Detailed information for compound 939753

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 296.403 | Formula: C20H24O2
  • H donors: 0 H acceptors: 2 LogP: 3.07 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1C=C[C@]2(C(=C1)C(=C)C[C@@H]1[C@@H]2CC[C@]2([C@@H]1CCC2=O)C)C
  • InChi: 1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15+,16-,19+,20-/m0/s1
  • InChiKey: BFYIZQONLCFLEV-RQQUZUBOSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cruzipain precursor, putative 0.014 0.0614 0.0971
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0105 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Trypanosoma cruzi acetyl-CoA carboxylase 0.1261 0.6162 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0085 0.0629
Echinococcus granulosus cathepsin l1 0.0025 0.0046 0.0046
Treponema pallidum pyruvate carboxylase subunit B 0.0071 0.0277 0.5
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0276 0.129 0.3213
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0096 0.0096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0085 0.0085
Brugia malayi Pre-SET motif family protein 0.0253 0.1174 0.1217
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0026 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0105 0.0661
Entamoeba histolytica hypothetical protein 0.0043 0.0139 0.0748
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0018 0.0018
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1474 0.7216 1
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0776 0.3762 0.3762
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0071 0.0277 0.0287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.018 0.018
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0276 0.129 0.3213
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0776 0.3762 1
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.007 0.0073
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0085 0.0085
Brugia malayi hypothetical protein 0.0017 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0085 0.0088
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0776 0.3762 0.3762
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0119 0.0764
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0071 0.0277 0.0423
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0139 0.0139
Echinococcus granulosus cathepsin l1 0.0037 0.0105 0.0105
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0776 0.3762 0.6094
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0085 0.0085
Schistosoma mansoni smad1 5 8 and 0.0025 0.0046 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0085 0.0088
Leishmania major carboxylase, putative 0.0776 0.3762 0.3696
Brugia malayi Cathepsin L-like precursor 0.0037 0.0105 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Onchocerca volvulus 0.0032 0.0085 0.0629
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0085 0.0085
Entamoeba histolytica hypothetical protein 0.0043 0.0139 0.0748
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0085 0.0085
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0175 0.0792 0.0792
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0071 0.0277 0.0174
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0519 0.0418
Brugia malayi Cathepsin L-like precursor 0.0037 0.0105 0.0109
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0085 0.0088
Entamoeba histolytica cysteine protease, putative 0.0037 0.0105 0.054
Echinococcus multilocularis musashi 0.0029 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0062 0.0233 0.0233
Brugia malayi Cathepsin L-like precursor 0.0037 0.0105 0.0109
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0175 0.0792 0.0776
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0164 0.0733 0.076
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0085 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Echinococcus multilocularis Biotin lipoyl attachment 0.0071 0.0277 0.0277
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0105 0.0446 0.0462
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0085 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0362 0.1715 0.1778
Echinococcus granulosus intermediate filament protein 0.0029 0.007 0.007
Brugia malayi hypothetical protein 0.0517 0.2482 0.2573
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.0467 0.0731
Schistosoma mansoni hypothetical protein 0.0052 0.018 0.018
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0105 0.0109
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0085 0.0085
Onchocerca volvulus 0.0029 0.007 0.0522
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0046 0.0046
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0276 0.129 0.1197
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0776 0.3762 0.3751
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0071 0.0277 0.0287
Leishmania major cathepsin L-like protease 0.014 0.0614 0.0514
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0119 0.0119
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0008 0.0008
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0347 0.1643 1
Brugia malayi nuclear receptor NHR-88 0.0032 0.0085 0.0088
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0119 0.0102
Schistosoma mansoni hypothetical protein 0.0052 0.018 0.018
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0071 0.0277 0.0434
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0071 0.0277 0.0277
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0071 0.0277 0.0361
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0027 0.0028
Loa Loa (eye worm) cysteine protease 0.0037 0.0105 0.0109
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0085 0.0085
