Detailed information for compound 788753

Basic information

Technical information
  • TDR Targets ID: 788753
  • Name: N-(2-methoxy-5-methylphenyl)-3-[3-(4-methoxyp henyl)-1,2,4-oxadiazol-5-yl]propanamide
  • MW: 367.398 | Formula: C20H21N3O4
  • H donors: 1 H acceptors: 3 LogP: 3.21 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1noc(n1)CCC(=O)Nc1cc(C)ccc1OC
  • InChi: 1S/C20H21N3O4/c1-13-4-9-17(26-3)16(12-13)21-18(24)10-11-19-22-20(23-27-19)14-5-7-15(25-2)8-6-14/h4-9,12H,10-11H2,1-3H3,(H,21,24)
  • InChiKey: IVGJTCNPDPGARV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-methoxy-5-methyl-phenyl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide
  • N-(2-methoxy-5-methyl-phenyl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propionamide
  • EU-0058868

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0138 0.0136
Trypanosoma brucei epsilon tubulin 0.0457 0.2776 0.3396
Echinococcus granulosus peroxisome assembly protein 26 0.0526 0.3206 0.3403
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0123 0.0678 0.082
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0026 0.0064 0.0057
Loa Loa (eye worm) tubulin alpha 2 0.0327 0.1958 0.2378
Trichomonas vaginalis histone deacetylase, putative 0.1313 0.8154 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0472 0.0493
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0026 0.0064 0.0047
Plasmodium falciparum alpha tubulin 1 0.0526 0.3206 0.3924
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0026 0.0064 0.0047
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0094 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0094 0.0116
Entamoeba histolytica tubulin alpha-1 chain 0.0526 0.3206 0.3912
Brugia malayi hypoxia-induced factor 1 0.0156 0.0885 0.1075
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Echinococcus multilocularis neuropeptide s receptor 0.0484 0.2945 0.2938
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0094 0.0116
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0026 0.0064 0.0047
Echinococcus multilocularis tubulin alpha chain 0.0526 0.3206 0.3199
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0143 0.0801 0.1668
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0112 0.0604 0.0632
Entamoeba histolytica hypothetical protein 0.0321 0.192 0.233
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0157 0.089 0.108
Leishmania major hypothetical protein, conserved 0.0026 0.0064 0.0066
Echinococcus granulosus histone deacetylase 8 0.041 0.2482 0.2632
Mycobacterium ulcerans hypothetical protein 0.0021 0.0034 0.0216
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Loa Loa (eye worm) tubulin gamma chain 0.0457 0.2776 0.3383
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0327 0.1958 0.2402
Brugia malayi Pax transcription factor protein 2 0.0752 0.4628 0.5671
Echinococcus multilocularis Smad4 0.0056 0.0254 0.0244
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0612 0.075
Schistosoma mansoni single-minded 0.0051 0.022 0.0224
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0025 0.006 0.0055
Brugia malayi TAZ zinc finger family protein 0.0113 0.0611 0.0739
Echinococcus granulosus jun protein 0.0087 0.0451 0.0469
Trichomonas vaginalis tubulin beta chain, putative 0.0526 0.3206 0.3931
Toxoplasma gondii histone deacetylase HDAC4 0.041 0.2482 0.3036
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0112 0.0604 0.5103
Onchocerca volvulus 0.0043 0.0176 0.0308
Brugia malayi Histone deacetylase 1 0.1313 0.8154 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0138 0.0136
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0026 0.0064 0.0066
Loa Loa (eye worm) isocitrate dehydrogenase 0.0123 0.0678 0.0802
Loa Loa (eye worm) hypothetical protein 0.0032 0.0105 0.0098
Echinococcus multilocularis tubulin delta chain 0.0199 0.115 0.1142
Echinococcus multilocularis neuropeptide receptor A26 0.0484 0.2945 0.2938
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0026 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0081 0.041 0.0473
Schistosoma mansoni cpg binding protein 0.0032 0.0101 0.0097
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0062 0.0293 0.0302
Brugia malayi Histone deacetylase family protein 0.0527 0.3217 0.3937
Brugia malayi Muscleblind-like protein 0.0155 0.0877 0.1065
Echinococcus granulosus Tubulin beta 2C chain 0.0756 0.4655 0.4946
Loa Loa (eye worm) hypothetical protein 0.0031 0.0097 0.0088
Entamoeba histolytica hypothetical protein 0.0321 0.192 0.233
Echinococcus granulosus histone deacetylase 6 0.0553 0.3377 0.3585
Schistosoma mansoni tubulin subunit delta 0.0199 0.115 0.1214
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0062 0.0293 0.0329
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0073 0.0077
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.0293 0.0564
Trichomonas vaginalis tubulin beta chain, putative 0.0526 0.3206 0.3931
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1313 0.8154 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0138 0.0918
Trypanosoma brucei histone deacetylase, putative 0.0527 0.3217 0.3937
Echinococcus multilocularis thyroid hormone receptor alpha 0.0274 0.1622 0.1614
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.1265 0.1524
Schistosoma mansoni flap endonuclease-1 0.0024 0.0056 0.005
Schistosoma mansoni hypothetical protein 0.0071 0.0348 0.036
Echinococcus granulosus tubulin alpha 3 chain 0.0526 0.3206 0.3403
Giardia lamblia Hypothetical protein 0.0026 0.0064 0.0066
Loa Loa (eye worm) histone deacetylase 1 0.1313 0.8154 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0092 0.0481 0.0578
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0138 0.0157
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0064 0.0078
Loa Loa (eye worm) nuclear hormone receptor 0.0062 0.0293 0.0329
Brugia malayi Dihydrofolate reductase 0.0045 0.0189 0.022
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.037 0.0442
Brugia malayi Cell division protein ftsZ 0.0199 0.115 0.14
Entamoeba histolytica tubulin alpha chain, putative 0.0526 0.3206 0.3912
Echinococcus multilocularis tubulin alpha 3 chain 0.0526 0.3206 0.3199
Echinococcus multilocularis tubulin alpha chain 0.0526 0.3206 0.3199
Brugia malayi Thioredoxin reductase 0.0049 0.0211 0.0247
Echinococcus multilocularis tubulin alpha 1C chain 0.0526 0.3206 0.3199
Leishmania major epsilon tubulin, putative 0.0457 0.2776 0.3396
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.0293 0.0302
Schistosoma mansoni tubulin subunit alpha 0.0199 0.115 0.1214
Echinococcus multilocularis nuclear receptor nhr 48 0.0062 0.0293 0.0284
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Plasmodium vivax SET domain protein, putative 0.0032 0.0102 0.0113
Loa Loa (eye worm) BEN-1 protein 0.0756 0.4655 0.5695
Trypanosoma brucei epsilon tubulin 0.0457 0.2776 0.3396
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0157 0.089 0.108
Plasmodium vivax tubulin gamma chain, putative 0.0457 0.2776 0.3396
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0612 0.5176
Loa Loa (eye worm) hypoxia-induced factor 1 0.0156 0.0885 0.1057
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0211 0.1446
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0131 0.0724 0.0761
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0756 0.4655 0.465
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0073 0.0077
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.006 0.0042
Schistosoma mansoni smad1 5 8 and 0.0056 0.0254 0.026
Plasmodium falciparum glutathione reductase 0.0049 0.0211 0.0247
Trypanosoma cruzi epsilon tubulin, putative 0.0457 0.2776 0.3396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0143 0.0801 0.0953
Brugia malayi Pre-SET motif family protein 0.0217 0.1265 0.1541
Brugia malayi nuclear receptor RXR 0.0081 0.041 0.0492
