Detailed information for compound 876540

Basic information

Technical information
  • TDR Targets ID: 876540
  • Name: methyl 3-[[4-(trifluoromethyl)phenyl]methylca rbamoylamino]benzoate
  • MW: 352.308 | Formula: C17H15F3N2O3
  • H donors: 2 H acceptors: 2 LogP: 3.16 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1cccc(c1)NC(=O)NCc1ccc(cc1)C(F)(F)F
  • InChi: 1S/C17H15F3N2O3/c1-25-15(23)12-3-2-4-14(9-12)22-16(24)21-10-11-5-7-13(8-6-11)17(18,19)20/h2-9H,10H2,1H3,(H2,21,22,24)
  • InChiKey: JCSWSSFXTFNFMC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[[oxo-[[4-(trifluoromethyl)phenyl]methylamino]methyl]amino]benzoic acid methyl ester
  • 3-[[4-(trifluoromethyl)benzyl]carbamoylamino]benzoic acid methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi nuclear hormone receptor 0.0068 0.0082 0.012
Brugia malayi Thioredoxin reductase 0.0056 0.0058 0.0085
Mycobacterium tuberculosis Conserved protein 0.0043 0.0032 0.0018
Schistosoma mansoni histone deacetylase 0.0775 0.1466 0.1895
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.0344 0.0445
Echinococcus multilocularis geminin 0.398 0.7733 0.7733
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0155 0.0253 0.0371
Echinococcus multilocularis CREB binding protein 0.0094 0.0133 0.0133
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0048 0.0048
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0029 0.0006 0.0007
Trichomonas vaginalis tubulin gamma chain, putative 0.1927 0.3718 0.5454
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0013 0.0019
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0043 0.0034 0.0049
Brugia malayi tailless protein 0.0068 0.0082 0.012
Toxoplasma gondii beta-tubulin, putative 0.3512 0.6818 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0047
Brugia malayi beta-tubulin, identical 0.3512 0.6818 1
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0041 0.0029 0.0029
Trypanosoma brucei alpha tubulin 0.2545 0.4927 0.7226
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0019 0.0025
Echinococcus granulosus histone deacetylase 6 0.0377 0.0686 0.0887
Loa Loa (eye worm) hypoxia-induced factor 1 0.0325 0.0584 0.0857
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0041 0.0029 0.0038
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.012 0.0176
Leishmania major beta tubulin 0.3512 0.6818 1
Loa Loa (eye worm) CBP-B 0.0095 0.0135 0.0197
Entamoeba histolytica tubulin alpha chain, putative 0.2545 0.4927 0.7226
Onchocerca volvulus 0.0068 0.0082 0.0273
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0002 0.0004
Loa Loa (eye worm) alpha-tubulin isotype 2 0.1708 0.329 0.4826
Trypanosoma cruzi alpha tubulin, putative 0.2545 0.4927 0.7226
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0034 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0082 0.0106
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0837 0.1586 0.2326
Entamoeba histolytica tubulin family protein 0.3512 0.6818 1
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0837 0.1586 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0068 0.0082 0.0106
Trypanosoma brucei histone deacetylase 4 0.0377 0.0686 0.1005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0075 0.011
Loa Loa (eye worm) transcription factor SMAD2 0.2066 0.399 0.5851
Leishmania major ATP-dependent phosphofructokinase 0.0128 0.02 0.0294
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0155 0.0253 0.0253
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0032 0.0018
Giardia lamblia Beta tubulin 0.3512 0.6818 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0142 0.0226 0.1263
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0058
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0338 0.0611 0.079
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0027 0.0002 0.0004
Giardia lamblia Histone deacetylase 0.0775 0.1466 0.2143
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0043 0.0034 0.0034
Echinococcus granulosus thymidylate synthase 0.0127 0.0197 0.0255
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0063 0.0072 0.0105
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.002 0.0026
Mycobacterium tuberculosis Conserved protein 0.0043 0.0032 0.0018
Schistosoma mansoni alpha tubulin 0.2545 0.4927 0.6371
Echinococcus granulosus cpg binding protein 0.0036 0.0019 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0155 0.0253 0.0371
Brugia malayi nuclear receptor RXR 0.0087 0.012 0.0176
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0019 0.0029
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Brugia malayi Gooseberry protein 0.003 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0059 0.0087
Schistosoma mansoni aryl hydrocarbon receptor 0.0107 0.0158 0.0204
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0017 0.0025
Schistosoma mansoni jumonji domain containing protein 0.0123 0.019 0.0246
Echinococcus multilocularis histone deacetylase 6 0.0377 0.0686 0.0686
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0142 0.0226 0.1263
Echinococcus granulosus Smad4 0.0141 0.0224 0.029
Leishmania major beta tubulin 0.3512 0.6818 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0032 0.0018
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.048 0.0887 0.1147
Loa Loa (eye worm) hypothetical protein 0.0258 0.0453 0.0665
Brugia malayi intermediate filament protein 0.0062 0.007 0.0103
Toxoplasma gondii DNA topoisomerase 2, putative 0.0063 0.0072 0.0105
Trichomonas vaginalis tubulin, putative 0.109 0.2082 0.3053
Trypanosoma brucei cytochrome P450, putative 0.0043 0.0033 0.0049
Brugia malayi Nuclear hormone receptor E75 0.0068 0.0082 0.012
Leishmania major cytochrome p450-like protein 0.0043 0.0033 0.0049
Onchocerca volvulus 0.109 0.2082 0.6934
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0155 0.0253 0.0327
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0029 0.0006 0.0008
Onchocerca volvulus 0.1561 0.3002 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0043 0.0034 0.0027
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0009 0.0014
Brugia malayi Cell division protein ftsZ 0.0837 0.1586 0.2326
Loa Loa (eye worm) 6-phosphofructokinase 0.0128 0.02 0.0294
Brugia malayi hypothetical protein 0.0697 0.1312 0.1924
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0009 0.0014
Entamoeba histolytica tubulin gamma chain 0.1927 0.3718 0.5454
Brugia malayi Histone deacetylase family protein 0.0377 0.0686 0.1005
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0041 0.0029 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0155 0.0253 0.0253
Trichomonas vaginalis tubulin gamma chain, putative 0.0837 0.1586 0.2326
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0279 0.0495 0.0726
Schistosoma mansoni dihydrofolate reductase 0.0052 0.005 0.0065
Leishmania major beta tubulin 0.3512 0.6818 1
Echinococcus granulosus CREB binding protein 0.0131 0.0206 0.0266
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0338 0.0611 0.0611
Trypanosoma brucei epsilon tubulin 0.1927 0.3718 0.5454
Echinococcus granulosus tubulin alpha 3 chain 0.2545 0.4927 0.6371
Loa Loa (eye worm) intermediate filament protein 0.0062 0.007 0.0103
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0338 0.0611 0.079
Echinococcus multilocularis tubulin subunit beta 0.3512 0.6818 0.6818
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0134 0.021 0.0272
Trichomonas vaginalis tubulin beta chain, putative 0.2545 0.4927 0.7226
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0155 0.0253 0.0327
Echinococcus multilocularis beta tubulin 0.3512 0.6818 0.6818
Brugia malayi hypothetical protein 0.0068 0.0082 0.012
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0179 0.0298 0.0438
Trypanosoma cruzi histone deacetylase, putative 0.0377 0.0686 0.1005
Onchocerca volvulus 0.0068 0.0082 0.0273
Trichomonas vaginalis DNA topoisomerase II, putative 0.0063 0.0072 0.0105
Echinococcus granulosus Nuclear hormone receptor HR96 0.0068 0.0082 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0032 0.0047
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1927 0.3718 0.5454
Leishmania major beta tubulin 0.3512 0.6818 1
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0041 0.0029 0.0038
Schistosoma mansoni nuclear receptor 0.0068 0.0082 0.0106
Brugia malayi MH1 domain containing protein 0.0078 0.0101 0.0149
Leishmania major histone deacetylase, putative 0.0775 0.1466 0.2149
Giardia lamblia Histone acetyltransferase GCN5 0.0129 0.0201 0.0286
Toxoplasma gondii thioredoxin reductase 0.0056 0.0058 0.0085
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0092 0.0119
Echinococcus multilocularis tubulin, beta 4A class IVa 0.3512 0.6818 0.6818
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0058
Echinococcus granulosus smad 0.0141 0.0224 0.029
Echinococcus multilocularis nuclear receptor nhr 48 0.0068 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0697 0.1312 0.1924
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0778 0.147 0.2156
Brugia malayi Steroid receptor seven-up type 2 0.0155 0.0253 0.0371
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0029 0.0006 0.0006
