Detailed information for compound 1161863

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.795 | Formula: C20H15ClF2N2O3
  • H donors: 2 H acceptors: 3 LogP: 4.84 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cccc(c1)NCc1c(F)cc2c(c1F)n(cc(c2=O)C(=O)O)C1CC1
  • InChi: 1S/C20H15ClF2N2O3/c21-10-2-1-3-11(6-10)24-8-14-16(22)7-13-18(17(14)23)25(12-4-5-12)9-15(19(13)26)20(27)28/h1-3,6-7,9,12,24H,4-5,8H2,(H,27,28)
  • InChiKey: HOCTVQWLTFHVKV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Onchocerca volvulus 0.002 0.0133 0.0234
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0266 0.0383
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.008 0.0073
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0376 0.0481
Trichomonas vaginalis aldo/keto reductase, putative 0.0144 0.1521 0.2806
Schistosoma mansoni smad1 5 8 and 0.0042 0.0383 0.049
Loa Loa (eye worm) acetyltransferase 0.0165 0.1755 0.2528
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0266 0.0338
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0047 0.0171
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.0144
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.3241 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0266 0.0392
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Chlamydia trachomatis AMP nucleosidase 0.0026 0.0198 1
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0008 0.0007 0.001
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0266 0.0338
Schistosoma mansoni hypothetical protein 0.0078 0.0784 0.1013
Schistosoma mansoni hypothetical protein 0.0697 0.7672 1
Echinococcus granulosus bloom syndrome protein 0.0012 0.0047 0.0051
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0012 0.0047 0.0067
Schistosoma mansoni hypothetical protein 0.0631 0.6941 0.9047
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0153 0.0271
Leishmania major aldo-keto reductase-like protein 0.0144 0.1521 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Brugia malayi nuclear receptor RXR 0.0017 0.01 0.0147
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0022 0.0009
Brugia malayi hypothetical protein 0.0015 0.008 0.0118
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0153 0.019
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0011 0.0038 0.0116
Trichomonas vaginalis aldo-keto reductase, putative 0.0042 0.0379 0.069
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0266 0.0259
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0026 0.0198 0.1182
Echinococcus granulosus smad 0.0042 0.0383 0.049
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0133 0.0126
Toxoplasma gondii aldo-keto reductase 0.0042 0.0379 0.2389
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0021 0.003
Echinococcus granulosus dnaJ subfamily B 0.0457 0.5001 0.6516
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0105 0.1079 0.1588
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0153 0.0881
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Leishmania major importin beta-1 subunit, putative 0.0048 0.0448 0.2845
Echinococcus granulosus neuropeptide s receptor 0.0473 0.5178 0.6747
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0266 0.0392
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0398 0.2516
Echinococcus multilocularis aldo keto reductase 0.0144 0.1521 0.1514
Onchocerca volvulus 0.0042 0.0379 0.069
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0165 0.1755 0.228
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Schistosoma mansoni coup transcription factor 0.0032 0.0266 0.0338
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0266 0.0338
Schistosoma mansoni methylthioadenosine phosphorylase 0.0026 0.0198 0.0249
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0047 0.0171
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0192 0.1143
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.002 0.0133 0.0192
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0123 0.1287 0.1894
Onchocerca volvulus 0.002 0.0133 0.0234
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.005 0.0056
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0448 0.2845
Echinococcus granulosus transcription factor Dp 1 0.0045 0.0414 0.0531
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0133 0.0196
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0021 0.003
Brugia malayi Pre-SET motif family protein 0.0433 0.4735 0.6968
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.0144
Schistosoma mansoni DNA helicase recq5 0.0012 0.0047 0.0051
Loa Loa (eye worm) oxidoreductase 0.0144 0.1521 0.2191
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0508 0.5567 1
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.002 0.0133 0.0196
Loa Loa (eye worm) hypothetical protein 0.0025 0.0192 0.0277
Echinococcus granulosus importin 5 0.0011 0.0038 0.0041
Mycobacterium leprae probable uridine phosphorylase 0.0026 0.0198 0.0134
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0078 0.0778 0.1006
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0591
Loa Loa (eye worm) DR-78 0.0015 0.008 0.0115
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0094 0.123
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.002 0.0133 0.0126
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Brugia malayi CXXC zinc finger family protein 0.0032 0.0271 0.0399
Schistosoma mansoni purine nucleoside phosphorylase 0.0123 0.1287 0.167
Entamoeba histolytica hypothetical protein 0.0078 0.0784 0.2401
Echinococcus granulosus hypothetical protein 0.0144 0.1521 0.1975
Loa Loa (eye worm) hypothetical protein 0.0032 0.0273 0.0394
Echinococcus multilocularis integrin alpha ps 0.003 0.0245 0.0238
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0012 0.0047 0.0039
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.01 0.0121
Entamoeba histolytica hypothetical protein 0.0078 0.0784 0.2401
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.002 0.0133 0.0164
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0042 0.0379 0.2389
Schistosoma mansoni hypothetical protein 0.0081 0.0811 0.1049
Treponema pallidum pfs protein (pfs) 0.0026 0.0198 0.0059
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0266 0.0338
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0153 0.0146
Mycobacterium tuberculosis Hypothetical protein 0.0026 0.0198 0.0723
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0123 0.0116
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.002 0.0133 0.0192
Echinococcus granulosus peregrin 0.0034 0.0291 0.037
Brugia malayi nuclear hormone receptor 0.0015 0.008 0.0118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.2087 0.2714
Brugia malayi nuclear receptor RXR 0.0015 0.008 0.0118
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0094 0.0485
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.3241 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0015 0.001
Echinococcus multilocularis integrin alpha ps 0.0062 0.0605 0.0598
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0398 0.1101
Schistosoma mansoni integrin alpha-ps 0.0062 0.0605 0.0779