Onchocerca volvulus 0.0143 0.0801 0.1668
Brugia malayi hypothetical protein 0.0062 0.0293 0.0348
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0176 0.0177
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0143 0.0801 0.0792
Plasmodium falciparum histone acetyltransferase GCN5 0.0083 0.0422 0.0506
Schistosoma mansoni nuclear receptor 0.0062 0.0293 0.0302
Schistosoma mansoni tubulin subunit alpha 0.0526 0.3206 0.3403
Loa Loa (eye worm) hypothetical protein 0.1313 0.8154 1
Loa Loa (eye worm) tubulin beta chain 0.0756 0.4655 0.5695
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0143 0.0801 0.0953
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0293 0.0302
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0293 0.0302
Onchocerca volvulus 0.0247 0.1452 0.3086
Loa Loa (eye worm) histone deacetylase 3 0.1313 0.8154 1
Echinococcus granulosus tubulin delta chain 0.0199 0.115 0.1214
Loa Loa (eye worm) tubulin alpha 2 0.0327 0.1958 0.2378
Onchocerca volvulus 0.0068 0.0333 0.065
Entamoeba histolytica hypothetical protein 0.0321 0.192 0.233
Brugia malayi thymidylate synthase 0.0112 0.0604 0.0729
Echinococcus granulosus beta tubulin 0.0756 0.4655 0.4946
Treponema pallidum cell division protein FtsZ 0.0199 0.115 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0026 0.0138
Leishmania major cytochrome p450-like protein 0.0024 0.0052 0.0052
Echinococcus multilocularis histone deacetylase 8 0.041 0.2482 0.2475
Giardia lamblia Histone acetyltransferase GCN5 0.0083 0.0422 0.0506
Loa Loa (eye worm) hypothetical protein 0.0037 0.0138 0.0138
Schistosoma mansoni histone deacetylase hda2 0.041 0.2482 0.2632
Trichomonas vaginalis tubulin beta chain, putative 0.0526 0.3206 0.3931
Echinococcus multilocularis jun protein 0.0087 0.0451 0.0441
Leishmania major delta tubulin, putative 0.0199 0.115 0.14
Loa Loa (eye worm) hypothetical protein 0.0081 0.041 0.0473
Toxoplasma gondii ABC1 family protein 0.0037 0.0138 0.0157
Brugia malayi latrophilin 2 splice variant baaae 0.0032 0.0105 0.0117
Schistosoma mansoni histone deacetylase 4 5 0.0527 0.3217 0.3414
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0143 0.0801 0.0842
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0123 0.0678 0.0711
Trichomonas vaginalis BRCA1-associated protein, putative 0.0026 0.0064 0.0078
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0056 0.0254 0.026
Echinococcus multilocularis beta tubulin 0.0756 0.4655 0.465
Echinococcus multilocularis Tubulin beta 2C chain 0.0756 0.4655 0.465
Schistosoma mansoni nuclear receptor nhr-48 0.0062 0.0293 0.0302
Trypanosoma brucei beta tubulin 0.0756 0.4655 0.5704
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0045 0.0189 0.1284
Echinococcus granulosus tubulin beta 4A class IVa 0.0756 0.4655 0.4946
Echinococcus multilocularis Tubulin beta 2C chain 0.0756 0.4655 0.465
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0211 0.0229
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0112 0.0109
Trichomonas vaginalis tubulin gamma chain, putative 0.0457 0.2776 0.3404
Toxoplasma gondii alpha tubulin TUBA1 0.0526 0.3206 0.3924
Brugia malayi MH2 domain containing protein 0.0819 0.505 0.6189
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0083 0.0102
Schistosoma mansoni histone deacetylase 1 2 3 0.041 0.2482 0.2632
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0403 0.0483
Toxoplasma gondii alpha-tubulin I, putative 0.0526 0.3206 0.3924
Brugia malayi orphan nuclear receptor NR2E1 0.0062 0.0293 0.0348
Echinococcus granulosus tubulin alpha 3 chain 0.0526 0.3206 0.3403
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0052 0.0374
Brugia malayi Tubulin alpha-2 chain 0.0526 0.3206 0.3924
Trichomonas vaginalis tubulin epsilon chain, putative 0.0756 0.4655 0.5709
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0026 0.0064 0.0066
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0094 0.2154
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0064 0.0078
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0026 0.0113
Echinococcus multilocularis chromobox protein 1 0.0072 0.0357 0.0348
Loa Loa (eye worm) tubulin beta-2A chain 0.0756 0.4655 0.5695
Schistosoma mansoni RAR-like nuclear receptor 0.0143 0.0801 0.0842
Loa Loa (eye worm) hypothetical protein 0.0112 0.0604 0.0711
Trichomonas vaginalis histone deacetylase, putative 0.1313 0.8154 1
Entamoeba histolytica histone deacetylase, putative 0.1313 0.8154 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0123 0.0678 0.0669
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0236 0.029
Toxoplasma gondii histone deacetylase HDAC1 0.0527 0.3217 0.3937
Echinococcus multilocularis histone deacetylase 7 0.0527 0.3217 0.321
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.001 0.0012
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0026 0.0019
Echinococcus multilocularis hypothetical protein 0.0526 0.3206 0.3199
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0143 0.0801 0.0971
Schistosoma mansoni smad1 5 8 and 0.0056 0.0254 0.026
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0157 0.089 0.108
Mycobacterium tuberculosis Hypothetical protein 0.0053 0.0236 0.1626
Brugia malayi Tubulin gamma chain 0.0457 0.2776 0.3396
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0026 0.0138
Brugia malayi Smad1 0.0056 0.0254 0.0299
Schistosoma mansoni lamin 0.0028 0.0079 0.0073
Leishmania major hypothetical protein, conserved 0.0026 0.0064 0.0066
Loa Loa (eye worm) tubulin alpha chain 0.0526 0.3206 0.3912
Loa Loa (eye worm) MH2 domain-containing protein 0.0056 0.0254 0.0281
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0143 0.0801 0.0792
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Trypanosoma cruzi epsilon tubulin, putative 0.0457 0.2776 0.3396
Entamoeba histolytica acetyltransferase, GNAT family 0.0083 0.0422 0.0488
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0199 0.115 1
Schistosoma mansoni hypothetical protein 0.1512 0.9403 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.037 0.0423
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0321 0.192 0.1912
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0606 0.4282
Schistosoma mansoni hypothetical protein 0.1512 0.9403 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0026 0.0064 0.0066
Echinococcus granulosus CREB binding protein 0.0072 0.0358 0.0371
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0026 0.0064 0.0054
Echinococcus multilocularis tubulin alpha chain 0.0526 0.3206 0.3199
Echinococcus granulosus tubulin alpha 0.0457 0.2776 0.2945
Leishmania major histone deacetylase, putative 0.0527 0.3217 0.3937
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0045 0.0189 0.1383
Echinococcus granulosus lamin 0.0028 0.0079 0.0073
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0199 0.115 0.1411
Brugia malayi Tubulin alpha chain 0.0526 0.3206 0.3924
Trypanosoma brucei tubulin gamma chain 0.0457 0.2776 0.3396
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0073 0.0063
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0612 0.0721
Loa Loa (eye worm) steroid hormone receptor 0.0143 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Echinococcus granulosus histone deacetylase 0.0527 0.3217 0.3414
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0612 0.528
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0293 0.0302
Schistosoma mansoni Smad4 0.0056 0.0254 0.026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0102 0.0098
Schistosoma mansoni ap endonuclease 0.002 0.0026 0.0017
Echinococcus multilocularis chromobox protein 1 0.0072 0.0357 0.0348
Brugia malayi nuclear receptor RXR 0.0062 0.0293 0.0348
Brugia malayi MH2 domain containing protein 0.0056 0.0254 0.0299
Trypanosoma brucei histone deacetylase 1 0.1313 0.8154 1
Toxoplasma gondii endonuclease IV APN 0.008 0.0403 0.0483
