Detailed information for compound 956589

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 668.828 | Formula: C44H40N6O
  • H donors: 4 H acceptors: 1 LogP: 8.81 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: NC(=N)NCCNc1ccc(cc1c1ccccc1)C(=O)Nc1ccc(cc1)N(Cc1cccc2c1cccc2)Cc1cccc2c1cccc2
  • InChi: 1S/C44H40N6O/c45-44(46)48-27-26-47-42-25-20-34(28-41(42)33-10-2-1-3-11-33)43(51)49-37-21-23-38(24-22-37)50(29-35-16-8-14-31-12-4-6-18-39(31)35)30-36-17-9-15-32-13-5-7-19-40(32)36/h1-25,28,47H,26-27,29-30H2,(H,49,51)(H4,45,46,48)
  • InChiKey: OGRRBBPSFUIYFS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0044 0.0097 0.0451
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0087 0.0307
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Schistosoma mansoni smad1 5 8 and 0.0034 0.0066 0.0205
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0013 0.027
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0534 0.1991
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0053 0.0125 0.0395
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.0178
Echinococcus granulosus dna polymerase kappa 0.0019 0.0021 0.0062
Brugia malayi Latrophilin receptor protein 2 0.0098 0.0261 0.1215
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0225 0.065 0.3017
Echinococcus granulosus dna polymerase eta 0.0044 0.0097 0.0307
Echinococcus multilocularis GPCR, family 2 0.0098 0.0261 0.026
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0024 0.0022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0294 0.0585
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0025 0.004 0.0145
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0271 0.0789 0.3665
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0035 0.0071 0.0289
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0227
Onchocerca volvulus 0.0025 0.004 0.0145
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0016 0.0011 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Loa Loa (eye worm) MH2 domain-containing protein 0.0493 0.1468 0.682
Plasmodium falciparum thioredoxin reductase 0.0048 0.0108 0.8559
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0087 0.0273
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0015 0.001 0.018
Schistosoma mansoni thyroid hormone receptor 0.002 0.0024 0.007
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0025 0.004 0.0122
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0294 0.0585
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.058 0.2692
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0025 0.004 0.0122
Brugia malayi Muscleblind-like protein 0.0152 0.0428 0.1989
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0039
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0013 0.0078
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0006 0.0027
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.0261 0.026
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0024 0.011
Loa Loa (eye worm) glutathione reductase 0.0048 0.0108 0.0501
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0053 0.0165
Echinococcus granulosus segment polarity protein dishevelled 0.0035 0.0071 0.0222
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0013 0.0078
Echinococcus granulosus Smad4 0.0034 0.0066 0.0205
Schistosoma mansoni kinase 0.0047 0.0105 0.0331
Brugia malayi Heterochromatin protein 1 0.0068 0.0169 0.0785
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0009 0.0007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.0261 0.1215
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0024 0.007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0073 0.0072
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.001 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0066 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0443
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.0011 0.001
Toxoplasma gondii thioredoxin reductase 0.0048 0.0108 0.2461
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0021 0.0097
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0294 0.0585
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0053 0.0125 0.058
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0053 0.0125 0.0394
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0024 0.011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0024 0.007
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0028
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0081 0.0267
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.0261 0.0832
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0013 0.0029
Brugia malayi RasGEF domain containing protein 0.0025 0.004 0.0185
Echinococcus multilocularis regulator of G protein signaling 7 0.0035 0.0071 0.0069
Echinococcus multilocularis smad 0.0034 0.0066 0.0064
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0331 0.0661
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0021 0.0268
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0025 0.004 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0024 0.011
Echinococcus granulosus importin subunit beta 1 0.0028 0.0049 0.0153
Echinococcus granulosus son of sevenless 1 0.0025 0.004 0.0122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0024 0.0108
Leishmania major DNA polymerase eta, putative 0.0031 0.0057 0.1184
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0115
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0015 0.001 0.0017
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Brugia malayi MH2 domain containing protein 0.0034 0.0066 0.0305
Leishmania major DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Echinococcus granulosus lamin 0.0026 0.0044 0.0134
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Brugia malayi DIX domain containing protein 0.0035 0.0071 0.0329
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0147
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0015 0.001 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0011 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0409 1
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0165 0.0524
Trypanosoma brucei cAMP binding protein, putative 0.0015 0.001 0.018
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0432 0.128 0.2615
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0242 0.5823
