finger transcription factor gli2 | 0.0316 | 0.0502 | 0.0502 |
Trichomonas vaginalis | set domain proteins, putative | 0.0244 | 0.0377 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.0201 | 0.0828 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0008 | 0.0022 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0067 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0198 | 0.2476 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0557 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0052 | 0.0045 | 0.0045 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1433 | 0.243 | 0.243 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0052 | 0.0045 | 0.0173 |
Echinococcus granulosus | lamin dm0 | 0.0085 | 0.0103 | 0.0423 |
Echinococcus granulosus | pyruvate kinase | 0.0103 | 0.0133 | 0.0547 |
Onchocerca volvulus | 0.0074 | 0.0083 | 0.1355 | |
Mycobacterium ulcerans | DNA polymerase IV | 0.0117 | 0.0158 | 0.6553 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0036 | 0.0018 | 0.0214 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0059 | 0.0057 | 0.0226 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0052 | 0.0045 | 0.0045 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Affected Entity | Phenotypic quality | Occurs in | Occurs at | Evidence | Observed in | Targets |
---|---|---|---|---|---|---|
catalytic activity (GO:0003824) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from structural similarity (ECO:0000027) | Leishmania major | 23720 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 26305-03-3. chemical inhibition with known cysteine peptidase inhibitors leads to reduced enzyme activity in vitro; | References: | 17028008 | |
catalytic activity (GO:0003824) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania major | 23720 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 26305-03-3. chemical inhibition with known cysteine peptidase inhibitors leads to reduced enzyme activity in vitro; | References: | 17028008 |
7 literature references were collected for this gene.