Detailed information for compound 843145

Basic information

Technical information
  • TDR Targets ID: 843145
  • Name: N-butyl-N-(furan-2-ylmethyl)-2-(8-methyl-4H-c hromeno[3,4-d]pyrazol-1-yl)acetamide
  • MW: 379.452 | Formula: C22H25N3O3
  • H donors: 0 H acceptors: 2 LogP: 3.28 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN(C(=O)Cn1ncc2c1c1cc(C)ccc1OC2)Cc1ccco1
  • InChi: 1S/C22H25N3O3/c1-3-4-9-24(13-18-6-5-10-27-18)21(26)14-25-22-17(12-23-25)15-28-20-8-7-16(2)11-19(20)22/h5-8,10-12H,3-4,9,13-15H2,1-2H3
  • InChiKey: RZWJWHXKHHGOMM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-butyl-N-(2-furylmethyl)-2-(8-methyl-4H-chromeno[3,4-d]pyrazol-1-yl)acetamide
  • N-butyl-N-(furan-2-ylmethyl)-2-(8-methyl-4H-chromeno[3,4-d]pyrazol-1-yl)ethanamide
  • IDI1_028382
  • ChemDiv3_010824

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0013 0.0041
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0013 0.0041
Trypanosoma brucei glucosidase, putative 0.0035 0.0067 0.091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.0109
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0479 0.1683
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0174 0.1792
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0013 0.0041
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0053 0.6046
Brugia malayi ecdysteroid receptor 0.0038 0.0076 0.0263
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0013 0.0012
Onchocerca volvulus 0.0086 0.0239 0.0732
Loa Loa (eye worm) hypothetical protein 0.0114 0.033 0.1159
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0086 0.0239 0.0837
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0053
Loa Loa (eye worm) PAN domain-containing protein 0.0016 0.0003 0.0006
Echinococcus granulosus expressed protein 0.0035 0.0066 0.0064
Onchocerca volvulus 0.0016 0.0003 0.0003
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0083 0.0189
Plasmodium vivax hypothetical protein, conserved 0.0056 0.0136 0.3689
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0013 0.0041
Schistosoma mansoni hypothetical protein 0.0175 0.0537 0.1236
Echinococcus multilocularis geminin 0.0175 0.0537 0.0536
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0079 0.1573
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0009 0.0028
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0018 0.0017
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0104 0.0297 0.104
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0018 0.0017
Brugia malayi hypothetical protein 0.002 0.0017 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0083 0.0229
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0056 0.0136 0.3689
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0053 0.0134
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0009 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.0076 0.0228
Brugia malayi CXXC zinc finger family protein 0.003 0.0049 0.0168
Toxoplasma gondii PAN domain-containing protein 0.0016 0.0003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0048 0.0165
Entamoeba histolytica hypothetical protein, conserved 0.0056 0.0136 0.4124
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0331 0.3961
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0083 0.0288
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0048 0.222
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0083 0.0082
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0013 0.0041
Onchocerca volvulus 0.0982 0.3237 1
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0013 0.0012
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0013 0.0041
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0018 0.0105
Plasmodium falciparum thrombospondin-related anonymous protein 0.0056 0.0136 0.6465
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Plasmodium vivax SET domain protein, putative 0.0124 0.0366 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0083 0.0189
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0067 0.1164
Loa Loa (eye worm) solute carrier family 6 member 4 0.0016 0.0002 0.0003
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.0076 0.0172
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.0076 0.0172
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0009 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.0076 0.0263
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0013 0.0012
Onchocerca volvulus 0.0056 0.0136 0.0415
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0331 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0081 0.0879
Toxoplasma gondii hypothetical protein 0.0016 0.0002 0.0028
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.0076 0.0172
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0083 0.0082
Brugia malayi nuclear hormone receptor 0.0038 0.0076 0.0263
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0003
Echinococcus multilocularis expressed protein 0.0777 0.2552 0.2551
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0141 0.0423 0.1488
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0009 0.0028
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0063 0.1018
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0053
Brugia malayi hypothetical protein 0.0018 0.001 0.0028
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.021 0.0734
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0067 0.0819
Loa Loa (eye worm) PAN domain-containing protein 0.0016 0.0003 0.0006
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0479 0.0477
Mycobacterium ulcerans aldehyde dehydrogenase 0.026 0.082 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Echinococcus granulosus voltage dependent calcium channel subunit 0.1365 0.4521 0.452
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0009 0.0028
Loa Loa (eye worm) RecQ helicase 0.0042 0.0091 0.0315
Brugia malayi hypothetical protein 0.002 0.0017 0.0053
Echinococcus granulosus axis inhibition protein axin 0.004 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Echinococcus multilocularis leukotriene A 4 hydrolase 0.024 0.0755 0.0753
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.026 0.082 1
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0091 0.0252
