Detailed information for compound 822438

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 426.532 | Formula: C22H26N4O3S
  • H donors: 2 H acceptors: 4 LogP: 3.25 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCN(C(=O)c1sc2c(c1C)c(NCC1CCCO1)ncn2)Cc1ccccc1
  • InChi: 1S/C22H26N4O3S/c1-15-18-20(23-12-17-8-5-11-29-17)24-14-25-21(18)30-19(15)22(28)26(9-10-27)13-16-6-3-2-4-7-16/h2-4,6-7,14,17,27H,5,8-13H2,1H3,(H,23,24,25)
  • InChiKey: JNWXTRSSFJGPRD-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi copper-transporting ATPase, putative 0.0009 0.0077 0.038
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0703 0.3422
Trypanosoma cruzi multidrug resistance protein E, putative 0.0006 0.0017 0.0083
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.011 0.0269
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0124 0.0306
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0703 0.103
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.043 0.2072
Entamoeba histolytica hypothetical protein 0.0007 0.0029 0.0144
Schistosoma mansoni type V p-type atpase isoform 0.0009 0.0077 0.0158
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.0322
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Loa Loa (eye worm) hypothetical protein 0.0015 0.0212 0.0212
Brugia malayi ABC transporter transmembrane region family protein 0.0006 0.0017 0.0005
Brugia malayi hypothetical protein 0.0137 0.2847 0.2838
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0176 0.0793
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Onchocerca volvulus 0.0137 0.2847 0.5297
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Brugia malayi RasGEF domain containing protein 0.0007 0.0029 0.0017
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0077 0.0322
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0177 0.0177
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0009 0.0077 0.0178
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0009 0.0077 0.0879
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0703 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0212 0.0212
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0109 0.0536
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0009 0.0077 0.0879
Schistosoma mansoni gabp alpha 0.0076 0.1529 0.3136
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0725 0.3517
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0009 0.0077 0.0879
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.063 0.3102
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.038
Loa Loa (eye worm) steroid hormone receptor 0.0029 0.0505 0.0505
Schistosoma mansoni cation-transporting ATPase 0.0009 0.0077 0.0158
Onchocerca volvulus 0.0009 0.0077 0.009
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0009 0.0077 0.0166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0703 0.0703
Brugia malayi Ets-domain containing protein 0.0076 0.1529 0.1519
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0007 0.0029 0.006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.011 0.157
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0244 0.0624
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0725 0.1945
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0177 0.0364
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0009 0.0077 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0029 0.0505 0.0493
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0116 0.0571
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0177 0.0453
Loa Loa (eye worm) hypothetical protein 0.0093 0.1886 0.1886
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0177 0.0165
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0703 0.1347
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0009 0.0077 0.038
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0014 0.0183 0.0844
Onchocerca volvulus 0.0009 0.0087 0.0109
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0077 0.0322
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0703 0.0691
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0254 0.0356
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0009 0.0077 0.0879
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0012
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0183 0.0844
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0006 0.0017 0.0035
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0244 0.05
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0006 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0109
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0703 0.1347
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0505 0.1351
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0009 0.0077 0.0166
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0176 0.0793
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.203 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0244 0.5153
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0644 0.0644
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0017 0.0083
Mycobacterium tuberculosis Conserved protein 0.0038 0.0703 0.1347
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0009 0.0077 0.1099
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0177 0.0441
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0458 0.6512
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0626 0.3083
Entamoeba histolytica ABC transporter, putative 0.0006 0.0017 0.0083
Schistosoma mansoni rotamase 0.0035 0.0644 0.132
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0183 0.0844
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.0322
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0109 0.0478
Chlamydia trachomatis DNA ligase 0.001 0.0109 0.3002
Entamoeba histolytica hypothetical protein 0.001 0.0109 0.0536
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.038
Echinococcus multilocularis cation transporting ATPase 13A3 0.0009 0.0077 0.0166
Leishmania major copper-transporting ATPase-like protein, putative 0.0009 0.0077 0.03
Trypanosoma cruzi P-type H+-ATPase, putative 0.0009 0.0077 0.038
Toxoplasma gondii cation-transporting atpase family protein 0.0009 0.0077 0.1099
Echinococcus granulosus bloom syndrome protein 0.0025 0.043 0.1147
Trypanosoma brucei membrane transporter protein, putative 0.0035 0.063 0.3044
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0014 0.0183 0.0467
