Detailed information for compound 831599

Basic information

Technical information
  • TDR Targets ID: 831599
  • Name: N-(3,4-dimethylphenyl)-3-methyl-2-[(3-methyl- 2-oxo-1,3-benzoxazol-6-yl)sulfonylamino]butan amide
  • MW: 431.505 | Formula: C21H25N3O5S
  • H donors: 2 H acceptors: 4 LogP: 3.28 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C(C(=O)Nc1ccc(c(c1)C)C)NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C)C
  • InChi: 1S/C21H25N3O5S/c1-12(2)19(20(25)22-15-7-6-13(3)14(4)10-15)23-30(27,28)16-8-9-17-18(11-16)29-21(26)24(17)5/h6-12,19,23H,1-5H3,(H,22,25)
  • InChiKey: KQPUVYWJJYMJRX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3,4-dimethylphenyl)-2-[(2-keto-3-methyl-1,3-benzoxazol-6-yl)sulfonylamino]-3-methyl-butyramide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.1363 0.3669 1
Onchocerca volvulus 0.0096 0.0222 0.2663
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0256 0.4061
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0035 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0204 0.0517 0.265
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0049 0.0048
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0127 0.0126
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.0521 0.2068
Leishmania major protein kinase, putative 0.0016 0.0005 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Toxoplasma gondii ABC1 family protein 0.0038 0.0066 0.0664
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0041 0.0145
Trypanosoma cruzi polo-like protein kinase, putative 0.0191 0.0481 0.1397
Entamoeba histolytica casein kinase, putative 0.0136 0.0333 0.168
Trypanosoma brucei protein kinase, putative 0.0051 0.01 0.0939
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0085 0.0193 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0481 0.1687
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.0014 0.0533
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0086 0.0196 0.0196
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0066 0.1042
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.0203 0.0203
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0133 0.0324 0.1285
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.022 0.0771
Entamoeba histolytica hypothetical protein 0.0085 0.0193 0.0944
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0018 0.0164
Brugia malayi RNA binding protein 0.0058 0.0118 0.0616
Mycobacterium leprae conserved hypothetical protein 0.0085 0.0193 0.7519
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Echinococcus granulosus importin subunit beta 1 0.0029 0.0041 0.004
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0204 0.0517 0.1501
Leishmania major importin beta-1 subunit, putative 0.0024 0.0026 0.0068
Schistosoma mansoni kinase 0.0098 0.0229 0.0803
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0066 0.1042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.0049
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.01 0.027
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.032 0.0832 0.0831
Onchocerca volvulus 0.0038 0.0066 0.0789
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.014 0.0342 0.0341
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0019 0.0014 0.0144
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0014 0.0068
Onchocerca volvulus 0.01 0.0234 0.2807
Schistosoma mansoni serine/threonine protein kinase 0.032 0.0832 0.292
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0014 0.0046
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0032 0.0049 0.0048
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0164 0.0408 0.1431
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4916
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0164 0.0408 0.0407
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0408 0.111
Schistosoma mansoni hypothetical protein 0.0051 0.0101 0.0352
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0223 0.11
Trypanosoma brucei polo-like protein kinase 0.0191 0.0481 0.454
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0085 0.0193 0.4719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0264 0.0679 0.3503
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0616 0.3174
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.02 0.0505 0.1467
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0717 0.1912 1
Brugia malayi Death domain containing protein 0.0014 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0042 0.0145
Leishmania major phosphatidylinositol kinase, putative 0.0085 0.0193 0.0523
Schistosoma mansoni voltage-gated cation channel 0.0032 0.0049 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.01 0.0454
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0344 0.0897 0.8471
Toxoplasma gondii hypothetical protein 0.0053 0.0107 0.107
Echinococcus granulosus voltage dependent calcium channel 0.0032 0.0049 0.0048
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0085 0.0193 0.0944
Entamoeba histolytica hypothetical protein 0.0596 0.1584 0.8271
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0035 0.0111
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0085 0.0193 0.1006
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0164 0.0408 0.0407
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0014 0.0052
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0127 0.0367
Onchocerca volvulus 0.0085 0.0193 0.2311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0219 0.0557 0.2859
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0717 0.1912 0.5561
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0191 0.0481 0.1309
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0061 0.0572
Loa Loa (eye worm) calcium channel 0.0032 0.0049 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0344 0.0897 0.4653
Schistosoma mansoni ran 0.0021 0.002 0.0068
Echinococcus multilocularis 0.0085 0.0193 0.0192
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0066 0.0066
Entamoeba histolytica serine/threonine protein kinase, putative 0.0191 0.0481 0.2461
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0014 0.0052
