Detailed information for compound 954536

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 668.828 | Formula: C44H40N6O
  • H donors: 4 H acceptors: 1 LogP: 8.81 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: NC(=N)NCCNc1ccc(cc1c1ccccc1)C(=O)Nc1ccc(cc1)N(Cc1ccc2c(c1)cccc2)Cc1ccc2c(c1)cccc2
  • InChi: 1S/C44H40N6O/c45-44(46)48-25-24-47-42-23-18-38(28-41(42)35-10-2-1-3-11-35)43(51)49-39-19-21-40(22-20-39)50(29-31-14-16-33-8-4-6-12-36(33)26-31)30-32-15-17-34-9-5-7-13-37(34)27-32/h1-23,26-28,47H,24-25,29-30H2,(H,49,51)(H4,45,46,48)
  • InChiKey: LKOYIVKBBBEBSU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0152 0.0428 0.1987
Loa Loa (eye worm) hypothetical protein 0.0718 0.2152 1
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Schistosoma mansoni smad 0.0034 0.0066 0.0205
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Brugia malayi SET domain containing protein 0.0013 0.0002 0.0009
Echinococcus granulosus smad 0.0034 0.0066 0.0205
Giardia lamblia Fructose-bisphosphate aldolase 0.0884 0.2659 1
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0087 0.0307
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0009 0.0039
Onchocerca volvulus 0.0148 0.0416 0.1897
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Echinococcus multilocularis son of sevenless 1 0.0025 0.004 0.0038
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0242 0.0241
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.0409 0.0407
Plasmodium vivax glutathione reductase, putative 0.0048 0.0108 0.2461
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.0409 0.082
Echinococcus multilocularis expressed protein 0.0033 0.0063 0.0061
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0165 0.0164
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0035 0.0071 0.0222
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0015 0.001 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Brugia malayi hypothetical protein 0.0148 0.0416 0.1931
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0015 0.001 0.0009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0115
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.005 0.0117 0.2678
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0169 0.0615
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0024 0.007
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0098 0.0261 0.1213
Schistosoma mansoni hypothetical protein 0.0036 0.0073 0.023
Schistosoma mansoni chromobox protein 0.0068 0.0169 0.0536
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0409 0.1519
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0097 0.0453
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0013 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Echinococcus multilocularis muscleblind protein 0.0152 0.0428 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0242 0.0771
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0015 0.001 0.0028
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.0409 0.082
Loa Loa (eye worm) DIX domain-containing protein 0.0035 0.0071 0.0327
Trypanosoma brucei protein kinase A regulatory subunit 0.0015 0.001 0.018
Leishmania major hypothetical protein, conserved 0.0146 0.0409 1
Echinococcus granulosus regulator of G protein signaling 7 0.0035 0.0071 0.0222
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.001 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.001 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0024 0.011
Echinococcus multilocularis ras GTP exchange factor 0.0025 0.004 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0024 0.0108
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0015 0.001 0.018
Loa Loa (eye worm) hypothetical protein 0.0152 0.0428 0.1987
Echinococcus multilocularis Protein son of sevenless 0.0025 0.004 0.0038
Schistosoma mansoni hypothetical protein 0.1036 0.3124 1
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0101 0.036
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0061 0.1266
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0025 0.004 0.0129
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0049 0.0981
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0117 0.2678
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.001 0.0009
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0013 0.0062
Plasmodium falciparum thioredoxin reductase 0.0017 0.0013 0.027
Mycobacterium tuberculosis Probable reductase 0.0109 0.0294 0.0585
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0024 0.0069
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0024 0.011
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.001 0.0028
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.065 0.0648
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0294 0.0585
Schistosoma mansoni hypothetical protein 0.0211 0.0608 0.1941
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0024 0.0022
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0019
Brugia malayi nuclear receptor NHR-88 0.002 0.0024 0.011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0053 0.0051
Brugia malayi nuclear hormone receptor 0.002 0.0024 0.011
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0242 0.1089
Trichomonas vaginalis rotamase, putative 0.0033 0.0063 0.0216
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0049 0.1144
Loa Loa (eye worm) AGC/PKG protein kinase 0.0016 0.0011 0.005
Brugia malayi hypothetical protein 0.0035 0.0071 0.0329
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0024 0.0022
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0098 0.0261 0.026
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0021 0.0057
Echinococcus multilocularis geminin 0.1036 0.3124 0.3122
Brugia malayi Isocitrate dehydrogenase 0.005 0.0117 0.0543
Schistosoma mansoni hypothetical protein 0.1036 0.3124 1
Brugia malayi N-terminal motif family protein 0.0025 0.004 0.0185
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0015 0.001 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0409 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.065 0.2076
Onchocerca volvulus 0.0146 0.0409 0.1865
