Detailed information for compound 92025

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 515.454 | Formula: C20H30N5O9P
  • H donors: 7 H acceptors: 8 LogP: -2.25 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 3
  • SMILES: CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CC(=O)N)C(C)C)Cc1ccc(cc1)OP(=O)(O)O
  • InChi: 1S/C20H30N5O9P/c1-10(2)17(20(30)24-14(18(22)28)9-16(21)27)25-19(29)15(23-11(3)26)8-12-4-6-13(7-5-12)34-35(31,32)33/h4-7,10,14-15,17H,8-9H2,1-3H3,(H2,21,27)(H2,22,28)(H,23,26)(H,24,30)(H,25,29)(H2,31,32,33)/t14-,15-,17-/m0/s1
  • InChiKey: GSJUDVVVSUJCMF-ZOBUZTSGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens growth factor receptor-bound protein 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni growth factor receptor-bound protein Get druggable targets OG5_131257 All targets in OG5_131257
Brugia malayi Sex muscle abnormal protein 5 Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma japonicum ko:K04364 growth factor receptor-binding protein 2, putative Get druggable targets OG5_131257 All targets in OG5_131257
Echinococcus multilocularis growth factor receptor bound protein 2 Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma japonicum Growth factor receptor-bound protein 2, putative Get druggable targets OG5_131257 All targets in OG5_131257
Loa Loa (eye worm) sex muscle abnormal protein 5 Get druggable targets OG5_131257 All targets in OG5_131257
Echinococcus granulosus growth factor receptor bound protein 2 Get druggable targets OG5_131257 All targets in OG5_131257
Schistosoma mansoni growth factor receptor-bound protein Get druggable targets OG5_131257 All targets in OG5_131257
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major hypothetical protein, conserved growth factor receptor-bound protein 2 217 aa 200 aa 23.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei glycerol uptake protein, putative 0.0067 0.0446 0.0838
Echinococcus multilocularis tyrosine protein kinase Abl 0.0541 0.4106 0.4106
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0076 0.0076
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0008 0.0008
Plasmodium falciparum heat shock protein 90 0.0039 0.0225 0.505
Trichomonas vaginalis penicillin-binding protein, putative 0.001 0 0.0003
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0016 0.0366
Schistosoma mansoni opsin-like receptor 0.002 0.0076 0.0078
Brugia malayi Melatonin receptor type 1A 0.002 0.0076 0.0126
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Trypanosoma cruzi glycerol uptake protein, putative 0.0067 0.0446 0.0838
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0261 0.0266
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.002 0.0076 0.0078
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.0088 0.0416
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0225 0.505
Onchocerca volvulus Poor gastrulation protein homolog 0.0084 0.0573 0.3141
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0025 0.0117 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Entamoeba histolytica BAR/SH3 domain containing protein 0.0024 0.0111 0.2489
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0253 0.0476
Brugia malayi SET domain containing protein 0.0014 0.0031 0.0051
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0039 0.0225 0.1946
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0016 0.0016
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0015 0.0126
Loa Loa (eye worm) hypothetical protein 0.0039 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0025 0.0116 0.0116
Toxoplasma gondii DNA topoisomerase 2, putative 0.0039 0.0225 0.1067
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0039 0.0225 0.1231
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0039 0.0225 0.0423
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0021 0.0088 0.0164
Trypanosoma cruzi glycerol uptake protein, putative 0.0067 0.0446 0.0838
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0039 0.0225 0.1946
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0111 0.0208
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0025 0.0117 0.0117
Plasmodium vivax importin-beta 2, putative 0.0031 0.0167 0.3753
Loa Loa (eye worm) hypothetical protein 0.0184 0.1343 0.1343
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0048 0.0261
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0021 0.0088 0.0164
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0039 0.0225 0.0423
Brugia malayi RhoGAP domain containing protein 0.0025 0.0116 0.0192
Brugia malayi cytokine inducible SH2-containing protein 5 0.0025 0.0116 0.0192
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0366
Plasmodium falciparum glutathione reductase 0.0015 0.0039 0.0866
Echinococcus granulosus c src tyrosine kinase 0.0054 0.0342 0.0342
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0039 0.0225 0.0423
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0008 0.0008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0342 0.0342
Echinococcus multilocularis tyrosine protein kinase Blk 0.003 0.0156 0.0156
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0274 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0024 0.0111 0.0111
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0039 0.0225 0.1946
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0039 0.0225 0.1946
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0039 0.0225 0.505
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0076 0.0078
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.044 0.0732
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Schistosoma mansoni hypothetical protein 0.0028 0.0141 0.0144
Entamoeba histolytica DNA topoisomerase II, putative 0.0039 0.0225 0.505
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0008 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0049 0.0301 0.0301
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0039 0.0225 0.0423
Brugia malayi CHD4 protein 0.0014 0.0031 0.0051
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0076 0.0076
Brugia malayi Src substrate cortactin 0.0024 0.0111 0.0184
Echinococcus multilocularis NCK adaptor protein 0.0049 0.0301 0.0301
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0274 0.028
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0024 0.0111 0.0111
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Onchocerca volvulus 0.002 0.0076 0.0415
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0016 0.0366
Brugia malayi hypothetical protein 0.0025 0.0116 0.0192
Brugia malayi latrophilin 2 splice variant baaae 0.0054 0.034 0.0566
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0025 0.0116 0.0116
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0076 0.0076
Echinococcus multilocularis tyrosine protein kinase Fyn 0.003 0.0156 0.0156
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0225 0.0423
Loa Loa (eye worm) hhat protein 0.0067 0.0446 0.0445
Onchocerca volvulus 0.0025 0.0116 0.0631
Brugia malayi N-terminal motif family protein 0.0108 0.0757 0.126
Toxoplasma gondii thioredoxin reductase 0.0015 0.0039 0.0183
Schistosoma mansoni biogenic amine receptor 0.002 0.0076 0.0078
Trichomonas vaginalis hypothetical protein 0.0012 0.0016 0.0089
Schistosoma mansoni neuropeptide receptor 0.002 0.0076 0.0078
Echinococcus multilocularis chromobox protein 2 0.0012 0.0016 0.0016
Brugia malayi Dopamine receptor protein 2 0.002 0.0076 0.0126
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0076 0.0076
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0076 0.0078
Schistosoma mansoni hypothetical protein 0.0024 0.0111 0.0113
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0076 0.0076
Brugia malayi Cytochrome P450 family protein 0.0035 0.0199 0.033
Trypanosoma brucei Heat shock protein 83, putative 0.0039 0.0225 0.0423
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Schistosoma mansoni formin binding protein and related proteins 0.0024 0.0111 0.0113
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0039 0.0225 0.1233
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0076 0.0078
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0068 0.0128
Schistosoma mansoni adenoreceptor 0.002 0.0076 0.0078
Entamoeba histolytica vacuolar protein sorting 26 0.0067 0.0446 1
Schistosoma mansoni tar DNA-binding protein 0.0067 0.044 0.0448
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0076 0.0076
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0025 0.0117 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0076 0.0076
Brugia malayi Guanylyl cyclase protein 23 0.0054 0.0341 0.0567
Loa Loa (eye worm) hypothetical protein 0.0637 0.4843 0.4842
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0342 0.0342
Schistosoma mansoni hypothetical protein 0.0084 0.0573 0.0585
Schistosoma mansoni DNA topoisomerase II 0.0039 0.0225 0.0229
Schistosoma mansoni hypothetical protein 0.0476 0.3605 0.3675
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0034 0.0184 0.8171
Onchocerca volvulus 0.0025 0.0116 0.0631
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0067 0.0446 0.0446
Echinococcus granulosus jun protein 0.0034 0.019 0.019
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0088 0.0165
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Schistosoma mansoni C-fyn 0.0024 0.0111 0.0113
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Entamoeba histolytica hypothetical protein 0.002 0.0077 0.173
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Trichomonas vaginalis DNA topoisomerase II, putative 0.0039 0.0225 0.1233
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0076 0.0126
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.021 0.4723
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Echinococcus granulosus glutamate receptor 2 0.0049 0.0301 0.0301
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0049 0.0301 0.03
Onchocerca volvulus 0.002 0.0076 0.0415
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0067 0.0446 0.0454
Echinococcus multilocularis chromobox protein 1 0.0072 0.0482 0.0482
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0067 0.0446 0.0445
Schistosoma mansoni dynamin-associated protein 0.0024 0.0111 0.0113
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0274 0.0274
Entamoeba histolytica hypothetical protein 0.0049 0.0301 0.6749
Trichomonas vaginalis esterase, putative 0.001 0 0.0003