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0532 0.1409 0.735
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0041 0.0414
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0061 0.0611
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.01 0.2215
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.0049
Onchocerca volvulus Serine\/threonine kinase homolog 0.0191 0.0481 0.5778
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0066 0.0277
Loa Loa (eye worm) phosphatidylinositol 3 0.0085 0.0193 0.0763
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4916
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0256 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0394 0.1033 0.3628
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.002 0.0198
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0191
Echinococcus multilocularis expressed conserved protein 0.0081 0.0183 0.0182
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0256 0.0898
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.0145
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0052
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0014 0.0533
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0032 0.0049 0.0048
Echinococcus multilocularis tumor protein p63 0.0336 0.0877 0.0876
Loa Loa (eye worm) cytochrome P450 0.0014 0.0001 0.0001
Echinococcus granulosus intermediate filament protein 0.0027 0.0034 0.0034
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus granulosus lamin dm0 0.0027 0.0034 0.0034
Brugia malayi Csnk2b protein 0.0036 0.0061 0.0316
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0018 0.0022
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0164 0.0408 0.1618
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0023 0.0078
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0261
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0041 0.0382
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0085 0.0193 0.0559
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0066 0.1042
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0026 0.0073
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0014 0.0068
Brugia malayi Casein kinase II, alpha chain 0.0136 0.0333 0.1737
Brugia malayi Serotonin receptor 0.0467 0.1232 0.6439
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0014 0.0013
Leishmania major DNA polymerase kappa, putative 0.0021 0.0018 0.0046
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0403 0.1059 0.1058
Echinococcus granulosus snurportin 1 0.031 0.0806 0.0806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0616 0.3174
Leishmania major phosphatidylinositol 3-kinase, putative 0.0164 0.0408 0.111
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Echinococcus granulosus protein kinase shaggy 0.0051 0.01 0.0099
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0256 0.2416
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0023 0.0022
Mycobacterium tuberculosis Conserved protein 0.0038 0.0066 0.1042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.022 0.0219
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0024 0.0069
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0014 0.0046
Schistosoma mansoni hypothetical protein 0.031 0.0806 0.2831
Brugia malayi SH2 domain containing protein 0.0338 0.0883 0.4614
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Schistosoma mansoni DNA polymerase eta 0.0021 0.0018 0.006
Entamoeba histolytica protein kinase rad3, putative 0.0204 0.0517 0.265
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.014 0.0342 0.0341
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0403 0.1059 1
Brugia malayi Serine/threonine-protein kinase Pim-3 0.032 0.0832 0.4348
Entamoeba histolytica hypothetical protein 0.0036 0.0059 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0014 0.0057
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0108 0.0426
Entamoeba histolytica hypothetical protein 0.0036 0.0059 0.024
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0118 0.0413
Echinococcus granulosus lamin 0.0027 0.0034 0.0034
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0034 0.0134
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0204 0.0517 0.0516
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0018 0.0666
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0164 0.0408 0.0407
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0024 0.0069
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.106 0.2847 0.2847
Entamoeba histolytica hypothetical protein 0.0219 0.0557 0.2859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.1009 0.5243
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0085 0.0193 0.1006
Leishmania major phosphatidylinositol 3-kinase, putative 0.0344 0.0897 0.2443
Entamoeba histolytica hypothetical protein 0.0024 0.0026 0.0064
Leishmania major GTP-binding protein, putative 0.0021 0.002 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0193 0.4719
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0023 0.0116
Giardia lamblia Kinase, CMGC GSK 0.0051 0.01 0.0772
Schistosoma mansoni importin beta-1 0.0029 0.0041 0.0141
Brugia malayi PXA domain containing protein 0.002 0.0017 0.0089
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0042 0.0145
Loa Loa (eye worm) RNA binding protein 0.0058 0.0118 0.0468
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.000000010102
Leishmania major hypothetical protein, unknown function 0.0085 0.0193 0.0523
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.022 0.0771
Loa Loa (eye worm) hypothetical protein 0.014 0.0342 0.1356
Schistosoma mansoni lamin 0.0027 0.0034 0.0118
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0332 0.0865 0.3038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0043
Leishmania major phosphatidylinositol 4-kinase, putative 0.0085 0.0193 0.0523
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.022 0.0219
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0118 0.0413
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.002 0.0056
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0041 0.004