Schistosoma mansoni topbp1 0.001 0.0109 0.0223
Plasmodium vivax calcium-transporting ATPase, putative 0.0009 0.0077 0.0091
Loa Loa (eye worm) fli-1 protein 0.0232 0.4876 0.4876
Loa Loa (eye worm) hypothetical protein 0.0009 0.0087 0.0087
Trichomonas vaginalis rotamase, putative 0.0035 0.0644 0.3129
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0009 0.0077 0.1368
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0244 0.0624
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0725 0.1955
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0217 0.4572 0.4572
Leishmania major hypothetical protein, conserved 0.0035 0.063 0.3044
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0177 0.0364
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0077 0.0322
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Echinococcus granulosus nibrin 0.001 0.0109 0.0265
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0109 0.0457
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0702 0.144
Trichomonas vaginalis abcb9, putative 0.0014 0.0183 0.0844
Entamoeba histolytica P-glycoprotein 5, putative 0.0014 0.0183 0.0899
Onchocerca volvulus Protein ultraspiracle homolog 0.0029 0.0505 0.0894
Schistosoma mansoni serine/threonine protein kinase 0.01 0.203 0.4162
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0249 0.355
Echinococcus granulosus ecdysone induced protein 78C 0.0029 0.0505 0.1351
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0177 0.0441
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0077 0.0166
Onchocerca volvulus 0.0254 0.5348 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0029 0.0505 0.0493
Loa Loa (eye worm) hypothetical protein 0.0038 0.0703 0.0703
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0124
Entamoeba histolytica hypothetical protein 0.0038 0.0702 0.3459
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0029 0.0505 0.1351
Loa Loa (eye worm) RecQ helicase 0.0025 0.043 0.043
Trichomonas vaginalis ABC transporter, putative 0.0014 0.0183 0.0844
Schistosoma mansoni hypothetical protein 0.0011 0.0124 0.0254
Entamoeba histolytica P-glycoprotein 6, putative 0.0006 0.0017 0.0083
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0109 0.0478
Echinococcus granulosus multidrug resistance associated protein 7 0.0006 0.0017 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0124
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0176 0.0869
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0014 0.0183 0.0325
Mycobacterium ulcerans beta-lactamase 0.0038 0.0703 1
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0007 0.0029 0.0034
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0077 0.0322
Schistosoma mansoni ras GTP exchange factor 0.0007 0.0029 0.006
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0017 0.0083
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0183 0.0844
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0124 0.0294
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0505 0.1035
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0142 0.0344
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0009 0.0077 0.1099
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0006 0.0017 0.0005
Loa Loa (eye worm) RasGEF domain-containing protein 0.0007 0.0029 0.0029
Brugia malayi hypothetical protein 0.0027 0.0458 0.0446
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0109 0.0097
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Echinococcus multilocularis ATP binding cassette sub family B 0.0014 0.0178 0.0442
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0087 0.0178
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0009 0.0077 0.0065
Brugia malayi hypothetical protein 0.0009 0.0087 0.0075
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0007 0.0029 0.0034
Trichomonas vaginalis ABC transporter, putative 0.0014 0.0183 0.0844
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0087 0.0178
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0077 0.038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.5107 1
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0009 0.0077 0.1099
Trypanosoma cruzi P-type H+-ATPase, putative 0.0009 0.0077 0.038
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0177 0.0364
Brugia malayi multidrug resistance protein 3 0.0014 0.0183 0.017
Schistosoma mansoni hypothetical protein 0.0012 0.0142 0.0291
Echinococcus multilocularis segment polarity protein dishevelled 0.0014 0.0179 0.0444
Trichomonas vaginalis ABC transporter, putative 0.0014 0.0183 0.0844
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0009 0.0077 0.0118
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0109 0.134
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.1529 0.4155
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0505 0.0493
Loa Loa (eye worm) DIX domain-containing protein 0.0014 0.0179 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0109 0.0478
Schistosoma mansoni ATPase 0.0009 0.0077 0.0158
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Brugia malayi hypothetical protein 0.0038 0.0702 0.0691
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0505 0.0493
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0109 0.0478
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0029 0.0505 0.134
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0014 0.0183 0.2598
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0029 0.0505 0.134
Loa Loa (eye worm) hypothetical protein 0.0007 0.0029 0.0029
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0725 0.3532
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0505 0.0493
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0087 0.0087
Schistosoma mansoni multidrug resistance protein 0.0035 0.063 0.1291
Treponema pallidum cation-transporting ATPase, P-type 0.0009 0.0077 0.7094
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0014 0.0183 0.0823
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0029 0.0505 0.0493
Schistosoma mansoni multidrug resistance protein 0.0006 0.0012 0.0025
Brugia malayi Pax transcription factor protein 2 0.0254 0.5348 0.5343
Echinococcus granulosus jun protein 0.0175 0.3656 1
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.1529 0.4162
Brugia malayi N-terminal motif family protein 0.0007 0.0029 0.0017
Loa Loa (eye worm) RasGEF domain-containing protein 0.0011 0.0121 0.0121