Schistosoma mansoni alpha tubulin 0.2545 0.4927 0.6371
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0338 0.0611 0.3737
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.0344 0.0344
Loa Loa (eye worm) BEN-1 protein 0.3512 0.6818 1
Echinococcus multilocularis tubulin subunit TubB 0.2545 0.4927 0.4927
Toxoplasma gondii histone deacetylase HDAC1 0.0377 0.0686 0.1005
Loa Loa (eye worm) Smad1 0.0141 0.0224 0.0329
Trypanosoma cruzi PAB1-binding protein , putative 0.0298 0.0532 0.078
Brugia malayi follicle stimulating hormone receptor 0.0279 0.0495 0.0726
Brugia malayi hypothetical protein 0.0298 0.0532 0.078
Brugia malayi 'Paired box' domain containing protein 0.003 0.0008 0.0011
Brugia malayi alpha-tubulin 0.2545 0.4927 0.7226
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0338 0.0611 0.0896
Onchocerca volvulus 0.003 0.0008 0.0025
Entamoeba histolytica hypothetical protein 0.0697 0.1312 0.1924
Onchocerca volvulus Histone deacetylase 10 homolog 0.0258 0.0453 0.1509
Leishmania major delta tubulin, putative 0.0837 0.1586 0.2326
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0011
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0075 0.0097
Echinococcus granulosus histone deacetylase 0.0377 0.0686 0.0887
Loa Loa (eye worm) isocitrate dehydrogenase 0.0338 0.0611 0.0896
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0336 0.0606 0.0889
Brugia malayi Isocitrate dehydrogenase 0.0338 0.0611 0.0896
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0047
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0127 0.0198 0.1084
Loa Loa (eye worm) alpha-tubulin 0.2545 0.4927 0.7226
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0029 0.0006 0.0007
Echinococcus granulosus tubulin alpha chain 0.2545 0.4927 0.6371
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0005
Brugia malayi MH1 domain containing protein 0.0141 0.0224 0.0329
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Echinococcus multilocularis chromobox protein 1 0.0082 0.011 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0298 0.0532 0.078
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0002 0.0004
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0017 0.0025
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0032 0.0018
Echinococcus granulosus GPCR family 2 0.0051 0.0048 0.0063
Echinococcus granulosus mothers against decapentaplegic 2 0.0063 0.0072 0.0093
Echinococcus multilocularis dihydrofolate reductase 0.0052 0.005 0.005
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0087 0.012 0.012
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.002 0.0026
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0338 0.0611 0.0896
Trypanosoma cruzi epsilon tubulin, putative 0.1927 0.3718 0.5454
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0155 0.0253 0.0371
Trichomonas vaginalis histone deacetylase, putative 0.0775 0.1466 0.2149
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0179 0.0298 0.0438
Onchocerca volvulus Bile acid receptor homolog 0.0155 0.0253 0.0842
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0011
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0837 0.1586 0.2326
Plasmodium falciparum histone deacetylase 1 0.0775 0.1466 0.2149
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0127 0.0198 0.1237
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0048 0.0071
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0006 0.0008
Plasmodium vivax JmjC domain containing protein 0.0033 0.0013 0.002
Trichomonas vaginalis histone deacetylase, putative 0.0775 0.1466 0.2149
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.002 0.0029
Trypanosoma brucei DNA topoisomerase ii 0.0049 0.0045 0.0067
Schistosoma mansoni tubulin subunit beta 0.3512 0.6818 0.8818
Echinococcus multilocularis thymidylate synthase 0.0127 0.0197 0.0197
Brugia malayi Nuclear hormone receptor E75 0.0068 0.0082 0.012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0039 0.0131
Schistosoma mansoni lamin 0.0062 0.007 0.0091
Chlamydia trachomatis DNA gyrase subunit B 0.0034 0.0016 0.0656
Trypanosoma cruzi DNA topoisomerase II, putative 0.0056 0.0059 0.0087
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0179 0.0298 0.0438
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0029 0.0006 0.0008
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0091 0.0126 0.0185
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0017 0.0766
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0155 0.0253 0.0327
Entamoeba histolytica phosphofructokinase, putative 0.0128 0.02 0.0294
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0142 0.0226 0.1412
Loa Loa (eye worm) zinc finger protein 0.0303 0.0541 0.0794
Toxoplasma gondii exonuclease III APE 0.0043 0.0034 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0019 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0006 0.0008
Schistosoma mansoni flap endonuclease-1 0.0028 0.0003 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0161 0.0263 0.0386
Echinococcus granulosus tubulin subunit TubB 0.2545 0.4927 0.6371
Brugia malayi jmjC domain containing protein 0.0125 0.0194 0.0285
Echinococcus multilocularis tubulin alpha 3 chain 0.2545 0.4927 0.4927
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0128 0.02 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0017 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0019 0.0025
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0143 0.0228 0.0334
Echinococcus granulosus tubulin alpha 1C chain 0.2545 0.4927 0.6371
Plasmodium falciparum histone deacetylase, putative 0.0377 0.0686 0.1005
Leishmania major isocitrate dehydrogenase, putative 0.0041 0.0029 0.0043
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0775 0.1466 0.2149
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1708 0.329 0.4826
Schistosoma mansoni nuclear receptor 0.0068 0.0082 0.0106
Trypanosoma cruzi tubulin delta chain 0.0837 0.1586 0.2326
Leishmania major hypothetical protein, conserved 0.0043 0.0032 0.0047
Echinococcus multilocularis histone deacetylase 3 0.0775 0.1466 0.1466
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0043 0.0034 0.0049
Trypanosoma cruzi histone deacetylase, putative 0.0377 0.0686 0.1005
Mycobacterium tuberculosis Conserved protein 0.0043 0.0032 0.0018
Echinococcus multilocularis jun protein 0.0099 0.0143 0.0143
Brugia malayi Pre-SET motif family protein 0.0247 0.0431 0.0632
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0029 0.0006 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0304 0.0544 0.0703
Toxoplasma gondii beta tubulin 0.3512 0.6818 1
Echinococcus multilocularis tubulin alpha chain 0.2545 0.4927 0.4927
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0013 0.0017
Leishmania major beta tubulin 0.3512 0.6818 1
Trichomonas vaginalis tubulin alpha chain, putative 0.109 0.2082 0.3053
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0775 0.1466 0.2149
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0029 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0047
Plasmodium falciparum histone deacetylase 2 0.0377 0.0686 0.1005
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0017 0.0025
Toxoplasma gondii alpha tubulin TUBA1 0.2545 0.4927 0.7226
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0091 0.0126 0.0781
Schistosoma mansoni histone deacetylase 4 5 0.0377 0.0686 0.0887
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Loa Loa (eye worm) histone deacetylase 0.0377 0.0686 0.1005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0008 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0017 0.0025
Echinococcus multilocularis mothers against decapentaplegic 6 0.0063 0.0072 0.0072
Toxoplasma gondii isocitrate dehydrogenase 0.0338 0.0611 0.0896
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0043 0.0033 0.0024
Leishmania major epsilon tubulin, putative 0.1927 0.3718 0.5454
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0029 0.0006 0.0006
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0017 0.0025
Schistosoma mansoni hypothetical protein 0.398 0.7733 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.007 0.0103
Echinococcus multilocularis Tubulin beta 2C chain 0.3512 0.6818 0.6818
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0063 0.0072 0.0093
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Onchocerca volvulus 0.0043 0.0032 0.0107
Echinococcus multilocularis transfer RNA-Lys 0.0078 0.0101 0.0101
Echinococcus granulosus paired box gene 3/7 (eyeless, eyegone, twin of eyeless) 0.003 0.0008 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0697 0.1312 0.1697
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.002 0.0029
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0202 0.0344 0.0505
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0056 0.0059 0.0087
Plasmodium vivax tubulin gamma chain, putative 0.1927 0.3718 0.5454
Trypanosoma cruzi DNA topoisomerase II, putative 0.0056 0.0059 0.0087
Plasmodium falciparum tubulin beta chain 0.3512 0.6818 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0068 0.0082 0.012
Trypanosoma brucei beta tubulin 0.3512 0.6818 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0015 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0034 0.0049
