Detailed information for compound 1025715

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 608.814 | Formula: C41H44N4O
  • H donors: 2 H acceptors: 1 LogP: 7.64 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N(C1CCN(CC1)Cc1ccccc1)Cc1cccc(c1)c1ccc(cc1)CNCCc1ccccc1)Nc1ccccc1
  • InChi: 1S/C41H44N4O/c46-41(43-39-17-8-3-9-18-39)45(40-24-27-44(28-25-40)31-35-13-6-2-7-14-35)32-36-15-10-16-38(29-36)37-21-19-34(20-22-37)30-42-26-23-33-11-4-1-5-12-33/h1-22,29,40,42H,23-28,30-32H2,(H,43,46)
  • InChiKey: MRTBVKRQUYCGND-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0072 0.0182 0.1798
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0126 0.0427 0.2312
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0043 0.005 0.0088
Echinococcus granulosus lamin dm0 0.0059 0.0127 0.0127
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.2235 1 1
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0142 0.05 0.1101
Echinococcus granulosus poly adp ribose polymerase 2 0.0096 0.0291 0.0291
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0048 0.0073 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi Nuclear hormone receptor family member nhr-41 0.009 0.0266 0.0465
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0043 0.005 0.0071
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0096 0.0293 0.0762
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0046 0.0107
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0058 0.012 0.0602
Brugia malayi MBOAT family protein 0.0061 0.0132 0.023
Brugia malayi Heterochromatin protein 1 0.0072 0.0183 0.0319
Onchocerca volvulus Bile acid receptor homolog 0.009 0.0266 0.1329
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0866 0.3786 0.6616
Echinococcus granulosus intermediate filament protein 0.0059 0.0127 0.0127
Onchocerca volvulus 0.0043 0.005 0.0249
Brugia malayi hypothetical protein 0.0473 0.2003 0.35
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.005 0.005
Brugia malayi chromobox protein homolog 3 0.004 0.004 0.0069
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0198 0.0754 0.1318
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0043 0.005 0.005
Mycobacterium ulcerans hypothetical protein 0.0042 0.0046 0.0388
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0083 0.0232 0.0327
Mycobacterium ulcerans Type I modular polyketide synthase 0.0108 0.0348 0.352
Brugia malayi intermediate filament protein 0.0059 0.0127 0.0221
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0058 0.012 0.0602
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0122 0.0412 0.0412
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0126 0.0427 0.2631
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0866 0.3786 1
Mycobacterium ulcerans polyketide synthase Pks13 0.0162 0.0591 0.6033
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0162 0.0591 0.5547
Giardia lamblia GTOR 0.0198 0.0754 0.4104
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0058 0.012 0.0505
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.012 0.0516
Loa Loa (eye worm) phosphatidylinositol kinase 0.0058 0.012 0.0189
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0061 0.0132 0.0185
Echinococcus multilocularis chromobox protein 1 0.0072 0.0183 0.0183
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0096 0.0293 0.0762
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0491 0.0491
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.009 0.0266 0.0266
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0115 0.0378 0.3815
Schistosoma mansoni survival motor neuron protein 0.005 0.0083 0.0116
Brugia malayi Nuclear hormone receptor E75 0.0043 0.005 0.0088
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0058 0.0033
Brugia malayi MBOAT family protein 0.0061 0.0132 0.023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0208
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0074
Schistosoma mansoni thyroid hormone receptor 0.009 0.0266 0.0374
Loa Loa (eye worm) hypothetical protein 0.0122 0.0412 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi RNA recognition motif domain containing protein 0.0033 0.0008 0.0014
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0198 0.0754 0.2072
Leishmania major hypothetical protein, conserved 0.083 0.3623 1
Entamoeba histolytica hypothetical protein, conserved 0.0061 0.0132 0.0103
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.008 0.022 0.0467
Echinococcus multilocularis chromobox protein 1 0.0072 0.0183 0.0183
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1599 0.7114 0.7114
Onchocerca volvulus 0.0059 0.0127 0.063
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0174 0.0647 0.0647
Echinococcus multilocularis tar DNA binding protein 0.0033 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0312 0.1272 0.3191
Onchocerca volvulus 0.0059 0.0127 0.063
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0105 0.0333 0.3106
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0198 0.0754 0.572
Loa Loa (eye worm) hypothetical protein 0.0047 0.0072 0.0113
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0142 0.05 0.0703
Trypanosoma cruzi glycerol uptake protein, putative 0.0061 0.0132 0.0231
Mycobacterium tuberculosis Conserved protein 0.0042 0.0046 0.0384
Brugia malayi Nuclear hormone receptor family member nhr-19 0.009 0.0266 0.0465
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.012 0.0189
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0126 0.0427 0.2631
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0198 0.0754 0.2072
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0491 0.0858
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0096 0.0291 0.0656
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0055 0.0105 0.0412
Brugia malayi hypothetical protein 0.0052 0.0094 0.0164
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0147 0.0394
Echinococcus granulosus muscleblind protein 0.1293 0.5723 0.5723
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0147 0.1443
Loa Loa (eye worm) MBOAT family protein 0.0061 0.0132 0.0208
Echinococcus granulosus poly (ADP ribose) polymerase 0.0054 0.0102 0.0102
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0087 0.0252 0.2527
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0075 0.02 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0048 0.0073 0.0073