Giardia lamblia GTOR 0.0403 0.1059 0.9794
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Brugia malayi Protein kinase domain containing protein 0.0018 0.001 0.0048
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0085 0.0193 0.1934
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0017 0.0067
Loa Loa (eye worm) hypothetical protein 0.0225 0.0573 0.2273
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0034 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0107 0.049
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0096 0.0334
Trichomonas vaginalis esterase, putative 0.0038 0.0066 0.0277
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0026 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0107 0.049
Echinococcus multilocularis musashi 0.0027 0.0034 0.0034
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0256 0.0256
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0032 0.0049 0.0168
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0086 0.0197 0.0689
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0061 0.0164
Schistosoma mansoni intermediate filament proteins 0.0027 0.0034 0.0118
Loa Loa (eye worm) hypothetical protein 0.0338 0.0883 0.3503
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0127 0.0597
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.0145
Brugia malayi Importin beta-1 subunit 0.0029 0.0041 0.0211
Giardia lamblia Hypothetical protein 0.0085 0.0193 0.1646
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0127 0.0597
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0285 0.0736 0.2139
Onchocerca volvulus 0.0051 0.01 0.1193
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0018 0.0022
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.01 0.0288
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0059 0.229
Mycobacterium ulcerans hypothetical protein 0.0038 0.0066 0.2565
Brugia malayi Cytochrome P450 family protein 0.0023 0.0024 0.0125
Schistosoma mansoni ran 0.0021 0.002 0.0068
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0191 0.0481 0.048
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0018 0.0164
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0059 0.0059
Loa Loa (eye worm) phosphatidylinositol 3 0.0085 0.0193 0.0763
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0085 0.0193 0.1818
Onchocerca volvulus 0.0027 0.0034 0.0404
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.002 0.02
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0219 0.0557 0.1617
Trichomonas vaginalis PIKK family atypical protein kinase 0.0344 0.0897 0.4653
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0333 0.168
Loa Loa (eye worm) hypothetical protein 0.0247 0.0635 0.2518
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.016
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0121 0.0292 0.2757
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0245 0.063 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4914
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0164 0.0408 0.2077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.0049
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0041 0.0145
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0515 0.1362 0.1362
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0027
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.01 0.2437
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0178 0.0446 0.1768
Entamoeba histolytica hypothetical protein 0.0085 0.0193 0.0944
Echinococcus granulosus dna polymerase eta 0.0021 0.0018 0.0017
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0066 0.2565
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0085 0.0193 0.4564
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0014 0.0013
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0018 0.006
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0717 0.1912 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0378
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0164
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0035 0.0179
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0164 0.0408 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Trichomonas vaginalis ran, putative 0.0021 0.002 0.0033
Echinococcus multilocularis snurportin 1 0.031 0.0806 0.0806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0367 0.096 0.4982
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0014 0.0013
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0014 0.0068
Entamoeba histolytica hypothetical protein 0.0036 0.0059 0.024
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0085 0.0193 0.0944
Loa Loa (eye worm) hypothetical protein 0.01 0.0234 0.0928
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0344 0.0896 0.4686
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0403 0.1059 0.1058
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0403 0.1059 0.5505
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0164 0.0408 0.2077
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0001 0.0007
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.01 0.0394
Onchocerca volvulus 0.0038 0.0066 0.0789
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0041 0.0414
Brugia malayi hypothetical protein 0.0469 0.1238 0.6473
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Onchocerca volvulus 0.0038 0.0066 0.0789
Schistosoma mansoni fkbp-rapamycin associated protein 0.0204 0.0517 0.1814
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0066 0.1614
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0215 0.0546 0.2803
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0127 0.0367
Schistosoma mansoni hypothetical protein 0.0167 0.0417 0.1464
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0403 0.1059 0.5505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0052
Echinococcus granulosus dna polymerase kappa 0.0021 0.0018 0.0017
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0164 0.0408 0.2077
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0256 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0041 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0014 0.0013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0066 0.023