Trypanosoma cruzi histone deacetylase, putative 0.0258 0.0453 0.0665
Echinococcus multilocularis histone deacetylase 7 0.0377 0.0686 0.0686
Echinococcus multilocularis Tubulin alpha 1 chain 0.2545 0.4927 0.4927
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0063 0.0072 0.024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.002 0.0029
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0272 0.048 0.0621
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Trypanosoma brucei beta tubulin 0.3512 0.6818 1
Plasmodium falciparum alpha tubulin 2 0.2545 0.4927 0.7226
Echinococcus granulosus lamin dm0 0.0062 0.007 0.0091
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0013 0.0017
Echinococcus granulosus transcription factor eb 0.0338 0.0609 0.0788
Loa Loa (eye worm) tubulin alpha-2 chain 0.2545 0.4927 0.7226
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0032 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0013 0.002
Plasmodium vivax tubulin beta chain, putative 0.3512 0.6818 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0775 0.1466 0.2149
Schistosoma mansoni Smad4 0.0063 0.0072 0.0093
Toxoplasma gondii histone deacetylase HDAC4 0.0258 0.0453 0.0665
Loa Loa (eye worm) hypothetical protein 0.1708 0.329 0.4826
Brugia malayi Muscleblind-like protein 0.0637 0.1195 0.1753
Leishmania major beta tubulin 0.3512 0.6818 1
Brugia malayi dihydrofolate reductase family protein 0.0052 0.005 0.0074
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0082 0.0082
Loa Loa (eye worm) steroid hormone receptor 0.0155 0.0253 0.0371
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0013 0.0017
Schistosoma mansoni chromobox protein 0.0082 0.011 0.0142
Loa Loa (eye worm) glutathione reductase 0.0056 0.0058 0.0085
Giardia lamblia Beta tubulin 0.3512 0.6818 1
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0179 0.0298 0.0438
Echinococcus granulosus intermediate filament protein 0.0062 0.007 0.0091
Schistosoma mansoni transcription factor LCR-F1 0.0697 0.1312 0.1697
Loa Loa (eye worm) hypothetical protein 0.0161 0.0263 0.0386
Echinococcus granulosus tubulin delta chain 0.0837 0.1586 0.2051
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0022 0.0029
Trichomonas vaginalis tubulin beta chain, putative 0.3512 0.6818 1
Brugia malayi beta-lactamase family protein 0.0043 0.0032 0.0047
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0131 0.0206 0.0266
Loa Loa (eye worm) vab-3 0.003 0.0008 0.0011
Echinococcus multilocularis GPCR, family 2 0.0051 0.0048 0.0048
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0013 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0032 0.0047
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0009 0.0014
Echinococcus granulosus histone deacetylase 6 0.0403 0.0736 0.0952
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0032 0.0188
Loa Loa (eye worm) acetyltransferase 0.048 0.0887 0.1301
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0048 0.0071
Echinococcus multilocularis lamin 0.0062 0.007 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0155 0.0253 0.0371
Brugia malayi Zinc finger, C2H2 type family protein 0.0303 0.0541 0.0794
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0008 0.0008
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0013 0.0013
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0013 0.0017
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0099 0.0143 0.0143
Leishmania major protein kinase, putative 0.0027 0.0002 0.0004
Brugia malayi TAZ zinc finger family protein 0.0131 0.0206 0.0302
Echinococcus granulosus tubulin alpha chain 0.2545 0.4927 0.6371
Giardia lamblia Alpha-tubulin 0.2545 0.4927 0.7223
Brugia malayi vab-3 gene. 0.003 0.0008 0.0011
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0043 0.0034 0.0041
Schistosoma mansoni histone deacetylase 1 2 3 0.0258 0.0453 0.0586
Trypanosoma brucei histone deacetylase 1 0.0775 0.1466 0.2149
Brugia malayi orphan nuclear receptor NR2E1 0.0068 0.0082 0.012
Brugia malayi Pax transcription factor protein 2 0.1561 0.3002 0.4403
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.0344 0.0445
Schistosoma mansoni hypothetical protein 0.398 0.7733 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0075 0.011
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0013 0.002
Echinococcus multilocularis lamin dm0 0.0062 0.007 0.007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0062 0.007 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0032 0.0047
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0013 0.002
Schistosoma mansoni paired box protein pax-6 0.003 0.0008 0.001
Toxoplasma gondii histone deacetylase HDAC3 0.0775 0.1466 0.2149
Schistosoma mansoni hypothetical protein 0.0116 0.0176 0.0228
Echinococcus granulosus TGF beta signal transducer SmadC 0.0141 0.0224 0.029
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0011
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0014 0.0021
Brugia malayi Tubulin beta chain 0.109 0.2082 0.3053
Echinococcus granulosus histone deacetylase 6 0.0377 0.0686 0.0887
Brugia malayi Tubulin alpha chain 0.2545 0.4927 0.7226
Onchocerca volvulus 0.0034 0.0015 0.0051
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0099 0.0143 0.0185
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.002 0.0026
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0013 0.0017
Brugia malayi Probable isocitrate dehydrogenase 0.0041 0.0029 0.0043
Loa Loa (eye worm) hypothetical protein 0.0096 0.0138 0.0202
Schistosoma mansoni tubulin subunit alpha 0.2545 0.4927 0.6371
Brugia malayi Tubulin alpha chain 0.0837 0.1586 0.2326
Echinococcus multilocularis histone deacetylase 6 0.0377 0.0686 0.0686
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0029 0.0006 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.0155 0.0253 0.0371
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0128 0.02 0.1168
Leishmania major beta tubulin 0.3512 0.6818 1
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0032 0.0047
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0091 0.0126 0.0185
Echinococcus multilocularis peroxisome assembly protein 26 0.2545 0.4927 0.4927
Giardia lamblia Delta tubulin 0.0837 0.1586 0.2319
Echinococcus multilocularis chromobox protein 1 0.0082 0.011 0.011
Loa Loa (eye worm) DR-78 0.0068 0.0082 0.012
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0013 0.0017
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0063 0.0072 0.0105
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0013 0.002
Onchocerca volvulus 0.0043 0.0032 0.0107
Echinococcus granulosus jun protein 0.0099 0.0143 0.0185
Echinococcus multilocularis Smad4 0.0141 0.0224 0.0224
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0127 0.0197 0.1231
Schistosoma mansoni zinc finger protein 0.0068 0.0082 0.0106
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0002 0.0004
Leishmania major beta tubulin 0.3512 0.6818 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Loa Loa (eye worm) tubulin beta-2A chain 0.3512 0.6818 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Echinococcus multilocularis muscleblind protein 1 0.0637 0.1195 0.1195
Trichomonas vaginalis tubulin epsilon chain, putative 0.2545 0.4927 0.7226
Echinococcus granulosus lamin 0.0062 0.007 0.0091
Onchocerca volvulus 0.0114 0.0172 0.0572
Trichomonas vaginalis chromobox protein, putative 0.005 0.0046 0.0068
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0013 0.002
Brugia malayi Tubulin beta-1 chain 0.3512 0.6818 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0068 0.0082 0.0082
Trypanosoma cruzi histone deacetylase, putative 0.0258 0.0453 0.0665
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0029 0.0006 0.0008
Schistosoma mansoni hypothetical protein 0.0149 0.024 0.031
Echinococcus granulosus phd:f box containing protein 0.0033 0.0013 0.0017
Loa Loa (eye worm) thymidylate synthase 0.0127 0.0197 0.0289
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Trypanosoma brucei alpha tubulin 0.2545 0.4927 0.7226
Schistosoma mansoni cpg binding protein 0.0034 0.0015 0.002
Schistosoma mansoni coup transcription factor 0.0155 0.0253 0.0327
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.02 0.0294
Echinococcus multilocularis musashi 0.0062 0.007 0.007
Leishmania major beta tubulin 0.3512 0.6818 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0075 0.011
Entamoeba histolytica hypothetical protein 0.0697 0.1312 0.1924
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0032 0.0032
Echinococcus granulosus CREB binding protein 0.0086 0.0116 0.015
Treponema pallidum cell division protein FtsZ 0.0837 0.1586 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0029 0.0006 0.0007
Trypanosoma brucei zeta tubulin, putative 0.0837 0.1586 0.2326
Brugia malayi 6-phosphofructokinase 0.0128 0.02 0.0294
Loa Loa (eye worm) dihydrofolate reductase 0.0052 0.005 0.0074
Schistosoma mansoni histone deacetylase 4 5 0.0377 0.0686 0.0887
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0058
Schistosoma mansoni hypothetical protein 0.011 0.0164 0.0212