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.203 0.202
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.011 0.0269
Onchocerca volvulus 0.0038 0.0703 0.1266
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Echinococcus granulosus FTZ F1 alpha 0.0029 0.0505 0.1351
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0725 0.1945
Trypanosoma brucei P-type H+-ATPase, putative 0.0009 0.0077 0.03
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0077 0.038
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0124 0.0306
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0703 0.3462
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.0322
Brugia malayi hypothetical protein 0.0017 0.0255 0.0243
Brugia malayi ABC transporter family protein 0.0006 0.0017 0.0005
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Brugia malayi multidrug resistance related protein 1 0.0006 0.0017 0.0005
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0124 0.0294
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0015 0.0212 0.0436
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0009 0.0077 0.0322
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0244 0.1128
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0009 0.0077 0.0178
Schistosoma mansoni retinoic acid receptor RXR 0.0029 0.0505 0.1035
Toxoplasma gondii ABC transporter, putative 0.0006 0.0017 0.0241
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0007 0.0029 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0109
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0006 0.0017 0.0083
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.203 0.5536
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0009 0.0077 0.038
Brugia malayi beta-lactamase family protein 0.0038 0.0703 0.0691
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0177 0.0165
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0703 0.1347
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0.0109 0.9287
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0029 0.0505 0.1351
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0175 0.3656 1
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0032 0.0564 0.1504
Schistosoma mansoni ets 0.0011 0.0124 0.0254
Schistosoma mansoni kinase 0.0051 0.0975 0.2
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0009 0.0077 0.0879
Brugia malayi Steroid receptor seven-up type 2 0.0029 0.0505 0.0493
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0017 0.0241
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0009 0.0077 0.03
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0009 0.0077 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0029 0.0505 0.0493
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0177 0.0279
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.203 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0014 0.0183 0.0455
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0009 0.0077 0.03
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0109 0.2086
Echinococcus multilocularis protein C ets 2 0.0011 0.0124 0.0294
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0009 0.0077 0.0118
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0703 0.3407
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0212 0.02
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0176 0.0869
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.011 0.0486
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0009 0.0077 0.0879
Loa Loa (eye worm) hypothetical protein 0.0093 0.1886 0.1886
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0009 0.0077 0.0879
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0177 0.0165
Echinococcus granulosus expressed protein 0.0035 0.0644 0.1732
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0177 0.0453
Plasmodium vivax copper-transporting ATPase, putative 0.0009 0.0077 0.0091
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0183 0.0844
Giardia lamblia Replication factor C, subunit 1 0.001 0.0109 0.0478
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0458 1
Brugia malayi ABC transporter family protein 0.0014 0.0183 0.017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0212 0.0436
Schistosoma mansoni coup transcription factor 0.0029 0.0505 0.1035
Echinococcus granulosus ATP binding cassette sub family B 0.0006 0.0017 0.0013
Toxoplasma gondii hypothetical protein 0.0009 0.0087 0.1239
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0244 0.0244
Giardia lamblia ABC transporter, putative 0.0006 0.0017 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0029 0.0505 0.0505
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0009 0.0077 0.0879
Echinococcus multilocularis ras GTP exchange factor 0.0007 0.0029 0.0034
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0017 0.0083
Loa Loa (eye worm) pax transcription factor protein 2 0.0254 0.5348 0.5348
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0183 0.0467
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0177 0.0453
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0703 0.1884
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.038
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0029 0.0505 0.0894
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0177 0.0364
Toxoplasma gondii ABC transporter family protein 0.0006 0.0017 0.0241
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0056 0.0119
Brugia malayi photoreceptor-specific nuclear receptor 0.0029 0.0505 0.0493
Loa Loa (eye worm) hypothetical protein 0.0038 0.0703 0.0703
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0029 0.0505 0.0505
Brugia malayi Na,K-ATPase alpha subunit 0.0009 0.0077 0.0065
Schistosoma mansoni multidrug resistance protein 0.0014 0.0183 0.0374
Schistosoma mansoni ets-related 0.0232 0.4876 1
Brugia malayi N-terminal motif family protein 0.0007 0.0029 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0178 0.0178
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.0322
Trichomonas vaginalis rotamase, putative 0.0034 0.0626 0.3041
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0006 0.0017 0.0241
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0015 0.0212 0.0212
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0009 0.0077 0.0879
Brugia malayi DKFZp564C0469 protein 0.001 0.0109 0.0097
