Detailed information for compound 700219

Basic information

Technical information
  • TDR Targets ID: 700219
  • Name: N-[4-[2-[2-(3-methylphenyl)-1,3-thiazol-4-yl] ethylsulfamoyl]phenyl]acetamide
  • MW: 415.529 | Formula: C20H21N3O3S2
  • H donors: 2 H acceptors: 4 LogP: 3.11 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCc1csc(n1)c1cccc(c1)C
  • InChi: 1S/C20H21N3O3S2/c1-14-4-3-5-16(12-14)20-23-18(13-27-20)10-11-21-28(25,26)19-8-6-17(7-9-19)22-15(2)24/h3-9,12-13,21H,10-11H2,1-2H3,(H,22,24)
  • InChiKey: UDAGMDVIDJVMTB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[2-[2-(3-methylphenyl)thiazol-4-yl]ethylsulfamoyl]phenyl]acetamide
  • N-[4-[2-[2-(3-methylphenyl)-4-thiazolyl]ethylsulfamoyl]phenyl]acetamide
  • N-[4-[2-[2-(3-methylphenyl)-1,3-thiazol-4-yl]ethylsulfamoyl]phenyl]ethanamide
  • ZINC04570700

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0023 0.0163 0.1212
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0392 0.3085
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0428 0.0428
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0091 0.0316
Brugia malayi endonuclease G, mitochondrial precursor 0.0165 0.2075 0.2643
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Mycobacterium ulcerans dehydrogenase/reductase 0.0012 0.0015 0.0063
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0145 0.0185
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0005 0.0007
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0043 0.0431 0.0549
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0015 0.0015
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0145 0.0145
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.0163 0.05
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0015 0.0019
Onchocerca volvulus 0.0175 0.2213 0.282
Plasmodium vivax SET domain protein, putative 0.0063 0.0697 0.292
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0015 0.0019
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0275 0.3554 0.3554
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0016 0.0005
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0145 0.0185
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Onchocerca volvulus 0.0012 0.0015 0.0019
Schistosoma mansoni dihydropteridine reductase 0.0013 0.0018 0.0018
Leishmania major pteridine reductase 1 0.0025 0.0184 0.0572
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0174 0.0739
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0277 0.1122
Schistosoma mansoni hypothetical protein 0.0593 0.7849 0.7849
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.1781 0.1781
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0145 0.0185
Mycobacterium ulcerans oxidoreductase 0.0012 0.0015 0.0063
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.0209 0.0295
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Onchocerca volvulus 0.0012 0.0015 0.0019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0277 0.0277
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0015 0.0015
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.1201 0.9696
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.0184 0.0726
Mycobacterium ulcerans oxidoreductase 0.0012 0.0015 0.0063
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0802 0.0802
Trypanosoma brucei endonuclease G, putative 0.0165 0.2075 0.6952
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0023 0.016 0.016
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Brugia malayi Heterochromatin protein 1 0.0076 0.0873 0.1112
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0043 0.0431 0.0431
Onchocerca volvulus 0.05 0.6587 0.8392
Brugia malayi hypothetical protein 0.0012 0.0015 0.0019
Onchocerca volvulus 0.0012 0.0015 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Trichomonas vaginalis set domain proteins, putative 0.05 0.6587 1
Brugia malayi hypothetical protein 0.0012 0.0015 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0145 0.0185
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0013 0.0018 0.0075
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Schistosoma mansoni lipoxygenase 0.006 0.066 0.066
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0029 0.0241 0.0241
Trypanosoma brucei oxidoreductase-like protein 0.0025 0.0184 0.0572
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0174 0.0739
Onchocerca volvulus 0.0012 0.0015 0.0019
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0043 0.0431 0.3404
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0521 0.0521
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Giardia lamblia Phosphatidylinositol-glycan biosynthesis, class O protein 0.0043 0.0431 0.3404
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0536 0.0793
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0513 0.2133
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0025 0.0184 0.0572
Schistosoma mansoni carbonyl reductase 0.0012 0.0015 0.0015
Onchocerca volvulus 0.002 0.0117 0.0149
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1238 0.4127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0277 0.0353
Schistosoma mansoni hypothetical protein 0.0041 0.0408 0.0408
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0697 0.0697
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0121 0.0161
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0016 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0232 0.2978 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0078 0.0271
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0392 0.0392
Brugia malayi chromobox protein homolog 3 0.0043 0.0423 0.0538
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0174 0.068
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0013 0.0018 0.001
Trichomonas vaginalis hypothetical protein 0.0012 0.0016 0.0002
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0145 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0521 0.0521
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0392 0.1274
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0581 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Loa Loa (eye worm) hypothetical protein 0.0275 0.3554 0.4529
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0018 0.0075
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0145 0.0145
Echinococcus multilocularis peregrin 0.0032 0.0277 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0428 0.0629
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0521 0.0664
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.1238 0.1577
