Detailed information for compound 664803

Basic information

Technical information
  • TDR Targets ID: 664803
  • Name: STK223919
  • MW: 368.34 | Formula: C19H16N2O6
  • H donors: 3 H acceptors: 6 LogP: 2.35 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN1C(=O)c2c(C1=O)cc(cc2)C(=O)Nc1ccc(cc1C(=O)O)O
  • InChi: 1S/C19H16N2O6/c1-2-7-21-17(24)12-5-3-10(8-13(12)18(21)25)16(23)20-15-6-4-11(22)9-14(15)19(26)27/h3-6,8-9,22H,2,7H2,1H3,(H,20,23)(H,26,27)
  • InChiKey: FUTGISZXERMCMC-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major acetoin dehydrogenase e3 component-like protein 0.008 0.0063 0.0298
Trichomonas vaginalis sensor histidine kinase, putative 0.0021 0.0009 0.0039
Plasmodium vivax heat shock protein 90, putative 0.0095 0.0077 0.0365
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0091 0.0432
Echinococcus granulosus tar DNA binding protein 0.0067 0.0051 0.0244
Trypanosoma brucei DNA topoisomerase ii 0.0021 0.0009 0.0039
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0111 0.0091 0.0438
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0034 0.0162
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.0712 0.3407
Mycobacterium tuberculosis Probable oxidoreductase 0.0585 0.0525 0.0518
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0005 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0071 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0009 0.0044
Leishmania major hypothetical protein, conserved 0.0021 0.0009 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0009 0.0044
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0009 0.0044
Brugia malayi hypothetical protein 0.0058 0.0042 0.0202
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0664 0.0597 0.2861
Brugia malayi glutaminase DH11.1 0.033 0.0292 0.1397
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0008 0.0001
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0021 0.0009 0.0043
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0025 0.0121
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0017 0.0079
Brugia malayi Thioredoxin reductase 0.0231 0.0201 0.0961
Trichomonas vaginalis receptor histidine kinase, putative 0.0021 0.0009 0.0039
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.002 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0021 0.0009 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0104 0.0495
Trypanosoma cruzi trypanothione reductase, putative 0.008 0.0063 0.0298
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0007 0.0031
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0664 0.0597 0.2859
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0017 0.0079
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0009 0.0041
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0021 0.0009 0.0001
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0021 0.0009 0.0043
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0021 0.0009 0.0043
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0585 0.0525 0.0518
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0051 0.0244
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0009 0.0043
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0009 0.0041
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0033 0.002 0.0094
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.002 0.0095
Giardia lamblia DINP protein human, muc B family 0.002 0.0008 0.0034
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0021 0.0009 0.0009
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0009 0.0043
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0134 0.0113 0.0707
Toxoplasma gondii exonuclease III APE 0.002 0.0008 0.0037
Echinococcus granulosus cysteine protease 0.0017 0.0005 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0022
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0016 0.0072
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0044
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Mycobacterium tuberculosis Probable two component sensor kinase 0.0021 0.0009 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.008 0.0063 0.0298
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0021 0.0009 0.0041
Brugia malayi nuclear receptor NHR-88 0.0022 0.0009 0.0044
Giardia lamblia Thioredoxin reductase 0.0021 0.0009 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0083 0.0066 0.0313
Giardia lamblia Heat shock protein HSP 90-alpha 0.0143 0.0121 0.0575
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.2293 0.2089 1
Trypanosoma brucei developmentally regulated phosphoprotein 0.0021 0.0009 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0025 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0009 0.0041
Trypanosoma brucei trypanothione reductase 0.0231 0.0201 0.0959
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0008 0.0034
Onchocerca volvulus 0.0033 0.002 0.0246
Echinococcus multilocularis cathepsin L 0.0017 0.0005 0.0024
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0008 0.0034
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0025 0.0121
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0008 0.0034
Echinococcus granulosus snurportin 1 0.0303 0.0267 0.1277
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0008 0.0037
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0009 0.0003
Echinococcus granulosus lamin dm0 0.0026 0.0014 0.0065
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0009 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0143 0.0121 0.0575
Loa Loa (eye worm) hypothetical protein 0.0111 0.0091 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Onchocerca volvulus 0.0021 0.0009 0.0077
Leishmania major cathepsin L-like protease 0.0033 0.002 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0033 0.002 0.0092
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0009 0.0044
Leishmania major dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.008 0.0063 0.0298
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0021 0.0009 0.0001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0008 0.0037
Schistosoma mansoni ran 0.0021 0.0009 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0526 0.0471 0.0464
Leishmania major dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Plasmodium vivax multidomain scavenger receptor, putative 0.0058 0.0042 0.02
Plasmodium vivax ferrodoxin reductase, putative 0.0021 0.0009 0.0041
Echinococcus multilocularis lamin 0.0026 0.0014 0.0065
Trypanosoma brucei Heat shock protein 83, putative 0.0143 0.0121 0.0575
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0008 0.0001
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0016 0.0074
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0009 0.0039
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0711 0.064 0.0633
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0009 0.0002
Schistosoma mansoni hypothetical protein 0.0337 0.0298 0.1427
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0009 0.0041
Echinococcus granulosus microtubule associated protein 2 0.2019 0.1838 0.8801
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0155 0.0744
Giardia lamblia Grp94/Hsp90 0.0134 0.0113 0.0537
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.008 0.0063 0.0298
Loa Loa (eye worm) programmed cell death 8 0.0021 0.0009 0.0043
Echinococcus multilocularis ng dimethylarginine dimethylaminohydrolase 0.0176 0.0151 0.0722
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0091 0.0432
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0222 0.0193 0.0924
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0009 0.0044
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.002 0.0092
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0009 0.0044
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.0154 0.0147
Brugia malayi Cathepsin L-like precursor 0.0033 0.002 0.0094
Onchocerca volvulus 0.0033 0.002 0.0246
Treponema pallidum heat shock protein 90 0.0134 0.0113 0.0537
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0021 0.0009 0.0041
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Leishmania major hypothetical protein, conserved 0.0021 0.0009 0.0039
Toxoplasma gondii Hsp90 domain-containing protein 0.0542 0.0486 0.2326
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0526 0.0471 0.0464
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0076
Echinococcus multilocularis endoplasmin 0.0134 0.0113 0.0539
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0017 0.0079
