Detailed information for compound 867696

Basic information

Technical information
  • TDR Targets ID: 867696
  • Name: 3-[(4-methylphenyl)sulfonyl-(phenylmethyl)ami no]propanoic acid
  • MW: 333.402 | Formula: C17H19NO4S
  • H donors: 1 H acceptors: 4 LogP: 2.43 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCN(S(=O)(=O)c1ccc(cc1)C)Cc1ccccc1
  • InChi: 1S/C17H19NO4S/c1-14-7-9-16(10-8-14)23(21,22)18(12-11-17(19)20)13-15-5-3-2-4-6-15/h2-10H,11-13H2,1H3,(H,19,20)
  • InChiKey: FNQFFQLKZFPDBL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[benzyl-(4-methylphenyl)sulfonyl-amino]propionic acid
  • ChemDiv3_013029
  • Oprea1_368079
  • 3-[Benzyl-(toluene-4-sulfonyl)-amino]-propionic acid
  • BAS 00443060
  • NSC105659
  • Oprea1_751718

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0056 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-1 0.013 0.1402 0.1767
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0585 0.0585
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.013 0.1402 0.1402
Schistosoma mansoni cpg binding protein 0.003 0.0195 0.0195
Loa Loa (eye worm) transcription factor SMAD2 0.0472 0.5538 0.6979
Loa Loa (eye worm) hypothetical protein 0.0071 0.0691 0.0871
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.038 0.038
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1139 0.1139
Trypanosoma brucei epsilon tubulin 0.0414 0.484 0.6099
Echinococcus granulosus cpg binding protein 0.003 0.0195 0.0195
Schistosoma mansoni tubulin subunit beta 0.067 0.7936 0.7936
Plasmodium falciparum alpha tubulin 1 0.048 0.5634 0.709
Brugia malayi Nuclear hormone receptor E75 0.0059 0.0541 0.0681
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0414 0.484 0.6099
Echinococcus multilocularis mothers against decapentaplegic 6 0.0014 0.0003 0.0003
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0151 0.1651 0.2054
Loa Loa (eye worm) nuclear receptor NHR-67 0.0059 0.0541 0.0681
Plasmodium falciparum thioredoxin reductase 0.0047 0.0399 0.047
Brugia malayi Smad1 0.0032 0.0218 0.0275
Entamoeba histolytica tubulin family protein 0.067 0.7936 1
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0541 0.0541
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0072 0.0122
Schistosoma mansoni Smad4 0.0014 0.0003 0.0003
Plasmodium vivax tubulin beta chain, putative 0.067 0.7936 1
Brugia malayi Heterochromatin protein 1 0.0069 0.0669 0.0842
Mycobacterium ulcerans cell division protein FtsZ 0.018 0.2005 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.013 0.1402 0.1767
Loa Loa (eye worm) alpha-tubulin 0.048 0.5634 0.71
Brugia malayi Tubulin beta chain 0.0234 0.2665 0.3358
Trypanosoma brucei beta tubulin 0.067 0.7936 1
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0399 0.0503
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.0037
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0151 0.1651 0.2081
Loa Loa (eye worm) tubulin alpha chain 0.048 0.5634 0.71
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1128 0.4341
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Loa Loa (eye worm) tubulin alpha-3 chain 0.0246 0.2799 0.3527
Echinococcus multilocularis lamin dm0 0.0027 0.0154 0.0154
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0071 0.0691 0.0691
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.013 0.1402 0.1767
Trichomonas vaginalis tubulin gamma chain, putative 0.0414 0.484 0.6098
Brugia malayi hypothetical protein 0.0016 0.0025 0.0032
Leishmania major beta tubulin 0.067 0.7936 1
Mycobacterium ulcerans hypothetical protein 0.0036 0.0263 0.1312
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Treponema pallidum cell division protein FtsZ 0.018 0.2005 1
Loa Loa (eye worm) nuclear hormone receptor 0.0059 0.0541 0.0681
Schistosoma mansoni tubulin subunit beta 0.067 0.7936 0.7936
Echinococcus granulosus beta tubulin 0.067 0.7936 0.7936
Chlamydia trachomatis dihydrofolate reductase 0.0044 0.0357 0.4552
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0183 0.2154
Echinococcus multilocularis hypothetical protein 0.048 0.5634 0.5634
Trichomonas vaginalis tubulin gamma chain, putative 0.0414 0.484 0.6098
Entamoeba histolytica hypothetical protein 0.0179 0.1989 0.2453
Loa Loa (eye worm) tubulin alpha 2 0.03 0.3459 0.4358
Echinococcus multilocularis Smad4 0.0032 0.0218 0.0218
Leishmania major beta tubulin 0.067 0.7936 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0218 0.0275
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0183 0.0227
Echinococcus multilocularis Tubulin alpha 1 chain 0.048 0.5634 0.5634
Trypanosoma brucei epsilon tubulin 0.0414 0.484 0.6099
Echinococcus multilocularis dihydrofolate reductase 0.0044 0.0357 0.0357
Echinococcus granulosus chromobox protein 1 0.0069 0.0669 0.0669
Echinococcus multilocularis transcription factor eb 0.0107 0.1129 0.1129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.013 0.1402 0.1767
Brugia malayi p25-alpha family protein 0.0364 0.4237 0.5338
Loa Loa (eye worm) pax transcription factor protein 2 0.0483 0.5665 0.7138
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0059 0.0541 0.0541
Brugia malayi Nuclear hormone receptor E75 0.0059 0.0541 0.0681
Entamoeba histolytica tubulin family protein 0.067 0.7936 1
Echinococcus granulosus CREB binding protein 0.0104 0.1093 0.1093
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.1139 0.1435
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Mycobacterium ulcerans epimerase 0.002 0.0072 0.036
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0399 0.0399
Trichomonas vaginalis tubulin epsilon chain, putative 0.067 0.7936 1
Trypanosoma brucei alpha tubulin 0.048 0.5634 0.71
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.038 0.038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0263 0.0263
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1139 0.1431
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0336 0.0419
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0027 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0056 0.0056
Echinococcus multilocularis chromobox protein 1 0.0069 0.0669 0.0669
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0072 0.036
Echinococcus granulosus tubulin gamma 1 chain 0.0414 0.484 0.484
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0332
Echinococcus granulosus tubulin alpha chain 0.048 0.5634 0.5634
Trichomonas vaginalis tubulin beta chain, putative 0.048 0.5634 0.7098
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0183 0.0198
Loa Loa (eye worm) thymidylate synthase 0.0107 0.1123 0.1416
Brugia malayi PAS domain containing protein 0.0048 0.0415 0.0523
Brugia malayi hypothetical protein 0.0179 0.1989 0.2506
Schistosoma mansoni transcription factor LCR-F1 0.0179 0.1989 0.1989
Leishmania major alpha tubulin 0.048 0.5634 0.71
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1139 0.1431