Schistosoma mansoni ets-related 0.0011 0.0124 0.0254
Echinococcus granulosus cation transporting ATPase 13A1 0.0009 0.0077 0.0178
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0007 0.0029 0.0083
Trypanosoma cruzi hypothetical protein 0.0007 0.0029 0.0144
Mycobacterium ulcerans lipase LipD 0.0038 0.0703 1
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0077 0.0166
Entamoeba histolytica P-glycoprotein 5, putative 0.0006 0.0012 0.0061
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0056 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0029 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0077
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0626 0.3083
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Schistosoma mansoni nuclear receptor 0.0014 0.0177 0.0364
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0035 0.063 0.1683
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0644 0.0632
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0029 0.0505 0.0493
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0244 0.0624
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0725 0.1955
Brugia malayi E1-E2 ATPase family protein 0.0009 0.0077 0.0065
Schistosoma mansoni multidrug resistance protein 0.0006 0.0017 0.0035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0029 0.0505 0.1035
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0014 0.0183 0.0183
Brugia malayi hypothetical protein 0.0093 0.1886 0.1876
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Entamoeba histolytica hypothetical protein 0.0038 0.0702 0.3459
Giardia lamblia Copper-transporting P-type ATPase 0.0009 0.0077 0.0322
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0244 0.1128
Trypanosoma cruzi proton motive ATPase 1, putative 0.0009 0.0077 0.038
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0109 0.1549
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0177 0.0165
Schistosoma mansoni dishevelled 0.0014 0.0179 0.0366
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0177 0.0279
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0087 0.0193
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0077 0.03
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0124 0.0306
Schistosoma mansoni zinc finger protein 0.0014 0.0177 0.0364
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0077 0.0166
Schistosoma mansoni RAR-like nuclear receptor 0.0029 0.0505 0.1035
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0109 0.0536
Brugia malayi nuclear hormone receptor 0.0014 0.0177 0.0165
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0725 0.3532
Echinococcus granulosus segment polarity protein dishevelled 0.0014 0.0179 0.0456
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.063 0.3102
Schistosoma mansoni smdr1 0.0006 0.0017 0.0035
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0316 0.0647
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0626 0.3025
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.011 0.0257
Brugia malayi steroid hormone receptor 0.0029 0.0505 0.0493
Plasmodium falciparum copper-transporting ATPase 0.0009 0.0077 0.1368
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0177 0.0441
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0458 0.2189
Schistosoma mansoni multidrug resistance protein 0.0014 0.0183 0.0374
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0124 0.0124
Brugia malayi hypothetical protein 0.001 0.0109 0.0097
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0725 0.3571
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0109 0.0223
Schistosoma mansoni dep domain containing protein 0.0009 0.0087 0.0178
Schistosoma mansoni hypothetical protein 0.0038 0.0702 0.144
Brugia malayi hypothetical protein 0.001 0.0109 0.0097
Loa Loa (eye worm) ABC transporter 0.0006 0.0017 0.0017
Brugia malayi Fli-1 protein 0.0232 0.4876 0.487
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0009 0.0077 0.0322
Schistosoma mansoni thyroid hormone receptor 0.0029 0.0505 0.1035
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Giardia lamblia Multidrug resistance-associated protein 1 0.0006 0.0017 0.0023
Schistosoma mansoni atpase class VI type 11c 0.0009 0.0077 0.0158
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0087 0.0193
Brugia malayi ecdysteroid receptor 0.0029 0.0505 0.0493
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0014 0.0183 0.0467
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0006 0.0017 0.0083
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0009 0.0077 0.038
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0244 0.1128
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0009 0.0077 0.0065
Schistosoma mansoni dishevelled 0.0014 0.0179 0.0366
Brugia malayi Ets-domain containing protein 0.0076 0.1529 0.1519
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Brugia malayi nuclear hormone receptor 0.0029 0.0505 0.0493
Schistosoma mansoni DNA helicase recq5 0.001 0.011 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0109 0.0478
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Mycobacterium ulcerans hypothetical protein 0.0038 0.0703 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0029 0.0505 0.0505
Brugia malayi P-glycoprotein-like protein 0.0006 0.0017 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0505 0.134
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.203 0.203
Plasmodium falciparum multidrug resistance protein 1 0.0014 0.0183 0.3759
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0109 0.0478
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0626 0.3083
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0077 0.0166
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0244 0.0341
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0176 0.0814
Schistosoma mansoni nuclear receptor 0.0014 0.0177 0.0364
Trichomonas vaginalis ras GTP exchange factor, putative 0.0007 0.0029 0.0083
Brugia malayi hypothetical protein 0.0006 0.0017 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0244 0.0624
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0015 0.0212 0.0549
Brugia malayi isocitrate dehydrogenase 0.0017 0.0244 0.0232
Schistosoma mansoni multidrug resistance protein 0.0006 0.0017 0.0035
Schistosoma mansoni multidrug resistance protein 0.0006 0.0017 0.0035
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0029 0.0505 0.1035
