Detailed information for compound 1162289

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 193.226 | Formula: C8H7N3OS
  • H donors: 1 H acceptors: 1 LogP: 0.06 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1NC2=Nc3c(CN2C1)scc3
  • InChi: 1S/C8H7N3OS/c12-7-4-11-3-6-5(1-2-13-6)9-8(11)10-7/h1-2H,3-4H2,(H,9,10,12)
  • InChiKey: HQIKGLILESJKMU-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide receptor 0.0018 0.016 0.016
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0127 0.0419
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0211 0.1186
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0115 0.1457 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0021 0.0021
Trypanosoma brucei glycerol uptake protein, putative 0.0029 0.0306 0.1948
Brugia malayi neuropeptide F receptor 0.0018 0.016 0.0391
Schistosoma mansoni cpg binding protein 0.0056 0.0665 0.0665
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0436 0.1457
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0227
Plasmodium vivax hypothetical protein, conserved 0.0104 0.131 1
Schistosoma mansoni hypothetical protein 0.0029 0.0306 0.0306
Echinococcus multilocularis survival motor neuron protein 1 0.0274 0.3575 0.3561
Brugia malayi Ets-domain containing protein 0.001 0.0051 0.0087
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0029 0.0306 0.2074
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0013 0.0088 0.0067
Echinococcus granulosus cpg binding protein 0.0056 0.0665 0.0646
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0436 0.1457
Plasmodium falciparum cysteine repeat modular protein 1 0.0019 0.0167 0.1273
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0029 0.0306 0.0286
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Echinococcus granulosus g protein coupled receptor 0.0018 0.016 0.0139
Schistosoma mansoni ets-related 0.001 0.0051 0.0051
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0436 0.1457
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0029 0.0306 0.0306
Brugia malayi cytochrome P450 0.0014 0.0098 0.0219
Echinococcus multilocularis g protein coupled receptor 0.0018 0.016 0.0139
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0011 0.0059 0.0222
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.011 0.1437
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0029 0.0306 0.0286
Schistosoma mansoni gabp alpha 0.007 0.0847 0.0847
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.016 0.0139
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.016 0.016
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Brugia malayi sulfakinin receptor protein 0.0018 0.016 0.0391
Brugia malayi Pre-SET motif family protein 0.003 0.0315 0.0829
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.016 0.0391
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0011 0.0059 0.0222
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.016 0.0255
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis lamin 0.0031 0.0334 0.0314
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0021 0.0021
Echinococcus granulosus fmrfamide receptor 0.0018 0.016 0.0139
Leishmania major glycosyl hydrolase-like protein 0.0014 0.011 0.0376
Schistosoma mansoni lamin 0.0031 0.0334 0.0334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0021 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0018 0.016 0.0139
Chlamydia trachomatis endonuclease IV 0.0074 0.0901 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0077 0.025
Onchocerca volvulus 0.0229 0.2976 1
Brugia malayi follicle stimulating hormone receptor 0.0239 0.3115 0.8705
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Giardia lamblia Hypothetical protein 0.0013 0.0088 0.0448
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.016 0.016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0017 0.0139 0.1812
Schistosoma mansoni hypothetical protein 0.0754 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0017 0.0139 0.0118
Trypanosoma brucei glycerol uptake protein, putative 0.0029 0.0306 0.1948
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0139 0.0458
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0239 0.3115 0.5669
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0077 0.025
Schistosoma mansoni lamin 0.0031 0.0334 0.0334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0315 0.0295
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0008 0.003 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0018 0.016 0.0139
Echinococcus granulosus intermediate filament protein 0.0031 0.0334 0.0314
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Leishmania major metacaspase, putative 0.0104 0.131 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0103 0.015
Trypanosoma cruzi metacaspase 5, putative 0.0104 0.131 1
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.131 0.4401
Loa Loa (eye worm) hypothetical protein 0.0019 0.0175 0.0284
Echinococcus multilocularis serotonin receptor 0.0018 0.016 0.0139
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0051 0.0031
Brugia malayi Serotonin receptor 0.0018 0.016 0.0391
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0051 0.0031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0071
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.016 0.0139
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Loa Loa (eye worm) histone methyltransferase 0.0017 0.015 0.0236
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0436 0.2988
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0901 0.6876
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.016 0.0255
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0309 0.4042 0.403
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.011 0.0361
Schistosoma mansoni hypothetical protein 0.005 0.0581 0.0581
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.016 0.0139
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus granulosus sterol O acyltransferase 1 0.0298 0.3904 0.3891
Loa Loa (eye worm) hypothetical protein 0.0008 0.003 0.0016
Echinococcus multilocularis tissue type plasminogen activator 0.0019 0.0167 0.0147
Plasmodium falciparum plasmepsin II 0.0011 0.0059 0.0451
Toxoplasma gondii hypothetical protein 0.0029 0.0306 0.2074
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.016 0.016
Echinococcus granulosus protein C ets 2 0.001 0.0051 0.0031
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0127 0.0211
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0334 0.0574
Echinococcus multilocularis caspase 8 0.0104 0.131 0.1292
Plasmodium vivax metacaspase 1, putative 0.0104 0.131 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.016 0.0139
Echinococcus granulosus hypothetical protein 0.0018 0.016 0.0139
Mycobacterium tuberculosis Probable oxidoreductase 0.0115 0.1457 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.016 0.0139