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0018 0.0017
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0018 0.027
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.0014 0.0217
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0019 0.0029
Echinococcus granulosus casein kinase ii subunit alpha 0.0136 0.0333 0.0332
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0001 0.0000090462
Brugia malayi hypoxia-induced factor 1 0.015 0.037 0.193
Echinococcus multilocularis Zinc finger, PHD finger 0.0164 0.0408 0.0407
Brugia malayi 6-phosphofructokinase 0.0108 0.0256 0.1337
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0066 0.0277
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0085 0.0193 0.0192
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0256 0.1015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0238 0.0608 0.2414
Trichomonas vaginalis set domain proteins, putative 0.0234 0.0598 0.308
Schistosoma mansoni single-minded 0.0048 0.0093 0.0326
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0136
Brugia malayi FAT domain containing protein 0.014 0.0342 0.1786
Plasmodium vivax SET domain protein, putative 0.0029 0.0042 0.1018
Schistosoma mansoni hypothetical protein 0.0085 0.0193 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.1009 0.5243
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0061 0.0175
Brugia malayi Cytochrome P450 family protein 0.0054 0.0108 0.0561
Brugia malayi 6-phosphofructokinase 0.0108 0.0256 0.1337
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0018 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0394 0.1033 0.3004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0042 0.0145
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0059 0.0307
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0394 0.1033 0.1033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0245 0.0629 0.324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0215 0.0546 0.2803
Brugia malayi beta-lactamase family protein 0.0038 0.0066 0.0344
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.002 0.0077
Echinococcus multilocularis survival motor neuron protein 1 0.0469 0.1238 0.1237
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0032 0.0049 0.0251
Brugia malayi intermediate filament protein 0.0027 0.0034 0.0176
Brugia malayi beta-lactamase 0.0038 0.0066 0.0344
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0049 0.0048
Toxoplasma gondii FATC domain-containing protein 0.0219 0.0557 0.5584
Trypanosoma brucei unspecified product 0.0021 0.0018 0.0164
Echinococcus multilocularis casein kinase ii subunit alpha 0.0136 0.0333 0.0332
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0256 0.1277
Echinococcus granulosus bloom syndrome protein 0.0021 0.0019 0.0018
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0164 0.0408 1
Toxoplasma gondii ck2 beta subunit 0.0036 0.0061 0.0611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0344 0.0897 0.4653
Loa Loa (eye worm) phosphatidylinositol 3 0.0354 0.0926 0.3676
Loa Loa (eye worm) phosphatidylinositol 3 0.0085 0.0193 0.0763
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0532 0.1409 0.735
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0061 0.0249
Loa Loa (eye worm) hypothetical protein 0.0026 0.0033 0.0128
Brugia malayi Pre-SET motif family protein 0.0206 0.0521 0.2723
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0049 0.0048
Onchocerca volvulus 0.01 0.0234 0.2807
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0408 0.4093
Trichomonas vaginalis conserved hypothetical protein 0.0119 0.0286 0.1433
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0023 0.0088
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0394 0.1033 0.1033
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0005 0.0013
Brugia malayi Pre-SET motif family protein 0.0029 0.0042 0.0217
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.01 0.0454
Loa Loa (eye worm) hypothetical protein 0.01 0.0234 0.0927
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0403 0.1059 0.5536
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0256 0.0898
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0164 0.0408 0.1431
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.0014 0.0217
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0354 0.0926 0.2523
Plasmodium vivax hypothetical protein 0.0085 0.0193 0.4719
Brugia malayi follicle stimulating hormone receptor 0.0238 0.0608 0.318
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0191 0.0481 0.048
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0219 0.0557 0.1953
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0014 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4916
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.1009 0.5243
Leishmania major phosphatidylinositol kinase related protein, putative 0.01 0.0232 0.0632
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0261
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0403 0.1059 0.3078
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0059 0.0206
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0014 0.0013
Brugia malayi beta-lactamase family protein 0.0038 0.0066 0.0344
Brugia malayi Cytochrome P450 family protein 0.0014 0.0001 0.0001
Brugia malayi RNA recognition motif domain containing protein 0.0058 0.0118 0.0616
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0005 0.0013
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Loa Loa (eye worm) phosphatidylinositol kinase 0.0085 0.0193 0.0763
Brugia malayi PXA domain containing protein 0.002 0.0017 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.1278 0.3438 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0001 0.0004
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0014 0.0013
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0041 0.1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.0242 0.1205