Trypanosoma brucei histone deacetylase 4 0.0527 0.3217 0.3937
Trichomonas vaginalis tubulin beta chain, putative 0.0526 0.3206 0.3931
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0064 0.0066
Schistosoma mansoni hypothetical protein 0.0033 0.0112 0.0109
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0026 0.0064 0.0066
Echinococcus multilocularis cpg binding protein 0.0032 0.0101 0.0091
Trichomonas vaginalis tubulin gamma chain, putative 0.0199 0.115 0.1411
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0612 0.0721
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0026 0.0064 0.0047
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0094 0.0104
Brugia malayi histone deacetylase 3 (HD3) 0.1313 0.8154 1
Echinococcus multilocularis musashi 0.0028 0.0079 0.0069
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0026 0.0138
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0472 0.0493
Giardia lamblia Alpha-tubulin 0.0526 0.3206 0.3924
Brugia malayi Tubulin beta chain 0.0259 0.1528 0.1865
Loa Loa (eye worm) alpha-tubulin 0.0526 0.3206 0.3912
Giardia lamblia Alpha-tubulin 0.0526 0.3206 0.3924
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Echinococcus multilocularis tubulin gamma 1 chain 0.0457 0.2776 0.2769
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0052 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0143 0.0801 0.0971
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0073 0.0077
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0112 0.0604 0.0711
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0612 0.0603
Brugia malayi chromobox protein homolog 3 0.0041 0.0158 0.0182
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0157 0.089 0.108
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0123 0.0678 0.082
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0094 0.0116
Trichomonas vaginalis tubulin alpha chain, putative 0.0259 0.1528 0.1874
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0124 0.0685 0.4845
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0211 0.0247
Trypanosoma brucei alpha tubulin 0.0526 0.3206 0.3924
Echinococcus multilocularis histone deacetylase 0.0527 0.3217 0.321
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0123 0.0678 0.0669
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0177 0.0217
Echinococcus granulosus histone deacetylase 6 0.0527 0.3217 0.3414
Plasmodium falciparum thioredoxin reductase 0.0049 0.0211 0.0247
Schistosoma mansoni tubulin subunit beta 0.0756 0.4655 0.4946
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0403 0.0483
Loa Loa (eye worm) dihydrofolate reductase 0.0045 0.0189 0.0201
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0094 0.0104
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Plasmodium vivax tubulin epsilon chain, putative 0.0457 0.2776 0.3396
Brugia malayi Histone deacetylase family protein 0.0527 0.3217 0.3937
Loa Loa (eye worm) hypothetical protein 0.041 0.2482 0.3022
Brugia malayi nuclear hormone receptor 0.0143 0.0801 0.0971
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0064 0.0078
Echinococcus granulosus histone deacetylase 3 0.1313 0.8154 0.8671
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Brugia malayi tubulin alpha-2 chain 0.0526 0.3206 0.3924
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0102 0.0098
Echinococcus granulosus mothers against decapentaplegic 2 0.0025 0.006 0.0053
Schistosoma mansoni tubulin subunit beta 0.0199 0.115 0.1214
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0138 0.0157
Trichomonas vaginalis set domain proteins, putative 0.0247 0.1452 0.1781
Toxoplasma gondii histone deacetylase HDAC2 0.1313 0.8154 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0092 0.0481 0.0589
Echinococcus granulosus muscleblind protein 0.0155 0.0877 0.0924
Loa Loa (eye worm) histone deacetylase 0.0527 0.3217 0.3926
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0143 0.0801 0.0842
Trypanosoma brucei trypanothione reductase 0.0049 0.0211 0.0247
Giardia lamblia Beta tubulin 0.0756 0.4655 0.5704
Echinococcus granulosus cpg binding protein 0.0032 0.0101 0.0097
Brugia malayi MH1 domain containing protein 0.0056 0.0254 0.0299
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0403 0.3302
Trypanosoma cruzi zeta tubulin, putative 0.0199 0.115 0.14
Trypanosoma cruzi tubulin delta chain 0.0199 0.115 0.14
Brugia malayi intermediate filament protein 0.0028 0.0079 0.0085
Loa Loa (eye worm) hypothetical protein 0.0025 0.006 0.0042
Brugia malayi ecdysteroid receptor 0.0143 0.0801 0.0971
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.0451 0.0441
Trichomonas vaginalis tubulin epsilon chain, putative 0.0199 0.115 0.1411
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.037 0.0442
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0143 0.0801 0.0842
Brugia malayi histone deacetylase 1 (HD1) 0.1313 0.8154 1
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0138 0.0169
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0293 0.0284
Schistosoma mansoni CREB-binding protein 2 0.0113 0.0611 0.064
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0606 0.4282
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0357 0.0438
Brugia malayi dihydrofolate reductase family protein 0.0045 0.0189 0.022
Echinococcus granulosus BRCA1 associated protein 0.0026 0.0064 0.0057
Loa Loa (eye worm) glutathione reductase 0.0049 0.0211 0.0229
Loa Loa (eye worm) tubulin alpha 2 0.0068 0.0333 0.0378
Trypanosoma brucei zeta tubulin, putative 0.0199 0.115 0.14
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0143 0.0801 0.0971
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0064 0.0066
Trichomonas vaginalis bromodomain-containing protein, putative 0.0092 0.0481 0.0589
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0081 0.041 0.0426
Echinococcus granulosus flap endonuclease 1 0.0027 0.0073 0.0067
Mycobacterium tuberculosis Cell division protein FtsZ 0.0199 0.115 0.8184
Brugia malayi Tubulin beta chain 0.0199 0.115 0.14
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0026 0.0064 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0143 0.0801 0.0971
Echinococcus granulosus tubulin alpha chain 0.0526 0.3206 0.3403
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0112 0.0103
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Mycobacterium tuberculosis Conserved protein 0.0037 0.0138 0.0918
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0081 0.041 0.0401
Brugia malayi beta-lactamase family protein 0.0037 0.0138 0.0157
Plasmodium vivax glutathione reductase, putative 0.0049 0.0211 0.0247
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Echinococcus granulosus lamin dm0 0.0028 0.0079 0.0073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0011
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0073 0.0089
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0224 0.0228
Plasmodium falciparum tubulin beta chain 0.0756 0.4655 0.5704
Brugia malayi Cytochrome P450 family protein 0.0024 0.0052 0.0052
Echinococcus multilocularis lamin 0.0028 0.0079 0.0069
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0123 0.0678 0.4793
Toxoplasma gondii beta-1 tubulin, putative 0.0756 0.4655 0.5704
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0138 0.0169
Brugia malayi histone deacetylase 11 0.041 0.2482 0.3036
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0143 0.0801 0.0842
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Schistosoma mansoni transcription factor LCR-F1 0.0321 0.192 0.2034
Trypanosoma brucei epsilon tubulin 0.0457 0.2776 0.3396
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0026 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0267 0.158 0.1913
Trypanosoma cruzi histone deacetylase, putative 0.041 0.2482 0.3036