Plasmodium falciparum cysteine proteinase falcipain 3 0.0037 0.0105 0.0122
Brugia malayi Smad1 0.0025 0.0046 0.0048
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0172 0.0178
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0276 0.129 0.3213
Leishmania major acetyl-CoA carboxylase, putative 0.2037 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Echinococcus multilocularis survival motor neuron protein 1 0.0517 0.2482 0.2482
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0175 0.0792 0.1847
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1346 1
Onchocerca volvulus Cathepsin F homolog 0.0037 0.0105 0.0784
Brugia malayi MH1 domain containing protein 0.0025 0.0046 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0046 0.021
Echinococcus granulosus lamin 0.0029 0.007 0.007
Trichomonas vaginalis esterase, putative 0.0039 0.0119 0.0764
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0071 0.0277 0.0434
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0071 0.0277 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.0614 0.0971
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Trypanosoma brucei acetyl-CoA carboxylase 0.2037 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Leishmania major carbamoyl-phosphate synthase, putative 0.0175 0.0792 0.0694
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.0614 0.0971
Echinococcus granulosus cathepsin L cysteine proteinase 0.0037 0.0105 0.0105
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0276 0.129 0.129
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0085 0.0088
Brugia malayi Latrophilin receptor protein 2 0.0052 0.018 0.0187
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0071 0.0277 0.0277
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0276 0.129 0.129
Schistosoma mansoni hypothetical protein 0.0052 0.018 0.018
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0071 0.0277 0.0277
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0071 0.0277 0.0277
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0071 0.0277 0.0423
Schistosoma mansoni survival motor neuron protein 0.0105 0.0446 0.0446
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0009 0.0009
Loa Loa (eye worm) Smad1 0.0025 0.0046 0.0048
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0085 0.0629
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0047
Onchocerca volvulus 0.0037 0.0105 0.0784
Trypanosoma brucei unspecified product 0.051 0.2447 0.2434
Onchocerca volvulus 0.0025 0.0046 0.0339
Leishmania major cathepsin L-like protease 0.014 0.0614 0.0514
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0776 0.3762 0.3696
Echinococcus granulosus survival motor neuron protein 1 0.0517 0.2482 0.2482
Loa Loa (eye worm) hypothetical protein 0.0112 0.0477 0.0495
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0085 0.0088
Loa Loa (eye worm) hypothetical protein 0.0052 0.018 0.0187
Echinococcus granulosus cysteine protease 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0068 0.007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0085 0.0088
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0085 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0085 0.0088
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.1966 0.9647 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Echinococcus granulosus Biotin lipoyl attachment 0.0071 0.0277 0.0277
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0071 0.0277 0.0277
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0071 0.0277 0.0277
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0018 0.0018
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.012 0.0773
Loa Loa (eye worm) hypothetical protein 0.0071 0.0277 0.0287
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0276 0.129 0.1274
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0071 0.0277 0.026
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0071 0.0277 0.0277
Schistosoma mansoni coup transcription factor 0.0032 0.0085 0.0085
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0071 0.0277 0.0423
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.2037 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0105 0.0784
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0776 0.3762 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0105 0.0109
Echinococcus granulosus microtubule associated protein 2 0.1509 0.7388 0.7388
Brugia malayi CXXC zinc finger family protein 0.0063 0.0235 0.0244
Loa Loa (eye worm) intermediate filament protein 0.0029 0.007 0.0073
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0105 0.0784
Brugia malayi MH2 domain containing protein 0.0025 0.0046 0.0048
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0071 0.0277 0.0174
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0003 0.0003
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.018 0.018
Echinococcus multilocularis lamin dm0 0.0029 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.011
Brugia malayi beta-lactamase family protein 0.0039 0.0119 0.0123
Echinococcus multilocularis microtubule associated protein 2 0.1509 0.7388 0.7388
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0046 0.0046
Entamoeba histolytica hypothetical protein 0.0043 0.0139 0.0748
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0517 0.2482 0.2573
Schistosoma mansoni cpg binding protein 0.0063 0.0235 0.0235
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0119 0.0119
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0085 0.0085
Onchocerca volvulus 0.0037 0.0109 0.0813
Onchocerca volvulus 0.0039 0.0119 0.0885
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0085 0.0088