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.0001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0041 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.1009 0.5243
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0024 0.0228
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0066 0.0261
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0014 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.0286 0.1433
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0066 0.0277
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.002 0.0056
Brugia malayi hypothetical protein 0.0019 0.0014 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0225 0.0573 0.2946
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.01 0.0348
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0052
Brugia malayi phosphofructokinase 0.0108 0.0256 0.1337
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0394 0.1033 0.5402
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0041 0.0736
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0018 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0118 0.0413
Mycobacterium tuberculosis Conserved protein 0.0038 0.0066 0.1042
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0085 0.0193 0.1934
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0717 0.1912 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0041 0.1
Toxoplasma gondii target of rapamycin (TOR), putative 0.038 0.0997 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0219 0.0557 0.2908
Loa Loa (eye worm) CAMK/PIM protein kinase 0.032 0.0832 0.3301
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0068
Toxoplasma gondii hypothetical protein 0.0019 0.0014 0.0144
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0061 0.0249
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.01 0.0099
Toxoplasma gondii CMGC kinase, CK2 family 0.0136 0.0333 0.3338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0085 0.0193 0.0944
Loa Loa (eye worm) beta-lactamase 0.0038 0.0066 0.0261
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0035 0.0034
Giardia lamblia Kinase, CMGC CK2 0.0136 0.0333 0.2962
Schistosoma mansoni lamin 0.0027 0.0034 0.0118
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0014 0.0013
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0035 0.0111
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0085 0.0193 0.4719
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0408 0.4093
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.022 0.0872
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0127 0.0597
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0061 0.0212
Schistosoma mansoni hypothetical protein 0.0081 0.0183 0.0639
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0085 0.0193 0.0559
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0014 0.0144
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0807 0.2158 0.2158
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0073 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Schistosoma mansoni survival motor neuron protein 0.0096 0.0222 0.0778
Brugia malayi Cytochrome P450 family protein 0.0023 0.0024 0.0125
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0261
Loa Loa (eye worm) RecQ helicase 0.0021 0.0019 0.0074
Loa Loa (eye worm) hypothetical protein 0.0085 0.0193 0.0763
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0014 0.0046
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0066 0.2565
Brugia malayi hypothetical protein 0.0019 0.0014 0.0068
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0261
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0717 0.1912 1
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0256 0.1277
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0074 0.032
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0093 0.0326
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0085 0.0193 0.4564
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Brugia malayi PAS domain containing protein 0.0048 0.0093 0.0486
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0061 0.006
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0161 0.0161
Leishmania major casein kinase II, putative 0.0136 0.0333 0.0905
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0085 0.0193 0.0192
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0014 0.0046
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0019 0.0029
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0049 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0256 0.1277
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0256 0.1277
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0164 0.0408 0.2077
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0018 0.009
Echinococcus multilocularis lamin 0.0027 0.0034 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0024 0.0095
Loa Loa (eye worm) hypothetical protein 0.0469 0.1238 0.4914
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0107 0.049
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0066 0.1042
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0014 0.0533
Echinococcus granulosus serine protein kinase ATM 0.0219 0.0557 0.0556
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0394 0.1033 0.3004
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0018 0.009
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.002 0.0185
Leishmania major protein kinase, putative 0.0016 0.0005 0.0012
Entamoeba histolytica hypothetical protein 0.0085 0.0193 0.0944
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0032 0.0049 0.0168
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0061 0.0725
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0403 0.1059 0.3078
Entamoeba histolytica Ran family GTPase 0.0021 0.002 0.0033
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0403 0.1059 0.3718
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Leishmania major hypothetical protein, conserved 0.0038 0.0066 0.0179
Loa Loa (eye worm) gastrulation defective protein 1 0.013 0.0315 0.1249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0085 0.0193 0.0944
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0014 0.0013