Echinococcus granulosus tubulin epsilon chain 0.0457 0.2776 0.2945
Mycobacterium tuberculosis Conserved protein 0.0037 0.0138 0.0918
Schistosoma mansoni smad1 5 8 and 0.0056 0.0254 0.026
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0026 0.0031
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0164 0.0936 0.0928
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0124 0.0685 0.4845
Schistosoma mansoni tubulin subunit gamma 0.0457 0.2776 0.2945
Brugia malayi beta-lactamase family protein 0.0037 0.0138 0.0157
Plasmodium vivax tubulin alpha chain, putative 0.0526 0.3206 0.3924
Brugia malayi conserved hypotetical protein 0.0062 0.0293 0.0348
Brugia malayi Calcitonin receptor-like protein seb-1 0.0047 0.0198 0.0232
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0143 0.0801 0.0971
Brugia malayi Flap endonuclease-1 0.0027 0.0073 0.0077
Echinococcus granulosus smad 0.0056 0.0254 0.026
Brugia malayi phosphofructokinase 0.0113 0.0612 0.0739
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0123 0.0678 0.0669
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.037 0.0442
Trypanosoma brucei tubulin delta chain 0.0199 0.115 0.14
Loa Loa (eye worm) tubulin alpha-3 chain 0.0267 0.158 0.1913
Brugia malayi Heterochromatin protein 1 0.0072 0.0357 0.0427
Brugia malayi MH2 domain containing protein 0.0025 0.006 0.0061
Mycobacterium ulcerans endonuclease IV 0.008 0.0403 0.3447
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Trypanosoma cruzi zeta tubulin, putative 0.0199 0.115 0.14
Loa Loa (eye worm) hypothetical protein 0.008 0.0403 0.0464
Echinococcus granulosus tumor protein p63 0.0351 0.2107 0.2233
Trypanosoma cruzi tubulin gamma chain 0.0457 0.2776 0.3396
Loa Loa (eye worm) hypothetical protein 0.0037 0.0138 0.0138
Brugia malayi Tubulin alpha chain 0.0199 0.115 0.14
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.037 0.0442
Schistosoma mansoni tubulin subunit beta 0.0756 0.4655 0.4946
Brugia malayi hypothetical protein 0.0169 0.0967 0.1176
Echinococcus multilocularis CREB binding protein 0.0017 0.0011 0.0002
Loa Loa (eye worm) hypothetical protein 0.0081 0.041 0.0473
Mycobacterium tuberculosis Probable oxidoreductase 0.0124 0.0685 0.4845
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.0293 0.0564
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0138 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0199 0.115 0.1411
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0143 0.0801 0.0971
Schistosoma mansoni thyroid hormone receptor 0.0274 0.1622 0.1716
Brugia malayi 6-phosphofructokinase 0.0113 0.0612 0.0739
Loa Loa (eye worm) hypothetical protein 0.0037 0.0138 0.0138
Plasmodium falciparum flap endonuclease 1 0.0027 0.0073 0.0077
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0143 0.0801 0.0792
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0123 0.0678 0.0669
Leishmania major histone deacetylase, putative 0.1313 0.8154 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0472 0.0463
Trichomonas vaginalis tubulin alpha chain, putative 0.0259 0.1528 0.1874
Schistosoma mansoni jun-related protein 0.0071 0.0348 0.036
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.0293 0.0284
Trichomonas vaginalis tubulin epsilon chain, putative 0.0526 0.3206 0.3931
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.037 0.0442
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0138 0.0918
Loa Loa (eye worm) tubulin alpha chain 0.0526 0.3206 0.3912
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Echinococcus granulosus chromobox protein 1 0.0072 0.0357 0.037
Schistosoma mansoni Smad4 0.0025 0.006 0.0053
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0526 0.3206 0.3931
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0081 0.041 0.0426
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0123 0.0678 0.0711
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0092 0.0481 0.0578
Brugia malayi hypothetical protein 0.0074 0.037 0.0442
Echinococcus granulosus tubulin gamma 1 chain 0.0457 0.2776 0.2945
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0026 0.0064 0.0066
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0138 0.1122
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0245 0.1445 0.1746
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0073 0.0077
Trypanosoma cruzi tubulin delta chain 0.0199 0.115 0.14
Brugia malayi MH2 domain containing protein 0.0056 0.0254 0.0299
Loa Loa (eye worm) hypothetical protein 0.0049 0.0213 0.0231
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0094 0.0104
Loa Loa (eye worm) hypothetical protein 0.0085 0.0436 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0158 0.0193
Brugia malayi hypothetical protein 0.0053 0.0236 0.0278
Echinococcus multilocularis Tubulin alpha 1 chain 0.0526 0.3206 0.3199
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0053 0.0236 0.0278
Echinococcus granulosus neuropeptide s receptor 0.0484 0.2945 0.3125
Echinococcus granulosus nuclear receptor nhr 48 0.0062 0.0293 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0143 0.0801 0.0971
Trypanosoma brucei zeta tubulin 0.0199 0.115 0.14
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0138 0.0169
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0073 0.0077
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0095
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0472 0.0568
Echinococcus multilocularis histone deacetylase 6 0.0527 0.3217 0.321
Echinococcus multilocularis Tubulin alpha 1 chain 0.0526 0.3206 0.3199
Loa Loa (eye worm) p25-alpha family protein 0.038 0.229 0.2786
Trypanosoma cruzi alpha tubulin, putative 0.0526 0.3206 0.3924
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0102 0.0113
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0138 0.0138
Schistosoma mansoni dihydrofolate reductase 0.0045 0.0189 0.019
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0143 0.0801 0.0842
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0094 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0094 0.0116
Echinococcus multilocularis geminin 0.1512 0.9403 0.9402
Onchocerca volvulus Protein ultraspiracle homolog 0.0143 0.0801 0.1668
Brugia malayi MH1 domain containing protein 0.0031 0.0097 0.0107
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0026 0.0019
Brugia malayi nuclear hormone receptor 0.0062 0.0293 0.0348
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0102 0.0092
Schistosoma mansoni cpg binding protein 0.0032 0.0101 0.0097
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0143 0.0801 0.0842
Echinococcus granulosus tubulin subunit beta 0.0756 0.4655 0.4946
Chlamydia trachomatis endonuclease IV 0.008 0.0403 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0308 0.184 0.1948
Schistosoma mansoni tubulin subunit beta 0.0756 0.4655 0.4946
Trichomonas vaginalis histone deacetylase, putative 0.1313 0.8154 1
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Loa Loa (eye worm) hypothetical protein 0.0117 0.0637 0.0752
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0138 0.0918
Loa Loa (eye worm) tubulin alpha-2 chain 0.0526 0.3206 0.3912
Trichomonas vaginalis esterase, putative 0.0037 0.0138 0.0169
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0612 0.0739
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0092 0.0481 0.0578
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0113 0.0611 0.064
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Onchocerca volvulus Histone deacetylase 10 homolog 0.041 0.2482 0.5329
Plasmodium vivax tubulin beta chain, putative 0.0756 0.4655 0.5704
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.1403 1
Brugia malayi nuclear receptor NHR-67 0.0062 0.0293 0.0348
Plasmodium vivax histone deacetylase, putative 0.0527 0.3217 0.3937
Echinococcus multilocularis tubulin alpha chain 0.0526 0.3206 0.3199