Echinococcus granulosus flap endonuclease 1 0.0026 0.0143 0.0143
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0062 0.0585 0.0737
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0106 0.0133
Brugia malayi hypothetical protein 0.0071 0.0691 0.0871
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0056 0.0071
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0562 0.0708
Schistosoma mansoni lamin 0.0027 0.0154 0.0154
Echinococcus multilocularis nuclear receptor nhr 48 0.0059 0.0541 0.0541
Brugia malayi beta-tubulin, identical 0.067 0.7936 1
Echinococcus granulosus tubulin alpha 1C chain 0.048 0.5634 0.5634
Toxoplasma gondii beta tubulin 0.067 0.7936 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.1273 0.4898
Loa Loa (eye worm) alpha-tubulin isotype 2 0.03 0.3459 0.4358
Schistosoma mansoni Smad4 0.0014 0.0003 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0027 0.0034
Brugia malayi nuclear receptor NHR-67 0.0059 0.0541 0.0681
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0133 0.0134
Echinococcus multilocularis tubulin alpha 1C chain 0.048 0.5634 0.5634
Echinococcus granulosus CREB binding protein 0.0017 0.003 0.003
Brugia malayi tubulin alpha-2 chain 0.048 0.5634 0.71
Echinococcus multilocularis jun protein 0.0084 0.0841 0.0841
Echinococcus granulosus tubulin subunit beta 0.067 0.7936 0.7936
Echinococcus multilocularis neuropeptide s receptor 0.0464 0.5446 0.5446
Entamoeba histolytica tubulin alpha-1 chain 0.048 0.5634 0.7079
Echinococcus multilocularis Tubulin beta 2C chain 0.067 0.7936 0.7936
Schistosoma mansoni tubulin subunit delta 0.018 0.2005 0.2005
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.03 0.3459 0.4356
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0585 0.0737
Echinococcus multilocularis tubulin alpha chain 0.048 0.5634 0.5634
Giardia lamblia Beta tubulin 0.067 0.7936 1
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0151 0.1651 0.2081
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0059 0.0541 0.0541
Brugia malayi bZIP transcription factor family protein 0.0084 0.0841 0.106
Echinococcus multilocularis Tubulin beta 2C chain 0.067 0.7936 0.7936
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1128 0.4341
Trichomonas vaginalis tubulin alpha chain, putative 0.067 0.7936 1
Echinococcus multilocularis tubulin alpha 3 chain 0.048 0.5634 0.5634
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0263 0.0332
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.048 0.5634 0.7098
Loa Loa (eye worm) tubulin alpha 2 0.03 0.3459 0.4358
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0059 0.0541 0.0541
Schistosoma mansoni tubulin subunit beta 0.067 0.7936 0.7936
Echinococcus granulosus intermediate filament protein 0.0027 0.0154 0.0154
Leishmania major cytochrome p450-like protein 0.0023 0.0106 0.0133
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1139 0.1374
Loa Loa (eye worm) Smad1 0.0032 0.0218 0.0275
Loa Loa (eye worm) hypothetical protein 0.0071 0.0691 0.0871
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0218 0.0218
Onchocerca volvulus 0.0059 0.0541 0.0949
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0197 0.0197
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Echinococcus multilocularis Tubulin alpha 1 chain 0.048 0.5634 0.5634
Echinococcus granulosus lamin 0.0027 0.0154 0.0154
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0044 0.0357 0.1781
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0045 0.0053
Echinococcus multilocularis Tubulin beta 2C chain 0.067 0.7936 0.7936
Trichomonas vaginalis tubulin beta chain, putative 0.0234 0.2665 0.3355
Plasmodium falciparum tubulin beta chain 0.067 0.7936 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0263 0.0332
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0143 0.018
Loa Loa (eye worm) hypothetical protein 0.0149 0.1628 0.2052
Trichomonas vaginalis tubulin beta-1 chain, putative 0.018 0.2005 0.2524
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0263 0.0328
Onchocerca volvulus 0.0483 0.5665 1
Leishmania major hypothetical protein, conserved 0.0025 0.0133 0.0168
Leishmania major beta tubulin 0.067 0.7936 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0183 0.0198
Brugia malayi conserved hypotetical protein 0.0059 0.0541 0.0681
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0059 0.0541 0.0681
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0332
Leishmania major alpha tubulin 0.048 0.5634 0.71
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0183 0.0227
Schistosoma mansoni alpha tubulin 0.048 0.5634 0.5634
Mycobacterium leprae Probable lipase LipE 0.0036 0.0263 0.1312
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.1596 0.1596
Echinococcus granulosus tumor protein p63 0.0337 0.3899 0.3899
Echinococcus multilocularis Tubulin beta 2C chain 0.067 0.7936 0.7936
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1128 0.4341
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0143 0.018
Trichomonas vaginalis tubulin alpha chain, putative 0.0414 0.484 0.6098
Trichomonas vaginalis tubulin, putative 0.0234 0.2665 0.3355
Loa Loa (eye worm) tubulin beta chain 0.067 0.7936 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0403 0.0507
Brugia malayi nuclear receptor NHR-88 0.013 0.1402 0.1767
Schistosoma mansoni chromobox protein 0.0069 0.0669 0.0669
Mycobacterium ulcerans endonuclease IV 0.0076 0.0753 0.3753
Echinococcus multilocularis CREB binding protein 0.0073 0.0709 0.0709
Trypanosoma brucei alpha tubulin 0.048 0.5634 0.71
Mycobacterium tuberculosis Conserved protein 0.0036 0.0263 0.1012
Schistosoma mansoni thyroid hormone receptor 0.0255 0.2918 0.2918
Schistosoma mansoni single-minded 0.0048 0.0415 0.0415
Mycobacterium tuberculosis Hypothetical protein 0.0051 0.0445 0.1712
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.013 0.1402 0.1402
Entamoeba histolytica tubulin alpha chain, putative 0.048 0.5634 0.7079
Brugia malayi Flap endonuclease-1 0.0026 0.0143 0.018
Toxoplasma gondii beta-1 tubulin, putative 0.067 0.7936 1
Trypanosoma cruzi alpha tubulin, putative 0.048 0.5634 0.71
Leishmania major epsilon tubulin, putative 0.0414 0.484 0.6099
Brugia malayi beta-lactamase 0.0036 0.0263 0.0332
Loa Loa (eye worm) DR-78 0.0059 0.0541 0.0681
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Schistosoma mansoni cpg binding protein 0.0029 0.0175 0.0175
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0364 0.0459
Trichomonas vaginalis tubulin alpha chain, putative 0.0234 0.2665 0.3355
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0176 0.0176
Trypanosoma cruzi tubulin delta chain 0.018 0.2005 0.2527
Loa Loa (eye worm) dihydrofolate reductase 0.0044 0.0357 0.045
Leishmania major beta tubulin 0.067 0.7936 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.046 0.0579