Brugia malayi metabotropic glutamate receptor type 2 0.0045 0.01 0.0348
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0331 1
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0288
Schistosoma mansoni regulator of G protein signaling 0.004 0.0083 0.0189
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.0138
Schistosoma mansoni DNA helicase recq5 0.0029 0.0048 0.0108
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0067 0.0066
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.0076 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0173
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0053 0.243
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0331 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.0076 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0083 0.0229
Onchocerca volvulus 0.0086 0.0239 0.0732
Echinococcus multilocularis expressed protein 0.0035 0.0066 0.0064
Brugia malayi hypothetical protein 0.004 0.0083 0.0288
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0049 0.0168
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0013 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0331 0.0995
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0016 0.0002 0.0003
Brugia malayi hypothetical protein 0.0247 0.0779 0.2739
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0013 0.0041
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0013 0.0012
Loa Loa (eye worm) norepinephrine transporter 0.0016 0.0002 0.0003
Echinococcus granulosus GPCR family 2 0.0045 0.01 0.0098
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0056 0.0136 0.0135
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0013 0.0012
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0083 0.0082
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0013 0.0012
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0091 0.0089
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0331 0.0578
Toxoplasma gondii PAN/Apple domain-containing protein 0.0016 0.0003 0.0039
Toxoplasma gondii PAN domain-containing protein 0.0016 0.0003 0.0039
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0002 0.0001
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0009 0.0008
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0057 0.0564
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0018 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0067 0.0178
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0083 0.0288
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0067 0.0178
Echinococcus multilocularis nAChR subunit 0.0019 0.0013 0.0012
Echinococcus multilocularis musashi 0.0086 0.0239 0.0237
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0119 0.0413
Brugia malayi laminin alpha chain 0.0052 0.0124 0.0433
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Echinococcus granulosus RUN 0.002 0.0018 0.0017
Brugia malayi hypothetical protein 0.0018 0.0009 0.0028
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0063 0.0385
Loa Loa (eye worm) intermediate filament protein 0.0086 0.0239 0.0837
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0045 0.01 0.0098
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0331 0.3786
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0079 0.0216
Toxoplasma gondii PAN domain-containing protein 0.0016 0.0003 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0009 0.0008
Loa Loa (eye worm) doublecortin family protein 0.002 0.0018 0.0058
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0028 0.0042 0.0144
Onchocerca volvulus 0.0056 0.0136 0.0415
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0174 0.0607
Onchocerca volvulus 0.0056 0.0136 0.0415
Schistosoma mansoni polycystin 1-related 0.002 0.0018 0.0038
Echinococcus granulosus leukotriene A 4 hydrolase 0.024 0.0755 0.0753
Onchocerca volvulus 0.0091 0.0256 0.0784
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0081 0.0221
Onchocerca volvulus 0.0056 0.0136 0.0415
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0028
Echinococcus multilocularis lamin 0.0086 0.0239 0.0237
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0053 0.0642
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0081 0.2445
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0079 0.0078
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0063 0.076
Schistosoma mansoni hypothetical protein 0.0423 0.1368 0.3153
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0076 0.0263
Toxoplasma gondii microneme protein MIC2 0.0056 0.0136 0.1663
Plasmodium vivax thrombospondin-related anonymous protein 0.0056 0.0136 0.3689
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Echinococcus multilocularis serotonin transporter 0.0016 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0083 0.0189
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0018 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0079 0.0216
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0079 0.1573
Onchocerca volvulus 0.003 0.0049 0.0145
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.0076 0.0075
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0056 0.0136 0.6465
Trichomonas vaginalis rotamase, putative 0.0035 0.0066 0.0173
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Brugia malayi phosphofructokinase 0.0114 0.0331 0.116
Onchocerca volvulus 0.0019 0.0013 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0009 0.0008
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0009 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0331 0.0995
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Schistosoma mansoni hypothetical protein 0.002 0.0018 0.0038
Echinococcus granulosus slit 2 protein 0.0052 0.0124 0.0123
Schistosoma mansoni hypothetical protein 0.0056 0.0136 0.0311
Schistosoma mansoni axis inhibition protein axin 0.004 0.0083 0.0189
Brugia malayi laminin-like protein K08C7.3 precursor 0.0052 0.0124 0.0433
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0076 0.0263
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.0076 0.0172
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Echinococcus granulosus dnaJ subfamily B 0.0423 0.1368 0.1366
Onchocerca volvulus 0.0016 0.0003 0.0003
