TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 332.353 | Formula: C20H16N2O3
H donors: 2 H acceptors: 2 LogP: 2.68 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc2c(c1)c1CCn3c(c1[nH]2)c(O)c1c(c3=O)cccc1
InChi: 1S/C20H16N2O3/c1-25-11-6-7-16-15(10-11)12-8-9-22-18(17(12)21-16)19(23)13-4-2-3-5-14(13)20(22)24/h2-7,10,21,23H,8-9H2,1H3
InChiKey: KZMNRDNUSFASCT-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Echinococcus multilocularis	dynamin 1	0.0076	0.0073	0.0081
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	uncoordinated protein 104	0.0076	0.0073	0.0068
Loa Loa (eye worm)	oxysterol binding protein	0.0076	0.0073	0.0068
Leishmania major	folate/biopterin transporter, putative	0.0097	0.0113	1
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0076	0.0073	0.0081
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Brugia malayi	serine/threonine-protein kinase 6	0.0081	0.0083	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0262	0.0257
Loa Loa (eye worm)	TK/EPH protein kinase	0.0059	0.0039	0.0034
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus multilocularis	oxysterol binding protein 3	0.0076	0.0073	0.0081
Trichomonas vaginalis	conserved hypothetical protein	0.0831	0.1557	1
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0076	0.0073	0.0081
Echinococcus granulosus	calcium dependent secretion activator 1	0.0076	0.0073	0.0081
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	Immunoglobulin	0.0113	0.0145	0.0167
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0145	0.0139
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0059	0.0039	0.0034
Echinococcus granulosus	pleckstrin y domain containing family A	0.0076	0.0073	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0145	0.0139
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0059	0.0039	0.0034
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0079	0.0079	0.0088
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0059	0.0039	0.0034
Echinococcus multilocularis	Immunoglobulin	0.0113	0.0145	0.0167
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Brugia malayi	PXA domain containing protein	0.0831	0.1557	0.1552
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0393	0.0697	0.0692
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0059	0.0039	0.0026
Echinococcus multilocularis	transcription factor collier	0.0172	0.0262	0.0307
Brugia malayi	Receptor family ligand binding region containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0076	0.0073	0.0081
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Oxysterol-binding protein	0.0076	0.0073	0.0068
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0059	0.0039	0.0251
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus granulosus	myotubularin protein 13	0.0076	0.0073	0.0081
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0059	0.0039	0.004
Echinococcus granulosus	semaphorin 1A	0.0393	0.0697	0.0827
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0059	0.0039	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	tyrosine protein kinase shark	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0076	0.0073	0.0469
Entamoeba histolytica	hypothetical protein	0.0076	0.0073	0.0224
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Onchocerca volvulus	outspread protein homolog	0.0076	0.0073	0.0199
Echinococcus multilocularis	epidermal growth factor receptor	0.0059	0.0039	0.004
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0097	0.0113	1
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0059	0.0039	0.0034
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0076	0.0073	0.4577
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Schistosoma mansoni	regulator of G protein signaling	0.0831	0.1557	0.1546
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0059	0.0039	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Brugia malayi	Syntrophin-1	0.0076	0.0073	0.0068
Loa Loa (eye worm)	sema domain-containing protein	0.0393	0.0697	0.0692
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0076	0.0073	0.0224
Schistosoma mansoni	protein kinase	0.0079	0.0079	0.0066
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0079	0.0079	0.5423
Echinococcus granulosus	tyrosine protein kinase csk	0.0059	0.0039	0.004
Echinococcus multilocularis	exocyst complex component 2	0.0172	0.0262	0.0307
Brugia malayi	regulator of G-protein signaling egl-10	0.0831	0.1557	0.1552
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Brugia malayi	hypothetical protein	0.0393	0.0697	0.0692
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0097	0.0113	1
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0262	0.0257
Echinococcus multilocularis	c src tyrosine kinase	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0831	0.1557	0.1552
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0059	0.0039	0.004
Echinococcus multilocularis	FL cytokine receptor	0.0059	0.0039	0.004
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0059	0.0039	0.004
Loa Loa (eye worm)	AUR protein kinase	0.0081	0.0083	0.0078
Schistosoma mansoni	zinc finger protein	0.0076	0.0073	0.006
Brugia malayi	PXA domain containing protein	0.0831	0.1557	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0831	0.1557	0.1552
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0172	0.0261	0.0255
Trichomonas vaginalis	centaurin gamma, putative	0.0076	0.0073	0.0469
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0113	0.0145	0.0132
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus granulosus	integrin linked protein kinase	0.0059	0.0039	0.004
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0076	0.0073	0.0081
Entamoeba histolytica	hypothetical protein, conserved	0.0076	0.0073	0.0224