Entamoeba histolytica histone deacetylase, putative 0.0775 0.1466 0.2149
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0068 0.0082 0.0273
Echinococcus granulosus histone acetyltransferase KAT2B 0.0464 0.0857 0.1108
Trichomonas vaginalis histone deacetylase, putative 0.0775 0.1466 0.2149
Loa Loa (eye worm) histone deacetylase 1 0.0775 0.1466 0.2149
Mycobacterium tuberculosis Hypothetical protein 0.006 0.0067 0.0242
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0034 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0046 0.0059
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0149 0.024 0.031
Trichomonas vaginalis chromobox protein, putative 0.005 0.0046 0.0068
Echinococcus granulosus thioredoxin glutathione reductase 0.0056 0.0058 0.0075
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0087 0.012 0.0176
Brugia malayi Cytochrome P450 family protein 0.0043 0.0033 0.0049
Echinococcus granulosus paired box protein pax 6 0.003 0.0008 0.001
Brugia malayi beta-lactamase 0.0043 0.0032 0.0047
Loa Loa (eye worm) nuclear hormone receptor 0.0068 0.0082 0.012
Echinococcus granulosus lysine specific demethylase 5A 0.0125 0.0194 0.0251
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0048 0.0063
Entamoeba histolytica tartrate dehydrogenase, putative 0.0041 0.0029 0.0043
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.002 0.0029
Echinococcus granulosus thyroid hormone receptor alpha 0.0068 0.0082 0.0106
Toxoplasma gondii ABC1 family protein 0.0043 0.0032 0.0047
Loa Loa (eye worm) TOPoisomerase family member 0.0063 0.0072 0.0105
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0123 0.019 0.0246
Leishmania major beta tubulin 0.3512 0.6818 1
Echinococcus granulosus 6 phosphofructokinase 0.0128 0.02 0.0259
Trypanosoma brucei beta tubulin 0.1927 0.3718 0.5454
Echinococcus multilocularis tubulin alpha 1C chain 0.2545 0.4927 0.4927
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0043 0.0034 0.0027
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0014 0.0021
Brugia malayi beta-lactamase family protein 0.0043 0.0032 0.0047
Plasmodium vivax delta tubulin, putative 0.0837 0.1586 0.2326
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0032 0.0047
Plasmodium falciparum tubulin epsilon chain, putative 0.1927 0.3718 0.5454
Loa Loa (eye worm) pax transcription factor protein 2 0.1561 0.3002 0.4403
Giardia lamblia DNA topoisomerase II 0.006 0.0066 0.0089
Echinococcus multilocularis Tubulin beta 2C chain 0.3512 0.6818 0.6818
Leishmania major DNA topoisomerase ii 0.0056 0.0059 0.0087
Echinococcus granulosus Tubulin beta 2C chain 0.3512 0.6818 0.8818
Leishmania major beta tubulin 0.3512 0.6818 1
Schistosoma mansoni tubulin subunit beta 0.3512 0.6818 0.8818
Trichomonas vaginalis tubulin alpha chain, putative 0.1927 0.3718 0.5454
Trichomonas vaginalis tubulin, putative 0.3512 0.6818 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0338 0.0611 0.0611
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0013 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0143 0.0228 0.0334
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0179 0.0298 0.0438
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0052 0.005 0.0302
Echinococcus multilocularis tubulin alpha chain 0.2545 0.4927 0.4927
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0082 0.0106
Loa Loa (eye worm) hypothetical protein 0.0087 0.012 0.0176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0082 0.0106
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0228 0.0295
Loa Loa (eye worm) tubulin alpha chain 0.2545 0.4927 0.7226
Onchocerca volvulus 0.0049 0.0046 0.0153
Schistosoma mansoni unc-13 (munc13) 0.0041 0.0029 0.0038
Brugia malayi 'Paired box' domain containing protein 0.003 0.0008 0.0011
Brugia malayi histone deacetylase 1 (HD1) 0.0775 0.1466 0.2149
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0049 0.0045 0.0067
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0002 0.0004
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.0033 0.0049
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0022 0.0022
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0002 0.0004
Mycobacterium tuberculosis Probable dehydrogenase 0.0127 0.0198 0.1084
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0009 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0013 0.002
Echinococcus granulosus mothers against decapentaplegic 5 0.0141 0.0224 0.029
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0087 0.012 0.0155
Echinococcus granulosus Tubulin alpha 1 chain 0.2545 0.4927 0.6371
Echinococcus granulosus tubulin alpha chain 0.2545 0.4927 0.6371
Plasmodium vivax histone deacetylase, putative 0.0258 0.0453 0.0665
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0155 0.0253 0.0371
Schistosoma mansoni nuclear hormone receptor 0.0155 0.0253 0.0327
Brugia malayi hypothetical protein 0.0087 0.012 0.0176
Plasmodium vivax glutathione reductase, putative 0.0056 0.0058 0.0085
Loa Loa (eye worm) histone deacetylase 11 0.0258 0.0453 0.0665
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0697 0.1312 0.1312
Echinococcus multilocularis transcription factor eb 0.0338 0.0609 0.0609
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0017 0.0017
Mycobacterium leprae cell division protein FtsZ 0.0837 0.1586 1
Trypanosoma cruzi epsilon tubulin, putative 0.1927 0.3718 0.5454
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0155 0.0253 0.0327
Loa Loa (eye worm) hypothetical protein 0.011 0.0164 0.024
Loa Loa (eye worm) hypothetical protein 0.0114 0.0172 0.0252
Echinococcus granulosus chromobox protein 1 0.0082 0.011 0.0142
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0029 0.0006 0.0007
Schistosoma mansoni hypothetical protein 0.0134 0.021 0.0272
Onchocerca volvulus 0.0079 0.0104 0.0347
Schistosoma mansoni histone deacetylase hda2 0.0403 0.0736 0.0952
Entamoeba histolytica DNA topoisomerase II, putative 0.0063 0.0072 0.0105
Echinococcus multilocularis tubulin delta chain 0.0837 0.1586 0.1586
Echinococcus granulosus paired box protein pax 1 0.003 0.0008 0.001
Plasmodium falciparum DNA topoisomerase 2 0.0063 0.0072 0.0105
Schistosoma mansoni Smad4 0.0141 0.0224 0.029
Trichomonas vaginalis tubulin epsilon chain, putative 0.3512 0.6818 1
Trichomonas vaginalis tubulin alpha chain, putative 0.109 0.2082 0.3053
Echinococcus granulosus beta tubulin 0.3512 0.6818 0.8818
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0017 0.0025
Brugia malayi conserved hypotetical protein 0.0068 0.0082 0.012
Trypanosoma brucei histone deacetylase, putative 0.0377 0.0686 0.1005
Brugia malayi Tubulin alpha-2 chain 0.2545 0.4927 0.7226
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0008
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0002 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.2066 0.399 0.5851
Trichomonas vaginalis tubulin, putative 0.109 0.2082 0.3053
Giardia lamblia Gamma tubulin 0.1927 0.3718 0.545
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0017 0.0025
Schistosoma mansoni tubulin subunit beta 0.3512 0.6818 0.8818
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0048 0.0063
Entamoeba histolytica hypothetical protein 0.0697 0.1312 0.1924
Leishmania major beta tubulin 0.3512 0.6818 1
Brugia malayi Nuclear hormone receptor-like 1 0.0155 0.0253 0.0371
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0048 0.0048
Schistosoma mansoni ap endonuclease 0.0043 0.0034 0.0044
Brugia malayi MH2 domain containing protein 0.0063 0.0072 0.0106
Schistosoma mansoni smad1 5 8 and 0.0141 0.0224 0.029
Loa Loa (eye worm) hypothetical protein 0.0087 0.012 0.0176
Schistosoma mansoni ap endonuclease 0.0043 0.0034 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0155 0.0253 0.0327
Schistosoma mansoni tubulin subunit alpha 0.0837 0.1586 0.2051
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0087 0.012 0.0155
Echinococcus multilocularis tubulin alpha chain 0.2545 0.4927 0.4927
Echinococcus multilocularis aryl hydrocarbon receptor 0.0029 0.0006 0.0006
Leishmania major beta tubulin 0.3512 0.6818 1
Echinococcus granulosus tubulin alpha 3 chain 0.2545 0.4927 0.6371
Loa Loa (eye worm) tubulin alpha 2 0.1708 0.329 0.4826
Trichomonas vaginalis conserved hypothetical protein 0.0837 0.1586 0.2326
Echinococcus multilocularis neuropeptide receptor A26 0.0551 0.1026 0.1026
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0029 0.0006 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0019 0.0025
Brugia malayi PAS domain containing protein 0.0105 0.0154 0.0226
Loa Loa (eye worm) hypothetical protein 0.2545 0.4927 0.7226
Brugia malayi Tubulin gamma chain 0.1927 0.3718 0.5454
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0029
Echinococcus granulosus flap endonuclease 1 0.0031 0.0009 0.0012
Brugia malayi hypothetical protein 0.006 0.0067 0.0098
Plasmodium vivax ataxin-2 like protein, putative 0.0298 0.0532 0.078
Echinococcus multilocularis thyroid hormone receptor alpha 0.0304 0.0544 0.0544
Brugia malayi Calcitonin receptor-like protein seb-1 0.0161 0.0263 0.0386
Echinococcus granulosus Nuclear hormone receptor HR96 0.0068 0.0082 0.0106
Plasmodium vivax histone deacetylase 1, putative 0.0775 0.1466 0.2149
