Detailed information for compound 1021675

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 582.694 | Formula: C36H34N6O2
  • H donors: 1 H acceptors: 4 LogP: 5.14 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN1CCC(CC1)NC(=O)c1ccc(cc1)c1ccc(cc1C)n1c(=O)ccc2c1c1cc(ccc1nc2)c1cnn(c1)C
  • InChi: 1S/C36H34N6O2/c1-23-18-30(10-11-31(23)24-4-6-25(7-5-24)36(44)39-29-14-16-40(2)17-15-29)42-34(43)13-9-27-20-37-33-12-8-26(19-32(33)35(27)42)28-21-38-41(3)22-28/h4-13,18-22,29H,14-17H2,1-3H3,(H,39,44)
  • InChiKey: LHQLXWLOIGQADE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus mechanistic target of rapamycin (serine/threonine kinase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3-kinase (tor2)-like protein Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania braziliensis target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Toxoplasma gondii target of rapamycin (TOR), putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei phosphatidylinositol 4-kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Neospora caninum Phosphatidylinositol 3-kinase tor2, related Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans frameshifted from upstream TOR2 CDS (CaP19.1905) Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans frameshifted from upsteam TOR2 CDS (CaP19.9461) Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Giardia lamblia GTOR Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K07203 FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) phosphatidylinositol 3 Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus regulator of G protein signaling 3 0.0881 0.158 0.1887
Schistosoma mansoni goodpasture antigen-binding protein 0.0081 0.01 0.01
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0081 0.01 0.0321
Echinococcus multilocularis regulator of G protein signaling 7 0.0881 0.158 0.1887
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0105 0.0642
Leishmania major folate/biopterin transporter, putative 0.0103 0.014 1
Toxoplasma gondii Oxysterol-binding protein 0.0081 0.01 0.7114
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0083 0.0104 0.0125
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0062 0.0064 0.0077
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Echinococcus granulosus regulator of G protein signaling 3 0.0881 0.158 0.1887
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0062 0.0064 0.0077
Brugia malayi plexin A 0.1157 0.209 0.209
Entamoeba histolytica protein kinase , putative 0.0084 0.0105 0.0359
Brugia malayi IPT/TIG domain containing protein 0.0181 0.0285 0.0285
Echinococcus multilocularis plexin a4 0.1157 0.209 0.2497
Schistosoma mansoni zinc finger protein 0.0081 0.01 0.01
Brugia malayi MAX-1A 0.0081 0.01 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0015 0.007
Schistosoma mansoni protein kinase 0.0083 0.0104 0.0104
Onchocerca volvulus 0.0414 0.0715 0.4075
Echinococcus granulosus MAM 0.003 0.0006 0.0007
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.014 0.0584
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Schistosoma mansoni hypothetical protein 0.0062 0.0064 0.0064
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0081 0.01 0.0119
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0062 0.0064 0.0077
Echinococcus multilocularis aurora kinase A 0.0084 0.0105 0.0126
Brugia malayi Syntrophin-1 0.0081 0.01 0.01
Plasmodium vivax hypothetical protein, conserved 0.0081 0.01 0.4708
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0029 0.0029
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi Receptor family ligand binding region containing protein 0.0062 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0081 0.01 0.01
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Echinococcus granulosus Regulator of G protein signaling 20 0.0881 0.158 0.1887
Schistosoma mansoni axis inhibition protein axin 0.0881 0.158 0.158
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Onchocerca volvulus 0.0062 0.0064 0.0365
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0181 0.0285 0.1784
Brugia malayi DNA-binding protein LAG-1 0.0181 0.0285 0.0285
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Echinococcus multilocularis dynamin 1 0.0081 0.01 0.0119
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Echinococcus granulosus natriuretic peptide receptor 1 0.0062 0.0064 0.0077
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0081 0.01 0.01
Echinococcus granulosus myotubularin protein 13 0.0081 0.01 0.0119
Loa Loa (eye worm) RGC/RGC protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus expressed protein 0.0881 0.158 0.1887
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.0064 0.0379
Brugia malayi hypothetical protein 0.0062 0.0064 0.0064
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Srms 0.0062 0.0064 0.0077
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0103 0.014 1
Echinococcus multilocularis expressed protein 0.0881 0.158 0.1887
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0081 0.01 0.01
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Schistosoma mansoni centaurin alpha 0.0081 0.01 0.01
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0062 0.0064 0.0077
Schistosoma mansoni nephrin 0.012 0.0172 0.0172
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Loa Loa (eye worm) AUR protein kinase 0.0084 0.0105 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) serine/threonine protein kinase 0.0062 0.0064 0.0064
Trypanosoma brucei aurora B kinase 0.0084 0.0105 0.6861
Brugia malayi PXA domain containing protein 0.0881 0.158 0.158
Loa Loa (eye worm) TK/Met protein kinase 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0062 0.0064 0.0365
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) TK/CSK protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.014 0.0584
Trypanosoma cruzi PH domain containing protein, putative 0.0081 0.01 0.6342
Schistosoma mansoni ephrin receptor 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0062 0.0064 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Schistosoma mansoni serine/threonine protein kinase 0.4165 0.7654 0.7654
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0062 0.0064 0.0077
Leishmania major serine/threonine-protein kinase a, putative 0.0103 0.014 1
Echinococcus multilocularis pdz domain containing protein 0.0081 0.01 0.0119
Loa Loa (eye worm) hypothetical protein 0.0115 0.0163 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Trypanosoma cruzi PH domain containing protein, putative 0.0081 0.01 0.6342
Echinococcus multilocularis roundabout 2 0.012 0.0172 0.0206
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0062 0.0064 0.0077
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Entamoeba histolytica tyrosin kinase, putative 0.0062 0.0064 0.0088
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0062 0.0064 0.0379