Loa Loa (eye worm) cytochrome P450 0.0014 0.0098 0.0142
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.016 0.016
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0157 0.12
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis neuropeptide receptor 0.0018 0.016 0.0139
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0013 0.0088 0.0188
Toxoplasma gondii thioredoxin reductase 0.0045 0.0524 0.3709
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0063 0.0764 0.0745
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.016 0.016
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.011 0.0361
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2975 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0029 0.0306 0.0306
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0045 0.0524 0.3133
Schistosoma mansoni ets 0.001 0.0051 0.0051
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0101 0.0081
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0008 0.003 0.0016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.131 0.4401
Schistosoma mansoni hypothetical protein 0.001 0.0051 0.0051
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0008 0.003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0326 0.056
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0008 0.003 0.00000000038671
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Loa Loa (eye worm) MBOAT family protein 0.0029 0.0306 0.0523
Entamoeba histolytica hypothetical protein 0.0029 0.0306 0.4002
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0104 0.131 0.3629
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.016 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0315 0.0315
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0101 0.0272
Loa Loa (eye worm) hypothetical protein 0.0269 0.3514 0.6401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0008 0.003 0.0025
Echinococcus multilocularis somatostatin receptor 0.0018 0.016 0.0139
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0051 0.0031
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0029 0.0306 0.4002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.01 0.0525
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0306 0.1021
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0051 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Toxoplasma gondii kringle domain-containing protein 0.0019 0.0167 0.103
Loa Loa (eye worm) hypothetical protein 0.0104 0.131 0.2363
Loa Loa (eye worm) hypothetical protein 0.003 0.0315 0.054
Toxoplasma gondii aspartyl protease ASP3 0.0011 0.0059 0.0222
Onchocerca volvulus 0.0018 0.016 0.047
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0021 0.0021
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0211 0.1402
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.016 0.016
Trichomonas vaginalis helicase, putative 0.0012 0.0077 0.025
Echinococcus granulosus g-protein coupled receptor 0.0018 0.016 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Trypanosoma brucei glucosidase, putative 0.0039 0.0436 0.2988
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0101 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Brugia malayi Pepsin A precursor 0.0011 0.0059 0.0108
Onchocerca volvulus 0.0018 0.016 0.047
Brugia malayi hypothetical protein 0.0011 0.0059 0.0108
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0029 0.0306 0.2074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.016 0.0139
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.016 0.0139
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0029 0.0306 0.0306
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0008 0.003 0.0226
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0191 0.0633
Trypanosoma cruzi metacaspase, putative 0.0104 0.131 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.016 0.0139
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0309 0.4042 0.403
Echinococcus granulosus somatostatin receptor 0.0018 0.016 0.0139
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.016 0.0139
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Plasmodium falciparum plasmepsin IX 0.0011 0.0059 0.0451
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0063 0.0764 0.2093
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.016 0.0139
Brugia malayi Uncoordinated protein 44 0.0014 0.0101 0.0227
Plasmodium vivax SET domain protein, putative 0.003 0.0315 0.2048
Loa Loa (eye worm) glutathione reductase 0.0045 0.0524 0.0922
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.016 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0315 0.0315
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0105 0.1322 0.1304
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.1302 0.8862
Trypanosoma cruzi GUP1, putative 0.0029 0.0306 0.1948
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0127 0.0513
Trypanosoma cruzi glycerol uptake protein, putative 0.0029 0.0306 0.1948
Brugia malayi Cell death protein 3 precursor 0.0104 0.131 0.3629
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.016 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0029 0.0306 0.0523
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0106 0.0086
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0088 0.0198
Schistosoma mansoni alpha-glucosidase 0.0151 0.1931 0.1931
Schistosoma mansoni caspase-7 (C14 family) 0.0309 0.4042 0.4042
Onchocerca volvulus 0.0031 0.0334 0.1059
Brugia malayi Kringle domain containing protein 0.0019 0.0167 0.0411
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0127 0.0299
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0063 0.0764 0.5623
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.1302 0.8862
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0115 0.1457 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Brugia malayi Death domain containing protein 0.0014 0.0101 0.0227
Echinococcus granulosus thioredoxin glutathione reductase 0.0045 0.0524 0.0504
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Trichomonas vaginalis porcupine, putative 0.0029 0.0306 0.1021
Brugia malayi MBOAT family protein 0.0029 0.0306 0.0803
Loa Loa (eye worm) hypothetical protein 0.0298 0.3904 0.7115
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0105 0.1322 0.1304
Trypanosoma cruzi glycerol uptake protein, putative 0.0029 0.0306 0.1948
Brugia malayi diacylglycerol acyltransferase 0.0029 0.0306 0.0803
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0175 0.0568
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0051 0.0031
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0106 0.0086
Mycobacterium ulcerans endonuclease IV 0.0074 0.0901 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0008 0.003 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0524 0.3695