Toxoplasma gondii hypothetical protein 0.0035 0.0071 0.1518
Schistosoma mansoni smad1 5 8 and 0.0034 0.0066 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus granulosus intermediate filament protein 0.0026 0.0044 0.0134
Schistosoma mansoni smad 0.0015 0.0009 0.0023
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Echinococcus multilocularis expressed conserved protein 0.0016 0.0011 0.001
Brugia malayi RasGEF domain containing protein 0.0025 0.004 0.0185
Echinococcus multilocularis snurportin 1 0.0302 0.0885 0.0883
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0024 0.011
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0194
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0039 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0534 0.1991
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0081 0.1775
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0409 0.1519
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0718 0.2152 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Brugia malayi MH2 domain containing protein 0.0493 0.1468 0.6821
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0053 0.0165
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Brugia malayi MH1 domain containing protein 0.0034 0.0066 0.0305
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.065 0.2076
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Brugia malayi chromobox protein homolog 3 0.0038 0.0078 0.0365
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0024 0.0022
Loa Loa (eye worm) RasGEF domain-containing protein 0.0025 0.004 0.0183
Echinococcus granulosus segment polarity protein dishevelled 0.0035 0.0071 0.0222
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0062
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0013 0.0006
Schistosoma mansoni Smad4 0.0034 0.0066 0.0205
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0066 0.0064
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0015 0.001 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0024 0.0108
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0024 0.0022
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0053 0.0125 0.0578
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0024 0.0022
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.0028
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0884 0.2659 1
Leishmania major protein kinase, putative 0.0016 0.0011 0.0023
Echinococcus granulosus voltage gated potassium channel 0.0015 0.001 0.0028
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Echinococcus granulosus GPCR family 2 0.0098 0.0261 0.0832
Onchocerca volvulus 0.002 0.0024 0.0069
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0048 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0024 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Brugia malayi MH2 domain containing protein 0.0015 0.0009 0.0041
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0432 0.128 0.2615
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0013 0.0078
Toxoplasma gondii exonuclease III APE 0.0039 0.0081 0.1775
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0081 0.0146
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0013 0.0078
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0015 0.001 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Loa Loa (eye worm) RasGEF domain-containing protein 0.0025 0.004 0.0183
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.009
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0025 0.004 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0101 0.036
Brugia malayi Calcitonin receptor-like protein seb-1 0.0309 0.0906 0.421
Giardia lamblia DINP protein human, muc B family 0.0019 0.0021 0.004
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0009 0.0007
Trichomonas vaginalis set domain proteins, putative 0.023 0.0665 0.2484
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0007 0.0005
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0061 0.1423
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0044 0.0201
Brugia malayi hypothetical protein 0.0025 0.0039 0.018
Brugia malayi beta-lactamase 0.0146 0.0409 0.1899
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0053 0.0125 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0242 0.0771
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0061 0.1266
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Trypanosoma cruzi hypothetical protein 0.0025 0.004 0.0742
Schistosoma mansoni dishevelled 0.0035 0.0071 0.0222
Trypanosoma brucei isocitrate dehydrogenase, putative 0.005 0.0117 0.281
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0098 0.0261 0.0832
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0239 0.0692 0.3214
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0063 0.0216
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.1608 0.4865 1
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0256
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Onchocerca volvulus 0.0026 0.0044 0.0162
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0081 0.6174
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0108 0.0501
Echinococcus multilocularis chromobox protein 1 0.0068 0.0169 0.0167
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.005 0.0117 0.0115
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0066 0.0205
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.005 0.0117 0.0542
Schistosoma mansoni lamin 0.0026 0.0044 0.0134
Brugia malayi ecdysteroid receptor 0.002 0.0024 0.011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0078 0.0325
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0015 0.001 0.0048
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.0201
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.0011 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0011 0.0031
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0002 0.0001
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0108 0.0107
Onchocerca volvulus Huntingtin homolog 0.0239 0.0692 0.3187
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.0183