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0012 0 0.0002
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0021 0.0009 0.0039
Leishmania major hypothetical protein, unknown function 0.0176 0.0151 0.072
Loa Loa (eye worm) hypothetical protein 0.0111 0.0091 0.0438
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0091 0.0436
Plasmodium falciparum glutathione reductase 0.008 0.0063 0.0298
Leishmania major DNA topoisomerase ii 0.0021 0.0009 0.0039
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.008 0.0063 0.0298
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0021 0.0009 0.0001
Echinococcus multilocularis heat shock protein 0.0143 0.0121 0.0577
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0091 0.0084
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0021 0.0009 0.0001
Schistosoma mansoni importin beta-1 0.0028 0.0016 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0009 0.0044
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0037 0.0178
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0022
Echinococcus granulosus heat shock protein 90 0.0143 0.0121 0.0577
Leishmania major hypothetical protein, conserved 0.0021 0.0009 0.0041
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0009 0.0044
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Mycobacterium tuberculosis Possible two component sensor kinase 0.0021 0.0009 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0004 0.0017
Mycobacterium tuberculosis Conserved protein 0.0111 0.0091 0.0084
Schistosoma mansoni glutamate synthase 0.0021 0.0009 0.0043
Trypanosoma cruzi cysteine protease, putative 0.0017 0.0005 0.0022
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0059 0.0043 0.0207
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0009 0.0039
Leishmania major trypanothione reductase 0.0231 0.0201 0.0959
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0016 0.0008
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0664 0.0597 0.2859
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0021 0.0009 0.0009
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Schistosoma mansoni microtubule-associated protein tau 0.2019 0.1838 0.8801
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Schistosoma mansoni glutamate synthase 0.0021 0.0009 0.0043
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0009 0.0044
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0021 0.0009 0.0003
Trypanosoma cruzi heat shock protein 90, putative 0.006 0.0044 0.0211
Brugia malayi Cathepsin L-like precursor 0.0033 0.002 0.0094
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Loa Loa (eye worm) glutathione reductase 0.0231 0.0201 0.0961
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0021 0.0009 0.0001
Entamoeba histolytica heat shock protein 90, putative 0.0143 0.0121 0.0575
Leishmania major cathepsin L-like protease 0.0033 0.002 0.0092
Plasmodium vivax unspecified product 0.0017 0.0005 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.0154 0.0147
Trypanosoma cruzi DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0007 0.0031
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.2293 0.2089 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0049 0.0034 0.0163
Schistosoma mansoni rab6-interacting 0.0058 0.0042 0.0202
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0007 0.0033
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0008 0.0036
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0016 0.0072
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0202
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0071 0.0341
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0009 0.0044
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0007 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0091 0.0432
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0009 0.0041
Toxoplasma gondii thioredoxin reductase 0.0231 0.0201 0.0959
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0091 0.0432
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0009 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Brugia malayi beta-lactamase 0.0111 0.0091 0.0438
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0121
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0089 0.0071 0.0341
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0016 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.0207 0.0989
Echinococcus granulosus cathepsin L cysteine proteinase 0.0033 0.002 0.0094
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0009 0.0044
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0005 0.0024
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0104 0.0495
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0021 0.0009 0.0043
Plasmodium vivax heat shock protein 86, putative 0.0143 0.0121 0.0575
Brugia malayi NG,NG-dimethylarginine dimethylaminohydrolase 1, putative 0.0176 0.0151 0.0722
Trypanosoma brucei heat shock protein 84, putative 0.0095 0.0077 0.0365
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0021 0.0009 0.0069
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0025 0.0121
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0021 0.0009 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Leishmania major developmentally regulated phosphoprotein-like protein 0.0021 0.0009 0.0039
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0009 0.0041
Schistosoma mansoni endoplasmin 0.0143 0.0121 0.0577
Schistosoma mansoni Microrchidia 2a 0.0012 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0076
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0017 0.0079
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0664 0.0597 0.2859
Leishmania major DNA polymerase eta, putative 0.002 0.0008 0.0034
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0007 0.0033
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0021 0.0009 0.0001
Loa Loa (eye worm) RNA binding protein 0.0067 0.0051 0.0244
Echinococcus granulosus RUN 0.0058 0.0042 0.0202
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0009 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0016 0.0073
Leishmania major cathepsin L-like protease 0.0033 0.002 0.0092
Giardia lamblia GTOR 0.0019 0.0007 0.0031
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0021 0.0009 0.0043
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0585 0.0525 0.3507
Giardia lamblia Glutamate synthase 0.0021 0.0009 0.0041
Brugia malayi nuclear hormone receptor 0.0022 0.0009 0.0044
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.2293 0.2089 1
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0049 0.0034 0.0161
Echinococcus granulosus mixed lineage leukemia protein mll 0.0012 0 0.0002
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0009 0.0039
Mycobacterium ulcerans flavoprotein disulfide reductase 0.008 0.0063 0.0055
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0008 0.0037
Leishmania major cathepsin L-like protease 0.0125 0.0104 0.0495
Schistosoma mansoni coup transcription factor 0.0022 0.0009 0.0044
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0017
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0095 0.0077 0.0367
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0065
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0071 0.0341
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0091 0.0438
Giardia lamblia Heat shock protein HSP 90-alpha 0.0122 0.0102 0.0485
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0009 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0091 0.0438
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0004
Schistosoma mansoni intermediate filament proteins 0.0026 0.0014 0.0065
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.008 0.0063 0.03
Mycobacterium ulcerans beta-lactamase 0.0111 0.0091 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0002 0.0007
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0664 0.0597 0.2859
Plasmodium vivax DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0009 0.0041
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0013 0.0064
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0021 0.0009 0.0041
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0021 0.0009 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0043
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.2293 0.2089 1
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0021 0.0009 0.0041