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0024 0.007
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0025 0.004 0.0129
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0081 0.1775
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Brugia malayi MH1 domain containing protein 0.0034 0.0066 0.0305
Plasmodium falciparum cGMP-dependent protein kinase 0.0016 0.0011 0.0079
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0016 0.0039
Brugia malayi Pre-SET motif family protein 0.003 0.0053 0.0247
Brugia malayi hypothetical protein 0.0035 0.0071 0.0329
Echinococcus multilocularis cpg binding protein 0.003 0.0053 0.0052
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.001 0.0046
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0245
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.0409 0.1899
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0038
Echinococcus multilocularis lamin 0.0026 0.0044 0.0042
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0015 0.001 0.0028
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0108 0.0202
Schistosoma mansoni intermediate filament proteins 0.0026 0.0044 0.0134
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0053 0.0125 0.0394
Echinococcus multilocularis segment polarity protein dishevelled 0.0035 0.0071 0.0069
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0013 0.0078
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0073 0.023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0021 0.0062
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0242 0.5823
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.001 0.0046
Giardia lamblia Kinase, PLK 0.0092 0.0242 0.0876
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.001 0.0009
Entamoeba histolytica hypothetical protein 0.0025 0.004 0.0072
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.0009
Onchocerca volvulus 0.0026 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0309 0.0906 0.4209
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0066 0.0303
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0024 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Brugia malayi CXXC zinc finger family protein 0.0028 0.0049 0.0226
Leishmania major DNA polymerase eta, putative 0.0044 0.0097 0.2187
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.0409 0.082
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0021 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Echinococcus granulosus Pleckstrin G protein interacting region 0.0035 0.0071 0.0222
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0165 0.0164
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0044 0.0201
Schistosoma mansoni DNA polymerase eta 0.0044 0.0097 0.0307
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0049 0.0224
Echinococcus multilocularis lamin dm0 0.0026 0.0044 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0443
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0039 0.0715
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0066 0.0303
Brugia malayi Thioredoxin reductase 0.0048 0.0108 0.0503
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Echinococcus granulosus chromobox protein 1 0.0068 0.0169 0.0536
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0035 0.0071 0.0069
Trypanosoma brucei trypanothione reductase 0.0048 0.0108 0.2597
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0242 0.5823
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.001 0.0028
Schistosoma mansoni ras GTP exchange factor 0.0025 0.004 0.0122
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0363
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0015 0.001 0.0028
Brugia malayi MH1 domain containing protein 0.0019 0.002 0.0092
Echinococcus granulosus expressed protein 0.0033 0.0063 0.0197
Schistosoma mansoni ap endonuclease 0.0039 0.0081 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0078 0.0274
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0117 0.2678
Loa Loa (eye worm) hypothetical protein 0.0148 0.0416 0.1929
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0073 0.023
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0039 0.2489
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0053 0.0051
Onchocerca volvulus 0.0028 0.0049 0.0185
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.001 0.0028
Onchocerca volvulus 0.023 0.0665 0.306
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0035 0.0071 0.0327
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.0183
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0024 0.007
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0108 0.2461
Schistosoma mansoni importin beta-1 0.0028 0.0049 0.0153
Mycobacterium ulcerans hypothetical protein 0.0146 0.0409 0.082
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.0885 0.411
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.065 0.2076
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0081 0.1775
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Echinococcus granulosus muscleblind protein 0.0152 0.0428 0.1366
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0011 0.0031
Mycobacterium tuberculosis Conserved protein 0.0146 0.0409 0.082
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0117 0.2678
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.0409 0.082
Echinococcus granulosus snurportin 1 0.0302 0.0885 0.2829
Loa Loa (eye worm) nuclear factor I 0.0019 0.002 0.009
Onchocerca volvulus 0.0146 0.0409 0.1865
Echinococcus multilocularis regulator of G protein signaling 7 0.0035 0.0071 0.0069
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0016 0.0011 0.001
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0021 0.0057
Schistosoma mansoni chromobox protein 0.0068 0.0169 0.0536
Echinococcus multilocularis chromobox protein 1 0.0068 0.0169 0.0167
Brugia malayi intermediate filament protein 0.0026 0.0044 0.0202
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0061 0.1266
Trichomonas vaginalis rotamase, putative 0.0032 0.0061 0.0207
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0039 0.2489
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0024 0.0108
Treponema pallidum fructose-bisphosphate aldolase 0.0884 0.2659 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0013 0.0078
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0039 0.0883
