Detailed information for compound 827680

Basic information

Technical information
  • TDR Targets ID: 827680
  • Name: N-(2-carbamoylphenyl)-8-methyl-4-oxothieno[4, 5-c]chromene-2-carboxamide
  • MW: 378.401 | Formula: C20H14N2O4S
  • H donors: 2 H acceptors: 3 LogP: 3.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)c1sc(cc1c(=O)o2)C(=O)Nc1ccccc1C(=O)N
  • InChi: 1S/C20H14N2O4S/c1-10-6-7-15-12(8-10)17-13(20(25)26-15)9-16(27-17)19(24)22-14-5-3-2-4-11(14)18(21)23/h2-9H,1H3,(H2,21,23)(H,22,24)
  • InChiKey: NGWFMLABDGFWCJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-carbamoylphenyl)-8-methyl-4-oxo-thieno[4,5-c]chromene-2-carboxamide
  • N-(2-carbamoylphenyl)-8-methyl-4-oxo-2-thieno[4,5-c]chromenecarboxamide
  • N-(2-carbamoylphenyl)-4-keto-8-methyl-thieno[4,5-c]chromene-2-carboxamide
  • N-(2-aminocarbonylphenyl)-8-methyl-4-oxo-thieno[4,5-c]chromene-2-carboxamide
  • C593-1289
  • NCGC00110611-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.012 0.0188
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0025 0.0062
Echinococcus granulosus son of sevenless 1 0.0013 0.0008 0.0008
Echinococcus multilocularis musashi 0.0028 0.0115 0.0115
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0025 0.0079
Plasmodium falciparum DNA repair protein REV1, putative 0.0029 0.0124 0.0513
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0007 0.0016
Schistosoma mansoni rotamase 0.0034 0.0163 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0262 0.0411
Brugia malayi polk-prov protein 0.0056 0.0321 0.0819
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Onchocerca volvulus 0.0028 0.0115 0.0338
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0032 0.013
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0033 0.0084
Schistosoma mansoni sugar transporter 0.0015 0.0025 0.0024
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0033 0.0137
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0033 0.0137
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0033 0.0137
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0025 0.0062
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0467 0.1944
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0032 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Echinococcus granulosus chromobox protein 1 0.0071 0.0432 0.0432
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0001 0.0001
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0256 0.0653
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0008 0.0019
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0115 0.0294
Brugia malayi hypothetical protein 0.0015 0.0025 0.0062
Echinococcus granulosus lamin dm0 0.0028 0.0115 0.0115
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0025 0.0025
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Leishmania major glucose transporter/membrane transporter D2, putative 0.0015 0.0025 0.0101
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0007 0.0025
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.2154 0.8965
Echinococcus granulosus leucyl aminopeptidase 0.0022 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0144 0.0959 0.2452
Brugia malayi Cytochrome P450 family protein 0.0013 0.0007 0.0016
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0784 0.2004
Trypanosoma cruzi DNA polymerase eta, putative 0.0144 0.0959 0.399
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Brugia malayi hypothetical protein 0.0018 0.0045 0.0115
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0025 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0427 0.1777
Brugia malayi regulator of G-protein signaling egl-10 0.0018 0.0045 0.0115
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0064 0.0263
Brugia malayi Pre-SET motif family protein 0.0421 0.2957 0.7561
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0344 0.2403 0.784
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0033 0.0137
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.002
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0008 0.0012
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0069 0.0108
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0064 0.0206
Onchocerca volvulus 0.0015 0.0025 0.0073
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0033 0.0137
Plasmodium vivax glutathione reductase, putative 0.0047 0.0256 0.1063
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0432 0.0678
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0124 0.0513
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0616 0.0616
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0405 0.1683
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0351 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0321 0.1334
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0025 0.0062
Echinococcus granulosus geminin 0.0174 0.1171 0.1171
Brugia malayi hypothetical protein 0.0018 0.0045 0.0115
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0064 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0124 0.0513
Entamoeba histolytica phosphoglycerate kinase, putative 0.0344 0.2403 0.3776
Echinococcus multilocularis microtubule associated protein 2 0.1395 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0033 0.0052
Schistosoma mansoni lipoxygenase 0.0121 0.0793 0.0793
Onchocerca volvulus 0.0012 0.0001 0.0002
Plasmodium falciparum glutathione reductase 0.0047 0.0256 0.1063
Brugia malayi major facilitator superfamily protein 0.0015 0.0025 0.0062
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.0753
Trypanosoma brucei sugar transporter, putative 0.0015 0.0025 0.0101
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0154 0.05
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0029 0.0124 0.0513
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0013 0.0008 0.0031
Loa Loa (eye worm) glutaminase 0.0552 0.391 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.012 0.0782 0.0782
Brugia malayi Pre-SET motif family protein 0.006 0.0352 0.0898
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0115