Leishmania major protein tyrosine phosphatase-likie protein 0.0023 0.0163 0.05
Loa Loa (eye worm) dehydrogenase 0.0012 0.0015 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0367 0.0367
Echinococcus granulosus protein tyrosine phosphatase PRL 0.0023 0.0163 0.0163
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0145 0.0145
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0428 0.0428
Brugia malayi Latrophilin receptor protein 2 0.0017 0.008 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0277 0.1122
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Echinococcus multilocularis chromobox protein 1 0.0076 0.0873 0.0873
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.008 0.0102
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0802 0.0802
Loa Loa (eye worm) retinol dehydrogenase 12 0.0013 0.0018 0.0023
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Echinococcus multilocularis chromobox protein 2 0.0012 0.0016 0.0016
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Loa Loa (eye worm) dehydrogenase 0.0012 0.0015 0.0019
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0002
Brugia malayi AEL166Cp 0.0043 0.0431 0.0549
Loa Loa (eye worm) hypothetical protein 0.0275 0.3554 0.4529
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0002
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.002 0.0117 0.0149
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0174 0.068
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Onchocerca volvulus GPI ethanolamine phosphate transferase 2 homolog 0.0043 0.0431 0.0549
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.002 0.002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0521 0.0664
Onchocerca volvulus 0.0022 0.0145 0.0185
Schistosoma mansoni carbonyl reductase 0.0012 0.0015 0.0015
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0431 0.0549
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Echinococcus multilocularis microtubule associated protein 2 0.0753 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0078 0.0271
Schistosoma mansoni microtubule-associated protein tau 0.0753 1 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0174 0.0221
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0277 0.1122
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0174 0.0739
Loa Loa (eye worm) helicase 0.0012 0.0016 0.002
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0802 0.1022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0392 0.0392
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.002 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Brugia malayi hypothetical protein 0.0043 0.0431 0.0549
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0734 0.0935
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0043 0.0431 0.0431
Brugia malayi CHE-14 protein 0.0043 0.0428 0.0546
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0005 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0392 0.0392
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Loa Loa (eye worm) hypothetical protein 0.0108 0.1307 0.1665
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.066 0.066
Echinococcus multilocularis RUN 0.0022 0.0138 0.0138
Onchocerca volvulus 0.0275 0.3554 0.4529
Leishmania major hypothetical protein, conserved 0.0232 0.2978 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0145 0.0145
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.1238 0.1238
Echinococcus multilocularis GPCR, family 2 0.0017 0.008 0.008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0009
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0392 0.0574
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.0163 0.05
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Mycobacterium leprae hypothetical protein 0.0043 0.0431 0.1781
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0145 0.0185
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0964 0.0964
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0015 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0873 0.1306
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0018 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0392 0.0392
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0174 0.0739
Trypanosoma brucei GPI ethanolamine phosphate transferase 3, putative 0.0043 0.0431 0.1405
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0367 0.0367
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0174 0.068
Brugia malayi Bromodomain containing protein 0.0032 0.0277 0.0353
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0078 0.0271
Trypanosoma brucei endonuclease G, putative 0.0165 0.2075 0.6952
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0145 0.0185
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Echinococcus granulosus expressed conserved protein 0.0094 0.1119 0.1119
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0015 0.0063
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0016 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Leishmania major endonuclease G, putative 0.0165 0.2075 0.6952
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0186 0.2352 1
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Onchocerca volvulus 0.0012 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0163 0.2046 0.2606
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0002
Entamoeba histolytica hypothetical protein 0.0049 0.0513 0.4077
Trypanosoma cruzi hypothetical protein, conserved 0.0232 0.2978 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0392 0.0574
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.1238 0.1577
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0015 0.0015
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0013 0.0018 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0015 0.0019
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0015 0.0063
Schistosoma mansoni hypothetical protein 0.0041 0.0408 0.0408
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0367 0.0468
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0186 0.2352 1
Echinococcus granulosus peregrin 0.0032 0.0277 0.0277
Brugia malayi ecdysteroid receptor 0.0022 0.0145 0.0185
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0145 0.0145
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0392 0.0574
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0392 0.1274
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.0209 0.0209
Brugia malayi steroid hormone receptor 0.0022 0.0145 0.0185
