Detailed information for compound 1144685

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 460.46 | Formula: C23H29N2O6P
  • H donors: 1 H acceptors: 2 LogP: 3.32 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)OP(=O)(C1CCCN1C(=O)C1CCCN1)Oc1ccc(cc1)OC
  • InChi: 1S/C23H29N2O6P/c1-28-17-7-11-19(12-8-17)30-32(27,31-20-13-9-18(29-2)10-14-20)22-6-4-16-25(22)23(26)21-5-3-15-24-21/h7-14,21-22,24H,3-6,15-16H2,1-2H3
  • InChiKey: SHIONCUNFVZZAI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.1574 0.1554
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.1611 0.1591
Onchocerca volvulus 0.0048 0.0977 0.1178
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0157 0.051
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0977 0.0955
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.2126 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0335 0.0311
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.1437 0.5164
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.2783 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0157 0.0669
Schistosoma mansoni DNA polymerase eta 0.0092 0.209 0.209
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0977 0.1388
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0286 0.1027
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0029 0.0503 0.2433
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0335 0.0452
Loa Loa (eye worm) hypothetical protein 0.0034 0.0614 0.0892
Schistosoma mansoni hypothetical protein 0.0034 0.0614 0.0614
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0906 0.0884
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Loa Loa (eye worm) hypothetical protein 0.0025 0.0403 0.0586
Trypanosoma cruzi metacaspase, putative 0.0029 0.0502 0.1802
Trypanosoma brucei metacaspase MCA3 0.0029 0.0502 0.1756
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0392 0.0897
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0977 0.0977
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.048 0.0697
Trichomonas vaginalis rotamase, putative 0.0033 0.0597 0.0868
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.2126 0.2107
Brugia malayi Ets-domain containing protein 0.0071 0.1574 0.2259
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0614 0.086
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0977 0.0955
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0067 0.1452 0.1431
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0977 0.0955
Onchocerca volvulus 0.0028 0.048 0.0267
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.023 0.0499
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0838 0.1234
Echinococcus multilocularis thyroid hormone receptor alpha 0.0048 0.0977 0.0955
Schistosoma mansoni rotamase 0.0033 0.0597 0.0597
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0029 0.0503 0.2433
Loa Loa (eye worm) hypothetical protein 0.0029 0.0502 0.0728
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.275 0.3993
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0029 0.0503 0.0466
Plasmodium falciparum DNA repair protein REV1, putative 0.0021 0.0286 0.0636
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.1782 0.6384
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0403 0.0553
Entamoeba histolytica exonuclease, putative 0.001 0.0026 0.0123
Mycobacterium ulcerans glutaminase 0.0269 0.6604 1
Giardia lamblia Flap structure-specific endonuclease 0.0051 0.1065 0.4948
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0355 0.0482
Echinococcus granulosus heat shock protein 90 0.0045 0.0908 0.0886
Leishmania major hypothetical protein, conserved 0.0022 0.0318 0.1433
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0355 0.1668
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0977 0.1418
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0286 0.0977
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0523 0.0346
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0052 0.0188
Brugia malayi hypothetical protein 0.0023 0.0335 0.0452
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0029 0.0503 0.2433
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.2783 1
Brugia malayi TAR-binding protein 0.0063 0.1373 0.1965
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0051 0.1065 0.4973
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0029 0.0503 0.2433
Brugia malayi hypothetical protein 0.0025 0.0403 0.0553
Trypanosoma brucei polo-like protein kinase 0.0093 0.2126 0.7624
Loa Loa (eye worm) hypothetical protein 0.0121 0.2828 0.4107
Trypanosoma brucei cytochrome P450, putative 0.0066 0.1437 0.5137
Echinococcus granulosus DNA repair protein complementing XP G cells 0.001 0.0026 0.0002
Onchocerca volvulus Huntingtin homolog 0.0121 0.2828 0.4574
Brugia malayi Cytochrome P450 family protein 0.0066 0.1437 0.2059
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0523 0.05
Plasmodium vivax endoplasmin, putative 0.0045 0.0908 0.2161
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.1457 0.2116
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0977 0.1388
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.0335 0.0452
Giardia lamblia Grp94/Hsp90 0.0042 0.0838 0.3865
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.052 0.1265
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0024 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0977 0.0955
Schistosoma mansoni heat shock protein 0.0045 0.0908 0.0908
Schistosoma mansoni kinase 0.0047 0.0963 0.0963
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0977 0.1388
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.1009 0.1435
Mycobacterium ulcerans hypothetical protein 0.0023 0.0355 0.0234
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0906 0.0884
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0035
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0908 0.3263
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0286 0.0977