Giardia lamblia Fructose-bisphosphate aldolase 0.0267 0.1069 0.5827
Schistosoma mansoni hypothetical protein 0.0033 0.0005 0.0008
Toxoplasma gondii type I fatty acid synthase, putative 0.0077 0.0206 0.1113
Echinococcus multilocularis protein dispatched 1 0.0044 0.0057 0.0057
Brugia malayi nuclear hormone receptor 0.009 0.0266 0.0465
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0133 0.0463 0.2884
Schistosoma mansoni patched 1 0.0039 0.0032 0.0045
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.012 0.0516
Trichomonas vaginalis esterase, putative 0.0042 0.0046 0.0107
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0046 0.0384
Loa Loa (eye worm) phosphatidylinositol 3 0.0198 0.0754 0.119
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0052 0.0094 0.0132
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0061 0.0132 0.0208
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0058 0.012 0.0602
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.009 0.0266 0.042
Schistosoma mansoni hypothetical protein 0.005 0.0083 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0063 0.0142 0.0223
Trypanosoma brucei glycerol uptake protein, putative 0.0061 0.0132 0.0696
Mycobacterium ulcerans Type I modular polyketide synthase 0.0108 0.0348 0.352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0133 0.0463 0.121
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.012 0.0516
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0101 0.0316 0.2943
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0147 0.0207
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.009 0.0266 0.0374
Schistosoma mansoni chromobox protein 0.0072 0.0183 0.0257
Giardia lamblia Phosphatidylinositol 4-kinase 0.0058 0.012 0.063
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0205 0.0787 0.1376
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0046 0.0107
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0072
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0605 0.2603 0.6871
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0246 0.0974 0.2482
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0312 0.1272 0.3191
Echinococcus multilocularis 0.0058 0.012 0.012
Brugia malayi hypothetical protein 0.0094 0.0285 0.0498
Toxoplasma gondii FATC domain-containing protein 0.0138 0.0483 0.3026
Mycobacterium leprae Probable lipase LipE 0.0042 0.0046 0.0356
Brugia malayi WGR domain containing protein 0.0096 0.0291 0.0508
Schistosoma mansoni hypothetical protein 0.0375 0.156 0.2193
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0142 0.05 0.0874
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.036 0.1492 0.1492
Echinococcus multilocularis sterol regulatory element binding protein 0.0039 0.0032 0.0032
Brugia malayi nuclear receptor NHR-67 0.0043 0.005 0.0088
Onchocerca volvulus 0.0174 0.0648 0.3234
Schistosoma mansoni peptidase Clp (S14 family) 0.0042 0.0047 0.0066
Brugia malayi Nuclear hormone receptor E75 0.0043 0.005 0.0088
Brugia malayi MH2 domain containing protein 0.0063 0.0142 0.0247
Echinococcus multilocularis Zinc finger, PHD finger 0.0142 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Echinococcus granulosus lamin 0.0059 0.0127 0.0127
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.009 0.0265 0.0465
Plasmodium vivax hypothetical protein, conserved 0.0058 0.012 0.0516
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0138 0.0483 0.0679
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.009 0.0266 0.042
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0142 0.05 0.3138
Loa Loa (eye worm) transcription factor SMAD2 0.0063 0.0142 0.0223
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0061 0.0132 0.0103
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0061 0.0132 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.009 0.0266 0.042
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0058 0.012 0.0169
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0008 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0043 0.005 0.0071
Echinococcus granulosus ecdysone induced protein 78C 0.009 0.0266 0.0266
Brugia malayi nuclear receptor RXR 0.0048 0.0073 0.0128
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0246 0.0974 0.642
Schistosoma mansoni thyroid hormone receptor 0.009 0.0266 0.0374
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0061 0.0132 0.0132
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0572 0.2455 0.2455
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0092
Plasmodium vivax hypothetical protein 0.0058 0.012 0.0516
Echinococcus granulosus retinoic acid receptor rxr beta a 0.009 0.0266 0.0266
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0142 0.05 0.05
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0061 0.0132 0.0132
Onchocerca volvulus 0.0101 0.0316 0.1575
Echinococcus multilocularis sterol O acyltransferase 1 0.0061 0.0132 0.0132
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.005 0.005
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0058 0.01
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0198 0.0754 0.1789
Echinococcus granulosus Niemann Pick C1 protein 0.0129 0.0441 0.0441
Brugia malayi TAR-binding protein 0.0033 0.0008 0.0014
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0198 0.0754 0.0754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0149 0.0381
Loa Loa (eye worm) hypothetical protein 0.1293 0.5723 0.9024
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0054 0.0266
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.0266 0.0266
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0042 0.0047 0.5
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0061 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0094 0.0285 0.045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.009 0.0266 0.042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0061 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0208
Brugia malayi conserved hypotetical protein 0.0043 0.005 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0126 0.0427 0.264
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0115 0.0378 0.3537
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0198 0.0754 0.1789
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0491 0.0691