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0029 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.4165 0.7654 0.7654
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.0051 0.1864
Onchocerca volvulus 0.0035 0.0016 0.0088
Brugia malayi hypothetical protein 0.0414 0.0715 0.0715
Loa Loa (eye worm) hypothetical protein 0.0414 0.0715 0.0715
Echinococcus granulosus calcium dependent secretion activator 1 0.0081 0.01 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0243 0.0399 0.2279
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0881 0.158 0.158
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0062 0.0064 0.0077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0083 0.0104 0.7432
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0037 0.0037
Echinococcus granulosus activin receptor type 0.0083 0.0104 0.0125
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Brugia malayi A-kinase anchor protein 10, precursor 0.0881 0.158 0.158
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0881 0.158 0.1887
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis regulator of G protein signaling 3 0.0881 0.158 0.1887
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Toxoplasma gondii AtPH1 family protein 0.0081 0.01 0.7114
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Giardia lamblia Aurora kinase 0.0084 0.0105 1
Trichomonas vaginalis centaurin/arf, putative 0.0081 0.01 0.0606
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0081 0.01 0.7114
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0181 0.0285 0.1535
Leishmania major protein kinase, putative 0.0084 0.0105 0.7524
Schistosoma mansoni oxysterol-binding protein 1 0.0081 0.01 0.01
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0103 0.014 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0051 0.0294
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Echinococcus multilocularis tyrosine kinase 0.0062 0.0064 0.0077
Echinococcus multilocularis activated cdc42 kinase 1 0.0062 0.0064 0.0077
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0103 0.014 1
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0062 0.0064 0.0365
Loa Loa (eye worm) TK/ALK protein kinase 0.0313 0.0529 0.0529
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0084 0.0105 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0064 0.0064
Echinococcus granulosus tyrosine protein kinase csk 0.0062 0.0064 0.0077
Onchocerca volvulus 0.0062 0.0064 0.0365
Plasmodium falciparum calcium-dependent protein kinase 7 0.0103 0.014 1
Schistosoma mansoni hypothetical protein 0.0562 0.099 0.099
Echinococcus multilocularis tyrosine protein kinase csk 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0081 0.01 0.6342
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis receptor type guanylyl cyclase 0.0062 0.0064 0.0077
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0062 0.0064 0.0077
Onchocerca volvulus 0.0081 0.01 0.0569
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Echinococcus multilocularis DCC interacting protein 13 beta 0.0081 0.01 0.0119
Toxoplasma gondii aurora kinase 0.0084 0.0105 0.7524
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0062 0.0064 0.0379
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.4553 0.8371 0.8371
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Schistosoma mansoni vav2 0.0081 0.01 0.01
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0176 0.0276 0.0276
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0081 0.01 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0081 0.01 0.0119
Echinococcus granulosus tyrosine protein kinase HCK 0.0062 0.0064 0.0077
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Onchocerca volvulus Tyrosine kinase homolog 0.0062 0.0064 0.0365
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0062 0.0064 0.0365
Echinococcus multilocularis tyrosine protein kinase shark 0.0062 0.0064 0.0077
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0081 0.01 0.0119
Echinococcus multilocularis Immunoglobulin 0.0115 0.0163 0.0194
Onchocerca volvulus Putative zinc finger protein 0.0081 0.01 0.0569
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0062 0.0064 0.0077
Schistosoma mansoni hypothetical protein 0.0081 0.01 0.01
Echinococcus multilocularis pleckstrin y domain containing family A 0.0081 0.01 0.0119
Echinococcus multilocularis protein tyrosine kinase 0.0062 0.0064 0.0077
Echinococcus granulosus defective proboscis extension response 0.0115 0.0163 0.0194
Echinococcus multilocularis tyrosine protein kinase csk 0.0062 0.0064 0.0077
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Echinococcus multilocularis integrin linked protein kinase 0.0062 0.0064 0.0077
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Brugia malayi probable spectrin beta chain 0.0081 0.01 0.01
Entamoeba histolytica serine/threonine kinase, putative 0.0062 0.0064 0.0088
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0081 0.01 0.0321
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0062 0.0064 0.0064
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0081 0.01 0.4708
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0064 0.0379
Brugia malayi Probable exocyst complex component Sec5 0.0181 0.0285 0.0285
Trichomonas vaginalis protein transport protein sec7, putative 0.0081 0.01 0.0606
Trypanosoma brucei rac serine-threonine kinase, putative 0.0103 0.014 1
Brugia malayi hypothetical protein 0.0881 0.158 0.158
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0081 0.01 0.4708
Schistosoma mansoni zinc finger protein 0.0081 0.01 0.01
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.0051 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0083 0.0104 0.035
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.0051 0.0061
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0062 0.0064 0.4546
Onchocerca volvulus 0.0062 0.0064 0.0365
Loa Loa (eye worm) RGC/RGC protein kinase 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0081 0.01 0.0569
Echinococcus multilocularis calcium dependent secretion activator 1 0.0081 0.01 0.0119
Echinococcus multilocularis Pleckstrin y 0.0081 0.01 0.0119
Echinococcus granulosus tyrosine protein kinase csk 0.0062 0.0064 0.0077
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Echinococcus multilocularis Rho GTPase activating protein 24 0.0081 0.01 0.0119
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.012 0.0172 0.0172
Onchocerca volvulus 0.0081 0.01 0.0569
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Plasmodium falciparum protein kinase, putative 0.0083 0.0104 0.7432
Schistosoma mansoni serine/threonine RGC 0.0062 0.0064 0.0064
Leishmania major protein kinase, putative 0.0083 0.0104 0.7432
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Echinococcus granulosus tyrosine protein kinase 0.0062 0.0064 0.0077
Brugia malayi Regulator of G protein signaling domain containing protein 0.0881 0.158 0.158