Loa Loa (eye worm) hypothetical protein 0.0043 0.0431 0.0549
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0016 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0138 0.0138
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.016 0.016
Echinococcus granulosus transferase 0.0043 0.0431 0.0431
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0102
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.008 0.008
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0015 0.0015
Onchocerca volvulus 0.0012 0.0016 0.002
Echinococcus multilocularis ectonucleotide 0.0232 0.2971 0.2971
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0145 0.0145
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0013 0.0018 0.0012
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0016 0.0016
Onchocerca volvulus 0.0024 0.0174 0.0221
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0145 0.0185
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0138 0.0528
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0015 0.0063
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Leishmania major oxidoreductase-like protein 0.0025 0.0184 0.0572
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0174 0.0537
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0013 0.0018 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0145 0.0145
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0275 0.3554 0.3554
Loa Loa (eye worm) hypothetical protein 0.0108 0.1307 0.1665
Loa Loa (eye worm) hypothetical protein 0.0043 0.0431 0.0549
Echinococcus multilocularis chromobox protein 1 0.0076 0.0873 0.0873
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0392 0.3085
Brugia malayi hypothetical protein 0.0012 0.0016 0.002
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0186 0.2352 1
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0015 0.0019
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0016 0.0016
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0018 0.0075
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1238 0.4127
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0174 0.0221
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0026 0.0196 0.0196
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0428 0.0428
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0145 0.0185
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0071 0.0802 0.3367
Schistosoma mansoni protein tyrosine phosphatase prl 0.0023 0.0163 0.0163
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0013 0.0018 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0145 0.0185
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0013 0.0018 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0174 0.0739
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0018 0.0075
Loa Loa (eye worm) hypothetical protein 0.0024 0.0174 0.0221
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0023 0.016 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0165 0.2075 0.6952
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0521 0.0521
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0697 0.0697
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0209 0.0654
Loa Loa (eye worm) hypothetical protein 0.0055 0.0583 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0018 0.0075
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.002 0.0117 0.0346
Schistosoma mansoni protein tyrosine phosphatase prl 0.0023 0.0163 0.0163
Brugia malayi hypothetical protein 0.0022 0.0138 0.0176
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0023
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0513 0.1683
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0138 0.0138
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0466 0.0687
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0392 0.0392
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0015 0.0019
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0138 0.0528
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0145 0.0145
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0009
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.0209 0.0886
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0016 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0016 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0802 0.3409
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0423 0.0538
Echinococcus granulosus chromobox protein 1 0.0076 0.0873 0.0873
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0145 0.0145
Onchocerca volvulus 0.0108 0.1307 0.1665
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0392 0.1274
Onchocerca volvulus 0.0025 0.0184 0.0235
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0013 0.0018 0.001
Toxoplasma gondii hypothetical protein 0.002 0.0121 0.0453
Loa Loa (eye worm) hypothetical protein 0.0018 0.0091 0.0117
Plasmodium falciparum enoyl-acyl carrier reductase 0.0186 0.2352 1
Echinococcus multilocularis protein dispatched 1 0.0049 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0145 0.0145
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Brugia malayi Pre-SET motif family protein 0.0063 0.0697 0.0888
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.1201 0.1201
Schistosoma mansoni chromobox protein 0.0012 0.0016 0.0016
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0015 0.0015
Leishmania major tyrosine specific protein phosphatase, putative 0.002 0.0117 0.0346
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.1238 1
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Plasmodium falciparum phd finger protein, putative 0.0032 0.0277 0.1122
Schistosoma mansoni loxhd1 0.0022 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0018 0.0091 0.0117
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0015 0.0015
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0015 0.0019
Mycobacterium ulcerans hypothetical protein 0.0024 0.0174 0.0739
Loa Loa (eye worm) hypothetical protein 0.0054 0.0581 0.0741
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0015 0.0063
Schistosoma mansoni polycystin 1-related 0.0022 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0024 0.0174 0.0221
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0005 0.0007
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0423 0.0621
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0071 0.0802 0.0802
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0513 0.2182
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0349 0.0445
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0012