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Toxoplasma gondii	AtPH1 family protein	0.0076	0.0073	0.4577
Toxoplasma gondii	protein kinase domain-containing protein	0.0097	0.0113	1
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0076	0.0073	0.0068
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0059	0.0039	0.0034
Brugia malayi	MAX-1A	0.0076	0.0073	0.0068
Loa Loa (eye worm)	PH domain-containing protein	0.0076	0.0073	0.0068
Giardia lamblia	Aurora kinase	0.0081	0.0083	1
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0076	0.0073	0.0081
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0059	0.0039	0.0034
Brugia malayi	Raf kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	protein kinase	0.0079	0.0079	0.0066
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0076	0.0073	0.0081
Echinococcus granulosus	tyrosine protein kinase csk	0.0059	0.0039	0.004
Schistosoma mansoni	serine/threonine protein kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Trichomonas vaginalis	conserved hypothetical protein	0.0831	0.1557	1
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	serine/threonine protein kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Brugia malayi	SH2 domain containing protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	AUR protein kinase	0.0081	0.0083	0.0078
Trypanosoma cruzi	NIMA-related kinase, putative	0.0097	0.0113	1
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0831	0.1557	0.1546
Echinococcus granulosus	receptor type guanylyl cyclase	0.0059	0.0039	0.004
Echinococcus granulosus	raf serine:threonine protein kinase	0.0059	0.0039	0.004
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.0097	0.0113	1
Echinococcus granulosus	pdz domain containing protein	0.0076	0.0073	0.0081
Echinococcus granulosus	neuroglian	0.0113	0.0145	0.0167
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0059	0.0039	0.004
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0059	0.0039	0.004
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	RGS-3 protein	0.0831	0.1557	0.1552
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0118	0.0155	0.0149
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Toxoplasma gondii	hypothetical protein	0.0076	0.0073	0.4577
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Echinococcus granulosus	regulator of G protein signaling 7	0.0831	0.1557	0.1856
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0059	0.0039	0.004
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0076	0.0073	0.0199
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0059	0.0039	0.0026
Echinococcus multilocularis	tyrosine protein kinase	0.0059	0.0039	0.004
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0081	0.0083	0.5966
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0081	0.0083	0.0292
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	dynamin	0.0076	0.0073	0.006
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	tyrosine protein kinase csk	0.0059	0.0039	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0076	0.0073	0.0224
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0831	0.1557	1
Brugia malayi	Variant SH3 domain containing protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	roundabout 2	0.0118	0.0155	0.0179
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0076	0.0073	0.0081
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Schistosoma mansoni	cell adhesion molecule	0.0118	0.0155	0.0142
Toxoplasma gondii	aurora kinase	0.0081	0.0083	0.5966
Brugia malayi	hypothetical protein	0.0831	0.1557	0.1552
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0059	0.0039	0.0251
Echinococcus granulosus	dynamin 1	0.0076	0.0073	0.0081
Echinococcus multilocularis	aurora kinase A	0.0081	0.0083	0.0093
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0059	0.0039	0.004
Schistosoma mansoni	vesicular amine transporter	0.0115	0.015	0.0137
Trichomonas vaginalis	TK family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus granulosus	epidermal growth factor receptor	0.0059	0.0039	0.004
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	Pleckstrin y	0.0076	0.0073	0.0081
Loa Loa (eye worm)	TK/Met protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0076	0.0073	0.0224
Entamoeba histolytica	hypothetical protein	0.0097	0.0113	0.0489
Trichomonas vaginalis	centaurin/arf, putative	0.0076	0.0073	0.0469
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0076	0.0073	0.0081
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0064	0.0049	0.0052
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	protein kinase	0.0059	0.0039	0.004
Echinococcus granulosus	beta-adrenergic receptor kinase	0.3927	0.7647	0.914
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0076	0.0073	0.0081
Entamoeba histolytica	hypothetical protein	0.0172	0.0262	0.1469
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0076	0.0073	0.0081
Echinococcus multilocularis	regulator of G protein signaling 3	0.0831	0.1557	0.1856
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus granulosus	tyrosine kinase	0.0059	0.0039	0.004
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	protein tyrosine kinase	0.0059	0.0039	0.0026
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0076	0.0073	0.4577
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0113	0.0145	0.0132
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trypanosoma brucei	aurora B kinase	0.0081	0.0083	0.5966
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0076	0.0073	0.0068
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0219	0.0354	0.0349
Echinococcus multilocularis	rac serine:threonine kinase	0.0097	0.0113	0.0129
Echinococcus multilocularis	integrin linked protein kinase	0.0059	0.0039	0.004
Brugia malayi	Plekhf2 protein	0.0076	0.0073	0.0068