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0084 0.0105 0.5459
Onchocerca volvulus 0.0062 0.0064 0.0365
Schistosoma mansoni dynamin 0.0081 0.01 0.01
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Trichomonas vaginalis hypothetical protein 0.0081 0.01 0.0606
Entamoeba histolytica hypothetical protein 0.0103 0.014 0.0584
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0081 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0115 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus epidermal growth factor receptor 0.0062 0.0064 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Echinococcus granulosus protein tyrosine kinase 0.0062 0.0064 0.0077
Schistosoma mansoni protein tyrosine kinase 0.0062 0.0064 0.0064
Schistosoma mansoni serine/threonine-protein kinase 0.0103 0.014 0.014
Trypanosoma cruzi NIMA-related kinase, putative 0.0103 0.014 1
Loa Loa (eye worm) hypothetical protein 0.0881 0.158 0.158
Onchocerca volvulus 0.0062 0.0064 0.0365
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0103 0.014 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0083 0.0104 0.6745
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0081 0.01 0.0569
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0081 0.01 0.0321
Echinococcus granulosus semaphorin 5B 0.0414 0.0715 0.0854
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Echinococcus granulosus ephrin type A receptor 4 A 0.0062 0.0064 0.0077
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Echinococcus multilocularis tyrosine protein kinase csk 0.0062 0.0064 0.0077
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis transcription factor collier 0.0181 0.0285 0.0341
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus protein kinase 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0881 0.158 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.003 0.0163
Echinococcus granulosus exocyst complex component 2 0.0181 0.0285 0.0341
Echinococcus granulosus tyrosine protein kinase Src42A 0.0062 0.0064 0.0077
Echinococcus granulosus tyrosine protein kinase shark 0.0062 0.0064 0.0077
Onchocerca volvulus Protein melted homolog 0.0081 0.01 0.0569
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0081 0.01 0.7114
Echinococcus granulosus retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0062 0.0064 0.0077
Schistosoma mansoni hypothetical protein 0.0414 0.0715 0.0715
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0062 0.0064 0.0077
Trypanosoma cruzi protein kinase, putative 0.0062 0.0064 0.3087
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0081 0.01 0.0119
Loa Loa (eye worm) rho-GTPase-activating 0.0081 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0414 0.0715 0.0715
Loa Loa (eye worm) AUR protein kinase 0.0084 0.0105 0.0105
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.003 0.0163
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni regulator of G protein signaling 0.0881 0.158 0.158
Entamoeba histolytica protein kinase, putative 0.0084 0.0105 0.0359
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Entamoeba histolytica hypothetical protein, conserved 0.0062 0.0064 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0036 0.02
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0081 0.01 0.0119
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0081 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.012 0.0172 0.0172
Brugia malayi TBC domain containing protein 0.0081 0.01 0.01
Trichomonas vaginalis centaurin alpha, putative 0.0081 0.01 0.0606
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Loa Loa (eye worm) hypothetical protein 0.0414 0.0715 0.0715
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Brugia malayi bone morphogenetic protein type 1 receptor 0.0062 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Brugia malayi Egg laying defective protein 4 0.0027 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0081 0.01 0.0119
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0103 0.014 1
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Schistosoma mansoni ephrin receptor 0.0067 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus granulosus tyrosine kinase 0.0062 0.0064 0.0077
Echinococcus granulosus serine/threonine protein kinase 0.0103 0.014 0.0167
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0062 0.0064 0.0077
Echinococcus multilocularis GRB2 associated binding protein 3 0.0081 0.01 0.0119
Brugia malayi Protein kinase domain containing protein 0.0313 0.0529 0.0529
Brugia malayi Protein kinase domain containing protein 0.0103 0.014 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trypanosoma brucei protein kinase, putative 0.0083 0.0104 0.6745
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0062 0.0064 0.0379
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.0051 0.1864
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0081 0.01 0.0119
Brugia malayi ephrin receptor 1 precursor 0.0062 0.0064 0.0064
Echinococcus multilocularis protein KINase family member (kin 25) 0.0062 0.0064 0.0077
Brugia malayi Oxysterol-binding protein 0.0081 0.01 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0081 0.01 0.7114
Echinococcus multilocularis epidermal growth factor receptor 0.0062 0.0064 0.0077
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0062 0.0064 0.0064
Plasmodium falciparum protein kinase, putative 0.0062 0.0064 0.4546
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0084 0.0105 0.0359
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Onchocerca volvulus 0.0062 0.0064 0.0365
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.0051 0.1864
Loa Loa (eye worm) PH domain-containing protein 0.0081 0.01 0.01
Trichomonas vaginalis TK family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Plasmodium falciparum protein kinase, putative 0.0062 0.0064 0.4546
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Schistosoma mansoni hypothetical protein 0.003 0.0006 0.0006
Echinococcus granulosus kinase suppressor of Ras 1 0.0062 0.0064 0.0077
Toxoplasma gondii protein kinase 0.0062 0.0064 0.4546
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0103 0.014 1
Loa Loa (eye worm) hypothetical protein 0.0976 0.1755 0.1755
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Schistosoma mansoni hypothetical protein 0.003 0.0006 0.0006
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0081 0.01 0.0119
Echinococcus granulosus tyrosine protein kinase Src64B 0.0062 0.0064 0.0077
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0037 0.0037
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0062 0.0064 0.0365
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0081 0.01 0.01
Schistosoma mansoni plexin 0.0976 0.1755 0.1755
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Trypanosoma cruzi NIMA-related kinase, putative 0.0103 0.014 1