Schistosoma mansoni nuclear hormone receptor 0.0015 0.008 0.0095
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0144 0.1521 0.2806
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0028 0.0027
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0266 0.0338
Schistosoma mansoni survival motor neuron protein 0.0105 0.108 0.14
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Echinococcus multilocularis nAChR subunit 0.002 0.0133 0.0126
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0094 0.0113
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0255 0.2749 0.3961
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0144 0.1521 0.2238
Brugia malayi hypothetical protein 0.0016 0.0094 0.0138
Brugia malayi MH1 domain containing protein 0.0042 0.0383 0.0563
Schistosoma mansoni hypothetical protein 0.0081 0.0811 0.1049
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0316 0.0309
Onchocerca volvulus 0.0144 0.1521 0.2806
Schistosoma mansoni ran 0.0044 0.0398 0.051
Giardia lamblia Aldose reductase 0.0144 0.1521 0.4614
Brugia malayi kap beta 3 protein 0.0011 0.0038 0.0056
Schistosoma mansoni hypothetical protein 0.0457 0.5001 0.6516
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0144 0.1521 0.2806
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0047 0.0171
Loa Loa (eye worm) hypothetical protein 0.0051 0.0483 0.0696
Echinococcus multilocularis survival motor neuron protein 1 0.0513 0.5631 0.5628
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0383 0.049
Brugia malayi conserved hypotetical protein 0.0015 0.008 0.0118
Echinococcus multilocularis aldo keto reductase 0.0144 0.1521 0.1514
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0383 0.0376
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0012 0.0047 0.0039
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.01 0.0144
Echinococcus multilocularis purine nucleoside phosphorylase 0.0123 0.1287 0.1281
Brugia malayi Nuclear hormone receptor E75 0.0015 0.008 0.0118
Mycobacterium ulcerans oxidoreductase 0.0144 0.1521 0.9865
Schistosoma mansoni importin beta-1 0.0059 0.0572 0.0737
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0192 0.29
Brugia malayi MH2 domain containing protein 0.0042 0.0383 0.0563
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0123 0.0116
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.008 0.0118
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0133 0.0126
Trypanosoma brucei unspecified product 0.0015 0.0079 0.0386
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0009 0.0015 0.0022
Onchocerca volvulus 0.0144 0.1521 0.2806
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Echinococcus multilocularis smad 0.0042 0.0383 0.0376
Trypanosoma brucei prostaglandin f synthase 0.0144 0.1521 1
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0008 0.0007 0.0011
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.0007 0.0011
Brugia malayi jmjC domain containing protein 0.001 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0627 0.4039
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0627 0.0808
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.1001 0.0994
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0008 0.0007 0.0011
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0398 0.6847
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0153 0.019
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0094 0.0485
Echinococcus multilocularis purine nucleoside phosphorylase 0.0098 0.1003 0.0996
Schistosoma mansoni hypothetical protein 0.001 0.0022 0.002
Schistosoma mansoni nuclear receptor 0.0015 0.008 0.0095
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0026 0.0198 0.2998
Brugia malayi hypothetical protein 0.0513 0.5631 0.8286
Echinococcus multilocularis aldo keto reductase 0.0144 0.1521 0.1514
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.002 0.0133 0.0196
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0011 0.0032 0.0047
Schistosoma mansoni methylthioadenosine phosphorylase 0.0026 0.0198 0.0249
Schistosoma mansoni importin-beta 2 0.0011 0.0038 0.0041
Echinococcus multilocularis musashi 0.0014 0.0075 0.0068
Brugia malayi hypothetical protein 0.0008 0.0007 0.0011
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0133 0.0126
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.008 0.0073
Echinococcus multilocularis transportin 1 0.0011 0.0038 0.0031
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0094 0.0485
Entamoeba histolytica hypothetical protein 0.0024 0.018 0.0534
Entamoeba histolytica hypothetical protein 0.0011 0.0032 0.0077
Echinococcus granulosus integrin alpha ps 0.0062 0.0605 0.0779
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0631 0.6941 1
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0144 0.1521 0.9863
Brugia malayi nuclear receptor NHR-88 0.0032 0.0266 0.0392
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0133 0.0192
Brugia malayi hypothetical protein 0.0009 0.0015 0.0022
Leishmania major nucleoside phosphorylase-like protein 0.0026 0.0198 0.1182
Echinococcus multilocularis integrin alpha 3 0.003 0.0245 0.0238
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0044 0.0391
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0627 0.3416
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0266 0.0338
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0094 0.0138
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Brugia malayi nuclear hormone receptor 0.0032 0.0266 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0266 0.0392
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0336 0.0429
Loa Loa (eye worm) intermediate filament protein 0.0014 0.0075 0.0108
Echinococcus multilocularis purine nucleoside phosphorylase 0.0123 0.1287 0.1281
Toxoplasma gondii phosphorylase family protein 0.0026 0.0198 0.1182
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0266 0.0259
Leishmania major methylthioadenosine phosphorylase, putative 0.0026 0.0198 0.1182
Brugia malayi jmjC domain containing protein 0.001 0.0021 0.0031
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0123 0.1287 0.2373
Brugia malayi G-protein alpha subunit 0.0008 0.0007 0.0011
Brugia malayi Bloom's syndrome protein homolog 0.0012 0.0047 0.0069
Brugia malayi uridine phosphorylase family protein 0.0026 0.0198 0.0292
Schistosoma mansoni smad 0.0042 0.0383 0.049
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.1539 1
Brugia malayi RNA, U transporter 1 0.0168 0.1786 0.2628
Leishmania major prostaglandin f synthase, putative 0.0144 0.1521 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0012 0.0047 0.0466
Entamoeba histolytica HEAT repeat domain containing protein 0.0011 0.0038 0.0096
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0192 0.1143
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0266 0.0392
Brugia malayi MH2 domain containing protein 0.0042 0.0383 0.0563
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0079 0.0386
Echinococcus multilocularis JmjC domain containing protein 4 0.001 0.0021 0.0014