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0071 0.0277 0.0174
Onchocerca volvulus 0.0029 0.007 0.0522
Brugia malayi steroid hormone receptor 0.0032 0.0085 0.0088
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0085 0.0085
Leishmania major hypothetical protein, conserved 0.0039 0.0119 0.0014
Onchocerca volvulus 0.0037 0.0105 0.0784
Echinococcus multilocularis cpg binding protein 0.0066 0.0253 0.0253
Brugia malayi Cathepsin L-like precursor 0.0025 0.0046 0.0047
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Schistosoma mansoni hypothetical protein 0.0105 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Echinococcus multilocularis cathepsin L 0.0019 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0085 0.0088
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0776 0.3762 0.6094
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0119 0.0764
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Echinococcus granulosus cathepsin L 0.0019 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0047
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0071 0.0277 0.0434
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0046 0.0046
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.018 0.0187
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0085 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0172 0.0172
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.018 0.0187
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0276 0.129 0.3213
Loa Loa (eye worm) hypothetical protein 0.0071 0.0277 0.0287
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0009 0.0009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0085 0.0085
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0276 0.129 0.3213
Onchocerca volvulus 0.0063 0.0235 0.1746
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0009 0.0009
Loa Loa (eye worm) fibroinase 0.0037 0.0105 0.0109
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0119 0.0119
Brugia malayi MH2 domain containing protein 0.0025 0.0046 0.0048
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0071 0.0277 0.026
Toxoplasma gondii pyruvate carboxylase 0.0776 0.3762 0.3696
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0172 0.0172
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0776 0.3762 0.3751
Brugia malayi Cathepsin L-like precursor 0.0037 0.0105 0.0109
Entamoeba histolytica hypothetical protein 0.0043 0.0139 0.0748
Brugia malayi Cathepsin L-like precursor 0.0025 0.0046 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0071 0.0277 0.0434
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0105 0.0105
Onchocerca volvulus 0.0037 0.0105 0.0784
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0172 0.0172
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0105 0.0105
Brugia malayi nuclear receptor RXR 0.0017 0.0009 0.0009
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0071 0.0277 0.0361
Echinococcus multilocularis smad 0.0025 0.0046 0.0046
Echinococcus granulosus dnaJ subfamily B 0.0894 0.4348 0.4348
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0134 0.0134
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0172 0.0178
Loa Loa (eye worm) transcription factor SMAD2 0.0362 0.1715 0.1778
Schistosoma mansoni lamin 0.0029 0.007 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0085 0.0088
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0085 0.0088
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0018 0.0018
Echinococcus granulosus lamin dm0 0.0029 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0112 0.0477 0.0477
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.1174 0.1217
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0276 0.129 0.3213
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0085 0.0088
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0134 0.0139
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0123
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0085 0.0085
Brugia malayi beta-lactamase family protein 0.0039 0.0119 0.0123
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0046 0.0048
Echinococcus granulosus cathepsin L cysteine protease 0.0019 0.0018 0.0018
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0776 0.3762 1
Onchocerca volvulus 0.0039 0.0119 0.0885
Loa Loa (eye worm) ctsf protein 0.0037 0.0105 0.0109
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0009 0.0009
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.2037 1 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.007 0.0073
Echinococcus multilocularis lamin 0.0029 0.007 0.007
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0085 0.0088
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0037 0.0105 0.0109
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0776 0.3762 1
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0071 0.0277 0.0423
Schistosoma mansoni cpg binding protein 0.0066 0.0253 0.0253
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0085 0.0085
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0009 0.0009
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0046 0.0048
Brugia malayi beta-lactamase 0.0039 0.0119 0.0123
Mycobacterium ulcerans hypothetical protein 0.0071 0.0277 0.0434
Onchocerca volvulus 0.0287 0.1346 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0085 0.0085
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Schistosoma mansoni Smad4 0.0025 0.0046 0.0046
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0071 0.0277 0.0423
Plasmodium vivax vivapain-2 0.0037 0.0105 0.0122
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0175 0.0792 0.126