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0027 0.0034
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0027 0.0103
Echinococcus multilocularis Tubulin beta 2C chain 0.067 0.7936 0.7936
Loa Loa (eye worm) isocitrate dehydrogenase 0.0062 0.0585 0.0737
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Trichomonas vaginalis tubulin, putative 0.067 0.7936 1
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.018 0.2005 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.1346 0.1346
Schistosoma mansoni nuclear receptor 0.0059 0.0541 0.0541
Schistosoma mansoni retinoid-x-receptor (RXR) 0.013 0.1402 0.1402
Echinococcus multilocularis Tubulin alpha 1 chain 0.048 0.5634 0.5634
Echinococcus granulosus tubulin alpha chain 0.048 0.5634 0.5634
Schistosoma mansoni hypothetical protein 0.0179 0.1989 0.1989
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0027 0.0034
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.1273 0.4898
Brugia malayi Steroid receptor seven-up type 2 0.013 0.1402 0.1767
Trichomonas vaginalis conserved hypothetical protein 0.018 0.2005 0.2524
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0585 0.0737
Onchocerca volvulus Bile acid receptor homolog 0.013 0.1402 0.2471
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0071 0.0691 0.0691
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.03 0.0524
Brugia malayi Isocitrate dehydrogenase 0.0062 0.0585 0.0737
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0183 0.0161
Brugia malayi MH2 domain containing protein 0.0032 0.0218 0.0275
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0364 0.0364
Echinococcus granulosus alpha tubulin 0.048 0.5634 0.5634
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0263 0.0263
Trichomonas vaginalis set domain proteins, putative 0.0237 0.269 0.3387
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0045 0.0053
Schistosoma mansoni tubulin subunit beta 0.067 0.7936 0.7936
Trypanosoma cruzi epsilon tubulin, putative 0.0414 0.484 0.6099
Loa Loa (eye worm) hypothetical protein 0.0149 0.1628 0.2052
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0133 0.0134
Loa Loa (eye worm) BEN-1 protein 0.067 0.7936 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0027 0.0134
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.0067
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0263 0.1012
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0107 0.1123 0.1415
Loa Loa (eye worm) hypothetical protein 0.0071 0.0691 0.0871
Brugia malayi TAZ zinc finger family protein 0.0104 0.1093 0.1377
Trichomonas vaginalis tubulin beta chain, putative 0.048 0.5634 0.7098
Brugia malayi Cytochrome P450 family protein 0.0023 0.0106 0.0133
Leishmania major beta tubulin 0.067 0.7936 1
Brugia malayi MH1 domain containing protein 0.0032 0.0218 0.0275
Trypanosoma brucei beta tubulin 0.067 0.7936 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0183 0.0227
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0027 0.0134
Leishmania major beta tubulin 0.067 0.7936 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1139 0.1435
Echinococcus granulosus transcription factor eb 0.0107 0.1129 0.1129
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0263 0.0332
Brugia malayi Pre-SET motif family protein 0.0208 0.2343 0.2953
Loa Loa (eye worm) MH2 domain-containing protein 0.0014 0.0003 0.0004
Loa Loa (eye worm) p25-alpha family protein 0.0364 0.4237 0.5338
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0669 0.0839
Onchocerca volvulus 0.003 0.0198 0.0344
Loa Loa (eye worm) hypothetical protein 0.048 0.5634 0.71
Leishmania major beta tubulin 0.067 0.7936 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.1139 0.438
Loa Loa (eye worm) MH1 domain-containing protein 0.0014 0.0003 0.0004
Schistosoma mansoni smad1 5 8 and 0.0032 0.0218 0.0218
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0027 0.0034
Trypanosoma brucei tubulin gamma chain 0.0414 0.484 0.6099
Echinococcus granulosus Tubulin alpha 1 chain 0.048 0.5634 0.5634
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0133 0.0168
Echinococcus multilocularis CREB binding protein 0.0017 0.003 0.003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.0037
Trichomonas vaginalis tubulin beta chain, putative 0.048 0.5634 0.7098
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0056 0.0071
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0263 0.1312
Brugia malayi Tubulin alpha chain 0.048 0.5634 0.71
Brugia malayi MH1 domain containing protein 0.0018 0.0045 0.0056
Brugia malayi photoreceptor-specific nuclear receptor 0.013 0.1402 0.1767
Loa Loa (eye worm) steroid hormone receptor 0.013 0.1402 0.1767
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0585 0.0585
Echinococcus granulosus single minded 2 0.0036 0.0263 0.0263
Echinococcus granulosus Tubulin beta 2C chain 0.067 0.7936 0.7936
Brugia malayi hypothetical protein 0.0071 0.0691 0.0871
Echinococcus granulosus tubulin epsilon chain 0.0414 0.484 0.484
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0133 0.0168
Leishmania major alpha tubulin 0.048 0.5634 0.71
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0841 0.0841
Loa Loa (eye worm) MH2 domain-containing protein 0.0472 0.5538 0.6979
Echinococcus granulosus Nuclear hormone receptor HR96 0.0059 0.0541 0.0541
Schistosoma mansoni tubulin subunit beta 0.067 0.7936 0.7936
Brugia malayi Cytochrome P450 family protein 0.0052 0.046 0.0579
Giardia lamblia Epsilon tubulin 0.018 0.2005 0.2501
Echinococcus granulosus chromobox protein 1 0.0069 0.0669 0.0669
Schistosoma mansoni intermediate filament proteins 0.0027 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.03 0.0345
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0133 0.0168
Loa Loa (eye worm) hypothetical protein 0.0081 0.0813 0.1025
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0133 0.0168
Echinococcus granulosus tubulin delta chain 0.018 0.2005 0.2005
Brugia malayi Tubulin alpha-2 chain 0.048 0.5634 0.71
Leishmania major beta tubulin 0.067 0.7936 1
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0753 0.0918
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0263 0.1312
Echinococcus multilocularis tumor protein p63 0.0337 0.3899 0.3899
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0143 0.0111
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0027 0.0034
Echinococcus multilocularis beta tubulin 0.067 0.7936 0.7936
Schistosoma mansoni thyroid hormone receptor 0.0255 0.2918 0.2918
Loa Loa (eye worm) alpha-tubulin 0.048 0.5634 0.71
Trypanosoma cruzi zeta tubulin, putative 0.018 0.2005 0.2527
Loa Loa (eye worm) beta-lactamase 0.0036 0.0263 0.0332
Loa Loa (eye worm) BEN-1 protein 0.067 0.7936 1
Echinococcus multilocularis tubulin alpha 0.0414 0.484 0.484
Echinococcus granulosus tubulin alpha 3 chain 0.048 0.5634 0.5634