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Loa Loa (eye worm) hypothetical protein 0.008 0.022 0.0347
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.013 0.0449 0.4207
Schistosoma mansoni lamin 0.0059 0.0127 0.0178
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0312 0.1272 0.3279
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0046 0.0388
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0315 0.1285 0.3313
Brugia malayi RNA binding protein 0.0033 0.0008 0.0014
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0005 0.0009
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0254 0.1009 0.2576
Schistosoma mansoni hypothetical protein 0.0033 0.0005 0.0008
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1599 0.7114 0.7114
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.012 0.0304
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0058 0.012 0.0199
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0267 0.1069 0.2642
Brugia malayi nuclear receptor NHR-88 0.009 0.0266 0.0465
Schistosoma mansoni hypothetical protein 0.0037 0.0026 0.0037
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0096 0.0293 0.0293
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0326 0.0569
Brugia malayi steroid hormone receptor 0.0166 0.0611 0.1067
Mycobacterium ulcerans polyketide synthase Pks9 0.0072 0.0182 0.1798
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0122 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Mycobacterium leprae Polyketide synthase Pks13 0.0162 0.0591 0.602
Loa Loa (eye worm) MBOAT family protein 0.0061 0.0132 0.0208
Echinococcus multilocularis FTZ F1 alpha 0.009 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0033 0.0005 0.0008
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0142 0.05 0.05
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0096 0.0293 0.0762
Toxoplasma gondii preprocathepsin c precursor, putative 0.0126 0.0427 0.264
Echinococcus multilocularis microtubule associated protein 2 0.1 0.4396 0.4396
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0246 0.0974 0.2482
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0198 0.0754 0.0754
Toxoplasma gondii target of rapamycin (TOR), putative 0.0198 0.0754 0.4903
Loa Loa (eye worm) hypothetical protein 0.0133 0.0463 0.0729
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0198 0.0754 0.1895
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0046 0.0384
Trichomonas vaginalis transmembrane protein nessy, putative 0.0061 0.0132 0.0335
Loa Loa (eye worm) hypothetical protein 0.0059 0.0127 0.0199
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0058 0.012 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0463 0.121
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0402 0.1684 0.4306
Loa Loa (eye worm) hypothetical protein 0.0174 0.0648 0.1022
Mycobacterium tuberculosis Probable thioesterase TesA 0.009 0.0266 0.2473
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.009 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.0051
Loa Loa (eye worm) hypothetical protein 0.0473 0.2003 0.3158
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.009 0.0266 0.0465
Schistosoma mansoni dihydroorotate dehydrogenase 0.0246 0.0974 0.1369
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0061 0.0132 0.0132
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0866 0.3786 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.009 0.0266 0.042
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0133 0.0463 0.3365
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0042 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Loa Loa (eye worm) acyl carrier protein 0.005 0.0083 0.0131
Trypanosoma cruzi glycerol uptake protein, putative 0.0061 0.0132 0.0231
Leishmania major phosphatidylinositol 3-kinase, putative 0.0198 0.0754 0.2072
Echinococcus multilocularis expressed conserved protein 0.0085 0.0241 0.0241
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0061 0.0132 0.0185
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0046 0.008
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0198 0.0754 0.0754
Schistosoma mansoni zinc finger protein 0.0043 0.005 0.0071
Echinococcus granulosus poly ADP ribose polymerase 1 0.0174 0.0647 0.0647
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0091 0.0272 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0132 0.0335
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0046 0.0388
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0198 0.0754 0.1895
Echinococcus granulosus geminin 0.0375 0.156 0.156
Entamoeba histolytica hypothetical protein 0.0696 0.3015 0.791
Loa Loa (eye worm) hypothetical protein 0.0244 0.0963 0.1518
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Brugia malayi nuclear hormone receptor 0.0043 0.005 0.0088
Loa Loa (eye worm) beta-lactamase 0.0042 0.0046 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0866 0.3786 1
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0142 0.05 0.131
Schistosoma mansoni hypothetical protein 0.0037 0.0026 0.0037
Mycobacterium ulcerans polyketide synthase 0.0108 0.0348 0.352
Leishmania major glycerol uptake protein, putative 0.0061 0.0132 0.0351
Entamoeba histolytica hypothetical protein 0.0138 0.0483 0.1055
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0008 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0061 0.0132 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0228 0.0892 0.4855
Leishmania major phosphatidylinositol 4-kinase, putative 0.0058 0.012 0.0318
Loa Loa (eye worm) fatty acid synthase 0.0107 0.0341 0.0538
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0042 0.0047 0.5
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0326 0.0569
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.0266 0.0266
Brugia malayi hypothetical protein 0.0043 0.005 0.0088
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.009 0.0266 0.2648
Echinococcus multilocularis ecdysone induced protein 78C 0.009 0.0266 0.0266
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0096 0.0293 0.0762
Mycobacterium ulcerans fatty acid synthase Fas 0.0034 0.0011 0.0034
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0122 0.0412 0.098
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.036 0.1492 1
Trypanosoma cruzi GUP1, putative 0.0061 0.0132 0.0231