Echinococcus multilocularis geminin 0.0114 0.0808 0.0808
Loa Loa (eye worm) hypothetical protein 0.0033 0.0183 0.0183
Echinococcus granulosus nostrin 0.0024 0.0111 0.0111
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0068 0.0587
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0068 0.0128
Loa Loa (eye worm) follicle stimulating hormone receptor 0.002 0.0076 0.0076
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Brugia malayi PHD-finger family protein 0.003 0.0158 0.0263
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0021 0.0088 0.1971
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0008 0.0008
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Schistosoma mansoni hypothetical protein 0.0025 0.0116 0.0118
Loa Loa (eye worm) hypothetical protein 0.0054 0.034 0.034
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0012 0.0017 0.0378
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0151 0.0154
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0222 0.0226
Echinococcus multilocularis receptor type guanylyl cyclase 0.0054 0.0341 0.0341
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0008 0.0008
Schistosoma mansoni tensin 0.0025 0.0116 0.0118
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0088 0.0146
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0008 0.0008
Schistosoma mansoni jun-related protein 0.0028 0.0141 0.0144
Toxoplasma gondii heat shock protein 90, putative 0.0039 0.0225 0.1067
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0244 0.181 0.3404
Echinococcus granulosus NCK adaptor protein 0.0049 0.0301 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Brugia malayi SH3 domain containing protein 0.0024 0.0111 0.0184
Echinococcus granulosus hypothetical protein 0.0025 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.002 0.0077 0.173
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Mycobacterium ulcerans DNA gyrase subunit B 0.0039 0.0225 0.1946
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0016 0.0077
Onchocerca volvulus 0.002 0.0076 0.0415
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0103 0.0103
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0698 0.5316 1
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0024 0.0111 0.0111
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.044 0.0439
Onchocerca volvulus 0.002 0.0076 0.0415
Echinococcus multilocularis fmrfamide receptor 0.002 0.0076 0.0076
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.021 0.1153
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0074 0.0076
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0017
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0225 0.1233
Schistosoma mansoni amine GPCR 0.002 0.0076 0.0078
Brugia malayi steroid hormone receptor 0.0011 0.0008 0.0013
Echinococcus multilocularis neuropeptide s receptor 0.002 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0054 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0532 0.0542
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0076 0.0076
Echinococcus multilocularis signal transduction protein lnk realted 0.0025 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0054 0.034 0.0347
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0076 0.0078
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0039 0.0225 0.1946
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Entamoeba histolytica hypothetical protein, conserved 0.0067 0.0446 1
Onchocerca volvulus 0.002 0.0076 0.0415
Brugia malayi Tyrosine-protein kinase abl-1 0.0541 0.4106 0.6837
Trypanosoma cruzi GUP1, putative 0.0067 0.0446 0.0838
Onchocerca volvulus 0.0024 0.0111 0.0605
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Toxoplasma gondii histone lysine demethylase JMJD6a 0.001 0 0.0002
Echinococcus granulosus metabotropic glutamate receptor 2 0.0433 0.3271 0.3271
Brugia malayi hypothetical protein 0.0027 0.0134 0.0222
Loa Loa (eye worm) latrophilin receptor protein 2 0.0025 0.0117 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0067 0.044 0.0448
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0039 0.0225 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0016 0.0077
Brugia malayi hypothetical protein 0.0049 0.0301 0.05
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0075 0.041
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Brugia malayi Probable DNA topoisomerase II 0.0039 0.0225 0.0374
Schistosoma mansoni biogenic amine receptor 0.002 0.0076 0.0078
Brugia malayi Sex muscle abnormal protein 5 0.0189 0.1383 0.2303
Giardia lamblia PHD finger protein 15 0.003 0.0158 0.7033
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0015 0.0028
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0049 0.0301 0.0301
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0482 0.2642
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0067 0.0446 0.0454
Trypanosoma brucei trypanothione reductase 0.0015 0.0039 0.0072
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0024 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0032 0.017 0.017
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.025 0.025
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0021 0.0088 0.0164
Schistosoma mansoni apoptosis stimulating of P53 0.0024 0.0111 0.0113
Loa Loa (eye worm) MBOAT family protein 0.0067 0.0446 0.0445
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0342 0.0342
Loa Loa (eye worm) MBOAT family protein 0.0067 0.0446 0.0445
Leishmania major importin beta-1 subunit, putative 0.0025 0.0121 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0261 0.1431
Echinococcus multilocularis intersectin 2 0.0024 0.0111 0.0111
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0076 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0225 0.0225
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0025 0.0116 0.0116
Loa Loa (eye worm) inositol-1 0.0037 0.021 0.021
Onchocerca volvulus 0.0024 0.0111 0.0605
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Echinococcus multilocularis jun protein 0.0034 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0088 0.0088
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0029 0.0149 0.0279
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0008 0.0008
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Onchocerca volvulus 0.0246 0.1825 1
Loa Loa (eye worm) hypothetical protein 0.0133 0.0949 0.0949
Schistosoma mansoni protein kinase 0.0054 0.0341 0.0348
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0076 0.0126
Schistosoma mansoni neuropeptide receptor 0.002 0.0076 0.0078
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0008 0.0008
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0698 0.5316 0.5316
Onchocerca volvulus 0.002 0.0076 0.0415
Onchocerca volvulus 0.0012 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0225 0.505
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0089
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0167 0.0793
Brugia malayi Thioredoxin reductase 0.0015 0.0039 0.0064
Brugia malayi nuclear receptor NHR-88 0.0011 0.0008 0.0013
Echinococcus multilocularis dnaJ subfamily B 0.0476 0.3605 0.3605
Entamoeba histolytica hypothetical protein 0.0029 0.0149 0.3334
Brugia malayi Protein cec-1. 0.0012 0.0016 0.0027
Entamoeba histolytica SH2 domain containing protein 0.0025 0.0116 0.2595
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0039 0.0225 0.1946
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0076 0.0076
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0341 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Echinococcus multilocularis microtubule associated protein 2 0.0714 0.5443 0.5443
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0021 0.0088 0.0164
Echinococcus granulosus tyrosine kinase 0.003 0.0156 0.0156
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0025 0.0116 0.0116
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0076 0.0078
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.1154 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0068 0.0068
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0067 0.0446 0.0446
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0024 0.0111 0.0111
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0008 0.0013
Loa Loa (eye worm) glutamate receptor 0.0517 0.392 0.3919
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0698 0.5316 0.5316
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0121 0.0665
Plasmodium falciparum DNA gyrase subunit B 0.0039 0.0225 0.505
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0008 0.0008
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0025 0.0116 0.0116
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0076 0.0076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0008 0.0008
Leishmania major mitochondrial DNA topoisomerase II 0.0039 0.0225 0.0423
Schistosoma mansoni tyrosine kinase 0.003 0.0156 0.0159
Leishmania major glycerol uptake protein, putative 0.0067 0.0446 0.0838
Brugia malayi glutathione reductase 0.0015 0.0039 0.0064
Onchocerca volvulus 0.0025 0.0116 0.0631
Echinococcus granulosus expressed protein 0.0024 0.0111 0.0111
Onchocerca volvulus 0.0054 0.0341 0.1867
Echinococcus multilocularis chromobox protein 1 0.0072 0.0482 0.0482
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0423 0.2007
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0108 0.0757 0.4148
Schistosoma mansoni chromobox protein 0.0072 0.0482 0.0492
Brugia malayi Variant SH3 domain containing protein 0.0024 0.0111 0.0184
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0169 0.0169
Entamoeba histolytica protein kinase, putative 0.0024 0.0111 0.2489
Loa Loa (eye worm) hypothetical protein 0.0067 0.0446 0.0445
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.012
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0067 0.0446 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0374
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.2258 0.4248
Echinococcus granulosus jumonji domain containing protein 0.0042 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.0301
Onchocerca volvulus 0.0011 0.0008 0.0041
Brugia malayi bZIP transcription factor family protein 0.0034 0.019 0.0317
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0076 0.0076
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0076 0.0078
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0039 0.0225 0.1233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0079 0.0532 0.0886