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.023 0.0206
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.017 0.408 0.4066
Leishmania major DNA polymerase kappa, putative 0.0021 0.0286 0.1282
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0977 0.1418
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.023 0.03
Schistosoma mansoni hypothetical protein 0.001 0.0024 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0977 0.0977
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0157 0.0133
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0029 0.0503 0.2433
Toxoplasma gondii XPG N-terminal domain-containing protein 0.001 0.0026 0.0064
Trypanosoma brucei chrX additional, unordered contigs 0.0021 0.0286 0.0977
Trypanosoma cruzi DNA polymerase eta, putative 0.0092 0.209 0.7508
Onchocerca volvulus Huntingtin homolog 0.0121 0.2828 0.4574
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0029 0.0502 0.0502
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.209 0.301
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0428 0.0984
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0066 0.1437 0.1926
Brugia malayi Pax transcription factor protein 2 0.0237 0.5786 0.8397
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.1437 0.2087
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.2783 0.4029
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0355 0.0234
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.1437 0.2087
Toxoplasma gondii XPG N-terminal domain-containing protein 0.001 0.0026 0.0064
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.0335 0.0311
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0392 0.1409
Trichomonas vaginalis flap endonuclease-1, putative 0.0051 0.1065 0.1579
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0924 0.3318
Onchocerca volvulus 0.0133 0.3153 0.5169
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.0908 0.4201
Loa Loa (eye worm) hypothetical protein 0.0025 0.0403 0.0586
Brugia malayi CXXC zinc finger family protein 0.0028 0.048 0.0665
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0503 0.1807
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0368 0.1272
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0083 0.1868 0.8789
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0977 0.1388
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0578 0.2717
Trypanosoma brucei metacaspase 0.0029 0.0502 0.1756
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0335 0.0311
Trichomonas vaginalis DNA polymerase eta, putative 0.0119 0.2783 0.4191
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0335 0.0311
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0523 0.05
Schistosoma mansoni hypothetical protein 0.0073 0.1611 0.1611
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0502 0.0723
Schistosoma mansoni zinc finger protein 0.0023 0.0335 0.0335
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.0742 0.072
Schistosoma mansoni hypothetical protein 0.0029 0.0503 0.0503
Plasmodium vivax metacaspase 1, putative 0.0029 0.0502 0.1165
Trypanosoma cruzi heat shock protein, putative 0.003 0.0523 0.188
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0977 0.0955
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0945 0.4447
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.1123 0.2734
Trypanosoma cruzi DNA repair protein RAD2, putative 0.001 0.0026 0.0094
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0205 0.0669
Brugia malayi RNA binding protein 0.0063 0.1373 0.1965
Schistosoma mansoni tsg101-related 0.0057 0.1211 0.1211
Brugia malayi nuclear hormone receptor 0.0048 0.0977 0.1388
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.023 0.097
Brugia malayi XPG I-region family protein 0.001 0.0026 0.0003
Loa Loa (eye worm) hypothetical protein 0.028 0.6886 1
Toxoplasma gondii XPG N-terminal domain-containing protein 0.001 0.0026 0.0064
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0908 0.3263
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.1373 0.1993
Trypanosoma brucei DNA polymerase eta, putative 0.0092 0.209 0.7494
Brugia malayi Endoplasmin precursor 0.0045 0.0908 0.1288
Plasmodium vivax DNA repair protein REV1, putative 0.0021 0.0286 0.0636
Schistosoma mansoni tar DNA-binding protein 0.0063 0.1373 0.1373
Echinococcus granulosus expressed protein 0.0033 0.0597 0.0575
Schistosoma mansoni exonuclease 0.001 0.0026 0.0026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.018 0.0526
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0051 0.1065 0.2592
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Loa Loa (eye worm) RNA binding protein 0.0063 0.1373 0.1993
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0205 0.0437
Loa Loa (eye worm) glutaminase 0.0269 0.6604 0.9591
Echinococcus granulosus cpg binding protein 0.003 0.0521 0.0498
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Mycobacterium ulcerans heat shock protein 90 0.0042 0.0838 0.0989
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0067 0.1452 0.1431
Schistosoma mansoni survival motor neuron protein 0.0047 0.0968 0.0968
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.0335 0.0311
Leishmania major hypothetical protein, conserved 0.001 0.0026 0.0051
Echinococcus granulosus caspase 8 0.0029 0.0502 0.0479
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0029 0.0503 0.2433
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Entamoeba histolytica hypothetical protein 0.0011 0.0052 0.0246
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0392 0.0955
Schistosoma mansoni tsg101-related 0.0057 0.1211 0.1211
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0157 0.0133
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Entamoeba histolytica deoxycytidyl transferase, putative 0.0067 0.1452 0.6831
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0502 0.0723
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0156 0.0132
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0156 0.0227