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.004 0.0197
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.005 0.005
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0198 0.0754 0.572
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.007 0.0176 0.0899
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.012 0.012
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0312 0.1272 0.9896
Echinococcus multilocularis muscleblind protein 0.1293 0.5723 0.5723
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0198 0.0754 0.1895
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.0963 0.0963
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0102 0.015
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0061 0.0132 0.0103
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Brugia malayi FAT domain containing protein 0.0075 0.02 0.0349
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.009 0.0266 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.009 0.0266 0.042
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.0063
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0116
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0138 0.0483 0.3531
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0142 0.05 0.3146
Toxoplasma gondii cathepsin CPC2 0.0048 0.0073 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.009 0.0266 0.0465
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0101 0.0316 0.0498
Onchocerca volvulus 0.009 0.0266 0.1329
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0042 0.0047 0.0011
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0046 0.0384
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0069 0.0168 0.0265
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.012 0.0189
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.009 0.0266 0.0266
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0491 0.0491
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0048 0.0073 0.0073
Toxoplasma gondii hypothetical protein 0.0061 0.0132 0.0597
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0043 0.005 0.0071
Onchocerca volvulus 0.0042 0.0046 0.0226
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0061 0.0132 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-19 0.009 0.0266 0.0465
Loa Loa (eye worm) hypothetical protein 0.0096 0.0291 0.0459
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0042 0.0047 0.0047
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0127 0.0221
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0087 0.0252 0.2501
Echinococcus multilocularis Niemann Pick C1 protein 0.009 0.0265 0.0265
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.009 0.0266 0.0374
Loa Loa (eye worm) hhat protein 0.0061 0.0132 0.0208
Brugia malayi Muscleblind-like protein 0.1293 0.5723 1
Echinococcus granulosus tar DNA binding protein 0.0033 0.0008 0.0008
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0105 0.0333 0.3106
Loa Loa (eye worm) hypothetical protein 0.0182 0.0682 0.1075
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0096 0.0293 0.0762
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0132 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0149 0.0381
Brugia malayi Nuclear hormone receptor family member nhr-31 0.009 0.0266 0.0465
Echinococcus multilocularis serine protein kinase ATM 0.0138 0.0483 0.0483
Echinococcus granulosus Niemann Pick C1 protein 0.009 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0042 0.0047 0.0011
Brugia malayi beta-lactamase family protein 0.0042 0.0046 0.008
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0037 0.0026 0.0198
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0208
Schistosoma mansoni microtubule-associated protein tau 0.1 0.4396 0.618
Brugia malayi Hhat protein 0.0061 0.0132 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0147 0.0705
Loa Loa (eye worm) hhat protein 0.0061 0.0132 0.0208
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0073 0.0103
Brugia malayi MBOAT family protein 0.0061 0.0132 0.023
Schistosoma mansoni nuclear receptor nhr-48 0.0043 0.005 0.0071
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0696 0.3015 0.791
Leishmania major phosphatidylinositol kinase related protein, putative 0.0074 0.0191 0.0515
Loa Loa (eye worm) hypothetical protein 0.0058 0.012 0.0189
Echinococcus granulosus thyroid hormone receptor alpha 0.0118 0.0394 0.0394
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0115 0.0378 0.3815
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0142 0.05 0.05
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.0266 0.0266
Schistosoma mansoni methyltransferase-related 0.0033 0.0005 0.0007
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0058 0.012 0.0169
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.005 0.0249
Loa Loa (eye worm) hypothetical protein 0.0473 0.2003 0.3158
Schistosoma mansoni lozenge 0.0059 0.0126 0.0178
Loa Loa (eye worm) diacylglycerol acyltransferase 0.036 0.1492 0.2352
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0039 0.0032 0.0051
Leishmania major hypothetical protein, conserved 0.0061 0.0132 0.0351
Echinococcus granulosus nuclear receptor nhr 48 0.0043 0.005 0.005
Plasmodium falciparum diacylglycerol O-acyltransferase 0.036 0.1492 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Loa Loa (eye worm) DR-78 0.0043 0.005 0.0079
Schistosoma mansoni hypothetical protein 0.0037 0.0026 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0092
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.009 0.0266 0.0266
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0246 0.0974 0.749
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0061 0.0132 0.0132
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0073 0.0128
Leishmania major glycerol uptake protein, putative 0.0061 0.0132 0.0351
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0088 0.0258 0.2401
Schistosoma mansoni zinc finger protein 0.0061 0.0132 0.0185
Onchocerca volvulus Huntingtin homolog 0.0094 0.0285 0.1423
Toxoplasma gondii cathepsin CPC1 0.0126 0.0427 0.264
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0115 0.0378 0.3537
Schistosoma mansoni hypothetical protein 0.0075 0.02 0.0281
Onchocerca volvulus 0.0042 0.0046 0.0226