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0076 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0039 0.0225 0.0423
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0237 0.1299
Onchocerca volvulus 0.002 0.0076 0.0415
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0076 0.0076
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0024 0.0111 0.0608
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0025 0.0116 0.0118
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.021 0.0998
Brugia malayi Dopamine receptor 0.002 0.0076 0.0126
Leishmania major glycerol uptake protein, putative 0.0067 0.0446 0.0838
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0039 0.0225 0.1946
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1304 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0076 0.0076
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.1595 0.1595
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0076 0.0076
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0301 0.0301
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0076 0.0076
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0366
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0024 0.0111 0.0111
Loa Loa (eye worm) thyroid receptor interactor 0.0024 0.0111 0.0111
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0039 0.0225 0.1231
Onchocerca volvulus 0.0043 0.0261 0.1426
Echinococcus multilocularis snurportin 1 0.0335 0.251 0.251
Echinococcus granulosus sex peptide receptor 0.002 0.0076 0.0076
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0024 0.0111 0.0111
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0076 0.0078
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0076 0.0076
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0034 0.0184 0.159
Schistosoma mansoni glutamate receptor NMDA 0.0049 0.0301 0.0307
Echinococcus multilocularis growth factor receptor bound protein 2 0.0189 0.1383 0.1383
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0039 0.0225 0.1233
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0024 0.0111 0.0605
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0075 0.041
Echinococcus granulosus SHC transforming protein 3 0.0025 0.0116 0.0116
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0116 0.0192
Echinococcus granulosus tyrosine protein kinase Blk 0.003 0.0156 0.0156
Echinococcus multilocularis tyrosine kinase 0.003 0.0156 0.0156
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0015 0.0015
Schistosoma mansoni shc transforming protein 0.0025 0.0116 0.0118
Schistosoma mansoni metabotropic glutamate receptor 0.0252 0.1872 0.1908
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0121 0.0665
Brugia malayi hypothetical protein 0.002 0.0077 0.0128
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Onchocerca volvulus 0.0025 0.0116 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Onchocerca volvulus 0.0025 0.0116 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0342 0.0342
Brugia malayi Variant SH3 domain containing protein 0.0024 0.0111 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0017 0.0383
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0075 0.041
Echinococcus granulosus g protein coupled receptor 0.002 0.0076 0.0076
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0024 0.0111 0.0111
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0088 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0016 0.0366
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Leishmania major glycerol uptake protein, putative 0.0067 0.0446 0.0838
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Brugia malayi MBOAT family protein 0.0067 0.0446 0.0741
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0076 0.0076
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0169 0.0803
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0015 0.0015
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0782 0.5965 0.5965
Echinococcus granulosus peregrin 0.003 0.0158 0.0158
Onchocerca volvulus Putative cortactin 0.0024 0.0111 0.0605
Trichomonas vaginalis penicillin-binding protein, putative 0.001 0 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0008 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0179 0.1305 0.7149
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0025 0.0116 0.0115
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0039 0.0225 0.0225
Schistosoma mansoni tar DNA-binding protein 0.0067 0.044 0.0448
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0076 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Brugia malayi STAT protein, DNA binding domain containing protein 0.0025 0.0116 0.0192
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0089
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0037 0.0213 0.1841
Echinococcus multilocularis endophilin A3 0.0024 0.0111 0.0111
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0076 0.0076
Echinococcus granulosus o acyltransferase membrane bound domain 0.0067 0.0446 0.0446
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0024 0.0111 0.0208
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0342 0.0342
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0021 0.0088 0.0164
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Brugia malayi MBOAT family protein 0.0067 0.0446 0.0741
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0274 0.0274
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0088 0.0165
Brugia malayi TAR-binding protein 0.0067 0.044 0.0732
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0075 0.041
Brugia malayi Variant SH3 domain containing protein 0.0024 0.0111 0.0184
Entamoeba histolytica hypothetical protein 0.0025 0.0121 0.2725
Brugia malayi Calcitonin receptor-like protein seb-1 0.0079 0.0532 0.0886
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0076 0.0076
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0054 0.0342 0.0348
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0433 0.3271 0.3271
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0068 0.0113
Echinococcus granulosus atrial natriuretic peptide receptor 0.0049 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0108 0.0757 0.0757
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Echinococcus granulosus fch and double sh3 domains protein 2 0.0024 0.0111 0.0111
Schistosoma mansoni chromobox protein 0.0012 0.0016 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0008 0.0008
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0002
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.03
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0016 0.0366
Trypanosoma cruzi Heat shock protein 83, putative 0.0039 0.0225 0.0423
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0008 0.0041
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0021 0.0088 0.0164
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.002 0.0076 0.0078
Echinococcus granulosus tyrosine protein kinase Fps85D 0.003 0.0156 0.0156
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0076 0.0076
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0342 0.0342
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0076 0.0415
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0076 0.0076
Trichomonas vaginalis D-aminoacylase, putative 0.001 0 0.0003
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0039 0.0225 0.1946
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0039 0.0225 0.1946
Schistosoma mansoni suppressor of cytokine signaling 0.0025 0.0116 0.0118
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.002 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0025 0.0117 0.0117
Brugia malayi Endoplasmin precursor 0.0039 0.0225 0.0374
Brugia malayi Cytochrome P450 family protein 0.0012 0.0015 0.0024
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0034 0.0184 0.159
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Trichomonas vaginalis ran, putative 0.0023 0.0103 0.0566
Brugia malayi Inositol-1 0.0037 0.021 0.035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0274 0.028
Echinococcus granulosus fmrfamide receptor 0.002 0.0076 0.0076
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0895 0.0895
Trypanosoma brucei glycerol uptake protein, putative 0.0067 0.0446 0.0838
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0088 0.0087
Loa Loa (eye worm) p53BP2 0.0024 0.0111 0.0111
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0325 0.0611
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0225 0.0423
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0068 0.0068
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0039 0.0225 0.1946
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0076 0.0078
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0067 0.0446 0.0446
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0008 0.0008
Plasmodium falciparum phd finger protein, putative 0.003 0.0158 0.3551
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0069
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0117 0.0117
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0024 0.0111 0.0113
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0025 0.0116 0.0631
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0301 0.0301
Mycobacterium tuberculosis Possible two component sensor kinase 0.0039 0.0225 0.1946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0027 0.015
Schistosoma mansoni ran 0.0023 0.0103 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0076 0.0078
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0103 0.0103
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0588 0.4467 0.4554
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0169 0.0173
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0067 0.0446 0.0446
Echinococcus granulosus tyrosine protein kinase Srms 0.003 0.0156 0.0156
Schistosoma mansoni growth factor receptor-bound protein 0.0189 0.1383 0.141
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis SH2 domain containing protein 7 0.0025 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase Lyn 0.0054 0.0342 0.0342
Plasmodium vivax thioredoxin reductase, putative 0.0015 0.0039 0.0866
Trichomonas vaginalis set domain proteins, putative 0.0246 0.1825 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.021 0.0395
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0076 0.0076