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0014 0.0013
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0035 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4914
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0059 0.0059
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.033 0.0859 0.4453
Loa Loa (eye worm) phosphatidylinositol 3 0.0085 0.0193 0.0763
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0066 0.0277
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0136 0.0333 0.1319
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0058 0.0118 0.0468
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0059 0.0059
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0014 0.0046
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0385 0.1009 0.9531
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0085 0.0193 0.0192
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0061 0.1234
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.038 0.0997 0.5177
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0024 0.0095
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0256 0.0696
Mycobacterium tuberculosis Conserved protein 0.0038 0.0066 0.1042
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0018 0.027
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0256 0.1277
Brugia malayi Protein kinase domain containing protein 0.0133 0.0324 0.1692
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.002 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0342 0.1729
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0243 0.0623 0.5881
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0014 0.0068
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.0203 0.0203
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0178 0.0446 0.2329
Schistosoma mansoni hypothetical protein 0.0096 0.0222 0.0778
Trypanosoma cruzi target of rapamycin kinase 3 0.0385 0.1009 0.2934
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0354 0.0926 0.8746
Brugia malayi cytochrome P450 0.0014 0.0001 0.0001
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.000000010102
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.106 0.2847 0.2847
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0042 0.0041
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0005 0.0013
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0127 0.0126
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0042 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4916
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0085 0.0193 0.0192
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0717 0.1912 0.5561
Onchocerca volvulus 0.0085 0.0193 0.2311
Echinococcus multilocularis cyclin dependent kinase 19 0.0133 0.0324 0.0323
Brugia malayi hypothetical protein 0.0162 0.0404 0.2109
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0349 0.0911 0.4727
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0018 0.0017
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.032 0.0832 0.0831
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0256 0.1277
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0018 0.0164
Giardia lamblia Kinase, CMGC GSK 0.0051 0.01 0.0772
Schistosoma mansoni hypothetical protein 0.0167 0.0417 0.1464
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0074 0.032
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0085 0.0193 0.0675
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0127 0.0367
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0052
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0403 0.1059 0.2884
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0014 0.0013
Echinococcus granulosus tumor protein p63 0.0336 0.0877 0.0876
Trypanosoma brucei Casein kinase II 0.0136 0.0333 0.3139
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0285 0.0736 0.3805
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0061 0.1234
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0052
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0225 0.0573 0.575
Schistosoma mansoni protein kinase 0.0136 0.0333 0.1166
Trypanosoma cruzi polo-like protein kinase, putative 0.0191 0.0481 0.1397
Loa Loa (eye worm) phosphatidylinositol 3 0.0403 0.1059 0.4203
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0061 0.0249
Onchocerca volvulus 0.0036 0.0059 0.0705
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0285 0.0736 0.6951
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0085 0.0193 0.1818
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0023 0.0078
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0061 0.0725
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0014 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.02 0.0505 0.2003
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0596 0.1584 0.8271
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0066 0.0191
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0034 0.0176
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0206 0.0521 0.4733
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0085 0.0193 0.1006
Plasmodium falciparum casein kinase 2, alpha subunit 0.0136 0.0333 0.8098
Leishmania major DNA polymerase eta, putative 0.0021 0.0018 0.0046
Echinococcus granulosus tar DNA binding protein 0.0058 0.0118 0.0118
Echinococcus multilocularis serine protein kinase ATM 0.0219 0.0557 0.0556
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0066 0.1042
Schistosoma mansoni hypothetical protein 0.0036 0.0059 0.0206
Loa Loa (eye worm) hypothetical protein 0.0162 0.0404 0.1601
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0517 0.1369 0.7156
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0127 0.1196
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0204 0.0517 0.2701
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0014 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0403 0.1059 0.5505
Loa Loa (eye worm) CAMK/PIM protein kinase 0.032 0.0832 0.3301
Echinococcus granulosus survival motor neuron protein 1 0.0469 0.1238 0.1237