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0148 0.0468
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0024 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0053 0.1074
Plasmodium vivax SET domain protein, putative 0.003 0.0053 0.1074
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0009 0.0023
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0108 0.0342
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0025 0.004 0.0038
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0294 0.0585
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Trichomonas vaginalis ras GTP exchange factor, putative 0.0025 0.004 0.0129
Echinococcus granulosus chromobox protein 1 0.0068 0.0169 0.0536
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0063 0.0291
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0242 0.1125
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0025 0.004 0.0742
Brugia malayi N-terminal motif family protein 0.0718 0.2152 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.001 0.0009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.0409 0.1897
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0013 0.0078
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0369
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Plasmodium falciparum glutathione reductase 0.0048 0.0108 0.8559
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0035 0.0071 0.0329
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0053 0.0125 0.0123
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0242 0.0839
Echinococcus granulosus FTZ F1 alpha 0.002 0.0024 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0024 0.011
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.005 0.0117 0.022
Trypanosoma cruzi hypothetical protein 0.0025 0.004 0.0742
Brugia malayi Importin beta-1 subunit 0.0028 0.0049 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.001 0.0028
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0009 0.0039
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0015 0.001 0.0028
Onchocerca volvulus 0.0041 0.0087 0.0364
Brugia malayi Egg laying defective protein 4 0.0016 0.0011 0.0052
Brugia malayi RasGEF domain containing protein 0.0025 0.004 0.0185
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0024 0.011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0409 0.1304
Echinococcus multilocularis segment polarity protein dishevelled 0.0035 0.0071 0.0069
Schistosoma mansoni Smad4 0.0015 0.0009 0.0023
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0271 0.0789 0.3664
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0024 0.0108
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0331 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0078 0.0274
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0066 0.0205
Echinococcus granulosus Protein son of sevenless 0.0025 0.004 0.0122
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0024 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0081 0.0284
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0016 0.0039
Schistosoma mansoni regulator of G protein signaling 0.0035 0.0071 0.0222
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0165 0.0164
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Echinococcus multilocularis dna polymerase eta 0.0044 0.0097 0.0096
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.0409 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Brugia malayi beta-lactamase family protein 0.0146 0.0409 0.1899
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0015 0.001 0.0009
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0053 0.0125 0.2875
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0108 0.2461
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.001 0.0009
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0331 0.0661
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0013 0.0029
Leishmania major importin beta-1 subunit, putative 0.0023 0.0033 0.0571
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.005 0.0117 0.2678
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.0409 0.082
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0024 0.011
Schistosoma mansoni cpg binding protein 0.0028 0.0049 0.015
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0165 0.0524
Mycobacterium tuberculosis Conserved protein 0.0146 0.0409 0.082
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0443
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0053 0.0125 0.0449
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Onchocerca volvulus Huntingtin homolog 0.0239 0.0692 0.3187
Trypanosoma brucei unspecified product 0.0019 0.0021 0.0443
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0024 0.007
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0053 0.0125 0.2875
Plasmodium falciparum importin beta, putative 0.0028 0.0049 0.3414
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0013 0.027
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0015 0.001 0.0028
Schistosoma mansoni cpg binding protein 0.003 0.0053 0.0166
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.001 0.0048
Toxoplasma gondii ABC1 family protein 0.0146 0.0409 1
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.0053 0.0125 0.0236
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0049 0.1144
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0025 0.004 0.0122
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0327
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0103
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.0261 0.1213
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Brugia malayi Pre-SET motif family protein 0.0202 0.058 0.2694
Onchocerca volvulus 0.0035 0.0071 0.0289
Echinococcus multilocularis musashi 0.0026 0.0044 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0081 0.0267
Schistosoma mansoni hypothetical protein 0.0302 0.0885 0.2829
Loa Loa (eye worm) hypothetical protein 0.0239 0.0692 0.3214
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0087 0.0366
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0115
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.0053 0.0125 0.0236
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.1608 0.4865 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0309 0.0906 0.4209
