Detailed information for compound 1204454

Basic information

Technical information
  • TDR Targets ID: 1204454
  • Name: ethyl 3-[4-(2,5-dimethylphenyl)piperazin-1-yl ]sulfonyl-1-benzothiophene-2-carboxylate
  • MW: 458.594 | Formula: C23H26N2O4S2
  • H donors: 0 H acceptors: 3 LogP: 4.96 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1sc2c(c1S(=O)(=O)N1CCN(CC1)c1cc(C)ccc1C)cccc2
  • InChi: 1S/C23H26N2O4S2/c1-4-29-23(26)21-22(18-7-5-6-8-20(18)30-21)31(27,28)25-13-11-24(12-14-25)19-15-16(2)9-10-17(19)3/h5-10,15H,4,11-14H2,1-3H3
  • InChiKey: RKTLUBPSBWAAKJ-UHFFFAOYSA-N  


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Synonyms

  • ethyl 3-[4-(2,5-dimethylphenyl)piperazin-1-yl]sulfonylbenzothiophene-2-carboxylate
  • 3-[[4-(2,5-dimethylphenyl)-1-piperazinyl]sulfonyl]-2-benzothiophenecarboxylic acid ethyl ester
  • 3-[4-(2,5-dimethylphenyl)piperazin-1-yl]sulfonylbenzothiophene-2-carboxylic acid ethyl ester
  • G226-0159
  • NCGC00129519-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.1254 0.1254
Leishmania major cathepsin L-like protease 0.002 0.0026 0.0292
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0147 0.0147
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0051 0.0245
Echinococcus multilocularis musashi 0.0033 0.0076 0.0076
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0116 0.0566
Loa Loa (eye worm) hypothetical protein 0.0048 0.0139 0.0139
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0073 0.024 0.024
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0014 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0116 0.0418 0.4866
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0116 0.0418 0.2058
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0026 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.005 0.005
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Brugia malayi hypothetical protein 0.004 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0716 0.3528
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0213 0.081 0.081
Brugia malayi intermediate filament protein 0.0033 0.0076 0.0076
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0332 0.1294 0.1294
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0037 0.0037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.011 0.1274
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0036 0.041
Loa Loa (eye worm) hypothetical protein 0.0032 0.0074 0.0074
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0099 0.1205
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0213 0.081 0.081
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.005 0.005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0147 0.1707
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.0418 0.0418
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0099 0.0099
Toxoplasma gondii exonuclease III APE 0.0038 0.0099 0.1102
Mycobacterium leprae conserved hypothetical protein 0.0116 0.0418 0.2058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0054 0.0261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Leishmania major hypothetical protein, conserved 0.0027 0.0055 0.0625
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0511 0.2026 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.0418 0.2055
Brugia malayi hypothetical protein 0.0018 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.002 0.0026 0.0305
Onchocerca volvulus 0.002 0.0026 0.0247
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Trypanosoma brucei unspecified product 0.0016 0.0007 0.0075
Echinococcus multilocularis lamin dm0 0.0033 0.0076 0.0076
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.247 1 1
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0055 0.0603
Brugia malayi Cytochrome P450 family protein 0.0023 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.086 0.3446 0.3446
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0099 0.0929
Loa Loa (eye worm) hypothetical protein 0.0209 0.0794 0.0794
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0125 0.0452 0.2223
Echinococcus granulosus neuropeptide receptor A26 0.0917 0.3678 0.3678
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.005 0.005
Brugia malayi MBOAT family protein 0.0213 0.081 0.081
Schistosoma mansoni polycystin 1-related 0.004 0.0108 0.0108
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0073 0.024 0.2689
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0035 0.0085 0.0085
Schistosoma mansoni ap endonuclease 0.0038 0.0099 0.0099
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Schistosoma mansoni cytochrome P450 0.0014 0.0001 0.0001
Onchocerca volvulus 0.004 0.0108 0.1076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0054 0.0261
Loa Loa (eye worm) hypothetical protein 0.005 0.0147 0.0147
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0037 0.0175
Toxoplasma gondii histone lysine methyltransferase SET1 0.0232 0.0889 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0035 0.0085 0.0085
Leishmania major glycerol uptake protein, putative 0.0213 0.081 0.945
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0035 0.0085 0.0412
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0116 0.0418 0.0418
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0035 0.0085 0.0085
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0026 0.0026
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.005 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0026 0.0292
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.01 0.01
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.005 0.0492
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0026
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0099 0.1142
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0019 0.0019
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0332 0.1294 0.1294
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0511 0.2026 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0099 0.0099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0213 0.081 0.9115
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.005 0.005
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0116 0.0418 0.0418
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0099 0.0099
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0002 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0036 0.041
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0418 0.2055
Loa Loa (eye worm) histone methyltransferase 0.0038 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0085 0.0085
Trypanosoma cruzi GUP1, putative 0.0213 0.081 0.945
Onchocerca volvulus 0.012 0.0432 0.4363
Echinococcus multilocularis survival motor neuron protein 1 0.0266 0.1025 0.1025
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0389 0.0389
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0244 0.1199
Echinococcus multilocularis lamin 0.0033 0.0076 0.0076
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.005 0.005
Leishmania major hypothetical protein, conserved 0.0035 0.0085 0.0982
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0014 0.0002 0.0002
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0035 0.0085 0.0982
Brugia malayi CXXC zinc finger family protein 0.012 0.0432 0.0432
Brugia malayi beta-lactamase family protein 0.0116 0.0418 0.0418
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.005 0.005
Trypanosoma brucei glycerol uptake protein, putative 0.0213 0.081 0.945
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0125 0.0452 0.2223
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.023 0.2675
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0244 0.2842
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0034 0.0385
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Echinococcus granulosus microtubule associated protein 2 0.0692 0.2761 0.2761