Schistosoma mansoni ap endonuclease 0.0039 0.0081 0.0183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0076 0.0075
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.021 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.0366 0.0364
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0052 0.0124 0.0283
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0013 0.0041
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0128 0.0293
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0067 0.2031
Schistosoma mansoni rotamase 0.0035 0.0066 0.0148
Toxoplasma gondii microneme protein, putative 0.0016 0.0003 0.0039
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.0076 0.0075
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Brugia malayi nuclear hormone receptor 0.0018 0.0009 0.0028
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0009 0.0018
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0018 0.0017
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.0076 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0053 0.0134
Toxoplasma gondii subtilisin SUB12 0.0016 0.0003 0.0039
Schistosoma mansoni hypothetical protein 0.0056 0.0136 0.0311
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0048 0.5436
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Schistosoma mansoni coup transcription factor 0.0038 0.0076 0.0172
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0082 0.3845
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0052 0.0124 0.0433
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0174 0.0172
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.0076 0.0263
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0079 0.0078
Loa Loa (eye worm) glutamate receptor 0.0036 0.0071 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.0076 0.0263
Echinococcus multilocularis neurogenic locus notch protein 0.0052 0.0124 0.0123
Schistosoma mansoni axis inhibition protein axin 0.004 0.0083 0.0189
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.0076 0.0228
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Schistosoma mansoni hypothetical protein 0.0045 0.01 0.0226
Toxoplasma gondii kringle domain-containing protein 0.0025 0.0032 0.0396
Loa Loa (eye worm) PAN domain-containing protein 0.0016 0.0003 0.0006
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0013 0.0041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0081 0.1623
Loa Loa (eye worm) hypothetical protein 0.004 0.0084 0.0291
Schistosoma mansoni sodium-dependent amino acid transporter 0.0016 0.0002 0.0002
Loa Loa (eye worm) PAN domain-containing protein 0.0016 0.0003 0.0006
Brugia malayi conserved hypotetical protein 0.0018 0.0009 0.0028
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0063 0.1018
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0041 0.009
Echinococcus granulosus neurogenic locus notch protein 0.0052 0.0124 0.0123
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.0227 0.071 0.2498
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.0076 0.0075
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0083 0.0082
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0079 0.018
Brugia malayi hypothetical protein 0.0039 0.008 0.0275
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0003
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0083 0.0082
Echinococcus granulosus pikachurin 0.0052 0.0124 0.0123
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0083 0.0229
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0331 0.116
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0067 0.2031
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0083 0.0229
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Echinococcus multilocularis lamin dm0 0.0086 0.0239 0.0237
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0104 0.0297 0.0681
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.026 0.082 1
Onchocerca volvulus 0.0025 0.0032 0.0093
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0331 0.116
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0013 0.0027
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0124 0.0366 0.1284
Toxoplasma gondii aldehyde dehydrogenase 0.026 0.082 1
Brugia malayi MH2 domain containing protein 0.0227 0.071 0.2498
Echinococcus granulosus lamin dm0 0.0086 0.0239 0.0237
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0079 0.0274
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0009 0.0022
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0013 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0067 0.0178
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0045 0.01 0.0346
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0048 0.0589
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.0076 0.0263
Brugia malayi Cytochrome P450 family protein 0.0073 0.0193 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0083 0.0229
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0154 0.1872
Mycobacterium ulcerans epimerase 0.002 0.0018 0.0105
Brugia malayi hypothetical protein 0.002 0.0018 0.0058
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0266 0.0841 0.0839
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0013 0.0012
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Toxoplasma gondii microneme protein MIC17A 0.0016 0.0003 0.0039
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0331 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Brugia malayi Sulfatase family protein 0.0018 0.001 0.0028
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0083 0.0288
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.0076 0.0263
Brugia malayi intermediate filament protein 0.0086 0.0239 0.0837
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0053
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0331 0.0329
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0058
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0079 0.979
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0013 0.0012
Onchocerca volvulus 0.0019 0.0013 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0009 0.0018
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0081 0.0879
Schistosoma mansoni hypothetical protein 0.0039 0.008 0.018