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0256
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0081 0.0374
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.065 0.2076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0024 0.0022
Echinococcus granulosus lamin dm0 0.0026 0.0044 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0409 0.1519
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0024 0.007
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0039 0.0715
Brugia malayi steroid hormone receptor 0.002 0.0024 0.011
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0025 0.004 0.0038
Schistosoma mansoni thyroid hormone receptor 0.002 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0327
Mycobacterium tuberculosis Conserved hypothetical protein 0.0053 0.0125 0.0236
Schistosoma mansoni smad1 5 8 and 0.0034 0.0066 0.0205
Mycobacterium ulcerans lipase LipD 0.0146 0.0409 0.082
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0021 0.0022
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0049 0.0048
Schistosoma mansoni Smad4 0.0015 0.0009 0.0023
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.0409 0.082
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Loa Loa (eye worm) RasGEF domain-containing protein 0.0025 0.004 0.0183
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.065 0.2076
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0015 0.001 0.0048
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0242 0.1124
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0015 0.001 0.0028
Onchocerca volvulus 0.0015 0.001 0.0007
Brugia malayi MH1 domain containing protein 0.0019 0.002 0.0092
Entamoeba histolytica hypothetical protein 0.0023 0.0033 0.0046
Echinococcus granulosus patatin phospholipase domain containing protein 0.0015 0.001 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Mycobacterium tuberculosis Conserved protein 0.0146 0.0409 0.082
Onchocerca volvulus 0.0015 0.001 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.065 0.0648
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0225 0.065 0.3019
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0015 0.001 0.0048
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0061 0.1266
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0013 0.0256
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0294 0.0585
Echinococcus granulosus regulator of G protein signaling 7 0.0035 0.0071 0.0222
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0033 0.0571
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0015 0.001 0.0028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0409 0.1304
Schistosoma mansoni dishevelled 0.0035 0.0071 0.0222
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0024 0.007
Loa Loa (eye worm) Smad1 0.0034 0.0066 0.0303
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0015 0.001 0.0028
Echinococcus granulosus geminin 0.1036 0.3124 1
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0044 0.0202
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0006 0.0029
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.0409 0.082
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0024 0.007
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0117 0.281
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Treponema pallidum NADH oxidase 0.0017 0.0013 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Trypanosoma brucei Flagellar Member 6 0.0015 0.001 0.018
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0081 0.0284
Trypanosoma brucei polo-like protein kinase 0.0092 0.0242 0.5898
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0081 1
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Echinococcus granulosus p2X purinoceptor 4 0.0066 0.0165 0.0524
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0128 0.2964
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0013 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0098 0.0261 0.0832
Trypanosoma brucei isocitrate dehydrogenase, putative 0.005 0.0117 0.281
Schistosoma mansoni dishevelled 0.0035 0.0071 0.0222
Trypanosoma cruzi hypothetical protein 0.0025 0.004 0.0742
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0061 0.1266
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0242 0.0771
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0053 0.0125 1
Brugia malayi beta-lactamase 0.0146 0.0409 0.1899
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0044 0.0201
Brugia malayi hypothetical protein 0.0025 0.0039 0.018
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0061 0.1423
Trichomonas vaginalis set domain proteins, putative 0.023 0.0665 0.2484
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0007 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0005
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0009 0.0007
Brugia malayi Calcitonin receptor-like protein seb-1 0.0309 0.0906 0.421
Giardia lamblia DINP protein human, muc B family 0.0019 0.0021 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0101 0.036
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0025 0.004 0.0122
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.009
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Loa Loa (eye worm) RasGEF domain-containing protein 0.0025 0.004 0.0183
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0015 0.001 0.0028
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0013 0.0078
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0081 0.0146
Toxoplasma gondii exonuclease III APE 0.0039 0.0081 0.1775
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0013 0.0078
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0432 0.128 0.2615
Brugia malayi MH2 domain containing protein 0.0015 0.0009 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0048 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0024 0.0108
Onchocerca volvulus 0.002 0.0024 0.0069
Echinococcus granulosus GPCR family 2 0.0098 0.0261 0.0832
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0038
Echinococcus granulosus voltage gated potassium channel 0.0015 0.001 0.0028
Leishmania major protein kinase, putative 0.0016 0.0011 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.0028
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0024 0.0022