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0025 0.0101
Mycobacterium ulcerans epimerase 0.002 0.0061 0.0154
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0033 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Brugia malayi hypothetical protein 0.0015 0.0025 0.0062
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0351 0.0351
Plasmodium vivax phosphoglycerate kinase, putative 0.0344 0.2403 1
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Schistosoma mansoni hypothetical protein 0.0174 0.1171 0.1171
Echinococcus granulosus phosphoglycerate kinase 1 0.0344 0.2403 0.2403
Echinococcus granulosus Protein son of sevenless 0.0013 0.0008 0.0008
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.2154 0.8965
Onchocerca volvulus 0.0072 0.0436 0.128
Echinococcus granulosus solute carrier family 22 0.0015 0.0025 0.0025
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) runx1 0.0061 0.0354 0.0903
Echinococcus granulosus leucine aminopeptidase protein 0.0108 0.0698 0.0698
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0227 0.0356
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0124 0.0513
Onchocerca volvulus 0.002 0.0062 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0636 0.2644
Onchocerca volvulus 0.0012 0.0001 0.0002
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0366 0.0366
Echinococcus granulosus dna polymerase kappa 0.012 0.0784 0.0784
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0616 0.1806
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.008
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0344 0.2403 1
Trypanosoma brucei unspecified product 0.0064 0.0378 0.1573
Brugia malayi Heterochromatin protein 1 0.0071 0.0432 0.1103
Trypanosoma brucei trypanothione reductase 0.0047 0.0256 0.1063
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0008 0.0007
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0045 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0256 0.0834
Trichomonas vaginalis DNA polymerase eta, putative 0.012 0.0784 0.1232
Brugia malayi jmjC domain containing protein 0.0016 0.0032 0.008
Onchocerca volvulus 0.0015 0.0025 0.0073
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0036 0.0173 0.0717
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0344 0.2403 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0784 0.3261
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0115 0.0294
Brugia malayi MH2 domain containing protein 0.0119 0.0775 0.1981
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0126 0.0828 0.3447
Schistosoma mansoni DNA polymerase eta 0.0144 0.0959 0.0959
Brugia malayi glutaminase DH11.1 0.0552 0.391 1
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Onchocerca volvulus 0.002 0.0062 0.0182
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0001 0.0001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.01 0.0636 0.2644
Echinococcus multilocularis muscleblind protein 0.0153 0.1023 0.1023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Onchocerca volvulus 0.0012 0.0001 0.0002
Leishmania major hypothetical protein, conserved 0.0015 0.0025 0.0101
Loa Loa (eye worm) hypothetical protein 0.0483 0.3409 0.8717
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0045 0.0133
Plasmodium vivax SET domain protein, putative 0.006 0.0352 0.1462
Echinococcus multilocularis dna polymerase kappa 0.012 0.0784 0.0784
Echinococcus granulosus ras GTP exchange factor 0.0013 0.0008 0.0008
Schistosoma mansoni kinase 0.0049 0.0271 0.0271
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0205 0.0321
Mycobacterium ulcerans leucyl aminopeptidase 0.0108 0.0698 0.1783
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.012 0.0188
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0405 0.0635
Schistosoma mansoni glucose transport protein 0.0015 0.0025 0.0024
Schistosoma mansoni lamin 0.0028 0.0115 0.0115
Brugia malayi Muscleblind-like protein 0.0153 0.1023 0.2614
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0045 0.0115
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0008 0.0019
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0022 0.0071 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0022 0.0071 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Schistosoma mansoni microtubule-associated protein tau 0.1395 1 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0033 0.0108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0033 0.0137
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0344 0.2403 0.3776
Giardia lamblia DNA damage repair protein 0.0029 0.0124 0.0194
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.006 0.0352 0.0898
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0032 0.013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0013 0.0008 0.0012
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0013 0.0008 0.0008
Echinococcus multilocularis chromobox protein 1 0.0071 0.0432 0.0432
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0032 0.008
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0435 0.3064 0.7836
Giardia lamblia Hexose transporter 0.0015 0.0025 0.0038
Onchocerca volvulus Putative transporter 0.0015 0.0025 0.0073
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0199 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0427 0.1777
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0033 0.0033
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0001 0.0001
Loa Loa (eye worm) doublecortin family protein 0.002 0.0062 0.0158
Brugia malayi RasGEF domain containing protein 0.0013 0.0008 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0784 0.3261
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0025 0.0025
Schistosoma mansoni z-protein (S1r protein) 0.0018 0.0045 0.0045
Schistosoma mansoni terminal deoxycytidyl transferase 0.0093 0.0587 0.0586
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0025 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0321 0.1334
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0366 0.0934