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0021 0.0009 0.0001
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.2293 0.2089 1
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0122 0.0102 0.0487
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0021 0.0009 0.0039
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0021 0.0009 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0155 0.0744
Schistosoma mansoni heat shock protein 0.0143 0.0121 0.0577
Loa Loa (eye worm) hypothetical protein 0.0033 0.002 0.0094
Onchocerca volvulus Cathepsin L homolog 0.0033 0.002 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Plasmodium vivax SET domain protein, putative 0.0089 0.0071 0.0339
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0025 0.0118
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0585 0.0525 0.0518
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0202
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0007 0.0031
Trypanosoma cruzi DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.2293 0.2089 1
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0095 0.0077 0.0367
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0007 0.0031
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0021 0.0009 0.0041
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0007 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0051 0.0244
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0042 0.0202
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0009 0.0044
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0095 0.0077 0.0365
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0021 0.0009 0.0041
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.008 0.0063 0.0298
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0008 0.0037
Toxoplasma gondii NADPH-glutathione reductase 0.008 0.0063 0.0298
Brugia malayi Importin beta-1 subunit 0.0028 0.0016 0.0074
Toxoplasma gondii heat shock protein 75, putative 0.0095 0.0077 0.0365
Trichomonas vaginalis DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0044 0.0037
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0046
Schistosoma mansoni hypothetical protein 0.0012 0 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0017 0.0079
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0041
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0091 0.0559
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0134 0.0113 0.0112
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0017 0.0016
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0021 0.0009 0.0041
Plasmodium vivax glutathione reductase, putative 0.0231 0.0201 0.0959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0004 0.0017
Echinococcus multilocularis cysteine protease 0.0033 0.002 0.0094
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0042 0.0202
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0025 0.0118
Trypanosoma cruzi heat shock protein, putative 0.0095 0.0077 0.0365
Entamoeba histolytica disulphide oxidoreductase, putative 0.0021 0.0009 0.0041
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0011 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0176 0.0151 0.0722
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0016 0.0008
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0114 0.0094 0.0448
Loa Loa (eye worm) hypothetical protein 0.0033 0.002 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0091 0.0435
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0021 0.0009 0.0009
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0049 0.0034 0.0163
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0017
Schistosoma mansoni cpg binding protein 0.0037 0.0023 0.0111
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0021 0.0009 0.0039
Schistosoma mansoni microrchidia 2a 0.0012 0 0.0002
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0009 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0016 0.0008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0008 0.0036
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0025 0.0118
Entamoeba histolytica cysteine proteinase 2 0.0017 0.0005 0.0022
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0664 0.0597 0.2861
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0009 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0004 0.0017
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.0267 0.1277
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0017 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0021 0.0009 0.0043
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0009 0.0042
Onchocerca volvulus Cathepsin L homolog 0.0033 0.002 0.0246
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0014 0.0065
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0526 0.0471 0.0464
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0007 0.0033
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0002 0.0012
Schistosoma mansoni disulfide oxidoreductase 0.0021 0.0009 0.0043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0004
Echinococcus multilocularis dna polymerase eta 0.002 0.0008 0.0036
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0044 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0009 0.0044
Plasmodium falciparum thioredoxin reductase 0.008 0.0063 0.0298
Echinococcus granulosus dna polymerase kappa 0.002 0.0008 0.0036
Brugia malayi CXXC zinc finger family protein 0.0035 0.0021 0.0102
Brugia malayi kinase, mitochondrial precursor 0.0021 0.0009 0.0041
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0095 0.0077 0.1154
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0091 0.0083
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0155 0.0744
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0005 0.0022
Onchocerca volvulus 0.0058 0.0042 0.0607
Loa Loa (eye worm) thioredoxin reductase 0.0231 0.0201 0.0961
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0013 0.0062
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0091 0.0432
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0009 0.0044
Onchocerca volvulus Cathepsin F homolog 0.0033 0.002 0.0246
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0009 0.0041
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0021 0.0009 0.0003
Leishmania major importin beta-1 subunit, putative 0.0023 0.0011 0.0049
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0046
Loa Loa (eye worm) endoplasmin 0.0143 0.0121 0.0577
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.008 0.0063 0.0298
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0007 0.0033
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0009 0.0001
Leishmania major hypothetical protein, conserved 0.0111 0.0091 0.0436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Trichomonas vaginalis glutathione reductase, putative 0.008 0.0063 0.0298
Plasmodium falciparum endoplasmin, putative 0.0104 0.0085 0.0403
Toxoplasma gondii DNA topoisomerase 2, putative 0.0021 0.0009 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0041
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0009 0.0044
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.008 0.0063 0.0055
Trypanosoma brucei unspecified product 0.0014 0.0002 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.002 0.0094
Brugia malayi steroid hormone receptor 0.0022 0.0009 0.0044
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0101 0.0482
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0004 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0051 0.0244
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0017 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0016 0.0008
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Mycobacterium ulcerans glutaminase 0.033 0.0292 0.0284
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0021 0.0009 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0009 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0013 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Echinococcus multilocularis dna polymerase kappa 0.002 0.0008 0.0036
Brugia malayi DNA mismatch repair protein MutL containing protein 0.0012 0 0.0002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0008 0.0036
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.001 0.0044
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0008 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0051 0.0244
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0009 0.0042