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0024 0.0022
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0053 0.0125 0.0578
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0024 0.0108
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0015 0.001 0.0028
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0066 0.0064
Schistosoma mansoni Smad4 0.0034 0.0066 0.0205
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0013 0.0006
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0062
Echinococcus granulosus segment polarity protein dishevelled 0.0035 0.0071 0.0222
Loa Loa (eye worm) RasGEF domain-containing protein 0.0025 0.004 0.0183
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0024 0.0022
Brugia malayi chromobox protein homolog 3 0.0038 0.0078 0.0365
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.065 0.2076
Brugia malayi MH1 domain containing protein 0.0034 0.0066 0.0305
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0053 0.0165
Brugia malayi MH2 domain containing protein 0.0493 0.1468 0.6821
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0268
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.0017
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0718 0.2152 1
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0409 0.1519
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0081 0.1775
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0534 0.1991
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0039 0.0715
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0194
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.0011 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0024 0.011
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Brugia malayi RasGEF domain containing protein 0.0025 0.004 0.0185
Echinococcus multilocularis snurportin 1 0.0302 0.0885 0.0883
Echinococcus multilocularis expressed conserved protein 0.0016 0.0011 0.001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Schistosoma mansoni smad 0.0015 0.0009 0.0023
Echinococcus granulosus intermediate filament protein 0.0026 0.0044 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Schistosoma mansoni smad1 5 8 and 0.0034 0.0066 0.0205
Onchocerca volvulus 0.0146 0.0409 0.1865
Toxoplasma gondii hypothetical protein 0.0035 0.0071 0.1518
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.065 0.2076
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0409 1
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0015 0.001 0.0048
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi N-terminal motif family protein 0.0025 0.004 0.0185
Schistosoma mansoni hypothetical protein 0.1036 0.3124 1
Brugia malayi Isocitrate dehydrogenase 0.005 0.0117 0.0543
Echinococcus multilocularis geminin 0.1036 0.3124 0.3122
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0021 0.0057
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0098 0.0261 0.026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0024 0.0022
Brugia malayi hypothetical protein 0.0035 0.0071 0.0329
Loa Loa (eye worm) AGC/PKG protein kinase 0.0016 0.0011 0.005
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0049 0.1144
Trichomonas vaginalis rotamase, putative 0.0033 0.0063 0.0216
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0242 0.1089
Brugia malayi nuclear hormone receptor 0.002 0.0024 0.011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0053 0.0051
Brugia malayi nuclear receptor NHR-88 0.002 0.0024 0.011
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0019
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0024 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Schistosoma mansoni hypothetical protein 0.0211 0.0608 0.1941
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.065 0.0648
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0294 0.0585
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0108
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.0028
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.001 0.0028
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.001 0.0028
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0024 0.011
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0024 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Mycobacterium tuberculosis Probable reductase 0.0109 0.0294 0.0585
Plasmodium falciparum thioredoxin reductase 0.0017 0.0013 0.027
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0049 0.0981
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.001 0.0009
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0117 0.2678
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0013 0.0062
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0025 0.004 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0061 0.1266
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0101 0.036
Schistosoma mansoni hypothetical protein 0.1036 0.3124 1
Echinococcus multilocularis Protein son of sevenless 0.0025 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0152 0.0428 0.1987
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0015 0.001 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0024 0.0108
Echinococcus multilocularis ras GTP exchange factor 0.0025 0.004 0.0038
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0024 0.011
Echinococcus granulosus regulator of G protein signaling 7 0.0035 0.0071 0.0222
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.001 0.0009
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.001 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Leishmania major hypothetical protein, conserved 0.0146 0.0409 1
Trypanosoma brucei protein kinase A regulatory subunit 0.0015 0.001 0.018
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.0409 0.082
Loa Loa (eye worm) DIX domain-containing protein 0.0035 0.0071 0.0327
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0015 0.001 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.001 0.0028
Echinococcus multilocularis muscleblind protein 0.0152 0.0428 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0242 0.0771
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0097 0.0453
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0013 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0409 0.1519
Schistosoma mansoni chromobox protein 0.0068 0.0169 0.0536