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0015 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0145 0.0145
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Brugia malayi Thrombospondin type 1 domain containing protein 0.0593 0.7849 1
Brugia malayi oxidoreductase 0.0012 0.0015 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0145 0.0185
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Trichomonas vaginalis hypothetical protein 0.0186 0.2352 0.3557
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.1253 0.1253
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Schistosoma mansoni hypothetical protein 0.0032 0.0277 0.0277
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0075
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0145 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.1238 0.1238
Echinococcus granulosus oxidoreductase 0.0012 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0015 0.0015
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0015 0.0015
Mycobacterium ulcerans hypothetical protein 0.0027 0.0209 0.0886
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0275 0.3554 0.3554
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0012
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0018 0.0075
Onchocerca volvulus 0.0012 0.0015 0.0019
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.066 0.066
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0513 0.2133
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0513 0.2133
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Echinococcus multilocularis oxidoreductase 0.0012 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0025 0.0184 0.0784
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0013 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0392 0.05
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0145 0.0145
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0521 0.0521
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0015 0.0015
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0043 0.0431 0.0549
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0016 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0016 0.0016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0174 0.068
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.0163 0.05
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.0209 0.0829
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0107 0.0136
Schistosoma mansoni rab6-interacting 0.0022 0.0138 0.0138
Schistosoma mansoni chromobox protein 0.0012 0.0016 0.0016
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0025 0.0184 0.0726
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0013 0.0018 0.0024
Echinococcus multilocularis transferase 0.0043 0.0431 0.0431
Onchocerca volvulus 0.0013 0.0018 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0174 0.0221
Loa Loa (eye worm) hypothetical protein 0.0033 0.0299 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0018 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0145 0.0185
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0015 0.0063
Echinococcus granulosus hypothetical protein 0.0012 0.0015 0.0015
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0145 0.0145
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.002 0.0025
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.016 0.016
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.1238 0.1238
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Onchocerca volvulus 0.0019 0.011 0.0141
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0138 0.0176
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0145 0.0145
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0145 0.0145
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0029 0.0241 0.0241
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0174 0.0221
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0802 0.3409
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0029 0.0241 0.0241
Onchocerca volvulus 0.0012 0.0015 0.0019
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0043 0.0431 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0423 0.0621
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0145 0.0185
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0513 0.1683
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.1575 0.6697
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Echinococcus multilocularis muscleblind protein 1 0.0163 0.2046 0.2046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0581 0.0741
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0013 0.0018 0.0012
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0015 0.0063
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0018 0.0012
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0015 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0075
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0423 0.0538
Brugia malayi jmjC domain containing protein 0.0104 0.1253 0.1596
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0024 0.0174 0.0222
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0184 0.0784
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0018 0.0023
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0175 0.2213 0.2213
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0145 0.0185
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0145 0.0145
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0138 0.0138
Onchocerca volvulus GPI ethanolamine phosphate transferase 3 homolog 0.0043 0.0431 0.0549
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0015 0.0019
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0015 0.0015
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog 0.0043 0.0431 0.0549
Schistosoma mansoni hypothetical protein 0.0017 0.008 0.008
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0275 0.3554 0.3554
Echinococcus multilocularis Endonuclease G 0.0165 0.2075 0.2075
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0697 0.0697
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0012 0.0015 0.0063
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.008 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0521 0.0521
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Brugia malayi SET domain containing protein 0.0015 0.0047 0.006
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0029 0.0241 0.0241
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0873 0.1306