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0015 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0046
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0097 0.2187
Leishmania major hypothetical protein, conserved 0.0025 0.0039 0.0715
Mycobacterium leprae Probable lipase LipE 0.0146 0.0409 0.082
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0066 0.0205
Schistosoma mansoni rotamase 0.0033 0.0063 0.0197
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0035 0.0071 0.0329
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0081 0.1923
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0046
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.0409 0.082
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.005 0.0117 0.0369
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0024 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0024 0.0108
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0081 0.0254
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0053 0.0125 0.3003
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0021 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0024 0.0022
Echinococcus granulosus cGMP dependent protein kinase 0.0016 0.0011 0.0031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0024 0.007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0024 0.007
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.001 0.0028
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0009 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0024 0.011
Schistosoma mansoni nuclear hormone receptor 0.002 0.0024 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0081 0.1775
Schistosoma mansoni ap endonuclease 0.0039 0.0081 0.0254
Echinococcus granulosus cpg binding protein 0.003 0.0053 0.0166
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0009 0.0023
Brugia malayi Smad1 0.0034 0.0066 0.0305
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0015 0.001 0.0028
Leishmania major protein kinase, putative 0.0016 0.0011 0.0023
Echinococcus multilocularis Smad4 0.0034 0.0066 0.0064
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0021 0.0062
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0053 0.0165
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0057 0.1184
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0309 0.0906 0.421
Schistosoma mansoni lamin 0.0026 0.0044 0.0134
Brugia malayi regulator of G-protein signaling egl-10 0.0035 0.0071 0.0329
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0024 0.011
Plasmodium falciparum glutathione reductase 0.0017 0.0013 0.027
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0053 0.0125 0.2875
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0024 0.0036 0.011
Brugia malayi N-terminal motif family protein 0.0025 0.004 0.0185
Mycobacterium ulcerans beta-lactamase 0.0146 0.0409 0.082
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0409 1
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0409 0.1519
Loa Loa (eye worm) beta-lactamase 0.0146 0.0409 0.1897
Loa Loa (eye worm) hypothetical protein 0.0211 0.0608 0.2822
Onchocerca volvulus 0.003 0.0054 0.0208
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0021 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0024 0.0022
Trypanosoma brucei cAMP response protein 1, putative 0.0015 0.001 0.018
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0061 0.0151
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0247
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0063 0.0293
Brugia malayi hypothetical protein 0.0239 0.0692 0.3215
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0024 0.007
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0013 0.0256
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.001 0.0028
Plasmodium vivax importin-beta 2, putative 0.0028 0.0049 0.0981
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0024 0.007
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.1608 0.4865 1
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0039 0.0715
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0169 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0147
Brugia malayi hypothetical protein 0.0016 0.0012 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0053 0.0165
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0057 0.1184
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.001 0.0028
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.005 0.0117 0.9315
Schistosoma mansoni z-protein (S1r protein) 0.0035 0.0071 0.0222
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.0409 0.1304
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0081 0.0228
Brugia malayi glutathione reductase 0.0048 0.0108 0.0503
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0021 0.0022
Echinococcus granulosus ras GTP exchange factor 0.0025 0.004 0.0122
Loa Loa (eye worm) transcription factor SMAD2 0.0493 0.1468 0.682
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0081 0.0376
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0015 0.001 0.0017
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0117 0.2678
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0033 0.0103
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0025 0.004 0.0122
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.0028
Onchocerca volvulus 0.0146 0.0409 0.1865
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0024 0.007
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0053 0.0125 0.2875
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0013 0.0006
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0432 0.128 0.2615
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Schistosoma mansoni dep domain containing protein 0.0035 0.0071 0.0222
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0024 0.0069
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0934 0.281 0.5766
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0053 0.0125 0.0432
Brugia malayi CHD4 protein 0.0013 0.0002 0.0007
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0097 0.2328
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0024 0.007