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0288
Schistosoma mansoni regulator of G protein signaling 0.004 0.0083 0.0189
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0097
Onchocerca volvulus 0.0019 0.0013 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0076 0.0263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0056 0.0136 0.0475
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0083 0.0288
Echinococcus multilocularis slit 2 protein 0.0052 0.0124 0.0123
Onchocerca volvulus 0.0056 0.0136 0.0415
Loa Loa (eye worm) hypothetical protein 0.0097 0.0274 0.0959
Brugia malayi Latrophilin receptor protein 2 0.0045 0.01 0.0346
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0274
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0083 0.0189
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0041 0.0279
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0029 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0083 0.0189
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0034 0.0864
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.026 0.082 0.0819
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.0076 0.0263
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0174 0.0607
Brugia malayi Cation transporter family protein 0.0019 0.0013 0.0041
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0174 0.4734
Brugia malayi ecdysone receptor 0.0018 0.0009 0.0028
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Onchocerca volvulus 0.0016 0.0003 0.0003
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0083 0.0082
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.026 0.082 0.0819
Onchocerca volvulus 0.0016 0.0003 0.0003
Schistosoma mansoni rab6-interacting 0.002 0.0018 0.0038
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0013 0.0041
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0048 0.0165
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0288
Onchocerca volvulus 0.005 0.0119 0.036
Brugia malayi hypothetical protein 0.004 0.0083 0.0288
Brugia malayi nuclear receptor NHR-88 0.0018 0.0009 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0193 0.0676
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0056 0.0136 0.3689
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0081 0.1383
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0083 0.0082
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0013 0.0012
Brugia malayi 6-phosphofructokinase 0.0114 0.0331 0.116
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0017 0.0035
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0053 0.243
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0002 0.0001
Echinococcus granulosus tissue type plasminogen activator 0.0025 0.0032 0.0031
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.0818
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0058
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0076 0.0172
Loa Loa (eye worm) CUTiclin-Like family member 0.0056 0.0136 0.0475
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0013 0.0012
Schistosoma mansoni laminin gamma-3 chain 0.0052 0.0124 0.0283
Mycobacterium ulcerans hypothetical protein 0.002 0.0018 0.0105
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.1368 0.1366
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.0076 0.0075
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0003
Brugia malayi Cation transporter family protein 0.0019 0.0013 0.0041
Schistosoma mansoni metabotropic glutamate receptor 0.0077 0.0209 0.0478
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0091 0.0315
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Leishmania major hypothetical protein, conserved 0.0027 0.0041 0.0105
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0079 0.0078
Brugia malayi hypothetical protein 0.0056 0.0136 0.0475
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0083 0.0082
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0083 0.0082
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Schistosoma mansoni hypothetical protein 0.0025 0.0032 0.0071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0076 0.0263
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0057 0.0147
Toxoplasma gondii microneme protein MIC4 0.0016 0.0003 0.0039
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0038 0.0076 0.0075
Schistosoma mansoni cpg binding protein 0.003 0.0049 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0839 0.2761 0.2759
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0018 0.0435
Schistosoma mansoni regulator of G protein signaling 0.004 0.0083 0.0189
Schistosoma mansoni regulator of G protein signaling 0.004 0.0083 0.0189
Schistosoma mansoni lamin 0.0086 0.0239 0.0548
Brugia malayi steroid hormone receptor 0.0038 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Onchocerca volvulus 0.0016 0.0003 0.0003
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0018 0.0017
Mycobacterium ulcerans endonuclease IV 0.0078 0.021 0.2469
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.0076 0.0263
Onchocerca volvulus 0.0016 0.0003 0.0003
Onchocerca volvulus 0.0019 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0045 0.01 0.0346
Brugia malayi Zona pellucida-like domain containing protein 0.0056 0.0136 0.0475
Schistosoma mansoni alpha-glucosidase 0.0136 0.0405 0.0932
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0081 0.028
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0013 0.0012
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0013 0.0041
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0045 0.01 0.0098
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0081 0.3788
Echinococcus granulosus FTZ F1 alpha 0.0038 0.0076 0.0075
Toxoplasma gondii PAN domain-containing protein 0.0016 0.0003 0.0039
Onchocerca volvulus Putative nachr subunit 0.0019 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0078 0.021 0.0734
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0053 0.1386
Loa Loa (eye worm) hypothetical protein 0.0247 0.0779 0.2739
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.0076 0.0172
Loa Loa (eye worm) hypothetical protein 0.004 0.0084 0.0291
Echinococcus granulosus geminin 0.0175 0.0537 0.0536
Echinococcus granulosus metabotropic glutamate receptor 2 0.0077 0.0209 0.0207