Leishmania major beta tubulin 0.067 0.7936 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.013 0.1402 0.1767
Brugia malayi nuclear receptor RXR 0.0071 0.0691 0.0871
Echinococcus multilocularis tubulin alpha 1C chain 0.048 0.5634 0.5634
Trypanosoma brucei zeta tubulin, putative 0.018 0.2005 0.2527
Mycobacterium tuberculosis Probable reductase 0.0107 0.1128 0.4341
Echinococcus multilocularis CREB binding protein 0.0017 0.003 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.013 0.1402 0.1767
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0045 0.0053
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0218 0.0218
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0218 0.0218
Loa Loa (eye worm) tubulin beta-2A chain 0.067 0.7936 1
Brugia malayi tailless protein 0.0059 0.0541 0.0681
Loa Loa (eye worm) hypothetical protein 0.0049 0.0425 0.0536
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.013 0.1402 0.1767
Echinococcus granulosus muscleblind protein 0.0149 0.1628 0.1628
Loa Loa (eye worm) phosphofructokinase 0.0108 0.1139 0.1435
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1139 0.1431
Brugia malayi steroid hormone receptor 0.013 0.1402 0.1767
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.018 0.2005 0.2527
Trichomonas vaginalis tubulin epsilon chain, putative 0.048 0.5634 0.7098
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0263 0.0328
Toxoplasma gondii endonuclease IV APN 0.0076 0.0753 0.0948
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0027 0.003
Schistosoma mansoni nuclear hormone receptor 0.013 0.1402 0.1402
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.1139 0.5678
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0197 0.0248
Leishmania major beta tubulin 0.067 0.7936 1
Brugia malayi glutathione reductase 0.0047 0.0399 0.0503
Echinococcus granulosus Tubulin beta 2C chain 0.067 0.7936 0.7936
Echinococcus multilocularis peroxisome assembly protein 26 0.048 0.5634 0.5634
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Onchocerca volvulus 0.0029 0.0175 0.0304
Onchocerca volvulus TPPP family protein homolog 0.0364 0.4237 0.7477
Brugia malayi thymidylate synthase 0.0107 0.1123 0.1416
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0106 0.0133
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0263 0.1312
Loa Loa (eye worm) hypothetical protein 0.003 0.0197 0.0248
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.038 0.038
Brugia malayi 6-phosphofructokinase 0.0108 0.1139 0.1435
Leishmania major alpha tubulin 0.048 0.5634 0.71
Echinococcus multilocularis lamin 0.0027 0.0154 0.0154
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0263 0.1012
Brugia malayi isocitrate dehydrogenase 0.0062 0.0585 0.0737
Plasmodium vivax tubulin gamma chain, putative 0.0414 0.484 0.6086
Loa Loa (eye worm) hypothetical protein 0.0163 0.1795 0.2262
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0154 0.0194
Schistosoma mansoni alpha tubulin 0.048 0.5634 0.5634
Brugia malayi hypothetical protein 0.0025 0.0133 0.0168
Brugia malayi Tubulin beta-1 chain 0.067 0.7936 1
Echinococcus multilocularis FTZ F1 alpha 0.013 0.1402 0.1402
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0154 0.0194
Plasmodium falciparum alpha tubulin 2 0.048 0.5634 0.709
Brugia malayi Pax transcription factor protein 2 0.0483 0.5665 0.7138
Echinococcus granulosus lamin dm0 0.0027 0.0154 0.0154
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0071
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0841 0.0841
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0062 0.0585 0.0737
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1128 0.5628
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.1139 0.1139
Brugia malayi nuclear hormone receptor 0.0059 0.0541 0.0681
Giardia lamblia Gamma tubulin 0.0414 0.484 0.6086
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0183 0.0231
Schistosoma mansoni zinc finger protein 0.0059 0.0541 0.0541
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0045 0.0053
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.1596 0.2012
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0669 0.0839
Entamoeba histolytica hypothetical protein 0.0179 0.1989 0.2453
Schistosoma mansoni tubulin subunit gamma 0.0414 0.484 0.484
Leishmania major gamma-tubulin 0.0414 0.484 0.6099
Leishmania major beta tubulin 0.067 0.7936 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0263 0.0328
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0107 0.1123 0.1123
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0107 0.1129 0.1423
Brugia malayi Cytochrome P450 family protein 0.0023 0.0106 0.0133
Brugia malayi alpha-tubulin 0.048 0.5634 0.71
Loa Loa (eye worm) acetyltransferase 0.0146 0.1596 0.2012
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1139 0.1431
Brugia malayi nuclear hormone receptor 0.013 0.1402 0.1767
Plasmodium vivax tubulin alpha chain, putative 0.048 0.5634 0.709
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0263 0.0263
Loa Loa (eye worm) beta-tubulin 0.067 0.7936 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0045 0.0053
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0062 0.0585 0.0706
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0059 0.0541 0.0949
Plasmodium falciparum tubulin gamma chain 0.0414 0.484 0.6086
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.03 0.0345
Schistosoma mansoni smad 0.0014 0.0003 0.0003
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1139 0.1139
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0027 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.013 0.1402 0.1402
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Trypanosoma brucei zeta tubulin 0.018 0.2005 0.2527
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0201
Schistosoma mansoni nuclear receptor 0.0059 0.0541 0.0541
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1139 0.1435
Echinococcus multilocularis tubulin alpha chain 0.048 0.5634 0.5634
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0808 0.9595 0.9595
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-31 0.013 0.1402 0.1767
Echinococcus multilocularis musashi 0.0027 0.0154 0.0154
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0541 0.0541
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0194
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0263 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-25 0.013 0.1402 0.1767
Echinococcus multilocularis tubulin alpha chain 0.048 0.5634 0.5634
Leishmania major alpha tubulin 0.048 0.5634 0.71
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0235 0.2676 0.3372
Trichomonas vaginalis tubulin, putative 0.0234 0.2665 0.3355
Toxoplasma gondii ABC1 family protein 0.0036 0.0263 0.0332
Trypanosoma brucei trypanothione reductase 0.0047 0.0399 0.0503
Echinococcus multilocularis tubulin delta chain 0.018 0.2005 0.2005