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0064 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0143 0.0801 0.0971
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0612 0.075
Schistosoma mansoni hypothetical protein 0.0321 0.192 0.2034
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Schistosoma mansoni smad 0.0056 0.0254 0.026
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0225 0.023
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0612 0.0739
Schistosoma mansoni alpha tubulin 0.0526 0.3206 0.3403
Trichomonas vaginalis tubulin, putative 0.0199 0.115 0.1411
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0138 0.1122
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0026 0.0019
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.037 0.0442
Loa Loa (eye worm) hypothetical protein 0.0047 0.0198 0.0213
Schistosoma mansoni chromobox protein 0.0072 0.0357 0.037
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0138 0.0169
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Mycobacterium tuberculosis Conserved protein 0.0037 0.0138 0.0918
Onchocerca volvulus 0.0112 0.0604 0.124
Trichomonas vaginalis tubulin epsilon chain, putative 0.0756 0.4655 0.5709
Echinococcus granulosus Tubulin alpha 1 chain 0.0526 0.3206 0.3403
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.0293 0.0284
Loa Loa (eye worm) BEN-1 protein 0.0756 0.4655 0.5695
Trichomonas vaginalis histone deacetylase, putative 0.1313 0.8154 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0457 0.2776 0.3404
Brugia malayi MH1 domain containing protein 0.0056 0.0254 0.0299
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0138 0.1122
Brugia malayi hypothetical protein 0.0321 0.192 0.2345
Brugia malayi follicle stimulating hormone receptor 0.0245 0.1445 0.1762
Loa Loa (eye worm) DR-78 0.0062 0.0293 0.0329
Echinococcus granulosus Tubulin beta 2C chain 0.0756 0.4655 0.4946
Trypanosoma brucei alpha tubulin 0.0526 0.3206 0.3924
Trichomonas vaginalis tubulin, putative 0.0756 0.4655 0.5709
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0094 0.0104
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0307 0.0317
Mycobacterium ulcerans beta-lactamase 0.0037 0.0138 0.1122
Echinococcus granulosus histone deacetylase 7 0.0527 0.3217 0.3414
Leishmania major trypanothione reductase 0.0049 0.0211 0.0247
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0612 0.0739
Echinococcus multilocularis lamin dm0 0.0028 0.0079 0.0069
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0131 0.0724 0.0715
Onchocerca volvulus 0.0051 0.0225 0.0416
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0143 0.0801 0.0842
Echinococcus granulosus TGF beta signal transducer SmadC 0.0056 0.0254 0.026
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.009 0.008
Loa Loa (eye worm) alpha-tubulin 0.0526 0.3206 0.3912
Onchocerca volvulus 0.0037 0.0138 0.0225
Mycobacterium ulcerans thymidylate synthase 0.0112 0.0604 0.5208
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0026 0.0064 0.0057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0065
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0026 0.0064 0.0066
Echinococcus multilocularis tubulin alpha 3 chain 0.0526 0.3206 0.3199
Loa Loa (eye worm) hypothetical protein 0.0155 0.0877 0.1048
Echinococcus granulosus Tubulin beta 2C chain 0.0756 0.4655 0.4946
Trypanosoma cruzi histone deacetylase, putative 0.0527 0.3217 0.3937
Echinococcus granulosus histone deacetylase 1 0.1313 0.8154 0.8671
Echinococcus granulosus single minded 2 0.0037 0.0138 0.0136
Echinococcus multilocularis thymidylate synthase 0.0112 0.0604 0.0595
Echinococcus multilocularis ecdysone induced protein 78C 0.0143 0.0801 0.0792
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0143 0.0801 0.0842
Trichomonas vaginalis histone deacetylase, putative 0.1313 0.8154 1
Echinococcus multilocularis transcription factor eb 0.0112 0.0607 0.0598
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0026 0.0019
Loa Loa (eye worm) hypothetical protein 0.0327 0.1958 0.2378
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1313 0.8154 1
Schistosoma mansoni tubulin subunit beta 0.0756 0.4655 0.4946
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0612 0.0721
Echinococcus multilocularis Tubulin alpha 1 chain 0.0526 0.3206 0.3199
Echinococcus multilocularis beta tubulin 0.0756 0.4655 0.465
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Giardia lamblia Gamma tubulin 0.0457 0.2776 0.3396
Echinococcus granulosus tubulin alpha chain 0.0526 0.3206 0.3403
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0143 0.0801 0.0792
Entamoeba histolytica tubulin family protein 0.0756 0.4655 0.5695
Giardia lamblia Beta tubulin 0.0756 0.4655 0.5704
Toxoplasma gondii histone deacetylase HDAC3 0.1313 0.8154 1
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0112 0.0604 0.4263
Echinococcus multilocularis tubulin epsilon chain 0.0457 0.2776 0.2769
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0324 0.0385
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0177 0.031
Echinococcus granulosus tubulin subunit TubB 0.0526 0.3206 0.3403
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0026 0.0019
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0357 0.0408
Echinococcus granulosus dihydrofolate reductase 0.0045 0.0189 0.019
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0606 0.4282
Mycobacterium tuberculosis Probable reductase 0.0112 0.0606 0.4282
Loa Loa (eye worm) nuclear receptor NHR-67 0.0062 0.0293 0.0329
Trichomonas vaginalis tubulin beta chain, putative 0.0526 0.3206 0.3931
Schistosoma mansoni tubulin subunit alpha 0.0526 0.3206 0.3403
Schistosoma mansoni Smad4 0.0025 0.006 0.0053
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Mycobacterium ulcerans lipase LipD 0.0037 0.0138 0.1122
Echinococcus granulosus intermediate filament protein 0.0028 0.0079 0.0073
Onchocerca volvulus TPPP family protein homolog 0.038 0.229 0.491
Plasmodium vivax histone deacetylase 2, putative 0.0527 0.3217 0.3937
Trypanosoma brucei beta tubulin 0.0756 0.4655 0.5704
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0267 0.158 0.1938
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0157 0.089 0.108
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.0481 0.0501
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0457 0.2776 0.3396
Echinococcus multilocularis histone deacetylase 1 0.1313 0.8154 0.8152
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0472 0.0493
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0612 0.0721
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0079 0.0065
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0083 0.0102
Brugia malayi Nuclear hormone receptor-like 1 0.0081 0.041 0.0492
Trichomonas vaginalis tubulin epsilon chain, putative 0.0526 0.3206 0.3931
Echinococcus multilocularis FTZ F1 alpha 0.0143 0.0801 0.0792
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0138 0.0128
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Echinococcus multilocularis BRCA1 associated protein 0.0026 0.0064 0.0054
Echinococcus multilocularis histone deacetylase 3 0.1313 0.8154 0.8152
Echinococcus granulosus mothers against decapentaplegic 6 0.0025 0.006 0.0053
Schistosoma mansoni alpha tubulin 0.0526 0.3206 0.3403
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.0293 0.0302
Echinococcus granulosus histone acetyltransferase KAT2B 0.0298 0.1774 0.1879
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0045 0.0189 0.1569
Plasmodium falciparum histone deacetylase 2 0.0527 0.3217 0.3937
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Brugia malayi alpha-tubulin 0.0526 0.3206 0.3924
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0472 0.055
Loa Loa (eye worm) CBP-B 0.0081 0.0409 0.0472
Brugia malayi tailless protein 0.0062 0.0293 0.0348