Brugia malayi Guanylate kinase family protein 0.0024 0.0111 0.0184
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) SRC-1 0.0054 0.0342 0.0341
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0021 0.0088 0.0164
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0067 0.0446 0.2112
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0689 0.0689
Leishmania major phosphatidylinositol 3-kinase, putative 0.0021 0.0088 0.0164
Echinococcus multilocularis cpg binding protein 0.0035 0.0198 0.0198
Trichomonas vaginalis transmembrane protein nessy, putative 0.0067 0.0446 0.2442
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0039 0.0225 0.0423
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0253 0.0476
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.2258 0.4248
Schistosoma mansoni cpg binding protein 0.0035 0.0198 0.0202
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0034 0.0184 0.159
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0025 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Schistosoma mansoni transcription factor LCR-F1 0.002 0.0077 0.0079
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0076 0.0076
Brugia malayi Fes/CIP4 homology domain containing protein 0.0024 0.0111 0.0184
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0029 0.0149 0.0279
Schistosoma mansoni hypothetical protein 0.0025 0.0116 0.0118
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0015 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0068 0.0374
Echinococcus multilocularis Spectrin alpha actinin 0.0024 0.0111 0.0111
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0039 0.0225 0.1233
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.002 0.0077 0.0077
Toxoplasma gondii hypothetical protein 0.0067 0.0446 0.2112
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0016 0.0366
Echinococcus multilocularis expressed protein 0.0024 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0032 0.0169 0.0169
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0008 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0167 0.0314
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0155 0.0155
Brugia malayi Heterochromatin protein 1 0.0072 0.0482 0.0802
Echinococcus granulosus g protein coupled receptor 0.002 0.0076 0.0076
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0076 0.0076
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0039 0.0225 0.0225
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0067 0.0446 0.0446
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0024 0.0111 0.0111
Echinococcus granulosus tyrosine protein kinase shark 0.003 0.0156 0.0156
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0012 0.0017 0.0027
Brugia malayi Serotonin receptor 0.002 0.0076 0.0126
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0067 0.0446 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0181 0.1561
Brugia malayi Peripheral plasma membrane protein CASK 0.0024 0.0111 0.0184
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0076 0.0076
Echinococcus granulosus GPCR family 3 C terminal 0.0084 0.0573 0.0573
Schistosoma mansoni tensin-related 0.0025 0.0116 0.0118
Chlamydia trachomatis DNA gyrase subunit B 0.0039 0.0225 0.5
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0088 0.0146
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus granulosus SH2 domain containing protein 7 0.0025 0.0116 0.0116
Brugia malayi Variant SH3 domain containing protein 0.0049 0.0301 0.0501
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0008 0.0008
Schistosoma mansoni eps8-related protein 0.0024 0.0111 0.0113
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0025 0.0116 0.0116
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0067 0.0446 0.0446
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0067 0.0446 0.0446
Mycobacterium ulcerans putative regultory protein 0.0039 0.0225 0.1946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.012
Brugia malayi G-protein coupled receptor 0.002 0.0076 0.0126
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0158 0.075
Entamoeba histolytica hypothetical protein 0.002 0.0077 0.173
Giardia lamblia GTOR 0.0021 0.0088 0.3902
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0076 0.0076
Onchocerca volvulus 0.002 0.0076 0.0415
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0049 0.0301 0.0301
Brugia malayi heat shock protein 90 0.0039 0.0225 0.0374
Echinococcus multilocularis tyrosine protein kinase shark 0.003 0.0156 0.0156
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0076 0.0126
Echinococcus granulosus cpg binding protein 0.0035 0.0198 0.0198
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0039 0.0225 0.1946
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0121 0.0665
Loa Loa (eye worm) MBOAT family protein 0.0782 0.5965 0.5964
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0103 0.2318
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0008 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Plasmodium falciparum DNA topoisomerase 2 0.0039 0.0225 0.505
Loa Loa (eye worm) hypothetical protein 0.0084 0.0573 0.0573
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Echinococcus granulosus SH2 motif 0.0025 0.0116 0.0116
Schistosoma mansoni Dab2-interacting protein-like 0.0024 0.0111 0.0113
Echinococcus multilocularis sterol O acyltransferase 1 0.0067 0.0446 0.0446
Loa Loa (eye worm) SH2 domain-containing protein 0.0025 0.0116 0.0115
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0089
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0067 0.0446 0.0446
Echinococcus granulosus tensin 0.0025 0.0116 0.0116
Echinococcus multilocularis transfer RNA-Ala 0.0024 0.0111 0.0111
Loa Loa (eye worm) hhat protein 0.0067 0.0446 0.0445
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0067 0.0446 0.0446
Schistosoma mansoni hypothetical protein 0.0024 0.0111 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Brugia malayi Serotonin receptor 0.002 0.0076 0.0126
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Echinococcus multilocularis glutamate receptor 2 0.0049 0.0301 0.0301
Echinococcus granulosus g-protein coupled receptor 0.002 0.0076 0.0076
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0067 0.0446 0.0454
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0103 0.0103
Leishmania major extracellular receptor, putative 0.0049 0.0301 0.0565
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0089 0.0148
Echinococcus granulosus sterol O acyltransferase 1 0.0067 0.0446 0.0446
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0341 0.0341
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0167 0.0167
Echinococcus granulosus SH2 domain containing adapter protein F 0.0025 0.0116 0.0116
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0167
Leishmania major GTP-binding protein, putative 0.0023 0.0103 0.0194
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0076 0.0076
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.1029 0.1936
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0008 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0089
Chlamydia trachomatis DNA gyrase subunit B 0.0039 0.0225 0.5
Brugia malayi Dopamine receptor protein 1 0.002 0.0076 0.0126
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.003 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0076 0.0078
Plasmodium vivax heat shock protein 86, putative 0.0039 0.0225 0.505
Schistosoma mansoni heat shock protein 0.0039 0.0225 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0237 0.1301
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0008 0.0008
Echinococcus multilocularis peregrin 0.003 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Schistosoma mansoni tyrosine kinase 0.003 0.0156 0.0159
Brugia malayi jmjC domain containing protein 0.0038 0.0222 0.0369
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0008 0.0013
Brugia malayi larval opioid receptor 0.002 0.0076 0.0126
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0301 0.0301
Echinococcus granulosus suppressor of cytokine signaling 7 0.0025 0.0116 0.0116
Brugia malayi tRNA modification GTPase TrmE family protein 0.0025 0.0116 0.0192
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0025 0.0116 0.0116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0076 0.0078
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0075 0.041
Brugia malayi Receptor family ligand binding region containing protein 0.0133 0.0949 0.158
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0076 0.0076
Schistosoma mansoni amine GPCR 0.002 0.0076 0.0078
Onchocerca volvulus 0.003 0.0156 0.0852
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0008 0.0008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0025 0.0117 0.0117
Echinococcus granulosus allatostatin A receptor 0.002 0.0076 0.0076
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Schistosoma mansoni run and tbc1 domain containing 0.0024 0.0111 0.0113
Schistosoma mansoni ran 0.0023 0.0103 0.0105
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0025 0.0116 0.0116
Echinococcus granulosus metabotropic glutamate receptor 5 0.0637 0.4843 0.4843
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0301 0.0301
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0076 0.0078
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0021 0.0088 0.009
Trypanosoma cruzi trypanothione reductase, putative 0.0015 0.0039 0.0072
Schistosoma mansoni tyrosine kinase 0.0054 0.0342 0.0348
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Brugia malayi PHD-finger family protein 0.0012 0.0016 0.0026
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0253 0.0476
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.021 0.1153
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0075 0.041
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0021 0.0088 0.1971
Echinococcus multilocularis tensin 0.0025 0.0116 0.0116
Toxoplasma gondii hypothetical protein 0.0049 0.0301 0.1429
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0021 0.0088 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0008 0.0013
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0076 0.0126
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0089
Echinococcus granulosus neuropeptide s receptor 0.002 0.0076 0.0076
Echinococcus granulosus glutamate receptor 2 0.0049 0.0301 0.0301
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0169 0.0169