Plasmodium falciparum plasmepsin X 0.0011 0.0059 0.0451
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0017 0.0139 0.0501
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.016 0.0391
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0668
Brugia malayi intermediate filament protein 0.0031 0.0334 0.0881
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Echinococcus multilocularis musashi 0.0031 0.0334 0.0314
Schistosoma mansoni alpha-glucosidase 0.0151 0.1931 0.1931
Schistosoma mansoni hypothetical protein 0.0014 0.0098 0.0098
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0051 0.0031
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0127 0.0357
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0051 0.0051
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Schistosoma mansoni hypothetical protein 0.001 0.0051 0.0051
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0013 0.0088 0.0188
Leishmania major glycerol uptake protein, putative 0.0029 0.0306 0.1948
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.016 0.0139
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni biogenic amine receptor 0.0018 0.016 0.016
Schistosoma mansoni cytochrome P450 0.0014 0.0098 0.0098
Leishmania major trypanothione reductase 0.0045 0.0524 0.3695
Loa Loa (eye worm) RecQ helicase 0.0021 0.0191 0.0311
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.0139 0.0606
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0102 0.0341
Schistosoma mansoni microtubule-associated protein tau 0.0663 0.8781 0.8781
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0013 0.0088 0.0198
Mycobacterium tuberculosis Probable reductase 0.0104 0.1302 0.8862
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0077 0.025
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0029 0.0306 0.0306
Echinococcus granulosus orexin receptor type 2 0.0018 0.016 0.0139
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.1111 0.1093
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.016 0.016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.1111 0.1093
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0127 0.0513
Echinococcus multilocularis ets variant gene 4 0.001 0.0051 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0127 0.0513
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Loa Loa (eye worm) hypothetical protein 0.0016 0.0135 0.021
Treponema pallidum alginate O-acetylation protein (algI) 0.0029 0.0306 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0077 0.025
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0719 0.9522 0.9521
Brugia malayi Pre-SET motif family protein 0.0201 0.2605 0.7273
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.016 0.0139
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.1302 0.8862
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.011 0.0361
Echinococcus multilocularis protein C ets 2 0.001 0.0051 0.0031
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0029 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0098 0.0284
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0063 0.0764 0.5623
Plasmodium falciparum thioredoxin reductase 0.0016 0.0127 0.0969
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0274 0.3575 0.6512
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.011 0.0361
Leishmania major cAMP-specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0127 0.0107
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Schistosoma mansoni elf1 0.001 0.0051 0.0051
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0019 0.0175 0.0435
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.016 0.0139
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0071
Brugia malayi GnHR receptor homolog 0.0018 0.016 0.0391
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.016 0.0139
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus multilocularis sex peptide receptor 0.0018 0.016 0.0139
Brugia malayi Protein kinase domain containing protein 0.0019 0.0167 0.0411
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Brugia malayi Ets-domain containing protein 0.007 0.0847 0.2324
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0088 0.0198
Echinococcus multilocularis neuropeptide receptor 0.0018 0.016 0.0139
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0008 0.003 0.0009
Toxoplasma gondii aspartyl protease 0.0011 0.0059 0.0222
Echinococcus multilocularis caspase 0.0309 0.4042 0.403
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0127 0.073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.014 0.0336
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.016 0.0255
Echinococcus multilocularis caspase 3 0.0204 0.2648 0.2633
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0013 0.0088 0.0668
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.011 0.0361
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0051 0.0031
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0029 0.0306 0.0286
Plasmodium vivax glutathione reductase, putative 0.0045 0.0524 0.3714
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0104 0.131 0.9612
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.131 0.4401
Echinococcus granulosus neuropeptide s receptor 0.0018 0.016 0.0139
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.016 0.0391
Brugia malayi Cytochrome P450 family protein 0.0022 0.0211 0.0535
Brugia malayi Cytochrome P450 family protein 0.0014 0.0098 0.0219
Schistosoma mansoni cathepsin D (A01 family) 0.0011 0.0059 0.0059
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.016 0.0139
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0029 0.0306 0.0286
Echinococcus multilocularis cpg binding protein 0.0056 0.0665 0.0646
Loa Loa (eye worm) hypothetical protein 0.0013 0.0088 0.0123
Onchocerca volvulus 0.0018 0.016 0.047
Schistosoma mansoni caspase-7 (C14 family) 0.0104 0.131 0.131
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0088 0.0286
Schistosoma mansoni amine GPCR 0.0018 0.016 0.016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Schistosoma mansoni biogenic amine receptor 0.0018 0.016 0.016
Brugia malayi G-protein coupled receptor 0.0018 0.016 0.0391
Loa Loa (eye worm) hypothetical protein 0.0014 0.011 0.0163
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0011 0.0059 0.0039
Mycobacterium ulcerans epimerase 0.0019 0.0175 0.096
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.0139 0.1057
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.016 0.0139
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0013 0.0088 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0088 0.0198
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0211 0.0349
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.016 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0019 0.0167 0.0861
