Detailed information for compound 788945

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 412.502 | Formula: C22H24N2O4S
  • H donors: 1 H acceptors: 2 LogP: 3.25 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCCNC(=O)Cn1c(=O)c(=Cc2ccc(cc2)OC)sc2c1cccc2
  • InChi: 1S/C22H24N2O4S/c1-27-13-5-12-23-21(25)15-24-18-6-3-4-7-19(18)29-20(22(24)26)14-16-8-10-17(28-2)11-9-16/h3-4,6-11,14H,5,12-13,15H2,1-2H3,(H,23,25)/b20-14-
  • InChiKey: VERQFCFIQYKLPW-ZHZULCJRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax histone deacetylase 1, putative 0.1367 0.8154 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0149 0.0801 0.0943
Plasmodium falciparum thioredoxin reductase 0.0051 0.0211 0.0247
Trichomonas vaginalis tubulin beta chain, putative 0.0536 0.3141 0.3852
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0022 0.0038 0.0008
Toxoplasma gondii alpha-tubulin I, putative 0.0536 0.3141 0.3845
Trypanosoma cruzi histone deacetylase, putative 0.0549 0.3217 0.3937
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0073 0.0077
Loa Loa (eye worm) hypothetical protein 0.0039 0.0138 0.0138
Loa Loa (eye worm) histone deacetylase 3 0.1367 0.8154 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1367 0.8154 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0798 0.095
Onchocerca volvulus 0.0263 0.1492 0.3172
Echinococcus multilocularis histone deacetylase 8 0.0427 0.2482 0.2475
Brugia malayi hypothetical protein 0.0053 0.022 0.0258
Brugia malayi Pax transcription factor protein 2 0.0783 0.4628 0.5671
Loa Loa (eye worm) transcription factor SMAD2 0.0735 0.4343 0.5311
Schistosoma mansoni alpha tubulin 0.0536 0.3141 0.3733
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0079 0.0085
Schistosoma mansoni Smad4 0.005 0.0205 0.0233
Trichomonas vaginalis tubulin alpha chain, putative 0.0263 0.1492 0.1829
Echinococcus multilocularis smad 0.005 0.0205 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0083 0.0102
Trichomonas vaginalis histone deacetylase, putative 0.1367 0.8154 1
Chlamydia trachomatis endonuclease IV 0.0083 0.0403 1
Echinococcus granulosus jun protein 0.0091 0.0451 0.0526
Trypanosoma cruzi histone deacetylase, putative 0.0549 0.3217 0.3937
Trypanosoma brucei beta tubulin 0.0465 0.2711 0.3317
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.0029 0.0079 0.0065
Trichomonas vaginalis tubulin, putative 0.0263 0.1492 0.1829
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.0606 0.526
Echinococcus multilocularis nuclear receptor nhr 48 0.0065 0.0293 0.0284
Trypanosoma brucei alpha tubulin, putative 0.0263 0.1492 0.182
Leishmania major trypanothione reductase 0.0051 0.0211 0.0247
Brugia malayi beta-tubulin, identical 0.0759 0.4488 0.5499
Loa Loa (eye worm) tubulin beta-4 chain 0.0759 0.4488 0.549
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.013 0.0685 0.4845
Echinococcus multilocularis Tubulin alpha 1 chain 0.0536 0.3141 0.3134
Loa Loa (eye worm) CBP-B 0.0084 0.0409 0.0472
Onchocerca volvulus 0.0783 0.4628 1
Onchocerca volvulus Histone deacetylase 10 homolog 0.0427 0.2482 0.5329
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0138 0.0918
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0612 0.075
Trichomonas vaginalis tubulin, putative 0.0263 0.1492 0.1829
Brugia malayi nuclear hormone receptor 0.0149 0.0801 0.0971
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0138 0.0153
Echinococcus granulosus Tubulin alpha 1 chain 0.0536 0.3141 0.3733
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0536 0.3141 0.3852
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0113 0.0584 0.0705
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0149 0.0801 0.0953
Echinococcus granulosus single minded 2 0.0039 0.0138 0.0153
Loa Loa (eye worm) tubulin gamma chain 0.0465 0.2711 0.3304
Onchocerca volvulus 0.0039 0.0138 0.0225
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0027 0.0064 0.0066
Echinococcus multilocularis tubulin beta 1 chain 0.0759 0.4488 0.4483
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0293 0.0284
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0027 0.0064 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0149 0.0801 0.0971
Brugia malayi Cytochrome P450 family protein 0.0025 0.0052 0.0052
Echinococcus multilocularis BRCA1 associated protein 0.0027 0.0064 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0236 0.029
Schistosoma mansoni tubulin subunit epsilon 0.0465 0.2711 0.322
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0027 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.1367 0.8154 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0064 0.0078
Echinococcus multilocularis ecdysone induced protein 78C 0.0149 0.0801 0.0792
Echinococcus granulosus smad 0.005 0.0205 0.0233
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0027 0.0064 0.0066
Schistosoma mansoni histone deacetylase 4 5 0.0549 0.3217 0.3823
Brugia malayi histone deacetylase 3 (HD3) 0.1367 0.8154 1
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0612 0.0739
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0149 0.0801 0.0943
Brugia malayi MH2 domain containing protein 0.005 0.0205 0.024
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0027 0.0064 0.0066
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0064 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0094 0.0116
Trichomonas vaginalis tubulin beta chain, putative 0.0536 0.3141 0.3852
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0094 0.0104
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.002 0.0024
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0026 0.0019
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0073 0.0077
Echinococcus multilocularis peroxisome assembly protein 26 0.0536 0.3141 0.3134
Trypanosoma brucei histone deacetylase, putative 0.0549 0.3217 0.3937
Onchocerca volvulus 0.0039 0.0138 0.0225
Schistosoma mansoni intermediate filament proteins 0.0029 0.0079 0.0082
Loa Loa (eye worm) hypothetical protein 0.0176 0.0967 0.1159
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0612 0.0718
Schistosoma mansoni flap endonuclease-1 0.0025 0.0056 0.0056
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0612 0.0721
Schistosoma mansoni zinc finger protein 0.0065 0.0293 0.0338
Trichomonas vaginalis tubulin, putative 0.0202 0.1122 0.1376
Loa Loa (eye worm) hypothetical protein 0.0161 0.0877 0.1048
Trichomonas vaginalis tubulin gamma chain, putative 0.0465 0.2711 0.3325
Brugia malayi thymidylate synthase 0.0116 0.0604 0.0729
Brugia malayi orphan nuclear receptor NR2E1 0.0065 0.0293 0.0348
Echinococcus granulosus histone deacetylase 6 0.0576 0.3377 0.4015
Toxoplasma gondii alpha tubulin TUBA1 0.0536 0.3141 0.3845
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0094 0.0116
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Plasmodium falciparum alpha tubulin 1 0.0536 0.3141 0.3845
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0158 0.0193
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0205 0.0196
Brugia malayi nuclear receptor NHR-67 0.0065 0.0293 0.0348
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0094 0.0104
Echinococcus granulosus thyroid hormone receptor alpha 0.0065 0.0293 0.0338
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0149 0.0801 0.0971
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0136 0.0724 0.0715
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0064 0.0078
Schistosoma mansoni hypothetical protein 0.0299 0.1706 0.2023
Trichomonas vaginalis tubulin epsilon chain, putative 0.0759 0.4488 0.5504
Loa Loa (eye worm) hypothetical protein 0.0039 0.0138 0.0138
Echinococcus granulosus flap endonuclease 1 0.0028 0.0073 0.0075
Toxoplasma gondii histone deacetylase HDAC2 0.1367 0.8154 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0138 0.0918