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0172	0.0262	0.1683
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	CAMK family protein kinase	0.0059	0.0039	0.0251
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0097	0.0113	1
Brugia malayi	Tyrosine-protein kinase abl-1	0.0059	0.0039	0.0034
Brugia malayi	Plexin repeat family protein	0.0928	0.1748	0.1743
Brugia malayi	ephrin receptor 1 precursor	0.0059	0.0039	0.0034
Loa Loa (eye worm)	PXA domain-containing protein	0.0831	0.1557	0.1552
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0083	0.0536
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	axis inhibition protein axin	0.0831	0.1557	0.1856
Brugia malayi	Protein kinase domain containing protein	0.0097	0.0113	0.0108
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.4292	0.8366	0.8365
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0097	0.0113	1
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0081	0.0083	0.5966
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0831	0.1557	0.1856
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0081	0.0083	0.0292
Brugia malayi	A-kinase anchor protein 10, precursor	0.0831	0.1557	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0059	0.0039	0.0026
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0393	0.0697	0.0692
Onchocerca volvulus	Putative zinc finger protein	0.0076	0.0073	0.0199
Entamoeba histolytica	hypothetical protein	0.0097	0.0113	0.0489
Trichomonas vaginalis	protein transport protein sec7, putative	0.0076	0.0073	0.0469
Echinococcus granulosus	tyrosine kinase	0.0059	0.0039	0.004
Schistosoma mansoni	syntrophin	0.0076	0.0073	0.006
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	goodpasture antigen-binding protein	0.0076	0.0073	0.006
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	goodpasture antigen-binding protein	0.0076	0.0073	0.006
Brugia malayi	Furin-like cysteine rich region family protein	0.0059	0.0039	0.0034
Onchocerca volvulus		0.0393	0.0697	0.3849
Schistosoma mansoni	dynamin	0.0076	0.0073	0.006
Toxoplasma gondii	hypothetical protein	0.0076	0.0073	0.4577
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	TBC domain containing protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0076	0.0073	0.0081
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Schistosoma mansoni	hypothetical protein	0.0076	0.0073	0.006
Entamoeba histolytica	p21-activated kinase	0.0097	0.0113	0.0489
Loa Loa (eye worm)	hypothetical protein	0.0393	0.0697	0.0692
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Oxysterol binding protein	0.0076	0.0073	0.0068
Trichomonas vaginalis	hypothetical protein	0.0076	0.0073	0.0469
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	serine/threonine protein kinase	0.3927	0.7647	0.7644
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0076	0.0073	0.0081
Brugia malayi	hypothetical protein	0.0076	0.0073	0.0068
Entamoeba histolytica	hypothetical protein	0.0831	0.1557	1
Echinococcus granulosus	Pleckstrin y	0.0076	0.0073	0.0081
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Trypanosoma brucei	PH domain containing protein, putative	0.0076	0.0073	0.4577
Brugia malayi	hypothetical protein	0.0118	0.0155	0.0149
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0079	0.0079	0.0088
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus granulosus	kinase suppressor of Ras 1	0.0059	0.0039	0.004
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0059	0.0039	0.004
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0059	0.0039	0.004
Echinococcus granulosus	DCC interacting protein 13 beta	0.0076	0.0073	0.0081
Schistosoma mansoni	ephrin receptor	0.0064	0.0049	0.0036
Echinococcus granulosus	tyrosine protein kinase HCK	0.0059	0.0039	0.004
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Brugia malayi	hypothetical protein	0.0393	0.0697	0.0692
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0097	0.0113	1
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.4292	0.8366	0.8365
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	PH domain containing protein	0.0076	0.0073	0.0224
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0059	0.0039	0.004
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0059	0.0039	0.004
Trichomonas vaginalis	STE family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0059	0.0039	0.004
Schistosoma mansoni	serine/threonine-protein kinase	0.0097	0.0113	0.0101
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Loa Loa (eye worm)	hypothetical protein	0.0831	0.1557	0.1552
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0059	0.0039	0.0034
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0079	0.0079	0.5423
Trypanosoma cruzi	PH domain containing protein, putative	0.0076	0.0073	0.4577
Echinococcus granulosus	oxysterol binding protein 9	0.0076	0.0073	0.0081
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0059	0.0039	0.004
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0145	0.0139
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	hypothetical protein	0.0831	0.1557	1
Schistosoma mansoni	hypothetical protein	0.0076	0.0073	0.006
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0172	0.0262	0.1683
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0393	0.0697	0.0692
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Leishmania major	hypothetical protein, conserved	0.0076	0.0073	0.4577
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0076	0.0073	0.4577
Echinococcus multilocularis	protein kinase	0.0059	0.0039	0.004
Brugia malayi	IPT/TIG domain containing protein	0.0172	0.0262	0.0257
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0076	0.0073	0.0081
Echinococcus granulosus	activated cdc42 kinase 1	0.0059	0.0039	0.004