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Schistosoma mansoni hypothetical protein 0.0037 0.0349 0.0349
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0002
Mycobacterium ulcerans oxidoreductase 0.0013 0.0018 0.0075
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0165 0.2075 0.8812
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.5769 0.735
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0091 0.0328
Plasmodium vivax protein tyrosine phosphatase, putative 0.0023 0.0163 0.0634
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0013 0.0018 0.0012
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0043 0.0431 0.0431
Echinococcus granulosus GPCR family 2 0.0017 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0063 0.0697 0.0888
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0016 0.002
Schistosoma mansoni hypothetical protein 0.0017 0.008 0.008
Onchocerca volvulus 0.0275 0.3554 0.4529
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0023 0.0163 0.05
Schistosoma mansoni chromobox protein 0.0076 0.0873 0.0873
Trypanosoma cruzi endonuclease G, putative 0.0165 0.2075 0.6952
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0043 0.0431 0.0549
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0232 0.2971 0.2971
Giardia lamblia PHD finger protein 15 0.0032 0.0277 0.2144
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0145 0.0145
Brugia malayi Pre-SET motif family protein 0.0439 0.5769 0.735
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.008 0.008
Brugia malayi hypothetical protein 0.0022 0.0138 0.0176
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.1575 0.1575
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0536 0.0793
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.1253 0.1253
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0392 0.05
Echinococcus granulosus Endonuclease G 0.0165 0.2075 0.2075
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0145 0.0145
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0186 0.2352 1
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0043 0.0431 0.1781
Loa Loa (eye worm) hypothetical protein 0.0019 0.01 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Schistosoma mansoni hypothetical protein 0.0017 0.008 0.008
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0186 0.2352 1
Brugia malayi CHD4 protein 0.0012 0.0016 0.002
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0012 0.0015 0.0063
Brugia malayi Trypsin family protein 0.0108 0.1307 0.1665
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0015 0.0015
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0043 0.0431 0.0431
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.1575 0.1575
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0165 0.2075 0.6952
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog 0.0043 0.0431 0.0549
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0015 0.0063
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0184 0.0784
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0277 0.0353
Schistosoma mansoni carbonyl reductase 0.0012 0.0015 0.0015
Leishmania major ethanolamine phosphotransferase, putative 0.0043 0.0431 0.1405
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0016 0.0016
Brugia malayi Doublecortin family protein 0.0022 0.0138 0.0176
Schistosoma mansoni chromobox protein 0.0076 0.0873 0.0873
Schistosoma mansoni hypothetical protein 0.0017 0.008 0.008
Brugia malayi hypothetical protein 0.0012 0.0005 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Onchocerca volvulus 0.0012 0.0016 0.002
Brugia malayi Protein cec-1. 0.0012 0.0016 0.002
Brugia malayi Muscleblind-like protein 0.0163 0.2046 0.2606
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0145 0.0185
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0145 0.0145
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0071 0.0802 0.2657
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0513 0.2133
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0005 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.1575 0.6676
Trypanosoma cruzi endonuclease G, putative 0.0165 0.2075 0.6952
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0145 0.0145
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0013 0.0018 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Mycobacterium ulcerans hypothetical protein 0.0027 0.0209 0.0886
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0043 0.0431 0.3404
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Mycobacterium ulcerans dehydrogenase 0.0012 0.0015 0.0063
Echinococcus granulosus Chromobox protein 3 0.0012 0.0016 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0145 0.0145
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0016 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0521 0.0521
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0015 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.1575 0.6697
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0013 0.0018 0.0012
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.1781 0.1781
Onchocerca volvulus 0.0012 0.0015 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0002
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0015 0.0015
Brugia malayi nuclear hormone receptor 0.0022 0.0145 0.0185
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0016 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0145 0.0145
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0091 0.0389
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0016 0.0005
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.0873 0.1112
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0805 0.1025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0349 0.0445
Onchocerca volvulus 0.0022 0.0138 0.0176
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0013 0.0018 0.001
Brugia malayi jmjC domain containing protein 0.0039 0.0367 0.0468
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.002 0.0117 0.0346
Plasmodium falciparum protein tyrosine phosphatase 0.0023 0.0163 0.0634
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0581 0.0741
Schistosoma mansoni lipoxygenase 0.0022 0.0138 0.0138
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0015 0.0015
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0174 0.0537
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0174 0.13
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.002 0.0117 0.0117
Schistosoma mansoni kinase 0.0052 0.0554 0.0554