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi hypothetical protein 0.0048 0.0073 0.0128
Brugia malayi hypothetical protein 0.0043 0.005 0.0088
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0147 0.0147
Brugia malayi photoreceptor-specific nuclear receptor 0.009 0.0266 0.0465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0491 0.0691
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0061 0.0132 0.0132
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.009 0.0266 0.0266
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.012 0.0189
Leishmania major mitochondrial DNA polymerase beta 0.0315 0.1285 0.3538
Onchocerca volvulus 0.0042 0.0046 0.0226
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0061 0.0132 0.0185
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0312 0.1272 0.2223
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0058 0.012 0.0199
Echinococcus granulosus sterol O acyltransferase 1 0.0061 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0116
Trypanosoma cruzi hypothetical protein, conserved 0.0772 0.336 0.8859
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.012 0.021
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0052 0.0094 0.0094
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.036 0.1492 0.1492
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.036 0.1492 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0198 0.0754 0.1061
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0246 0.0974 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0254 0.1009 0.1591
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0198 0.0754 0.2072
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0138 0.0483 0.117
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0054 0.0129
Mycobacterium ulcerans polyketide synthase 0.0115 0.0378 0.3836
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0142 0.05 0.3146
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.012 0.0189
Brugia malayi ecdysone receptor 0.0043 0.005 0.0088
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0108 0.0348 0.3498
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.012 0.012
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0142 0.05 0.131
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.009 0.0266 0.0266
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0058 0.0033
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0061 0.0132 0.0185
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0866 0.3786 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0198 0.0754 0.1895
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0108 0.0348 0.3248
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0058 0.012 0.0304
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0183 0.047
Brugia malayi orphan nuclear receptor NR2E1 0.0043 0.005 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Brugia malayi Methyltransferase-like protein 4 0.0033 0.0005 0.0009
Brugia malayi diacylglycerol acyltransferase 0.036 0.1492 0.2606
Brugia malayi Nuclear hormone receptor family member nhr-40 0.009 0.0266 0.0465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.019 0.0719 0.4655
Echinococcus multilocularis poly (ADP ribose) polymerase 0.004 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0058 0.0122 0.0192
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0198 0.0754 0.572
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Echinococcus multilocularis geminin 0.0375 0.156 0.156
Toxoplasma gondii type I fatty acid synthase, putative 0.0115 0.0378 0.2302
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0265 0.1061 1
Mycobacterium ulcerans lipase LipD 0.0042 0.0046 0.0388
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0142 0.05 0.131
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0061 0.0132 0.0132
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0042 0.0047 0.0405
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0005 0.0005
Leishmania major glycerol uptake protein, putative 0.0061 0.0132 0.0351
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0312 0.1272 0.3351
Brugia malayi MBOAT family protein 0.0061 0.0132 0.023
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0108 0.0348 0.3498
Brugia malayi WGR domain containing protein 0.0174 0.0647 0.113
Onchocerca volvulus 0.0473 0.2003 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0108 0.0348 0.3248
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0008 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.012 0.109
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0046 0.0107
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0315 0.1285 0.3313
Leishmania major glycerol uptake protein, putative 0.0061 0.0132 0.0351
Schistosoma mansoni nuclear receptor 0.0043 0.005 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0412 0.1076
Loa Loa (eye worm) hypothetical protein 0.0075 0.02 0.0315
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0005 0.0009
Schistosoma mansoni steroid hormone receptor ad4bp 0.009 0.0266 0.0374
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1599 0.7114 1
Echinococcus granulosus GPCR family 2 0.0033 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-14 0.009 0.0266 0.0465
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0046 0.0384
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0042 0.0047 0.0011
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0058 0.012 0.0199
Brugia malayi ecdysteroid receptor 0.009 0.0266 0.0465
Schistosoma mansoni retinoid-x-receptor (RXR) 0.009 0.0266 0.0374
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0246 0.0974 0.642
Leishmania major hypothetical protein, unknown function 0.0058 0.012 0.0318
Echinococcus multilocularis thyroid hormone receptor alpha 0.009 0.0266 0.0266
Giardia lamblia Hypothetical protein 0.0058 0.012 0.063
Schistosoma mansoni Tr4/Tr2 (homologue) 0.009 0.0266 0.0374
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0147 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0043 0.005 0.0079
Schistosoma mansoni fkbp-rapamycin associated protein 0.0122 0.0412 0.0579
Brugia malayi hypothetical protein 0.0048 0.0073 0.0128
Entamoeba histolytica hypothetical protein 0.0058 0.012 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0073 0.0128
Echinococcus multilocularis musashi 0.0059 0.0127 0.0127