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0205 0.0233
Echinococcus granulosus dihydrofolate reductase 0.0047 0.0189 0.0213
Trichomonas vaginalis tubulin epsilon chain, putative 0.0759 0.4488 0.5504
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0073 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0149 0.0801 0.0971
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0759 0.4488 0.4483
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0026 0.0019
Echinococcus multilocularis lamin 0.0029 0.0079 0.0069
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0149 0.0801 0.0943
Trypanosoma cruzi epsilon tubulin, putative 0.0465 0.2711 0.3317
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0138 0.0128
Toxoplasma gondii isocitrate dehydrogenase 0.0113 0.0584 0.0705
Trichomonas vaginalis tubulin alpha chain, putative 0.0263 0.1492 0.1829
Toxoplasma gondii isocitrate dehydrogenase 0.0113 0.0584 0.0705
Toxoplasma gondii beta-tubulin, putative 0.0759 0.4488 0.5499
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0149 0.0801 0.0971
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0113 0.0584 0.0685
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0138 0.0169
Schistosoma mansoni nuclear receptor 0.0065 0.0293 0.0338
Echinococcus granulosus tubulin delta chain 0.0202 0.1122 0.1326
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0015
Echinococcus multilocularis geminin 0.1407 0.8398 0.8396
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0293 0.0338
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0202 0.1122 1
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0138 0.0918
Loa Loa (eye worm) phosphofructokinase 0.0117 0.0612 0.0721
Toxoplasma gondii histone deacetylase HDAC5 0.0427 0.2482 0.3036
Echinococcus multilocularis Tubulin alpha 1 chain 0.0536 0.3141 0.3134
Loa Loa (eye worm) hypothetical protein 0.0084 0.041 0.0473
Entamoeba histolytica hypothetical protein 0.0299 0.1706 0.2068
Onchocerca volvulus 0.0031 0.009 0.0122
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0255 0.1444 0.1709
Schistosoma mansoni histone deacetylase 4 5 0.0549 0.3217 0.3823
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Brugia malayi hypothetical protein 0.0055 0.0236 0.0278
Plasmodium vivax tubulin alpha chain, putative 0.0536 0.3141 0.3845
Entamoeba histolytica tubulin family protein 0.0759 0.4488 0.549
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Brugia malayi photoreceptor-specific nuclear receptor 0.0149 0.0801 0.0971
Onchocerca volvulus 0.0053 0.0225 0.0416
Loa Loa (eye worm) hypothetical protein 0.0039 0.0138 0.0138
Trichomonas vaginalis tubulin alpha chain, putative 0.0759 0.4488 0.5504
Brugia malayi Muscleblind-like protein 0.0161 0.0877 0.1065
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0299 0.1706 0.2023
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0094 0.0116
Onchocerca volvulus 0.0116 0.0604 0.124
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0052 0.0052
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0065 0.0293 0.0338
Leishmania major hypothetical protein, conserved 0.0027 0.0064 0.0066
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0027 0.0064 0.0066
Brugia malayi isocitrate dehydrogenase 0.0113 0.0584 0.0705
Echinococcus granulosus tubulin alpha 1C chain 0.0536 0.3141 0.3733
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Brugia malayi 6-phosphofructokinase 0.0117 0.0612 0.0739
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0138 0.0169
Brugia malayi Cytochrome P450 family protein 0.0057 0.0244 0.0288
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0034 0.0221
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0026 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0138 0.0169
Echinococcus multilocularis histone deacetylase 6 0.0576 0.3377 0.3371
Echinococcus granulosus tumor protein p63 0.0365 0.2107 0.25
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0138 0.0153
Brugia malayi MH2 domain containing protein 0.0735 0.4343 0.532
Leishmania major hypothetical protein, conserved 0.0039 0.0138 0.0157
Echinococcus multilocularis beta tubulin 0.0759 0.4488 0.4483
Toxoplasma gondii ABC1 family protein 0.0039 0.0138 0.0157
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0094 0.0104
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0026 0.0016
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0038 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.1367 0.8154 1
Trypanosoma brucei zeta tubulin 0.0202 0.1122 0.1366
Echinococcus multilocularis tubulin alpha 3 chain 0.0536 0.3141 0.3134
Brugia malayi beta-lactamase 0.0039 0.0138 0.0157
Brugia malayi nuclear receptor NHR-88 0.0149 0.0801 0.0971
Echinococcus multilocularis transcription factor eb 0.0117 0.0607 0.0598
Schistosoma mansoni ap endonuclease 0.002 0.0026 0.0019
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.0084 0.041 0.0473
Echinococcus granulosus FTZ F1 alpha 0.0149 0.0801 0.0943
Leishmania major zeta tubulin, putative 0.0202 0.1122 0.1366
Echinococcus multilocularis tubulin gamma 1 chain 0.0465 0.2711 0.2704
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0211 0.1446
Echinococcus granulosus peroxisome assembly protein 26 0.0536 0.3141 0.3733
Schistosoma mansoni steroid hormone receptor ad4bp 0.0149 0.0801 0.0943
Onchocerca volvulus 0.0029 0.0079 0.0097
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0202 0.1122 0.1366
Brugia malayi Steroid receptor seven-up type 2 0.0149 0.0801 0.0971
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0299 0.1706 0.1698
Schistosoma mansoni coup transcription factor 0.0149 0.0801 0.0943
Echinococcus granulosus chromobox protein 1 0.0075 0.0357 0.0414
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0163 0.089 0.108
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0149 0.0801 0.0971
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0201 0.0228
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1367 0.8154 1
Brugia malayi hypothetical protein 0.0084 0.041 0.0492
Onchocerca volvulus 0.0045 0.0176 0.0308
Loa Loa (eye worm) alpha-tubulin 0.0536 0.3141 0.3833
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0064 0.0078
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Echinococcus granulosus Tubulin beta 2C chain 0.0759 0.4488 0.5339
Loa Loa (eye worm) hypothetical protein 0.0029 0.0076 0.0062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0201 0.0228
Leishmania major hypothetical protein, conserved 0.0053 0.022 0.0258
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0052 0.0383
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0293 0.0338
Loa Loa (eye worm) hypothetical protein 0.0161 0.0877 0.1048
Entamoeba histolytica tubulin alpha chain, putative 0.0536 0.3141 0.3833
Mycobacterium leprae Probable lipase LipE 0.0039 0.0138 0.095
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0027 0.0064 0.0047
Plasmodium falciparum flap endonuclease 1 0.0028 0.0073 0.0077
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0065 0.0293 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0149 0.0801 0.0971
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0293 0.0338
Brugia malayi Pre-SET motif family protein 0.0033 0.0102 0.0113
Schistosoma mansoni brca1-associated protein (brap2) 0.0027 0.0064 0.0064
Onchocerca volvulus 0.0071 0.0333 0.065
Echinococcus multilocularis Tubulin beta 2C chain 0.0759 0.4488 0.4483
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Plasmodium vivax tubulin beta chain, putative 0.0759 0.4488 0.5499
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0027 0.0064 0.0054
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0094 0.0116