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0094 0.0135
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0697 0.09
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0008 0.0007 0.001
Schistosoma mansoni integrin alpha-ps 0.0032 0.0273 0.0347
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0008 0.0007 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0266 0.0338
Echinococcus multilocularis dnaJ subfamily B 0.0457 0.5001 0.4998
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0026 0.0198 0.0325
Echinococcus granulosus dna polymerase eta 0.0021 0.0153 0.019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0612 0.0605
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Entamoeba histolytica hypothetical protein 0.0048 0.0448 0.1362
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.002 0.0133 0.0192
Leishmania major DNA polymerase eta, putative 0.0021 0.0153 0.0881
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0012 0.0047 0.0051
Schistosoma mansoni phosphatidylserine receptor 0.001 0.0021 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.2087 0.2714
Brugia malayi jmjC domain containing protein 0.0038 0.0336 0.0494
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.002 0.0133 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0266 0.0392
Echinococcus multilocularis purine nucleoside phosphorylase 0.0098 0.1003 0.0996
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0144 0.1521 0.2238
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Schistosoma mansoni hypothetical protein 0.0697 0.7672 1
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0153 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0266 0.0392
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.0007 0.0011
Echinococcus granulosus uridine phosphorylase 1 0.0026 0.0198 0.0249
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.008 0.0095
Mycobacterium ulcerans hypothetical protein 0.0042 0.0379 0.1631
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.3241 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Onchocerca volvulus 0.002 0.0133 0.0234
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.018 0.1061
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.01 0.0147
Plasmodium falciparum importin beta, putative 0.0059 0.0572 1
Onchocerca volvulus 0.0015 0.008 0.0135
Loa Loa (eye worm) G protein alpha subunit 3 0.0008 0.0007 0.001
Schistosoma mansoni zinc finger protein 0.0015 0.008 0.0095
Entamoeba histolytica hypothetical protein 0.0078 0.0784 0.2401
Echinococcus granulosus snurportin 1 0.0631 0.6941 0.9047
Echinococcus multilocularis GPCR, family 2 0.0081 0.0811 0.0804
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.003
Onchocerca volvulus 0.0009 0.0015 0.0015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0627 0.3687
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0094 0.0113
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0455 0.7345
Brugia malayi hypothetical protein 0.0078 0.0784 0.1153
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Trichomonas vaginalis aldo/keto reductase, putative 0.0144 0.1521 0.2806
Loa Loa (eye worm) hypothetical protein 0.003 0.0245 0.0353
Echinococcus granulosus lamin 0.0014 0.0075 0.0088
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0041 0.0034
Onchocerca volvulus 0.002 0.0133 0.0234
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0078 0.0778 0.1145
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.008 0.0118
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0612 0.0605
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0008 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.1539 1
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0042 0.0379 0.0485
Giardia lamblia Aldose reductase 0.0144 0.1521 0.4614
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.008 0.0095
Brugia malayi Calcitonin receptor-like protein seb-1 0.0255 0.2749 0.4046
Schistosoma mansoni protein phosphatase 2C 0.001 0.0021 0.0018
Plasmodium falciparum purine nucleoside phosphorylase 0.0026 0.0198 0.3216
Mycobacterium leprae Conserved hypothetical protein 0.0102 0.1055 0.6439
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0144 0.1521 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0246 0.0354
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0336 0.0429
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0039 0.0032
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0612 0.0789
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0038 0.0055
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0123 0.1287 0.8256
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0042 0.0379 0.069
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0266 0.0338
Trypanosoma cruzi aldo-keto reductase 0.0144 0.1521 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0026 0.0198 0.0591
Brugia malayi jmjC domain containing protein 0.0098 0.1001 0.1473
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.041 0.1246
Loa Loa (eye worm) hypothetical protein 0.0255 0.2749 0.3961
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0078 0.0778 0.5048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0627 0.3416
Leishmania major GTP-binding protein, putative 0.0044 0.0398 0.2516
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.002 0.0133 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Onchocerca volvulus 0.0144 0.1521 0.2806
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0123 0.1287 0.2373
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0011 0.0038 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Loa Loa (eye worm) oxidoreductase 0.0144 0.1521 0.2191
Trichomonas vaginalis aldo/keto reductase, putative 0.0144 0.1521 0.2806
Onchocerca volvulus 0.0493 0.5401 1
Brugia malayi MH2 domain containing protein 0.0618 0.6796 1
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0047 0.0073
Schistosoma mansoni nAChR subunit 0.0009 0.0015 0.001
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.002 0.0133 0.0192
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Plasmodium vivax hypothetical protein, conserved 0.003 0.0246 0.3802
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0398 0.0391
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0192 0.1143
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0266 0.0338
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0627 0.3416
Loa Loa (eye worm) hypothetical protein 0.0513 0.5631 0.8113
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0042 0.0379 0.0558
Echinococcus granulosus aldehyde reductase 0.0102 0.1055 0.1367
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0784 0.1013
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.008 0.0115
Schistosoma mansoni lamin 0.0014 0.0075 0.0088
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0026 0.0198 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0266 0.0383
Schistosoma mansoni aldo-keto reductase 0.0144 0.1521 0.1975
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0133 0.0196
Echinococcus granulosus geminin 0.0697 0.7672 1