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0103 0.014 1
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Brugia malayi Guanylyl cyclase protein 23 0.0062 0.0064 0.0064
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0181 0.0285 0.1784
Schistosoma mansoni axis inhibition protein axin 0.0881 0.158 0.158
Echinococcus granulosus retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Echinococcus granulosus tyrosine protein kinase Srms 0.0062 0.0064 0.0077
Entamoeba histolytica hypothetical protein 0.0881 0.158 1
Echinococcus granulosus DCC interacting protein 13 beta 0.0081 0.01 0.0119
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0105 0.0642
Onchocerca volvulus 0.0062 0.0064 0.0365
Brugia malayi protein-tyrosine kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Entamoeba histolytica hypothetical protein 0.0881 0.158 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.003 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.003 0.0163
Echinococcus granulosus GRB2 associated binding protein 3 0.0081 0.01 0.0119
Echinococcus granulosus activated cdc42 kinase 1 0.0062 0.0064 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0083 0.0104 0.0125
Plasmodium falciparum PH domain-containing protein, putative 0.0081 0.01 0.7114
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0051 0.0294
Echinococcus multilocularis activin receptor type 0.0083 0.0104 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0037
Echinococcus multilocularis Ras associated and pleckstrin y 0.0081 0.01 0.0119
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0103 0.014 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0081 0.01 0.0606
Loa Loa (eye worm) hypothetical protein 0.0115 0.0163 0.0163
Echinococcus granulosus Rho GTPase activating protein 24 0.0081 0.01 0.0119
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0081 0.01 0.0606
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica PH domain containing protein 0.0081 0.01 0.0321
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.003 0.211
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0103 0.014 1
Echinococcus granulosus Pleckstrin y 0.0081 0.01 0.0119
Entamoeba histolytica hypothetical protein 0.0181 0.0285 0.1535
Brugia malayi SH2 domain containing protein 0.0062 0.0064 0.0064
Brugia malayi Cytohesin 3 0.0081 0.01 0.01
Brugia malayi Tyrosine-protein kinase PR2 0.0062 0.0064 0.0064
Brugia malayi regulator of G-protein signaling rgs-7 0.0881 0.158 0.158
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) hypothetical protein 0.0115 0.0163 0.0163
Echinococcus granulosus tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0115 0.0163 0.0163
Loa Loa (eye worm) cytohesin 3 0.0081 0.01 0.01
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.0025 0.1731
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.014 0.0584
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK/ACK protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis protein kinase atn1, putative 0.0062 0.0064 0.0379
Echinococcus granulosus activated cdc42 kinase 1 0.0062 0.0064 0.0077
Loa Loa (eye worm) sema domain-containing protein 0.0414 0.0715 0.0715
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0081 0.01 0.0119
Schistosoma mansoni goodpasture antigen-binding protein 0.0081 0.01 0.01
Echinococcus granulosus dynamin 1 0.0081 0.01 0.0119
Echinococcus granulosus pleckstrin y domain containing family A 0.0081 0.01 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0115 0.0163 0.0163
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Echinococcus granulosus tyrosine protein kinase pr2 0.0062 0.0064 0.0077
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0051 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Brugia malayi Plekhf2 protein 0.0081 0.01 0.01
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0181 0.0285 0.1784
Plasmodium falciparum oxysterol-binding protein, putative 0.0081 0.01 0.7114
Echinococcus granulosus raf serine:threonine protein kinase 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.0051 0.3581
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Echinococcus multilocularis Oxysterol binding protein 11 0.0081 0.01 0.0119
Echinococcus granulosus oxysterol binding protein 9 0.0081 0.01 0.0119
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0062 0.0064 0.0077
Echinococcus multilocularis tyrosine kinase 0.0062 0.0064 0.0077
Loa Loa (eye worm) hypothetical protein 0.0181 0.0285 0.0285
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0081 0.01 0.0606
Trichomonas vaginalis centaurin gamma, putative 0.0081 0.01 0.0606
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) AUR protein kinase 0.0084 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0221 0.0359 0.0359
Loa Loa (eye worm) RGC/RGC protein kinase 0.0062 0.0064 0.0064
Toxoplasma gondii protein kinase domain-containing protein 0.0062 0.0064 0.4546
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi SH2 domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0027 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) AGC/AKT protein kinase 0.0103 0.014 0.014
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0027 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK/ABL protein kinase 0.0062 0.0064 0.0064
Brugia malayi Plexin repeat family protein 0.0976 0.1755 0.1755
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0881 0.158 0.158
Echinococcus granulosus integrin linked protein kinase 0.0062 0.0064 0.0077
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Leishmania major protein kinase, putative 0.0062 0.0064 0.4546
Brugia malayi serine/threonine-protein kinase 6 0.0084 0.0105 0.0105
Brugia malayi Variant SH3 domain containing protein 0.0081 0.01 0.01
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.0051 0.0061
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0062 0.0064 0.0077
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis Regulator of G protein signaling 20 0.0881 0.158 0.1887
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0062 0.0064 0.0077
Plasmodium falciparum serine/threonine protein kinase, putative 0.0084 0.0105 0.7524
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) TK/ROR protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Echinococcus granulosus regulator of G protein signaling 7 0.0881 0.158 0.1887
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.012 0.0172 0.0172
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica serine/threonine kinase, putative 0.0062 0.0064 0.0088
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0084 0.0105 0.0359
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.014 0.0584
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0062 0.0064 0.0064
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0062 0.0064 0.0077
Echinococcus granulosus aurora kinase A 0.0084 0.0105 0.0126