Schistosoma mansoni hypothetical protein 0.0036 0.0073 0.023
Loa Loa (eye worm) hypothetical protein 0.0098 0.0261 0.1213
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0169 0.0615
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.001 0.0028
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0024 0.007
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.005 0.0117 0.2678
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0117 0.0115
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0015 0.001 0.0009
Brugia malayi hypothetical protein 0.0148 0.0416 0.1931
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0015 0.001 0.0009
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0035 0.0071 0.0222
Echinococcus multilocularis p2X purinoceptor 4 0.0066 0.0165 0.0164
Echinococcus multilocularis expressed protein 0.0033 0.0063 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.0409 0.082
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Plasmodium vivax glutathione reductase, putative 0.0048 0.0108 0.2461
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.0409 0.0407
Echinococcus multilocularis son of sevenless 1 0.0025 0.004 0.0038
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0242 0.0241
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Onchocerca volvulus 0.0148 0.0416 0.1897
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0009 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0087 0.0307
Giardia lamblia Fructose-bisphosphate aldolase 0.0884 0.2659 1
Echinococcus granulosus smad 0.0034 0.0066 0.0205
Brugia malayi SET domain containing protein 0.0013 0.0002 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Schistosoma mansoni smad 0.0034 0.0066 0.0205
Entamoeba histolytica hypothetical protein 0.0036 0.0073 0.0199
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Loa Loa (eye worm) hypothetical protein 0.0718 0.2152 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.0428 0.1987
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0103
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0081 0.0146
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0169 0.0783
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0053 0.0125 0.2875
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0081 0.0079
Brugia malayi isocitrate dehydrogenase 0.005 0.0117 0.0543
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.001 0.0048
Schistosoma mansoni coup transcription factor 0.002 0.0024 0.007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.0409 0.082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0327
Schistosoma mansoni cpg binding protein 0.003 0.0053 0.0166
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0331 0.0661
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Mycobacterium leprae conserved hypothetical protein 0.0146 0.0409 0.082
Brugia malayi beta-lactamase family protein 0.0146 0.0409 0.1899
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0013 1
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0409 0.1519
Trichomonas vaginalis ras GTP exchange factor, putative 0.0025 0.004 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0021 0.0022
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0428 0.0426
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.0505 0.2314
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0053 0.0125 0.0395
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0015 0.001 0.0046
Leishmania major trypanothione reductase 0.0048 0.0108 0.2461
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0007
Brugia malayi latrophilin 2 splice variant baaae 0.0211 0.0608 0.2824
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Brugia malayi hypothetical protein 0.0036 0.0073 0.0341
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Brugia malayi MH2 domain containing protein 0.0034 0.0066 0.0305
Echinococcus multilocularis isocitrate dehydrogenase 0.005 0.0117 0.0115
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0242 0.0891
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0024 0.011
Brugia malayi RNA, U transporter 1 0.0081 0.0209 0.0969
Trichomonas vaginalis esterase, putative 0.0146 0.0409 0.1519
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0024 0.007
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0015 0.001 0.0028
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0097 0.2328
Brugia malayi CHD4 protein 0.0013 0.0002 0.0007
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0053 0.0125 0.0432
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0934 0.281 0.5766
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0024 0.0069
Schistosoma mansoni dep domain containing protein 0.0035 0.0071 0.0222
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0013 0.0006
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0432 0.128 0.2615
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0053 0.0125 0.2875
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0024 0.007
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.0028
Onchocerca volvulus 0.0146 0.0409 0.1865
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0025 0.004 0.0122
Schistosoma mansoni P2X receptor subunit 0.0066 0.0165 0.0524
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0033 0.0103
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0117 0.2678
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0015 0.001 0.0017
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0081 0.0376
Loa Loa (eye worm) transcription factor SMAD2 0.0493 0.1468 0.682
Echinococcus granulosus ras GTP exchange factor 0.0025 0.004 0.0122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0021 0.0022
Brugia malayi glutathione reductase 0.0048 0.0108 0.0503
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.0409 0.1304
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0081 0.0228
Schistosoma mansoni z-protein (S1r protein) 0.0035 0.0071 0.0222
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.001 0.0028
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.005 0.0117 0.9315
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0057 0.1184
Schistosoma mansoni hypothetical protein 0.0098 0.0261 0.0832
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0053 0.0165
Brugia malayi hypothetical protein 0.0016 0.0012 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0147