Onchocerca volvulus 0.0015 0.0025 0.0073
Plasmodium vivax sugar transporter, putative 0.0015 0.0025 0.0101
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0032 0.0032
Echinococcus multilocularis oxidoreductase 0.0012 0.0001 0.0001
Trypanosoma cruzi hypothetical protein 0.0013 0.0008 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0033 0.0084
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0032 0.013
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.0113 0.0735 0.3058
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0405 0.1683
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Schistosoma mansoni sugar transporter 0.0015 0.0025 0.0024
Echinococcus granulosus oxidoreductase 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Echinococcus multilocularis lamin 0.0028 0.0115 0.0115
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0062 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0064 0.0064
Echinococcus granulosus muscleblind protein 0.0153 0.1023 0.1023
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0352 0.0352
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0032 0.0032
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.005 0.0208
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0108 0.0698 0.2902
Onchocerca volvulus 0.0012 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0181 0.0753
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0032 0.008
Leishmania major DNA polymerase kappa, putative 0.0029 0.0124 0.0513
Echinococcus multilocularis Protein son of sevenless 0.0013 0.0008 0.0008
Onchocerca volvulus 0.0015 0.0025 0.0073
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0033 0.0137
Giardia lamblia DINP protein human, muc B family 0.01 0.0636 0.0999
Echinococcus granulosus intermediate filament protein 0.0028 0.0115 0.0115
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.01 0.0636 0.2073
Brugia malayi hypothetical protein 0.002 0.0062 0.0158
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0033 0.0137
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.2154 0.8965
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Trypanosoma brucei phosphoglycerate kinase 0.0344 0.2403 1
Chlamydia trachomatis cytosol aminopeptidase 0.0108 0.0698 0.2804
Loa Loa (eye worm) hypothetical protein 0.0344 0.2403 0.6144
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0975 0.4056
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.0753
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0124 0.0513
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0093 0.0587 0.0587
Brugia malayi Cytochrome P450 family protein 0.0013 0.0007 0.0016
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0351 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.023 0.0956
Trypanosoma brucei DNA polymerase eta, putative 0.0144 0.0959 0.399
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0108 0.0698 0.2275
Echinococcus granulosus solute carrier family 22 0.0015 0.0025 0.0025
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0069 0.0175
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0616 0.1573
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0352 0.0351
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0154 0.05
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0142 0.0363
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0163 0.1095 0.2798
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.1095 0.3571
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.023 0.0956
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0012 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0483 0.3409 0.8717
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0975 0.4056
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0033 0.0137
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0181 0.0284
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0784 0.3261
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Brugia malayi chromobox protein homolog 3 0.004 0.0205 0.0523
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0025 0.0101
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Schistosoma mansoni ras GTP exchange factor 0.0013 0.0008 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Loa Loa (eye worm) hypothetical protein 0.0153 0.1023 0.2614
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0025 0.0038
Giardia lamblia Kinase, PLK 0.0097 0.0616 0.0967
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0025 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0351 0.0897
Echinococcus multilocularis solute carrier family 22 0.0015 0.0025 0.0025
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.012 0.0782 0.2552
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0025 0.0062
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0692 0.2258
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0616 0.2561
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0256 0.1063
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0025 0.0079
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0405 0.0405
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0405 0.1034
Schistosoma mansoni hypothetical protein 0.0048 0.0263 0.0262
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0025 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0262 0.0411
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Echinococcus multilocularis geminin 0.0174 0.1171 0.1171
Trichomonas vaginalis set domain proteins, putative 0.0479 0.3377 0.5308
Brugia malayi jmjC domain containing protein 0.0016 0.0032 0.008
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0108 0.0698 0.2902
Trypanosoma brucei THT1 - hexose transporter, putative 0.0015 0.0025 0.0101
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0022 0.0071 0.0071
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0033 0.0137
Onchocerca volvulus 0.0012 0.0001 0.0002
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0001 0.0001