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0047 0.0198 0.0232
Mycobacterium ulcerans hypothetical protein 0.0037 0.0138 0.1122
Echinococcus granulosus Tubulin beta 2C chain 0.0756 0.4655 0.4946
Trypanosoma cruzi beta tubulin, putative 0.0756 0.4655 0.5704
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0052 0.0052
Schistosoma mansoni tubulin subunit beta 0.0756 0.4655 0.4946
Leishmania major zeta tubulin, putative 0.0199 0.115 0.14
Loa Loa (eye worm) hypothetical protein 0.0081 0.041 0.0473
Brugia malayi hypothetical protein 0.0081 0.041 0.0492
Echinococcus granulosus tubulin alpha chain 0.0526 0.3206 0.3403
Brugia malayi nuclear hormone receptor family member odr-7 0.0062 0.0293 0.0348
Echinococcus multilocularis CREB binding protein 0.0017 0.0011 0.0002
Echinococcus granulosus beta tubulin 0.0756 0.4655 0.4946
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0143 0.0801 0.0842
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0064 0.0078
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0123 0.0678 0.082
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0026 0.0064 0.0047
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0026 0.0019
Schistosoma mansoni retinoic acid receptor RXR 0.0245 0.1444 0.1527
Echinococcus multilocularis CREB binding protein 0.008 0.0403 0.0394
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Leishmania major gamma-tubulin 0.0457 0.2776 0.3396
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0606 0.4282
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.002 0.0024
Echinococcus multilocularis mothers against decapentaplegic 6 0.0025 0.006 0.005
Brugia malayi ecdysone receptor 0.0062 0.0293 0.0348
Giardia lamblia Histone deacetylase 0.1313 0.8154 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0052 0.0033
Schistosoma mansoni intermediate filament proteins 0.0028 0.0079 0.0073
Echinococcus multilocularis tubulin alpha 1C chain 0.0526 0.3206 0.3199
Schistosoma mansoni thyroid hormone receptor 0.0274 0.1622 0.1716
Brugia malayi Isocitrate dehydrogenase 0.0123 0.0678 0.082
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.001 0.0012
Mycobacterium ulcerans epimerase 0.0021 0.0034 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0138 0.0157
Trypanosoma brucei alpha tubulin 0.0526 0.3206 0.3924
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0199 0.115 0.14
Brugia malayi steroid hormone receptor 0.0143 0.0801 0.0971
Brugia malayi MH1 domain containing protein 0.0031 0.0097 0.0107
Entamoeba histolytica hypothetical protein 0.0321 0.192 0.233
Schistosoma mansoni histone deacetylase 4 5 0.0527 0.3217 0.3414
Loa Loa (eye worm) hypothetical protein 0.0081 0.041 0.0473
Echinococcus granulosus neuropeptide receptor A26 0.0484 0.2945 0.3125
Toxoplasma gondii beta tubulin 0.0756 0.4655 0.5704
Echinococcus multilocularis tubulin alpha 0.0457 0.2776 0.2769
Trypanosoma brucei beta tubulin 0.0756 0.4655 0.5704
Giardia lamblia Delta tubulin 0.0199 0.115 0.14
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0052 0.0052
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0047 0.0198 0.0213
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0225 0.0246
Brugia malayi beta-tubulin, identical 0.0756 0.4655 0.5704
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Echinococcus granulosus mothers against decapentaplegic 5 0.0056 0.0254 0.026
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.006 0.0042
Trypanosoma brucei alpha tubulin 0.0526 0.3206 0.3924
Plasmodium vivax histone deacetylase, putative 0.041 0.2482 0.3036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0026 0.0019
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0158 0.0193
Schistosoma mansoni tubulin subunit beta 0.0756 0.4655 0.4946
Echinococcus granulosus chromobox protein 1 0.0072 0.0357 0.037
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0026 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0472 0.0493
Toxoplasma gondii beta-tubulin, putative 0.0756 0.4655 0.5704
Schistosoma mansoni chromobox protein 0.0072 0.0357 0.037
Toxoplasma gondii isocitrate dehydrogenase 0.0123 0.0678 0.082
Brugia malayi tubulin alpha chain - mouse 0.0526 0.3206 0.3924
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0034 0.0216
Brugia malayi glutathione reductase 0.0049 0.0211 0.0247
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0052 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Mycobacterium leprae cell division protein FtsZ 0.0199 0.115 1
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0612 0.0721
Plasmodium vivax delta tubulin, putative 0.0199 0.115 0.14
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0102 0.0098
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0064 0.0066
Toxoplasma gondii isocitrate dehydrogenase 0.0123 0.0678 0.082
Loa Loa (eye worm) tubulin beta-4 chain 0.0756 0.4655 0.5695
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0026 0.0064 0.0054
Brugia malayi Pre-SET motif family protein 0.0032 0.0102 0.0113
Brugia malayi Cytochrome P450 family protein 0.0024 0.0052 0.0052
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0612 0.075
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0403 0.2821
Brugia malayi Tubulin beta-1 chain 0.0756 0.4655 0.5704
Echinococcus multilocularis smad 0.0056 0.0254 0.0244
Loa Loa (eye worm) thymidylate synthase 0.0112 0.0604 0.0711
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0327 0.1958 0.2378
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0026 0.0064 0.0066
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0612 0.4321
Echinococcus granulosus Tubulin beta 2C chain 0.0756 0.4655 0.4946
Loa Loa (eye worm) tubulin beta-1 chain 0.0756 0.4655 0.5695
Brugia malayi hypothetical protein 0.0048 0.0204 0.0239
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0143 0.0801 0.0953
Brugia malayi Nuclear hormone receptor E75 0.0062 0.0293 0.0348
Echinococcus granulosus tubulin alpha chain 0.0526 0.3206 0.3403
Brugia malayi isocitrate dehydrogenase 0.0123 0.0678 0.082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0102 0.0098
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0094 0.0104
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0073 0.0077
Schistosoma mansoni cpg binding protein 0.003 0.009 0.0086
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0062 0.0293 0.0284
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0079 0.0065
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0357 0.0438
Trichomonas vaginalis tubulin alpha chain, putative 0.0756 0.4655 0.5709
Giardia lamblia Beta tubulin 0.0756 0.4655 0.5704
Leishmania major hypothetical protein, conserved 0.0074 0.037 0.0442
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0073 0.0058
Schistosoma mansoni hypothetical protein 0.0032 0.0105 0.0101
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0612 0.0641
Schistosoma mansoni brca1-associated protein (brap2) 0.0026 0.0064 0.0057
Loa Loa (eye worm) hypothetical protein 0.0032 0.0102 0.0094
Brugia malayi nuclear receptor NHR-88 0.0143 0.0801 0.0971
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0138 0.0169
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0612 0.528
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0143 0.0801 0.0953
Loa Loa (eye worm) beta-lactamase 0.0037 0.0138 0.0138
Plasmodium falciparum alpha tubulin 2 0.0526 0.3206 0.3924
Trypanosoma brucei histone deacetylase 2 0.041 0.2482 0.3036
Brugia malayi p25-alpha family protein 0.038 0.229 0.28
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0143 0.0801 0.0971
Brugia malayi hypothetical protein 0.0081 0.041 0.0492
Plasmodium falciparum histone deacetylase, putative 0.0527 0.3217 0.3937
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0158 0.0268
Echinococcus multilocularis histone deacetylase 6 0.0527 0.3217 0.321