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0015 0.001 0.0028
Trichomonas vaginalis esterase, putative 0.0146 0.0409 0.1519
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0024 0.011
Brugia malayi RNA, U transporter 1 0.0081 0.0209 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Echinococcus multilocularis isocitrate dehydrogenase 0.005 0.0117 0.0115
Brugia malayi MH2 domain containing protein 0.0034 0.0066 0.0305
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi hypothetical protein 0.0036 0.0073 0.0341
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Brugia malayi latrophilin 2 splice variant baaae 0.0211 0.0608 0.2824
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0007
Leishmania major trypanothione reductase 0.0048 0.0108 0.2461
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0015 0.001 0.0046
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0053 0.0125 0.0395
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.0505 0.2314
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0428 0.0426
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0021 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Trichomonas vaginalis ras GTP exchange factor, putative 0.0025 0.004 0.0129
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0013 1
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0409 0.1519
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Brugia malayi beta-lactamase family protein 0.0146 0.0409 0.1899
Mycobacterium leprae conserved hypothetical protein 0.0146 0.0409 0.082
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0331 0.0661
Schistosoma mansoni cpg binding protein 0.003 0.0053 0.0166
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0327
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.0409 0.082
Schistosoma mansoni coup transcription factor 0.002 0.0024 0.007
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.001 0.0048
Brugia malayi isocitrate dehydrogenase 0.005 0.0117 0.0543
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0053 0.0125 0.2875
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0081 0.0079
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0169 0.0783
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0103
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0081 0.0146
Onchocerca volvulus 0.0146 0.0409 0.1865
Echinococcus granulosus snurportin 1 0.0302 0.0885 0.2829
Loa Loa (eye worm) nuclear factor I 0.0019 0.002 0.009
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.0409 0.082
Mycobacterium tuberculosis Conserved protein 0.0146 0.0409 0.082
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0117 0.2678
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0011 0.0031
Echinococcus granulosus muscleblind protein 0.0152 0.0428 0.1366
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.0009
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0081 0.1775
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.065 0.2076
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.0885 0.411
Mycobacterium ulcerans hypothetical protein 0.0146 0.0409 0.082
Schistosoma mansoni importin beta-1 0.0028 0.0049 0.0153
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0108 0.2461
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.0183
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0035 0.0071 0.0327
Onchocerca volvulus 0.023 0.0665 0.306
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.001 0.0028
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0053 0.0051
Onchocerca volvulus 0.0028 0.0049 0.0185
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0073 0.023
Loa Loa (eye worm) hypothetical protein 0.0148 0.0416 0.1929
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0039 0.2489
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0117 0.2678
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0078 0.0274
Schistosoma mansoni ap endonuclease 0.0039 0.0081 0.0254
Echinococcus granulosus expressed protein 0.0033 0.0063 0.0197
Brugia malayi MH1 domain containing protein 0.0019 0.002 0.0092
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0015 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0363
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0024 0.011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.001 0.0028
Trypanosoma brucei trypanothione reductase 0.0048 0.0108 0.2597
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Schistosoma mansoni ras GTP exchange factor 0.0025 0.004 0.0122
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0035 0.0071 0.0069
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0242 0.5823
Echinococcus granulosus chromobox protein 1 0.0068 0.0169 0.0536
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0039 0.0715
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0066 0.0303
Brugia malayi Thioredoxin reductase 0.0048 0.0108 0.0503
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0443
Echinococcus multilocularis lamin dm0 0.0026 0.0044 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0049 0.0224
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Schistosoma mansoni DNA polymerase eta 0.0044 0.0097 0.0307
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0044 0.0201
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0165 0.0164
Echinococcus granulosus Pleckstrin G protein interacting region 0.0035 0.0071 0.0222
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0021 0.0019
Leishmania major DNA polymerase eta, putative 0.0044 0.0097 0.2187
Brugia malayi CXXC zinc finger family protein 0.0028 0.0049 0.0226
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.0409 0.082
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0024 0.007
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0066 0.0303
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Loa Loa (eye worm) hypothetical protein 0.0309 0.0906 0.4209
Onchocerca volvulus 0.0026 0.0044 0.0162
Entamoeba histolytica hypothetical protein 0.0025 0.004 0.0072
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.0009
Giardia lamblia Kinase, PLK 0.0092 0.0242 0.0876