Echinococcus granulosus tubulin alpha chain 0.2545 0.4927 0.6371
Chlamydia trachomatis endonuclease IV 0.0091 0.0126 1
Trichomonas vaginalis tubulin gamma chain, putative 0.1927 0.3718 0.5454
Schistosoma mansoni single-minded 0.0105 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Trypanosoma brucei PAB1-binding protein , putative 0.0298 0.0532 0.078
Loa Loa (eye worm) hypothetical protein 0.0119 0.0182 0.0266
Trypanosoma cruzi tubulin gamma chain 0.1927 0.3718 0.5454
Loa Loa (eye worm) hypothetical protein 0.0775 0.1466 0.2149
Brugia malayi phosphofructokinase 0.0128 0.02 0.0294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0155 0.0253 0.0371
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0043 0.0034 0.0049
Schistosoma mansoni 6-phosphofructokinase 0.0128 0.02 0.0259
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0043
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0087 0.012 0.0155
Toxoplasma gondii LsmAD domain-containing protein 0.0298 0.0532 0.078
Echinococcus granulosus histone deacetylase 3 0.0775 0.1466 0.1895
Plasmodium vivax DNA topoisomerase II, putative 0.0063 0.0072 0.0105
Echinococcus granulosus chromobox protein 1 0.0082 0.011 0.0142
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Brugia malayi Smad1 0.0141 0.0224 0.0329
Trypanosoma cruzi tubulin delta chain 0.0837 0.1586 0.2326
Echinococcus granulosus tubulin alpha 1C chain 0.2545 0.4927 0.6371
Echinococcus multilocularis Tubulin beta 2C chain 0.3512 0.6818 0.6818
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0127 0.0197 0.1078
Loa Loa (eye worm) hypothetical protein 0.0091 0.0126 0.0185
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.0344 0.0445
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0068 0.0082 0.0106
Trypanosoma cruzi histone deacetylase, putative 0.0377 0.0686 0.1005
Trypanosoma brucei zeta tubulin 0.0837 0.1586 0.2326
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0155 0.0253 0.0371
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Echinococcus multilocularis hypothetical protein 0.2545 0.4927 0.4927
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0155 0.0253 0.0371
Echinococcus multilocularis histone deacetylase 0.0377 0.0686 0.0686
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0075 0.0075
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0338 0.0611 0.0896
Schistosoma mansoni chromobox protein 0.0082 0.011 0.0142
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0017 0.0025
Brugia malayi CXXC zinc finger family protein 0.0034 0.0015 0.0023
Loa Loa (eye worm) tubulin alpha 2 0.1708 0.329 0.4826
Brugia malayi 'Paired box' domain containing protein 0.003 0.0008 0.0011
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0075 0.0097
Echinococcus multilocularis lysine specific demethylase 5A 0.0123 0.019 0.019
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0017 0.0022
Brugia malayi MH1 domain containing protein 0.0078 0.0101 0.0149
Trichomonas vaginalis tubulin beta chain, putative 0.2545 0.4927 0.7226
Mycobacterium leprae Probable lipase LipE 0.0043 0.0032 0.0188
Leishmania major histone deacetylase, putative 0.0377 0.0686 0.1005
Loa Loa (eye worm) paired box protein 0.003 0.0008 0.0011
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0142 0.0226 0.1263
Schistosoma mansoni hypothetical protein 0.0051 0.0048 0.0063
Brugia malayi Probable DNA topoisomerase II 0.0063 0.0072 0.0105
Schistosoma mansoni tubulin subunit beta 0.3512 0.6818 0.8818
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0013 0.0017
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0837 0.1586 0.2326
Loa Loa (eye worm) beta-lactamase 0.0043 0.0032 0.0047
Brugia malayi bHLH-PAS transcription factor 0.0078 0.0101 0.0148
Leishmania major trypanothione reductase 0.0056 0.0058 0.0085
Echinococcus granulosus tubulin beta 1 chain 0.3512 0.6818 0.8818
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0032 0.0018
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0033 0.0049
Loa Loa (eye worm) thioredoxin reductase 0.0056 0.0058 0.0085
Brugia malayi histone deacetylase 3 (HD3) 0.0775 0.1466 0.2149
Schistosoma mansoni histone deacetylase hda2 0.0258 0.0453 0.0586
Echinococcus granulosus tubulin alpha chain 0.2545 0.4927 0.6371
Trichomonas vaginalis tubulin alpha chain, putative 0.109 0.2082 0.3053
Schistosoma mansoni lamin 0.0062 0.007 0.0091
Brugia malayi Cytochrome P450 family protein 0.0043 0.0033 0.0049
Mycobacterium ulcerans thymidylate synthase 0.0127 0.0197 0.1078
Schistosoma mansoni hypothetical protein 0.0051 0.0048 0.0063
Trypanosoma brucei histone deacetylase 3 0.0377 0.0686 0.1005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0155 0.0253 0.0371
Brugia malayi Tubulin beta chain 0.0837 0.1586 0.2326
Trypanosoma cruzi zeta tubulin, putative 0.0837 0.1586 0.2326
Loa Loa (eye worm) tubulin beta-4 chain 0.3512 0.6818 1
Schistosoma mansoni histone deacetylase 0.0775 0.1466 0.1895
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0002 0.0004
Brugia malayi Probable isocitrate dehydrogenase 0.0041 0.0029 0.0043
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0179 0.0298 0.0438
Trichomonas vaginalis esterase, putative 0.0043 0.0032 0.0047
Loa Loa (eye worm) CYP4Cod1 0.0043 0.0033 0.0049
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.012 0.0176
Brugia malayi chromobox protein homolog 3 0.0046 0.0039 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0304 0.0544 0.0703
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0029 0.0006 0.0008
Plasmodium vivax thioredoxin reductase, putative 0.0056 0.0058 0.0085
Onchocerca volvulus 0.0127 0.0197 0.0657
Brugia malayi nuclear receptor RXR 0.0068 0.0082 0.012
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0128 0.02 0.0294
Echinococcus granulosus nuclear receptor nhr 48 0.0068 0.0082 0.0106
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0032 0.0047
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.002 0.002
Echinococcus granulosus Tubulin beta 2C chain 0.3512 0.6818 0.8818
Leishmania major zeta tubulin, putative 0.0837 0.1586 0.2326
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0047
Plasmodium vivax tubulin epsilon chain, putative 0.1927 0.3718 0.5454
Mycobacterium tuberculosis Cell division protein FtsZ 0.0837 0.1586 1
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.0033 0.0049
Schistosoma mansoni cpg binding protein 0.0036 0.0019 0.0025
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0013 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.0015 0.0023
Brugia malayi nuclear receptor NHR-88 0.0068 0.0082 0.012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0155 0.0253 0.0371
Loa Loa (eye worm) 6-phosphofructokinase 0.0128 0.02 0.0294
Echinococcus granulosus paired box protein pax 6 0.003 0.0008 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0029 0.0006 0.0006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.002 0.0029
Schistosoma mansoni tubulin subunit beta 0.3512 0.6818 0.8818
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0029 0.0006 0.0008
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0043 0.0034 0.0027
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0043 0.0034 0.0049
Brugia malayi MH2 domain containing protein 0.0141 0.0224 0.0329
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0075 0.011
Chlamydia trachomatis dihydrofolate reductase 0.0052 0.005 0.3588
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0143 0.0228 0.0334
Trypanosoma brucei alpha tubulin 0.2545 0.4927 0.7226
Toxoplasma gondii alpha-tubulin I, putative 0.2545 0.4927 0.7226
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0155 0.0253 0.0371
Echinococcus granulosus zinc finger transcription factor gli2 0.0303 0.0541 0.07
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0032 0.0047
Onchocerca volvulus 0.003 0.0008 0.0025
Trypanosoma brucei alpha tubulin, putative 0.109 0.2082 0.3053
Loa Loa (eye worm) phosphofructokinase 0.0128 0.02 0.0294
Echinococcus granulosus histone deacetylase 1 0.0775 0.1466 0.1895
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0045 0.0038 0.0126
Echinococcus multilocularis tubulin alpha 3 chain 0.2545 0.4927 0.4927
Schistosoma mansoni tubulin subunit gamma 0.1927 0.3718 0.4809
Echinococcus multilocularis Tubulin alpha 1 chain 0.2545 0.4927 0.4927
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.2545 0.4927 0.7226
Mycobacterium ulcerans lipase LipD 0.0043 0.0032 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.0344 0.0445
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.002
Echinococcus multilocularis Tubulin beta 2C chain 0.3512 0.6818 0.6818
Schistosoma mansoni smad1 5 8 and 0.0141 0.0224 0.029
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0075 0.011
Mycobacterium tuberculosis Probable reductase 0.0127 0.0198 0.1084
Plasmodium falciparum histone acetyltransferase GCN5 0.0129 0.0201 0.0295
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0032 0.0042
Leishmania major protein kinase, putative 0.0027 0.0002 0.0004
Toxoplasma gondii isocitrate dehydrogenase 0.0338 0.0611 0.0896
Echinococcus granulosus alpha tubulin 0.2545 0.4927 0.6371