Loa Loa (eye worm) calcium ATPase 0.0009 0.0077 0.0077
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0124 0.0124
Entamoeba histolytica P-glycoprotein-1 0.0014 0.0183 0.0899
Loa Loa (eye worm) hypothetical protein 0.0014 0.0183 0.0183
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0017 0.0241
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0009 0.0077 0.0322
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0116 0.0571
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0009 0.0077 0.038
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.203 1
Trichomonas vaginalis abcb9, putative 0.0014 0.0183 0.0844
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0009 0.0077 0.0166
Entamoeba histolytica P-glycoprotein-2, putative 0.0006 0.0012 0.0061
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0014 0.0183 0.0455
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0014 0.0183 0.0455
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0014 0.0183 0.2598
Onchocerca volvulus 0.0014 0.0183 0.0288
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0009 0.0077 0.0322
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0009 0.0077 0.0077
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0505 0.0493
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Schistosoma mansoni jun-related protein 0.0142 0.295 0.605
Leishmania major hypothetical protein, conserved 0.0027 0.0458 0.2189
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0077 0.0166
Trichomonas vaginalis ras GTP exchange factor, putative 0.0007 0.0029 0.0083
Entamoeba histolytica hypothetical protein 0.0038 0.0702 0.3459
Schistosoma mansoni cation-transporting atpase worm 0.0009 0.0077 0.0158
Treponema pallidum DNA ligase (lig) 0.001 0.0109 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0725 0.3532
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Echinococcus multilocularis cation transporting atpase worm 0.0009 0.0077 0.0166
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Echinococcus multilocularis ets variant gene 4 0.0011 0.0124 0.0294
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0009 0.0077 0.0178
Loa Loa (eye worm) multidrug resistance protein 3 0.0014 0.0183 0.0183
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0703 0.3422
Trypanosoma brucei MATE efflux family protein, putative 0.0035 0.063 0.3044
Brugia malayi nuclear receptor RXR 0.0014 0.0177 0.0165
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0124 0.0294
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0244 0.0232
Brugia malayi Ets-domain containing protein 0.0011 0.0124 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0077 0.038
Schistosoma mansoni multidrug resistance protein 0.0014 0.0183 0.0374
Trypanosoma cruzi hypothetical protein 0.0007 0.0029 0.0144
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Leishmania major p-glycoprotein 0.0014 0.0183 0.0823
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0458 0.2254
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0087 0.0205
Onchocerca volvulus 0.0038 0.0703 0.1266
Trypanosoma brucei cation-transporting ATPase, putative 0.0009 0.0077 0.03
Loa Loa (eye worm) hypothetical protein 0.0038 0.0703 0.0703
Entamoeba histolytica P-glycoprotein-2 0.0014 0.0183 0.0899
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0077 0.038
Schistosoma mansoni multidrug resistance protein 0.0006 0.0017 0.0035
Schistosoma mansoni copper ABC transporter ATPase 0.0009 0.0077 0.0158
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0124 0.0124
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0014 0.0179 0.0281
Loa Loa (eye worm) beta-lactamase 0.0038 0.0703 0.0703
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0183 0.0467
Brugia malayi RasGEF domain containing protein 0.0011 0.0121 0.0108
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0702 0.1882
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0035 0.063 0.1694
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0007 0.0029 0.0144
Entamoeba histolytica P-glycoprotein-5 0.0014 0.0183 0.0899
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0009 0.0077 0.038
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0109
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0014 0.0183 1
Entamoeba histolytica P-glycoprotein 6, putative 0.0006 0.0017 0.0083
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0017 0.0241
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0703 1
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0087 0.0075
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0183 0.0844
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0017
Echinococcus granulosus ras GTP exchange factor 0.0007 0.0029 0.0046
Echinococcus multilocularis multidrug resistance protein 1 0.0014 0.0183 0.0455
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0703 0.1347
Loa Loa (eye worm) hypothetical protein 0.0038 0.0703 0.0703
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0505 0.0493
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0725 0.3517
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0703 0.1441
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0109 0.0536
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.011 0.157
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0009 0.0077 0.0879
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0505 0.0493
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0505 0.134
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0725 0.1486
Echinococcus granulosus multidrug resistance associated protein 1 0.0006 0.0017 0.0013
Brugia malayi hypothetical protein 0.0015 0.0212 0.02
Schistosoma mansoni ATPase 0.0009 0.0077 0.0158
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0124 0.0306
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0029 0.0505 0.1351
Brugia malayi nuclear receptor RXR 0.0015 0.0212 0.02
Leishmania major calcium-translocating P-type ATPase 0.0009 0.0077 0.03
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0007 0.0029 0.0046
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0008 0.0056 0.0214
Loa Loa (eye worm) hypothetical protein 0.0015 0.0212 0.0212
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0183 0.0467
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0009 0.0077 0.0322
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0177 0.0165