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0059	0.0039	0.004
Echinococcus granulosus	Regulator of G protein signaling 20	0.0831	0.1557	0.1856
Schistosoma mansoni	regulator of G protein signaling	0.0831	0.1557	0.1546
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	tyrosine kinase	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0059	0.0039	0.004
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.0097	0.0113	1
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.0097	0.0113	1
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0076	0.0073	0.0081
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0097	0.0113	0.0489
Schistosoma mansoni	hypothetical protein	0.0393	0.0697	0.0685
Echinococcus granulosus	ephrin type A receptor 4 A	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0928	0.1748	0.1743
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus multilocularis	pdz domain containing protein	0.0076	0.0073	0.0081
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Echinococcus granulosus	oxysterol binding protein 3	0.0076	0.0073	0.0081
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0076	0.0073	0.006
Echinococcus granulosus	regulator of G protein signaling 3	0.0831	0.1557	0.1856
Echinococcus granulosus	twitchin	0.0133	0.0185	0.0215
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.0097	0.0113	1
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus granulosus	epidermal growth factor receptor	0.0059	0.0039	0.004
Echinococcus granulosus	tyrosine protein kinase Srms	0.0059	0.0039	0.004
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0059	0.0039	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0097	0.0113	1
Brugia malayi	probable spectrin beta chain	0.0076	0.0073	0.0068
Schistosoma mansoni	centaurin alpha	0.0076	0.0073	0.006
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	vav2	0.0076	0.0073	0.006
Echinococcus granulosus	beta 1 syntrophin	0.0076	0.0073	0.0081
Loa Loa (eye worm)	SRC-1	0.0059	0.0039	0.0034
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Schistosoma mansoni	plexin	0.0928	0.1748	0.1737
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0076	0.0073	0.4577
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0059	0.0039	0.0034
Brugia malayi	Cytohesin 3	0.0076	0.0073	0.0068
Echinococcus multilocularis	beta 1 syntrophin	0.0076	0.0073	0.0081
Onchocerca volvulus		0.0076	0.0073	0.0199
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.0097	0.0113	0.0728
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	tyrosine protein kinase csk	0.0059	0.0039	0.004
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0076	0.0073	0.0224
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	kinesin light chain, putative	0.0076	0.0073	0.0469
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Echinococcus multilocularis	protein kinase	0.0059	0.0039	0.004
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0076	0.0073	0.4577
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0076	0.0073	0.0081
Trypanosoma brucei	protein kinase, putative	0.0097	0.0113	1
Schistosoma mansoni	hypothetical protein	0.0393	0.0697	0.0685
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0059	0.0039	0.004
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0059	0.0039	0.004
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.0097	0.0113	1
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus granulosus	transcription factor collier	0.0172	0.0262	0.0307
Echinococcus granulosus	tyrosine protein kinase shark	0.0059	0.0039	0.004
Trypanosoma cruzi	aurora B kinase, putative	0.0081	0.0083	0.5966
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus granulosus	tyrosine protein kinase Blk	0.0059	0.0039	0.004
Brugia malayi	Protein kinase domain containing protein	0.0308	0.0529	0.0524
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0076	0.0073	0.4577
Entamoeba histolytica	protein kinase, putative	0.0081	0.0083	0.0292
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0831	0.1557	0.1546
Leishmania major	serine/threonine-protein kinase a, putative	0.0097	0.0113	1
Echinococcus multilocularis	neuroglian	0.0113	0.0145	0.0167
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	hypothetical protein	0.0172	0.0262	0.1469
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0076	0.0073	0.0469
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0064	0.0049	0.0052
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0172	0.0262	0.1683
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0172	0.0262	0.1683
Trichomonas vaginalis	centaurin/arf, putative	0.0076	0.0073	0.0469
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trypanosoma cruzi	PH domain containing protein, putative	0.0076	0.0073	0.4577
Echinococcus multilocularis	regulator of G protein signaling	0.0831	0.1557	0.1856
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	cytohesin 1	0.0076	0.0073	0.0081
Schistosoma mansoni	semaphorin 5-related	0.0393	0.0697	0.0685
Echinococcus multilocularis	tyrosine protein kinase csk	0.0059	0.0039	0.004
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Schistosoma mansoni	growth factor receptor-bound protein	0.0076	0.0073	0.006
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0059	0.0039	0.004
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0059	0.0039	0.0026
Echinococcus granulosus	aurora kinase A	0.0081	0.0083	0.0093
Echinococcus multilocularis	tyrosine kinase	0.0059	0.0039	0.004
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0059	0.0039	0.004
Loa Loa (eye worm)	TK/INSR protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	tyrosin kinase, putative	0.0231	0.0378	0.2233
Trypanosoma brucei	protein kinase, putative	0.0079	0.0079	0.5423