Schistosoma mansoni memapsin-2 (A01 family) 0.0266 0.3469 0.3469
Schistosoma mansoni opsin-like receptor 0.0018 0.016 0.016
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Loa Loa (eye worm) hypothetical protein 0.0014 0.011 0.0164
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0127 0.0513
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0017 0.0139 0.0216
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.011 0.0376
Schistosoma mansoni hypothetical protein 0.0019 0.0167 0.0167
Echinococcus multilocularis serotonin receptor 0.0018 0.016 0.0139
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0098 0.0078
Schistosoma mansoni neuropeptide receptor 0.0018 0.016 0.016
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0013 0.0088 0.0067
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0092 0.1151 0.3181
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.016 0.0391
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0021 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0018 0.016 0.0139
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0013 0.0088 0.0067
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0118 0.0097
Brugia malayi exodeoxyribonuclease III family protein 0.0017 0.0139 0.0332
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.016 0.016
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0051 0.0031
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.016 0.0139
Onchocerca volvulus 0.0018 0.016 0.047
Schistosoma mansoni ap endonuclease 0.0017 0.0139 0.0139
Brugia malayi Fli-1 protein 0.0211 0.2741 0.7653
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.016 0.0139
Loa Loa (eye worm) hhat protein 0.0029 0.0306 0.0523
Schistosoma mansoni hypothetical protein 0.0014 0.0101 0.0101
Brugia malayi RE15519p 0.0018 0.016 0.0391
Leishmania major glycerol uptake protein, putative 0.0029 0.0306 0.1948
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0029 0.0306 0.0286
Schistosoma mansoni DNA helicase recq5 0.0008 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Plasmodium vivax thioredoxin reductase, putative 0.0045 0.0524 0.3714
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni DNA helicase recq1 0.0008 0.003 0.003
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0227
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0013 0.0088 0.0067
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0436 0.3047
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0127 0.0357
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.016 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0088 0.0286
Echinococcus granulosus serotonin receptor 0.0018 0.016 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0088 0.0286
Trichomonas vaginalis transmembrane protein nessy, putative 0.0029 0.0306 0.1021
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.016 0.016
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0051 0.0056
Brugia malayi Eukaryotic aspartyl protease family protein 0.0011 0.0059 0.0108
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0013 0.0088 0.0188
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0029 0.0306 0.0523
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0416 0.5478 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0063 0.0764 0.1363
Onchocerca volvulus 0.0018 0.016 0.047
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.016 0.047
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.016 0.0255
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0021 0.0021
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0175 0.2256 0.4096
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0051 0.0087
Schistosoma mansoni caspase-3 (C14 family) 0.0309 0.4042 0.4042
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0013 0.0088 0.0198
Echinococcus multilocularis caspase 2 0.0104 0.131 0.1292
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.1111 0.3068
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0436 0.0416
Loa Loa (eye worm) CXXC zinc finger family protein 0.0053 0.0624 0.1106
Onchocerca volvulus 0.0056 0.0663 0.2172
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.016 0.016
Schistosoma mansoni neuropeptide receptor 0.0018 0.016 0.016
Schistosoma mansoni myosin xvIII 0.0018 0.016 0.016
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0436 0.1457
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0013 0.0088 0.0088
Schistosoma mansoni opsin-like receptor 0.0018 0.016 0.016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.1362 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.016 0.016
Echinococcus granulosus neuropeptide receptor 0.0018 0.016 0.0139
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0029 0.0306 0.0286
Brugia malayi neuropeptide F receptor 0.0018 0.016 0.0391
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0315 0.0295
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.2605 0.4736
Brugia malayi Thioredoxin reductase 0.0045 0.0524 0.1416
Toxoplasma gondii aspartyl protease ASP1 0.0011 0.0059 0.0222
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0334 0.0574
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0017 0.0139 0.0606
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0051 0.0031
Echinococcus granulosus geminin 0.0321 0.4205 0.4193
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0013 0.0088 0.0067
Brugia malayi MBOAT family protein 0.0029 0.0306 0.0803
Echinococcus granulosus o acyltransferase membrane bound domain 0.0029 0.0306 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0088 0.0198
Onchocerca volvulus 0.0011 0.0059 0.013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.1111 0.1111
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0008 0.003 0.0025
Trypanosoma brucei trypanothione reductase 0.0045 0.0524 0.3695
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis g protein coupled receptor 0.0018 0.016 0.0139
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Loa Loa (eye worm) hypothetical protein 0.0014 0.011 0.0164
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0029 0.0306 0.0286
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0021 0.0021
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0029 0.0306 0.2335
Echinococcus multilocularis dnaJ subfamily B 0.0754 1 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0013 0.0088 0.0198
Entamoeba histolytica vacuolar protein sorting 26 0.0029 0.0306 0.4002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0032 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.016 0.016
Brugia malayi transcription factor E74 isoform 0.001 0.0051 0.0087
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0847 0.0828
Echinococcus granulosus death domain containing protein 0.0014 0.0101 0.0081
Echinococcus granulosus g protein coupled receptor 0.0018 0.016 0.0139