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0458 0.0662
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0725 0.1955
Loa Loa (eye worm) hypothetical protein 0.0027 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0015 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0177 0.0165
Schistosoma mansoni elf1 0.0011 0.0124 0.0254
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0109 0.0536
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0644 0.3129
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0006 0.0017 0.0083
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0177 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0947 0.4632
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0077 0.038
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0077 0.0166
Echinococcus granulosus ATP binding cassette sub family B 0.0006 0.0017 0.0013
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0177 0.0453
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0109 0.134
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0244 0.0636
Entamoeba histolytica P-glycoprotein-2, putative 0.0014 0.0183 0.0899
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.063 0.3102
Echinococcus multilocularis jun protein 0.0175 0.3656 1
Schistosoma mansoni DNA helicase recq1 0.001 0.011 0.0226
Brugia malayi beta-lactamase family protein 0.0038 0.0703 0.0691
Brugia malayi beta-lactamase 0.0038 0.0703 0.0691
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0244 0.0624
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0244 0.0446
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0012
Trypanosoma brucei membrane transporter protein, putative 0.0035 0.063 0.3044
Leishmania major hypothetical protein, conserved 0.0038 0.0703 0.3407
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0505 0.1351
Brugia malayi hypothetical protein 0.0009 0.0087 0.0075
Brugia malayi ABC transporter transmembrane region family protein 0.0006 0.0017 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0505 0.0493
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0077 0.0322
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0124 0.0294
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0014 0.0178 0.0455
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0014 0.0183 0.0455
Brugia malayi ecdysone receptor 0.0014 0.0177 0.0165
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0116 0.1649
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0009 0.0077 0.038
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0142 0.0356
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0009 0.0077 0.0158
Echinococcus multilocularis FTZ F1 alpha 0.0029 0.0505 0.134
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0109
Toxoplasma gondii P-type ATPase PMA1 0.0009 0.0077 0.1099
Echinococcus multilocularis nibrin 0.001 0.0109 0.0253
Brugia malayi RasGEF domain containing protein 0.0007 0.0029 0.0017
Brugia malayi nuclear receptor NHR-88 0.0014 0.0177 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0109 0.0478
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0007 0.0029 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0029 0.0505 0.0505
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0087 0.0075
Giardia lamblia Kinase, PLK 0.01 0.203 1
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0009 0.0077 0.0065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Mycobacterium leprae Probable lipase LipE 0.0038 0.0703 1
Brugia malayi ABC transporter family protein 0.0006 0.0017 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0505 0.1035
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.063 0.3102
Brugia malayi ABC transporter family protein 0.0006 0.0017 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0703 0.3422
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0077 0.03
Trypanosoma brucei membrane transporter protein, putative 0.0035 0.063 0.3044
Echinococcus multilocularis son of sevenless 1 0.0007 0.0029 0.0034
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0006 0.0017 0.0023
Plasmodium vivax multidrug resistance protein 1, putative 0.0014 0.0183 0.0249
Loa Loa (eye worm) hypothetical protein 0.0039 0.0725 0.0725
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0703 0.0703
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0077 0.038
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0124 0.0294
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Brugia malayi conserved hypotetical protein 0.0014 0.0177 0.0165
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0109 0.1549
Schistosoma mansoni DNA ligase IV 0.001 0.0109 0.0223
Brugia malayi bZIP transcription factor family protein 0.0175 0.3656 0.3649
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0017 0.0241
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0006 0.0022 0.0045
Onchocerca volvulus 0.0014 0.0177 0.0279
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0244 0.3472
Trypanosoma cruzi cation-transporting ATPase, putative 0.0009 0.0077 0.038
Loa Loa (eye worm) hypothetical protein 0.0007 0.0029 0.0029
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0006 0.0017 0.0017
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0077 0.038
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0077 0.038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0077
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0947 0.4632
Brugia malayi hypothetical protein 0.0014 0.0177 0.0165
Plasmodium vivax P-type ATPase4, putative 0.0009 0.0077 0.0091
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0009 0.0077 0.0322
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0029 0.0505 0.1035
Loa Loa (eye worm) hypothetical protein 0.001 0.011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0725 0.3532
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0009 0.0077 0.03
Loa Loa (eye worm) hypothetical protein 0.0014 0.0179 0.0179
Schistosoma mansoni cation-transporting atpase worm 0.0009 0.0077 0.0158
Trypanosoma brucei polo-like protein kinase 0.01 0.203 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0364 0.7879
Entamoeba histolytica P-glycoprotein-2 0.0014 0.0183 0.0899
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0087 0.0193
Brugia malayi transcription factor E74 isoform 0.0011 0.0124 0.0112
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0458 0.2254