Schistosoma mansoni cpg binding protein 0.0034 0.0291 0.0371
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.2087 0.2082
Echinococcus multilocularis integrin alpha ps 0.0062 0.0605 0.0598
Schistosoma mansoni phd/f-box containing protein 0.001 0.0021 0.0018
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0455 0.0831
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.01 0.0121
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0398 0.2516
Brugia malayi Cation transporter family protein 0.002 0.0133 0.0196
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0383 0.0376
Echinococcus granulosus cpg binding protein 0.0034 0.0291 0.0371
Echinococcus multilocularis voltage gated potassium channel subunit 0.0042 0.0379 0.0372
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Brugia malayi hypothetical protein 0.0009 0.0015 0.0022
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0047 0.0122
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0153 0.0271
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.01 0.0147
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0246 0.1499
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0026 0.0198 0.1182
Echinococcus granulosus survival motor neuron protein 1 0.0513 0.5631 0.7338
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.2087 0.3072
Schistosoma mansoni integrin alpha 0.0062 0.0605 0.0779
Trichomonas vaginalis set domain proteins, putative 0.0493 0.5401 1
Echinococcus granulosus aldo keto reductase 0.0144 0.1521 0.1975
Schistosoma mansoni jumonji domain containing protein 0.001 0.0021 0.0018
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.008 0.0095
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0026 0.0198 0.0286
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0572 0.0565
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0042 0.0379 0.0546
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0133 0.0164
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.008 0.0135
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0042 0.0379 0.2389
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.0144
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0266 0.0259
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0455 0.0831
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0448 0.0817
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0266 0.0338
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0038 0.0116
Onchocerca volvulus 0.0014 0.0075 0.0125
Onchocerca volvulus 0.0032 0.0266 0.048
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0041 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0811 0.0804
Schistosoma mansoni nAChR subunit 0.0009 0.0015 0.001
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0011 0.0032 0.0032
Schistosoma mansoni polycystin 1-related 0.0045 0.0411 0.0526
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0012 0.0047 0.0051
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.0007 0.0011
Echinococcus granulosus intermediate filament protein 0.0014 0.0075 0.0088
Entamoeba histolytica hypothetical protein 0.0078 0.0784 0.2401
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0192 0.311
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0026 0.0198 0.1182
Leishmania major DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0094 0.0087
Brugia malayi MTAP 0.0026 0.0198 0.0292
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0094 0.0087
Echinococcus granulosus transportin 1 0.0011 0.0038 0.0041
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.018 0.1061
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0157 0.0231
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.002 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.003
Leishmania major hypothetical protein, conserved 0.0025 0.0192 0.1143
Echinococcus multilocularis lamin 0.0014 0.0075 0.0068
Echinococcus multilocularis jumonji domain containing 1A 0.001 0.0021 0.0014
Toxoplasma gondii phosphorylase family protein 0.0026 0.0198 0.1182
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0028 0.0021
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.002 0.0133 0.0164
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0079 0.0386
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.002 0.0133 0.0126
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0266 0.0338
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.1539 1
Brugia malayi Cation transporter family protein 0.002 0.0133 0.0196
Echinococcus granulosus nAChR subunit 0.0011 0.0032 0.0032
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0266 0.0259
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Schistosoma mansoni cpg binding protein 0.0034 0.0291 0.0371
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0133 0.0164
Treponema pallidum uridine phosphorylase (udp) 0.0026 0.0198 0.0059
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0078 0.0778 0.5048
Echinococcus multilocularis importin 5 0.0011 0.0038 0.0031
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0153 0.0225
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.2087 0.3007
Entamoeba histolytica alcohol dehydrogenase, putative 0.0042 0.0379 0.115
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0266 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Echinococcus granulosus aldo keto reductase 0.0144 0.1521 0.1975
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Entamoeba histolytica aldose reductase, putative 0.0144 0.1521 0.468
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0094 0.0485
Echinococcus multilocularis phd:f box containing protein 0.001 0.0021 0.0014
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0133 0.0126
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0448 0.0817
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.008 0.0115
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0009 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Schistosoma mansoni DNA polymerase eta 0.0021 0.0153 0.019
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0026 0.0198 0.1182
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0271 0.039
Schistosoma mansoni acetylcholine receptor-related 0.0009 0.0015 0.001
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0398 0.051
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0078 0.0778 0.2383
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0266 0.0338
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0042 0.0379 0.6061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0178
Trypanosoma brucei unspecified product 0.0021 0.0153 0.0881
Trypanosoma brucei unspecified product 0.0015 0.0079 0.0386
Echinococcus granulosus Smad4 0.0042 0.0383 0.049
Schistosoma mansoni Smad4 0.0042 0.0383 0.049
Trypanosoma cruzi aldo/keto reductase, putative 0.0144 0.1521 1
Echinococcus granulosus nAChR subunit 0.002 0.0133 0.0164
Brugia malayi hypothetical protein 0.0017 0.01 0.0147
Loa Loa (eye worm) MH2 domain-containing protein 0.0618 0.6796 0.979
Onchocerca volvulus 0.0014 0.0075 0.0125