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0227
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0071 0.0142
Echinococcus granulosus lamin dm0 0.0031 0.0334 0.0314
Brugia malayi Serotonin receptor 0.0018 0.016 0.0391
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Plasmodium falciparum phosphodiesterase gamma, putative 0.0013 0.0088 0.0668
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Loa Loa (eye worm) fli-1 protein 0.0211 0.2741 0.4984
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.1111 0.1998
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0663 0.1806
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.131 0.4401
Plasmodium falciparum plasmepsin V 0.0011 0.0059 0.0451
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0101 0.0081
Loa Loa (eye worm) hypothetical protein 0.0014 0.0101 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.016 0.0139
Plasmodium falciparum metacaspase 1 0.0104 0.131 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0011 0.0059 0.0039
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0847 0.1514
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.015 0.0129
Loa Loa (eye worm) hypothetical protein 0.0008 0.0029 0.0015
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.016 0.0139
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0118 0.0097
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0127 0.0753
Loa Loa (eye worm) hypothetical protein 0.0029 0.0306 0.0523
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0668
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.016 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.016 0.0139
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.1111 0.1093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.016 0.016
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0017 0.0139 0.0606
Loa Loa (eye worm) hypothetical protein 0.0029 0.0306 0.0523
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0077 0.025
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0191 0.0633
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0127 0.0542
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Leishmania major cytochrome p450-like protein 0.0022 0.0211 0.1186
Brugia malayi larval opioid receptor 0.0018 0.016 0.0391
Loa Loa (eye worm) hypothetical protein 0.0013 0.0088 0.0123
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0071 0.0142
Echinococcus multilocularis 0.0014 0.0098 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.131 0.4401
Brugia malayi G protein-coupled receptor 0.0018 0.016 0.0391
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.1111 0.1111
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Echinococcus multilocularis geminin 0.0321 0.4205 0.4193
Plasmodium falciparum glutathione reductase 0.0045 0.0524 0.3998
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0077 0.025
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0029 0.0306 0.0306
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0021 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0436 0.1457
Loa Loa (eye worm) thioredoxin reductase 0.0045 0.0524 0.0922
Leishmania major hypothetical protein, conserved 0.0029 0.0306 0.1948
Loa Loa (eye worm) hypothetical protein 0.0019 0.0167 0.0268
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0051 0.0056
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0098 0.0284
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus multilocularis allatostatin A receptor 0.0018 0.016 0.0139
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Brugia malayi aspartic protease BmAsp-1, identical 0.0011 0.0059 0.0108
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0106 0.0086
Schistosoma mansoni ap endonuclease 0.0017 0.0139 0.0139
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0029 0.0306 0.4002
Onchocerca volvulus 0.0018 0.016 0.047
Echinococcus granulosus allatostatin A receptor 0.0018 0.016 0.0139
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0128 0.0735
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.016 0.0391
Plasmodium falciparum phosphodiesterase delta, putative 0.0013 0.0088 0.0668
Brugia malayi G-protein coupled receptor 0.0018 0.016 0.0391
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.016 0.0139
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0063 0.0203
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.2256 0.224
Leishmania major hypothetical protein, conserved 0.0019 0.0167 0.0833
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0029 0.0306 0.0286
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.016 0.0139
Onchocerca volvulus 0.0031 0.0334 0.1059
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0436 0.1457
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0013 0.0088 0.0286
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0127 0.0969
Schistosoma mansoni cathepsin D (A01 family) 0.0011 0.0059 0.0059
Echinococcus granulosus Ankyrin 0.0014 0.0103 0.0082
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0029 0.0306 0.1972
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0013 0.0088 0.0198
Onchocerca volvulus 0.0029 0.0306 0.0965
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0029 0.0306 0.0286
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0088 0.0198
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0436 0.2988
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0436 0.1457
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0191 0.0478
Echinococcus granulosus neuropeptide receptor 0.0018 0.016 0.0139
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0115 0.1457 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Toxoplasma gondii histone lysine methyltransferase SET1 0.0101 0.1272 0.9323
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0063 0.0764 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trypanosoma cruzi glycerol uptake protein, putative 0.0029 0.0306 0.1948
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0286 0.0266
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0127 0.0513
Schistosoma mansoni netrin receptor unc5 0.0014 0.0101 0.0101
Brugia malayi Ets-domain containing protein 0.007 0.0847 0.2324
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0127 0.0513
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0315 0.0315
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.016
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0013 0.0088 0.0123
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0021 0.0021
Echinococcus multilocularis Ankyrin 0.0014 0.0103 0.0082
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0198
Leishmania major glycerol uptake protein, putative 0.0029 0.0306 0.1948
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0103 0.0103