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0241 0.0867
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0428 0.0611
Trypanosoma brucei Metacaspase-4 0.0029 0.0502 0.1756
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Entamoeba histolytica hypothetical protein 0.0073 0.1611 0.7581
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0906 0.0906
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0051 0.1065 0.3826
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0977 0.1388
Schistosoma mansoni hypothetical protein 0.0138 0.3271 0.3271
Onchocerca volvulus Bile acid receptor homolog 0.0048 0.0977 0.1178
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0906 0.0906
Schistosoma mansoni glutaminase 0.0269 0.6604 0.6604
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0355 0.1668
Plasmodium falciparum flap endonuclease 1 0.0051 0.1065 0.2545
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Loa Loa (eye worm) hypothetical protein 0.0029 0.0502 0.0728
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.1868 0.28
Schistosoma mansoni tar DNA-binding protein 0.0063 0.1373 0.1373
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0977 0.0977
Loa Loa (eye worm) endoplasmin 0.0045 0.0908 0.1319
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0029 0.0503 0.2433
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0029 0.0503 0.0466
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0029 0.0503 0.2433
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0046 0.0924 0.2248
Echinococcus multilocularis cpg binding protein 0.003 0.0521 0.0498
Loa Loa (eye worm) hypothetical protein 0.0092 0.209 0.3035
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0156 0.0192
Schistosoma mansoni hypothetical protein 0.0016 0.0156 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0052 0.004
Echinococcus granulosus endoplasmin 0.0042 0.0838 0.0816
Echinococcus multilocularis caspase 2 0.0029 0.0502 0.0479
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0029 0.0503 0.0466
Brugia malayi tailless protein 0.0023 0.0335 0.0452
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Echinococcus granulosus tar DNA binding protein 0.0063 0.1373 0.1352
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.1009 0.1435
Treponema pallidum heat shock protein 90 0.0042 0.0838 1
Trypanosoma brucei DNA damage repair protein, putative 0.0021 0.0286 0.0977
Brugia malayi nuclear hormone receptor 0.0023 0.0335 0.0452
Entamoeba histolytica hypothetical protein 0.0011 0.0052 0.0246
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Echinococcus multilocularis endoplasmin 0.0042 0.0838 0.0816
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0318 0.1093
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0335 0.0311
Brugia malayi glutaminase DH11.1 0.0269 0.6604 0.9589
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0156 0.0132
Leishmania major hypothetical protein, conserved 0.0025 0.0392 0.1785
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0597 0.0868
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0597 0.0835
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0502 0.0723
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0042 0.0838 0.3897
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0368 0.1729
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0029 0.0503 0.0466
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0977 0.1178
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0029 0.0503 0.2433
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0021 0.0286 0.0696
Loa Loa (eye worm) hypothetical protein 0.0016 0.0156 0.0227
Leishmania major DNA polymerase eta, putative 0.0092 0.209 0.9829
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0977 0.1418
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0503 0.048
Schistosoma mansoni tar DNA-binding protein 0.0063 0.1373 0.1373
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0578 0.2075
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0977 0.0955
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0042 0.0838 1
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.2783 0.4029
Loa Loa (eye worm) hypothetical protein 0.0049 0.1009 0.1465
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.1617 0.5787
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0157 0.0193
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0157 0.0563
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0578 0.1406
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0977 0.1418
Loa Loa (eye worm) hypothetical protein 0.0233 0.5676 0.8243
Brugia malayi photoreceptor-specific nuclear receptor 0.028 0.6886 1
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.2783 1
Schistosoma mansoni hypothetical protein 0.0016 0.0156 0.0156
Mycobacterium leprae Conserved hypothetical protein 0.0029 0.0503 0.3067
Brugia malayi bZIP transcription factor family protein 0.017 0.408 0.5911
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.1868 0.6712
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0502 0.1802
Schistosoma mansoni hypothetical protein 0.0051 0.1056 0.1056
Echinococcus granulosus heat shock protein 90 0.0039 0.0742 0.072
Brugia malayi MH2 domain containing protein 0.0118 0.275 0.3972
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0403 0.038
Loa Loa (eye worm) hypothetical protein 0.0018 0.023 0.0334
Plasmodium falciparum metacaspase-like protein 0.0029 0.0502 0.1165
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0157 0.0381
Giardia lamblia DINP protein human, muc B family 0.008 0.1782 0.8364
Brugia malayi nuclear receptor NHR-88 0.0048 0.0977 0.1388
Schistosoma mansoni ets 0.001 0.0024 0.0024
Entamoeba histolytica DNA-repair protein, putative 0.001 0.0026 0.0123
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0502 0.0723
Leishmania major DNA polymerase eta, putative 0.0046 0.0924 0.4304