Mycobacterium ulcerans endonuclease IV 0.0091 0.0126 0.0621
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0043 0.0034 0.0044
Echinococcus granulosus beta tubulin 0.3512 0.6818 0.8818
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Trypanosoma brucei tubulin gamma chain 0.1927 0.3718 0.5454
Onchocerca volvulus 0.0027 0.0002 0.0008
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0141 0.0224 0.029
Echinococcus granulosus tubulin epsilon chain 0.1927 0.3718 0.4809
Brugia malayi jmjC domain containing protein 0.0123 0.019 0.0279
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0013 0.0017
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.0228 0.0334
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0068 0.0082 0.012
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0029 0.0006 0.0008
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.006 0.0067 0.0098
Brugia malayi latrophilin 2 splice variant baaae 0.011 0.0164 0.024
Loa Loa (eye worm) jmjC domain-containing protein 0.0125 0.0194 0.0285
Trichomonas vaginalis chromobox protein, putative 0.0082 0.011 0.0161
Brugia malayi nuclear hormone receptor family member nhr-6 0.0068 0.0082 0.012
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0029 0.0006 0.0007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0155 0.0253 0.0327
Brugia malayi p25-alpha family protein 0.0432 0.0794 0.1165
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0009 0.0014
Trichomonas vaginalis tubulin epsilon chain, putative 0.2545 0.4927 0.7226
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0155 0.0253 0.0253
Plasmodium falciparum ataxin-2 like protein, putative 0.0298 0.0532 0.078
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0041 0.0029 0.0043
Brugia malayi jmjC domain containing protein 0.0033 0.0013 0.002
Brugia malayi hypothetical protein 0.0087 0.012 0.0176
Echinococcus granulosus FTZ F1 alpha 0.0155 0.0253 0.0327
Echinococcus multilocularis histone deacetylase 1 0.0775 0.1466 0.1466
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0013 0.0013
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0184 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0637 0.1195 0.1753
Echinococcus multilocularis mothers against decapentaplegic 5 0.0141 0.0224 0.0224
Echinococcus granulosus Tubulin beta 2C chain 0.3512 0.6818 0.8818
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.109 0.2082 0.3053
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0048 0.0071
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0155 0.0253 0.0842
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0143 0.0228 0.0334
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.02 0.0294
Schistosoma mansoni tubulin subunit beta 0.0837 0.1586 0.2051
Schistosoma mansoni smad 0.0141 0.0224 0.029
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0155 0.0253 0.0327
Loa Loa (eye worm) tubulin gamma chain 0.1927 0.3718 0.5454
Brugia malayi ecdysteroid receptor 0.0155 0.0253 0.0371
Schistosoma mansoni paired box protein pax-1-related 0.003 0.0008 0.001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0019 0.0019
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0041 0.0029 0.0043
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0009 0.0014
Brugia malayi nuclear receptor NHR-88 0.0155 0.0253 0.0371
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.002 0.0029
Echinococcus multilocularis ecdysone induced protein 78C 0.0155 0.0253 0.0253
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0072 0.0106
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0032 0.0042
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0041 0.0029 0.0029
Plasmodium falciparum thioredoxin reductase 0.0056 0.0058 0.0085
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0338 0.0611 0.0611
Leishmania major mitochondrial DNA topoisomerase II 0.0049 0.0045 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0155 0.0253 0.0327
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0017 0.0025
Loa Loa (eye worm) beta-tubulin 0.3512 0.6818 1
Echinococcus granulosus mothers against decapentaplegic 6 0.0063 0.0072 0.0093
Giardia lamblia Epsilon tubulin 0.0837 0.1586 0.2319
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0134 0.021 0.021
Echinococcus granulosus dihydrofolate reductase 0.0052 0.005 0.0065
Leishmania major gamma-tubulin 0.1927 0.3718 0.5454
Brugia malayi glutathione reductase 0.0056 0.0058 0.0085
Trichomonas vaginalis tubulin gamma chain, putative 0.3512 0.6818 1
Brugia malayi steroid hormone receptor 0.0155 0.0253 0.0371
Loa Loa (eye worm) tubulin beta chain 0.3512 0.6818 1
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0056 0.0059 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0155 0.0253 0.0371
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0017 0.0766
Trichomonas vaginalis tubulin epsilon chain, putative 0.0837 0.1586 0.2326
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.0344 0.0344
Echinococcus multilocularis isocitrate dehydrogenase 0.0338 0.0611 0.0611
Entamoeba histolytica acetyltransferase, GNAT family 0.0129 0.0201 0.0295
Leishmania major beta tubulin 0.3512 0.6818 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0141 0.0224 0.0224
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0032 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.0043 0.0034 0.0049
Treponema pallidum exodeoxyribonuclease (exoA) 0.0043 0.0034 0.0107
Brugia malayi ecdysone receptor 0.0068 0.0082 0.012
Entamoeba histolytica tubulin alpha-1 chain 0.2545 0.4927 0.7226
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0067 0.0098
Schistosoma mansoni alpha tubulin 0.2545 0.4927 0.6371
Echinococcus granulosus neuropeptide receptor A26 0.0551 0.1026 0.1327
Schistosoma mansoni smad 0.0063 0.0072 0.0093
Schistosoma mansoni Smad4 0.0063 0.0072 0.0093
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0127 0.0197 0.0255
Brugia malayi jmjC domain containing protein 0.0033 0.0013 0.002
Schistosoma mansoni tubulin subunit alpha 0.2545 0.4927 0.6371
Brugia malayi MH1 domain containing protein 0.0141 0.0224 0.0329
Schistosoma mansoni tubulin subunit beta 0.3512 0.6818 0.8818
Trypanosoma brucei beta tubulin 0.3512 0.6818 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Brugia malayi hypoxia-induced factor 1 0.0325 0.0584 0.0857
Loa Loa (eye worm) heterochromatin protein 1 0.0082 0.011 0.0161
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0247 0.0431 0.0632
Plasmodium vivax tubulin alpha chain, putative 0.2545 0.4927 0.7226
Loa Loa (eye worm) MH1 domain-containing protein 0.0141 0.0224 0.0329
Echinococcus granulosus tumor protein p63 0.0778 0.147 0.1901
Loa Loa (eye worm) hypothetical protein 0.0145 0.0232 0.0341
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0336 0.0606 0.0889
Brugia malayi hypothetical protein 0.0192 0.0325 0.0477
Brugia malayi hypothetical protein 0.0078 0.0101 0.0149
Schistosoma mansoni hypothetical protein 0.0051 0.0048 0.0063
Echinococcus multilocularis mothers against decapentaplegic 2 0.0063 0.0072 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0155 0.0253 0.0327
Echinococcus granulosus tubulin alpha 0.1927 0.3718 0.4809
Trypanosoma brucei histone deacetylase 2 0.0258 0.0453 0.0665
Onchocerca volvulus 0.0062 0.007 0.0235
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0697 0.1312 0.1697
Schistosoma mansoni jumonji/arid domain-containing protein 0.0125 0.0194 0.0251
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0017 0.0025
Onchocerca volvulus Protein ultraspiracle homolog 0.0155 0.0253 0.0842
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0068 0.0082 0.012
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0091 0.0126 0.0621
Schistosoma mansoni CREB-binding protein 2 0.0131 0.0206 0.0266
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0045 0.0038 0.0126
Brugia malayi mothers against decapentaplegic homolog 3 0.0063 0.0072 0.0106
Echinococcus multilocularis FTZ F1 alpha 0.0155 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0352 0.0638 0.0935
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0161 0.0263 0.0386
Loa Loa (eye worm) alpha-tubulin 0.2545 0.4927 0.7226
Loa Loa (eye worm) hypothetical protein 0.0298 0.0532 0.078
Schistosoma mansoni nuclear receptor nhr-48 0.0068 0.0082 0.0106
Mycobacterium ulcerans hypothetical protein 0.0043 0.0032 0.0018
Entamoeba histolytica tubulin family protein 0.3512 0.6818 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0002 0.0004
Echinococcus granulosus histone deacetylase 7 0.0377 0.0686 0.0887
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0155 0.0253 0.0371
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0202 0.0344 0.0505
Plasmodium vivax histone deacetylase 2, putative 0.0377 0.0686 0.1005
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0002 0.0004
Schistosoma mansoni cellular tumor antigen P53 0.0114 0.0172 0.0222
Schistosoma mansoni smad1 5 8 and 0.0141 0.0224 0.029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0047
Plasmodium falciparum flap endonuclease 1 0.0031 0.0009 0.0014
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0075 0.011