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0266 0.0383
Plasmodium vivax transportin, putative 0.0011 0.0038 0.0294
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.018 0.0194
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0266 0.0392
Brugia malayi Smad1 0.0042 0.0383 0.0563
Loa Loa (eye worm) nuclear factor I 0.0023 0.0173 0.0249
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0123 0.0178
Onchocerca volvulus 0.002 0.0133 0.0234
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0383 0.049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.008 0.0095
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0266 0.0259
Trypanosoma cruzi aldo/keto reductase, putative 0.0042 0.0379 0.2389
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Plasmodium falciparum aldo-keto reductase, putative 0.0042 0.0379 0.6501
Brugia malayi Integrin alpha pat-2 precursor 0.0062 0.0605 0.089
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.1001 0.1297
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0094 0.0087
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0123 0.1287 0.8181
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0067
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0133 0.0126
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0044 0.042
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0811 0.1193
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0246 0.1499
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Schistosoma mansoni hypothetical protein 0.0081 0.0811 0.1049
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0015 0.0022
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0153 0.019
Schistosoma mansoni methylthioadenosine phosphorylase 0.0026 0.0198 0.0249
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0047 0.0069
Schistosoma mansoni acetylcholine receptor subunit beta 0.0009 0.0015 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Echinococcus multilocularis neuropeptide receptor A26 0.0473 0.5178 0.5175
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0009 0.0015 0.0022
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0032 0.0047
Plasmodium vivax SET domain protein, putative 0.0063 0.0612 1
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0153 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0266 0.0392
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0011 0.0032 0.0047
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Brugia malayi Nuclear hormone receptor E75 0.0015 0.008 0.0118
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.008 0.0135
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0433 0.4735 0.6822
Brugia malayi hypothetical protein 0.0009 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0061
Brugia malayi Pre-SET motif family protein 0.0063 0.0612 0.0901
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0455 0.2895
Brugia malayi MH2 domain containing protein 0.0019 0.0123 0.0182
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.008 0.0115
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Loa Loa (eye worm) hypothetical protein 0.0063 0.0612 0.0882
Trypanosoma brucei aldo-keto reductase, putative 0.0144 0.1521 1
Brugia malayi PHD-finger family protein 0.0012 0.0043 0.0063
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0009 0.0015 0.001
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0123 0.0215
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.002 0.0133 0.0196
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0266 0.0392
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0047 0.0171
Echinococcus granulosus lamin dm0 0.0014 0.0075 0.0088
Loa Loa (eye worm) integrin alpha pat-2 0.0137 0.1439 0.2073
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0153 0.0881
Schistosoma mansoni smad 0.0019 0.0123 0.0152
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0009 0.0015 0.0022
Onchocerca volvulus 0.0009 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0059 0.0572 0.0824
Brugia malayi Importin beta-1 subunit 0.0059 0.0572 0.0842
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0022 0.0009
Brugia malayi Cation transporter family protein 0.002 0.0133 0.0196
Brugia malayi jmjC domain containing protein 0.001 0.0021 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0336 0.0484
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.002 0.0133 0.0164
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0078 0.0778 0.5048
Brugia malayi hypothetical protein 0.0009 0.0015 0.0022
Brugia malayi ecdysteroid receptor 0.0032 0.0266 0.0392
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Trichomonas vaginalis hypothetical protein 0.0011 0.0038 0.0058
Onchocerca volvulus Alhambra homolog 0.003 0.0246 0.0442
Loa Loa (eye worm) hypothetical protein 0.0174 0.1852 0.2668
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0015 0.0022
Brugia malayi hypothetical protein 0.0009 0.0015 0.0022
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0572 0.3675
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.008 0.0095
Echinococcus multilocularis purine nucleoside phosphorylase 0.0123 0.1287 0.1281
Echinococcus granulosus lysine specific demethylase 6a 0.001 0.0021 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0192 0.1143
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0144 0.1521 1
Loa Loa (eye worm) Smad1 0.0042 0.0383 0.0551
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0246 0.0354
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.2087 0.2714
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.2087 0.2714
Echinococcus granulosus voltage gated potassium channel subunit 0.0042 0.0379 0.0485
Echinococcus granulosus integrin alpha 3 0.003 0.0245 0.031
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0153 0.0221
Echinococcus multilocularis translational activator gcn1 0.0011 0.0038 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0612 0.0789
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0627 0.0808
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0398 0.0574
Echinococcus multilocularis bloom syndrome protein 0.0012 0.0047 0.0039
Entamoeba histolytica Ran family GTPase 0.0044 0.0398 0.1209
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0144 0.1521 0.2806
Schistosoma mansoni ran 0.0044 0.0398 0.051
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0591
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0266 0.048
Onchocerca volvulus 0.0032 0.0271 0.0489
Brugia malayi hypothetical protein 0.0017 0.01 0.0147
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0784 0.1013
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.008 0.0095
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0266 0.0259
Toxoplasma gondii aldose reductase, putative 0.0144 0.1521 1
Schistosoma mansoni hypothetical protein 0.0174 0.1852 0.2407
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0455 0.2895
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0591
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0133 0.0164
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.008 0.0118