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Brugia malayi Sugar transporter family protein 0.0015 0.0025 0.0062
Schistosoma mansoni glucose transport protein 0.0015 0.0025 0.0024
Loa Loa (eye worm) glutaminase 2 0.0552 0.391 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0015 0.0025 0.0101
Chlamydia trachomatis endonuclease IV 0.0076 0.0467 0.1832
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0032 0.0031
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0045 0.0045
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0013 0.0008 0.0024
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0033 0.0084
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0001 0.0001
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0108 0.0698 0.2902
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0427 0.1777
Loa Loa (eye worm) sugar transporter 0.0015 0.0025 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus multilocularis son of sevenless 1 0.0013 0.0008 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0181 0.0284
Schistosoma mansoni dishevelled 0.0018 0.0045 0.0045
Schistosoma mansoni lipoxygenase 0.0085 0.0529 0.0528
Brugia malayi intermediate filament protein 0.0028 0.0115 0.0294
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0692 0.2258
Toxoplasma gondii endonuclease IV APN 0.0076 0.0467 0.1944
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0069 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0062 0.0062
Brugia malayi ImpB/MucB/SamB family protein 0.0144 0.0959 0.2452
Schistosoma mansoni phosphoglycerate kinase 0.0344 0.2403 0.2402
Entamoeba histolytica hypothetical protein 0.0013 0.0008 0.0012
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0013 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Onchocerca volvulus 0.0028 0.0115 0.0338
Schistosoma mansoni jumonji domain containing protein 0.006 0.0351 0.0351
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0435 0.3064 1
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0045 0.0115
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0064 0.0162
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0032 0.0031
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0025 0.0024
Brugia malayi SET domain containing protein 0.0014 0.0016 0.004
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Toxoplasma gondii exonuclease III APE 0.0021 0.0064 0.0263
Onchocerca volvulus 0.0015 0.0025 0.0073
Brugia malayi N-terminal motif family protein 0.0365 0.2554 0.653
Loa Loa (eye worm) RecQ helicase 0.0021 0.0069 0.0175
Trypanosoma brucei THT1 - hexose transporter, putative 0.0015 0.0025 0.0101
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0045 0.0045
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0023 0.0056
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0064 0.0263
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0344 0.2403 0.784
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0124 0.0513
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0181 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.0784 0.3261
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Schistosoma mansoni polycystin 1-related 0.002 0.0062 0.0062
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0891 0.6361 1
Echinococcus granulosus chromobox protein 1 0.0071 0.0432 0.0432
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0045 0.0045
Onchocerca volvulus 0.0012 0.0001 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0891 0.6361 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0157 0.0652
Mycobacterium ulcerans hypothetical protein 0.0029 0.0124 0.0315
Brugia malayi major facilitator superfamily protein 0.0015 0.0025 0.0062
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Onchocerca volvulus 0.0012 0.0001 0.0002
Brugia malayi N-terminal motif family protein 0.0013 0.0008 0.0019
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0064 0.0099
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0032 0.008
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0205 0.0601
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0126 0.0828 0.3447
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0256 0.1063
Echinococcus multilocularis lamin dm0 0.0028 0.0115 0.0115
Treponema pallidum phosphoglycerate kinase 0.0344 0.2403 0.3744
Plasmodium vivax DNA repair protein REV1, putative 0.0029 0.0124 0.0513
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0045 0.0045
Leishmania major glucose transporter, lmgt3 0.0015 0.0025 0.0101
Onchocerca volvulus 0.0015 0.0025 0.0073
Onchocerca volvulus 0.0483 0.3409 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0616 0.2561
Loa Loa (eye worm) hypothetical protein 0.0236 0.1618 0.4138
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0061 0.0196
Brugia malayi hypothetical protein 0.0483 0.3409 0.8717
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0263 0.0671
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.012 0.0782 0.0782
Brugia malayi jmjC domain containing protein 0.006 0.0351 0.0897
Brugia malayi Phosphoglycerate kinase 0.0344 0.2403 0.6144
Schistosoma mansoni survival motor neuron protein 0.0048 0.0263 0.0262
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0344 0.2403 0.3776
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0405 0.0405
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.023 0.0956
Trypanosoma cruzi hexose transporter 0.0015 0.0025 0.0101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0299 0.1243
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0467 0.1194
Echinococcus granulosus Solute carrier family 22 5 0.1066 0.7622 0.7622
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0365 0.2554 0.7491
Giardia lamblia Phosphoglycerate kinase 0.0344 0.2403 0.3776
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0064 0.0048
Trypanosoma brucei phosphoglycerate kinase 0.0126 0.0828 0.3447
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0032 0.013
Brugia malayi DIX domain containing protein 0.0018 0.0045 0.0115
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0061 0.0178