Brugia malayi protein-tyrosine kinase 0.003 0.0156 0.0259
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0088 0.0088
Brugia malayi jmjC domain containing protein 0.0099 0.0689 0.1146
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0067 0.0446 1
Schistosoma mansoni ap endonuclease 0.0019 0.0068 0.0069
Treponema pallidum alginate O-acetylation protein (algI) 0.0067 0.0446 1
Trichomonas vaginalis sensor histidine kinase, putative 0.0039 0.0225 0.1233
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Schistosoma mansoni GTPase activating protein 0.0025 0.0116 0.0118
Trypanosoma cruzi extracellular receptor, putative 0.0049 0.0301 0.0565
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Brugia malayi AF-10 protein 0.001 0.0001 0.0002
Echinococcus granulosus Spectrin alpha actinin 0.0024 0.0111 0.0111
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Schistosoma mansoni suppressor of cytokine signaling 0.0025 0.0116 0.0118
Schistosoma mansoni biogenic amine receptor 0.002 0.0076 0.0078
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0037 0.0213 0.1841
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0222 0.0222
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0103 0.049
Schistosoma mansoni growth factor receptor-bound protein 0.0189 0.1383 0.141
Echinococcus multilocularis thioredoxin glutathione reductase 0.0015 0.0039 0.0039
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0067 0.0446 0.2112
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0342 0.0342
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0895 0.0895
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0121 0.0228
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0008 0.0041
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Loa Loa (eye worm) protein-tyrosine kinase 0.0024 0.0111 0.0111
Schistosoma mansoni inositol monophosphatase 0.0037 0.021 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0049 0.0301 0.0307
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0039 0.0225 0.1946
Echinococcus multilocularis Chromo domain 0.0012 0.0016 0.0016
Brugia malayi Latrophilin receptor protein 2 0.0025 0.0117 0.0195
Schistosoma mansoni hypothetical protein 0.002 0.0076 0.0078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Schistosoma mansoni hypothetical protein 0.0067 0.0446 0.0454
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0039 0.0225 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0076 0.0078
Echinococcus multilocularis g protein coupled receptor 0.002 0.0076 0.0076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0089
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0084 0.0573 0.3141
Onchocerca volvulus 0.003 0.0156 0.0852
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Brugia malayi Tensin 0.0025 0.0116 0.0192
Loa Loa (eye worm) hypothetical protein 0.0698 0.5316 0.5316
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0076 0.0076
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0111 0.2489
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0244 0.181 0.3404
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0076 0.0076
Echinococcus multilocularis allatostatin A receptor 0.002 0.0076 0.0076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.1029 0.1936
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0342 0.0342
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0039 0.0225 0.4156
Echinococcus granulosus chromobox protein 2 0.0012 0.0016 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0199 0.0198
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Echinococcus granulosus signal transduction protein lnk realted 0.0025 0.0116 0.0116
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0103 0.0171
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.03
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.03
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0158 0.0161
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0637 0.4843 0.4843
Leishmania major glycerol uptake protein, putative 0.0067 0.0446 0.0838
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0181 0.802
Schistosoma mansoni importin beta-1 0.0031 0.0167 0.017
Echinococcus multilocularis tar DNA binding protein 0.0067 0.044 0.044
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0076 0.0076
Loa Loa (eye worm) glutamate receptor 0.0203 0.1496 0.1496
Brugia malayi Variant SH3 domain containing protein 0.0024 0.0111 0.0184
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0039 0.0225 0.1946
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0482 0.2642
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0068 0.303
Onchocerca volvulus 0.002 0.0076 0.0415
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0062 0.0407 0.3521
Mycobacterium ulcerans hypothetical protein 0.0159 0.1154 1
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0111 0.2489
Schistosoma mansoni fkbp-rapamycin associated protein 0.0012 0.0017 0.0017
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0024 0.0111 0.0111
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0689 0.0689
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0156
Trypanosoma cruzi DNA topoisomerase II, putative 0.0039 0.0225 0.0423
Schistosoma mansoni chromobox protein 0.0012 0.0016 0.0017
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0024 0.0111 0.0113
Echinococcus multilocularis somatostatin receptor 0.002 0.0076 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0034 0.019 0.019
Echinococcus multilocularis g protein coupled receptor 0.002 0.0076 0.0076
Brugia malayi sulfakinin receptor protein 0.002 0.0076 0.0126
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0015 0.0039 0.033
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0076 0.0078
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0024 0.0111 0.0111
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0016 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.001 0 0.0001
Brugia malayi MH2 domain containing protein 0.0126 0.0895 0.149
Echinococcus granulosus growth factor receptor bound protein 2 0.0189 0.1383 0.1383
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0001 0.0006
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0015 0.0028
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0076 0.0126
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0016 0.0027
Plasmodium falciparum thioredoxin reductase 0.0015 0.0039 0.0866
Schistosoma mansoni cell polarity protein 0.0024 0.0111 0.0113
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0016 0.0089
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0024 0.0111 0.0113
Brugia malayi RNA binding protein 0.0067 0.044 0.0732
Brugia malayi Bromodomain containing protein 0.003 0.0158 0.0263
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0067 0.0446 0.0454
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Toxoplasma gondii exonuclease III APE 0.0019 0.0068 0.0323
Plasmodium vivax hypothetical protein, conserved 0.003 0.0158 0.3551
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Plasmodium vivax SET domain protein, putative 0.0032 0.0169 0.3803
Echinococcus multilocularis SHC transforming protein 3 0.0025 0.0116 0.0116
Echinococcus multilocularis neuropeptide receptor A26 0.002 0.0076 0.0076
Schistosoma mansoni histamine h1 receptor 0.002 0.0076 0.0078
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.003 0.0156 0.0156
Mycobacterium ulcerans two component regulator - sensor kinase 0.0039 0.0225 0.1946
Schistosoma mansoni neuropeptide receptor 0.002 0.0076 0.0078
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0068 0.153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Schistosoma mansoni tensin 0.0025 0.0116 0.0118
Schistosoma mansoni tyrosine kinase 0.0054 0.0341 0.0348
Mycobacterium tuberculosis Probable oxidoreductase 0.0037 0.0213 0.1841
Echinococcus granulosus g protein coupled receptor 0.002 0.0076 0.0076
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0024 0.0111 0.0113
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0021 0.0088 0.0164
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0029 0.0149 0.0151
Echinococcus multilocularis serotonin receptor 0.002 0.0076 0.0076
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0034 0.019 0.019
Brugia malayi neuropeptide F receptor 0.002 0.0076 0.0126
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0274 0.0274
Schistosoma mansoni sterol O-acyltransferase 1 0.0067 0.0446 0.0454
Schistosoma mansoni pyruvate dehydrogenase 0.0698 0.5316 0.5419
Brugia malayi Importin beta-1 subunit 0.0031 0.0167 0.0278
Echinococcus granulosus geminin 0.0114 0.0808 0.0808
Trichomonas vaginalis receptor histidine kinase, putative 0.0039 0.0225 0.1233
Plasmodium falciparum endoplasmin, putative 0.0039 0.0225 0.505
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0049 0.0301 0.05
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.001 0 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0111 0.0208
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0027
Onchocerca volvulus 0.0033 0.0183 0.1003
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0013 0.0027 0.0051
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0189 0.1383 0.1383
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.2258 0.4248
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0237 0.1301
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0103 0.4591
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0014 0.0013
Brugia malayi Pre-SET motif family protein 0.0216 0.1595 0.2655
Leishmania major DNA topoisomerase ii 0.0039 0.0225 0.0423
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0068 0.0128
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0652 0.4961 0.4961
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0075 0.041
Brugia malayi AKH receptor 0.002 0.0076 0.0126
Schistosoma mansoni opsin-like receptor 0.002 0.0076 0.0078
Loa Loa (eye worm) hypothetical protein 0.0052 0.0325 0.0324
Loa Loa (eye worm) SH2 domain-containing protein 0.0025 0.0116 0.0115
Schistosoma mansoni heat shock protein 0.0039 0.0225 0.0229
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0012 0.0017 0.0017
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0037 0.0213 0.9458
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0116 0.0192
Echinococcus granulosus receptor type guanylyl cyclase 0.0054 0.0341 0.0341