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.001 0.0009
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.001 0.0046
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0242 0.5823
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0021 0.0062
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0073 0.023
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0013 0.0078
Echinococcus multilocularis segment polarity protein dishevelled 0.0035 0.0071 0.0069
Schistosoma mansoni intermediate filament proteins 0.0026 0.0044 0.0134
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0053 0.0125 0.0394
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0108 0.0202
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0015 0.001 0.0028
Echinococcus multilocularis lamin 0.0026 0.0044 0.0042
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0038
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.0409 0.1899
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0245
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0012
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.001 0.0046
Brugia malayi Pre-SET motif family protein 0.003 0.0053 0.0247
Echinococcus multilocularis cpg binding protein 0.003 0.0053 0.0052
Brugia malayi hypothetical protein 0.0035 0.0071 0.0329
Plasmodium falciparum cGMP-dependent protein kinase 0.0016 0.0011 0.0079
Brugia malayi MH1 domain containing protein 0.0034 0.0066 0.0305
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0016 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0025 0.004 0.0129
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0024 0.007
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0081 0.1775
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0242 0.5823
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0432 0.128 0.2615
Trypanosoma brucei cAMP binding protein, putative 0.0015 0.001 0.018
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0165 0.0524
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0015 0.001 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0011 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0409 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0147
Brugia malayi DIX domain containing protein 0.0035 0.0071 0.0329
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Echinococcus granulosus lamin 0.0026 0.0044 0.0134
Leishmania major DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Leishmania major DNA polymerase eta, putative 0.0031 0.0057 0.1184
Brugia malayi MH2 domain containing protein 0.0034 0.0066 0.0305
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0015 0.001 0.0017
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0024 0.0108
Echinococcus granulosus son of sevenless 1 0.0025 0.004 0.0122
Echinococcus granulosus importin subunit beta 1 0.0028 0.0049 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0024 0.011
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0025 0.004 0.0122
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0021 0.0268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0035 0.0071 0.0069
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0331 0.0661
Echinococcus multilocularis smad 0.0034 0.0066 0.0064
Brugia malayi RasGEF domain containing protein 0.0025 0.004 0.0185
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0013 0.0029
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0081 0.0267
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.0261 0.0832
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0024 0.007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0024 0.011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0053 0.0125 0.0394
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0013 0.0078
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0053 0.0125 0.058
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0294 0.0585
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0021 0.0097
Toxoplasma gondii thioredoxin reductase 0.0048 0.0108 0.2461
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.0011 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0443
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0066 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.001 0.0028
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0024 0.007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0073 0.0072
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0009 0.0007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.0261 0.1215
Brugia malayi Heterochromatin protein 1 0.0068 0.0169 0.0785
Schistosoma mansoni kinase 0.0047 0.0105 0.0331
Echinococcus granulosus Smad4 0.0034 0.0066 0.0205
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0013 0.0078
Echinococcus granulosus segment polarity protein dishevelled 0.0035 0.0071 0.0222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0053 0.0165
Loa Loa (eye worm) glutathione reductase 0.0048 0.0108 0.0501
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.0261 0.026
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0024 0.011
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0006 0.0027
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0039
Brugia malayi Muscleblind-like protein 0.0152 0.0428 0.1989
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0025 0.004 0.0122
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.058 0.2692
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0294 0.0585
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0025 0.004 0.0122
Schistosoma mansoni thyroid hormone receptor 0.002 0.0024 0.007
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0015 0.001 0.018
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0087 0.0273
Plasmodium falciparum thioredoxin reductase 0.0048 0.0108 0.8559
Loa Loa (eye worm) MH2 domain-containing protein 0.0493 0.1468 0.682
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Onchocerca volvulus 0.0025 0.004 0.0145
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0016 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0227