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Brugia malayi	protein-tyrosine kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	GRB2 associated binding protein 3	0.0076	0.0073	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Schistosoma mansoni	hypothetical protein	0.0076	0.0073	0.006
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.3096	0.6013	0.7186
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	transfer RNA-Thr	0.0059	0.0039	0.004
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0059	0.0039	0.004
Loa Loa (eye worm)	TK/DDR protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Schistosoma mansoni	hypothetical protein	0.0076	0.0073	0.006
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0059	0.0039	0.0034
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Schistosoma mansoni	regulator of G protein signaling	0.0831	0.1557	0.1546
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.4292	0.8366	1
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0083	0.0536
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0076	0.0073	0.0081
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	cytohesin 1	0.0076	0.0073	0.0081
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trypanosoma cruzi	NIMA-related kinase, putative	0.0097	0.0113	1
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0059	0.0039	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Loa Loa (eye worm)	TK/ACK protein kinase	0.0059	0.0039	0.0034
Entamoeba histolytica	hypothetical protein	0.0076	0.0073	0.0224
Trichomonas vaginalis	alpha chimerin, putative	0.0076	0.0073	0.0469
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Echinococcus granulosus	defective proboscis extension response	0.0113	0.0145	0.0167
Schistosoma mansoni	serine/threonine protein kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	oxysterol binding protein 1	0.0076	0.0073	0.0081
Loa Loa (eye worm)	rho-GTPase-activating	0.0076	0.0073	0.0068
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0059	0.0039	0.0034
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0076	0.0073	0.0469
Trypanosoma cruzi	PH domain containing protein, putative	0.0076	0.0073	0.4577
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0113	0.0145	0.0167
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	axis inhibition protein axin	0.0831	0.1557	0.1856
Brugia malayi	Fibronectin type III domain containing protein	0.0118	0.0155	0.0149
Echinococcus granulosus	expressed protein	0.0831	0.1557	0.1856
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0076	0.0073	0.006
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0076	0.0073	0.4577
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0113	0.0145	0.0167
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	activated cdc42 kinase 1	0.0059	0.0039	0.004
Brugia malayi	Sema domain containing protein	0.0393	0.0697	0.0692
Loa Loa (eye worm)	hypothetical protein	0.0118	0.0155	0.0149
Schistosoma mansoni	zinc finger protein	0.0076	0.0073	0.006
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Entamoeba histolytica	cell surface protease gp63, putative	0.0172	0.0262	0.1469
Echinococcus granulosus	activated cdc42 kinase 1	0.0059	0.0039	0.004
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0081	0.0083	0.0093
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0076	0.0073	0.0224
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0076	0.0073	0.0081
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Entamoeba histolytica	PH domain containing protein	0.0076	0.0073	0.0224
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0059	0.0039	0.004
Schistosoma mansoni	hypothetical protein	0.0534	0.0974	0.0962
Echinococcus multilocularis	regulator of G protein signaling 7	0.0831	0.1557	0.1856
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0059	0.0039	0.004
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	plexin	0.0534	0.0974	0.0962
Echinococcus multilocularis	axis inhibition protein axin	0.0831	0.1557	0.1856
Brugia malayi	hypothetical protein	0.0831	0.1557	0.1552
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Entamoeba histolytica	hypothetical protein	0.0076	0.0073	0.0224
Echinococcus multilocularis	Oxysterol binding protein 11	0.0076	0.0073	0.0081
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Schistosoma mansoni	regulator of G protein signaling	0.0831	0.1557	0.1546
Echinococcus granulosus	tyrosine kinase	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	beta adrenergic receptor kinase	0.3927	0.7647	0.914
Schistosoma mansoni	protein kinase	0.0081	0.0083	0.0071
Loa Loa (eye worm)	TK/ALK protein kinase	0.0308	0.0529	0.0523
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0083	0.0536
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0534	0.0974	0.0969
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Entamoeba histolytica	hypothetical protein	0.0076	0.0073	0.0224
Schistosoma mansoni	hypothetical protein	0.0172	0.0262	0.0249
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Schistosoma mansoni	hypothetical protein	0.0172	0.0262	0.0249
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Echinococcus granulosus	protein tyrosine kinase	0.0059	0.0039	0.004
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Toxoplasma gondii	Oxysterol-binding protein	0.0076	0.0073	0.4577
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0097	0.0113	0.0108
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0097	0.0113	1
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Brugia malayi	Guanylyl cyclase protein 23	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0145	0.0139
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0059	0.0039	0.004
Schistosoma mansoni	nephrin	0.0118	0.0155	0.0142
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0059	0.0039	0.004