Brugia malayi latrophilin 2 splice variant baaae 0.0112 0.0477 0.0495
Brugia malayi hypothetical protein 0.0043 0.0139 0.0144
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0276 0.129 0.129
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0276 0.129 0.3213
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0105 0.0143
Onchocerca volvulus 0.0039 0.0119 0.0885
Toxoplasma gondii ABC1 family protein 0.0039 0.0119 0.0014
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0071 0.0277 0.0174
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0046 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0172 0.0172
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0172 0.0172
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0071 0.0277 0.0434
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0085 0.0085
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0018 0.0018
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0009
Onchocerca volvulus 0.0037 0.0105 0.0784
Schistosoma mansoni pyruvate carboxylase 0.0776 0.3762 0.3762
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0175 0.0792 0.0792
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0071 0.0277 0.0174
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0172 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0071 0.0277 0.0423
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Brugia malayi intermediate filament protein 0.0029 0.007 0.0073
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0175 0.0792 0.1075
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0046 0.0046
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0276 0.129 0.3233
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0071 0.0277 0.0174
Plasmodium vivax SET domain protein, putative 0.0037 0.0109 0.0128
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0071 0.0277 0.0361
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0776 0.3762 1
Echinococcus multilocularis Smad4 0.0025 0.0046 0.0046
Brugia malayi nuclear hormone receptor 0.0032 0.0085 0.0088
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0776 0.3762 1
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0776 0.3762 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0043 0.0139 0.0139
Echinococcus granulosus cpg binding protein 0.0066 0.0253 0.0253
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0008 0.0008
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0235 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0071 0.0277 0.0434
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1474 0.7216 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0027 0.0027
Schistosoma mansoni aspartate carbamoyltransferase 0.0175 0.0792 0.0792
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0119 0.0764
Loa Loa (eye worm) beta-lactamase 0.0039 0.0119 0.0123
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0071 0.0277 0.026
Schistosoma mansoni smad1 5 8 and 0.0025 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0047
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0276 0.129 0.3213
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0276 0.129 0.3213
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0123
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0071 0.0277 0.0361
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0085 0.0088
Brugia malayi cathepsin L-like precursor 0.0025 0.0046 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0105 0.054
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0105 0.0661
Onchocerca volvulus 0.0037 0.0105 0.0784
Brugia malayi Cathepsin L-like cysteine proteinase 0.0025 0.0046 0.0047
Schistosoma mansoni smad 0.0025 0.0046 0.0046
Brugia malayi Cathepsin L-like precursor 0.0037 0.0105 0.0109
Schistosoma mansoni lamin 0.0029 0.007 0.007
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0276 0.129 0.207
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0127 0.0554 0.0874
Plasmodium vivax vivapain-2 0.0037 0.0105 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Echinococcus granulosus Smad4 0.0025 0.0046 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0175 0.0792 0.126
Toxoplasma gondii carbamoylphosphate synthetase 0.0175 0.0792 0.0694
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0109 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0119 0.0119
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.018 0.018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0135 0.059 0.059
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0276 0.129 0.3213
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0119 0.0165
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0109 0.0109
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0123
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0071 0.0277 0.0277
Schistosoma mansoni microtubule-associated protein tau 0.1509 0.7388 0.7388
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0017 0.0009 0.0009
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0105 0.0105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0085 0.0085
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0085 0.0088
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0119 0.0123
Brugia malayi ecdysteroid receptor 0.0032 0.0085 0.0088
Echinococcus multilocularis dnaJ subfamily B 0.0894 0.4348 0.4348
Plasmodium falciparum carbamoyl phosphate synthetase 0.0175 0.0792 0.1075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0085 0.0088
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0037 0.0105 0.0122
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0276 0.129 0.207
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0085 0.0088