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.0335 0.0452
Entamoeba histolytica hypothetical protein 0.0073 0.1611 0.7581
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0392 0.0897
Leishmania major metacaspase, putative 0.0029 0.0502 0.2304
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.008 0.1782 0.8373
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0977 0.0977
Loa Loa (eye worm) XPG I-region family protein 0.001 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0318 0.1142
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0977 0.1388
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Plasmodium vivax heat shock protein, putative 0.0171 0.4108 1
Plasmodium falciparum endoplasmin, putative 0.0033 0.0594 0.139
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0908 0.4272
Toxoplasma gondii Hsp90 domain-containing protein 0.0171 0.4108 1
Schistosoma mansoni hypothetical protein 0.0011 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Trypanosoma cruzi Heat shock protein 83, putative 0.0045 0.0908 0.3263
Trypanosoma cruzi DNA damage repair protein, putative 0.0021 0.0286 0.1027
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0355 0.0234
Schistosoma mansoni hypothetical protein 0.0047 0.0968 0.0968
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.2126 0.7638
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0029 0.0503 0.0466
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0355 0.1557
Echinococcus granulosus caspase 0.0109 0.253 0.2512
Loa Loa (eye worm) hypothetical protein 0.0017 0.0205 0.0297
Brugia malayi polk-prov protein 0.0073 0.1617 0.2322
Schistosoma mansoni DNA polymerase IV / kappa 0.0021 0.0286 0.0286
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.1258 0.4488
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0335 0.0311
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0403 0.038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0355 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Echinococcus granulosus dna polymerase kappa 0.0119 0.2783 0.2766
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0029 0.0503 0.2433
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0977 0.0955
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0109 0.253 0.2512
Leishmania major heat shock protein, putative 0.003 0.0523 0.2406
Brugia malayi hypothetical protein 0.0023 0.0335 0.0452
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0977 0.0977
Leishmania major cytochrome p450-like protein 0.0029 0.0503 0.231
Trypanosoma brucei Heat shock protein 83, putative 0.0045 0.0908 0.3226
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0119 0.2783 0.4191
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.1868 0.28
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0029 0.0503 0.0466
Trypanosoma brucei DNA damage repair protein, putative 0.0021 0.0286 0.0977
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0368 0.1669
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.0335 0.0311
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.2126 0.2107
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0977 0.1388
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0038
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0156 0.0192
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0657 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0977 0.1388
Trypanosoma brucei DNA repair protein RAD2, putative 0.001 0.0026 0.0039
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0029 0.0503 0.2433
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0977 0.0977
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.1868 0.6694
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0355 0.1608
Trichomonas vaginalis rotamase, putative 0.0032 0.0578 0.0838
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.2783 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0977 0.1388
Brugia malayi hypothetical protein 0.0073 0.1611 0.2313
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0024 0.0035
Schistosoma mansoni DNA helicase recq5 0.0018 0.023 0.023
Schistosoma mansoni eyes absent homolog 0.0087 0.1967 0.1967
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0067 0.1452 0.2109
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0048 0.0977 0.0955
Loa Loa (eye worm) RecQ helicase 0.0045 0.0896 0.1302
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0044 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.1611 0.1591
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Echinococcus granulosus heat shock protein 0.0045 0.0908 0.0886
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0335 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0029 0.0503 0.2433
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0029 0.0503 0.0466
Trypanosoma brucei metacaspase 5, putative 0.0029 0.0502 0.1756
Mycobacterium ulcerans hypothetical protein 0.0021 0.0286 0.0127
Loa Loa (eye worm) hypothetical protein 0.0023 0.0355 0.0515
Loa Loa (eye worm) hypothetical protein 0.0025 0.0392 0.0569
Brugia malayi nuclear receptor RXR 0.0023 0.0335 0.0452
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0157 0.0133
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0977 0.0977
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.1574 0.1554
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0029 0.0503 0.0466
Schistosoma mansoni hypothetical protein 0.0016 0.0156 0.0156
Loa Loa (eye worm) glutaminase 2 0.0269 0.6604 0.9591
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0073 0.1617 0.2349
Echinococcus multilocularis caspase 0.0109 0.253 0.2512
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.023 0.03
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0977 0.0955
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.018 0.0526
Trichomonas vaginalis glutaminase, putative 0.0269 0.6604 1
Brugia malayi Cytochrome P450 family protein 0.0067 0.1457 0.2089
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0578 0.2031