Mycobacterium tuberculosis Probable reductase 0.0117 0.0606 0.4282
Echinococcus granulosus cpg binding protein 0.0033 0.0101 0.0109
Trypanosoma brucei alpha tubulin 0.0536 0.3141 0.3845
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.022 0.0258
Echinococcus granulosus intermediate filament protein 0.0029 0.0079 0.0082
Trypanosoma cruzi histone deacetylase, putative 0.0427 0.2482 0.3036
Brugia malayi Tubulin alpha-2 chain 0.0536 0.3141 0.3845
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0612 0.0739
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0149 0.0801 0.0792
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0138 0.0157
Echinococcus multilocularis histone deacetylase 6 0.0549 0.3217 0.321
Brugia malayi Histone deacetylase family protein 0.0549 0.3217 0.3937
Loa Loa (eye worm) hypothetical protein 0.0039 0.0138 0.0138
Loa Loa (eye worm) steroid hormone receptor 0.0149 0.0801 0.0953
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0403 0.0483
Brugia malayi p25-alpha family protein 0.0395 0.229 0.28
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0149 0.0801 0.0792
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0094 0.0116
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0027 0.0064 0.0066
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0116 0.0604 0.0708
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0102 0.011
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0293 0.0348
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0027 0.0064 0.0047
Leishmania major histone deacetylase, putative 0.0549 0.3217 0.3937
Echinococcus multilocularis tubulin alpha 1C chain 0.0536 0.3141 0.3134
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0027 0.0064 0.0047
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.0612 0.4321
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0149 0.0801 0.0971
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0027 0.0064 0.0066
Trichomonas vaginalis tubulin beta chain, putative 0.0263 0.1492 0.1829
Echinococcus granulosus ecdysone induced protein 78C 0.0149 0.0801 0.0943
Giardia lamblia Hypothetical protein 0.0027 0.0064 0.0066
Trypanosoma brucei beta tubulin 0.0759 0.4488 0.5499
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0113 0.0584 0.0705
Brugia malayi bZIP transcription factor family protein 0.0091 0.0451 0.0541
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0149 0.0801 0.0953
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0094 0.2154
Loa Loa (eye worm) acetyltransferase 0.0321 0.184 0.2232
Toxoplasma gondii histone deacetylase HDAC1 0.0549 0.3217 0.3937
Echinococcus multilocularis CREB binding protein 0.0083 0.0403 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0149 0.0801 0.0971
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0138 0.0169
Mycobacterium tuberculosis Cell division protein FtsZ 0.0202 0.1122 0.7982
Trichomonas vaginalis tubulin beta chain, putative 0.0536 0.3141 0.3852
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0026 0.0019
Echinococcus granulosus tubulin gamma 1 chain 0.0465 0.2711 0.322
Leishmania major delta tubulin, putative 0.0202 0.1122 0.1366
Echinococcus granulosus Tubulin beta 2C chain 0.0759 0.4488 0.5339
Giardia lamblia Beta tubulin 0.0759 0.4488 0.5499
Echinococcus granulosus neuropeptide s receptor 0.0504 0.2945 0.35
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.022 0.0258
Echinococcus granulosus CREB binding protein 0.0018 0.0011 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0113 0.0584 0.0575
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0045 0.0042
Leishmania major gamma-tubulin 0.0465 0.2711 0.3317
Echinococcus granulosus CREB binding protein 0.0117 0.0611 0.0717
Echinococcus multilocularis thyroid hormone receptor alpha 0.0285 0.1622 0.1614
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1367 0.8154 1
Echinococcus multilocularis mothers against decapentaplegic 2 0.0022 0.0038 0.0028
Echinococcus multilocularis tubulin alpha chain 0.0536 0.3141 0.3134
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0073 0.0077
Brugia malayi beta-lactamase family protein 0.0039 0.0138 0.0157
Schistosoma mansoni tubulin subunit beta 0.0759 0.4488 0.5339
Echinococcus multilocularis tubulin alpha chain 0.0536 0.3141 0.3134
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0026 0.0019
Loa Loa (eye worm) hypothetical protein 0.0088 0.0436 0.0505
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Trichomonas vaginalis tubulin beta chain, putative 0.0759 0.4488 0.5504
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Schistosoma mansoni smad1 5 8 and 0.005 0.0205 0.0233
Echinococcus multilocularis CREB binding protein 0.0018 0.0011 0.0002
Brugia malayi Dihydrofolate reductase 0.0047 0.0189 0.022
Echinococcus granulosus mothers against decapentaplegic 6 0.0022 0.0038 0.0034
Trypanosoma brucei histone deacetylase 2 0.0427 0.2482 0.3036
Echinococcus granulosus tubulin subunit TubB 0.0536 0.3141 0.3733
Schistosoma mansoni hypothetical protein 0.0024 0.0045 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0211 0.0247
Echinococcus multilocularis Tubulin beta 2C chain 0.0759 0.4488 0.4483
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0606 0.4282
Echinococcus granulosus CREB binding protein 0.0018 0.0011 0.0002
Trypanosoma cruzi tubulin delta chain 0.0202 0.1122 0.1366
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0205 0.0233
Mycobacterium ulcerans hypothetical protein 0.0022 0.0034 0.0221
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0026 0.0019
Trichomonas vaginalis tubulin beta chain, putative 0.0536 0.3141 0.3852
Schistosoma mansoni cpg binding protein 0.0033 0.0101 0.0109
Trypanosoma brucei tubulin delta chain 0.0202 0.1122 0.1366
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0612 0.075
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Loa Loa (eye worm) thymidylate synthase 0.0116 0.0604 0.0711
Echinococcus multilocularis tubulin alpha 3 chain 0.0536 0.3141 0.3134
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0027 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0334 0.1922 0.2333
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0113 0.0584 0.0575
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0149 0.0801 0.0943
Echinococcus multilocularis Tubulin alpha 1 chain 0.0536 0.3141 0.3134
Schistosoma mansoni dihydrofolate reductase 0.0047 0.0189 0.0213
Echinococcus granulosus Tubulin beta 2C chain 0.0759 0.4488 0.5339
Echinococcus multilocularis beta tubulin 0.0759 0.4488 0.4483
Echinococcus granulosus transcription factor eb 0.0117 0.0607 0.0712
Echinococcus granulosus beta tubulin 0.0759 0.4488 0.5339
Brugia malayi BRCA1-associated protein 2 containing protein 0.0027 0.0064 0.0066
Loa Loa (eye worm) glutathione reductase 0.0051 0.0211 0.0229
Loa Loa (eye worm) tubulin beta-1 chain 0.0759 0.4488 0.549
Echinococcus granulosus chromobox protein 1 0.0075 0.0357 0.0414
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0116 0.0604 0.4263
Schistosoma mansoni Smad4 0.0022 0.0038 0.0034
Onchocerca volvulus 0.0033 0.0103 0.0149
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0027 0.0064 0.0066
Schistosoma mansoni tubulin subunit alpha 0.0536 0.3141 0.3733
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0113 0.0584 0.0575
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0065 0.0293 0.0284
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0113 0.0584 0.0575
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0176 0.0198
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0026 0.0019
Brugia malayi nuclear hormone receptor family member odr-7 0.0065 0.0293 0.0348
Mycobacterium tuberculosis Conserved protein 0.0039 0.0138 0.0918
Schistosoma mansoni smad 0.0022 0.0038 0.0034