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0018 0.0018
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0276 0.129 0.3213
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0085 0.0085
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0085 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0046 0.0172
Echinococcus granulosus cathepsin l cysteine peptidase 0.0037 0.0105 0.0105
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0085 0.0085
Brugia malayi Cathepsin L-like precursor 0.0037 0.0105 0.0109
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0119 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0134 0.0134
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0276 0.129 0.1197
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0109 0.0109
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0105 0.0105
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0109 0.0004
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0776 0.3762 0.3762
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.2037 1 1
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0119 0.0141
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0134 0.0139
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0071 0.0277 0.0361
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0123
Schistosoma mansoni hypothetical protein 0.0052 0.018 0.018
Onchocerca volvulus 0.0105 0.0446 0.3314
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0109 0.0109
Brugia malayi MH1 domain containing protein 0.0025 0.0046 0.0048
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0071 0.0277 0.026
Loa Loa (eye worm) hypothetical protein 0.0029 0.007 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0276 0.129 0.2905
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0071 0.0277 0.0423
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0085 0.0629
Brugia malayi Carboxyl transferase domain containing protein 0.1966 0.9647 1
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0085 0.0085
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0139 0.0139
Schistosoma mansoni hypothetical protein 0.0894 0.4348 0.4348
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0347 0.1643 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0085 0.0088
Onchocerca volvulus 0.0037 0.0105 0.0784
Echinococcus granulosus smad 0.0025 0.0046 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.014 0.0614 0.0598
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0153 0.0153
Brugia malayi Calcitonin receptor-like protein seb-1 0.0164 0.0733 0.076
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0776 0.3762 0.3762
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0085 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0119 0.0165
Leishmania major cathepsin L-like protease 0.014 0.0614 0.0514
Mycobacterium ulcerans pyruvate carboxylase 0.0776 0.3762 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0175 0.0792 0.1476
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0119 0.0764
Echinococcus multilocularis cysteine protease 0.0037 0.0105 0.0105
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0071 0.0277 0.0174
Chlamydia trachomatis biotin carboxylase 0.0705 0.3409 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0105 0.054
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0276 0.129 0.1197
Echinococcus multilocularis GPCR, family 2 0.0052 0.018 0.018
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0085 0.0085
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.012 0.0773
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0071 0.0277 0.0434
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0276 0.129 0.207
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0037 0.0105 0.0122
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0037 0.0109 0.0113
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0071 0.0277 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0105 0.0661
Onchocerca volvulus 0.0037 0.0105 0.0784
Schistosoma mansoni cpg binding protein 0.0066 0.0253 0.0253
Echinococcus granulosus GPCR family 2 0.0052 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0088
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0164 0.0733 0.076
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0085 0.0085
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0139 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0085 0.0088
Brugia malayi Pre-SET motif family protein 0.0037 0.0109 0.0113
Brugia malayi MH2 domain containing protein 0.0362 0.1715 0.1778
Trypanosoma cruzi cysteine peptidase, putative 0.014 0.0614 0.0971
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0085 0.0088
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0119 0.0764
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0252 0.1168 0.288
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0071 0.0277 0.0287
Schistosoma mansoni intermediate filament proteins 0.0029 0.007 0.007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0085 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0085 0.0088
Schistosoma mansoni smad1 5 8 and 0.0025 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0105 0.0661
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.018 0.018
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0071 0.0277 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0046 0.021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0085 0.0085
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0008 0.0008
Echinococcus multilocularis cysteine protease 0.0037 0.0105 0.0105
Schistosoma mansoni acetyl-CoA carboxylase 0.2037 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.