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0018 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0367 0.096 0.4982
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0018 0.0049
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0285 0.0736 0.3848
Brugia malayi Protein kinase domain containing protein 0.032 0.0832 0.4348
Echinococcus granulosus expressed protein 0.0372 0.0973 0.0972
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0256 0.1015
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0066 0.0066
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0041 0.0409
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0066 0.0623
Brugia malayi hypothetical protein 0.01 0.0234 0.1223
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0014 0.0013
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0127 0.1196
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.022 0.0219
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0018 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0947 0.4914
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0222 0.1159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.022 0.0771
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.0049
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0085 0.0193 0.0559
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0032 0.0049 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0014 0.0533
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0191 0.0481 0.1908
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0018 0.0666
Mycobacterium ulcerans lipase LipD 0.0038 0.0066 0.2565
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0014 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.0145
Loa Loa (eye worm) TAR-binding protein 0.0058 0.0118 0.0468
Echinococcus multilocularis expressed protein 0.0372 0.0973 0.0972
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0035 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0035 0.0179
Plasmodium vivax unspecified product 0.0136 0.0333 0.8153
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0085 0.0193 0.0944
Onchocerca volvulus 0.0041 0.0073 0.0866
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0039 0.0038
Brugia malayi M-phase phosphoprotein, mpp8 0.01 0.0234 0.1221
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0066 0.0277
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.022 0.1148
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0041 0.0414
Trypanosoma cruzi casein kinase II, putative 0.0136 0.0333 0.0966
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0256 0.1015
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0042 0.0421
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.032 0.0832 1
Plasmodium falciparum importin beta, putative 0.0029 0.0041 0.0726
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0014 0.0046
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0411 0.1081 1
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0014 0.034
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Entamoeba histolytica protein kinase, putative 0.0051 0.01 0.0454
Echinococcus multilocularis protein kinase shaggy 0.0051 0.01 0.0099
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0403 0.1059 1
Echinococcus multilocularis high voltage activated calcium channel beta 0.0086 0.0197 0.0196
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0408 0.1185
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0136 0.0333 0.8153
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0403 0.1059 0.5505
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0014 0.0013
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0385 0.1009 0.2749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0354 0.0926 0.4806
Mycobacterium tuberculosis Conserved hypothetical protein 0.0085 0.0193 0.3054
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0049 0.0048
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0161 0.0161
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0061 0.1483
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0085 0.0193 0.1934
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0085 0.0193 0.0675
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.002 0.0477
Echinococcus multilocularis dna polymerase eta 0.0021 0.0018 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0481 0.2461
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0052
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0024 0.0929
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0408 0.1185
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0074 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0023 0.0078
Echinococcus multilocularis 0.0014 0.0001 0.0000090462
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0085 0.0193 0.0675
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0344 0.0897 0.4653
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0048 0.0091 0.0359
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0164 0.0408 0.2077
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0066 0.0191
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0066 0.1042
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Brugia malayi hypothetical protein 0.0036 0.0059 0.0307
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.022 0.0219
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0408 0.385
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0061 0.0175
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0085 0.0193 0.4719
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0066 0.0344
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0403 0.1059 0.5505
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0014 0.0013
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0061 0.0127 0.0444
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0717 0.1912 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.002 0.0019
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0018 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0064
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0285 0.0736 0.3805