Schistosoma mansoni tubulin subunit beta 0.0759 0.4488 0.5339
Echinococcus granulosus tubulin alpha chain 0.0536 0.3141 0.3733
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Echinococcus multilocularis tubulin epsilon chain 0.0465 0.2711 0.2704
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0113 0.0584 0.0705
Trichomonas vaginalis histone deacetylase, putative 0.1367 0.8154 1
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Loa Loa (eye worm) hypothetical protein 0.0042 0.0158 0.0162
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.0612 0.0739
Echinococcus multilocularis jun protein 0.0091 0.0451 0.0441
Schistosoma mansoni histone deacetylase 0.1367 0.8154 0.971
Trypanosoma brucei epsilon tubulin 0.0465 0.2711 0.3317
Brugia malayi hypoxia-induced factor 1 0.0163 0.0885 0.1075
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0096 0.0481 0.0578
Brugia malayi hypothetical protein 0.0084 0.041 0.0492
Echinococcus multilocularis musashi 0.0029 0.0079 0.0069
Loa Loa (eye worm) beta-tubulin 0.0759 0.4488 0.549
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0079 0.0065
Loa Loa (eye worm) p25-alpha family protein 0.0395 0.229 0.2786
Brugia malayi MH1 domain containing protein 0.0028 0.007 0.0074
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0273 0.1552 0.1903
Loa Loa (eye worm) BEN-1 protein 0.0759 0.4488 0.549
Echinococcus granulosus histone deacetylase 7 0.0549 0.3217 0.3823
Echinococcus multilocularis dihydrofolate reductase 0.0047 0.0189 0.0179
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0293 0.0338
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0091 0.0451 0.0526
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0084 0.041 0.0477
Echinococcus granulosus tubulin alpha chain 0.0536 0.3141 0.3733
Echinococcus multilocularis CREB binding protein 0.0018 0.0011 0.0002
Entamoeba histolytica tubulin family protein 0.0759 0.4488 0.549
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0138 0.0157
Toxoplasma gondii beta-1 tubulin, putative 0.0759 0.4488 0.5499
Schistosoma mansoni tubulin subunit alpha 0.0536 0.3141 0.3733
Brugia malayi Histone deacetylase 1 0.1367 0.8154 1
Leishmania major cytochrome p450-like protein 0.0025 0.0052 0.0052
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0052 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0149 0.0801 0.0953
Plasmodium vivax tubulin alpha chain, putative 0.0536 0.3141 0.3845
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0138 0.095
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Echinococcus granulosus histone deacetylase 6 0.0549 0.3217 0.3823
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0177 0.031
Brugia malayi hypothetical protein 0.0299 0.1706 0.2083
Mycobacterium tuberculosis Hypothetical protein 0.0055 0.0236 0.1626
Echinococcus granulosus BRCA1 associated protein 0.0027 0.0064 0.0064
Schistosoma mansoni CREB-binding protein 2 0.0117 0.0611 0.0717
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0027 0.0064 0.0066
Onchocerca volvulus Bile acid receptor homolog 0.0149 0.0801 0.1668
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0149 0.0801 0.0943
Trypanosoma brucei beta tubulin 0.0759 0.4488 0.5499
Trichomonas vaginalis tubulin, putative 0.0759 0.4488 0.5504
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0357 0.0438
Brugia malayi follicle stimulating hormone receptor 0.0255 0.1445 0.1762
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Echinococcus granulosus tubulin alpha chain 0.0536 0.3141 0.3733
Loa Loa (eye worm) hypothetical protein 0.0084 0.041 0.0473
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0403 0.3388
Treponema pallidum cell division protein FtsZ 0.0202 0.1122 1
Trypanosoma cruzi beta tubulin, putative 0.0759 0.4488 0.5499
Schistosoma mansoni Smad4 0.0022 0.0038 0.0034
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0055 0.0236 0.0278
Plasmodium falciparum tubulin beta chain 0.0759 0.4488 0.5499
Loa Loa (eye worm) alpha-tubulin 0.0536 0.3141 0.3833
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Echinococcus granulosus histone deacetylase 3 0.1367 0.8154 0.971
Schistosoma mansoni tubulin subunit beta 0.0759 0.4488 0.5339
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0095
Echinococcus multilocularis isocitrate dehydrogenase 0.0113 0.0584 0.0575
Echinococcus granulosus tubulin beta 1 chain 0.0759 0.4488 0.5339
Mycobacterium ulcerans hypothetical protein 0.0039 0.0138 0.1151
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0138 0.0153
Loa Loa (eye worm) nuclear receptor NHR-67 0.0065 0.0293 0.0329
Schistosoma mansoni cpg binding protein 0.0031 0.009 0.0096
Echinococcus granulosus Tubulin beta 2C chain 0.0759 0.4488 0.5339
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0149 0.0801 0.0943
Loa Loa (eye worm) hypothetical protein 0.0051 0.0213 0.0231
Echinococcus multilocularis Smad4 0.005 0.0205 0.0196
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0136 0.0724 0.0852
Loa Loa (eye worm) hypothetical protein 0.0116 0.0604 0.0711
Loa Loa (eye worm) nuclear factor I 0.0028 0.007 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0201 0.0228
Echinococcus multilocularis histone deacetylase 6 0.0549 0.3217 0.321
Mycobacterium ulcerans beta-lactamase 0.0039 0.0138 0.1151
Schistosoma mansoni transcription factor LCR-F1 0.0299 0.1706 0.2023
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0211 0.0247
Brugia malayi Tubulin gamma chain 0.0465 0.2711 0.3317
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Schistosoma mansoni retinoic acid receptor RXR 0.0255 0.1444 0.1709
Loa Loa (eye worm) nuclear hormone receptor 0.0065 0.0293 0.0329
Loa Loa (eye worm) tubulin alpha-2 chain 0.0536 0.3141 0.3833
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0027 0.0064 0.0064
Loa Loa (eye worm) isocitrate dehydrogenase 0.0113 0.0584 0.0687
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0138 0.1151
Echinococcus granulosus histone deacetylase 1 0.1367 0.8154 0.971
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Leishmania major histone deacetylase, putative 0.0549 0.3217 0.3937
Echinococcus multilocularis muscleblind protein 0.0161 0.0877 0.0868
Loa Loa (eye worm) beta-lactamase 0.0039 0.0138 0.0138
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0113 0.0584 0.0705
Brugia malayi intermediate filament protein 0.0029 0.0079 0.0085
Echinococcus granulosus tubulin alpha chain 0.0536 0.3141 0.3733
Brugia malayi Flap endonuclease-1 0.0028 0.0073 0.0077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0027 0.0064 0.0047
Schistosoma mansoni alpha tubulin 0.0536 0.3141 0.3733
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.0612 0.0718
Trypanosoma brucei beta tubulin 0.0759 0.4488 0.5499
Echinococcus granulosus tubulin subunit beta 0.0759 0.4488 0.5339
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0149 0.0801 0.0953
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Echinococcus multilocularis Tubulin beta 2C chain 0.0759 0.4488 0.4483
Loa Loa (eye worm) BEN-1 protein 0.0759 0.4488 0.549
Echinococcus granulosus tubulin alpha 3 chain 0.0536 0.3141 0.3733
Giardia lamblia Gamma tubulin 0.0465 0.2711 0.3317
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0113 0.0584 0.0685
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0149 0.0801 0.0943
Echinococcus multilocularis histone deacetylase 1 0.1367 0.8154 0.8152
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0149 0.0801 0.0953
Trichomonas vaginalis histone deacetylase, putative 0.1367 0.8154 1
Loa Loa (eye worm) tubulin alpha 2 0.0334 0.1922 0.2333
Toxoplasma gondii exonuclease III APE 0.002 0.0026 0.0019
Giardia lamblia Histone acetyltransferase GCN5 0.0086 0.0422 0.0506