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.016 0.0391
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0013 0.0088 0.0198
Onchocerca volvulus 0.0018 0.016 0.047
Schistosoma mansoni amine GPCR 0.0018 0.016 0.016
Brugia malayi Cytochrome P450 family protein 0.005 0.0589 0.1598
Brugia malayi MBOAT family protein 0.0029 0.0306 0.0803
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.016 0.047
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0017 0.0139 1
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0029 0.0306 0.0286
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0847 0.0828
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0127 0.0513
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0019 0.0175 0.096
Loa Loa (eye worm) TK/ROR protein kinase 0.0019 0.0167 0.0268
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0436 0.076
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0147 0.0355
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0127 0.0357
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0211 0.0349
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0077 0.025
Trypanosoma cruzi metacaspase, putative 0.0104 0.131 1
Echinococcus granulosus caspase 3 0.0204 0.2648 0.2633
Schistosoma mansoni zinc finger protein 0.0029 0.0306 0.0306
Schistosoma mansoni hypothetical protein 0.0056 0.0663 0.0663
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.016 0.0139
Schistosoma mansoni biogenic amine receptor 0.0018 0.016 0.016
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus multilocularis sterol O acyltransferase 1 0.0298 0.3904 0.3891
Onchocerca volvulus Cell death protein 3 homolog 0.0104 0.131 0.4364
Brugia malayi AKH receptor 0.0018 0.016 0.0391
Brugia malayi putative neuropeptide receptor 0.0018 0.016 0.0391
Giardia lamblia hypothetical protein 0.0013 0.0088 0.0448
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Leishmania major hypothetical protein, conserved 0.0013 0.0088 0.0198
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.011 0.0361
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0436 0.57
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0101 0.0081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus multilocularis microtubule associated protein 2 0.0663 0.8781 0.8778
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.016 0.0139
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0017 0.0139 0.0606
Schistosoma mansoni survival motor neuron protein 0.0056 0.0663 0.0663
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.016 0.0139
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0436 0.1457
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.016 0.0391
Brugia malayi CXXC zinc finger family protein 0.0053 0.0624 0.1699
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.016 0.016
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.016 0.0255
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.016 0.0139
Plasmodium falciparum metacaspase-like protein 0.0104 0.131 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.014 0.0219
Onchocerca volvulus 0.0011 0.0059 0.013
Plasmodium falciparum plasmepsin III 0.0011 0.0059 0.0451
Echinococcus granulosus lysosomal alpha glucosidase 0.0175 0.2256 0.224
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0101 0.0081
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.011 0.0302
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0013 0.0088 0.0088
Echinococcus multilocularis thioredoxin glutathione reductase 0.0045 0.0524 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0306 0.1021
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.016 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0021 0.0021
Leishmania major cytochrome p450-like protein 0.0014 0.0098 0.0284
Echinococcus granulosus bloom syndrome protein 0.0021 0.0191 0.017
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.011 0.0251
Onchocerca volvulus 0.0018 0.016 0.047
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0017 0.0139 0.0118
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0021 0.0021
Onchocerca volvulus 0.003 0.0315 0.0997
Loa Loa (eye worm) hypothetical protein 0.0104 0.131 0.2363
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.016 0.0139
Onchocerca volvulus 0.0018 0.016 0.047
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0191 0.017
Loa Loa (eye worm) aspartyl protease 6 0.0011 0.0059 0.0071
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.016 0.0139
Schistosoma mansoni hypothetical protein 0.0321 0.4205 0.4205
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni opsin-like receptor 0.0018 0.016 0.016
Echinococcus granulosus o acyltransferase membrane bound domain 0.0029 0.0306 0.0286
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0211 0.1186
Trypanosoma cruzi metacaspase 5, putative 0.0104 0.131 1
Trypanosoma brucei metacaspase MCA2 0.0104 0.131 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.1302 0.8862
Plasmodium falciparum plasmepsin VIII, putative 0.0011 0.0059 0.0451
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0029 0.0306 0.0286
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0104 0.131 0.9612
Echinococcus granulosus caspase 2 0.0104 0.131 0.1292
Loa Loa (eye worm) MBOAT family protein 0.0029 0.0306 0.0523
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.016 0.0139
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0011 0.0059 0.019
Onchocerca volvulus 0.0018 0.016 0.047
Plasmodium falciparum plasmepsin VII 0.0011 0.0059 0.0451
Onchocerca volvulus 0.0018 0.016 0.047
Loa Loa (eye worm) hypothetical protein 0.0416 0.5478 1
Echinococcus granulosus g protein coupled receptor 0.0018 0.016 0.0139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.1111 0.1111
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.016 0.0255
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.1151 0.1133
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0211 0.1186
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0013 0.0088 0.0067
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0862 0.0844
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0088 0.0198
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0315 0.0295
Schistosoma mansoni amine GPCR 0.0018 0.016 0.016
Echinococcus multilocularis lamin dm0 0.0031 0.0334 0.0314
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0098 0.0515
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0056
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Echinococcus granulosus microtubule associated protein 2 0.0663 0.8781 0.8778
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Brugia malayi Dopamine receptor 0.0018 0.016 0.0391
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0334 0.0881
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0104 0.131 0.9612