Entamoeba histolytica	pleckstrin homology (PH) domain containing protein	0.0076	0.0073	0.0224
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus granulosus	Pleckstrin y	0.0076	0.0073	0.0081
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0831	0.1557	0.1856
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0831	0.1557	0.1546
Trichomonas vaginalis	protein kinase atn1, putative	0.0059	0.0039	0.0251
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0059	0.0039	0.004
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0079	0.0079	0.5423
Leishmania major	protein kinase, putative	0.0079	0.0079	0.5423
Plasmodium falciparum	PH domain-containing protein, putative	0.0076	0.0073	0.4577
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0059	0.0039	0.004
Echinococcus granulosus	Rho GTPase activating protein 24	0.0076	0.0073	0.0081
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0097	0.0113	0.0489
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	plexin A	0.11	0.2087	0.2082
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	myotubularin-related protein	0.0076	0.0073	0.006
Loa Loa (eye worm)	syntrophin-1	0.0076	0.0073	0.0068
Echinococcus multilocularis	hypothetical protein	0.0393	0.0697	0.0827
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0097	0.0113	0.0489
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0145	0.0139
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0076	0.0073	0.0081
Echinococcus multilocularis	oxysterol binding protein 9	0.0076	0.0073	0.0081
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0059	0.0039	0.004
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Trypanosoma cruzi	Protein kinase B	0.0097	0.0113	1
Loa Loa (eye worm)	hypothetical protein	0.0118	0.0155	0.0149
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0059	0.0039	0.004
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0059	0.0039	0.004
Brugia malayi	PH domain containing protein	0.0076	0.0073	0.0068
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Brugia malayi	Uncoordinated protein 104	0.0076	0.0073	0.0068
Schistosoma mansoni	serine/threonine protein kinase	0.0081	0.0083	0.0071
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Echinococcus multilocularis	regulator of G protein signaling 3	0.0831	0.1557	0.1856
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus granulosus	axis inhibition protein axin	0.0831	0.1557	0.1856
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0059	0.0039	0.004
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Echinococcus multilocularis	actin binding protein anillin	0.0076	0.0073	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0831	0.1557	0.1552
Onchocerca volvulus		0.0076	0.0073	0.0199
Brugia malayi	DNA-binding protein LAG-1	0.0172	0.0262	0.0257
Onchocerca volvulus		0.0076	0.0073	0.0199
Brugia malayi	Pleckstrin Homology Domain	0.0076	0.0073	0.0068
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0059	0.0039	0.0034
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0059	0.0039	0.004
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0059	0.0039	0.004
Brugia malayi	integrin-linked kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	axis inhibition protein axin	0.0831	0.1557	0.1546
Schistosoma mansoni	oxysterol-binding protein 1	0.0076	0.0073	0.006
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0039	0.0251
Echinococcus multilocularis	protein tyrosine kinase	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0059	0.0039	0.0034
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.4292	0.8366	1
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0097	0.0113	1
Loa Loa (eye worm)	TK/CSK protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.4292	0.8366	0.8365
Brugia malayi	Cadps2 protein	0.0076	0.0073	0.0068
Schistosoma mansoni	oxysterol-binding protein 1	0.0076	0.0073	0.006
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Brugia malayi	Variant SH3 domain containing protein	0.0076	0.0073	0.0068
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Trichomonas vaginalis	AGC family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0059	0.0039	0.004
Onchocerca volvulus		0.0076	0.0073	0.0199
Echinococcus multilocularis	tyrosine protein kinase csk	0.0059	0.0039	0.004
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0076	0.0073	0.0068
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0076	0.0073	0.0081
Schistosoma mansoni	axis inhibition protein axin	0.0831	0.1557	0.1546
Onchocerca volvulus		0.0928	0.1748	1
Schistosoma mansoni	fibrocystin l	0.0172	0.0262	0.0249
Plasmodium falciparum	protein kinase, putative	0.0079	0.0079	0.5423
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0059	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trichomonas vaginalis	conserved hypothetical protein	0.0831	0.1557	1
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Onchocerca volvulus		0.0076	0.0073	0.0199
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0076	0.0073	0.4577
Echinococcus granulosus	regulator of G protein signaling 3	0.0831	0.1557	0.1856
Entamoeba histolytica	protein kinase domain containing protein	0.0079	0.0079	0.0265
Echinococcus granulosus	semaphorin 5B	0.0393	0.0697	0.0827
Brugia malayi	serine/threonine protein kinase 6	0.0081	0.0083	0.0078
Leishmania major	protein kinase, putative	0.0081	0.0083	0.5966
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0076	0.0073	0.0469
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Onchocerca volvulus		0.0076	0.0073	0.0199
Echinococcus granulosus	tyrosine protein kinase	0.0059	0.0039	0.004
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	myotubularin protein 13	0.0076	0.0073	0.0081