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0025 0.004 0.0145
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0035 0.0071 0.0289
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0271 0.0789 0.3665
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0294 0.0585
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0024 0.0022
Echinococcus granulosus dna polymerase eta 0.0044 0.0097 0.0307
Echinococcus multilocularis GPCR, family 2 0.0098 0.0261 0.026
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0225 0.065 0.3017
Echinococcus granulosus dna polymerase kappa 0.0019 0.0021 0.0062
Brugia malayi Latrophilin receptor protein 2 0.0098 0.0261 0.1215
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.0178
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0053 0.0125 0.0395
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0534 0.1991
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0013 0.027
Schistosoma mansoni smad1 5 8 and 0.0034 0.0066 0.0205
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0087 0.0307
Loa Loa (eye worm) hypothetical protein 0.0044 0.0097 0.0451
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0013 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0128 0.2964
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0165 0.0524
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0081 1
Trypanosoma brucei polo-like protein kinase 0.0092 0.0242 0.5898
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0081 0.0284
Trypanosoma brucei Flagellar Member 6 0.0015 0.001 0.018
Treponema pallidum NADH oxidase 0.0017 0.0013 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0024 0.011
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.0409 0.082
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0024 0.007
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0117 0.281
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0006 0.0029
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0044 0.0202
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0015 0.001 0.0028
Echinococcus granulosus geminin 0.1036 0.3124 1
Loa Loa (eye worm) Smad1 0.0034 0.0066 0.0303
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0024 0.007
Schistosoma mansoni dishevelled 0.0035 0.0071 0.0222
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0409 0.1304
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0015 0.001 0.0028
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0033 0.0571
Echinococcus granulosus regulator of G protein signaling 7 0.0035 0.0071 0.0222
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0294 0.0585
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0013 0.0256
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0015 0.001 0.0048
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0061 0.1266
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.065 0.0648
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0225 0.065 0.3019
Onchocerca volvulus 0.0015 0.001 0.0007
Mycobacterium tuberculosis Conserved protein 0.0146 0.0409 0.082
Echinococcus granulosus patatin phospholipase domain containing protein 0.0015 0.001 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0015 0.001 0.0028
Brugia malayi MH1 domain containing protein 0.0019 0.002 0.0092
Entamoeba histolytica hypothetical protein 0.0023 0.0033 0.0046
Onchocerca volvulus 0.0015 0.001 0.0007
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0242 0.1124
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0015 0.001 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.065 0.2076
Loa Loa (eye worm) RasGEF domain-containing protein 0.0025 0.004 0.0183
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.0409 0.082
Schistosoma mansoni Smad4 0.0015 0.0009 0.0023
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0049 0.0048
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0021 0.0022
Mycobacterium ulcerans lipase LipD 0.0146 0.0409 0.082
Schistosoma mansoni smad1 5 8 and 0.0034 0.0066 0.0205
Mycobacterium tuberculosis Conserved hypothetical protein 0.0053 0.0125 0.0236
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0327
Schistosoma mansoni thyroid hormone receptor 0.002 0.0024 0.007
Brugia malayi steroid hormone receptor 0.002 0.0024 0.011
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0025 0.004 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0039 0.0715
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0024 0.007
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0409 0.1519
Echinococcus granulosus lamin dm0 0.0026 0.0044 0.0134
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0024 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.065 0.2076
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.0009
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0081 0.0374
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0256
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0309 0.0906 0.4209
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.0053 0.0125 0.0236
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.1608 0.4865 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0115
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0087 0.0366
Loa Loa (eye worm) hypothetical protein 0.0239 0.0692 0.3214
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0081 0.0267
Schistosoma mansoni hypothetical protein 0.0302 0.0885 0.2829
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus multilocularis musashi 0.0026 0.0044 0.0042
Onchocerca volvulus 0.0035 0.0071 0.0289
Brugia malayi Pre-SET motif family protein 0.0202 0.058 0.2694
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.001 0.0009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.0261 0.1213
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0327
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0049 0.1144
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0025 0.004 0.0122
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.0053 0.0125 0.0236
Toxoplasma gondii ABC1 family protein 0.0146 0.0409 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.001 0.0048