Plasmodium falciparum heat shock protein 90 0.0143 0.0121 0.0575
Mycobacterium ulcerans lipase LipD 0.0111 0.0091 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0021 0.0009 0.0001
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0007 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0025 0.0118
Brugia malayi beta-lactamase family protein 0.0111 0.0091 0.0438
Schistosoma mansoni pyruvate dehydrogenase 0.0021 0.0009 0.0041
Echinococcus multilocularis thioredoxin glutathione reductase 0.0234 0.0203 0.0974
Schistosoma mansoni lamin 0.0026 0.0014 0.0065
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0009 0.0044
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0091 0.0436
Brugia malayi RNA, U transporter 1 0.0081 0.0063 0.0304
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0009 0.0041
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0039
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.002 0.0094
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0021 0.0009 0.0039
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0001 0.0006
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0007 0.0031
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0101 0.0482
Brugia malayi Probable DNA topoisomerase II 0.0021 0.0009 0.0041
Plasmodium vivax endoplasmin, putative 0.0143 0.0121 0.0575
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.008 0.0063 0.0062
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.008 0.0063 0.0055
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0007 0.0031
Echinococcus granulosus ng dimethylarginine dimethylaminohydrolase 0.0176 0.0151 0.0722
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0009 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0009 0.0044
Mycobacterium ulcerans glutamate synthase subunit beta 0.0021 0.0009 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0002 0.0007
Mycobacterium ulcerans ferredoxin reductase 0.0021 0.0009 0.0001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0091 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0071 0.0341
Echinococcus granulosus cathepsin L cysteine protease 0.0017 0.0005 0.0024
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0014 0.0065
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0005 0.0024
Echinococcus multilocularis cpg binding protein 0.0037 0.0023 0.0111
Plasmodium falciparum glutathione reductase 0.0231 0.0201 0.0959
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.008 0.0063 0.0062
Trichomonas vaginalis glutaminase, putative 0.033 0.0292 0.1395
Mycobacterium leprae conserved hypothetical protein 0.0111 0.0091 0.0563
Trypanosoma cruzi heat shock protein 85, putative 0.0143 0.0121 0.0575
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0048
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0091 0.0436
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0021 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0016 0.0076
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0058 0.0042 0.0202
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0021 0.0009 0.0001
Onchocerca volvulus 0.0033 0.002 0.0246
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0036
Echinococcus granulosus GPCR family 2 0.0015 0.0004 0.0017
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0007 0.0031
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0002 0.0011
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0008 0.0037
Chlamydia trachomatis DNA gyrase subunit B 0.0021 0.0009 0.0008
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0007 0.0031
Schistosoma mansoni ngng-dimethylarginine dimethylaminohydrolase 0.0176 0.0151 0.0722
Schistosoma mansoni survival motor neuron protein 0.0048 0.0034 0.0162
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0091 0.0084
Entamoeba histolytica DNA topoisomerase II, putative 0.0021 0.0009 0.0039
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0 0.0002
Schistosoma mansoni glutaminase 0.033 0.0292 0.1397
Entamoeba histolytica thioredoxin reductase, putative 0.0021 0.0009 0.0041
Echinococcus multilocularis RUN 0.0058 0.0042 0.0202
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0009 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0009 0.0044
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0044 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.002 0.0092
Loa Loa (eye worm) glutaminase 2 0.033 0.0292 0.1397
Echinococcus multilocularis GPCR, family 2 0.0015 0.0004 0.0017
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0017
Trypanosoma cruzi heat shock protein 85, putative 0.0143 0.0121 0.0575
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0025 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Brugia malayi Hsp90 protein 0.0095 0.0077 0.0367
Echinococcus granulosus heat shock protein 90 0.0122 0.0102 0.0487
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0017 0.0079
Schistosoma mansoni lipoxygenase 0.0119 0.0098 0.047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Toxoplasma gondii selenide, water dikinase 0.0021 0.0009 0.0041
Brugia malayi RNA binding protein 0.0067 0.0051 0.0244
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0008 0.0034
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0014 0.0065
Echinococcus granulosus heat shock protein 0.0143 0.0121 0.0577
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0013 0.0062
Echinococcus granulosus thioredoxin glutathione reductase 0.0234 0.0203 0.0974
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0017 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Echinococcus granulosus MORC family CW type zinc finger protein 2B 0.0012 0 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0005 0.0024
Schistosoma mansoni loxhd1 0.0058 0.0042 0.0202
Plasmodium vivax vivapain-3 0.0017 0.0005 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0181 0.0155 0.0744
Onchocerca volvulus 0.0033 0.002 0.0246
Brugia malayi Doublecortin family protein 0.0058 0.0042 0.0202
Leishmania major cathepsin L-like protease 0.0125 0.0104 0.0495
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0021 0.0009 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trypanosoma cruzi heat shock protein 90, putative 0.0143 0.0121 0.0575
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.008 0.0063 0.0298
Echinococcus granulosus geminin 0.0337 0.0298 0.1427
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0009 0.0044
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0021 0.0009 0.0039
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0091 0.0436
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0021 0.0009 0.0041
Plasmodium vivax vivapain-2 0.0033 0.002 0.0092
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Onchocerca volvulus 0.0048 0.0034 0.0473
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0025 0.0121
Echinococcus granulosus cathepsin l1 0.0033 0.002 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0016 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0025 0.0118
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.008 0.0063 0.0055
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0021 0.0009 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.008 0.0063 0.0298
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0009 0.0041
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0021 0.0009 0.0001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0008 0.0039
Onchocerca volvulus 0.0702 0.0632 1
Brugia malayi beta-lactamase family protein 0.0111 0.0091 0.0438
Entamoeba histolytica cysteine proteinase 1, putative 0.0017 0.0005 0.0022
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0009 0.0041
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0021 0.0009 0.0001
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0021 0.0009 0.0001
Echinococcus multilocularis DNA mismatch repair protein Mlh1 0.0012 0 0.0002
Schistosoma mansoni heat shock protein 0.0095 0.0077 0.0367
Plasmodium falciparum DNA topoisomerase 2 0.0021 0.0009 0.0039
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0005 0.0022
Echinococcus multilocularis heat shock protein 90 0.0122 0.0102 0.0487
Schistosoma mansoni hypothetical protein 0.0337 0.0298 0.1427
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0021 0.0009 0.0041
Mycobacterium ulcerans putative regultory protein 0.0021 0.0009 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0005 0.0024
Echinococcus granulosus cathepsin l cysteine peptidase 0.0033 0.002 0.0094