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0293 0.0338
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0293 0.0284
Onchocerca volvulus TPPP family protein homolog 0.0395 0.229 0.491
Plasmodium falciparum alpha tubulin 2 0.0536 0.3141 0.3845
Plasmodium vivax histone deacetylase, putative 0.0549 0.3217 0.3937
Mycobacterium tuberculosis Conserved protein 0.0039 0.0138 0.0918
Brugia malayi hypothetical protein 0.0065 0.0293 0.0348
Brugia malayi Tubulin alpha chain 0.0202 0.1122 0.1366
Schistosoma mansoni nuclear hormone receptor 0.0149 0.0801 0.0943
Schistosoma mansoni single-minded 0.0053 0.022 0.0251
Loa Loa (eye worm) hypothetical protein 0.0033 0.0102 0.0094
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0027 0.0064 0.0066
Toxoplasma gondii beta tubulin 0.0759 0.4488 0.5499
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0149 0.0801 0.0971
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.022 0.0258
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0102 0.011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0102 0.0092
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0026 0.0142
Echinococcus multilocularis Tubulin beta 2C chain 0.0759 0.4488 0.4483
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Loa Loa (eye worm) histone deacetylase 1 0.1367 0.8154 1
Entamoeba histolytica hypothetical protein 0.0299 0.1706 0.2068
Echinococcus multilocularis chromobox protein 1 0.0075 0.0357 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0083 0.0102
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0047 0.0189 0.1419
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0149 0.0801 0.0792
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0138 0.0157
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0102 0.011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0094 0.0104
Onchocerca volvulus 0.0149 0.0801 0.1668
Schistosoma mansoni hypothetical protein 0.1407 0.8398 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.009 0.0096
Trypanosoma brucei histone deacetylase 4 0.0549 0.3217 0.3937
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.022 0.0258
Brugia malayi alpha-tubulin 0.0536 0.3141 0.3845
Mycobacterium tuberculosis Conserved protein 0.0039 0.0138 0.0918
Echinococcus multilocularis tubulin alpha 1C chain 0.0536 0.3141 0.3134
Brugia malayi beta-lactamase family protein 0.0039 0.0138 0.0157
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0612 0.0721
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0249 0.1403 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0759 0.4488 0.4483
Loa Loa (eye worm) hypothetical protein 0.0427 0.2482 0.3022
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Echinococcus granulosus thymidylate synthase 0.0116 0.0604 0.0708
Echinococcus granulosus histone acetyltransferase KAT2B 0.0096 0.0481 0.0561
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0612 0.0718
Plasmodium vivax delta tubulin, putative 0.0202 0.1122 0.1366
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0138 0.0169
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0026 0.0031
Brugia malayi Tubulin alpha-2 chain 0.0536 0.3141 0.3845
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0047 0.0189 0.1609
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0324 0.0385
Echinococcus granulosus histone acetyltransferase KAT2B 0.031 0.1774 0.2104
Schistosoma mansoni RAR-like nuclear receptor 0.0149 0.0801 0.0943
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0027 0.0064 0.0047
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.0612 0.531
Schistosoma mansoni smad1 5 8 and 0.005 0.0205 0.0233
Brugia malayi 6-phosphofructokinase 0.0117 0.0612 0.0739
Plasmodium falciparum glutathione reductase 0.0051 0.0211 0.0247
Schistosoma mansoni tubulin subunit beta 0.0759 0.4488 0.5339
Echinococcus multilocularis tumor protein p63 0.0365 0.2107 0.2099
Brugia malayi Cell division protein ftsZ 0.0202 0.1122 0.1366
Echinococcus granulosus CREB binding protein 0.0075 0.0358 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0149 0.0801 0.0792
Schistosoma mansoni chromobox protein 0.0075 0.0357 0.0414
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0034 0.0177
Schistosoma mansoni jun-related protein 0.0074 0.0348 0.0403
Trichomonas vaginalis tubulin gamma chain, putative 0.0202 0.1122 0.1376
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0138 0.0157
Echinococcus granulosus tubulin epsilon chain 0.0465 0.2711 0.322
Brugia malayi phosphofructokinase 0.0117 0.0612 0.0739
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0612 0.0721
Trypanosoma brucei trypanothione reductase 0.0051 0.0211 0.0247
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0073 0.0063
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Loa Loa (eye worm) tubulin alpha-3 chain 0.0273 0.1552 0.1878
Trypanosoma cruzi zeta tubulin, putative 0.0202 0.1122 0.1366
Schistosoma mansoni hypothetical protein 0.0074 0.0348 0.0403
Giardia lamblia Delta tubulin 0.0202 0.1122 0.1366
Loa Loa (eye worm) hypothetical protein 0.0028 0.007 0.0055
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.0612 0.5414
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0149 0.0801 0.0971
Onchocerca volvulus 0.0039 0.0141 0.0232
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.0612 0.0603
Schistosoma mansoni thyroid hormone receptor 0.0285 0.1622 0.1922
Echinococcus multilocularis FTZ F1 alpha 0.0149 0.0801 0.0792
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0403 0.2821
Loa Loa (eye worm) tubulin beta chain 0.0759 0.4488 0.549
Brugia malayi hypothetical protein 0.0176 0.0967 0.1176
Mycobacterium ulcerans lipase LipD 0.0039 0.0138 0.1151
Brugia malayi ecdysone receptor 0.0065 0.0293 0.0348
Mycobacterium tuberculosis Probable oxidoreductase 0.013 0.0685 0.4845
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.001 0.0012
Brugia malayi hypothetical protein 0.0071 0.0333 0.0397
Schistosoma mansoni tubulin subunit alpha 0.0536 0.3141 0.3733
Brugia malayi tailless protein 0.0065 0.0293 0.0348
Schistosoma mansoni cpg binding protein 0.0033 0.0101 0.0109
Schistosoma mansoni alpha tubulin 0.0536 0.3141 0.3733
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0084 0.041 0.0473
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0011
Trichomonas vaginalis tubulin epsilon chain, putative 0.0536 0.3141 0.3852
Schistosoma mansoni nuclear receptor 0.0065 0.0293 0.0338
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0263 0.1492 0.1829
Entamoeba histolytica acetyltransferase, GNAT family 0.0086 0.0422 0.0488
Schistosoma mansoni histone deacetylase 0.1367 0.8154 0.971
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.022 0.0258
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0079 0.0065
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0084 0.041 0.0477
Brugia malayi MH2 domain containing protein 0.005 0.0205 0.024
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0027 0.0064 0.0064
Trypanosoma cruzi tubulin delta chain 0.0202 0.1122 0.1366
Brugia malayi glutathione reductase 0.0051 0.0211 0.0247
Echinococcus multilocularis neuropeptide s receptor 0.0504 0.2945 0.2938
Schistosoma mansoni smad 0.005 0.0205 0.0233
Brugia malayi tubulin alpha chain - mouse 0.0536 0.3141 0.3845
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0138 0.0918
Schistosoma mansoni smad1 5 8 and 0.005 0.0205 0.0233
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0117 0.0607 0.0733
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0096 0.0481 0.0578
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0138 0.0138
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0255 0.1445 0.1746
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0027 0.0064 0.0066
Brugia malayi Heterochromatin protein 1 0.0075 0.0357 0.0427