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.016 0.0139
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0098 0.0284
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0098 0.0284
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0063 0.0764 0.5623
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0088 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0901 0.2477
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0127 0.0419
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.016 0.016
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0013 0.0088 0.0067
Plasmodium falciparum plasmepsin I 0.0011 0.0059 0.0451
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0127 0.0107
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0139 0.0458
Schistosoma mansoni adenoreceptor 0.0018 0.016 0.016
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0167 0.0833
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0011 0.0059 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.016 0.0391
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Trypanosoma cruzi metacaspase, putative 0.0104 0.131 1
Plasmodium vivax phosphodiesterase gamma, putative 0.0013 0.0088 0.0227
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0105 0.1322 0.1322
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0003 0.00000000015697
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0063 0.0764 0.5623
Schistosoma mansoni ets-related 0.0211 0.2741 0.2741
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0175 0.0568
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.011 0.0376
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Trypanosoma brucei metacaspase 0.0104 0.131 1
Brugia malayi Dopamine receptor protein 2 0.0018 0.016 0.0391
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0104 0.131 0.131
Trypanosoma brucei Metacaspase-4 0.0104 0.131 1
Echinococcus granulosus lamin 0.0031 0.0334 0.0314
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Onchocerca volvulus 0.0118 0.1488 0.4965
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0306 0.1021
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.1302 0.8862
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0013 0.0088 0.0067
Trypanosoma cruzi metacaspase, putative 0.0104 0.131 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0198
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.016 0.0139
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0436 0.2988
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0211 0.0349
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.016 0.016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0077 0.025
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0306 0.4002
Onchocerca volvulus 0.0018 0.016 0.047
Schistosoma mansoni amine GPCR 0.0018 0.016 0.016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.016 0.0139
Echinococcus multilocularis orexin receptor type 2 0.0018 0.016 0.0139
Brugia malayi Melatonin receptor type 1A 0.0018 0.016 0.0391
Loa Loa (eye worm) PDE1B protein 0.0013 0.0088 0.0123
Loa Loa (eye worm) hypothetical protein 0.0244 0.3178 0.5785
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0013 0.0088 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.131 0.4401
Echinococcus granulosus survival motor neuron protein 1 0.0274 0.3575 0.3561
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0436 0.57
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.1302 0.8862
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0901 0.591
Echinococcus granulosus caspase 0.0309 0.4042 0.403
Schistosoma mansoni intermediate filament proteins 0.0031 0.0334 0.0334
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0051 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.131 0.4401
Leishmania major glycerol uptake protein, putative 0.0029 0.0306 0.1948
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0105 0.1322 0.1304
Toxoplasma gondii exonuclease III APE 0.0017 0.0139 0.0817
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.016 0.016
Brugia malayi MBOAT family protein 0.0029 0.0306 0.0803
Echinococcus granulosus o acyltransferase membrane bound domain 0.0029 0.0306 0.0286
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.016 0.0139
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0051 0.0031
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0013 0.0088 0.0067
Brugia malayi hypothetical protein 0.0011 0.0059 0.0108
Trypanosoma brucei metacaspase 5, putative 0.0104 0.131 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0127 0.0513
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0092 0.1151 0.2071
Schistosoma mansoni amine GPCR 0.0018 0.016 0.016
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.2256 0.224
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.016 0.016
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0029 0.0306 0.4002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.016 0.0139
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.1151 0.1133
Onchocerca volvulus 0.0018 0.016 0.047
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0063 0.0764 0.0745
Brugia malayi Cytochrome P450 family protein 0.0022 0.0211 0.0535
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.015 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus granulosus caspase 8 0.0104 0.131 0.1292
Echinococcus granulosus tissue type plasminogen activator 0.0019 0.0167 0.0147
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0063 0.0823
Leishmania major cytochrome p450-like protein 0.0014 0.0098 0.0284
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0407 0.0387
Schistosoma mansoni coup transcription factor 0.0008 0.0021 0.0021
Trypanosoma brucei metacaspase MCA3 0.0104 0.131 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.0139 0.0634
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0013 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni sterol O-acyltransferase 1 0.0298 0.3904 0.3904
Leishmania major glycerol uptake protein, putative 0.0029 0.0306 0.1948
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0407 0.0387
Plasmodium falciparum glutathione reductase 0.0016 0.0127 0.0969
Brugia malayi ORL1-like opioid receptor 0.0018 0.016 0.0391
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0017 0.0139 0.0296
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Trypanosoma cruzi GUP1, putative 0.0029 0.0306 0.1948
Brugia malayi hypothetical protein 0.0274 0.3575 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0306 0.0523
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0127 0.0542
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.016 0.0139
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0127 0.0513
Onchocerca volvulus 0.0018 0.016 0.047
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0013 0.0088 0.0188