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0109 0.0478
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0725 0.3571
Schistosoma mansoni eyes absent homolog 0.0093 0.1886 0.3867
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0029 0.0505 0.1351
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0087 0.0178
Loa Loa (eye worm) hypothetical protein 0.0009 0.0087 0.0087
Echinococcus granulosus Protein son of sevenless 0.0007 0.0029 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0109 0.0478
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0017
Brugia malayi DIX domain containing protein 0.0014 0.0179 0.0166
Loa Loa (eye worm) DR-78 0.0014 0.0177 0.0177
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.043 0.0418
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0244 0.1202
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0116 0.0492
Echinococcus granulosus cation transporting ATPase 13A3 0.0009 0.0077 0.0178
Echinococcus multilocularis multidrug resistance protein 1 0.0008 0.0056 0.0106
Echinococcus multilocularis segment polarity protein dishevelled 0.0014 0.0179 0.0444
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0725 0.1945
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0009 0.0077 0.0118
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0703 0.1894
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0077
Loa Loa (eye worm) ABC transporter 0.0006 0.0017 0.0017
Plasmodium vivax cation transporting ATPase, putative 0.0009 0.0077 0.0091
Echinococcus multilocularis expressed protein 0.0035 0.0644 0.1722
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.043 0.2072
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0244 0.3472
Onchocerca volvulus Bile acid receptor homolog 0.0029 0.0505 0.0894
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0177 0.0441
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0009 0.0077 0.0065
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0014 0.0183 0.0455
Entamoeba histolytica hypothetical protein 0.0006 0.0017 0.0083
Brugia malayi nuclear receptor NHR-67 0.0014 0.0177 0.0165
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.203 0.553
Echinococcus multilocularis Protein son of sevenless 0.0007 0.0029 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0029 0.0505 0.0493
Schistosoma mansoni hypothetical protein 0.0011 0.0124 0.0254
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0077
Schistosoma mansoni thyroid hormone receptor 0.0029 0.0505 0.1035
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.203 1
Toxoplasma gondii ABC1 family protein 0.0038 0.0703 1
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0009 0.0077 0.0879
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0029 0.0505 0.134
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0458 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0183 0.0183
Echinococcus granulosus segment polarity protein dishevelled 0.0014 0.0179 0.0456
Entamoeba histolytica hypothetical protein 0.0038 0.0702 0.3459
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0029 0.0505 0.1351
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0177 0.0453
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0014 0.0179 0.0166
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0029 0.0505 0.1035
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0007 0.0029 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0029 0.0505 0.0505
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0009 0.0077 0.1099
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0014 0.0183 0.0844
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0009 0.0077 0.0118
Echinococcus granulosus protein C ets 2 0.0011 0.0124 0.0306
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0009 0.0077 0.1099
Trichomonas vaginalis ABC transporter, putative 0.0014 0.0183 0.0844
Schistosoma mansoni steroid hormone receptor ad4bp 0.0029 0.0505 0.1035
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Giardia lamblia Multidrug resistance-associated protein 1 0.0006 0.0017 0.0023
Echinococcus granulosus replication factor c subunit 1 0.001 0.0109 0.0265
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0017 0.0241
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0175 0.3656 1
Schistosoma mansoni hypothetical protein 0.0142 0.295 0.605
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0009 0.0077 0.0879
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0009 0.0077 0.0158
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0083
Loa Loa (eye worm) hypothetical protein 0.0065 0.1291 0.1291
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0703 1
Brugia malayi nuclear receptor NHR-88 0.0029 0.0505 0.0493
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0626 0.3025
Loa Loa (eye worm) hypothetical protein 0.019 0.3983 0.3983
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.011 0.0098
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.011 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.063 0.3102
Schistosoma mansoni smdr2 0.0014 0.0183 0.0374
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0087 0.0205
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.011 0.0098
Echinococcus granulosus cation transporting atpase worm 0.0009 0.0077 0.0178
Echinococcus multilocularis ecdysone induced protein 78C 0.0029 0.0505 0.134
Entamoeba histolytica ATP-binding cassette protein, putative 0.0006 0.0017 0.0083
Trichomonas vaginalis abcb9, putative 0.0014 0.0183 0.0844
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0029 0.0505 0.1035
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0077 0.0166
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Echinococcus multilocularis cation transporting ATPase 13A1 0.0009 0.0077 0.0166
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Loa Loa (eye worm) hypothetical protein 0.0127 0.2628 0.2628
Onchocerca volvulus 0.0014 0.0177 0.0279
Brugia malayi N-terminal motif family protein 0.019 0.3983 0.3976
Onchocerca volvulus 0.001 0.0109 0.015
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0703 0.3422
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0244 0.1202
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0014 0.0183 0.0844
Brugia malayi hypothetical protein 0.0015 0.0212 0.02
Trypanosoma cruzi membrane transporter protein, putative 0.0035 0.063 0.3102
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0703 0.1347