Brugia malayi Tubulin alpha chain 0.018 0.2005 0.2527
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0218 0.0218
Brugia malayi Nuclear hormone receptor-like 1 0.013 0.1402 0.1767
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0332
Mycobacterium ulcerans thymidylate synthase 0.0107 0.1123 0.5603
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0246 0.2799 0.3524
Schistosoma mansoni tubulin subunit alpha 0.048 0.5634 0.5634
Echinococcus multilocularis tubulin subunit TubB 0.048 0.5634 0.5634
Schistosoma mansoni smad1 5 8 and 0.0032 0.0218 0.0218
Loa Loa (eye worm) tubulin alpha 2 0.0066 0.0623 0.0785
Leishmania major beta tubulin 0.067 0.7936 1
Giardia lamblia Beta tubulin 0.067 0.7936 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0059 0.0541 0.0681
Trypanosoma brucei alpha tubulin 0.048 0.5634 0.71
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0753 0.2895
Brugia malayi Dihydrofolate reductase 0.0044 0.0357 0.045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0045 0.0053
Echinococcus multilocularis chromobox protein 1 0.0069 0.0669 0.0669
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.1139 0.5678
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0106 0.0526
Loa Loa (eye worm) tubulin alpha chain 0.048 0.5634 0.71
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0071
Onchocerca volvulus 0.0049 0.0425 0.0745
Loa Loa (eye worm) hypothetical protein 0.0246 0.2799 0.3527
Brugia malayi orphan nuclear receptor NR2E1 0.0059 0.0541 0.0681
Brugia malayi Cell division protein ftsZ 0.018 0.2005 0.2527
Brugia malayi Nuclear hormone receptor family member nhr-19 0.013 0.1402 0.1767
Brugia malayi hypothetical protein 0.0059 0.0541 0.0681
Onchocerca volvulus 0.0027 0.0154 0.0267
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0179 0.1989 0.1989
Brugia malayi ecdysteroid receptor 0.013 0.1402 0.1767
Echinococcus granulosus beta tubulin 0.067 0.7936 0.7936
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Echinococcus multilocularis muscleblind protein 1 0.0149 0.1628 0.1628
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0027 0.0034
Brugia malayi Tubulin gamma chain 0.0414 0.484 0.6099
Echinococcus granulosus tubulin beta 1 chain 0.067 0.7936 0.7936
Mycobacterium leprae cell division protein FtsZ 0.018 0.2005 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0197 0.0197
Toxoplasma gondii beta-tubulin, putative 0.067 0.7936 1
Giardia lamblia Alpha-tubulin 0.048 0.5634 0.709
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0183 0.0227
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0263 0.0328
Echinococcus granulosus Tubulin beta 2C chain 0.067 0.7936 0.7936
Trypanosoma brucei beta tubulin 0.067 0.7936 1
Trichomonas vaginalis tubulin beta chain, putative 0.048 0.5634 0.7098
Loa Loa (eye worm) hypothetical protein 0.0039 0.03 0.0378
Schistosoma mansoni tubulin subunit alpha 0.048 0.5634 0.5634
Leishmania major trypanothione reductase 0.0047 0.0399 0.0503
Leishmania major beta tubulin 0.067 0.7936 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0263 0.1012
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0263 0.0332
Schistosoma mansoni dihydrofolate reductase 0.0044 0.0357 0.0357
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0056
Echinococcus multilocularis smad 0.0032 0.0218 0.0218
Brugia malayi beta-lactamase family protein 0.0036 0.0263 0.0332
Echinococcus granulosus nuclear receptor nhr 48 0.0059 0.0541 0.0541
Echinococcus granulosus tubulin subunit TubB 0.048 0.5634 0.5634
Leishmania major beta tubulin 0.067 0.7936 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0045 0.0053
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0062 0.0585 0.0585
Brugia malayi Nuclear hormone receptor family member nhr-49 0.013 0.1402 0.1767
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.0067
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0072 0.0091
Brugia malayi follicle stimulating hormone receptor 0.0235 0.2676 0.3372
Onchocerca volvulus 0.0237 0.269 0.4745
Brugia malayi dihydrofolate reductase family protein 0.0044 0.0357 0.045
Schistosoma mansoni hypothetical protein 0.0841 1 1
Brugia malayi nuclear receptor NHR-88 0.0059 0.0541 0.0681
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.038 0.038
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0151 0.1651 0.2081
Schistosoma mansoni hypothetical protein 0.0841 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.013 0.1402 0.1402
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0263 0.0263
Leishmania major delta tubulin, putative 0.018 0.2005 0.2527
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0263 0.1012
Onchocerca volvulus 0.0107 0.1123 0.1979
Echinococcus granulosus neuropeptide s receptor 0.0464 0.5446 0.5446
Echinococcus granulosus mothers against decapentaplegic 6 0.0014 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Brugia malayi MH1 domain containing protein 0.0032 0.0218 0.0275
Onchocerca volvulus 0.0036 0.0263 0.0459
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.1139 0.1139
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0062 0.0585 0.0706
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0009 0.0007
Plasmodium falciparum tubulin delta chain, putative 0.018 0.2005 0.2501
Echinococcus multilocularis tubulin alpha chain 0.048 0.5634 0.5634
Brugia malayi Nuclear hormone receptor family member nhr-41 0.013 0.1402 0.1767
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0027 0.0034
Plasmodium vivax tubulin alpha chain, putative 0.048 0.5634 0.709
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0183 0.2154
Plasmodium vivax delta tubulin, putative 0.018 0.2005 0.2501
Leishmania major alpha tubulin 0.048 0.5634 0.71
Brugia malayi hypothetical protein 0.0059 0.0541 0.0681
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0062 0.0585 0.0585
Echinococcus granulosus Smad4 0.0032 0.0218 0.0218
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0585 0.0737
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0263 0.0328
Echinococcus granulosus tubulin alpha 3 chain 0.048 0.5634 0.5634
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0151 0.1651 0.2081
Trypanosoma brucei tubulin delta chain 0.018 0.2005 0.2527
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0422 0.0422
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.013 0.1402 0.2471
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0228 0.2589 0.2589
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0056 0.0279
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0004
Brugia malayi hypothetical protein 0.0066 0.0624 0.0786
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0143 0.018
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0183 0.0231
Giardia lamblia Beta tubulin 0.067 0.7936 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Brugia malayi Tubulin beta chain 0.018 0.2005 0.2527