Trypanosoma brucei poly(adp-ribose) polymerase 0.0096 0.0291 0.1981
Onchocerca volvulus 0.0188 0.0711 0.3551
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0046 0.0384
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0127 0.0199
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0046 0.0107
Schistosoma mansoni lamin 0.0059 0.0127 0.0178
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0058 0.012 0.0516
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0178 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0132 0.0335
Schistosoma mansoni nuclear hormone receptor 0.0043 0.005 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0483 0.1265
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0198 0.0754 0.0754
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0126 0.0427 0.264
Mycobacterium leprae conserved hypothetical protein 0.0058 0.012 0.113
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0048 0.0073 0.0375
Mycobacterium ulcerans thioesterase 0.009 0.0266 0.2673
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.009 0.0266 0.1329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Mycobacterium tuberculosis Conserved protein 0.0042 0.0046 0.0384
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0246 0.0974 0.1701
Brugia malayi Zinc finger, C2H2 type family protein 0.0096 0.0293 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0032 0.0072
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0058 0.012 0.012
Brugia malayi nuclear hormone receptor family member odr-7 0.0043 0.005 0.0088
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0533 0.1459
Loa Loa (eye worm) TAR-binding protein 0.0033 0.0008 0.0013
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0808 0.3523 0.9288
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0183 0.0288
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0072
Loa Loa (eye worm) steroid hormone receptor 0.0166 0.0611 0.0963
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0096 0.0293 0.0293
Trichomonas vaginalis porcupine, putative 0.0061 0.0132 0.0335
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0061 0.0136 0.1242
Loa Loa (eye worm) hypothetical protein 0.0157 0.057 0.0899
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0267 0.1069 0.2815
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0096 0.0293 0.0662
Loa Loa (eye worm) hypothetical protein 0.0293 0.1188 0.1873
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0108 0.0348 0.0608
Echinococcus granulosus Protein patched homolog 1 0.0039 0.0032 0.0032
Loa Loa (eye worm) runx1 0.0059 0.0126 0.0199
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0005 0.0005
Echinococcus multilocularis lamin dm0 0.0059 0.0127 0.0127
Leishmania major dihydroorotate dehydrogenase 0.0246 0.0974 0.2678
Mycobacterium tuberculosis Conserved protein 0.0042 0.0046 0.0384
Loa Loa (eye worm) hypothetical protein 0.1293 0.5723 0.9024
Entamoeba histolytica hypothetical protein 0.0058 0.012 0.0071
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0147 0.1443
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0048 0.0073 0.0182
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0147 0.1349
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0142 0.05 0.3146
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0572 0.2455 0.2455
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0572 0.2455 0.429
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0491 0.0491
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0001 0.0002
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0162 0.0591 0.5547
Echinococcus multilocularis Protein lozenge 0.0059 0.0126 0.0126
Brugia malayi beta-lactamase 0.0042 0.0046 0.008
Loa Loa (eye worm) hypothetical protein 0.0572 0.2455 0.3871
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0115 0.0378 0.3836
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0142 0.05 0.0789
Leishmania major hypothetical protein, conserved 0.0042 0.0046 0.0112
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.012 0.012
Brugia malayi MBOAT family protein 0.0061 0.0132 0.023
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0733 0.3185 0.5565
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0198 0.0754 0.572
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0198 0.0754 0.1895
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Echinococcus granulosus o acyltransferase membrane bound domain 0.0061 0.0132 0.0132
Trypanosoma cruzi glycerol uptake protein, putative 0.0061 0.0132 0.0231
Loa Loa (eye worm) hypothetical protein 0.009 0.0265 0.0418
Leishmania major phosphatidylinositol 3-kinase, putative 0.0142 0.05 0.1369
Onchocerca volvulus Huntingtin homolog 0.0094 0.0285 0.1423
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0142 0.05 0.1216
Leishmania major glycerol uptake protein, putative 0.0061 0.0132 0.0351
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0122 0.0412 0.072
Entamoeba histolytica protein kinase rad3, putative 0.0122 0.0412 0.0862
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.012 0.0304
Entamoeba histolytica hypothetical protein 0.0061 0.0132 0.0103
Brugia malayi CHE-14 protein 0.0039 0.0032 0.0056
Loa Loa (eye worm) hypothetical protein 0.03 0.1217 0.1919
Brugia malayi nuclear receptor NHR-88 0.0043 0.005 0.0088
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.005 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0046 0.0064
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.009 0.0266 0.0374
Loa Loa (eye worm) hypothetical protein 0.0033 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0132 0.0458 0.0723
Loa Loa (eye worm) nuclear hormone receptor 0.0043 0.005 0.0079
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0115 0.0378 0.3836
Schistosoma mansoni RAR-like nuclear receptor 0.009 0.0266 0.0374
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0052 0.0094 0.0094
Echinococcus granulosus sterol regulatory element binding protein 0.0039 0.0032 0.0032
Echinococcus multilocularis protein patched 0.0039 0.0032 0.0032
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0058 0.012 0.0071
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0122 0.0412 0.0862
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0267 0.1069 0.2642
Loa Loa (eye worm) nuclear receptor NHR-67 0.0043 0.005 0.0079