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0083 0.1868 0.878
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0026 0.0094
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0083 0.1868 0.1849
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0029 0.0503 0.2433
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0977 0.0977
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.1868 0.6712
Echinococcus multilocularis dnaJ subfamily B 0.0403 1 1
Echinococcus granulosus flap endonuclease 1 0.0051 0.1065 0.1043
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.2126 0.3063
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0015 0.0037
Echinococcus multilocularis 0.0029 0.0503 0.048
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0083 0.1868 0.1849
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.0335 0.0335
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0029 0.0503 0.0466
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.1258 0.4488
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Echinococcus granulosus ubiquitin specific protease 41 0.0083 0.1868 0.1849
Trypanosoma brucei unspecified product 0.0046 0.0927 0.3294
Loa Loa (eye worm) hypothetical protein 0.0025 0.0403 0.0586
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0403 0.0586
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.023 0.0334
Loa Loa (eye worm) fli-1 protein 0.0217 0.5265 0.7646
Schistosoma mansoni DNA helicase recq1 0.0018 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0205 0.0297
Echinococcus multilocularis caspase 3 0.008 0.179 0.177
Schistosoma mansoni endoplasmin 0.0045 0.0908 0.0908
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0392 0.1409
Mycobacterium leprae putative cytochrome p450 0.0029 0.0503 0.3067
Brugia malayi Cell death protein 3 precursor 0.0029 0.0502 0.0696
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0157 0.0133
Trypanosoma brucei unspecified product 0.0106 0.2453 0.8807
Mycobacterium tuberculosis Conserved hypothetical protein 0.0067 0.1452 0.8047
Onchocerca volvulus 0.0023 0.0355 0.0037
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.0335 0.0486
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Schistosoma mansoni ets-related 0.001 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0136 0.3212 0.4665
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.023 0.0559
Schistosoma mansoni elf1 0.001 0.0024 0.0024
Onchocerca volvulus 0.0237 0.5786 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0156 0.0132
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0908 0.1341
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0029 0.0503 0.1761
Loa Loa (eye worm) hypothetical protein 0.0017 0.0205 0.0297
Schistosoma mansoni cytochrome P450 0.0029 0.0503 0.0503
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0742 0.2668
Brugia malayi hypothetical protein 0.0025 0.0403 0.0553
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0083 0.1868 0.1868
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0029 0.0503 0.0466
Loa Loa (eye worm) hypothetical protein 0.0121 0.2828 0.4107
Echinococcus granulosus GPCR family 2 0.0016 0.0156 0.0132
Schistosoma mansoni nuclear receptor 0.0023 0.0335 0.0335
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0968 0.1375
Loa Loa (eye worm) hypothetical protein 0.0025 0.0403 0.0586
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0157 0.0133
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0083 0.1868 0.2688
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0503 0.1807
Schistosoma mansoni hypothetical protein 0.0403 1 1
Echinococcus multilocularis dna polymerase kappa 0.0119 0.2783 0.2766
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0205 0.5
Schistosoma mansoni cpg binding protein 0.0028 0.048 0.048
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0286 0.1027
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0403 0.0403
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0029 0.0503 0.0466
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.1373 0.1965
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0254 0.6222 0.9036
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Toxoplasma gondii heat shock protein HSP90 0.0045 0.0908 0.2211
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0977 0.1178
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0758 0.1794
Brugia malayi hypothetical protein 0.0087 0.1967 0.2831
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0029 0.0503 0.0466
Loa Loa (eye worm) hypothetical protein 0.0017 0.0205 0.0297
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0029 0.0503 0.0466
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0029 0.0503 0.2433
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0523 0.1835
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0157 0.0133
Schistosoma mansoni caspase-7 (C14 family) 0.0029 0.0502 0.0502
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0029 0.0503 0.2433
Brugia malayi steroid hormone receptor 0.0048 0.0977 0.1388
Loa Loa (eye worm) TAR-binding protein 0.0063 0.1373 0.1993
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0932 0.1377
Loa Loa (eye worm) hypothetical protein 0.0083 0.1868 0.2713
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0355 0.1608
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.001 0.0026 0.0002
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Loa Loa (eye worm) cytochrome P450 0.0029 0.0503 0.073
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.023 0.0206
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0157 0.0386
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0042 0.0838 0.4414
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.275 0.3993
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.1868 0.28
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0368 0.1321
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.0335 0.0452