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0056
Brugia malayi MH2 domain containing protein 0.0472 0.5538 0.6979
Echinococcus granulosus thyroid hormone receptor alpha 0.0059 0.0541 0.0541
Leishmania major beta tubulin 0.067 0.7936 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0157 0.1728 0.1728
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0691 0.0871
Schistosoma mansoni tubulin subunit epsilon 0.0414 0.484 0.484
Loa Loa (eye worm) tubulin beta chain 0.018 0.2005 0.2527
Brugia malayi intermediate filament protein 0.0027 0.0154 0.0194
Brugia malayi Tubulin alpha-2 chain 0.048 0.5634 0.71
Echinococcus multilocularis mothers against decapentaplegic 2 0.0014 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0179 0.1989 0.2453
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.013 0.1402 0.1402
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.1643 0.207
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0541 0.0541
Loa Loa (eye worm) hypothetical protein 0.03 0.3459 0.4358
Echinococcus granulosus jun protein 0.0084 0.0841 0.0841
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.26 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0027 0.0034
Schistosoma mansoni hypothetical protein 0.0125 0.1346 0.1346
Trichomonas vaginalis tubulin epsilon chain, putative 0.048 0.5634 0.7098
Echinococcus multilocularis tubulin gamma 1 chain 0.0414 0.484 0.484
Echinococcus multilocularis CREB binding protein 0.0017 0.003 0.003
Brugia malayi phosphofructokinase 0.0108 0.1139 0.1435
Brugia malayi Pre-SET motif family protein 0.003 0.0197 0.0248
Mycobacterium tuberculosis Cell division protein FtsZ 0.018 0.2005 0.7713
Schistosoma mansoni Smad4 0.0032 0.0218 0.0218
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0027 0.0027
Echinococcus granulosus tubulin beta 4A class IVa 0.067 0.7936 0.7936
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0071 0.0691 0.0691
Plasmodium vivax SET domain protein, putative 0.003 0.0197 0.0215
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.1273 0.4898
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0585 0.0585
Schistosoma mansoni tubulin subunit beta 0.018 0.2005 0.2005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.013 0.1402 0.1767
Schistosoma mansoni retinoic acid receptor RXR 0.0228 0.2589 0.2589
Echinococcus granulosus Tubulin beta 2C chain 0.067 0.7936 0.7936
Mycobacterium ulcerans hypothetical protein 0.002 0.0072 0.036
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0334 0.0334
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0364 0.0427
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0151 0.1651 0.2054
Trypanosoma cruzi beta tubulin, putative 0.067 0.7936 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.013 0.1402 0.1402
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.013 0.1402 0.1402
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0263 0.0332
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0044 0.0357 0.1374
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1139 0.1374
Trypanosoma brucei beta tubulin 0.067 0.7936 1
Leishmania major beta tubulin 0.067 0.7936 1
Onchocerca volvulus 0.0036 0.0269 0.047
Leishmania major alpha tubulin 0.048 0.5634 0.71
Echinococcus multilocularis thymidylate synthase 0.0107 0.1123 0.1123
Brugia malayi nuclear hormone receptor family member nhr-6 0.0059 0.0541 0.0681
Brugia malayi CXXC zinc finger family protein 0.0029 0.0175 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.03 0.0374
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0753 0.0918
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0445 0.0557
Echinococcus granulosus FTZ F1 alpha 0.013 0.1402 0.1402
Echinococcus granulosus peroxisome assembly protein 26 0.048 0.5634 0.5634
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0106 0.0133
Trichomonas vaginalis tubulin beta chain, putative 0.067 0.7936 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0234 0.2665 0.3355
Onchocerca volvulus 0.0042 0.0334 0.0584
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0004 0.0004
Brugia malayi beta-lactamase family protein 0.0036 0.0263 0.0332
Echinococcus granulosus ecdysone induced protein 78C 0.013 0.1402 0.1402
Echinococcus granulosus Tubulin alpha 1 chain 0.048 0.5634 0.5634
Toxoplasma gondii exonuclease III APE 0.0019 0.0056 0.0071
Echinococcus multilocularis muscleblind protein 0.0149 0.1628 0.1628
Echinococcus multilocularis beta tubulin 0.067 0.7936 0.7936
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1139 0.1435
Echinococcus granulosus tubulin alpha 1C chain 0.048 0.5634 0.5634
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0263 0.1312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0056 0.0215
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0336 0.0419
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.013 0.1402 0.1767
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.2343 0.2953
Echinococcus multilocularis cpg binding protein 0.003 0.0195 0.0195
Trichomonas vaginalis tubulin alpha chain, putative 0.0234 0.2665 0.3355
Echinococcus granulosus tubulin alpha 0.0414 0.484 0.484
Brugia malayi Nuclear hormone receptor family member nhr-14 0.013 0.1402 0.1767
Echinococcus multilocularis tubulin epsilon chain 0.0414 0.484 0.484
Echinococcus granulosus neuropeptide receptor A26 0.0464 0.5446 0.5446
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.038 0.038
Leishmania major hypothetical protein, conserved 0.0036 0.0263 0.0332
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0183 0.0227
Loa Loa (eye worm) hypothetical protein 0.0107 0.1123 0.1415
Schistosoma mansoni lamin 0.0027 0.0154 0.0154
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0541 0.0541
Trichomonas vaginalis tubulin epsilon chain, putative 0.067 0.7936 1
Leishmania major alpha tubulin 0.048 0.5634 0.71
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0364 0.0455
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.1526 0.1526
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.013 0.1402 0.1767
Onchocerca volvulus 0.0059 0.0541 0.0949
Trichomonas vaginalis tubulin beta chain, putative 0.048 0.5634 0.7098
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0364 0.0459
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0106 0.0133
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.038 0.038
Onchocerca volvulus 0.0036 0.0263 0.0459
Trypanosoma brucei epsilon tubulin 0.0414 0.484 0.6099
Plasmodium vivax tubulin epsilon chain, putative 0.0414 0.484 0.6086
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0364 0.0455
Mycobacterium ulcerans beta-lactamase 0.0036 0.0263 0.1312
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0059 0.0541 0.0541
Echinococcus multilocularis tubulin, beta 4A class IVa 0.067 0.7936 0.7936