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0143 0.0801 0.0792
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0123 0.0678 0.082
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0026 0.0064 0.0066
Brugia malayi hypothetical protein 0.0068 0.0333 0.0397
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Loa Loa (eye worm) histone deacetylase 7A 0.0527 0.3217 0.3926
Schistosoma mansoni brca1-associated protein (brap2) 0.0026 0.0064 0.0057
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0064 0.0066
Echinococcus granulosus ecdysone induced protein 78C 0.0143 0.0801 0.0842
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0143 0.0801 0.0971
Echinococcus multilocularis tubulin beta 1 chain 0.0756 0.4655 0.465
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0606 0.5127
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0472 0.0463
Echinococcus multilocularis Tubulin beta 2C chain 0.0756 0.4655 0.465
Loa Loa (eye worm) hypothetical protein 0.0526 0.3206 0.3912
Trichomonas vaginalis tubulin beta chain, putative 0.0259 0.1528 0.1874
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0026 0.0064 0.0057
Schistosoma mansoni histone deacetylase hda2 0.0553 0.3377 0.3585
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0138 0.0918
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0138 0.0918
Echinococcus multilocularis CREB binding protein 0.0017 0.0011 0.0002
Echinococcus multilocularis tumor protein p63 0.0351 0.2107 0.2099
Echinococcus granulosus alpha tubulin 0.0526 0.3206 0.3403
Echinococcus granulosus CREB binding protein 0.0113 0.0611 0.064
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0034 0.0177
Brugia malayi nuclear hormone receptor family member nhr-6 0.0062 0.0293 0.0348
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0052 0.0052
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0138 0.0157
Loa Loa (eye worm) hypothetical protein 0.0041 0.0158 0.0162
Echinococcus granulosus tubulin alpha chain 0.0526 0.3206 0.3403
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0081 0.041 0.0473
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0143 0.0801 0.0953
Schistosoma mansoni ap endonuclease 0.002 0.0026 0.0017
Brugia malayi Steroid receptor seven-up type 2 0.0143 0.0801 0.0971
Brugia malayi Nuclear hormone receptor-like 1 0.0143 0.0801 0.0971
Brugia malayi 6-phosphofructokinase 0.0113 0.0612 0.0739
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0026 0.0031
Echinococcus multilocularis mothers against decapentaplegic 2 0.0025 0.006 0.005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0102 0.0092
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0138 0.0918
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0138 0.0918
Trichomonas vaginalis tubulin beta chain, putative 0.0756 0.4655 0.5709
Loa Loa (eye worm) pax transcription factor protein 2 0.0752 0.4628 0.5662
Trichomonas vaginalis histone deacetylase, putative 0.1313 0.8154 1
Plasmodium falciparum tubulin delta chain, putative 0.0199 0.115 0.14
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0403 0.0483
Plasmodium vivax histone deacetylase 1, putative 0.1313 0.8154 1
Toxoplasma gondii thioredoxin reductase 0.0049 0.0211 0.0247
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0143 0.0801 0.0842
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0157 0.089 0.108
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0094 0.0116
Onchocerca volvulus Bile acid receptor homolog 0.0143 0.0801 0.1668
Echinococcus granulosus tubulin alpha 1C chain 0.0526 0.3206 0.3403
Echinococcus multilocularis mothers against decapentaplegic 5 0.0056 0.0254 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0199 0.115 0.1411
Entamoeba histolytica tubulin gamma chain 0.0457 0.2776 0.3383
Echinococcus granulosus FTZ F1 alpha 0.0143 0.0801 0.0842
Loa Loa (eye worm) acetyltransferase 0.0308 0.184 0.2232
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0143 0.0801 0.0953
Giardia lamblia Epsilon tubulin 0.0199 0.115 0.14
Schistosoma mansoni alpha tubulin 0.0526 0.3206 0.3403
Echinococcus multilocularis muscleblind protein 0.0155 0.0877 0.0868
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.037 0.0442
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0026 0.0064 0.0057
Brugia malayi hypothetical protein 0.0062 0.0293 0.0348
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0211 0.0247
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0026 0.0064 0.0047
Onchocerca volvulus 0.0037 0.0138 0.0225
Schistosoma mansoni nuclear hormone receptor 0.0143 0.0801 0.0842
Echinococcus granulosus Tubulin alpha 1 chain 0.0526 0.3206 0.3403
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0026 0.0064 0.0047
Echinococcus multilocularis dihydrofolate reductase 0.0045 0.0189 0.0179
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.0451 0.0469
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0094 0.0104
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0606 0.4282
Onchocerca volvulus 0.0038 0.0141 0.0232
Trypanosoma brucei beta tubulin 0.0457 0.2776 0.3396
Trichomonas vaginalis tubulin, putative 0.0259 0.1528 0.1874
Echinococcus granulosus thymidylate synthase 0.0112 0.0604 0.0632
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0034 0.003
Schistosoma mansoni lamin 0.0028 0.0079 0.0073
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Schistosoma mansoni smad 0.0025 0.006 0.0053
Loa Loa (eye worm) tubulin beta chain 0.0199 0.115 0.1384
Schistosoma mansoni zinc finger protein 0.0062 0.0293 0.0302
Leishmania major hypothetical protein, conserved 0.0037 0.0138 0.0157
Echinococcus granulosus transcription factor eb 0.0112 0.0607 0.0636
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0138 0.0157
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0199 0.115 0.14
Echinococcus granulosus thyroid hormone receptor alpha 0.0062 0.0293 0.0302
Echinococcus granulosus geminin 0.1512 0.9403 1
Loa Loa (eye worm) beta-tubulin 0.0756 0.4655 0.5695
Schistosoma mansoni coup transcription factor 0.0143 0.0801 0.0842
Echinococcus multilocularis Tubulin beta 2C chain 0.0756 0.4655 0.465
Trypanosoma cruzi histone deacetylase, putative 0.0527 0.3217 0.3937
Brugia malayi Nuclear hormone receptor E75 0.0062 0.0293 0.0348
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0245 0.1444 0.1527
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0308 0.184 0.1832
Echinococcus multilocularis muscleblind protein 1 0.0155 0.0877 0.0868
Brugia malayi beta-lactamase 0.0037 0.0138 0.0157
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Schistosoma mansoni steroid hormone receptor ad4bp 0.0143 0.0801 0.0842
Trichomonas vaginalis tubulin gamma chain, putative 0.0756 0.4655 0.5709
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0143 0.0801 0.0971
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0056 0.0254 0.0244
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Plasmodium vivax tubulin alpha chain, putative 0.0526 0.3206 0.3924
Loa Loa (eye worm) histone deacetylase 11 0.041 0.2482 0.3022
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0123 0.0678 0.0669
Brugia malayi acetyltransferase, GNAT family protein 0.0308 0.184 0.2247
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0094 0.2154
Brugia malayi bZIP transcription factor family protein 0.0087 0.0451 0.0541
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0026 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0026 0.0064 0.0066
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0112 0.0607 0.0733
Brugia malayi BRCA1-associated protein 2 containing protein 0.0026 0.0064 0.0066
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0612 0.0641
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0094 0.0085
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1313 0.8154 1