Leishmania major DNA polymerase kappa, putative 0.002 0.0008 0.0034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0002 0.0011
Trichomonas vaginalis apoptosis inducing factor, putative 0.0021 0.0009 0.0041
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0025 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0009 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Onchocerca volvulus 0.0111 0.0091 0.1389
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.001 0.0046
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0009 0.0044
Schistosoma mansoni ngng-dimethylarginine dimethylaminohydrolase 0.0176 0.0151 0.0722
Schistosoma mansoni cpg binding protein 0.0035 0.0021 0.0102
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.002 0.0094
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0113 0.0537
Plasmodium falciparum cysteine proteinase falcipain 3 0.0033 0.002 0.0092
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0009 0.0041
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0091 0.0432
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0009 0.0044
Schistosoma mansoni DNA topoisomerase II 0.0021 0.0009 0.0041
Loa Loa (eye worm) TOPoisomerase family member 0.0021 0.0009 0.0041
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0034 0.0162
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0076
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0051 0.0244
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.2293 0.2089 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0044 0.0211
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0091 0.0436
Plasmodium vivax DNA gyrase subunit B, putative 0.0021 0.0009 0.0039
Echinococcus granulosus DNA mismatch repair protein Mlh1 0.0012 0 0.0002
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.2293 0.2089 1
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 1.0936 1 1
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.2293 0.2089 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Trichomonas vaginalis heat shock protein, putative 0.0122 0.0102 0.0485
Schistosoma mansoni endoplasmin 0.0143 0.0121 0.0577
Mycobacterium ulcerans heat shock protein 90 0.0134 0.0113 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0009 0.0044
Trypanosoma brucei unspecified product 0.002 0.0008 0.0034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0002 0.0012
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0016 0.0073
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0021 0.0009 0.0008
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0017 0.0016
Trypanosoma cruzi heat shock protein 90, putative 0.0122 0.0102 0.0485
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0016 0.0072
Giardia lamblia NADH oxidase lateral transfer candidate 0.008 0.0063 0.0298
Onchocerca volvulus 0.0033 0.002 0.0246
Trypanosoma brucei heat shock protein 90, putative 0.0143 0.0121 0.0575
Echinococcus granulosus histone lysine methyltransferase setb 0.0089 0.0071 0.0341
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0021 0.0009 0.0008
Brugia malayi cathepsin L-like precursor 0.0022 0.001 0.0046
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0005 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Schistosoma mansoni hypothetical protein 0.0494 0.0442 0.2115
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.001 0.0046
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0526 0.0471 0.3142
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0021 0.0009 0.0041
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0021 0.0009 0.0001
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0007 0.0031
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.002 0.0094
Mycobacterium ulcerans NADH dehydrogenase 0.0021 0.0009 0.0001
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0021 0.0009 0.0001
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0091 0.0432
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.002 0.0094
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0091 0.0084
Schistosoma mansoni hypothetical protein 0.0033 0.002 0.0095
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0007 0.0031
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0664 0.0597 0.2859
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0044
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0039
Mycobacterium tuberculosis Probable dehydrogenase 0.0526 0.0471 0.0464
Trypanosoma cruzi heat shock protein 85, putative 0.0143 0.0121 0.0575
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.002 0.0092
Loa Loa (eye worm) beta-lactamase 0.0111 0.0091 0.0438
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0016 0.0073
Onchocerca volvulus 0.0033 0.002 0.0246
Loa Loa (eye worm) hypothetical protein 0.0111 0.0091 0.0438
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0155 0.0744
Schistosoma mansoni DNA mismatch repair protein MLH1 0.0012 0 0.0002
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0021 0.0009 0.0043
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0021 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0017
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0011 0.0049
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0091 0.0435
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.008 0.0063 0.0298
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0009 0.0041
Echinococcus granulosus cathepsin l1 0.0022 0.001 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0442 0.2115
Loa Loa (eye worm) hypothetical protein 0.0237 0.0207 0.0989
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0017 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0009 0.0044
Mycobacterium leprae Probable lipase LipE 0.0111 0.0091 0.0563
Plasmodium falciparum ferrodoxin reductase-like protein 0.0021 0.0009 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0043
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0009 0.0042
Schistosoma mansoni ap endonuclease 0.002 0.0008 0.0039
Chlamydia trachomatis DNA gyrase subunit B 0.0021 0.0009 0.0008
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0021 0.0009 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0181 0.0155 0.0744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0009 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Onchocerca volvulus 0.0033 0.002 0.0246
Plasmodium vivax vivapain-2 0.0033 0.002 0.0092
Echinococcus granulosus cathepsin L 0.0017 0.0005 0.0024
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0091 0.0435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0009 0.0044
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0016 0.0008
Brugia malayi glutathione reductase 0.0231 0.0201 0.0961
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0017 0.0005 0.0022
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0013 0.0064
Echinococcus multilocularis expressed protein 0.0049 0.0034 0.0163
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0008 0.0008
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0021 0.0009 0.0001
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0021 0.0009 0.0001
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0021 0.0009 0.0001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.008 0.0063 0.03
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0005 0.0024
Mycobacterium ulcerans monoxygenase 0.0021 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0074
Onchocerca volvulus 0.0176 0.0151 0.2333
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0044 0.0037
Plasmodium falciparum cysteine proteinase falcipain 1 0.0017 0.0005 0.0022
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0664 0.0597 0.2861
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0007 0.0031
Brugia malayi heat shock protein 90 0.0143 0.0121 0.0577
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0091 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0155 0.0744
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.008 0.0063 0.0298
Trypanosoma cruzi Heat shock protein 83, putative 0.0143 0.0121 0.0575
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0162
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0025 0.0121
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0091 0.0083
Schistosoma mansoni DNA mismatch repair protein PMS2 0.0012 0 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0008 0.0039
Plasmodium vivax importin-beta 2, putative 0.0028 0.0016 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0009 0.0044