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0098 0.0284
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0013 0.0088 0.0668
Brugia malayi Dopamine receptor protein 1 0.0018 0.016 0.0391
Brugia malayi MBOAT family protein 0.0029 0.0306 0.0803
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Loa Loa (eye worm) MBOAT family protein 0.0029 0.0306 0.0523
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0315 0.0315
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0589 0.104
Onchocerca volvulus 0.0019 0.0167 0.0495
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0013 0.0088 0.0067
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.016 0.0139
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0315 0.2145
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.1111 0.1093
Toxoplasma gondii endonuclease IV APN 0.0074 0.0901 0.654
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0.0088 0.0286
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0127 0.0513
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Loa Loa (eye worm) hypothetical protein 0.0013 0.0088 0.0123
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0106 0.0086
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Loa Loa (eye worm) hypothetical protein 0.0031 0.0334 0.0574
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0127 0.073
Loa Loa (eye worm) hypothetical protein 0.0105 0.1322 0.2385
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0019 0.0175 0.0524
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0105 0.1322 0.1304
Onchocerca volvulus 0.0018 0.016 0.047
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0862 0.0844
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0436 0.1168
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0.0088 0.0198
Schistosoma mansoni alpha glucosidase 0.0039 0.0436 0.0436
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.016 0.0139
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.016 0.0255
Plasmodium falciparum plasmepsin IV 0.0011 0.0059 0.0451
Schistosoma mansoni cpg binding protein 0.0053 0.0624 0.0624
Brugia malayi glutathione reductase 0.0045 0.0524 0.1416
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.016 0.0255
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0011 0.0059 0.0059
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0436 0.1457
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.016 0.0139
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.016 0.0139
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0017 0.0139 0.0843
Loa Loa (eye worm) hhat protein 0.0029 0.0306 0.0523
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.011 0.0361
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0101 0.0147
Brugia malayi Hhat protein 0.0029 0.0306 0.0803
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Mycobacterium ulcerans hypothetical protein 0.0019 0.0175 0.096
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.016 0.0139
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.011 0.0361
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0127 0.0969
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0436 0.0416
Onchocerca volvulus 0.0018 0.016 0.047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.016 0.0139
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0013 0.0088 0.0286
Onchocerca volvulus 0.0101 0.127 0.4226
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0051 0.0056
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0013 0.0088 0.0067
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Plasmodium falciparum plasmepsin VI 0.0011 0.0059 0.0451
Brugia malayi Glycosyl hydrolases family 31 protein 0.0175 0.2256 0.6291
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0088 0.0435
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0029 0.0306 0.0286
Leishmania major hypothetical protein, conserved 0.0013 0.0088 0.0198
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.016 0.016
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0013 0.0088 0.0188
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Onchocerca volvulus 0.0018 0.016 0.047
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0255
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0056
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0011 0.0059 0.0071
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0063 0.0764 0.0764
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0113 0.1432 0.1432
Schistosoma mansoni neuropeptide receptor 0.0018 0.016 0.016
Schistosoma mansoni histamine h1 receptor 0.0018 0.016 0.016
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.011 0.0376
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0901 0.591
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0077 0.025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0106 0.0106
Brugia malayi aspartic protease BmAsp-2, identical 0.0011 0.0059 0.0108
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0127 0.0127
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0013 0.0088 0.0198
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.016 0.0255
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.016
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0118 0.0178
Treponema pallidum exodeoxyribonuclease (exoA) 0.0017 0.0139 0.0647
Echinococcus granulosus sex peptide receptor 0.0018 0.016 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.016 0.016
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0.0088 0.0286
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0013 0.0088 0.0088
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0013 0.0088 0.0198
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0051 0.0031
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0029 0.0306 0.0286
Plasmodium falciparum thioredoxin reductase 0.0045 0.0524 0.3998
Schistosoma mansoni hypothetical protein 0.0321 0.4205 0.4205
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.016 0.0139
Brugia malayi Protein kinase domain containing protein 0.0014 0.0101 0.0227
Onchocerca volvulus 0.0053 0.0624 0.2043
Brugia malayi hypothetical protein 0.0244 0.3178 0.8884
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0105 0.1322 1
Brugia malayi hypothetical protein 0.0018 0.016 0.0391
Schistosoma mansoni cpg binding protein 0.0056 0.0665 0.0665
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0051 0.0031
Loa Loa (eye worm) hypothetical protein 0.0059 0.0712 0.1266
Loa Loa (eye worm) hypothetical protein 0.0074 0.0901 0.1613
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0901 0.6728
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.016 0.0139
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.016 0.0139

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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