Schistosoma mansoni hypothetical protein 0.0016 0.0156 0.0156
Echinococcus granulosus exonuclease 1 0.001 0.0026 0.0002
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0742 0.1089
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.1574 0.2286
Schistosoma mansoni coup transcription factor 0.0048 0.0977 0.0977
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0977 0.1418
Loa Loa (eye worm) CYP4Cod1 0.0066 0.1437 0.2087
Plasmodium falciparum heat shock protein 90 0.0045 0.0908 0.2161
Brugia malayi nuclear receptor RXR 0.0025 0.0403 0.0553
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0908 0.3263
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0038
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0594 0.0863
Brugia malayi hypothetical protein 0.0121 0.2828 0.4086
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0156 0.0132
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0977 0.0977
Onchocerca volvulus Cell death protein 3 homolog 0.0029 0.0502 0.0306
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0157 0.032
Loa Loa (eye worm) hypothetical protein 0.0165 0.3962 0.5753
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.1437 0.5164
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.008 0.1782 1
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.0335 0.0335
Plasmodium vivax flap endonuclease 1, putative 0.0051 0.1065 0.2545
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0048 0.0977 0.0955
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0896 0.1271
Schistosoma mansoni heat shock protein 0.003 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.0087 0.1967 0.2857
Schistosoma mansoni tar DNA-binding protein 0.0063 0.1373 0.1373
Schistosoma mansoni flap endonuclease-1 0.0046 0.094 0.094
Schistosoma mansoni cpg binding protein 0.003 0.0521 0.0521
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0977 0.0977
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0157 0.051
Echinococcus multilocularis tar DNA binding protein 0.0063 0.1373 0.1352
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0838 0.1234
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0205 0.0437
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.0335 0.0311
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0502 0.1165
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.018 0.0526
Loa Loa (eye worm) hypothetical protein 0.0037 0.0696 0.101
Leishmania major cytochrome p450-like protein 0.0066 0.1437 0.6737
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0034 0.0616 0.15
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0029 0.0503 0.0466
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.001 0.0026 0.0026
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.5676 0.5665
Brugia malayi Fli-1 protein 0.0217 0.5265 0.7637
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0355 0.0234
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.0335 0.0311
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0188
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.2126 0.2126
Schistosoma mansoni terminal deoxycytidyl transferase 0.0067 0.1452 0.1452
Brugia malayi Steroid receptor seven-up type 2 0.0048 0.0977 0.1388
Loa Loa (eye worm) pax transcription factor protein 2 0.0237 0.5786 0.8402
Trypanosoma cruzi metacaspase, putative 0.0029 0.0502 0.1802
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0029 0.0503 0.0466
Brugia malayi Ets-domain containing protein 0.0071 0.1574 0.2259
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0029 0.0503 0.2433
Loa Loa (eye worm) hypothetical protein 0.0017 0.0205 0.0297
Trypanosoma cruzi DNA damage repair protein, putative 0.0021 0.0286 0.1027
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0029 0.0503 0.2433
Toxoplasma gondii XPG N-terminal domain-containing protein 0.001 0.0026 0.0064
Loa Loa (eye worm) hypothetical protein 0.0061 0.1311 0.1904
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0906 0.1316
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.1286 0.1286
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.0335 0.0311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0977 0.1418
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0908 0.3226
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0355 0.1557
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0742 0.3412
Plasmodium falciparum heat shock protein 90, putative 0.0171 0.4108 1
Brugia malayi follicle stimulating hormone receptor 0.0254 0.6222 0.9032
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0029 0.0503 0.0466
Entamoeba histolytica hypothetical protein 0.0073 0.1611 0.7581
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0042 0.0838 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Schistosoma mansoni tsg101-related 0.0047 0.0945 0.0945
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0069 0.1502 0.1481
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0083 0.1868 0.1849
Brugia malayi ImpB/MucB/SamB family protein 0.0067 0.1452 0.2081
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0502 0.1221
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0024 0.0035
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0029 0.0503 0.1807
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0977 0.1388
Loa Loa (eye worm) hypothetical protein 0.0069 0.1502 0.2181
Brugia malayi hypothetical protein 0.0233 0.5676 0.8236
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0908 0.4272
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Brugia malayi cytochrome P450 0.0029 0.0503 0.0698
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.2126 0.7638
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0977 0.1388
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0977 0.1388
Echinococcus multilocularis exonuclease 1 0.001 0.0026 0.0002
Echinococcus multilocularis ubiquitin specific protease 41 0.0083 0.1868 0.1849
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0069 0.1502 0.1481