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0253 0.0476
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Toxoplasma gondii FATC domain-containing protein 0.0029 0.0149 0.0704
Schistosoma mansoni dreadlocks/dock 0.0024 0.0111 0.0113
Echinococcus multilocularis serine protein kinase ATM 0.0029 0.0149 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Echinococcus multilocularis tyrosine protein kinase Srms 0.003 0.0156 0.0156
Trypanosoma cruzi DNA topoisomerase II, putative 0.0039 0.0225 0.0423
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0076 0.0076
Trichomonas vaginalis receptor histidine kinase, putative 0.0039 0.0225 0.1233
Mycobacterium tuberculosis Probable dehydrogenase 0.0034 0.0184 0.159
Brugia malayi Protein kinase domain containing protein 0.003 0.0156 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0024 0.0111 0.0111
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0039 0.0225 0.0374
Entamoeba histolytica protein kinase, putative 0.0025 0.0116 0.2595
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0088 0.0087
Schistosoma mansoni hypothetical protein 0.0045 0.0273 0.0278
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0076 0.0078
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0342 0.0342
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0025 0.0116 0.0116
Onchocerca volvulus Alhambra homolog 0.003 0.0158 0.0865
Brugia malayi SRC-1 0.0054 0.0342 0.0569
Echinococcus granulosus neuropeptide receptor 0.002 0.0076 0.0076
Echinococcus granulosus neuropeptide receptor A26 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0225 0.1233
Loa Loa (eye worm) RNA binding protein 0.0067 0.044 0.0439
Schistosoma mansoni coup transcription factor 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0001 0.0006
Echinococcus granulosus tyrosine kinase 0.003 0.0156 0.0156
Brugia malayi Myosin tail family protein 0.0024 0.0111 0.0184
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0016 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0076 0.0076
Schistosoma mansoni endoplasmin 0.0039 0.0225 0.0229
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0075 0.041
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0024 0.0111 0.0111
Onchocerca volvulus 0.002 0.0076 0.0415
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0068 0.0587
Echinococcus multilocularis tyrosine kinase 0.0054 0.0341 0.0341
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0103 0.2318
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0067 0.0446 1
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0016 0.0017
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0025 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus granulosus chromobox protein 1 0.0072 0.0482 0.0482
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.021 0.0395
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0025 0.0116 0.0116
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0225 0.0423
Brugia malayi diacylglycerol acyltransferase 0.0067 0.0446 0.0741
Brugia malayi Variant SH3 domain containing protein 0.0049 0.0301 0.0501
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0008 0.0008
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0067 0.0446 0.0454
Onchocerca volvulus 0.002 0.0076 0.0415
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.021 0.0395
Schistosoma mansoni hypothetical protein 0.0335 0.251 0.2558
Onchocerca volvulus 0.003 0.0156 0.0852
Mycobacterium leprae Probable two-component sensor kinase 0.0039 0.0225 1
Schistosoma mansoni pyruvate dehydrogenase 0.0659 0.5016 0.5114
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0008 0.0008
Echinococcus granulosus microtubule associated protein 2 0.0714 0.5443 0.5443
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0088 0.0164
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Leishmania major hypothetical protein, conserved 0.0039 0.0225 0.0423
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0008 0.0013
Entamoeba histolytica hypothetical protein 0.002 0.0077 0.173
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0076 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0067 0.044 0.0448
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Echinococcus multilocularis zinc finger protein 0.0714 0.5444 0.5444
Toxoplasma gondii ABC1 family protein 0.001 0 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0183 0.0183
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0021 0.0088 0.009
Brugia malayi protein-tyrosine kinase 0.0024 0.0111 0.0184
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0067 0.0446 0.0446
Brugia malayi kinase, mitochondrial precursor 0.0698 0.5316 0.8852
Echinococcus granulosus intersectin 2 0.0024 0.0111 0.0111
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0008 0.0008
Echinococcus multilocularis neuropeptide receptor 0.002 0.0076 0.0076
Onchocerca volvulus 0.002 0.0076 0.0415
Plasmodium vivax DNA topoisomerase II, putative 0.0039 0.0225 0.505
Echinococcus granulosus o acyltransferase membrane bound domain 0.0067 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Echinococcus granulosus Chromo domain 0.0012 0.0016 0.0016
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0169 0.0169
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0482 0.0491
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0103 0.0194
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0076 0.0078
Leishmania major cytochrome p450-like protein 0.0012 0.0015 0.0028
Echinococcus multilocularis SH2 motif 0.0025 0.0116 0.0116
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0016 0.0366
Brugia malayi CXXC zinc finger family protein 0.0033 0.0183 0.0305
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0039 0.0225 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Brugia malayi SH2 domain containing protein 0.003 0.0156 0.0259
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0012 0.0017 0.0031
Echinococcus granulosus suppressor of cytokine signaling 6 0.0025 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Loa Loa (eye worm) guanylate kinase 0.0024 0.0111 0.0111
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0025 0.0116 0.0116
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0225 0.0423
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.021 0.0395
Brugia malayi RE15519p 0.002 0.0076 0.0126
Echinococcus multilocularis heat shock protein 0.0039 0.0225 0.0225
Loa Loa (eye worm) TK protein kinase 0.003 0.0156 0.0156
Echinococcus granulosus snurportin 1 0.0335 0.251 0.251
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Echinococcus granulosus GPCR family 2 0.0025 0.0117 0.0117
Trypanosoma cruzi GUP1, putative 0.0067 0.0446 0.0838
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Schistosoma mansoni hypothetical protein 0.003 0.0158 0.0161
Onchocerca volvulus 0.0027 0.0134 0.0729
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0067 0.0446 0.0445
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0169 0.0173
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis nmda type glutamate receptor 0.0049 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Leishmania major glycerol uptake protein, putative 0.0067 0.0446 0.0838
Loa Loa (eye worm) heat shock protein 90 0.0039 0.0225 0.0225
Loa Loa (eye worm) TK/ABL protein kinase 0.1304 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Onchocerca volvulus 0.0049 0.0301 0.1646
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0068 0.0068
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0366
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0039 0.0225 0.1946
Mycobacterium ulcerans two component sensor kinase MprB 0.0039 0.0225 0.1946
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0025 0.0116 0.2595
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0366
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.021 0.9073
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Onchocerca volvulus 0.002 0.0076 0.0415
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.1029 0.1936
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0076 0.0076
Toxoplasma gondii heat shock protein HSP90 0.0039 0.0225 0.1067
Brugia malayi chromobox protein homolog 3 0.004 0.0237 0.0395
Schistosoma mansoni cpg binding protein 0.0033 0.0183 0.0187
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0016 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0089
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Echinococcus granulosus importin subunit beta 1 0.0031 0.0167 0.0167
Plasmodium vivax glutathione reductase, putative 0.0015 0.0039 0.0866
Brugia malayi hypothetical protein 0.003 0.0156 0.0259
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Plasmodium falciparum JmjC domain-containing protein, putative 0.001 0 0.0008
Brugia malayi Pre-SET motif family protein 0.0032 0.0169 0.0282
Echinococcus granulosus zinc finger protein 0.0714 0.5444 0.5444
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0067 0.0446 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Brugia malayi Protein kinase domain containing protein 0.003 0.0156 0.0259
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0008 0.0013
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0116 0.0115
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0076 0.0078
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0016 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0031 0.0031
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0076 0.0076
Echinococcus granulosus serine protein kinase ATM 0.0029 0.0149 0.0149
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Schistosoma mansoni tyrosine kinase 0.0054 0.0342 0.0348
Schistosoma mansoni hypothetical protein 0.0114 0.0808 0.0824
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0283 0.211 1
Leishmania major hypothetical protein, conserved 0.0024 0.0111 0.0208
Onchocerca volvulus 0.002 0.0076 0.0415
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0008 0.0008
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0016 0.0027
Brugia malayi Hhat protein 0.0067 0.0446 0.0741
Loa Loa (eye worm) hypothetical protein 0.0067 0.0446 0.0445
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.0156 0.0156
Schistosoma mansoni cpg binding protein 0.0035 0.0198 0.0202
Schistosoma mansoni hypothetical protein 0.0114 0.0808 0.0824
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0301 0.0301
Onchocerca volvulus 0.003 0.0156 0.0852