Schistosoma mansoni hypothetical protein 0.0045 0.01 0.0226
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0076 0.0075
Brugia malayi Calcitonin receptor-like protein seb-1 0.0141 0.0423 0.1488
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0041 0.1856
Echinococcus granulosus intermediate filament protein 0.0086 0.0239 0.0237
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0045 0.01 0.0098
Loa Loa (eye worm) hypothetical protein 0.0052 0.0124 0.0433
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0009 0.0008
Brugia malayi tailless protein 0.0018 0.0009 0.0028
Schistosoma mansoni thyroid hormone receptor 0.0304 0.0967 0.2228
Loa Loa (eye worm) abnormal epIthelia family member 0.0052 0.0124 0.0433
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0176 0.0403
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0067 0.0231
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0013 0.0041
Onchocerca volvulus 0.0019 0.0013 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0366 0.0841
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0002 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0079 0.0078
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0083 0.0082
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0013 0.0041
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0083 0.0082
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0083 0.0082
Schistosoma mansoni rab6-interacting 0.002 0.0018 0.0038
Echinococcus granulosus serotonin transporter 0.0016 0.0002 0.0001
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0331 0.076
Schistosoma mansoni DNA helicase recq1 0.0029 0.0048 0.0108
Brugia malayi Metabotropic glutamate receptor precursor. 0.0092 0.0259 0.0907
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.0778 0.2738
Schistosoma mansoni hypothetical protein 0.005 0.0119 0.0271
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0013 0.0041
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.066 0.216 0.4982
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.0076 0.0172
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0053 0.243
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0009 0.0028
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0067 0.0066
Schistosoma mansoni hypothetical protein 0.0045 0.01 0.0226
Brugia malayi hypothetical protein 0.0111 0.032 0.1122
Loa Loa (eye worm) hypothetical protein 0.0604 0.1973 0.6951
Onchocerca volvulus 0.0016 0.0003 0.0003
Schistosoma mansoni serine-rich repeat protein 0.0705 0.2311 0.5329
Brugia malayi Zona pellucida-like domain containing protein 0.0056 0.0136 0.0475
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0081 0.5
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0056 0.0136 0.0393
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0053 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0083 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.0076 0.0075
Onchocerca volvulus 0.0019 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.1712 0.5681 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) leukotriene A4 hydrolase 0.024 0.0755 0.2655
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0067 0.0178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0076 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0124 0.0366 0.0841
Onchocerca volvulus 0.002 0.0018 0.0049
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0089 0.0088
Schistosoma mansoni survival motor neuron protein 0.005 0.0119 0.0271
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0079 0.018
Loa Loa (eye worm) hypothetical protein 0.0141 0.0423 0.1488
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0018 0.0017
Schistosoma mansoni cpg binding protein 0.0031 0.0055 0.0123
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0017 0.0053
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0081 0.0079
Brugia malayi hypothetical protein 0.002 0.0018 0.0058
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0079 0.0216
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0083 0.0288
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.0779 0.0777
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0041 0.1856
Schistosoma mansoni aldehyde dehydrogenase 0.026 0.082 0.189
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.0076 0.0263
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0067 0.0178
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0017 0.0053
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0067 0.0178
Brugia malayi Intermediate filament tail domain containing protein 0.0086 0.0239 0.0837
Brugia malayi hypothetical protein 0.0016 0.0002 0.0003
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0104 0.0297 0.0295
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0331 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Brugia malayi 6-phosphofructokinase 0.0114 0.0331 0.116
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0079 0.0595
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus granulosus bloom syndrome protein 0.0042 0.0091 0.0089
Schistosoma mansoni hypothetical protein 0.0045 0.01 0.0226
Brugia malayi PXA domain containing protein 0.004 0.0083 0.0288
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0009 0.0018
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0081 0.0079
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0013 0.0012
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0079 0.1331
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0003
Brugia malayi Protein kinase domain containing protein 0.0025 0.0032 0.0109
Toxoplasma gondii hypothetical protein 0.0016 0.0002 0.0028
Entamoeba histolytica hypothetical protein 0.0039 0.008 0.2409
Loa Loa (eye worm) serotonin transporter b 0.0016 0.0002 0.0003
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0016 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0083 0.0189
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0053 0.0134
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0056 0.0136 0.0475
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0053 0.1593
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0056 0.0136 0.0475