Schistosoma mansoni ran 0.0021 0.0009 0.0042
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0044 0.0037
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0009 0.0041
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.001 0.0046
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0155 0.0744
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Toxoplasma gondii cathepsin CPL 0.0033 0.002 0.0092
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0009 0.0039
Schistosoma mansoni lamin 0.0026 0.0014 0.0065
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0017 0.0079
Leishmania major cathepsin L-like protease 0.0125 0.0104 0.0495
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0009 0.0044
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0042
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0091 0.0084
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0008 0.0034
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.2293 0.2089 1
Loa Loa (eye worm) histone methyltransferase 0.0014 0.0002 0.0011
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0008 0.0034
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0021 0.0009 0.0001
Trypanosoma brucei NADH dehydrogenase 0.0021 0.0009 0.0041
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0016 0.0049
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0021 0.0009 0.0001
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.2293 0.2089 1
Brugia malayi 6-phosphofructokinase 0.0111 0.0091 0.0435
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0222 0.0193 0.0924
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.002 0.0094
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0044
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0017 0.0079
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0021 0.0009 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0009 0.0044
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0013 0.0064
Plasmodium vivax heat shock protein, putative 0.0542 0.0486 0.2326
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0001 0.0006
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.0207 0.0989
Trichomonas vaginalis esterase, putative 0.0111 0.0091 0.0436
Trypanosoma cruzi cruzipain precursor, putative 0.0125 0.0104 0.0495
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0091 0.0436
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0051 0.0244
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0017 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0008 0.0034
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0021 0.0009 0.0008
Schistosoma mansoni heat shock protein 0.0143 0.0121 0.0577
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Echinococcus multilocularis microtubule associated protein 2 0.2019 0.1838 0.8801
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0044 0.0211
Leishmania major hypothetical protein, unknown function 0.0176 0.0151 0.072
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0009 0.0041
Trypanosoma brucei unspecified product 0.0014 0.0002 0.0007
Schistosoma mansoni hypothetical protein 0.0303 0.0267 0.1277
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0016 0.0008
Onchocerca volvulus 0.0111 0.0091 0.1389
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.2293 0.2089 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.018 0.0154 0.0738
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0009 0.0041
Echinococcus granulosus intermediate filament protein 0.0026 0.0014 0.0065
Schistosoma mansoni DNA polymerase eta 0.002 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0 0.0002
Brugia malayi ecdysteroid receptor 0.0022 0.0009 0.0044
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0009 0.0044
Brugia malayi TAR-binding protein 0.0067 0.0051 0.0244
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0051 0.0244
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0009 0.0039
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.002 0.0094
Treponema pallidum oxidoreductase 0.0021 0.0009 0.0041
Trypanosoma brucei heat shock protein 90, putative 0.0143 0.0121 0.0575
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0044
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0009 0.0039
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0008 0.0036
Onchocerca volvulus 0.0022 0.001 0.0088
Brugia malayi 6-phosphofructokinase 0.0111 0.0091 0.0435
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.002 0.0092
Schistosoma mansoni ap endonuclease 0.002 0.0008 0.0039
Brugia malayi Pre-SET motif family protein 0.0089 0.0071 0.0341
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.008 0.0063 0.0298
Toxoplasma gondii heat shock protein HSP90 0.0143 0.0121 0.0575
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.008 0.0063 0.03
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.008 0.0063 0.0298
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Schistosoma mansoni hypothetical protein 0.0012 0 0.0002
Plasmodium falciparum phenylalanine--tRNA ligase 0.0664 0.0597 0.2859
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.008 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0063
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0009 0.0041
Plasmodium falciparum thioredoxin reductase 0.0231 0.0201 0.0959
Echinococcus multilocularis geminin 0.0337 0.0298 0.1427
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.2293 0.2089 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0009 0.0041
Trypanosoma cruzi heat shock protein 85, putative 0.0122 0.0102 0.0485
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0009 0.0044
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0009 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Mycobacterium ulcerans DNA gyrase subunit B 0.0021 0.0009 0.0001
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0008 0.0034
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Onchocerca volvulus 0.0089 0.0071 0.1067
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0091 0.0432
Onchocerca volvulus 0.0026 0.0014 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Loa Loa (eye worm) fibroinase 0.0033 0.002 0.0094
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0021 0.0009 0.0041
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0008 0.0037
Schistosoma mansoni polycystin 1-related 0.0058 0.0042 0.0202
Brugia malayi Cathepsin L-like precursor 0.0033 0.002 0.0094
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0008 0.0039
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0091 0.0438
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0091 0.0438
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0077 0.006 0.0287
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.002 0.0092
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0016 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0008 0.0036
Brugia malayi hypothetical protein 0.0237 0.0207 0.0989
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.018 0.0154 0.0147
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0044
Echinococcus multilocularis heat shock protein 90 0.0143 0.0121 0.0577
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0091 0.0435
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0051 0.0244
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 1.0936 1 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0091 0.0438
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0017 0.0079
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0007 0.0031
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0021 0.0009 0.0001
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0017 0.0079
Brugia malayi hypothetical protein 0.0058 0.0042 0.0202
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0009 0.0043
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0008 0.0037
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0021 0.0009 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0017 0.0079
Echinococcus granulosus dna polymerase eta 0.002 0.0008 0.0036
Leishmania major NADH dehydrogenase, putative 0.0021 0.0009 0.0041
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0008 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0021 0.0102
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0007 0.0031
Echinococcus granulosus glutamate synthase 0.0021 0.0009 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0016 0.0076
Brugia malayi Endoplasmin precursor 0.0143 0.0121 0.0577