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0133 0.0164
Echinococcus multilocularis aldo keto reductase 0.0144 0.1521 0.1514
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0026 0.0198 0.0475
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0266 0.0259
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0153 0.0881
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0379 0.069
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0266 0.0392
Onchocerca volvulus 0.0063 0.0612 0.1122
Plasmodium falciparum phd finger protein, putative 0.003 0.0246 0.4078
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0022 0.0009
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.086 0.1113
Schistosoma mansoni hypothetical protein 0.0081 0.0811 0.1049
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0612 0.0789
Schistosoma mansoni cpg binding protein 0.0032 0.0271 0.0344
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0383 0.0551
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.008 0.0073
Echinococcus multilocularis purine nucleoside phosphorylase 0.0123 0.1287 0.1281
Loa Loa (eye worm) hypothetical protein 0.0032 0.0273 0.0394
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0572 0.3675
Trichomonas vaginalis ran, putative 0.0044 0.0398 0.0725
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0047 0.0073
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.002 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0153 0.0221
Echinococcus multilocularis lysine specific demethylase 6a 0.001 0.0021 0.0014
Echinococcus granulosus phd:f box containing protein 0.001 0.0021 0.0018
Echinococcus multilocularis cpg binding protein 0.0034 0.0291 0.0284
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0047 0.0069
Trichomonas vaginalis DNA helicase recq1, putative 0.0012 0.0047 0.0073
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0026 0.0198 0.1182
Brugia malayi nuclear receptor NHR-67 0.0015 0.008 0.0118
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0009 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0398 0.0586
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0612 0.0789
Onchocerca volvulus 0.0009 0.0015 0.0015
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0078 0.0778 0.0771
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0266 0.0383
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0021 0.0018
Trichomonas vaginalis aldo-keto reductase, putative 0.0042 0.0379 0.069
Echinococcus multilocularis aldehyde reductase 0.0102 0.1055 0.1049
Mycobacterium tuberculosis Conserved protein 0.0042 0.0379 0.1975
Echinococcus multilocularis dna polymerase eta 0.0021 0.0153 0.0146
Plasmodium vivax importin-beta 2, putative 0.0059 0.0572 0.9323
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0266 0.0338
Onchocerca volvulus 0.0144 0.1521 0.2806
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Schistosoma mansoni smad1 5 8 and 0.0042 0.0383 0.049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0153 0.0411
Loa Loa (eye worm) hypothetical protein 0.0085 0.086 0.1239
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0123 0.1287 0.8145
Brugia malayi nuclear receptor NHR-88 0.0015 0.008 0.0118
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.01 0.0093
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Giardia lamblia UPL-1 0.0026 0.0198 0.0475
Schistosoma mansoni Smad4 0.0019 0.0123 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0266 0.0392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0028 0.0027
Echinococcus granulosus JmjC domain containing protein 4 0.001 0.0021 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0136 0.0169
Loa Loa (eye worm) hypothetical protein 0.0014 0.0072 0.0103
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.008 0.0095
Giardia lamblia DINP protein human, muc B family 0.0021 0.0153 0.0333
Echinococcus multilocularis purine nucleoside phosphorylase 0.0123 0.1287 0.1281
Schistosoma mansoni purine nucleoside phosphorylase 0.0123 0.1287 0.167
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.041 0.1138
Brugia malayi MH1 domain containing protein 0.0023 0.0173 0.0255
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0266 0.0338
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0266 0.0383
Schistosoma mansoni potassium channel beta 0.0042 0.0379 0.0485
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0094 0.0485
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0266 0.0338
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0008 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0075 0.0108
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.002 0.0133 0.0164
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0133 0.0164
Onchocerca volvulus 0.0144 0.1521 0.2806
Loa Loa (eye worm) RecQ helicase 0.0012 0.0047 0.0067
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0811 0.1168
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Schistosoma mansoni pol-related 0.0144 0.1521 0.1975
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Echinococcus granulosus translational activator gcn1 0.0011 0.0038 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0266 0.0383
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.0144
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.002 0.0133 0.0192
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0376 0.0369
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0133 0.0196
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0266 0.048
Brugia malayi NADH-dependent xylose reductase 0.0042 0.0379 0.0558
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0266 0.0338
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0094 0.0087
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0133 0.0164
Echinococcus multilocularis lamin dm0 0.0014 0.0075 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0266 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0079 0.0386
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0811 0.0804
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0133 0.0196
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0599 0.0863
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0354
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.01 0.0121
Schistosoma mansoni aldo-keto reductase 0.0144 0.1521 0.1975
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0627 0.062
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0579 0.0746
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0026 0.0198 0.1182
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.0881
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0153 0.0881
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0078 0.0778 0.5048
Loa Loa (eye worm) GABA receptor subunit 0.0011 0.0032 0.0046
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0266 0.0338
Loa Loa (eye worm) ACC-1 protein 0.002 0.0133 0.0192
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0094 0.132
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.018 0.1061