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0029 0.0097
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0002 0.0002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0048 0.0165
Toxoplasma gondii microneme protein MIC17C 0.0016 0.0003 0.0039
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0048 0.0047
Echinococcus multilocularis cpg binding protein 0.0031 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Schistosoma mansoni nuclear receptor 0.0018 0.0009 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0053 0.0134
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0288
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0009 0.0018
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0013 0.0012
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0013 0.0012
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0266 0.0841 0.0839
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0063 0.0766
Entamoeba histolytica hypothetical protein, conserved 0.0056 0.0136 0.4124
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0009 0.0008
Brugia malayi Pre-SET motif family protein 0.0862 0.2838 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0048 0.0589
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0013 0.0041
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0045 0.01 0.0098
Echinococcus multilocularis pikachurin 0.0052 0.0124 0.0123
Echinococcus multilocularis GPCR, family 2 0.0045 0.01 0.0098
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0066 0.0226
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0013 0.0012
Echinococcus granulosus lamin 0.0086 0.0239 0.0237
Loa Loa (eye worm) PAN domain-containing protein 0.0016 0.0003 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.0076 0.0075
Onchocerca volvulus 0.0016 0.0003 0.0003
Brugia malayi hypothetical protein 0.0027 0.0041 0.0138
Treponema pallidum hypothetical protein 0.0056 0.0136 0.0236
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0079 0.24
Entamoeba histolytica hypothetical protein 0.0056 0.0136 0.4124
Schistosoma mansoni nuclear receptor 0.0018 0.0009 0.0018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0081 0.1623
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.021 0.2469
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0288
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0009 0.0008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0089 0.0088
Toxoplasma gondii PAN domain-containing protein 0.0016 0.0003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0104 0.0297 0.104
Onchocerca volvulus 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0124 0.0433
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0067 0.1164
Echinococcus multilocularis thyroid hormone receptor alpha 0.0304 0.0967 0.0966
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0032 0.0388
Toxoplasma gondii microneme protein MIC17B 0.0016 0.0003 0.0039
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.008 0.0078
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.024 0.0755 0.1739
Brugia malayi nuclear receptor RXR 0.002 0.0017 0.0053
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0048 0.0165
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0041 0.0279
Echinococcus multilocularis voltage dependent calcium channel subunit 0.3001 1 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0009 0.0008
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0079 0.0078
Loa Loa (eye worm) CUTiclin family member 0.0056 0.0136 0.0475
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0067 0.0178
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0366 0.0364
Schistosoma mansoni intermediate filament proteins 0.0086 0.0239 0.0548
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0081 0.0138
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0114 0.033 0.0329
Mycobacterium ulcerans aldehyde dehydrogenase 0.026 0.082 1
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0083 0.0288
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0041 0.0497
Loa Loa (eye worm) glutamate receptor 0.0092 0.0259 0.0907
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0056 0.0136 0.1663
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0067 0.0178
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0083 0.0288
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Loa Loa (eye worm) hypothetical protein 0.0052 0.0124 0.0433
Loa Loa (eye worm) RGS-3 protein 0.004 0.0083 0.0288
Brugia malayi hypothetical protein 0.0253 0.0798 0.2809
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0002 0.0001
Echinococcus multilocularis tissue type plasminogen activator 0.0025 0.0032 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.0366 0.0364
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0141 0.014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.0076 0.0075
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0002 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0862 0.2838 1
Brugia malayi Cache domain containing protein 0.0604 0.1973 0.6951
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0331 0.0329
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0331 0.0995
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0083 0.0288
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0077 0.0209 0.0207
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Schistosoma mansoni slit 0.0052 0.0124 0.0283
Brugia malayi von Willebrand factor type A domain containing protein 0.0056 0.0136 0.0475
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0013 0.0027
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0141 0.0423 0.1488
Loa Loa (eye worm) DR-78 0.0018 0.0009 0.0028
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.0779 0.0777
Onchocerca volvulus 0.0124 0.0366 0.1124
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0053 0.0134
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0104 0.0297 0.0681
Schistosoma mansoni cell polarity protein 0.0052 0.0124 0.0283
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0003
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0174 0.5251
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0076 0.0172