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.5434 1 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0006
Brugia malayi serine/threonine protein kinase 6 0.0084 0.0105 0.0105
Echinococcus multilocularis G protein coupled receptor kinase 1 0.3284 0.6024 0.7197
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Onchocerca volvulus 0.0081 0.01 0.0569
Loa Loa (eye worm) protein kinase domain-containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0081 0.01 0.0321
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis protein kinase 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Onchocerca volvulus 0.0062 0.0064 0.0365
Brugia malayi serine/threonine kinase 12 0.0084 0.0105 0.0105
Trichomonas vaginalis kinesin light chain, putative 0.0081 0.01 0.0606
Echinococcus multilocularis Pleckstrin y 0.0081 0.01 0.0119
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Brugia malayi Cadps2 protein 0.0081 0.01 0.01
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0062 0.0064 0.4546
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0024 0.0125
Entamoeba histolytica cell surface protease gp63, putative 0.0181 0.0285 0.1535
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis heat shock protein 70 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0083 0.0104 0.6745
Echinococcus multilocularis Pleckstrin y 0.0081 0.01 0.0119
Onchocerca volvulus 0.0081 0.01 0.0569
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0062 0.0064 0.3087
Onchocerca volvulus 0.0081 0.01 0.0569
Loa Loa (eye worm) TK/DDR protein kinase 0.0062 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0062 0.0064 0.0077
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Echinococcus granulosus cytohesin 1 0.0081 0.01 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.003 0.0163
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0105 0.0642
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Echinococcus granulosus Pleckstrin y 0.0081 0.01 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0081 0.01 0.0321
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0062 0.0064 0.0379
Echinococcus granulosus semaphorin 1A 0.0414 0.0715 0.0854
Schistosoma mansoni hypothetical protein 0.0414 0.0715 0.0715
Echinococcus granulosus Oxysterol binding protein 11 0.0081 0.01 0.0119
Loa Loa (eye worm) hypothetical protein 0.0881 0.158 0.158
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Brugia malayi hypothetical protein 0.003 0.0006 0.0006
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0081 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase HCK 0.0062 0.0064 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.5434 1 1
Entamoeba histolytica ankyrin repeat protein 0.0062 0.0064 0.0088
Echinococcus granulosus beta 1 syntrophin 0.0081 0.01 0.0119
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Onchocerca volvulus 0.0062 0.0064 0.0365
Echinococcus multilocularis tyrosine protein kinase csk 0.0062 0.0064 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni fibrocystin l 0.0181 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Echinococcus multilocularis tyrosine protein kinase Abl 0.0062 0.0064 0.0077
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0105 0.0642
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0103 0.014 1
Echinococcus multilocularis expressed conserved protein 0.0027 0.0001 0.0001
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0081 0.01 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Echinococcus granulosus tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Echinococcus multilocularis tyrosine protein kinase pr2 0.0062 0.0064 0.0077
Echinococcus granulosus cGMP dependent protein kinase 1 0.0027 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Brugia malayi PXA domain containing protein 0.0881 0.158 0.158
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0081 0.01 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0051 0.0294
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Echinococcus multilocularis c src tyrosine kinase 0.0062 0.0064 0.0077
Plasmodium falciparum tyrosine kinase-like protein 0.0062 0.0064 0.4546
Entamoeba histolytica protein kinase domain containing protein 0.0084 0.0105 0.0359
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0181 0.0285 0.0285
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Schistosoma mansoni myotubularin-related protein 0.0081 0.01 0.01
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Entamoeba histolytica hypothetical protein 0.0103 0.014 0.0584
Loa Loa (eye worm) hypothetical protein 0.0881 0.158 0.158
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Schistosoma mansoni regulator of G protein signaling 0.0881 0.158 0.158
Echinococcus multilocularis axis inhibition protein axin 0.0881 0.158 0.1887
Loa Loa (eye worm) AGC/PKG protein kinase 0.0027 0.0001 0.0001
Echinococcus multilocularis regulator of G protein signaling 7 0.0881 0.158 0.1887
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0115 0.0163 0.0194
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) plexin A 0.1157 0.209 0.209
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0181 0.0285 0.0285
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0081 0.01 0.01
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0062 0.0064 0.0077
Echinococcus multilocularis ephrin type A receptor 4 A 0.0062 0.0064 0.0077
Trypanosoma cruzi Protein kinase B 0.0103 0.014 1
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0081 0.01 0.01
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Schistosoma mansoni z-protein (S1r protein) 0.0881 0.158 0.158
Schistosoma mansoni plexin 0.0562 0.099 0.099
Trypanosoma brucei PH domain containing protein, putative 0.0081 0.01 0.6342
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis beta adrenergic receptor kinase 0.4165 0.7654 0.9143
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0103 0.014 1
Brugia malayi Sema domain containing protein 0.0414 0.0715 0.0715
Echinococcus granulosus roundabout 2 0.012 0.0172 0.0206
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Entamoeba histolytica hypothetical protein 0.0181 0.0285 0.1535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0037
Entamoeba histolytica ankyrin repeat protein 0.0062 0.0064 0.0088
Echinococcus granulosus axis inhibition protein axin 0.0881 0.158 0.1887
Loa Loa (eye worm) hypothetical protein 0.0562 0.099 0.099
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0051 0.0051
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0062 0.0064 0.0077
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase 0.0062 0.0064 0.0077
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0081 0.01 0.7114
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0103 0.014 1
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Echinococcus granulosus neuroglian 0.0115 0.0163 0.0194