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0059	0.0039	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Plasmodium falciparum	oxysterol-binding protein, putative	0.0076	0.0073	0.4577
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.0097	0.0113	1
Plasmodium vivax	hypothetical protein, conserved	0.0076	0.0073	0.4577
Loa Loa (eye worm)	TK/FAK protein kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	activin receptor type	0.0079	0.0079	0.0088
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.0097	0.0113	0.0728
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Entamoeba histolytica	PH domain containing protein	0.0076	0.0073	0.0224
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	serine/threonine protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trypanosoma cruzi	PH domain containing protein, putative	0.0076	0.0073	0.4577
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0831	0.1557	0.1552
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0076	0.0073	0.0469
Brugia malayi	SRC-1	0.0059	0.0039	0.0034
Echinococcus granulosus	tyrosine protein kinase pr2	0.0059	0.0039	0.004
Loa Loa (eye worm)	TK/ROR protein kinase	0.0059	0.0039	0.0034
Plasmodium vivax	PH domain containing protein	0.0076	0.0073	0.4577
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Schistosoma mansoni	ephrin receptor	0.0059	0.0039	0.0026
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	Pleckstrin y	0.0076	0.0073	0.0081
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0059	0.0039	0.004
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0831	0.1557	0.1856
Loa Loa (eye worm)	cytohesin 3	0.0076	0.0073	0.0068
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0076	0.0073	0.0224
Loa Loa (eye worm)	TK/RYK protein kinase	0.0059	0.0039	0.0034
Echinococcus multilocularis	regulator of G protein signaling 7	0.0831	0.1557	0.1856
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.0097	0.0113	1
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Echinococcus granulosus	Oxysterol binding protein 11	0.0076	0.0073	0.0081
Brugia malayi	Probable exocyst complex component Sec5	0.0172	0.0262	0.0257
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus multilocularis	semaphorin 5B	0.0393	0.0697	0.0827
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	sema domain-containing protein	0.0393	0.0697	0.0692
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0262	0.1683
Onchocerca volvulus		0.0076	0.0073	0.0199
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Echinococcus granulosus	G protein coupled receptor kinase 1	0.3096	0.6013	0.7186
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.0097	0.0113	1
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Schistosoma mansoni	protein kinase	0.0079	0.0079	0.0066
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0076	0.0073	0.4577
Brugia malayi	C-terminal src kinase protein 1	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	heat shock protein 70	0.0059	0.0039	0.004
Brugia malayi	hypothetical protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0059	0.0039	0.004
Echinococcus multilocularis	Pleckstrin y	0.0076	0.0073	0.0081
Brugia malayi	hypothetical protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0831	0.1557	1
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.5123	1	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0059	0.0039	0.004
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0831	0.1557	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0073	0.0068
Schistosoma mansoni	hypothetical protein	0.0076	0.0073	0.006
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0081	0.0083	0.0093
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Entamoeba histolytica	protein kinase , putative	0.0081	0.0083	0.0292
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0076	0.0073	0.0068
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0076	0.0073	0.0081
Entamoeba histolytica	hypothetical protein	0.0076	0.0073	0.0224
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0079	0.0079	0.0088
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0059	0.0039	0.004
Loa Loa (eye worm)	TK/ABL protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0393	0.0697	0.0692
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0172	0.0262	0.1683
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0081	0.0083	0.0292
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0831	0.1557	0.1552
Trypanosoma cruzi	hypothetical protein	0.0076	0.0073	0.4577
Brugia malayi	plexin A	0.11	0.2087	0.2082
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0076	0.0073	0.0081
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	AUR protein kinase	0.0081	0.0083	0.0078
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0076	0.0073	0.0068
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0262	0.0257
Echinococcus multilocularis	plexin a4	0.11	0.2087	0.2489
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0076	0.0073	0.0224
Loa Loa (eye worm)	hypothetical protein	0.0118	0.0155	0.0149
Schistosoma mansoni	regulator of G protein signaling	0.0831	0.1557	0.1546
Echinococcus granulosus	c src tyrosine kinase	0.0059	0.0039	0.004
Echinococcus granulosus	natriuretic peptide receptor 1	0.0059	0.0039	0.004
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0097	0.0113	0.0489
Brugia malayi	Tyrosine-protein kinase PR2	0.0059	0.0039	0.0034
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0097	0.0113	0.0489
Echinococcus multilocularis	expressed protein	0.0831	0.1557	0.1856
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Entamoeba histolytica	hypothetical protein	0.0831	0.1557	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0172	0.0261	0.0255
Echinococcus granulosus	oxysterol binding protein 1	0.0076	0.0073	0.0081