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.036 0.1492 0.2097
Onchocerca volvulus 0.0058 0.012 0.0598
Mycobacterium ulcerans beta-lactamase 0.0042 0.0046 0.0388
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0061 0.0132 0.0185
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0043 0.005 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0533 0.1303
Onchocerca volvulus Protein ultraspiracle homolog 0.009 0.0266 0.1329
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.012 0.021
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Trypanosoma brucei glycerol uptake protein, putative 0.0061 0.0132 0.0696
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.013 0.0449 0.455
Schistosoma mansoni hypothetical protein 0.0037 0.0026 0.0037
Echinococcus multilocularis nuclear receptor nhr 48 0.0043 0.005 0.005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0048 0.0073 0.0103
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0246 0.0974 0.9175
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0116
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0127 0.0199
Brugia malayi tailless protein 0.0043 0.005 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Schistosoma mansoni hypothetical protein 0.0071 0.0178 0.025
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0115 0.0378 0.3537
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0142 0.05 0.1369
Echinococcus multilocularis Niemann Pick C1 protein 0.0129 0.0441 0.0441
Entamoeba histolytica vacuolar protein sorting 26 0.0061 0.0132 0.0103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.005 0.005
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0605 0.2603 0.6871
Loa Loa (eye worm) RNA binding protein 0.0033 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0375 0.156 0.2193
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0072
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.036 0.1492 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0491 0.0775
Brugia malayi hypothetical protein 0.0244 0.0963 0.1682
Echinococcus granulosus o acyltransferase membrane bound domain 0.0061 0.0132 0.0132
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0096 0.0291 0.0656
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0046 0.0107
Schistosoma mansoni nuclear receptor 0.0043 0.005 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0246 0.0974 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi Nuclear hormone receptor family member nhr-25 0.009 0.0266 0.0465
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0046 0.0046
Echinococcus granulosus expressed conserved protein 0.0085 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0116
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0048 0.0073 0.0375
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0142 0.05 0.367
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0046 0.0384
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0198 0.0754 0.572
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.005 0.005
Loa Loa (eye worm) phosphatidylinositol 3 0.1429 0.6342 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0315 0.1285 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0198 0.0754 0.2072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0046 0.0064
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0075 0.02 0.02
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0054 0.0129
Schistosoma mansoni hypothetical protein 0.0058 0.012 0.0169
Echinococcus granulosus WGR domain containing protein 0.0054 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0071 0.0178 0.028
Onchocerca volvulus 0.0043 0.005 0.0249
Echinococcus multilocularis GPCR, family 2 0.0033 0.0005 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0052 0.0094 0.0132
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0072
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0087 0.0252 0.2527
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0096 0.0293 0.0762
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.0266 0.0266
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0246 0.0974 0.1701
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.005 0.0249
Echinococcus multilocularis lamin 0.0059 0.0127 0.0127
Mycobacterium ulcerans thioesterase TesA 0.009 0.0266 0.2673
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0043 0.005 0.005
Brugia malayi Niemann-Pick C1 protein precursor 0.009 0.0265 0.0464
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0008 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0101 0.0316 0.0552
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0312 0.1272 0.3351
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.009 0.0266 0.0465
Schistosoma mansoni intermediate filament proteins 0.0059 0.0127 0.0178
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0435 0.1831 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0058 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0078 0.0211 0.0545
Brugia malayi nuclear hormone receptor family member nhr-6 0.0043 0.005 0.0088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0491 0.0691
Loa Loa (eye worm) hypothetical protein 0.0103 0.0326 0.0514
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0048 0.0073 0.0193
Plasmodium falciparum dihydroorotate dehydrogenase 0.0246 0.0974 0.6416
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0147 0.0147
Treponema pallidum alginate O-acetylation protein (algI) 0.0061 0.0132 0.0828
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0074 0.0191 0.0389
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0044 0.0056 0.0479
Schistosoma mansoni coup transcription factor 0.009 0.0266 0.0374
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.009 0.0266 0.0266
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0033 0.0008 0.0013
Brugia malayi beta-lactamase family protein 0.0042 0.0046 0.008
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0183 0.047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0083 0.0144
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0312 0.1272 0.1788
Echinococcus granulosus o acyltransferase membrane bound domain 0.0061 0.0132 0.0132
Schistosoma mansoni tar DNA-binding protein 0.0033 0.0008 0.0011
Loa Loa (eye worm) phosphatidylinositol 3 0.0198 0.0754 0.119