Onchocerca volvulus 0.0234 0.2665 0.4701
Trypanosoma cruzi epsilon tubulin, putative 0.0414 0.484 0.6099
Schistosoma mansoni smad 0.0032 0.0218 0.0218
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0183 0.0231
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0218 0.0218
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0027 0.003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0059 0.0541 0.0541
Loa Loa (eye worm) hypothetical protein 0.003 0.0198 0.025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.013 0.1402 0.1402
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0009 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.013 0.1402 0.1767
Plasmodium falciparum flap endonuclease 1 0.0026 0.0143 0.0147
Trypanosoma cruzi tubulin delta chain 0.018 0.2005 0.2527
Toxoplasma gondii thioredoxin reductase 0.0047 0.0399 0.0503
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0059 0.0541 0.0949
Schistosoma mansoni jun-related protein 0.0068 0.0651 0.0651
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0399 0.0399
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.013 0.1402 0.1767
Loa Loa (eye worm) hypothetical protein 0.0026 0.0148 0.0187
Trichomonas vaginalis tubulin epsilon chain, putative 0.018 0.2005 0.2524
Brugia malayi hypothetical protein 0.0163 0.1795 0.2262
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Plasmodium falciparum glutathione reductase 0.0047 0.0399 0.047
Plasmodium vivax glutathione reductase, putative 0.0047 0.0399 0.047
Brugia malayi 6-phosphofructokinase 0.0108 0.1139 0.1435
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0044 0.0357 0.1781
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.013 0.1402 0.1402
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.013 0.1402 0.1402
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0399 0.047
Echinococcus granulosus CREB binding protein 0.0066 0.0625 0.0625
Echinococcus multilocularis isocitrate dehydrogenase 0.0062 0.0585 0.0585
Brugia malayi MH2 domain containing protein 0.0032 0.0218 0.0275
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0027 0.0034
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Schistosoma mansoni CREB-binding protein 2 0.0104 0.1093 0.1093
Schistosoma mansoni hypothetical protein 0.0068 0.0651 0.0651
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0143 0.0143
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0062 0.0585 0.0585
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.013 0.1402 0.1767
Loa Loa (eye worm) hypothetical protein 0.0076 0.0753 0.0948
Schistosoma mansoni steroid hormone receptor ad4bp 0.013 0.1402 0.1402
Onchocerca volvulus 0.0027 0.0154 0.0267
Mycobacterium tuberculosis Conserved protein 0.0036 0.0263 0.1012
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0071 0.0691 0.0871
Brugia malayi hypothetical protein 0.0051 0.0445 0.0561
Giardia lamblia Alpha-tubulin 0.048 0.5634 0.709
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Leishmania major alpha tubulin 0.048 0.5634 0.71
Echinococcus granulosus tubulin alpha chain 0.048 0.5634 0.5634
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0263 0.1012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.013 0.1402 0.1402
Schistosoma mansoni tubulin subunit alpha 0.048 0.5634 0.5634
Giardia lamblia Delta tubulin 0.018 0.2005 0.2501
Brugia malayi ecdysone receptor 0.0059 0.0541 0.0681
Schistosoma mansoni tubulin subunit beta 0.067 0.7936 0.7936
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0585 0.0737
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0143 0.018
Entamoeba histolytica tubulin gamma chain 0.0414 0.484 0.6072
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0143 0.0147
Onchocerca volvulus 0.0066 0.0624 0.1096
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0175 0.0221
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.038 0.0479
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.038 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-40 0.013 0.1402 0.1767
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0154 0.0194
Leishmania major alpha tubulin 0.048 0.5634 0.71
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0585 0.0737
Echinococcus granulosus smad 0.0032 0.0218 0.0218
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0263 0.1012
Trypanosoma brucei alpha tubulin 0.048 0.5634 0.71
Brugia malayi Muscleblind-like protein 0.0149 0.1628 0.2052
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0576 0.0576
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0691 0.0691
Brugia malayi chromobox protein homolog 3 0.0039 0.03 0.0378
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0234 0.2665 0.3355
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0179 0.1989 0.1989
Trichomonas vaginalis tubulin beta chain, putative 0.048 0.5634 0.7098
Trypanosoma cruzi tubulin gamma chain 0.0414 0.484 0.6099
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0059 0.0541 0.0541
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.03 0.031
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0004
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0143 0.018
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0263 0.0299
Loa Loa (eye worm) CBP-B 0.0074 0.072 0.0907
Onchocerca volvulus Protein ultraspiracle homolog 0.013 0.1402 0.2471
Onchocerca volvulus 0.0036 0.0263 0.0459
Loa Loa (eye worm) tubulin beta-4 chain 0.067 0.7936 1
Echinococcus multilocularis tubulin alpha 3 chain 0.048 0.5634 0.5634
Leishmania major beta tubulin 0.067 0.7936 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0399 0.1535
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.1596 0.1596
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1139 0.1374
Brugia malayi tubulin alpha chain - mouse 0.048 0.5634 0.71
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0056 0.0071
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0263 0.1012
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0056 0.0037
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0753 0.3753
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0056 0.0071
Echinococcus multilocularis geminin 0.0841 1 1
Loa Loa (eye worm) nuclear factor I 0.0018 0.0045 0.0056
Brugia malayi MH1 domain containing protein 0.0018 0.0045 0.0056
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1128 0.4341
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0183 0.0227
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0143 0.0147
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0072 0.0278
Leishmania major beta tubulin 0.067 0.7936 1
Schistosoma mansoni RAR-like nuclear receptor 0.013 0.1402 0.1402
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0106 0.0133
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0056 0.0147