Trichomonas vaginalis tubulin beta chain, putative 0.109 0.2082 0.3053
Schistosoma mansoni retinoic acid receptor RXR 0.0272 0.048 0.0621
Echinococcus multilocularis Tubulin alpha 1 chain 0.2545 0.4927 0.4927
Trypanosoma brucei trypanothione reductase 0.0056 0.0058 0.0085
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0049 0.0045 0.0067
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.002 0.002
Echinococcus granulosus tubulin subunit beta 0.3512 0.6818 0.8818
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0155 0.0253 0.0371
Echinococcus granulosus Tubulin alpha 1 chain 0.2545 0.4927 0.6371
Trichomonas vaginalis chromobox protein, putative 0.0082 0.011 0.0161
Loa Loa (eye worm) hypothetical protein 0.0637 0.1195 0.1753
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Onchocerca volvulus Retinal homeobox protein Rx homolog 0.003 0.0008 0.0025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.048 0.0887 0.0887
Echinococcus multilocularis tubulin beta 1 chain 0.3512 0.6818 0.6818
Echinococcus granulosus neuropeptide s receptor 0.0551 0.1026 0.1327
Leishmania major hypothetical protein, conserved 0.0298 0.0532 0.078
Onchocerca volvulus 0.028 0.0498 0.1658
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0032 0.0047
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0155 0.0253 0.0253
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0041 0.0029 0.0171
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0041 0.0029 0.0043
Echinococcus multilocularis tumor protein p63 0.0778 0.147 0.147
Trypanosoma cruzi PAB1-binding protein , putative 0.0298 0.0532 0.078
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Echinococcus granulosus tubulin beta 4A class IVa 0.3512 0.6818 0.8818
Echinococcus granulosus Tubulin alpha 1 chain 0.2545 0.4927 0.6371
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.002 0.0029
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Echinococcus granulosus Tubulin beta 2C chain 0.3512 0.6818 0.8818
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0047
Echinococcus multilocularis tubulin alpha chain 0.2545 0.4927 0.4927
Mycobacterium ulcerans beta-lactamase 0.0043 0.0032 0.0018
Brugia malayi histone deacetylase 11 0.0258 0.0453 0.0665
Brugia malayi Tubulin alpha-2 chain 0.2545 0.4927 0.7226
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0127 0.0198 0.1084
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0155 0.0253 0.0371
Loa Loa (eye worm) hypothetical protein 0.0078 0.0101 0.0149
Brugia malayi MH2 domain containing protein 0.0141 0.0224 0.0329
Trichomonas vaginalis tubulin beta chain, putative 0.2545 0.4927 0.7226
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Loa Loa (eye worm) MH2 domain-containing protein 0.0141 0.0224 0.0329
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0155 0.0253 0.0371
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0046
Schistosoma mansoni jumonji/arid domain-containing protein 0.0125 0.0194 0.0251
Toxoplasma gondii endonuclease IV APN 0.0091 0.0126 0.0185
Loa Loa (eye worm) nuclear receptor NHR-67 0.0068 0.0082 0.012
Trichomonas vaginalis set domain proteins, putative 0.028 0.0498 0.073
Leishmania major beta tubulin 0.3512 0.6818 1
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0032 0.0018
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0009 0.0014
Trypanosoma brucei epsilon tubulin 0.1927 0.3718 0.5454
Brugia malayi hypothetical protein 0.0778 0.147 0.2156
Loa Loa (eye worm) nuclear factor I 0.0078 0.0101 0.0149
Schistosoma mansoni tubulin subunit alpha 0.2545 0.4927 0.6371
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0017 0.0025
Echinococcus multilocularis histone deacetylase 8 0.0258 0.0453 0.0453
Loa Loa (eye worm) histone deacetylase 7A 0.0377 0.0686 0.1005
Brugia malayi bZIP transcription factor family protein 0.0099 0.0143 0.021
Trypanosoma brucei tubulin delta chain 0.0837 0.1586 0.2326
Brugia malayi nuclear receptor NHR-67 0.0068 0.0082 0.012
Schistosoma mansoni intermediate filament proteins 0.0062 0.007 0.0091
Leishmania major beta tubulin 0.3512 0.6818 1
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Trichomonas vaginalis tubulin epsilon chain, putative 0.3512 0.6818 1
Echinococcus multilocularis neuropeptide s receptor 0.0551 0.1026 0.1026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0032 0.0042
Schistosoma mansoni tubulin subunit delta 0.0837 0.1586 0.2051
Entamoeba histolytica phosphofructokinase, putative 0.0128 0.02 0.0294
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0338 0.0611 0.0896
Brugia malayi paired box pox-meso protein 0.003 0.0008 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0127 0.0198 0.1084
Brugia malayi tubulin alpha chain - mouse 0.2545 0.4927 0.7226
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0068 0.0082 0.0273
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0017 0.0025
Leishmania major histone deacetylase, putative 0.0377 0.0686 0.1005
Brugia malayi Heterochromatin protein 1 0.0082 0.011 0.0161
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0002 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0155 0.0253 0.0327
Echinococcus multilocularis zinc finger transcription factor gli2 0.0303 0.0541 0.0541
Echinococcus multilocularis tubulin alpha 1C chain 0.2545 0.4927 0.4927
Trichomonas vaginalis histone deacetylase, putative 0.0775 0.1466 0.2149
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0338 0.0611 0.0896
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Loa Loa (eye worm) tubulin alpha chain 0.2545 0.4927 0.7226
Brugia malayi Flap endonuclease-1 0.0031 0.0009 0.0014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0006 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0155 0.0253 0.0371
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0002 0.0004
Mycobacterium ulcerans putative regulatory protein 0.0078 0.0101 0.046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0004
Mycobacterium ulcerans 6-phosphofructokinase 0.0128 0.02 0.1097
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Trichomonas vaginalis tubulin beta chain, putative 0.2545 0.4927 0.7226
Loa Loa (eye worm) hypothetical protein 0.0087 0.012 0.0176
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0032 0.0047
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0002 0.0004
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0019 0.0019
Loa Loa (eye worm) tubulin alpha 2 0.0618 0.1157 0.1698
Echinococcus granulosus Tubulin beta 2C chain 0.3512 0.6818 0.8818
Echinococcus granulosus ecdysone induced protein 78C 0.0155 0.0253 0.0327
Plasmodium falciparum tubulin gamma chain 0.1927 0.3718 0.5454
Trichomonas vaginalis tubulin beta chain, putative 0.2545 0.4927 0.7226
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0029 0.0006 0.0008
Brugia malayi Pre-SET motif family protein 0.0036 0.0019 0.0029
Loa Loa (eye worm) tubulin beta chain 0.0837 0.1586 0.2326
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0272 0.048 0.2897
Giardia lamblia Beta tubulin 0.3512 0.6818 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0155 0.0253 0.0371
Echinococcus granulosus peroxisome assembly protein 26 0.2545 0.4927 0.6371
Brugia malayi Dihydrofolate reductase 0.0052 0.005 0.0074
Loa Loa (eye worm) hypothetical protein 0.0061 0.0068 0.01
Toxoplasma gondii histone lysine methyltransferase SET1 0.0079 0.0104 0.0153
Onchocerca volvulus 0.0062 0.007 0.0235
Schistosoma mansoni hypothetical protein 0.0051 0.0048 0.0063
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0029 0.0006 0.0008
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0006 0.0008
Echinococcus multilocularis smad 0.0141 0.0224 0.0224
Schistosoma mansoni 6-phosphofructokinase 0.0128 0.02 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0013 0.0019
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0009 0.0014
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0068 0.0082 0.0082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.0344 0.0445
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0052 0.005 0.0134
Echinococcus multilocularis thioredoxin glutathione reductase 0.0056 0.0058 0.0058
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0127 0.0198 0.1084
Echinococcus multilocularis beta tubulin 0.3512 0.6818 0.6818
Brugia malayi 6-phosphofructokinase 0.0128 0.02 0.0294
Trichomonas vaginalis tubulin, putative 0.0837 0.1586 0.2326
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0123 0.019 0.019
Leishmania major hypothetical protein, conserved 0.0033 0.0013 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.02 0.0294
Onchocerca volvulus 0.0036 0.002 0.0066
Trypanosoma cruzi beta tubulin, putative 0.3512 0.6818 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0006 0.0008
Trichomonas vaginalis adenylate cyclase, putative 0.0027 0.0002 0.0004
Schistosoma mansoni paired box protein pax-6 0.003 0.0008 0.001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0056 0.0058 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0002 0.0004
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0128 0.02 0.1097
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0013 0.002