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0184 0.1343 0.2237
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0008 0.0008
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0698 0.5316 0.5316
Trypanosoma brucei DNA topoisomerase ii 0.0039 0.0225 0.0423
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0025 0.0116 0.0118
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0076 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Loa Loa (eye worm) thioredoxin reductase 0.0015 0.0039 0.0038
Schistosoma mansoni SH2A 0.0025 0.0116 0.0118
Schistosoma mansoni tensin-related 0.0025 0.0116 0.0118
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Onchocerca volvulus 0.0025 0.0116 0.0631
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0021 0.0088 0.0164
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Schistosoma mansoni pyruvate dehydrogenase 0.0659 0.5016 0.5114
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0076 0.0126
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0008 0.0008
Schistosoma mansoni inositol monophosphatase 0.0037 0.021 0.0215
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0076 0.0076
Brugia malayi SH2 domain containing protein 0.003 0.0156 0.0259
Schistosoma mansoni amine GPCR 0.002 0.0076 0.0078
Onchocerca volvulus 0.002 0.0076 0.0415
Loa Loa (eye worm) SH2 domain-containing protein 0.0025 0.0116 0.0115
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0016 0.0027
Brugia malayi MBOAT family protein 0.0067 0.0446 0.0741
Schistosoma mansoni nck2/grb4 0.0049 0.0301 0.0307
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0025 0.0116 0.0116
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0103 0.0194
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni microtubule-associated protein tau 0.0714 0.5443 0.5549
Schistosoma mansoni tar DNA-binding protein 0.0067 0.044 0.0448
Onchocerca volvulus 0.003 0.0156 0.0852
Brugia malayi Protein kinase domain containing protein 0.003 0.0156 0.0259
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0008 0.0008
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0117 0.022
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0054 0.0341 0.1867
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.004 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0008 0.0008
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0034 0.0184 0.159
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0016 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0008 0.0013
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0025 0.0116 0.0118
Onchocerca volvulus 0.0032 0.017 0.0929
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0225 0.0423
Entamoeba histolytica unconventional myosin IB 0.0024 0.0111 0.2489
Echinococcus multilocularis g protein coupled receptor 0.002 0.0076 0.0076
Echinococcus multilocularis serotonin receptor 0.002 0.0076 0.0076
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0039 0.0225 0.1946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0049 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus granulosus Chromobox protein 3 0.0012 0.0016 0.0016
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0031 0.0032
Brugia malayi Variant SH3 domain containing protein 0.0024 0.0111 0.0184
Mycobacterium tuberculosis Probable reductase 0.0034 0.0184 0.159
Echinococcus granulosus hypothetical protein 0.002 0.0076 0.0076
Echinococcus granulosus chromobox protein 1 0.0072 0.0482 0.0482
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0039 0.0225 0.4156
Echinococcus multilocularis neuropeptide receptor 0.002 0.0076 0.0076
Plasmodium vivax DNA gyrase subunit B, putative 0.0039 0.0225 0.505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Brugia malayi G protein-coupled receptor 0.002 0.0076 0.0126
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0039 0.0225 0.1946
Loa Loa (eye worm) hypothetical protein 0.0079 0.0532 0.0532
Echinococcus granulosus expressed conserved protein 0.0025 0.0116 0.0116
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0025 0.0117 0.0195
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0076 0.0076
Echinococcus multilocularis 0.0025 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0067 0.0446 0.0445
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0039 0.0225 0.0374
Schistosoma mansoni tyrosine kinase 0.0054 0.0342 0.0348
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0048 0.0261
Brugia malayi ecdysteroid receptor 0.0011 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0149 0.0814
Echinococcus granulosus neuropeptide receptor 0.002 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0054 0.0342 0.0342
Schistosoma mansoni hypothetical protein 0.002 0.0077 0.0079
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0002
Brugia malayi RNA, U transporter 1 0.0089 0.0614 0.1021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0111 0.0208
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Echinococcus multilocularis heat shock protein 90 0.0039 0.0225 0.0225
Brugia malayi Variant SH3 domain containing protein 0.0024 0.0111 0.0184
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0076 0.0126
Onchocerca volvulus 0.002 0.0076 0.0415
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0225 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0406 0.0406
Echinococcus multilocularis nostrin 0.0024 0.0111 0.0111
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0222 0.0226
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0079 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Onchocerca volvulus 0.0024 0.0111 0.0605
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0076 0.0076
Brugia malayi MBOAT family protein 0.0782 0.5965 0.9932
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0146 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Loa Loa (eye worm) helicase 0.0012 0.0016 0.0016
Trypanosoma cruzi target of rapamycin kinase 3 0.0021 0.0088 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Echinococcus multilocularis orexin receptor type 2 0.002 0.0076 0.0076
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0261 0.1431
Entamoeba histolytica protein kinase rad3, putative 0.0012 0.0017 0.0378
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0008 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0008 0.0008
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0301 0.0301
Brugia malayi Metabotropic glutamate receptor precursor. 0.0517 0.392 0.6527
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0342 0.0342
Echinococcus multilocularis SH2 motif 0.0025 0.0116 0.0116
Echinococcus granulosus N chimaerin 0.0025 0.0116 0.0116
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0167 0.0314
Brugia malayi MBOAT family protein 0.0067 0.0446 0.0741
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0225 0.0423
Leishmania major hypothetical protein, conserved 0.0067 0.0446 0.0838
Echinococcus granulosus nmda type glutamate receptor 0.0049 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Plasmodium vivax JmjC domain containing protein 0.001 0 0.0008
Echinococcus granulosus src region 0.0024 0.0111 0.0111
Schistosoma mansoni chromobox protein 0.0072 0.0482 0.0492
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0039 0.0225 0.1067
Echinococcus granulosus tyrosine protein kinase Src42A 0.0025 0.0116 0.0116
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0039 0.0225 0.1231
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0008 0.0008
Echinococcus granulosus heat shock protein 0.0039 0.0225 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Brugia malayi Tyrosine-protein kinase abl-1 0.0787 0.6005 1
Leishmania major developmentally regulated phosphoprotein-like protein 0.0698 0.5316 1
Echinococcus multilocularis N chimaerin 0.0025 0.0116 0.0116
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0039 0.0225 1
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0244 0.181 0.8579
Schistosoma mansoni tyrosine kinase 0.0054 0.0341 0.0348
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0025 0.0116 0.0118
Loa Loa (eye worm) STAT protein 0.0025 0.0116 0.0115
Echinococcus granulosus tyrosine kinase 0.0054 0.0341 0.0341
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0158 0.0158
Schistosoma mansoni myosin xvIII 0.002 0.0076 0.0078
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0341 0.0341
Schistosoma mansoni signal transduction protein lnk-related 0.0025 0.0116 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0158 0.075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Brugia malayi hypothetical protein 0.0012 0.0016 0.0027
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0225 0.0423
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0039 0.0225 0.1946
Echinococcus granulosus orexin receptor type 2 0.002 0.0076 0.0076
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0039 0.0225 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0116 0.0192
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0008 0.0008
Schistosoma mansoni zinc finger protein 0.0782 0.5965 0.608
Plasmodium vivax hypothetical protein, conserved 0.001 0 0.0011
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0008 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0017 0.0383
Schistosoma mansoni neuropeptide receptor 0.002 0.0076 0.0078
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.03
Echinococcus granulosus heat shock protein 90 0.0039 0.0225 0.0225
Brugia malayi follicle stimulating hormone receptor 0.002 0.0076 0.0126
Onchocerca volvulus 0.003 0.0156 0.0852
Echinococcus granulosus serotonin receptor 0.002 0.0076 0.0076
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0015 0.0028
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.2258 0.4248
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0158 0.0158
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0039 0.0225 0.1946
Entamoeba histolytica SH2-protein kinase domain containing protein 0.003 0.0156 0.3501
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0012 0.0017 0.0017
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Brugia malayi G-protein coupled receptor 0.002 0.0076 0.0126
Onchocerca volvulus 0.0012 0.0016 0.0087
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0067 0.0446 0.0446
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0076 0.0076
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0274 0.0456