Entamoeba histolytica tubulin gamma chain 0.0465 0.2711 0.3304
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0205 0.0221
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0027 0.0064 0.0066
Loa Loa (eye worm) dihydrofolate reductase 0.0047 0.0189 0.0201
Brugia malayi nuclear hormone receptor family member nhr-6 0.0065 0.0293 0.0348
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0138 0.0918
Plasmodium falciparum histone deacetylase 1 0.1367 0.8154 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0149 0.0801 0.1668
Onchocerca volvulus 0.0065 0.0293 0.0564
Mycobacterium ulcerans thymidylate synthase 0.0116 0.0604 0.534
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0113 0.0584 0.4121
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0064 0.0066
Loa Loa (eye worm) tubulin beta chain 0.0202 0.1122 0.1349
Loa Loa (eye worm) hypothetical protein 0.0083 0.0403 0.0464
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0102 0.0092
Echinococcus granulosus nuclear receptor nhr 48 0.0065 0.0293 0.0338
Trichomonas vaginalis tubulin beta chain, putative 0.0536 0.3141 0.3852
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0149 0.0801 0.0971
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0027 0.0064 0.0066
Trypanosoma brucei zeta tubulin, putative 0.0202 0.1122 0.1366
Echinococcus multilocularis tubulin delta chain 0.0202 0.1122 0.1113
Brugia malayi steroid hormone receptor 0.0149 0.0801 0.0971
Schistosoma mansoni nuclear receptor nhr-48 0.0065 0.0293 0.0338
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0027 0.0064 0.0047
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0096 0.0481 0.0578
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0612 0.075
Trypanosoma cruzi epsilon tubulin, putative 0.0465 0.2711 0.3317
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0064 0.0066
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0321 0.184 0.2182
Echinococcus multilocularis CREB binding protein 0.0018 0.0011 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0149 0.0801 0.0943
Onchocerca volvulus 0.0039 0.0138 0.0225
Echinococcus multilocularis tubulin subunit beta 0.0759 0.4488 0.4483
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0244 0.0269
Toxoplasma gondii histone deacetylase HDAC4 0.0427 0.2482 0.3036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0201 0.0192
Loa Loa (eye worm) hypothetical protein 0.0084 0.041 0.0473
Trichomonas vaginalis esterase, putative 0.0039 0.0138 0.0169
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0138 0.0157
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0073 0.0077
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0034 0.003
Giardia lamblia Beta tubulin 0.0759 0.4488 0.5499
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0026 0.0019
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0027 0.0064 0.0054
Brugia malayi MH1 domain containing protein 0.005 0.0205 0.024
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0073 0.0089
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0065 0.0293 0.0338
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.013 0.0685 0.4845
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0171 0.0936 0.0928
Leishmania major epsilon tubulin, putative 0.0465 0.2711 0.3317
Schistosoma mansoni ap endonuclease 0.002 0.0026 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0149 0.0801 0.0953
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.022 0.0258
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0047 0.0189 0.1284
Loa Loa (eye worm) hypothetical protein 0.0039 0.0138 0.0138
Echinococcus multilocularis tubulin alpha chain 0.0536 0.3141 0.3134
Echinococcus granulosus histone deacetylase 8 0.0427 0.2482 0.2948
Loa Loa (eye worm) hypothetical protein 0.0273 0.1552 0.1878
Plasmodium vivax glutathione reductase, putative 0.0051 0.0211 0.0247
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0138 0.0157
Echinococcus multilocularis tubulin alpha 0.0465 0.2711 0.2704
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0149 0.0801 0.0971
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0038 0.0015
Plasmodium falciparum tubulin epsilon chain, putative 0.0465 0.2711 0.3317
Echinococcus multilocularis tubulin alpha chain 0.0536 0.3141 0.3134
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0163 0.089 0.108
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.0039 0.0138 0.0138
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.0606 0.4282
Echinococcus multilocularis tubulin subunit TubB 0.0536 0.3141 0.3134
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0027 0.0064 0.0066
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0113 0.0584 0.0705
Brugia malayi Tubulin alpha chain 0.0536 0.3141 0.3845
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0091 0.0451 0.0441
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0026 0.0019
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0073 0.0077
Entamoeba histolytica tubulin alpha-1 chain 0.0536 0.3141 0.3833
Giardia lamblia Alpha-tubulin 0.0536 0.3141 0.3845
Trichomonas vaginalis tubulin alpha chain, putative 0.0263 0.1492 0.1829
Brugia malayi TAZ zinc finger family protein 0.0117 0.0611 0.0739
Trypanosoma cruzi histone deacetylase, putative 0.0549 0.3217 0.3937
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Brugia malayi Histone deacetylase family protein 0.0549 0.3217 0.3937
Loa Loa (eye worm) Smad1 0.005 0.0205 0.0221
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0158 0.0268
Brugia malayi CXXC zinc finger family protein 0.0031 0.009 0.0099
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.0606 0.4282
Brugia malayi Tubulin beta chain 0.0263 0.1492 0.182
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0201 0.0235
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.013 0.0685 0.5982
Loa Loa (eye worm) tubulin alpha chain 0.0536 0.3141 0.3833
Onchocerca volvulus 0.0257 0.1452 0.3086
Entamoeba histolytica histone deacetylase, putative 0.1367 0.8154 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0138 0.0918
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.1122 0.1376
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0094 0.0761
Brugia malayi mothers against decapentaplegic homolog 3 0.0022 0.0038 0.0035
Echinococcus multilocularis lamin dm0 0.0029 0.0079 0.0069
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Echinococcus multilocularis chromobox protein 1 0.0075 0.0357 0.0348
Brugia malayi nuclear hormone receptor 0.0065 0.0293 0.0348
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0177 0.0217
Schistosoma mansoni tubulin subunit beta 0.0759 0.4488 0.5339
Echinococcus granulosus tubulin beta 4A class IVa 0.0759 0.4488 0.5339
Trypanosoma cruzi histone deacetylase 1, putative 0.1367 0.8154 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0149 0.0801 0.0792
Leishmania major hypothetical protein, conserved 0.0027 0.0064 0.0066
Brugia malayi histone deacetylase 11 0.0427 0.2482 0.3036
Plasmodium falciparum histone deacetylase, putative 0.0549 0.3217 0.3937
Trichomonas vaginalis tubulin alpha chain, putative 0.0465 0.2711 0.3325
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0403 0.0483
Brugia malayi Thioredoxin reductase 0.0051 0.0211 0.0247
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0094 0.0104
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0357 0.0438
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0202 0.1122 0.1366
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0084 0.041 0.0401
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0045 0.0035
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Schistosoma mansoni lamin 0.0029 0.0079 0.0082
Trypanosoma cruzi zeta tubulin, putative 0.0202 0.1122 0.1366