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0007 0.0016
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0037 0.0036
Plasmodium falciparum glutathione reductase 0.0016 0.0033 0.0137
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0032 0.0032
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0432 0.1103
Schistosoma mansoni DNA polymerase IV / kappa 0.0029 0.0124 0.0123
Schistosoma mansoni inositol monophosphatase 0.0037 0.0181 0.0181
Brugia malayi RasGEF domain containing protein 0.0013 0.0008 0.0019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Onchocerca volvulus 0.0012 0.0001 0.0002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0071 0.0181
Echinococcus multilocularis dna polymerase eta 0.0144 0.0959 0.0959
Brugia malayi Doublecortin family protein 0.002 0.0062 0.0158
Schistosoma mansoni intermediate filament proteins 0.0028 0.0115 0.0115
Trypanosoma brucei phosphoglycerate kinase, putative 0.0126 0.0828 0.3447
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0467 0.1524
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0062 0.0062
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0007 0.0016
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0062 0.0257
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0061 0.0154
Loa Loa (eye worm) inositol-1 0.0037 0.0181 0.0463
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0045 0.0045
Echinococcus multilocularis leucine aminopeptidase protein 0.0108 0.0698 0.0698
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0033 0.0137
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0025 0.0101
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Leishmania major mitochondrial DNA polymerase beta 0.031 0.2154 0.8965
Treponema pallidum fructose-bisphosphate aldolase 0.0891 0.6361 1
Brugia malayi N-terminal motif family protein 0.0013 0.0008 0.0019
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0064 0.0263
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0181 0.0284
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0157 0.0652
Giardia lamblia Fructose-bisphosphate aldolase 0.0891 0.6361 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0181 0.0284
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0032 0.0032
Leishmania major DNA polymerase eta, putative 0.0144 0.0959 0.399
Plasmodium falciparum thioredoxin reductase 0.0016 0.0033 0.0137
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0405 0.0404
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0001 0.0001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0064 0.0263
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0008 0.0007
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0032 0.013
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0256 0.0256
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0616 0.1573
Brugia malayi Sugar transporter family protein 0.0015 0.0025 0.0062
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0025 0.0101
Toxoplasma gondii facilitative glucose transporter GT1 0.0015 0.0025 0.0101
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni regulator of G protein signaling 0.0018 0.0045 0.0045
Toxoplasma gondii thioredoxin reductase 0.0047 0.0256 0.1063
Schistosoma mansoni hypothetical protein 0.0174 0.1171 0.1171
Brugia malayi ImpB/MucB/SamB family protein 0.0093 0.0587 0.1499
Trypanosoma cruzi DNA polymerase eta, putative 0.008 0.0496 0.2063
Leishmania major glucose transporter, lmgt2 0.0015 0.0025 0.0101
Echinococcus granulosus solute carrier family 22 0.0015 0.0025 0.0025
Onchocerca volvulus 0.0012 0.0001 0.0002
Schistosoma mansoni sugar transporter 0.0015 0.0025 0.0024
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.012 0.0784 0.1232
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.008
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0692 0.2258
Mycobacterium ulcerans phosphoglycerate kinase 0.0344 0.2403 0.6144
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0001 0.0001
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0033 0.0084
Onchocerca volvulus 0.0018 0.0045 0.0133
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.012 0.0782 0.2
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus multilocularis solute carrier family 22 0.0015 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0124 0.0513
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0007 0.0025
Schistosoma mansoni phosphoglycerate kinase 0.0344 0.2403 0.2402
Echinococcus multilocularis phosphoglycerate kinase 1 0.0344 0.2403 0.2403
Trypanosoma brucei glucose transporter, putative 0.0015 0.0025 0.0101
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0093 0.0587 0.1499
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0205 0.0321
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0013 0.0008 0.0008
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0002 0.0004
Schistosoma mansoni dep domain containing protein 0.0018 0.0045 0.0045
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0779 0.2541
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0793 0.0793
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0366 0.0365
Schistosoma mansoni hypothetical protein 0.002 0.0062 0.0062
Trypanosoma brucei unspecified product 0.0113 0.0735 0.3058
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.1618 0.1618
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0616 0.0615
Leishmania major DNA damage repair protein, putative 0.0029 0.0124 0.0513
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0115
Trichomonas vaginalis glutaminase, putative 0.0552 0.391 0.6147
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0064 0.0162
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0616 0.0967
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0436 0.0436
Trypanosoma brucei unspecified product 0.0064 0.0378 0.1573
Echinococcus granulosus expressed protein 0.0034 0.0163 0.0163
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0025 0.0101
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0366 0.1519