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0081 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0331 0.116
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0058
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0017 0.0035
Schistosoma mansoni metabotropic glutamate receptor 0.0045 0.01 0.0228
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0013 0.0041
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0009 0.0028
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0141 0.014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.0348 0.0347
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0086 0.0239 0.0837
Schistosoma mansoni regulator of G protein signaling 0.004 0.0083 0.0189
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus multilocularis RUN 0.002 0.0018 0.0017
Brugia malayi nuclear receptor NHR-67 0.0018 0.0009 0.0028
Entamoeba histolytica hypothetical protein 0.004 0.0083 0.2521
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0104 0.0297 0.0295
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0013 0.0012
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0053 0.0642
Onchocerca volvulus 0.0053 0.0128 0.039
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.0447
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0013 0.0041
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0083 0.0082
Brugia malayi von Willebrand Factor 0.0056 0.0136 0.0475
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Onchocerca volvulus 0.0018 0.0009 0.0022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0174 0.0397
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.0076 0.0263
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0056 0.0136 0.6465
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0013 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0331 0.0995
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.021 0.6129
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0083 0.0082
Brugia malayi latrophilin 2 splice variant baaae 0.0097 0.0274 0.0959
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0028
Brugia malayi EGF-like domain containing protein 0.0052 0.0124 0.0433
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0056 0.0136 0.0475
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.008 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0288
Schistosoma mansoni hypothetical protein 0.0097 0.0274 0.0628
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0009 0.0028
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0009 0.0022
Echinococcus granulosus metabotropic glutamate receptor 5 0.0114 0.033 0.0329
Brugia malayi follicle stimulating hormone receptor 0.0247 0.0778 0.2738
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0331 0.3961
Echinococcus multilocularis tumor protein p63 0.0364 0.117 0.1168
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.004 0.0083 0.2521
Toxoplasma gondii PAN domain-containing protein 0.0016 0.0003 0.0039
Brugia malayi Pre-SET motif family protein 0.0124 0.0366 0.1284
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0009 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0366 0.0841
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0002 0.0001
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0083 0.0288
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0083 0.0082
Echinococcus granulosus expressed protein 0.0777 0.2552 0.2551
Loa Loa (eye worm) latrophilin receptor protein 2 0.0045 0.01 0.0346
Entamoeba histolytica hypothetical protein 0.0039 0.008 0.2409
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0057 0.1727
Schistosoma mansoni lipoxygenase 0.0057 0.0141 0.0322
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0053 0.1386
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.0076 0.0228
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0079 0.0078
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0057 0.0827
Entamoeba histolytica hypothetical protein 0.004 0.0083 0.2521
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0016 0.0004 0.0006
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0174 0.0172
Chlamydia trachomatis endonuclease IV 0.0078 0.021 1
Schistosoma mansoni hypothetical protein 0.0175 0.0537 0.1236
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0002 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0479 0.0477
Brugia malayi Kringle domain containing protein 0.0025 0.0032 0.0109
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0038 0.0076 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0053 0.0134
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0174 0.4734
Schistosoma mansoni hypothetical protein 0.0705 0.2311 0.5329
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0013 0.0041
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0084 0.023 0.0804
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0063 0.1899
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0048 0.0047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0013 0.0041
Onchocerca volvulus 0.0016 0.0003 0.0003
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0002 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0053 0.0134
Brugia malayi hypothetical protein 0.0018 0.0009 0.0028
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0013 0.0027
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0013 0.0012
Brugia malayi Steroid receptor seven-up type 2 0.0038 0.0076 0.0263
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0053 0.243
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0105 0.0364
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0002 0.0028
Brugia malayi photoreceptor-specific nuclear receptor 0.0038 0.0076 0.0263
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0366 0.0841
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.1309 0.4334 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.0076 0.0263
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0081 0.028
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0017 0.0015
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0002 0.0001
Onchocerca volvulus 0.0018 0.0009 0.0022
Schistosoma mansoni ap endonuclease 0.0039 0.0081 0.0183
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Echinococcus granulosus collagen alpha 1VII chain 0.0056 0.0136 0.0135