Mycobacterium ulcerans cell division protein FtsZ 0.0202 0.1122 1
Echinococcus granulosus histone deacetylase 6 0.0549 0.3217 0.3823
Trichomonas vaginalis bromodomain-containing protein, putative 0.0096 0.0481 0.0589
Echinococcus multilocularis muscleblind protein 1 0.0161 0.0877 0.0868
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0201 0.0192
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0149 0.0801 0.0943
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0116 0.0604 0.0711
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0307 0.0355
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0321 0.184 0.1832
Schistosoma mansoni hypothetical protein 0.1407 0.8398 1
Schistosoma mansoni tubulin subunit delta 0.0202 0.1122 0.1326
Loa Loa (eye worm) hypothetical protein 0.0536 0.3141 0.3833
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0027 0.0064 0.0054
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0027 0.0064 0.0064
Echinococcus granulosus geminin 0.1407 0.8398 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0224 0.0255
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0027 0.0064 0.0066
Echinococcus granulosus Tubulin alpha 1 chain 0.0536 0.3141 0.3733
Brugia malayi MH1 domain containing protein 0.0028 0.007 0.0074
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0211 0.0229
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.041 0.0492
Brugia malayi hypothetical protein 0.0065 0.0293 0.0348
Schistosoma mansoni tubulin subunit gamma 0.0465 0.2711 0.322
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0027 0.0064 0.0066
Plasmodium vivax tubulin gamma chain, putative 0.0465 0.2711 0.3317
Trichomonas vaginalis tubulin epsilon chain, putative 0.0536 0.3141 0.3852
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0225 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0149 0.0801 0.0971
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0612 0.0721
Loa Loa (eye worm) histone deacetylase 7A 0.0549 0.3217 0.3926
Brugia malayi dihydrofolate reductase family protein 0.0047 0.0189 0.022
Trichomonas vaginalis tubulin gamma chain, putative 0.0465 0.2711 0.3325
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.1122 0.1376
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0073 0.0058
Trypanosoma brucei histone deacetylase 1 0.1367 0.8154 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0211 0.0202
Brugia malayi conserved hypotetical protein 0.0065 0.0293 0.0348
Loa Loa (eye worm) histone deacetylase 0.0549 0.3217 0.3926
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0357 0.0408
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.022 0.0258
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0116 0.0604 0.5235
Echinococcus granulosus histone deacetylase 0.0549 0.3217 0.3823
Onchocerca volvulus 0.0065 0.0293 0.0564
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.002 0.0024
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0094 0.2154
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0205 0.0221
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0612 0.0721
Schistosoma mansoni tubulin subunit beta 0.0202 0.1122 0.1326
Echinococcus multilocularis histone deacetylase 3 0.1367 0.8154 0.8152
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.009 0.008
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0052 0.0052
Brugia malayi Cytochrome P450 family protein 0.0025 0.0052 0.0052
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0052 0.0033
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0094 0.0104
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0102 0.0113
Brugia malayi hypothetical protein 0.0034 0.0108 0.012
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0149 0.0801 0.0943
Plasmodium vivax histone deacetylase 2, putative 0.0549 0.3217 0.3937
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0094 0.0104
Mycobacterium ulcerans endonuclease IV 0.0083 0.0403 0.3534
Trichomonas vaginalis brca1-associated protein, putative 0.0027 0.0064 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0612 0.075
Mycobacterium leprae cell division protein FtsZ 0.0202 0.1122 1
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Echinococcus multilocularis thymidylate synthase 0.0116 0.0604 0.0595
Entamoeba histolytica hypothetical protein 0.0299 0.1706 0.2068
Plasmodium falciparum tubulin delta chain, putative 0.0202 0.1122 0.1366
Trypanosoma cruzi histone deacetylase, putative 0.0427 0.2482 0.3036
Trichomonas vaginalis tubulin beta chain, putative 0.0536 0.3141 0.3852
Brugia malayi nuclear receptor RXR 0.0084 0.041 0.0492
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0138 0.1151
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.041 0.0477
Schistosoma mansoni histone deacetylase hda2 0.0427 0.2482 0.2948
Echinococcus granulosus mothers against decapentaplegic 2 0.0022 0.0038 0.0034
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0026 0.0113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0102 0.011
Brugia malayi Smad1 0.005 0.0205 0.024
Schistosoma mansoni lamin 0.0029 0.0079 0.0082
Trypanosoma brucei alpha tubulin 0.0536 0.3141 0.3845
Loa Loa (eye worm) pax transcription factor protein 2 0.0783 0.4628 0.5662
Trypanosoma brucei epsilon tubulin 0.0465 0.2711 0.3317
Chlamydia trachomatis dihydrofolate reductase 0.0047 0.0189 0.4552
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0211 0.024
Echinococcus granulosus beta tubulin 0.0759 0.4488 0.5339
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0293 0.0348
Trypanosoma brucei beta tubulin 0.0759 0.4488 0.5499
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Trichomonas vaginalis tubulin gamma chain, putative 0.0759 0.4488 0.5504
Brugia malayi Tubulin beta-1 chain 0.0759 0.4488 0.5499
Echinococcus granulosus tubulin alpha 3 chain 0.0536 0.3141 0.3733
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0027 0.0064 0.0066
Schistosoma mansoni chromobox protein 0.0075 0.0357 0.0414
Plasmodium vivax histone deacetylase, putative 0.0427 0.2482 0.3036
Echinococcus multilocularis mothers against decapentaplegic 6 0.0022 0.0038 0.0028
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.0246
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Echinococcus granulosus tubulin alpha chain 0.0536 0.3141 0.3733
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0149 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0239
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0205 0.0233
Echinococcus multilocularis histone deacetylase 0.0549 0.3217 0.321
Echinococcus multilocularis histone deacetylase 7 0.0549 0.3217 0.321
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0026 0.0019
Plasmodium falciparum tubulin gamma chain 0.0465 0.2711 0.3317
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0205 0.0196
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0163 0.089 0.108
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0113 0.0584 0.0705
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0149 0.0801 0.0943
Loa Loa (eye worm) tubulin beta-2A chain 0.0759 0.4488 0.549
Brugia malayi nuclear receptor NHR-88 0.0065 0.0293 0.0348
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0094 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.002 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0064 0.0078
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0117 0.0611 0.0717
Brugia malayi histone deacetylase 1 (HD1) 0.1367 0.8154 1
Leishmania major histone deacetylase, putative 0.1367 0.8154 1
Giardia lamblia Histone deacetylase 0.1367 0.8154 1
Leishmania major alpha tubulin 0.0536 0.3141 0.3845
Trypanosoma brucei histone deacetylase 3 0.0549 0.3217 0.3937
Echinococcus multilocularis cpg binding protein 0.0033 0.0101 0.0091