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0664 0.0597 0.2861
Mycobacterium ulcerans hypothetical protein 0.0029 0.0016 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0091 0.0436
Onchocerca volvulus 0.0035 0.0021 0.0273
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0134 0.0113 0.0105
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0049 0.0034 0.0161
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0091 0.0435
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0025 0.0121
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0016 0.0073
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0009 0.0044
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0021 0.0009 0.0041
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0044 0.0211
Leishmania major hypothetical protein, conserved 0.0021 0.0009 0.0041
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0009 0.0044
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0009 0.0044
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.008 0.0063 0.0298
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0046
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0051 0.0244
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0009 0.0044
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0034 0.0162
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0091 0.0436
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0009 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0231 0.0201 0.0959
Leishmania major cathepsin L-like protease 0.0033 0.002 0.0092
Trichomonas vaginalis set domain proteins, putative 0.0702 0.0632 0.3026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Onchocerca volvulus 0.0111 0.0091 0.1389
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0231 0.0201 0.0193
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0091 0.0084
Trichomonas vaginalis ran, putative 0.0021 0.0009 0.0039
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0042 0.0202
Mycobacterium tuberculosis Conserved protein 0.0111 0.0091 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0044
Entamoeba histolytica heat shock protein 90, putative 0.0143 0.0121 0.0575
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0009 0.0082
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0021 0.0009 0.0039
Toxoplasma gondii TIM10 family protein, putative 0.0049 0.0034 0.0161
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0009 0.0041
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0008 0.0037
Echinococcus granulosus endoplasmin 0.0134 0.0113 0.0539
Schistosoma mansoni glutamate synthase 0.0021 0.0009 0.0043
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0664 0.0597 0.2861
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0008 0.0001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.008 0.0063 0.03
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0091 0.0435
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0091 0.0435
Loa Loa (eye worm) glutaminase 0.033 0.0292 0.1397
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0002 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0008 0.0034
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0442 0.2115
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0008 0.0037
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0008 0.0037
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0021 0.0009 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0009 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0002 0.0007
Brugia malayi Cathepsin L-like precursor 0.0033 0.002 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0155 0.0744
Toxoplasma gondii ABC1 family protein 0.0111 0.0091 0.0436
Leishmania major cathepsin L-like protease 0.0033 0.002 0.0092
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0068 0.0323
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0013 0.0062
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0009 0.0043
Brugia malayi DNA mismatch repair protein MutL containing protein 0.0012 0 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0104 0.0495
Entamoeba histolytica hypothetical protein 0.0026 0.0013 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0009 0.0044
Chlamydia trachomatis thioredoxin reductase 0.0021 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Brugia malayi intermediate filament protein 0.0026 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Entamoeba histolytica hypothetical protein 0.0023 0.0011 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Loa Loa (eye worm) hypothetical protein 0.0089 0.0071 0.0341
Echinococcus multilocularis glutamate synthase 0.0021 0.0009 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0091 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.018 0.0154 0.0738
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0009 0.0044
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0007 0.0031
Onchocerca volvulus 0.0058 0.0042 0.0607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0044
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0009 0.0042
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0021 0.0009 0.0069
Plasmodium falciparum heat shock protein 90, putative 0.0083 0.0066 0.0313
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0021 0.0009 0.0041
Brugia malayi phosphofructokinase 0.0111 0.0091 0.0435
Onchocerca volvulus 0.0029 0.0016 0.0185
Schistosoma mansoni cpg binding protein 0.0037 0.0023 0.0111
Echinococcus multilocularis cysteine protease 0.0033 0.002 0.0094
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0007 0.0031
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 1.0936 1 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0009 0.0041
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0021 0.0009 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0008 0.0034
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0009 0.0044
Leishmania major heat shock protein, putative 0.0095 0.0077 0.0365
Schistosoma mansoni aldehyde dehydrogenase 0.018 0.0154 0.0738
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0008 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Mycobacterium tuberculosis Conserved protein 0.0021 0.0009 0.0001
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0009 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.002 0.0092
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Mycobacterium ulcerans two component regulator - sensor kinase 0.0021 0.0009 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0009 0.0044
Echinococcus multilocularis Polycystic kidney disease protein 0.0058 0.0042 0.0202
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0059 0.0043 0.0207
Echinococcus multilocularis snurportin 1 0.0303 0.0267 0.1277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0011 0.0049
Trypanosoma cruzi major cysteine proteinase, putative 0.0098 0.0079 0.0378
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0011 0.0049
Plasmodium falciparum phenylalanine--tRNA ligase 0.0664 0.0597 0.2859
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Leishmania major mitochondrial DNA topoisomerase II 0.0021 0.0009 0.0039
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0091 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0016 0.0008
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0021 0.0009 0.0001
Loa Loa (eye worm) heat shock protein 75 0.0095 0.0077 0.0367
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0049 0.0034 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Plasmodium vivax thioredoxin reductase, putative 0.0231 0.0201 0.0959
Echinococcus granulosus cpg binding protein 0.0037 0.0023 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0021 0.0009 0.0039
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0008 0.0036
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0009 0.0044
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0134 0.0113 0.0537
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Brugia malayi Cathepsin L-like precursor 0.0033 0.002 0.0094
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0091 0.0432
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0008 0.0037
Loa Loa (eye worm) hypothetical protein 0.2293 0.2089 1
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0021 0.0009 0.0001
Loa Loa (eye worm) heat shock protein 90 0.0143 0.0121 0.0577
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Onchocerca volvulus 0.0022 0.0009 0.0082