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0083 0.0288
Schistosoma mansoni cpg binding protein 0.0031 0.0055 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.0076 0.0263
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0009 0.0028
Toxoplasma gondii hypothetical protein 0.0016 0.0003 0.0039
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0025 0.0032 0.083
Entamoeba histolytica hypothetical protein 0.0039 0.008 0.2409
Schistosoma mansoni lipoxygenase 0.002 0.0018 0.0038
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0083 0.0189
Echinococcus granulosus tumor protein p63 0.0364 0.117 0.1168
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0105 0.0301 0.0691
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0091 0.0252
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.0076 0.0075
Schistosoma mansoni alpha-glucosidase 0.0136 0.0405 0.0932
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0056 0.0136 0.3689
Schistosoma mansoni thyroid hormone receptor 0.0304 0.0967 0.2228
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0029 0.0097
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0067 0.0231
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0081 0.0221
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0479 0.1683
Toxoplasma gondii exonuclease III APE 0.0039 0.0081 0.0986
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0083 0.0229
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0331 0.076
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0104 0.0297 0.0681
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0083 0.0082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0081 0.2161
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0479 0.0477
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0053
Brugia malayi hypothetical protein 0.0018 0.0009 0.0025
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0018 0.0763
Brugia malayi nuclear receptor NHR-88 0.0038 0.0076 0.0263
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0013 0.0041
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0066 0.0226
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0013 0.0012
Onchocerca volvulus 0.0038 0.0076 0.0228
Schistosoma mansoni aldehyde dehydrogenase 0.026 0.082 0.189
Schistosoma mansoni nAChR subunit 0.0019 0.0013 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0076 0.0263
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0016 0.0002 0.0001
Toxoplasma gondii hypothetical protein 0.0016 0.0003 0.0039
Loa Loa (eye worm) TK/ROR protein kinase 0.0025 0.0032 0.0109
Trichomonas vaginalis set domain proteins, putative 0.0982 0.3237 1
Onchocerca volvulus 0.0016 0.0003 0.0003
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0067 0.044
Entamoeba histolytica elongation factor-2 kinase, putative 0.0056 0.0136 0.4124
Echinococcus multilocularis voltage dependent calcium channel subunit 0.1365 0.4521 0.452
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Schistosoma mansoni lamin 0.0086 0.0239 0.0548
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0331 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.0076 0.0263
Treponema pallidum 76K protein 0.0056 0.0136 0.0236
Entamoeba histolytica hypothetical protein 0.0039 0.008 0.2409
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0174 0.4583
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0475
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0067 0.0178
Brugia malayi PXA domain containing protein 0.004 0.0083 0.0288
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Onchocerca volvulus 0.0056 0.0136 0.0415
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0013 0.0041
Schistosoma mansoni loxhd1 0.002 0.0018 0.0038
Toxoplasma gondii endonuclease IV APN 0.0078 0.021 0.2557
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0018 0.001 0.0023
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0018 0.0049
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0041 0.1059
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.0076 0.0263
Echinococcus granulosus nAChR subunit 0.0019 0.0013 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.0076 0.0172
Plasmodium falciparum cysteine repeat modular protein 1 0.0025 0.0032 0.1455
Mycobacterium ulcerans aldehyde dehydrogenase 0.026 0.082 1
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0105 0.0364
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0081 0.0614
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0028
Loa Loa (eye worm) MH2 domain-containing protein 0.0227 0.071 0.2498
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0028
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0016 0.0002 0.0001
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0016 0.0003 0.0039
Trichomonas vaginalis rotamase, putative 0.0034 0.0063 0.0165
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.008 0.018
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.021 0.5705
Onchocerca volvulus 0.002 0.0018 0.0049
Brugia malayi Doublecortin family protein 0.002 0.0018 0.0058
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0053 0.0642
Schistosoma mansoni hypothetical protein 0.0266 0.0841 0.1937
Brugia malayi PAN domain containing protein 0.0016 0.0003 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0366 0.4461
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0089 0.031
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0017 0.0053
Echinococcus granulosus axis inhibition protein axin 0.004 0.0083 0.0082
Echinococcus granulosus cpg binding protein 0.0031 0.0055 0.0053
Schistosoma mansoni alpha glucosidase 0.0035 0.0067 0.0151
Brugia malayi nuclear receptor RXR 0.0018 0.0009 0.0028
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0057 0.0313
Onchocerca volvulus 0.0056 0.0136 0.0415
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.066 0.2161 0.7614
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0013 0.0012
Brugia malayi Cation transporter family protein 0.0019 0.0013 0.0041
Schistosoma mansoni zinc finger protein 0.0018 0.0009 0.0018

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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