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0144 0.1521 0.2238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0266 0.0259
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0032 0.0047
Echinococcus granulosus aldo keto reductase 0.0144 0.1521 0.1975
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.086 0.1113
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0028 0.0021
Echinococcus granulosus dna polymerase kappa 0.0021 0.0153 0.019
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0078 0.0778 0.1121
Echinococcus granulosus purine nucleoside phosphorylase 0.0123 0.1287 0.167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.2087 0.2714
Brugia malayi jmjC domain containing protein 0.001 0.0021 0.0031
Echinococcus multilocularis uridine phosphorylase 1 0.0026 0.0198 0.0191
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Brugia malayi AF-10 protein 0.001 0.0022 0.0033
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0008 0.0007 0.0011
Onchocerca volvulus 0.0144 0.1521 0.2806
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0398 0.2516
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0047 0.0171
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0572 0.3675
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.002 0.0133 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0266 0.0392
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.018 0.0597
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0133 0.0196
Trypanosoma brucei aldo/keto reductase, putative 0.0042 0.0379 0.2389
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0094 0.0485
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0255 0.2749 0.4046
Schistosoma mansoni lamin 0.0014 0.0075 0.0088
Onchocerca volvulus 0.0011 0.0032 0.0046
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Onchocerca volvulus 0.0011 0.0032 0.0046
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.0414 0.0407
Loa Loa (eye worm) histone methyltransferase 0.0012 0.005 0.0072
Brugia malayi hypothetical protein 0.0015 0.008 0.0118
Echinococcus multilocularis Smad4 0.0042 0.0383 0.0376
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.002 0.0133 0.0196
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0811 0.1049
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0133 0.0196
Entamoeba histolytica alcohol dehydrogenase, putative 0.0042 0.0379 0.115
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0026 0.0198 0.0475
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0026 0.0198 0.0723
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.002 0.0133 0.0196
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.086 0.1266
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0336 0.0429
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0105 0.108 0.1589
Brugia malayi intermediate filament protein 0.0014 0.0075 0.011
Entamoeba histolytica hypothetical protein 0.0026 0.0198 0.0591
Echinococcus multilocularis neuropeptide s receptor 0.0473 0.5178 0.5175
Brugia malayi isocitrate dehydrogenase 0.0016 0.0094 0.0138
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0612 0.3942
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0784 0.0777
Loa Loa (eye worm) hypothetical protein 0.002 0.0133 0.0192
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0627 0.4039
Mycobacterium leprae Possible oxidoreductase 0.0042 0.0379 0.1465
Onchocerca volvulus 0.002 0.0133 0.0234
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0612 0.0789
Giardia lamblia PHD finger protein 15 0.003 0.0246 0.0623
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0144 0.1521 0.2238
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0246 0.0239
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0022 0.0009
Plasmodium falciparum transportin 0.0011 0.0038 0.0315
Schistosoma mansoni hypothetical protein 0.0011 0.0039 0.0041
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0627 0.0808
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0591
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0198 0.0723
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0266 0.0392
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0153 0.0411
Brugia malayi ecdysone receptor 0.0015 0.008 0.0118
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.008 0.0073
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0094 0.0087
Echinococcus granulosus jumonji domain containing 1A 0.001 0.0021 0.0018
Onchocerca volvulus 0.0105 0.108 0.1989
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0038 0.0055
Schistosoma mansoni intermediate filament proteins 0.0014 0.0075 0.0088
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.018 0.2691
Schistosoma mansoni uridine phosphorylase 0.0026 0.0198 0.0249
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0266 0.0383
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0266 0.0392
Brugia malayi Bromodomain containing protein 0.0034 0.0291 0.0428
Brugia malayi PHD-finger family protein 0.003 0.0246 0.0362
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.005 0.0043
Trypanosoma brucei uridine phosphorylase 0.0026 0.0198 0.1182
Echinococcus granulosus neuropeptide receptor A26 0.0473 0.5178 0.6747
Plasmodium falciparum aldehyde reductase, putative 0.0042 0.0379 0.6501
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0133 0.0164
Echinococcus multilocularis nAChR subunit 0.0011 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0153 0.0451
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0009 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0098 0.1003 0.1445
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0098 0.1003 0.1299
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0133 0.0196
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0266 0.0338
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0009 0.0015 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0266 0.048
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0133 0.0164
Brugia malayi tailless protein 0.0015 0.008 0.0118
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0133 0.0126
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0115
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.018 0.2886
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Schistosoma mansoni hypothetical protein 0.0105 0.108 0.14
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0811 0.1049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0266 0.0383
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0026 0.0198 0.0325
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0192 0.311
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0133 0.0196
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0133 0.0164
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0123 0.0152
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.041 0.7059
Loa Loa (eye worm) hypothetical protein 0.0105 0.1079 0.1555
Trichomonas vaginalis aldo-keto reductase, putative 0.0042 0.0379 0.069
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.018 0.1061
Loa Loa (eye worm) acetylcholine receptor protein 0.0009 0.0015 0.0022