Onchocerca volvulus 0.005 0.0083 0.0411
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0174 0.0647 0.0909
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.171 0.762 0.762
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0108 0.0348 0.3248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0116
Mycobacterium leprae Probable polyketide synthase Pks1 0.0115 0.0378 0.3815
Brugia malayi Steroid receptor seven-up type 2 0.009 0.0266 0.0465
Entamoeba histolytica hypothetical protein 0.0058 0.012 0.0071
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0126 0.0427 0.0601
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0096 0.0291 0.0409
Brugia malayi Nuclear hormone receptor family member nhr-1 0.009 0.0266 0.0465
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0078 0.021 0.1939
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.013 0.0449 0.4569
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0174 0.0647 0.1498
Echinococcus granulosus FTZ F1 alpha 0.009 0.0266 0.0266
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0072 0.0182 0.177
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0096 0.0291 0.0291
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0033 0.0008 0.0029
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0096 0.0293 0.054
Loa Loa (eye worm) MBOAT family protein 0.0061 0.0132 0.0208
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0079
Echinococcus granulosus chromobox protein 1 0.0072 0.0183 0.0183
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0198 0.0754 0.1061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0208
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0046 0.0072
Schistosoma mansoni retinoic acid receptor RXR 0.009 0.0266 0.0374
Schistosoma mansoni hypothetical protein 0.0033 0.0005 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0005 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-49 0.009 0.0266 0.0465
Leishmania major phosphatidylinositol kinase, putative 0.0058 0.012 0.0318
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0058 0.012 0.0169
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0058 0.0033
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0108 0.0348 0.352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Onchocerca volvulus 0.0061 0.0132 0.0657
Treponema pallidum fructose-bisphosphate aldolase 0.0267 0.1069 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0072
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0142 0.05 0.0703
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0142 0.05 0.1216
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0058 0.012 0.021
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0533 0.3932
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0312 0.1272 0.3351
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0147 0.1443
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.0963 0.0963
Mycobacterium ulcerans Type I modular polyketide synthase 0.0108 0.0348 0.352
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0046 0.0384
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0058 0.012 0.0199
Schistosoma mansoni sterol O-acyltransferase 1 0.0061 0.0132 0.0185
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0034 0.0011 0.006
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0046 0.0356
Toxoplasma gondii hypothetical protein 0.0051 0.0087 0.029
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0001 0.0002
Echinococcus multilocularis muscleblind protein 1 0.1293 0.5723 0.5723
Loa Loa (eye worm) hypothetical protein 0.0094 0.0285 0.045
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0058 0.012 0.0505
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0326 0.0514
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.0609 0.5722
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0042 0.0047 0.0372
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0198 0.0754 0.1318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi Nuclear hormone receptor-like 1 0.009 0.0266 0.0465
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0142 0.05 0.1101
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.009 0.0266 0.0374
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0046 0.0046
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.009 0.0266 0.042
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.012 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.02 0.0515
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0246 0.0974 0.2482
Echinococcus granulosus chromobox protein 1 0.0072 0.0183 0.0183
Echinococcus granulosus serine protein kinase ATM 0.0138 0.0483 0.0483
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0866 0.3786 1
Giardia lamblia Encystation-specific protease 0.0048 0.0073 0.0375
Onchocerca volvulus Fatty acid synthase homolog 0.0195 0.0742 0.3703
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0061 0.0132 0.0103
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0042 0.0047 0.0405
Schistosoma mansoni nuclear hormone receptor 0.009 0.0266 0.0374
Schistosoma mansoni hypothetical protein 0.0061 0.0132 0.0185
Echinococcus granulosus microtubule associated protein 2 0.1 0.4396 0.4396
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0754 0.1982
Brugia malayi hypothetical protein 0.0174 0.0648 0.1132
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0096 0.0293 0.0293
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0246 0.0974 1
Onchocerca volvulus 0.0058 0.012 0.0598
Brugia malayi Probable ClpP-like protease 0.0042 0.0047 0.0082
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0096 0.0293 0.0293
Schistosoma mansoni chromobox protein 0.0072 0.0183 0.0257
Brugia malayi nuclear receptor RXR 0.0043 0.005 0.0088
Mycobacterium ulcerans hypothetical protein 0.0166 0.0609 0.6225
Trypanosoma cruzi GUP1, putative 0.0061 0.0132 0.0231
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.009 0.0266 0.0266
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0866 0.3786 1
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0058 0.012 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.012 0.0304
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0138 0.0483 0.0844

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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