Echinococcus granulosus	serine/threonine protein kinase	0.0097	0.0113	0.0129
Echinococcus granulosus	Immunoglobulin	0.0113	0.0145	0.0167
Schistosoma mansoni	protein kinase	0.0059	0.0039	0.0026
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0097	0.0113	1
Schistosoma mansoni	serine/threonine protein kinase	0.0059	0.0039	0.0026
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0076	0.0073	0.0199
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0076	0.0073	0.006
Entamoeba histolytica	protein kinase domain containing protein	0.0231	0.0378	0.2233
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0831	0.1557	0.1552
Echinococcus granulosus	exocyst complex component 2	0.0172	0.0262	0.0307
Trichomonas vaginalis	centaurin alpha, putative	0.0076	0.0073	0.0469
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0076	0.0073	0.0081
Entamoeba histolytica	hypothetical protein	0.0172	0.0262	0.1469
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0059	0.0039	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Brugia malayi	regulator of G-protein signaling rgs-7	0.0831	0.1557	0.1552
Echinococcus multilocularis	activin receptor type	0.0079	0.0079	0.0088
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0097	0.0113	0.0489
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.0097	0.0113	1
Schistosoma mansoni	rho gtpase activating protein	0.0076	0.0073	0.006
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0079	0.0079	0.5423
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Echinococcus granulosus	regulator of G protein signaling 7	0.0831	0.1557	0.1856
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0145	0.0139
Echinococcus granulosus	Pleckstrin y	0.0076	0.0073	0.0081
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0059	0.0039	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0393	0.0697	0.0692
Schistosoma mansoni	serine/threonine RGC	0.0059	0.0039	0.0026
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.3927	0.7647	0.7646
Echinococcus granulosus	plexin a4	0.11	0.2087	0.2489
Brugia malayi	Sema domain containing protein	0.0393	0.0697	0.0692
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0076	0.0073	0.0469
Echinococcus granulosus	roundabout 2	0.0118	0.0155	0.0179
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0097	0.0113	1
Schistosoma mansoni	hypothetical protein	0.0059	0.0039	0.0026
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0059	0.0039	0.004
Trichomonas vaginalis	centaurin beta, putative	0.0076	0.0073	0.0469
Echinococcus granulosus	tyrosine protein kinase csk	0.0059	0.0039	0.004
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0083	0.0536
Schistosoma mansoni	tyrosine protein kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0262	0.0257
Entamoeba histolytica	protein kinase domain containing protein	0.0081	0.0083	0.0292
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0076	0.0073	0.006
Trichomonas vaginalis	conserved hypothetical protein	0.0831	0.1557	1
Onchocerca volvulus	Protein melted homolog	0.0076	0.0073	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0831	0.1557	0.1552
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Loa Loa (eye worm)	TK protein kinase	0.0059	0.0039	0.0034
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0059	0.0039	0.0034
Echinococcus multilocularis	epidermal growth factor receptor	0.0059	0.0039	0.004
Echinococcus granulosus	insulin receptor	0.0059	0.0039	0.004
Trichomonas vaginalis	protein transport protein sec7, putative	0.0076	0.0073	0.0469
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Schistosoma mansoni	serine/threonine protein kinase	0.5123	1	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0059	0.0039	0.004
Schistosoma mansoni	z-protein (S1r protein)	0.0831	0.1557	0.1546
Brugia malayi	Dynamin	0.0076	0.0073	0.0068
Schistosoma mansoni	serine/threonine-protein kinase	0.0097	0.0113	0.0101
Loa Loa (eye worm)	Plekhf2 protein	0.0076	0.0073	0.0068
Brugia malayi	SH2 domain containing protein	0.0059	0.0039	0.0034
Trichomonas vaginalis	conserved hypothetical protein	0.0831	0.1557	1
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0039	0.0034
Echinococcus multilocularis	insulin receptor	0.0059	0.0039	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0073	0.0469
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0059	0.0039	0.004
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0076	0.0073	0.4577
Schistosoma mansoni	serine/threonine protein kinase	0.3927	0.7647	0.7644
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Leishmania major	protein kinase, putative	0.0097	0.0113	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0059	0.0039	0.004
Entamoeba histolytica	protein kinase, putative	0.0081	0.0083	0.0292
Trichomonas vaginalis	TKL family protein kinase	0.0059	0.0039	0.0251
Loa Loa (eye worm)	TK/FER protein kinase	0.0059	0.0039	0.0034
Brugia malayi	serine/threonine kinase 12	0.0081	0.0083	0.0078
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0059	0.0039	0.0251
Entamoeba histolytica	protein kinase, putative	0.0097	0.0113	0.0489
Leishmania major	hypothetical protein, conserved	0.0076	0.0073	0.4577
Trichomonas vaginalis	AGC family protein kinase	0.0097	0.0113	0.0728
Schistosoma mansoni	tyrosine kinase	0.0059	0.0039	0.0026
Brugia malayi	Dynamin	0.0076	0.0073	0.0068
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0059	0.0039	0.0251
Brugia malayi	hypothetical protein	0.0059	0.0039	0.0034
Entamoeba histolytica	hypothetical protein	0.0172	0.0262	0.1469
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0039	0.0034
Leishmania major	protein kinase, putative	0.0097	0.0113	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL472787

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 975468