Onchocerca volvulus 0.0015 0.0025 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0126 0.0828 0.3447
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0008 0.0007
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0032 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0032 0.013
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0023 0.0056
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0012 0.0012
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0012 0.0004 0.0003
Mycobacterium leprae conserved hypothetical protein 0.002 0.0061 0.0196
Schistosoma mansoni dishevelled 0.0018 0.0045 0.0045
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0405 0.1683
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0115
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus multilocularis solute carrier family 22 0.0015 0.0025 0.0025
Trypanosoma brucei glucose transporter 2A 0.0015 0.0025 0.0101
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0001 0.0001
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0181 0.0753
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0616 0.2561
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0064 0.0263
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0062 0.0257
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0001 0.0001
Schistosoma mansoni glutaminase 0.0552 0.391 0.391
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0033 0.0033
Schistosoma mansoni lamin 0.0028 0.0115 0.0115
Echinococcus granulosus lamin 0.0028 0.0115 0.0115
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0013 0.0008 0.0007
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Brugia malayi Phosphoglycerate kinase 0.0126 0.0828 0.2118
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0045 0.0045
Leishmania major DNA polymerase eta, putative 0.008 0.0496 0.2063
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0154
Brugia malayi jmjC domain containing protein 0.0016 0.0032 0.008
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0071 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Onchocerca volvulus 0.0015 0.0025 0.0073
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0284
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0793 0.0793
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0352 0.0351
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.012 0.0782 0.2
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0033 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0025 0.0025
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0467 0.1944
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0366 0.0934
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0352 0.0352
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0775 0.1981
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus granulosus phd:f box containing protein 0.0016 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0071 0.0071
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.012 0.0782 0.2
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0093 0.0587 0.0586
Plasmodium falciparum phosphoglycerate kinase 0.0344 0.2403 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0015 0.0025 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0432 0.0678
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0692 0.2258
Echinococcus multilocularis chromobox protein 1 0.0071 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0032 0.0032
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0025 0.0101
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0025 0.0038
Brugia malayi cytosol aminopeptidase 0.0022 0.0071 0.0181
Mycobacterium ulcerans hypothetical protein 0.002 0.0061 0.0154
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0352 0.0352
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0001 0.0001
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Chlamydia trachomatis phosphoglycerate kinase 0.0344 0.2403 1
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0007 0.0016
Brugia malayi jmjC domain containing protein 0.0016 0.0032 0.008
Echinococcus granulosus dna polymerase eta 0.0144 0.0959 0.0959
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0025 0.0038
Trichomonas vaginalis rotamase, putative 0.0034 0.0163 0.0255
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0096
Leishmania major trypanothione reductase 0.0047 0.0256 0.1063
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0779 0.2541
Toxoplasma gondii hypothetical protein 0.0018 0.0045 0.0186
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0157 0.0246
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0025 0.0101
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.008
Onchocerca volvulus 0.0012 0.0001 0.0002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Onchocerca volvulus 0.0048 0.0263 0.0771
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0784 0.3261
Onchocerca volvulus 0.0015 0.0025 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.0753
Entamoeba histolytica deoxycytidyl transferase, putative 0.0093 0.0587 0.0922
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0366 0.1519
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.0753
Loa Loa (eye worm) hypothetical protein 0.0076 0.0467 0.1194
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0064 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0227 0.0666
Echinococcus multilocularis solute carrier family 22 0.0015 0.0025 0.0025
Toxoplasma gondii sugar transporter ST3 0.0015 0.0025 0.0101
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0045 0.0115
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0025 0.0038
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0692 0.2258
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0692 0.2258
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0025 0.0062
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0064 0.0162
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0421 0.2957 0.7561
Mycobacterium ulcerans sugar transporter 0.0015 0.0025 0.0062