Mycobacterium tuberculosis Conserved protein 0.0111 0.0091 0.0084
Echinococcus multilocularis MORC family CW type zinc finger protein 2B 0.0012 0 0.0002
Echinococcus multilocularis lamin dm0 0.0026 0.0014 0.0065
Toxoplasma gondii aldehyde dehydrogenase 0.018 0.0154 0.0736
Onchocerca volvulus 0.0026 0.0014 0.015
Trichomonas vaginalis receptor histidine kinase, putative 0.0021 0.0009 0.0039
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0091 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Loa Loa (eye worm) doublecortin family protein 0.0058 0.0042 0.0202
Toxoplasma gondii heat shock protein 90, putative 0.0143 0.0121 0.0575
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0016 0.0076
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0025 0.0118
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.1629 0.1481 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0091 0.0438
Echinococcus granulosus Polycystic kidney disease protein 0.0058 0.0042 0.0202
Echinococcus granulosus lamin 0.0026 0.0014 0.0065
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0664 0.0597 0.2861
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0021 0.0009 0.0039
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0009 0.0044
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0007 0.0033
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0009 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0009 0.0044
Echinococcus granulosus importin subunit beta 1 0.0028 0.0016 0.0074
Entamoeba histolytica Ran family GTPase 0.0021 0.0009 0.0039
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0007 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0009 0.0041
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0021 0.0009 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0008 0.0034
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.018 0.0154 0.0736
Treponema pallidum thioredoxin reductase (trxB) 0.0021 0.0009 0.0041
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0021 0.0009 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.002 0.0092
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0009 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0008 0.0001
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0007 0.0033
Mycobacterium tuberculosis Probable reductase 0.0526 0.0471 0.0464
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0021 0.0009 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0617 0.0554 0.2654
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0071 0.0339
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Schistosoma mansoni rab6-interacting 0.0058 0.0042 0.0202
Schistosoma mansoni hypothetical protein 0.0048 0.0034 0.0162
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0009 0.0041
Entamoeba histolytica cysteine protease, putative 0.0033 0.002 0.0092
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.0154 0.0147
Leishmania major heat shock protein 83-1 0.0143 0.0121 0.0575
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0049 0.0034 0.0163
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0044
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0039
Echinococcus granulosus expressed protein 0.0049 0.0034 0.0163
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0025 0.0118
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0009 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0113 0.0537
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0021 0.0009 0.0001
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0007 0.0031
Brugia malayi glutamate synthase 0.0021 0.0009 0.0043
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.2293 0.2089 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0044
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0013 0.0064
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0021 0.0009 0.0043
Plasmodium falciparum heat shock protein 90, putative 0.0542 0.0486 0.2326
Loa Loa (eye worm) cysteine protease 0.0033 0.002 0.0094
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0009 0.0044
Loa Loa (eye worm) ctsf protein 0.0033 0.002 0.0094
Treponema pallidum NADH oxidase 0.008 0.0063 0.0298
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0025 0.0118
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0021 0.0009 0.0041
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0021 0.0009 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0005 0.0022
Leishmania major GTP-binding protein, putative 0.0021 0.0009 0.0039
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0091 0.0084
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0039
Mycobacterium ulcerans two component sensor kinase MprB 0.0021 0.0009 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.018 0.0154 0.0738
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0009 0.0044
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0007 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0104 0.0495
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0009 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0091 0.0432
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0025 0.0121
Mycobacterium ulcerans hypothetical protein 0.0111 0.0091 0.0084
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0009 0.0044
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0034 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0009 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0063 0.0298
Loa Loa (eye worm) hypothetical protein 0.0012 0 0.0002
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0009 0.0041
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0053 0.025
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0009 0.0041
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Giardia lamblia Pms1-like protein 0.0021 0.0009 0.0039
Trypanosoma brucei heat shock protein, putative 0.0143 0.0121 0.0575
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0021 0.0009 0.0008
Brugia malayi MH2 domain containing protein 0.0121 0.0101 0.0482
Brugia malayi Pre-SET motif family protein 0.0617 0.0554 0.2654
Mycobacterium ulcerans dehydrogenase 0.0021 0.0009 0.0001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0526 0.0471 0.0464
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0009 0.0043
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0021 0.0009 0.0039
Plasmodium vivax vivapain-1 0.0017 0.0005 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0008 0.0034
Loa Loa (eye worm) hypothetical protein 0.0111 0.0091 0.0438
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0008 0.0039
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0042 0.0202
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0017 0.0079
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0007 0.0031
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0033 0.002 0.0092
Trichomonas vaginalis heat shock protein, putative 0.0104 0.0085 0.0403
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0089 0.0071 0.0341
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0009 0.0041
Leishmania major cysteine peptidase A (CPA) 0.0033 0.002 0.0092
Trichomonas vaginalis endoplasmin, putative 0.0104 0.0085 0.0403
Plasmodium falciparum importin beta, putative 0.0028 0.0016 0.0072
Plasmodium falciparum LCCL domain-containing protein 0.0058 0.0042 0.02
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0016 0.0073
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0021 0.0009 0.0043
Echinococcus multilocularis musashi 0.0026 0.0014 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0007 0.0031
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0021 0.0009 0.0041
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0007 0.0031
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0008 0.0001
Mycobacterium ulcerans hypothetical protein 0.0021 0.0009 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0008 0.0001
Plasmodium falciparum DNA gyrase subunit B 0.0021 0.0009 0.0039
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0009 0.0043
Brugia malayi Cathepsin L-like precursor 0.0033 0.002 0.0094
Schistosoma mansoni lipoxygenase 0.0222 0.0193 0.0924
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0017
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0016 0.0008
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0091 0.0432

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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