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0007 0.0022
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0134 0.0325 0.0945
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.0806 0.32
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.01 0.0454
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0066 0.023
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0042 0.0041
Giardia lamblia Casein kinase II beta chain 0.0036 0.0061 0.0406
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0632 0.1681 0.8783
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.01 0.0454
Brugia malayi RNA, U transporter 1 0.0083 0.0187 0.0974
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0024 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0164
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0403 0.1059 0.2884
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.01 0.0099
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.037 0.1465
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0086 0.0196 0.0196
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.3689 1 1
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0061 0.024
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0019 0.0097
Echinococcus granulosus cyclin dependent kinase 19 0.0133 0.0324 0.0323
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0285 0.0736 0.3805
Onchocerca volvulus 0.0027 0.0034 0.0404
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0127 0.0597
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0203 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0014 0.0004
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0023 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0118 0.0413
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.01 0.0232 0.0674
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Plasmodium vivax importin-beta 2, putative 0.0029 0.0041 0.099
Loa Loa (eye worm) hypothetical protein 0.0134 0.0325 0.129
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0256 0.0743
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0014 0.0046
Leishmania major cytochrome p450-like protein 0.0023 0.0024 0.0065
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0014 0.0013
Giardia lamblia Kinase, PLK 0.0191 0.0481 0.4357
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0285 0.0736 0.3805
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0041 0.5
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0049 0.0048
Echinococcus granulosus geminin 0.0167 0.0417 0.0417
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0515 0.1362 0.1362
Echinococcus multilocularis geminin 0.0167 0.0417 0.0417
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0085 0.0193 0.0559
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0256 1
Echinococcus granulosus single minded 2 0.0036 0.0059 0.0059
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.01 0.1001
Echinococcus granulosus high voltage activated calcium channel beta 0.0086 0.0197 0.0196
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0333 0.168
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0005 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0266 0.0685 0.3536
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0256 0.1277
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0219 0.0557 0.5254
Brugia malayi TAR-binding protein 0.0058 0.0118 0.0616
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0515 0.1362 0.5408
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0023 0.0022
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0041 0.0736
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0066 0.2565
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0064
Echinococcus granulosus expressed conserved protein 0.0081 0.0183 0.0182
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0014 0.0046
Mycobacterium ulcerans beta-lactamase 0.0038 0.0066 0.2565
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0001 0.000000035489
Onchocerca volvulus 0.0234 0.0599 0.7197
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0061 0.1483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.1009 0.5243
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0223 0.11
Brugia malayi intracellular kinase 0.0051 0.01 0.0519
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.106 0.2847 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0191 0.0481 0.2513
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0061 0.0249
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0066 0.1042
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0014 0.0013
Giardia lamblia Phosphatidylinositol 4-kinase 0.0085 0.0193 0.1646
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.0145
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0203 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0324 0.1136
Schistosoma mansoni hypothetical protein 0.014 0.0342 0.1199
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0204 0.0517 0.0516
Entamoeba histolytica hypothetical protein 0.0036 0.0059 0.024
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0041 0.0382
Onchocerca volvulus 0.0049 0.0096 0.1143
Loa Loa (eye worm) hypothetical protein 0.0204 0.0517 0.205
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0127 0.0597
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0164 0.0408 0.2131
Echinococcus multilocularis lamin dm0 0.0027 0.0034 0.0034
Mycobacterium leprae Probable lipase LipE 0.0038 0.0066 0.2565
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.0145
Echinococcus multilocularis tar DNA binding protein 0.0058 0.0118 0.0118
Schistosoma mansoni tar DNA-binding protein 0.0058 0.0118 0.0413
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0256 0.0256
Loa Loa (eye worm) phosphatidylinositol 3 0.094 0.2519 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.002 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0616 0.3174
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.01 0.0394

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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