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Schistosoma mansoni cpg binding protein 0.003 0.0053 0.0166
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0015 0.001 0.0028
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0013 0.027
Plasmodium falciparum importin beta, putative 0.0028 0.0049 0.3414
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0053 0.0125 0.2875
Trypanosoma brucei unspecified product 0.0019 0.0021 0.0443
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0024 0.007
Onchocerca volvulus Huntingtin homolog 0.0239 0.0692 0.3187
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0053 0.0125 0.0449
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0443
Schistosoma mansoni cpg binding protein 0.0028 0.0049 0.015
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0165 0.0524
Mycobacterium tuberculosis Conserved protein 0.0146 0.0409 0.082
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0024 0.011
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.0409 0.082
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.005 0.0117 0.2678
Leishmania major importin beta-1 subunit, putative 0.0023 0.0033 0.0571
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0331 0.0661
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0013 0.0029
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.001 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0108 0.2461
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0053 0.0125 0.2875
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0015 0.001 0.0009
Brugia malayi beta-lactamase family protein 0.0146 0.0409 0.1899
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Echinococcus multilocularis dna polymerase eta 0.0044 0.0097 0.0096
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.0409 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0165 0.0164
Schistosoma mansoni regulator of G protein signaling 0.0035 0.0071 0.0222
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0081 0.0284
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0024 0.0108
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0066 0.0205
Echinococcus granulosus Protein son of sevenless 0.0025 0.004 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0078 0.0274
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0331 0.0661
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0024 0.0108
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0271 0.0789 0.3664
Schistosoma mansoni Smad4 0.0015 0.0009 0.0023
Echinococcus multilocularis segment polarity protein dishevelled 0.0035 0.0071 0.0069
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0409 0.1304
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0024 0.011
Brugia malayi RasGEF domain containing protein 0.0025 0.004 0.0185
Brugia malayi Egg laying defective protein 4 0.0016 0.0011 0.0052
Onchocerca volvulus 0.0041 0.0087 0.0364
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0015 0.001 0.0028
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0009 0.0039
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.001 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Brugia malayi Importin beta-1 subunit 0.0028 0.0049 0.0229
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.005 0.0117 0.022
Trypanosoma cruzi hypothetical protein 0.0025 0.004 0.0742
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0024 0.011
Echinococcus granulosus FTZ F1 alpha 0.002 0.0024 0.007
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0242 0.0839
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0035 0.0071 0.0329
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0369
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0053 0.0125 0.0123
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0013 0.0078
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Plasmodium falciparum glutathione reductase 0.0048 0.0108 0.8559
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.0409 0.1897
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.001 0.0009
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0063 0.0291
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0242 0.1125
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0025 0.004 0.0742
Brugia malayi N-terminal motif family protein 0.0718 0.2152 1
Trichomonas vaginalis ras GTP exchange factor, putative 0.0025 0.004 0.0129
Echinococcus granulosus chromobox protein 1 0.0068 0.0169 0.0536
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0025 0.004 0.0038
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0294 0.0585
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0108 0.0342
Plasmodium vivax SET domain protein, putative 0.003 0.0053 0.1074
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0009 0.0023
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0053 0.1074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0024 0.0069
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0148 0.0468
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0039 0.0883
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0002 0.0005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0013 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0024 0.0108
Treponema pallidum fructose-bisphosphate aldolase 0.0884 0.2659 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0039 0.2489
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0061 0.1266
Trichomonas vaginalis rotamase, putative 0.0032 0.0061 0.0207
Brugia malayi intermediate filament protein 0.0026 0.0044 0.0202
Echinococcus multilocularis chromobox protein 1 0.0068 0.0169 0.0167
Schistosoma mansoni chromobox protein 0.0068 0.0169 0.0536
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0021 0.0057
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.0011 0.001
Echinococcus multilocularis regulator of G protein signaling 7 0.0035 0.0071 0.0069

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 23 uM Inhibition of Akt1 by fluorescence polarization assay ChEMBL. 19179081

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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