Leishmania major hypothetical protein, conserved 0.0035 0.063 0.3044
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0116 0.0492
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0703 0.3422
Loa Loa (eye worm) RasGEF domain-containing protein 0.0007 0.0029 0.0029
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0006 0.0017 0.0241
Brugia malayi hypothetical protein 0.0014 0.0177 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0703 0.3462
Echinococcus multilocularis bloom syndrome protein 0.0025 0.043 0.1136
Mycobacterium tuberculosis Conserved protein 0.0038 0.0703 0.1347
Loa Loa (eye worm) gopc protein 0.0469 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0505 0.0505
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0006 0.0017 0.0083
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0702 0.1893
Loa Loa (eye worm) hypothetical protein 0.0038 0.0703 0.0703
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0109 0.0536
Echinococcus multilocularis copper transporting ATPase 1 0.0009 0.0077 0.0166
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.011 0.2119
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0029 0.0505 0.134
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0177 0.0177
Mycobacterium tuberculosis Conserved protein 0.0038 0.0703 0.1347
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0212 0.02
Leishmania major proton motive ATPase, putative 0.0009 0.0077 0.03
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0177
Toxoplasma gondii P-type ATPase4, putative 0.0009 0.0077 0.1099
Leishmania major P-type H -ATPase, putative 0.0009 0.0077 0.03
Loa Loa (eye worm) hypothetical protein 0.017 0.3553 0.3553
Echinococcus granulosus phospholipid transporting ATPase VA 0.0009 0.0077 0.0178
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0077 0.0178
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0177 0.0441
Trichomonas vaginalis esterase, putative 0.0038 0.0703 0.3422
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0009 0.0077 0.0118
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0124 0.0306
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0124 0.0294
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0007 0.0029 0.0144
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0725 0.1486
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0009 0.0077 0.03
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0626 0.8905
Trypanosoma brucei P-type H+-ATPase, putative 0.0009 0.0077 0.03
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Loa Loa (eye worm) ABC transporter 0.0006 0.0017 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.01 0.203 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0029 0.0505 0.134
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0087 0.0205
Brugia malayi ABC transporter 0.0006 0.0017 0.0005
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.3983 0.7433
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0007 0.0029 0.006
Echinococcus multilocularis multidrug resistance protein 1 0.0014 0.0183 0.0455
Brugia malayi tailless protein 0.0014 0.0177 0.0165
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0009 0.0077 0.1099
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0109 0.0097
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0177 0.0441
Leishmania major P-type H -ATPase, putative 0.0009 0.0077 0.03
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.011 0.0257
Onchocerca volvulus 0.0038 0.0703 0.1266
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.203 0.3761
Echinococcus granulosus son of sevenless 1 0.0007 0.0029 0.0046
Brugia malayi hypothetical protein 0.0009 0.0077 0.0065
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0015 0.0212 0.0537
Brugia malayi E1-E2 ATPase family protein 0.0009 0.0077 0.0065
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0009 0.0077 0.1099
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0703 0.1441
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0124 0.0124
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0315 0.6672 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0725 0.3571
Echinococcus granulosus copper transporting ATPase 1 0.0009 0.0077 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0109 0.0478
Schistosoma mansoni multidrug resistance protein 0.0006 0.0017 0.0035
Schistosoma mansoni phosphoserine phosphatase 0.0009 0.0077 0.0158
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0109 0.0253
Schistosoma mansoni topbp1 0.001 0.0109 0.0223
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0029 0.0505 0.0505
Brugia malayi Patched family protein 0.0217 0.4572 0.4565
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0124 0.0306
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0177 0.0177
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0014 0.0183 0.0467
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0029 0.0505 0.0493
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0014 0.0183 0.0844
Entamoeba histolytica P-glyco protein 6, putative 0.0014 0.0183 0.0899
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0703 0.1347
Brugia malayi topoisomerase 0.001 0.0109 0.0097
Loa Loa (eye worm) E1-E2 ATPase 0.0009 0.0077 0.0077
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0109 0.0138
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0124 0.0112
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0014 0.0183 0.0467
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0725 0.0713
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0077 0.0322
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0011 0.0116 1
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0124 0.0254
Loa Loa (eye worm) hypothetical protein 0.0015 0.0212 0.0212
Entamoeba histolytica multidrug resistance protein, putative 0.0006 0.0017 0.0083
Onchocerca volvulus 0.0029 0.0505 0.0894
Trichomonas vaginalis taga, putative 0.0014 0.0183 0.0844
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0703 0.1347
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.1529 0.1529
Treponema pallidum hypothetical protein 0.0009 0.0077 0.7094
Giardia lamblia MRP-like ABC transporter 0.0006 0.0017 0.0023
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0177 0.0453

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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