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0163 0.0416
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0616 0.0616
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0032 0.0031
Echinococcus multilocularis expressed protein 0.0034 0.0163 0.0163
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.012 0.0782 0.3255
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0351 0.0351
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0093 0.0587 0.0587
Schistosoma mansoni ap endonuclease 0.0021 0.0064 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0007 0.0025
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.012 0.0782 0.0782
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0064 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0163 0.0255
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0126 0.0828 0.3447
Mycobacterium tuberculosis Conserved hypothetical protein 0.0093 0.0587 0.1914
Echinococcus granulosus hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis ras GTP exchange factor 0.0013 0.0008 0.0008
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Trypanosoma brucei glucose transporter 1E 0.0015 0.0025 0.0101
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0435 0.3064 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0062
Leishmania major DNA polymerase kappa, putative 0.01 0.0636 0.2644
Brugia malayi Thioredoxin reductase 0.0047 0.0256 0.0653
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0033 0.0137
Echinococcus granulosus RUN 0.002 0.0062 0.0062
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0108 0.0698 0.2902
Echinococcus multilocularis leucyl aminopeptidase 0.0022 0.0071 0.0071
Brugia malayi Inositol-1 0.0037 0.0181 0.0463
Trypanosoma brucei aminopeptidase, putative 0.0022 0.0071 0.0295
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Schistosoma mansoni hypothetical protein 0.0015 0.0025 0.0024
Trypanosoma brucei chrX additional, unordered contigs 0.0029 0.0124 0.0513
Onchocerca volvulus 0.0015 0.0025 0.0073
Trypanosoma cruzi hypothetical protein 0.0013 0.0008 0.0031
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0022 0.0071 0.0181
Schistosoma mansoni glucose transporter 0.0015 0.0025 0.0024
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0126 0.0828 0.3447
Toxoplasma gondii sugar transporter ST1 0.0015 0.0025 0.0101
Loa Loa (eye worm) sugar transporter 0.0015 0.0025 0.0062
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0064 0.0099
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0975 0.4056
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.023 0.0956
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0045 0.0045
Brugia malayi glutathione reductase 0.0047 0.0256 0.0653
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0256 0.0256
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0405 0.1683
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Schistosoma mansoni leucine aminopeptidase 0.0022 0.0071 0.0071
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0022 0.0071 0.0181
Schistosoma mansoni inositol monophosphatase 0.0037 0.0181 0.0181
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0062 0.0062
Leishmania major phosphoglycerate kinase B, cytosolic 0.0344 0.2403 1
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0001 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0366 0.0365
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0321 0.0819
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0045 0.0045
Leishmania major cytochrome p450-like protein 0.0013 0.0007 0.0025
Onchocerca volvulus 0.0015 0.0025 0.0073
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0022 0.0071 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Loa Loa (eye worm) hypothetical protein 0.0365 0.2554 0.653
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0344 0.2403 1
Onchocerca volvulus 0.0015 0.0025 0.0073
Loa Loa (eye worm) hypothetical protein 0.0153 0.1023 0.2614
Plasmodium falciparum hexose transporter 0.0015 0.0025 0.0101
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0126 0.0828 0.3447
Trypanosoma brucei phosphoglycerate kinase 0.0344 0.2403 1
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0032 0.0031
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.0784 0.3261
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0405 0.1034
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0784 0.3261
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Brugia malayi jmjC domain containing protein 0.006 0.0351 0.0897
Schistosoma mansoni ap endonuclease 0.0021 0.0064 0.0063
Brugia malayi Sugar transporter family protein 0.0015 0.0025 0.0062
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0069 0.0108
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0061 0.0154
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0366 0.0366
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0157 0.0652
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0018 0.0045 0.0115
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0064 0.0099
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0366 0.1191
Mycobacterium tuberculosis Probable reductase 0.0107 0.0692 0.2258
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0018 0.0073
Toxoplasma gondii ImpB/MucB/SamB family protein 0.008 0.0496 0.2063
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0181 0.0463
Loa Loa (eye worm) hypothetical protein 0.002 0.0062 0.0158
Trypanosoma brucei polo-like protein kinase 0.0097 0.0616 0.2561
Plasmodium vivax hexose transporter 0.0015 0.0025 0.0101
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0033 0.0137
Onchocerca volvulus Sepiapterin reductase homolog 0.0012 0.0001 0.0002
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Loa Loa (eye worm) glutathione reductase 0.0047 0.0256 0.0653
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0124 0.0513
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0025 0.0101
Onchocerca volvulus 0.0012 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0033 0.0137