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.1258 0.4488
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Trypanosoma cruzi DNA repair protein RAD2, putative 0.001 0.0026 0.0094
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.1009 0.1465
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0355 0.0482
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0502 0.1221
Echinococcus multilocularis expressed protein 0.0033 0.0597 0.0575
Loa Loa (eye worm) heat shock protein 75 0.003 0.0523 0.076
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Trypanosoma cruzi metacaspase, putative 0.0029 0.0502 0.1802
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.0335 0.0486
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Brugia malayi nuclear receptor NHR-67 0.0023 0.0335 0.0452
Echinococcus multilocularis caspase 8 0.0029 0.0502 0.0479
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0051 0.1065 0.3792
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0157 0.032
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0029 0.0503 0.0466
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0157 0.0157
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0594 0.0863
Brugia malayi hypothetical protein 0.0133 0.3153 0.4559
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0029 0.0503 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0052 0.004
Loa Loa (eye worm) flap endonuclease-1 0.0051 0.1065 0.1547
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0368 0.0519
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.017 0.408 0.4066
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0403 0.0553
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0977 0.1418
Echinococcus granulosus dna polymerase eta 0.0092 0.209 0.2071
Brugia malayi Cytochrome P450 family protein 0.0066 0.1437 0.2059
Echinococcus granulosus flap endonuclease GEN 1 0.001 0.0026 0.0002
Schistosoma mansoni gabp alpha 0.0071 0.1574 0.1574
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.001 0.0026 0.0026
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.1611 0.1611
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0157 0.0563
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0392 0.0897
Brugia malayi hypothetical protein 0.0069 0.1502 0.2154
Echinococcus multilocularis flap endonuclease GEN 1 0.001 0.0026 0.0002
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0529 0.1231
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.2126 1
Schistosoma mansoni caspase-7 (C14 family) 0.0109 0.253 0.253
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0355 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0502 0.0723
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0896 0.1323
Plasmodium vivax heat shock protein 90, putative 0.003 0.0523 0.1218
Trypanosoma brucei metacaspase MCA2 0.0029 0.0502 0.1756
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.5676 0.5665
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0392 0.1361
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0024 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0977 0.1388
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0906 0.0884
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0015 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0052 0.0188
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.023 0.0559
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0355 0.0482
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0335 0.0452
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0742 0.2668
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Trichomonas vaginalis hypothetical protein 0.0033 0.0609 0.0886
Brugia malayi isocitrate dehydrogenase 0.0016 0.0157 0.0193
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Trypanosoma cruzi metacaspase, putative 0.0029 0.0502 0.1802
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.0335 0.0335
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0355 0.1608
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.0335 0.0486
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.0908 0.3263
Echinococcus granulosus jun protein 0.017 0.408 0.4066
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0977 0.0955
Trypanosoma brucei heat shock protein, putative 0.0045 0.0908 0.3226
Loa Loa (eye worm) hypothetical protein 0.0023 0.0355 0.0515
Plasmodium falciparum metacaspase 1 0.0029 0.0502 0.1165
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0977 0.0955
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0029 0.0503 0.0466
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0109 0.253 0.2512
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0977 0.0955
Leishmania major DNA damage repair protein, putative 0.0021 0.0286 0.1282
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.2783 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0403 0.0586
Entamoeba histolytica hypothetical protein 0.0011 0.0052 0.0246
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0502 0.1802
Schistosoma mansoni hypothetical protein 0.001 0.0024 0.0024
Schistosoma mansoni cpg binding protein 0.003 0.0521 0.0521
Schistosoma mansoni heat shock protein 0.0045 0.0908 0.0908
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0977 0.0977
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0977 0.0955
Loa Loa (eye worm) hypothetical protein 0.0023 0.0355 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0932 0.1377
Echinococcus multilocularis heat shock protein 0.0045 0.0908 0.0886
Brugia malayi heat shock protein 90 0.0045 0.0908 0.1288
Echinococcus multilocularis heat shock protein 90 0.0045 0.0908 0.0886
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0578 0.2075
Brugia malayi ecdysone receptor 0.0023 0.0335 0.0452
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0896 0.1323
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0977 0.1418