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0062 0.0064 0.0088
Echinococcus granulosus tyrosine protein kinase Blk 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Trypanosoma cruzi PH domain containing protein, putative 0.0081 0.01 0.6342
Schistosoma mansoni hypothetical protein 0.0181 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0062 0.0064 0.0077
Echinococcus multilocularis axis inhibition protein axin 0.0881 0.158 0.1887
Trichomonas vaginalis centaurin beta, putative 0.0081 0.01 0.0606
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0103 0.014 0.086
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0062 0.0064 0.0064
Echinococcus granulosus pdz domain containing protein 0.0081 0.01 0.0119
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0062 0.0064 0.0088
Echinococcus granulosus G protein coupled receptor kinase 1 0.3284 0.6024 0.7197
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0019
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Echinococcus multilocularis epidermal growth factor receptor 0.0062 0.0064 0.0077
Trypanosoma brucei Flagellum attachment zone protein 20 0.0062 0.0064 0.3087
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0062 0.0064 0.0077
Brugia malayi hypothetical protein 0.012 0.0172 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0881 0.158 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0024 0.0125
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) hypothetical protein 0.0881 0.158 0.158
Echinococcus multilocularis neuroglian 0.0115 0.0163 0.0194
Onchocerca volvulus outspread protein homolog 0.0081 0.01 0.0569
Onchocerca volvulus 0.0062 0.0064 0.0365
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0081 0.01 0.0119
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Giardia lamblia Kinase, NEK 0.0062 0.0064 0.2448
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi hypothetical protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.4553 0.8371 0.8371
Giardia lamblia Protein 21.1 0.0062 0.0064 0.2448
Onchocerca volvulus 0.0062 0.0064 0.0365
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.4553 0.8371 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0081 0.01 0.0606
Echinococcus granulosus tyrosine kinase 0.0062 0.0064 0.0077
Echinococcus granulosus transcription factor collier 0.0181 0.0285 0.0341
Schistosoma mansoni rho gtpase activating protein 0.0081 0.01 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0881 0.158 1
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica serine/threonine kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Schistosoma mansoni regulator of G protein signaling 0.0881 0.158 0.158
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0081 0.01 0.0321
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0083 0.0104 0.6745
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0976 0.1755 1
Loa Loa (eye worm) hypothetical protein 0.0881 0.158 0.158
Echinococcus granulosus fibroblast growth factor receptor 4 0.0062 0.0064 0.0077
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0881 0.158 1
Loa Loa (eye worm) hypothetical protein 0.0414 0.0715 0.0715
Echinococcus multilocularis oxysterol binding protein 1 0.0081 0.01 0.0119
Trichomonas vaginalis protein transport protein sec7, putative 0.0081 0.01 0.0606
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Plasmodium vivax PH domain containing protein 0.0081 0.01 0.4708
Brugia malayi Variant SH3 domain containing protein 0.0081 0.01 0.01
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.014 0.0584
Echinococcus granulosus plexin a4 0.1157 0.209 0.2497
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0081 0.01 0.0119
Brugia malayi Regulator of G protein signaling domain containing protein 0.0881 0.158 0.158
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis regulator of G protein signaling 3 0.0881 0.158 0.1887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0004 0.0001
Echinococcus granulosus tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0004 0.0001
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0062 0.0064 0.0064
Brugia malayi Raf kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Echinococcus granulosus axis inhibition protein axin 0.0881 0.158 0.1887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0037
Schistosoma mansoni semaphorin 5-related 0.0414 0.0715 0.0715
Entamoeba histolytica hypothetical protein 0.0081 0.01 0.0321
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0062 0.0064 0.0077
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0103 0.014 1
Echinococcus granulosus c src tyrosine kinase 0.0062 0.0064 0.0077
Brugia malayi Fibronectin type III domain containing protein 0.012 0.0172 0.0172
Loa Loa (eye worm) TK/EPH protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Schistosoma mansoni protein kinase 0.0083 0.0104 0.0104
Echinococcus multilocularis oxysterol binding protein 3 0.0081 0.01 0.0119
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0006
Echinococcus granulosus epidermal growth factor receptor 0.0062 0.0064 0.0077
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis kinase suppressor of Ras 1 0.0062 0.0064 0.0077
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis protein tyrosine kinase, putative 0.0062 0.0064 0.0379
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0067 0.0074 0.0088
Leishmania major hypothetical protein, conserved 0.0062 0.0064 0.4546
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trypanosoma brucei Pseudokinase, putative 0.0062 0.0064 0.3087
Brugia malayi PH domain containing protein 0.0081 0.01 0.01
Echinococcus multilocularis G protein coupled receptor kinase 6 0.4553 0.8371 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0062 0.0064 0.0077
Echinococcus multilocularis semaphorin 5B 0.0414 0.0715 0.0854
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0081 0.01 0.01
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0081 0.01 0.6342
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0103 0.014 1
Entamoeba histolytica hypothetical protein 0.0881 0.158 1
Schistosoma mansoni hypothetical protein 0.0081 0.01 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0062 0.0064 0.0064
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0062 0.0064 0.0077
Echinococcus multilocularis transfer RNA-Thr 0.0062 0.0064 0.0077
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0881 0.158 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.0163 0.0163
Echinococcus granulosus retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Entamoeba histolytica PH domain containing protein 0.0081 0.01 0.0321
Toxoplasma gondii STE kinase 0.0062 0.0064 0.4546
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Toxoplasma gondii hypothetical protein 0.0081 0.01 0.7114
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Entamoeba histolytica receptor protein kinase, putative 0.0062 0.0064 0.0088