Onchocerca volvulus 0.0479 0.3377 0.9907
Onchocerca volvulus 0.0013 0.0008 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0001 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0366 0.0934
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0336 0.0336
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0779 0.2541
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0033 0.0052
Schistosoma mansoni loxhd1 0.002 0.0062 0.0062
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.1618 0.1618
Brugia malayi hypothetical protein 0.002 0.0062 0.0158
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0001 0.0001
Echinococcus multilocularis muscleblind protein 1 0.0153 0.1023 0.1023
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0015 0.0025 0.0073
Toxoplasma gondii sugar transporter ST2 0.0015 0.0025 0.0101
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0045 0.0045
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0108 0.0697 0.1782
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0008 0.0012
Echinococcus multilocularis Protein lozenge 0.0061 0.0354 0.0354
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0351 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0025 0.0038
Schistosoma mansoni glucose transport protein 0.0015 0.0025 0.0024
Brugia malayi hypothetical protein 0.0236 0.1618 0.4138
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0124 0.0513
Schistosoma mansoni chromobox protein 0.0071 0.0432 0.0431
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0351 0.0351
Giardia lamblia Sugar-proton symporter 0.0015 0.0025 0.0038
Echinococcus granulosus hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni rab6-interacting 0.002 0.0062 0.0062
Toxoplasma gondii leucyl aminopeptidase LAP 0.0108 0.0698 0.2902
Leishmania major glucose transporter, lmgt1 0.0015 0.0025 0.0101
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0013 0.0008 0.0008
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0108 0.0698 0.2902
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0352 0.0351
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0344 0.2403 1
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0199 0.0199
Echinococcus multilocularis RUN 0.002 0.0062 0.0062
Leishmania major phosphoglycerate kinase C, glycosomal 0.0344 0.2403 1
Leishmania major hypothetical protein, conserved 0.0016 0.0032 0.013
Plasmodium falciparum M17 leucyl aminopeptidase 0.0108 0.0698 0.2902
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Onchocerca volvulus 0.0012 0.0001 0.0002
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0062 0.0062
Echinococcus granulosus leucyl aminopeptidase 0.0022 0.0071 0.0071
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0033 0.0137
Onchocerca volvulus 0.0015 0.0025 0.0073
Toxoplasma gondii hypothetical protein 0.005 0.0277 0.1149
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0108 0.0698 0.2902
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0062 0.0158
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.002
Schistosoma mansoni rab6-interacting 0.002 0.0062 0.0062
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0163 0.0416
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0775 0.1981
Trichomonas vaginalis rotamase, putative 0.0033 0.0157 0.0246
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0891 0.6361 1
Brugia malayi hypothetical protein 0.0015 0.0025 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0022 0.0071 0.0295
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0032 0.0032
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0001 0.0002
Echinococcus granulosus bloom syndrome protein 0.0021 0.0069 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0033 0.0137
Echinococcus granulosus solute carrier family 22 0.0015 0.0025 0.0025
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0115 0.0294
Plasmodium falciparum thioredoxin reductase 0.0047 0.0256 0.1063
Onchocerca volvulus 0.0031 0.0142 0.0418
Schistosoma mansoni chromobox protein 0.0071 0.0432 0.0431
Onchocerca volvulus 0.0015 0.0025 0.0073
Onchocerca volvulus 0.0015 0.0025 0.0073
Loa Loa (eye worm) hypothetical protein 0.0028 0.0115 0.0294
Loa Loa (eye worm) hypothetical protein 0.004 0.0205 0.0523
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0616 0.0967
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0108 0.0698 0.2275
Schistosoma mansoni sugar transporter 0.0015 0.0025 0.0024
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0157 0.0652
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0352 0.1462
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0033 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0227 0.0356
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0025 0.0025
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0025 0.0038
Brugia malayi RasGEF domain containing protein 0.0013 0.0008 0.0019
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0157 0.0652
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0344 0.2403 1
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0008 0.0012
Mycobacterium ulcerans glutaminase 0.0552 0.391 1
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0025 0.0101
Schistosoma mansoni lozenge 0.0061 0.0354 0.0353
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0467 0.1524
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0062 0.0062
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0025 0.0025
Onchocerca volvulus 0.0012 0.0001 0.0002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0779 0.2541
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0033 0.0137
Plasmodium vivax JmjC domain containing protein 0.0016 0.0032 0.013
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0002 0.0004
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0025 0.0062
Mycobacterium ulcerans endonuclease IV 0.0076 0.0467 0.1194
Mycobacterium ulcerans DNA polymerase IV 0.012 0.0784 0.2004

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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