Brugia malayi conserved hypotetical protein 0.0023 0.0335 0.0452
Schistosoma mansoni ets-related 0.0217 0.5265 0.5265
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0977 0.0955
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0044 0.002
Loa Loa (eye worm) hypothetical protein 0.0087 0.1967 0.2857
Giardia lamblia DNA damage repair protein 0.0021 0.0286 0.1237
Brugia malayi Cytochrome P450 family protein 0.0029 0.0503 0.0698
Schistosoma mansoni caspase-3 (C14 family) 0.0109 0.253 0.253
Toxoplasma gondii heat shock protein 90, putative 0.0045 0.0908 0.2211
Loa Loa (eye worm) heat shock protein 90 0.0045 0.0908 0.1319
Schistosoma mansoni nuclear receptor 0.0023 0.0335 0.0335
Echinococcus multilocularis heat shock protein 90 0.0039 0.0742 0.072
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0029 0.0503 0.231
Echinococcus multilocularis GPCR, family 2 0.0016 0.0156 0.0132
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0523 0.2461
Echinococcus granulosus caspase 3 0.008 0.179 0.177
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0067 0.1452 0.1452
Toxoplasma gondii cytochrome p450 superfamily protein 0.0029 0.0503 0.1224
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0977 0.0977
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0029 0.0502 0.0696
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0906 0.0906
Brugia malayi nuclear receptor NHR-88 0.0023 0.0335 0.0452
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0029 0.0503 0.2433
Brugia malayi hypothetical protein 0.0016 0.0169 0.021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0906 0.1286
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0977 0.0955
Echinococcus multilocularis dna polymerase eta 0.0092 0.209 0.2071
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.023 0.0206
Brugia malayi Hsp90 protein 0.003 0.0523 0.0727
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0355 0.0234
Entamoeba histolytica exonuclease, putative 0.001 0.0026 0.0123
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.2126 0.3286
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.0335 0.0452
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0896 0.0874
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0335 0.0311
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0906 0.0884
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Leishmania major DNA polymerase kappa, putative 0.008 0.1782 0.8373
Echinococcus granulosus bloom syndrome protein 0.0045 0.0896 0.0874
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0502 0.1221
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0083 0.1868 0.8774
Schistosoma mansoni jun-related protein 0.0138 0.3271 0.3271
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.1617 0.5787
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0157 0.0381
Schistosoma mansoni endoplasmin 0.0045 0.0908 0.0908
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0355 0.0234
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0029 0.0503 0.2433
Leishmania major cytochrome p450-like protein 0.0029 0.0503 0.231
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0026 0.0094
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.2126 0.3087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0335 0.0486
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0015 0.0055
Trypanosoma brucei exonuclease, putative 0.001 0.0026 0.0039
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0908 0.3226
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0011 0.0052 0.0134
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0083 0.1868 0.1868
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.2126 0.3192
Brugia malayi Flap endonuclease-1 0.0051 0.1065 0.1517
Trypanosoma brucei DNA polymerase IV, putative 0.0106 0.2453 0.8807
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0083 0.1868 0.1849
Echinococcus multilocularis jun protein 0.017 0.408 0.4066
Loa Loa (eye worm) DR-78 0.0023 0.0335 0.0486
Echinococcus granulosus caspase 2 0.0029 0.0502 0.0479
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0029 0.0503 0.2433
Echinococcus multilocularis flap endonuclease 1 0.0051 0.1065 0.1043
Plasmodium vivax heat shock protein 86, putative 0.0045 0.0908 0.2161
Schistosoma mansoni tar DNA-binding protein 0.0063 0.1373 0.1373
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0024 0.0035
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.2783 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0977 0.1388
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0335 0.0335
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0502 0.0723
Entamoeba histolytica Flap nuclease, putative 0.0051 0.1065 0.501
Onchocerca volvulus 0.0047 0.0968 0.1161
Brugia malayi hypothetical protein 0.0025 0.0392 0.0536
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0157 0.0228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.018 0.0526
Trypanosoma brucei unspecified product 0.0046 0.0927 0.3294
Entamoeba histolytica hypothetical protein 0.0011 0.0052 0.0246
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.023 0.0206
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0597 0.0867
Loa Loa (eye worm) hypothetical protein 0.0048 0.0977 0.1418
Giardia lamblia Kinase, PLK 0.0093 0.2126 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0977 0.0955
Brugia malayi ecdysteroid receptor 0.0048 0.0977 0.1388
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0578 0.2664
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0502 0.0723
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0029 0.0503 0.0466
Leishmania major heat shock protein 83-1 0.0045 0.0908 0.4231
Entamoeba histolytica hypothetical protein 0.0073 0.1611 0.7581
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0523 0.1273
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.2783 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0355 0.1668

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.