Echinococcus granulosus chromobox protein 2 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0091 0.0117
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0013 0.0018 0.0012
Echinococcus granulosus L aminoadipate semialdehyde 0.0175 0.2213 0.2213
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Trypanosoma brucei endonuclease G, putative 0.0165 0.2075 0.6952
Schistosoma mansoni hypothetical protein 0.0022 0.0138 0.0138
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0445 0.0445
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.1238 0.4127
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0186 0.2352 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0513 0.2123
Loa Loa (eye worm) hypothetical protein 0.0018 0.0091 0.0117
Echinococcus multilocularis sortilin receptor 0.0016 0.0064 0.0064
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0022 0.0138 0.0176
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0513 0.2133
Loa Loa (eye worm) hypothetical protein 0.0275 0.3554 0.4529
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0029 0.0241 0.0241
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0013 0.0018 0.0075
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Brugia malayi hypothetical protein 0.0043 0.0431 0.0549
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0174 0.13
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.1238 0.1577
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0043 0.0431 0.0431
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0043 0.0431 0.0431
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.1575 0.5267
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0145 0.0185
Brugia malayi PHD-finger family protein 0.0032 0.0277 0.0353
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.1201 0.1201
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0013 0.0018 0.0012
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Schistosoma mansoni hypothetical protein 0.0043 0.0431 0.0431
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0023 0.0163 0.05
Schistosoma mansoni hypothetical protein 0.0043 0.0431 0.0431
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0163 0.2046 0.2606
Echinococcus granulosus Chromo domain 0.0012 0.0016 0.0016
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0015 0.0015
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0016 0.002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0018 0.0012
Echinococcus granulosus ectonucleotide 0.0232 0.2971 0.2971
Mycobacterium ulcerans short-chain type oxidoreductase 0.0012 0.0015 0.0063
Loa Loa (eye worm) hypothetical protein 0.0175 0.2213 0.282
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0043 0.0431 0.0431
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.1307 0.1307
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0016 0.0005
Echinococcus multilocularis muscleblind protein 0.0163 0.2046 0.2046
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0145 0.0185
Brugia malayi nuclear receptor NHR-88 0.0022 0.0145 0.0185
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0445 0.0445
Trypanosoma cruzi protein tyrosine phosphatase PRL 0.0023 0.0163 0.05
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0255 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1238 0.1861
Mycobacterium ulcerans carveol-like dehydrogenase 0.0012 0.0015 0.0063
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0184 0.0784
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0186 0.2352 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.0865 0.0865
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0255 0.0365
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0013 0.0018 0.0018
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0466 0.0594
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0013 0.0018 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0466 0.0687
Onchocerca volvulus 0.0012 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0091 0.0117
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0015 0.0015
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0209 0.0654
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.008 0.0102
Schistosoma mansoni hypothetical protein 0.0041 0.0408 0.0408
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.008 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0005 0.0007
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0023 0.0163 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0593 0.7849 1
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0015 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0174 0.0537
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0078 0.0271
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0174 0.0739
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0145 0.0185
Giardia lamblia Kinase, PLK 0.0103 0.1238 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0145 0.0145
Leishmania major protein tyrosine phosphatase-like protein 0.0023 0.0163 0.05
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0275 0.3554 0.4529
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0013 0.0018 0.0075
Echinococcus multilocularis L aminoadipate semialdehyde 0.0175 0.2213 0.2213
Trypanosoma brucei phosphatase of regenerating liver-type phosphatase, putative 0.0023 0.0163 0.05
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0145 0.0185
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0277 0.0277
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0145 0.0185
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0697 0.292
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0392 0.0392
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0174 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Onchocerca volvulus 0.0022 0.0138 0.0176
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Echinococcus multilocularis protein tyrosine phosphatase PRL 0.0023 0.0163 0.0163
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0012 0.0016 0.0016
Brugia malayi nuclear receptor RXR 0.0012 0.0005 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0697 0.0697
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.1575 0.6676
Brugia malayi hypothetical protein 0.0012 0.0005 0.0007
Trypanosoma brucei pteridine reductase 1 0.0013 0.0018 0.001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0145 0.0185
Schistosoma mansoni hypothetical protein 0.0043 0.0431 0.0431
Onchocerca volvulus 0.0033 0.0299 0.038
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.01 0.1201 0.153