Schistosoma mansoni isocitrate dehydrogenase 0.0041 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Onchocerca volvulus TPPP family protein homolog 0.0432 0.0794 0.2646
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0155 0.0253 0.0327
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0068 0.0082 0.0082
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0091 0.0126 0.0185
Leishmania major histone deacetylase, putative 0.0775 0.1466 0.2149
Loa Loa (eye worm) hypothetical protein 0.0087 0.012 0.0176
Loa Loa (eye worm) BEN-1 protein 0.3512 0.6818 1
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0029 0.0006 0.0007
Brugia malayi hypothetical protein 0.0068 0.0082 0.012
Echinococcus multilocularis tubulin alpha 0.1927 0.3718 0.3718
Loa Loa (eye worm) hypothetical protein 0.1455 0.2794 0.4098
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0155 0.0253 0.0327
Loa Loa (eye worm) tubulin beta-1 chain 0.3512 0.6818 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0155 0.0253 0.0253
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0046 0.0154
Loa Loa (eye worm) tubulin alpha-3 chain 0.1455 0.2794 0.4098
Loa Loa (eye worm) hypothetical protein 0.0042 0.0031 0.0046
Loa Loa (eye worm) MH1 domain-containing protein 0.0063 0.0072 0.0106
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0041 0.0029 0.0038
Echinococcus granulosus geminin 0.398 0.7733 1
Echinococcus granulosus tubulin gamma 1 chain 0.1927 0.3718 0.4809
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0002 0.0004
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0029 0.0006 0.0008
Onchocerca volvulus 0.0155 0.0253 0.0842
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0005
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0032 0.0047
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Echinococcus multilocularis paired box protein pax 6 0.003 0.0008 0.0008
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0027 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0155 0.0253 0.0371
Brugia malayi Histone deacetylase 1 0.0775 0.1466 0.2149
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0338 0.0611 0.0611
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0068 0.0082 0.0106
Plasmodium falciparum alpha tubulin 1 0.2545 0.4927 0.7226
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.002
Plasmodium vivax SET domain protein, putative 0.0036 0.0019 0.0029
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0052 0.005 0.0134
Schistosoma mansoni jun-related protein 0.0081 0.0107 0.0138
Brugia malayi MH2 domain containing protein 0.2066 0.399 0.5851
Echinococcus multilocularis paired box protein pax 1 0.003 0.0008 0.0008
Toxoplasma gondii beta-1 tubulin, putative 0.3512 0.6818 1
Brugia malayi nuclear hormone receptor 0.0155 0.0253 0.0371
Echinococcus multilocularis tubulin epsilon chain 0.1927 0.3718 0.3718
Schistosoma mansoni tubulin subunit epsilon 0.1927 0.3718 0.4809
Brugia malayi jmjC domain containing protein 0.0033 0.0013 0.002
Toxoplasma gondii histone deacetylase HDAC2 0.0775 0.1466 0.2149
Schistosoma mansoni paired box protein pax-6 0.003 0.0008 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0155 0.0253 0.0371
Echinococcus multilocularis Tubulin beta 2C chain 0.3512 0.6818 0.6818
Schistosoma mansoni DNA topoisomerase II 0.0063 0.0072 0.0093
Loa Loa (eye worm) cytochrome P450 family protein 0.0091 0.0126 0.0185
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0058 0.0085
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.002 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.002 0.0029
Loa Loa (eye worm) MH2 domain-containing protein 0.0063 0.0072 0.0106
Brugia malayi tubulin alpha-2 chain 0.2545 0.4927 0.7226
Echinococcus granulosus single minded 2 0.0078 0.0101 0.0131
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0128 0.02 0.1249
Brugia malayi jmjC domain containing protein 0.0033 0.0013 0.002
Schistosoma mansoni hypothetical protein 0.0081 0.0107 0.0138
Echinococcus multilocularis paired box protein pax 6 0.003 0.0008 0.0008
Mycobacterium ulcerans cell division protein FtsZ 0.0837 0.1586 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.002 0.0026
Loa Loa (eye worm) histone deacetylase 3 0.0775 0.1466 0.2149
Echinococcus granulosus histone deacetylase 8 0.0258 0.0453 0.0586
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0155 0.0253 0.0371
Trypanosoma cruzi zeta tubulin, putative 0.0837 0.1586 0.2326
Trypanosoma brucei epsilon tubulin 0.1927 0.3718 0.5454
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.002 0.0026
Brugia malayi thymidylate synthase 0.0127 0.0197 0.0289
Onchocerca volvulus 0.0043 0.0032 0.0107
Trichomonas vaginalis histone deacetylase, putative 0.0775 0.1466 0.2149
Trypanosoma brucei alpha tubulin 0.2545 0.4927 0.7226
Onchocerca volvulus 0.0078 0.0101 0.0338
Brugia malayi Cytochrome P450 family protein 0.0091 0.0126 0.0185
Trypanosoma cruzi histone deacetylase 1, putative 0.0775 0.1466 0.2149
Toxoplasma gondii histone deacetylase HDAC5 0.0258 0.0453 0.0665
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0009 0.0005
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0338 0.0609 0.0894
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0041 0.0029 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0032 0.0018
Brugia malayi hypothetical protein 0.0352 0.0638 0.0935
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0043 0.0034 0.0049
Plasmodium falciparum glutathione reductase 0.0056 0.0058 0.0085
Echinococcus multilocularis tubulin alpha chain 0.2545 0.4927 0.4927
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1455 0.2794 0.4098
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0775 0.1466 0.2149
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0033 0.0049
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0045 0.0038 0.0126
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0149 0.024 0.024
Onchocerca volvulus 0.0778 0.147 0.4897
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0155 0.0253 0.0327
Plasmodium vivax tubulin alpha chain, putative 0.2545 0.4927 0.7226
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0338 0.0611 0.0896
Echinococcus multilocularis cpg binding protein 0.0036 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0837 0.1586 0.2326
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0043 0.0034 0.0049
Brugia malayi isocitrate dehydrogenase 0.0338 0.0611 0.0896
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.02 0.0294
Brugia malayi Intermediate filament tail domain containing protein 0.0062 0.007 0.0103
Leishmania major beta tubulin 0.3512 0.6818 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0032 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0155 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0008
Giardia lamblia Alpha-tubulin 0.2545 0.4927 0.7223
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0032 0.0018
Echinococcus multilocularis paired box protein pax 6 0.003 0.0008 0.0008
Entamoeba histolytica phosphofructokinase, putative 0.0128 0.02 0.0294
Loa Loa (eye worm) hypothetical protein 0.0036 0.002 0.0029
Leishmania major alpha tubulin 0.2545 0.4927 0.7226
Plasmodium falciparum tubulin delta chain, putative 0.0837 0.1586 0.2326
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0063 0.0072 0.0072
Trichomonas vaginalis tubulin beta chain, putative 0.2545 0.4927 0.7226
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0155 0.0253 0.0327
Brugia malayi Histone deacetylase family protein 0.0377 0.0686 0.1005
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0006 0.0008
Trichomonas vaginalis histone deacetylase, putative 0.0775 0.1466 0.2149
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0006 0.0008
Trichomonas vaginalis tubulin alpha chain, putative 0.3512 0.6818 1
Brugia malayi paired box protein 0.003 0.0008 0.0011
Echinococcus multilocularis 6 phosphofructokinase 0.0128 0.02 0.02
Echinococcus multilocularis tubulin gamma 1 chain 0.1927 0.3718 0.3718
Echinococcus granulosus muscleblind protein 0.0637 0.1195 0.1546
Loa Loa (eye worm) hypothetical protein 0.0087 0.012 0.0176
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0027 0.0002 0.0004
Loa Loa (eye worm) p25-alpha family protein 0.0432 0.0794 0.1165
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0075 0.011
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0338 0.0611 0.0896
Echinococcus multilocularis histone deacetylase 6 0.0403 0.0736 0.0736
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.002 0.0029
Echinococcus multilocularis muscleblind protein 0.0637 0.1195 0.1195
Trypanosoma brucei beta tubulin 0.3512 0.6818 1
Schistosoma mansoni cpg binding protein 0.0036 0.0019 0.0025
Plasmodium vivax histone deacetylase, putative 0.0377 0.0686 0.1005
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0013 0.002
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0034 0.0049
Brugia malayi acetyltransferase, GNAT family protein 0.048 0.0887 0.1301
Leishmania major beta tubulin 0.3512 0.6818 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0048 0.0071

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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