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0081 0.01 0.0569
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0081 0.01 0.0321
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0062 0.0064 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0881 0.158 1
Schistosoma mansoni regulator of G protein signaling 0.0881 0.158 0.158
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.4553 0.8371 0.8371
Entamoeba histolytica PH domain containing protein kinase, putative 0.0103 0.014 0.0584
Echinococcus multilocularis insulin receptor 0.0062 0.0064 0.0077
Echinococcus granulosus cGMP dependent protein kinase 0.0027 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0081 0.01 0.7114
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Echinococcus granulosus regulator of G protein signaling 7 0.0881 0.158 0.1887
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0084 0.0105 0.0126
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.4165 0.7654 0.7654
Loa Loa (eye worm) hypothetical protein 0.0881 0.158 0.158
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0081 0.01 0.0321
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0029 0.0035
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0081 0.01 0.0119
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Echinococcus granulosus Pleckstrin y 0.0081 0.01 0.0119
Echinococcus granulosus cGMP dependent protein kinase 1 0.0027 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Entamoeba histolytica protein kinase, putative 0.0103 0.014 0.0584
Echinococcus granulosus Immunoglobulin 0.0115 0.0163 0.0194
Brugia malayi integrin-linked kinase 0.0062 0.0064 0.0064
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0881 0.158 0.1887
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0181 0.0285 0.1784
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0064 0.0379
Loa Loa (eye worm) hypothetical protein 0.0181 0.0285 0.0285
Loa Loa (eye worm) uncoordinated protein 104 0.0081 0.01 0.01
Trypanosoma cruzi aurora B kinase, putative 0.0084 0.0105 0.6861
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Entamoeba histolytica tyrosin kinase, putative 0.0062 0.0064 0.0088
Schistosoma mansoni protein kinase 0.0084 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.0285 0.1784
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trypanosoma cruzi PH domain containing protein, putative 0.0081 0.01 0.6342
Onchocerca volvulus 0.0062 0.0064 0.0365
Entamoeba histolytica tyrosin kinase, putative 0.0243 0.0399 0.2279
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) hypothetical protein 0.0181 0.0285 0.0285
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0062 0.0064 0.0077
Echinococcus multilocularis cytohesin 1 0.0081 0.01 0.0119
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0081 0.01 0.01
Brugia malayi hypothetical protein 0.0414 0.0715 0.0715
Schistosoma mansoni regulator of G protein signaling 0.0881 0.158 0.158
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.0051 0.1864
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis STE family protein kinase 0.0062 0.0064 0.0379
Onchocerca volvulus 0.003 0.0006 0.0034
Loa Loa (eye worm) syntrophin-1 0.0081 0.01 0.01
Entamoeba histolytica serine/threonine kinase, putative 0.0062 0.0064 0.0088
Brugia malayi Furin-like cysteine rich region family protein 0.0062 0.0064 0.0064
Echinococcus multilocularis beta 1 syntrophin 0.0081 0.01 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0103 0.014 1
Loa Loa (eye worm) sema domain-containing protein 0.0414 0.0715 0.0715
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Brugia malayi Oxysterol binding protein 0.0081 0.01 0.01
Entamoeba histolytica p21-activated kinase 0.0103 0.014 0.0584
Echinococcus multilocularis FL cytokine receptor 0.0062 0.0064 0.0077
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Echinococcus multilocularis tyrosine protein kinase Blk 0.0062 0.0064 0.0077
Loa Loa (eye worm) oxysterol binding protein 0.0081 0.01 0.01
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0103 0.014 1
Schistosoma mansoni dynamin 0.0081 0.01 0.01
Loa Loa (eye worm) RGS-3 protein 0.0881 0.158 0.158
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Echinococcus granulosus twitchin 0.0137 0.0203 0.0242
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0062 0.0064 0.0365
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0001 0.0001
Echinococcus granulosus oxysterol binding protein 1 0.0081 0.01 0.0119
Plasmodium falciparum tyrosine kinase-like protein 0.0062 0.0064 0.4546
Schistosoma mansoni serine/threonine-protein kinase 0.0103 0.014 0.014
Echinococcus multilocularis myotubularin protein 13 0.0081 0.01 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Leishmania major protein kinase, putative 0.0103 0.014 1
Loa Loa (eye worm) hypothetical protein 0.0414 0.0715 0.0715
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0064 0.0088
Schistosoma mansoni syntrophin 0.0081 0.01 0.01
Echinococcus multilocularis oxysterol binding protein 9 0.0081 0.01 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Brugia malayi hypothetical protein 0.0081 0.01 0.01
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica receptor protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0006
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0062 0.0064 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Entamoeba histolytica hypothetical protein 0.0181 0.0285 0.1535
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0062 0.0064 0.0064
Echinococcus multilocularis hypothetical protein 0.0414 0.0715 0.0854
Echinococcus multilocularis regulator of G protein signaling 0.0881 0.158 0.1887
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0881 0.158 0.158
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0181 0.0285 0.1784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0033
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0062 0.0064 0.0088
Loa Loa (eye worm) Plekhf2 protein 0.0081 0.01 0.01
Echinococcus multilocularis protein kinase 0.0062 0.0064 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0081 0.01 0.01
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0081 0.01 0.0119
Echinococcus granulosus tyrosine protein kinase Lyn 0.0083 0.0104 0.0125
Brugia malayi Sema domain containing protein 0.0414 0.0715 0.0715
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) RGC/RGC protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus tyrosine protein kinase csk 0.0062 0.0064 0.0077
Schistosoma mansoni oxysterol-binding protein 1 0.0081 0.01 0.01
Loa Loa (eye worm) TK/INSR protein kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Giardia lamblia Kinase 0.0062 0.0064 0.2448