Echinococcus granulosus muscleblind protein 0.0161 0.0877 0.1034
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Plasmodium falciparum histone deacetylase 2 0.0549 0.3217 0.3937
Brugia malayi PAS domain containing protein 0.0053 0.022 0.0258
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0094 0.0085
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0293 0.0564
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0027 0.0064 0.0064
Trichomonas vaginalis tubulin epsilon chain, putative 0.0202 0.1122 0.1376
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0094 0.0116
Entamoeba histolytica hypothetical protein 0.0299 0.1706 0.2068
Schistosoma mansoni histone deacetylase hda2 0.0576 0.3377 0.4015
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0201 0.0216
Loa Loa (eye worm) tubulin alpha chain 0.0536 0.3141 0.3833
Echinococcus multilocularis hypothetical protein 0.0536 0.3141 0.3134
Echinococcus multilocularis tubulin alpha chain 0.0536 0.3141 0.3134
Echinococcus granulosus Tubulin alpha 1 chain 0.0536 0.3141 0.3733
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0202 0.1122 0.1376
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0065 0.0293 0.0338
Giardia lamblia Epsilon tubulin 0.0202 0.1122 0.1366
Plasmodium vivax tubulin epsilon chain, putative 0.0465 0.2711 0.3317
Echinococcus granulosus tubulin alpha 1C chain 0.0536 0.3141 0.3733
Trichomonas vaginalis BRCA1-associated protein, putative 0.0027 0.0064 0.0078
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0293 0.0564
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0026 0.0142
Schistosoma mansoni thyroid hormone receptor 0.0285 0.1622 0.1922
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.1265 0.1524
Loa Loa (eye worm) tubulin alpha 2 0.0071 0.0333 0.0378
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0177 0.0217
Loa Loa (eye worm) DR-78 0.0065 0.0293 0.0329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0064 0.0078
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0138 0.0128
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0096 0.0481 0.0589
Brugia malayi ecdysteroid receptor 0.0149 0.0801 0.0971
Toxoplasma gondii histone deacetylase HDAC3 0.1367 0.8154 1
Echinococcus granulosus Smad4 0.005 0.0205 0.0233
Brugia malayi MH2 domain containing protein 0.0022 0.0038 0.0035
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0073 0.0077
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0163 0.089 0.108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0201 0.0228
Schistosoma mansoni hypothetical protein 0.0136 0.0724 0.0852
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0149 0.0801 0.0792
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0465 0.2711 0.3317
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0201 0.0228
Plasmodium vivax SET domain protein, putative 0.0033 0.0102 0.0113
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Schistosoma mansoni hypothetical protein 0.0116 0.0603 0.0707
Loa Loa (eye worm) hypoxia-induced factor 1 0.0163 0.0885 0.1057
Trypanosoma brucei epsilon tubulin 0.0465 0.2711 0.3317
Echinococcus granulosus tubulin alpha 0.0465 0.2711 0.322
Leishmania major beta tubulin 0.0759 0.4488 0.5499
Trypanosoma cruzi histone deacetylase 1, putative 0.1367 0.8154 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0334 0.1922 0.2357
Brugia malayi Tubulin beta chain 0.0202 0.1122 0.1366
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0065 0.0293 0.0329
Trichomonas vaginalis set domain proteins, putative 0.0257 0.1452 0.1781
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Brugia malayi Nuclear hormone receptor-like 1 0.0149 0.0801 0.0971
Giardia lamblia Beta tubulin 0.0759 0.4488 0.5499
Loa Loa (eye worm) hypothetical protein 0.0065 0.0293 0.0329
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0293 0.0284
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0149 0.0801 0.0943
Brugia malayi Pre-SET motif family protein 0.0226 0.1265 0.1541
Toxoplasma gondii endonuclease IV APN 0.0083 0.0403 0.0483
Trichomonas vaginalis histone deacetylase, putative 0.1367 0.8154 1
Brugia malayi nuclear receptor RXR 0.0065 0.0293 0.0348
Echinococcus granulosus alpha tubulin 0.0536 0.3141 0.3733
Loa Loa (eye worm) hypothetical protein 0.0149 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.0084 0.041 0.0473
Brugia malayi chromobox protein homolog 3 0.0042 0.0158 0.0182
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0064 0.0066
Plasmodium falciparum histone acetyltransferase GCN5 0.0086 0.0422 0.0506
Leishmania major histone deacetylase, putative 0.1367 0.8154 1
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0334 0.1922 0.2333
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0027 0.0064 0.0047
Loa Loa (eye worm) hypothetical protein 0.0122 0.0637 0.0752
Echinococcus granulosus lamin 0.0029 0.0079 0.0082
Giardia lamblia Alpha-tubulin 0.0536 0.3141 0.3845
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0064 0.0066
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0138 0.1151
Trypanosoma brucei alpha tubulin 0.0536 0.3141 0.3845
Trypanosoma brucei tubulin gamma chain 0.0465 0.2711 0.3317
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0163 0.089 0.108
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0113 0.0584 0.0705
Brugia malayi acetyltransferase, GNAT family protein 0.0321 0.184 0.2247
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0149 0.0801 0.1668
Trypanosoma cruzi alpha tubulin, putative 0.0536 0.3141 0.3845
Schistosoma mansoni tubulin subunit beta 0.0759 0.4488 0.5339
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0026 0.0142
Schistosoma mansoni brca1-associated protein (brap2) 0.0027 0.0064 0.0064
Loa Loa (eye worm) histone deacetylase 11 0.0427 0.2482 0.3022
Echinococcus granulosus lamin dm0 0.0029 0.0079 0.0082
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0052 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.0504 0.2945 0.2938
Onchocerca volvulus 0.0029 0.0079 0.0097
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0163 0.089 0.108
Echinococcus granulosus Tubulin beta 2C chain 0.0759 0.4488 0.5339
Trypanosoma brucei alpha tubulin 0.0536 0.3141 0.3845
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0606 0.4282
Brugia malayi tubulin alpha-2 chain 0.0536 0.3141 0.3845
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.041 0.0492
Loa Loa (eye worm) tubulin alpha 2 0.0334 0.1922 0.2333
Trypanosoma cruzi tubulin gamma chain 0.0465 0.2711 0.3317
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.0612 0.5414
Mycobacterium ulcerans epimerase 0.0022 0.0034 0.0221
Toxoplasma gondii thioredoxin reductase 0.0051 0.0211 0.0247
Brugia malayi MH1 domain containing protein 0.005 0.0205 0.024
Loa Loa (eye worm) MH2 domain-containing protein 0.0735 0.4343 0.5311
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0094 0.0104
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.0606 0.4282
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0027 0.0064 0.0066
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0138 0.0918
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0403 0.0483
Echinococcus granulosus neuropeptide receptor A26 0.0504 0.2945 0.35
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0052 0.0052
Schistosoma mansoni tubulin subunit alpha 0.0202 0.1122 0.1326
Brugia malayi Isocitrate dehydrogenase 0.0113 0.0584 0.0705
Schistosoma mansoni histone deacetylase 1 2 3 0.0427 0.2482 0.2948
Trichomonas vaginalis histone deacetylase, putative 0.1367 0.8154 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0158 0.0193

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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