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0015 0.0015
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0138 0.0138
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0513 0.2133
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0145 0.0185
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.002 0.0117 0.0117
Schistosoma mansoni coup transcription factor 0.0022 0.0145 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0145 0.0185
Loa Loa (eye worm) oxidoreductase 0.0013 0.0018 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0521 0.0521
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0016 0.0005
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0174 0.13
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0002
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0016 0.002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Trypanosoma brucei polo-like protein kinase 0.0103 0.1238 0.4127
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.1575 0.1575
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0513 0.5
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0165 0.2075 0.6952
Schistosoma mansoni rab6-interacting 0.0022 0.0138 0.0138
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.1575 0.6697
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0002
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0209 0.0654
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0091 0.0328
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.0209 0.0886
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Onchocerca volvulus Sepiapterin reductase homolog 0.0012 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0145 0.0145
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.1575 0.1575
Schistosoma mansoni hypothetical protein 0.0041 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0697 0.0697
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0013 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0053 0.0559 0.0712
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0392 0.1274
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0232 0.2971 0.2971
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.0209 0.0886
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Loa Loa (eye worm) hypothetical protein 0.0043 0.0428 0.0546
Onchocerca volvulus 0.0097 0.1155 0.1472
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Loa Loa (eye worm) hypothetical protein 0.0043 0.0431 0.0549
Echinococcus granulosus RUN 0.0022 0.0138 0.0138
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0145 0.0185
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0392 0.0392
Onchocerca volvulus 0.0075 0.0865 0.1102
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0015 0.0015
Mycobacterium tuberculosis Conserved protein 0.0027 0.0209 0.0829
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0002
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0013 0.0018 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0018 0.0075
Onchocerca volvulus 0.0593 0.7849 1
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0232 0.2971 0.3786
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0392 0.0392
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0513 0.2133
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.1221 0.1221
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0145 0.0145
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.0209 0.0209
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0012 0.0015 0.0019
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0015 0.0015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0016 0.0016
Echinococcus multilocularis Chromo domain 0.0012 0.0016 0.0016
Schistosoma mansoni patched 1 0.0043 0.0428 0.0428
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.1201 0.153
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0513 0.2182
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0175 0.2213 0.282
Mycobacterium ulcerans hypothetical protein 0.0043 0.0431 0.1832
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0024 0.0174 0.0222
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0023 0.0163 0.05
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0091 0.0328
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0023 0.016 0.016
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0138 0.0138
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Loa Loa (eye worm) hypothetical protein 0.0022 0.0138 0.0176
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0145 0.0145
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.1307 0.1307
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0005 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0015 0.0063
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0015 0.0019
Echinococcus granulosus muscleblind protein 0.0163 0.2046 0.2046
Onchocerca volvulus Alhambra homolog 0.0032 0.0277 0.0353
Schistosoma mansoni endonuclease related 0.0165 0.2075 0.2075
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0015 0.0063
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0145 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0145 0.0185
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0016 0.0016
Onchocerca volvulus 0.0012 0.0015 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0145 0.0145
Schistosoma mansoni hypothetical protein 0.0043 0.0431 0.0431
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0016 0.002
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0275 0.3554 0.3554
Echinococcus multilocularis expressed conserved protein 0.0094 0.1119 0.1119
Trypanosoma brucei hypothetical protein, conserved 0.0232 0.2978 1
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0145 0.0185
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0145 0.0185
Onchocerca volvulus 0.0012 0.0015 0.0019
Echinococcus multilocularis protein patched 0.0043 0.0428 0.0428
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0428 0.0546
Loa Loa (eye worm) oxidoreductase 0.0012 0.0015 0.0019
Echinococcus granulosus chromobox protein 1 0.0076 0.0873 0.0873
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.002
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0666 0.0666
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0009
Echinococcus granulosus hypothetical protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0145 0.0185
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0016 0.0016

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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