Loa Loa (eye worm) hypothetical protein 0.0492 0.3729 0.3729
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0076 0.0076
Mycobacterium tuberculosis Probable two component sensor kinase 0.0039 0.0225 0.1946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0024 0.0111 0.0111
Entamoeba histolytica hypothetical protein 0.0067 0.0446 1
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0244 0.181 0.3404
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0076 0.0126
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Onchocerca volvulus 0.0024 0.0111 0.0605
Trypanosoma brucei developmentally regulated phosphoprotein 0.0698 0.5316 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0043 0.0238
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0013 0.0027 0.013
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0468 0.3544 0.5901
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0084 0.0573 0.0954
Brugia malayi Protein kinase domain containing protein 0.003 0.0156 0.0259
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0031 0.0031
Brugia malayi GnHR receptor homolog 0.002 0.0076 0.0126
Schistosoma mansoni tyrosine kinase 0.0054 0.0342 0.0348
Echinococcus multilocularis SH2 motif 0.0025 0.0116 0.0116
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0068 0.153
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0115
Echinococcus multilocularis GPCR, family 2 0.0025 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0025 0.0116 0.0116
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0133 0.0949 0.0949
Trypanosoma brucei conserved protein 0.0024 0.0111 0.0208
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0076 0.0076
Entamoeba histolytica BAR/SH3 domain containing protein 0.0024 0.0111 0.2489
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0076 0.0076
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Echinococcus granulosus tar DNA binding protein 0.0067 0.044 0.044
Echinococcus granulosus endophilin A3 0.0024 0.0111 0.0111
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0133 0.0949 0.0949
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Entamoeba histolytica Ran family GTPase 0.0023 0.0103 0.2318
Trichomonas vaginalis porcupine, putative 0.0067 0.0446 0.2442
Brugia malayi nuclear hormone receptor 0.0011 0.0008 0.0013
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0225 0.505
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0008 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0076 0.0076
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0025 0.0116 0.0631
Echinococcus granulosus somatostatin receptor 0.002 0.0076 0.0076
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0068 0.153
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0088 0.0164
Loa Loa (eye worm) glutathione reductase 0.0015 0.0039 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0446 0.2442
Schistosoma mansoni endoplasmin 0.0039 0.0225 0.0229
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.03
Onchocerca volvulus 0.0024 0.0111 0.0605
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0076 0.0078
Brugia malayi Spectrin alpha chain 0.0024 0.0111 0.0184
Schistosoma mansoni sorbin 0.0024 0.0111 0.0113
Schistosoma mansoni tyrosine kinase 0.128 0.9809 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0261 0.1429
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0008 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Schistosoma mansoni opsin-like receptor 0.002 0.0076 0.0078
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0025 0.0116 0.0115
Schistosoma mansoni amine GPCR 0.002 0.0076 0.0078
Loa Loa (eye worm) TAR-binding protein 0.0067 0.044 0.0439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Loa Loa (eye worm) TOPoisomerase family member 0.0039 0.0225 0.0225
Brugia malayi SH2 domain containing protein 0.0025 0.0116 0.0192
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0012 0.0016 0.0017
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0039 0.0225 0.1067
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0169 0.0173
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.021 0.1153
Giardia lamblia Pms1-like protein 0.0039 0.0225 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0342 0.0342
Onchocerca volvulus 0.002 0.0076 0.0415
Plasmodium vivax endoplasmin, putative 0.0039 0.0225 0.505
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0021 0.0088 0.0164
Trichomonas vaginalis D-aminoacylase, putative 0.001 0 0.0003
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0039 0.0225 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0076 0.0076
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0014 0.0014
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Brugia malayi putative neuropeptide receptor 0.002 0.0076 0.0126
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0076 0.0076
Echinococcus multilocularis sex peptide receptor 0.002 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0342 0.0342
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0008 0.0008
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0039 0.0225 0.1946
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0076 0.0076
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0207 0.0207
Trichomonas vaginalis D-aminoacylase, putative 0.001 0 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0008 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0076 0.0078
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0088 0.0088
Brugia malayi hypothetical protein 0.002 0.0076 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0446 0.2442
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0335 0.251 0.2509
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.001 0 0.0001
Echinococcus granulosus thioredoxin glutathione reductase 0.0015 0.0039 0.0039
Echinococcus multilocularis GPCR, family 3, C terminal 0.0084 0.0573 0.0573
Schistosoma mansoni adapter molecule crk 0.0049 0.0301 0.0307
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0111 0.0608
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0067 0.0446 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0067 0.0446 0.0454
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0054 0.0341 0.0341
Brugia malayi Cytochrome P450 family protein 0.0012 0.0015 0.0024
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0076 0.0076
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0076 0.0415
Mycobacterium tuberculosis Conserved protein 0.0039 0.0225 0.1946
Schistosoma mansoni vav2 0.0025 0.0116 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0092
Trichomonas vaginalis p67phox protein, putative 0.0024 0.0111 0.0608
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0027 0.015
Echinococcus multilocularis fmrfamide receptor 0.002 0.0076 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0149 0.0247
Loa Loa (eye worm) hypothetical protein 0.002 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.002 0.0076 0.0078
Mycobacterium leprae Probable two component sensor kinase MprB 0.0039 0.0225 1
Trichomonas vaginalis endoplasmin, putative 0.0039 0.0225 0.1233
Schistosoma mansoni amine GPCR 0.002 0.0076 0.0078
Echinococcus granulosus epidermal growth factor receptor kinase 0.0024 0.0111 0.0111
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0103 0.0194
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0274 0.0274
Echinococcus multilocularis glutamate receptor 2 0.0049 0.0301 0.0301
Brugia malayi neuropeptide F receptor 0.002 0.0076 0.0126
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0076 0.0076
Leishmania major heat shock protein 83-1 0.0039 0.0225 0.0423
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.021 0.182
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0068 0.0128
Leishmania major trypanothione reductase 0.0015 0.0039 0.0072
Echinococcus granulosus o acyltransferase membrane bound domain 0.0067 0.0446 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0146 0.0801
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0008 0.0008
Loa Loa (eye worm) endoplasmin 0.0039 0.0225 0.0225
Brugia malayi metabotropic glutamate receptor type 2 0.0252 0.1872 0.3117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0008 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0446 0.2442
Brugia malayi Receptor family ligand binding region containing protein 0.0054 0.0341 0.0567
Brugia malayi ORL1-like opioid receptor 0.002 0.0076 0.0126
Echinococcus granulosus dnaJ subfamily B 0.0476 0.3605 0.3605
Schistosoma mansoni sorting nexin 0.0024 0.0111 0.0113
Schistosoma mansoni metabotropic glutamate receptor 0.0433 0.3271 0.3335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0088 0.0481
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0366
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0342 0.0342
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0039 0.0225 0.1233
Echinococcus multilocularis tensin 0.0025 0.0116 0.0116
Echinococcus granulosus SH2 motif 0.0025 0.0116 0.0116
Trypanosoma cruzi glycerol uptake protein, putative 0.0067 0.0446 0.0838
Brugia malayi Protein kinase domain containing protein 0.003 0.0156 0.0259
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0782 0.5965 0.5965
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0274 0.0274
Schistosoma mansoni tensin 0.0025 0.0116 0.0118
Onchocerca volvulus 0.0067 0.0446 0.244
Entamoeba histolytica hypothetical protein 0.0024 0.0111 0.2489
Echinococcus multilocularis c src tyrosine kinase 0.0054 0.0342 0.0342
Trypanosoma brucei heat shock protein, putative 0.0039 0.0225 0.0423
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0076 0.0076
Plasmodium falciparum importin beta, putative 0.0031 0.0167 0.3753
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0366
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 4.32 uM Inhibition of Grb2 SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain ChEMBL. 10450965
IC50 (binding) = 4.32 uM Inhibition of Growth factor receptor bound protein 2 SH2 domain binding to phospho-EGFR by ELISA ChEMBL. 9873638
IC50 (binding) = 4.32 uM Inhibition of Grb2 SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain ChEMBL. 10450965
IC50 (binding) = 4.32 uM Inhibition of Growth factor receptor bound protein 2 SH2 domain binding to phospho-EGFR by ELISA ChEMBL. 9873638

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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