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Brugia malayi Uncoordinated protein 104 0.0081 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trypanosoma brucei protein kinase, putative 0.0103 0.014 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0081 0.01 0.0321
Brugia malayi hypothetical protein 0.0062 0.0064 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0105 0.0105
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0084 0.0105 0.0359
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Leishmania major protein kinase, putative 0.0103 0.014 1
Brugia malayi Dynamin 0.0081 0.01 0.01
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0062 0.0064 0.0077
Entamoeba histolytica hypothetical protein, conserved 0.0081 0.01 0.0321
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0062 0.0064 0.0077
Leishmania major hypothetical protein, conserved 0.0081 0.01 0.7114
Brugia malayi Tyrosine-protein kinase abl-1 0.0062 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0018 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica PH domain containing protein 0.0081 0.01 0.0321
Brugia malayi Dynamin 0.0081 0.01 0.01
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0081 0.01 0.0321
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Echinococcus multilocularis MAM 0.003 0.0006 0.0007
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Entamoeba histolytica serine/threonine kinase, putative 0.0062 0.0064 0.0088
Echinococcus granulosus insulin receptor 0.0062 0.0064 0.0077
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Trypanosoma cruzi hypothetical protein 0.0081 0.01 0.6342
Schistosoma mansoni protein kinase 0.0083 0.0104 0.0104
Trypanosoma cruzi protein kinase, putative 0.0062 0.0064 0.3087
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0062 0.0064 0.0064
Echinococcus multilocularis Immunoglobulin 0.0115 0.0163 0.0194
Echinococcus multilocularis raf serine:threonine protein kinase 0.0062 0.0064 0.0077
Brugia malayi regulator of G-protein signaling egl-10 0.0881 0.158 0.158
Entamoeba histolytica tyrosin kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0414 0.0715 0.0715
Toxoplasma gondii protein kinase domain-containing protein 0.0103 0.014 1
Entamoeba histolytica ARF GTPase activating protein, putative 0.0081 0.01 0.0321
Schistosoma mansoni tyrosine protein kinase 0.0062 0.0064 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Echinococcus granulosus tyrosine kinase 0.0062 0.0064 0.0077
Echinococcus multilocularis natriuretic peptide receptor 1 0.0062 0.0064 0.0077
Entamoeba histolytica hypothetical protein 0.0081 0.01 0.0321
Schistosoma mansoni hypothetical protein 0.0081 0.01 0.01
Toxoplasma gondii hypothetical protein 0.0081 0.01 0.7114
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0103 0.014 0.086
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0067 0.0074 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi SRC-1 0.0062 0.0064 0.0064
Echinococcus granulosus beta-adrenergic receptor kinase 0.4165 0.7654 0.9143
Toxoplasma gondii phosphatidylinositol transfer protein 0.0081 0.01 0.7114
Entamoeba histolytica tyrosine kinase, putative 0.0062 0.0064 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0025 0.013
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Schistosoma mansoni vesicular amine transporter 0.0118 0.0168 0.0168
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0062 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis actin binding protein anillin 0.0081 0.01 0.0119
Brugia malayi C-terminal src kinase protein 1 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Brugia malayi Immunoglobulin I-set domain containing protein 0.0176 0.0276 0.0276
Trichomonas vaginalis alpha chimerin, putative 0.0081 0.01 0.0606
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Loa Loa (eye worm) TK protein kinase 0.0062 0.0064 0.0064
Brugia malayi Pleckstrin Homology Domain 0.0081 0.01 0.01
Entamoeba histolytica hypothetical protein 0.0062 0.0064 0.0088
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0115 0.0163 0.0163
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0103 0.014 1
Echinococcus granulosus oxysterol binding protein 3 0.0081 0.01 0.0119
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis rac serine:threonine kinase 0.0103 0.014 0.0167
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0115 0.0163 0.0194
Entamoeba histolytica protein kinase, putative 0.0062 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0081 0.01 0.01
Echinococcus granulosus receptor type guanylyl cyclase 0.0062 0.0064 0.0077
Loa Loa (eye worm) TK/RYK protein kinase 0.0062 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0062 0.0064 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0081 0.01 0.0606
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0881 0.158 0.158
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.01 0.0606
Brugia malayi Protein kinase domain containing protein 0.0062 0.0064 0.0064
Echinococcus multilocularis exocyst complex component 2 0.0181 0.0285 0.0341
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.0051 0.3581
Trichomonas vaginalis AGC family protein kinase 0.0103 0.014 0.086
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Echinococcus granulosus tyrosine protein kinase ABL1 0.0062 0.0064 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.001 0.0033
Entamoeba histolytica cysteine surface protein, putative 0.0062 0.0064 0.0088
Brugia malayi hypothetical protein 0.0881 0.158 0.158
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0081 0.01 0.0119
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0064
Schistosoma mansoni tyrosine kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0081 0.01 0.0606
Loa Loa (eye worm) TK/FAK protein kinase 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0081 0.01 0.0569
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0172 0.0172
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0081 0.01 0.6342
Trichomonas vaginalis conserved hypothetical protein 0.0881 0.158 1
Entamoeba histolytica protein kinase, putative 0.0084 0.0105 0.0359
Entamoeba histolytica serine/threonine kinase, putative 0.0062 0.0064 0.0088
Schistosoma mansoni cell adhesion molecule 0.012 0.0172 0.0172
Trichomonas vaginalis centaurin/arf, putative 0.0081 0.01 0.0606
Giardia lamblia Kinase, NEK 0.0062 0.0064 0.2448
Loa Loa (eye worm) TK/FER protein kinase 0.0062 0.0064 0.0064
Schistosoma mansoni protein kinase 0.0062 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0062 0.0064 0.0379
Loa Loa (eye worm) PXA domain-containing protein 0.0881 0.158 0.158
Schistosoma mansoni growth factor receptor-bound protein 0.0081 0.01 0.01
Loa Loa (eye worm) SRC-1 0.0062 0.0064 0.0064

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 150 nM Inhibition of mTOR-dependent S6K phosphorylation at T389 residue in MEF cells ChEMBL. 21621413

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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