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0169 0.0615
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0039 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.1608 0.4865 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0024 0.007
Plasmodium vivax importin-beta 2, putative 0.0028 0.0049 0.0981
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.001 0.0028
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0013 0.0256
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0024 0.007
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0063 0.0293
Brugia malayi hypothetical protein 0.0239 0.0692 0.3215
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0247
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0061 0.0151
Trypanosoma brucei cAMP response protein 1, putative 0.0015 0.001 0.018
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0024 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0443
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0021 0.0095
Onchocerca volvulus 0.003 0.0054 0.0208
Loa Loa (eye worm) hypothetical protein 0.0211 0.0608 0.2822
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0409 0.1519
Loa Loa (eye worm) beta-lactamase 0.0146 0.0409 0.1897
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0409 1
Mycobacterium ulcerans beta-lactamase 0.0146 0.0409 0.082
Brugia malayi N-terminal motif family protein 0.0025 0.004 0.0185
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0024 0.0036 0.011
Plasmodium falciparum glutathione reductase 0.0017 0.0013 0.027
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0053 0.0125 0.2875
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0789 0.2951
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0024 0.011
Brugia malayi regulator of G-protein signaling egl-10 0.0035 0.0071 0.0329
Schistosoma mansoni lamin 0.0026 0.0044 0.0134
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0309 0.0906 0.421
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0057 0.1184
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0053 0.0165
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0021 0.0062
Echinococcus multilocularis Smad4 0.0034 0.0066 0.0064
Leishmania major protein kinase, putative 0.0016 0.0011 0.0023
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0015 0.001 0.0028
Brugia malayi Smad1 0.0034 0.0066 0.0305
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0009 0.0023
Echinococcus granulosus cpg binding protein 0.003 0.0053 0.0166
Schistosoma mansoni ap endonuclease 0.0039 0.0081 0.0254
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0081 0.1775
Schistosoma mansoni nuclear hormone receptor 0.002 0.0024 0.007
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0024 0.011
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0009 0.0041
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.001 0.0028
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0024 0.007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0024 0.007
Echinococcus granulosus cGMP dependent protein kinase 0.0016 0.0011 0.0031
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0024 0.0022
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0021 0.0022
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0053 0.0125 0.3003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0081 0.0254
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0024 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0024 0.011
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.005 0.0117 0.0369
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.0409 0.082
Loa Loa (eye worm) hypothetical protein 0.0146 0.0409 0.1897
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0046
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0006
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0081 0.1923
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0035 0.0071 0.0329
Schistosoma mansoni rotamase 0.0033 0.0063 0.0197
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0066 0.0205
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0884 0.2659 1
Mycobacterium leprae Probable lipase LipE 0.0146 0.0409 0.082
Leishmania major hypothetical protein, conserved 0.0025 0.0039 0.0715
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0097 0.2187
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0046
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0015 0.001 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.0183
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0024 0.011
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0108 0.0107
Onchocerca volvulus Huntingtin homolog 0.0239 0.0692 0.3187
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0011 0.0031
Echinococcus granulosus cGMP dependent protein kinase 1 0.0016 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.0201
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0015 0.001 0.0048
Brugia malayi ecdysteroid receptor 0.002 0.0024 0.011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0078 0.0325
Schistosoma mansoni lamin 0.0026 0.0044 0.0134
Loa Loa (eye worm) isocitrate dehydrogenase 0.005 0.0117 0.0542
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0884 0.2659 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.005 0.0117 0.0115
Echinococcus multilocularis chromobox protein 1 0.0068 0.0169 0.0167
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0066 0.0205
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0108 0.0501
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0081 0.6174
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0025 0.004 0.0072
Onchocerca volvulus 0.0026 0.0044 0.0162
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0505 0.1881
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0013 0.0256
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.1608 0.4865 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0016 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0063 0.0216
Loa Loa (eye worm) hypothetical protein 0.0239 0.0692 0.3214

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 43 uM Inhibition of Akt1 by fluorescence polarization assay ChEMBL. 19179081

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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