Trypanosoma cruzi histone deacetylase, putative 0.0527 0.3217 0.3937
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0026 0.0064 0.0047
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0211 0.0215
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0123 0.0678 0.082
Echinococcus multilocularis tubulin subunit TubB 0.0526 0.3206 0.3199
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0073 0.0058
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0062 0.0293 0.0348
Plasmodium falciparum tubulin epsilon chain, putative 0.0457 0.2776 0.3396
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0064 0.0066
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0026 0.0064 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0143 0.0801 0.0953
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0143 0.0801 0.0842
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0064 0.0066
Plasmodium falciparum histone deacetylase 1 0.1313 0.8154 1
Toxoplasma gondii exonuclease III APE 0.002 0.0026 0.0019
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0026 0.0016
Brugia malayi Tubulin alpha-2 chain 0.0526 0.3206 0.3924
Onchocerca volvulus 0.0032 0.0103 0.0149
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0094 0.0742
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0064 0.0078
Onchocerca volvulus 0.003 0.009 0.0122
Trypanosoma brucei histone deacetylase 3 0.0527 0.3217 0.3937
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0138 0.0926
Trichomonas vaginalis tubulin beta chain, putative 0.0526 0.3206 0.3931
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0079 0.0085
Brugia malayi PAS domain containing protein 0.0051 0.022 0.0258
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0026 0.0064 0.0066
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0143 0.0801 0.0842
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.009 0.0086
Onchocerca volvulus 0.0062 0.0293 0.0564
Echinococcus multilocularis histone deacetylase 6 0.0553 0.3377 0.3371
Echinococcus granulosus tubulin alpha 1C chain 0.0526 0.3206 0.3403
Echinococcus granulosus CREB binding protein 0.0017 0.0011 0.0002
Onchocerca volvulus 0.0062 0.0293 0.0564
Brugia malayi Cytochrome P450 family protein 0.0054 0.0244 0.0288
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0177 0.0217
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0062 0.0293 0.0302
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0612 0.0721
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0123 0.0678 0.082
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0169 0.0967 0.1159
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0612 0.0641
Plasmodium falciparum tubulin gamma chain 0.0457 0.2776 0.3396
Mycobacterium ulcerans cell division protein FtsZ 0.0199 0.115 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.0877 0.1048
Onchocerca volvulus 0.0028 0.0079 0.0097
Echinococcus multilocularis Tubulin beta 2C chain 0.0756 0.4655 0.465
Chlamydia trachomatis dihydrofolate reductase 0.0045 0.0189 0.4552
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0244 0.0269
Loa Loa (eye worm) hypothetical protein 0.0037 0.0138 0.0138
Schistosoma mansoni histone deacetylase 0.1313 0.8154 0.8671
Leishmania major beta tubulin 0.0756 0.4655 0.5704
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0143 0.0801 0.0971
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0026 0.0019
Schistosoma mansoni hypothetical protein 0.0131 0.0724 0.0761
Loa Loa (eye worm) nuclear factor I 0.0031 0.0097 0.0088
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0062 0.0293 0.0302
Onchocerca volvulus 0.0028 0.0079 0.0097
Echinococcus granulosus tubulin beta 1 chain 0.0756 0.4655 0.4946
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0138 0.0157
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0321 0.192 0.2034
Trichomonas vaginalis brca1-associated protein, putative 0.0026 0.0064 0.0078
Echinococcus granulosus histone deacetylase 6 0.0527 0.3217 0.3414
Echinococcus multilocularis peroxisome assembly protein 26 0.0526 0.3206 0.3199
Trypanosoma cruzi histone deacetylase 1, putative 0.1313 0.8154 1
Mycobacterium leprae Probable lipase LipE 0.0037 0.0138 0.0926
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0062
Echinococcus multilocularis tubulin alpha chain 0.0526 0.3206 0.3199
Loa Loa (eye worm) MH1 domain-containing protein 0.0056 0.0254 0.0281
Loa Loa (eye worm) hypothetical protein 0.0143 0.0801 0.0953
Schistosoma mansoni histone deacetylase 0.1313 0.8154 0.8671
Brugia malayi mothers against decapentaplegic homolog 3 0.0025 0.006 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0472 0.0493
Leishmania major histone deacetylase, putative 0.1313 0.8154 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0081 0.041 0.0426
Trypanosoma brucei alpha tubulin, putative 0.0259 0.1528 0.1865
Echinococcus granulosus Smad4 0.0056 0.0254 0.026
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0094 0.0116
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0211 0.0202
Brugia malayi CXXC zinc finger family protein 0.003 0.009 0.0099
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0143 0.0801 0.0971
Leishmania major histone deacetylase, putative 0.0527 0.3217 0.3937
Trichomonas vaginalis tubulin gamma chain, putative 0.0457 0.2776 0.3404
Echinococcus granulosus CREB binding protein 0.0017 0.0011 0.0002
Loa Loa (eye worm) hypothetical protein 0.0142 0.0798 0.095
Trichomonas vaginalis tubulin alpha chain, putative 0.0259 0.1528 0.1874
Trypanosoma cruzi histone deacetylase 1, putative 0.1313 0.8154 1
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Onchocerca volvulus 0.0752 0.4628 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0819 0.505 0.6182
Brugia malayi nuclear receptor NHR-88 0.0062 0.0293 0.0348
Toxoplasma gondii histone deacetylase HDAC5 0.041 0.2482 0.3036
Leishmania major alpha tubulin 0.0526 0.3206 0.3924
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0124 0.0685 0.583
Entamoeba histolytica tubulin family protein 0.0756 0.4655 0.5695
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0259 0.1528 0.1874
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0612 0.075
Loa Loa (eye worm) hypothetical protein 0.0062 0.0293 0.0329
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0094 0.0116
Trichomonas vaginalis tubulin, putative 0.0259 0.1528 0.1874
Loa Loa (eye worm) Smad1 0.0056 0.0254 0.0281
Echinococcus multilocularis tubulin subunit beta 0.0756 0.4655 0.465
Trypanosoma brucei beta tubulin 0.0756 0.4655 0.5704
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0026 0.0064 0.0064
Schistosoma mansoni tubulin subunit epsilon 0.0457 0.2776 0.2945
Onchocerca volvulus 0.0037 0.0138 0.0225
Brugia malayi photoreceptor-specific nuclear receptor 0.0143 0.0801 0.0971
Loa Loa (eye worm) hypothetical protein 0.0037 0.0138 0.0138
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0026 0.0064 0.0057
Schistosoma mansoni nuclear receptor 0.0062 0.0293 0.0302
Onchocerca volvulus 0.0259 0.1528 0.3252
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0138 0.0136
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0123 0.0678 0.082
Trypanosoma cruzi histone deacetylase, putative 0.041 0.2482 0.3036
Loa Loa (eye worm) transcription factor SMAD2 0.0819 0.505 0.6182
Brugia malayi Nuclear hormone receptor-like 1 0.0081 0.041 0.0492
Schistosoma mansoni hypothetical protein 0.0111 0.0603 0.0632
Schistosoma mansoni tubulin subunit alpha 0.0526 0.3206 0.3403
Loa Loa (eye worm) hypothetical protein 0.0037 0.0138 0.0138
Echinococcus granulosus Tubulin alpha 1 chain 0.0526 0.3206 0.3403
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0143 0.0801 0.0792

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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