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Echinococcus multilocularis thyroid hormone receptor alpha 0.0255 0.2918 0.2918
Trichomonas vaginalis tubulin gamma chain, putative 0.067 0.7936 1
Echinococcus multilocularis tubulin alpha chain 0.048 0.5634 0.5634
Chlamydia trachomatis endonuclease IV 0.0076 0.0753 1
Trichomonas vaginalis tubulin gamma chain, putative 0.018 0.2005 0.2524
Schistosoma mansoni alpha tubulin 0.048 0.5634 0.5634
Schistosoma mansoni tubulin subunit alpha 0.018 0.2005 0.2005
Brugia malayi Thioredoxin reductase 0.0047 0.0399 0.0503
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0183 0.079
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.03 0.0374
Echinococcus granulosus Tubulin beta 2C chain 0.067 0.7936 0.7936
Echinococcus granulosus CREB binding protein 0.0017 0.003 0.003
Echinococcus granulosus tubulin alpha chain 0.048 0.5634 0.5634
Loa Loa (eye worm) hypothetical protein 0.013 0.1402 0.1767
Loa Loa (eye worm) glutathione reductase 0.0047 0.0399 0.0503
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0107 0.1123 0.5603
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0027 0.0034
Schistosoma mansoni coup transcription factor 0.013 0.1402 0.1402
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.013 0.1402 0.1402
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0399 0.0503
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0056 0.0056
Schistosoma mansoni smad1 5 8 and 0.0032 0.0218 0.0218
Echinococcus multilocularis tubulin subunit beta 0.067 0.7936 0.7936
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0197 0.0197
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1139 0.1435
Echinococcus granulosus tubulin alpha chain 0.048 0.5634 0.5634
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.1273 0.6351
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.1346 0.1346
Echinococcus granulosus thymidylate synthase 0.0107 0.1123 0.1123
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0183 0.0227
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0062 0.0585 0.225
Loa Loa (eye worm) tubulin gamma chain 0.0414 0.484 0.6099
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0059 0.0541 0.0681
Echinococcus granulosus mothers against decapentaplegic 2 0.0014 0.0003 0.0003
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0104 0.1093 0.1093
Trypanosoma cruzi zeta tubulin, putative 0.018 0.2005 0.2527
Plasmodium falciparum tubulin epsilon chain, putative 0.0414 0.484 0.6086
Echinococcus multilocularis neuropeptide receptor A26 0.0464 0.5446 0.5446
Leishmania major alpha tubulin 0.048 0.5634 0.71
Schistosoma mansoni Tr4/Tr2 (homologue) 0.013 0.1402 0.1402
Loa Loa (eye worm) tubulin alpha-2 chain 0.048 0.5634 0.71
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0059 0.0541 0.0541
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0197 0.0197
Echinococcus granulosus Tubulin alpha 1 chain 0.048 0.5634 0.5634
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0183 0.0198
Loa Loa (eye worm) hypothetical protein 0.0071 0.0691 0.0871
Toxoplasma gondii alpha tubulin TUBA1 0.048 0.5634 0.71
Trypanosoma brucei alpha tubulin, putative 0.0234 0.2665 0.3358
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0071 0.0691 0.0871
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0045 0.0053
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.013 0.1402 0.1402
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0669 0.0842
Trichomonas vaginalis tubulin, putative 0.018 0.2005 0.2524
Brugia malayi hypoxia-induced factor 1 0.015 0.1643 0.207
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.1139 0.5619
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0143 0.0176
Loa Loa (eye worm) tubulin beta-1 chain 0.067 0.7936 1
Entamoeba histolytica hypothetical protein 0.0179 0.1989 0.2453
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0263 0.1012
Schistosoma mansoni chromobox protein 0.0069 0.0669 0.0669
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0027 0.0027
Toxoplasma gondii alpha-tubulin I, putative 0.048 0.5634 0.71
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0218 0.0275
Brugia malayi MH2 domain containing protein 0.0014 0.0003 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0263 0.0263
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0027 0.0134
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0197 0.0197
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0051 0.0445 0.0561
Schistosoma mansoni flap endonuclease-1 0.0023 0.0113 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0106 0.0133
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0107 0.1123 0.4322
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0183 0.0198
Trichomonas vaginalis esterase, putative 0.0036 0.0263 0.0328
Loa Loa (eye worm) hypothetical protein 0.0025 0.0133 0.0168
Trypanosoma brucei beta tubulin 0.0414 0.484 0.6099
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0691 0.0871
Onchocerca volvulus 0.013 0.1402 0.2471
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.018 0.2005 0.2527
Mycobacterium ulcerans lipase LipD 0.0036 0.0263 0.1312
Leishmania major zeta tubulin, putative 0.018 0.2005 0.2527
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.018 0.2005 0.2524
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.013 0.1402 0.1402
Schistosoma mansoni cpg binding protein 0.003 0.0195 0.0195
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0183 0.0198
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.038 0.038
Brugia malayi nuclear receptor RXR 0.0059 0.0541 0.0681
Loa Loa (eye worm) hypothetical protein 0.0059 0.0541 0.0681
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0336 0.0587
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0133 0.0134
Echinococcus multilocularis tubulin beta 1 chain 0.067 0.7936 0.7936
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0753 0.0948
Leishmania major alpha tubulin 0.048 0.5634 0.71
Mycobacterium leprae conserved hypothetical protein 0.002 0.0072 0.036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0332
Schistosoma mansoni hypothetical protein 0.0104 0.1083 0.1083
Brugia malayi mothers against decapentaplegic homolog 3 0.0014 0.0003 0.0004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.013 0.1402 0.1402
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0027 0.0034
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.013 0.1402 0.1402
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0425 0.0425
Schistosoma mansoni nuclear receptor nhr-48 0.0059 0.0541 0.0541
Echinococcus multilocularis ecdysone induced protein 78C 0.013 0.1402 0.1402
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1128 0.4341
Echinococcus granulosus dihydrofolate reductase 0.0044 0.0357 0.0357

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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