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0009 0.0015 0.0008
Echinococcus multilocularis snurportin 1 0.0631 0.6941 0.6939
Brugia malayi MH1 domain containing protein 0.0042 0.0383 0.0563
Schistosoma mansoni nAChR subunit 0.002 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.008 0.0118
Trichomonas vaginalis aldo-keto reductase, putative 0.0144 0.1521 0.2806
Brugia malayi MH1 domain containing protein 0.0023 0.0173 0.0255
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0661 0.4269
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.018 0.0194
Schistosoma mansoni neurotransmitter gated ion channel 0.0011 0.0032 0.0032
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.086 0.0854
Echinococcus granulosus GPCR family 2 0.0081 0.0811 0.1049
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0009 0.0015 0.0022
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0133 0.0126
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0116
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0009 0.0015 0.0022
Brugia malayi excitatory GABA receptor EXP-1A 0.002 0.0133 0.0196
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0133 0.0196
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0398 0.2516
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0198 0.0354
Brugia malayi Intermediate filament tail domain containing protein 0.0014 0.0075 0.011
Loa Loa (eye worm) oxidoreductase 0.0144 0.1521 0.2191
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0012 0.0047 0.0466
Echinococcus granulosus histone acetyltransferase KAT2B 0.0161 0.1703 0.2212
Schistosoma mansoni Smad4 0.0019 0.0123 0.0152
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0123 0.1287 0.3883
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0153 0.0881
Echinococcus granulosus methylthioadenosine phosphorylase 0.0026 0.0198 0.0249
Onchocerca volvulus Putative nachr subunit 0.002 0.0133 0.0234
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0133 0.0164
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0123 0.0182
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0008 0.0007 0.001
Entamoeba histolytica aldose reductase, putative 0.0144 0.1521 0.468
Schistosoma mansoni uridine phosphorylase 0.0026 0.0198 0.0249
Loa Loa (eye worm) hypothetical protein 0.0032 0.0266 0.0383
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.002 0.0133 0.0196
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0144 0.1521 0.1975
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0042 0.0379 0.2389
Schistosoma mansoni nuclear hormone receptor 0.0015 0.008 0.0095
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0026 0.0198 0.0059
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.0144
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0144 0.1521 0.1514
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0123 0.0178
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.002 0.0133 0.0126
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0021 0.003
Mycobacterium tuberculosis Probable oxidoreductase 0.0144 0.1521 0.9871
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0133 0.0126
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.1852 0.2725
Brugia malayi acetyltransferase, GNAT family protein 0.0165 0.1755 0.2582
Onchocerca volvulus 0.0085 0.086 0.1582
Onchocerca volvulus 0.0015 0.008 0.0135
Echinococcus multilocularis peregrin 0.0034 0.0291 0.0284
Echinococcus multilocularis geminin 0.0697 0.7672 0.767
Loa Loa (eye worm) hypothetical protein 0.0081 0.0811 0.1168
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.3241 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0133 0.0196
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.008 0.0073
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0455 0.0584
Schistosoma mansoni DNA helicase recq1 0.0012 0.0047 0.0051
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0165 0.1755 0.1749
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0008 0.0007 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0448 0.0817
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.3241 0.5996
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.2087 0.2082
Echinococcus granulosus importin subunit beta 1 0.0059 0.0572 0.0737
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0398 0.6383
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0078 0.0778 0.1006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.008 0.0095
Schistosoma mansoni smad1 5 8 and 0.0042 0.0383 0.049
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0777 0.1005
Plasmodium vivax aldehyde reductase, putative 0.0042 0.0379 0.6061
Entamoeba histolytica aldose reductase, putative 0.0144 0.1521 0.468
Loa Loa (eye worm) LGC-31 protein 0.002 0.0133 0.0192
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0038 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0266 0.0338
Brugia malayi hypothetical protein 0.0025 0.0192 0.0283
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0266 0.0392
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0144 0.1521 0.2191
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0153 0.0881
Loa Loa (eye worm) uridine phosphorylase 0.0026 0.0198 0.0286
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0014 0.0075 0.0108
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0026 0.0198 0.0591
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0246 0.0311
Loa Loa (eye worm) hypothetical protein 0.0023 0.0173 0.0249
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0246 0.0311
Echinococcus granulosus integrin alpha ps 0.003 0.0245 0.031
Brugia malayi steroid hormone receptor 0.0032 0.0266 0.0392
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0383 0.049
Schistosoma mansoni nuclear receptor 0.0015 0.008 0.0095
Schistosoma mansoni hypothetical protein 0.003 0.0246 0.0311
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0266 0.0338
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0039 0.0041
Schistosoma mansoni hypothetical protein 0.003 0.0245 0.031
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0123 0.0152
Loa Loa (eye worm) oxidoreductase 0.0144 0.1521 0.2191
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0811 0.1193
Loa Loa (eye worm) oxidoreductase 0.0144 0.1521 0.2191
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0383 0.0551
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0266 0.0392
Loa Loa (eye worm) transcription factor SMAD2 0.0618 0.6796 0.979
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.008 0.0095
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0094 0.0485
Echinococcus multilocularis purine nucleoside phosphorylase 0.0123 0.1287 0.1281
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0198 0.0354
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.008 0.0073
Toxoplasma gondii Purine nucleoside phosphorylase 0.0026 0.0198 0.1182
Loa Loa (eye worm) ACC-1 protein 0.002 0.0133 0.0192

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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