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Schistosoma mansoni hypothetical protein 0.0109 0.0389 0.0389
Schistosoma mansoni GTP-binding protein alpha subunit 0.0014 0.0002 0.0002
Echinococcus granulosus cathepsin l1 0.002 0.0026 0.0026
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0213 0.081 0.081
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0224 0.0857 1
Echinococcus granulosus survival motor neuron protein 1 0.0266 0.1025 0.1025
Plasmodium vivax ornithine aminotransferase, putative 0.0073 0.024 0.2725
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.005 0.005
Echinococcus granulosus snurportin 1 0.0322 0.1254 0.1254
Echinococcus granulosus neuropeptide s receptor 0.0917 0.3678 0.3678
Plasmodium vivax hypothetical protein, conserved 0.0116 0.0418 0.4995
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.01 0.01
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Onchocerca volvulus Cathepsin L homolog 0.002 0.0026 0.0247
Trichomonas vaginalis set domain proteins, putative 0.0257 0.0989 0.4877
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0244 0.2842
Plasmodium falciparum GAF domain-related protein, putative 0.009 0.031 0.3818
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0073 0.024 0.0803
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0418 0.4866
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0745 0.2976 0.2976
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0244 0.0244
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0134 0.0491 0.2417
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.005 0.005
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0108 0.0108
Echinococcus multilocularis neuropeptide receptor A26 0.0917 0.3678 0.3678
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0147 0.0147
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0982
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0412
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0036 0.041
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0073 0.024 0.024
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0147 0.0147
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0037 0.0095 0.1099
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Entamoeba histolytica hypothetical protein 0.0109 0.0389 0.4795
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0002 0.0002
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0244 0.0244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.005 0.005
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.0244 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1009 0.4975
Loa Loa (eye worm) hypothetical protein 0.0213 0.081 0.081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.005 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0257 0.2993
Loa Loa (eye worm) hypothetical protein 0.004 0.0108 0.0108
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.0418 0.0418
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0531 0.0531
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.007 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.005 0.005
Echinococcus granulosus beta LACTamase domain containing family member 0.0116 0.0418 0.0418
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0035 0.0085 0.1035
Echinococcus multilocularis cysteine protease 0.002 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0188 0.0924
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0213 0.081 1
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0036 0.0173
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0188 0.0188
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Loa Loa (eye worm) hypothetical protein 0.0093 0.0324 0.0324
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0014 0.0002 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0102 0.3229
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0095 0.0317
Toxoplasma gondii hypothetical protein 0.009 0.031 0.3482
Schistosoma mansoni GTP-binding protein alpha subunit 0.0014 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.005 0.005
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.0002 0.0002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.011 0.0536
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0008 0.0008
Loa Loa (eye worm) fibroinase 0.002 0.0026 0.0026
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.011 0.1274
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0085 0.0085
Toxoplasma gondii ABC1 family protein 0.0116 0.0418 0.4693
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.005 0.005
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0073 0.024 0.1179
Loa Loa (eye worm) PDE1B protein 0.0035 0.0085 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0418 0.4866
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0014 0.0002 0.0002
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0116 0.1152
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.0002 0.0002
Mycobacterium leprae Probable lipase LipE 0.0116 0.0418 0.2058
Brugia malayi nuclear hormone receptor 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0014 0.0002 0.0002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0034 0.0385
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0716 0.3528
Entamoeba histolytica hypothetical protein 0.0109 0.0389 0.4795
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.005 0.005
Echinococcus multilocularis importin subunit beta 1 0.003 0.0066 0.0066
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Mycobacterium tuberculosis Probable aminotransferase 0.0511 0.2026 0.6816
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.005 0.005
Brugia malayi Inositol-1 0.0041 0.011 0.011
Brugia malayi beta-lactamase 0.0116 0.0418 0.0418
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0224 0.0857 0.0857
Brugia malayi MAP kinase sur-1 0.005 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Plasmodium vivax hypothetical protein, conserved 0.009 0.031 0.3624
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0418 0.2055
Entamoeba histolytica hypothetical protein, conserved 0.0213 0.081 1
Leishmania major cAMP-specific phosphodiesterase, putative 0.0035 0.0085 0.0982
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0244 0.2842
Schistosoma mansoni hypothetical protein 0.0054 0.0164 0.0164
Trichomonas vaginalis esterase, putative 0.0116 0.0418 0.2055
Echinococcus granulosus GPCR family 2 0.0016 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0026 0.005 0.005
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0014 0.0002 0.0002
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0175 0.0658 0.0658
Loa Loa (eye worm) hypothetical protein 0.0074 0.0244 0.0244
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0066 0.0737
Schistosoma mansoni inositol monophosphatase 0.0041 0.011 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0331 0.1293 0.1293
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0026 0.0305
Leishmania major cathepsin L-like protease 0.002 0.0026 0.0292
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0035 0.0085 0.0085
Mycobacterium ulcerans hypothetical protein 0.0511 0.2026 1
Leishmania major hypothetical protein, conserved 0.0035 0.0085 0.0982
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0073 0.024 0.1179
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0035 0.0085 0.0982
Brugia malayi Importin beta-1 subunit 0.003 0.0066 0.0066
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.011 0.0536
Leishmania major cysteine peptidase A (CPA) 0.002 0.0026 0.0292
Giardia lamblia DINP protein human, muc B family 0.0023 0.0036 0.01
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0188 0.0188
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0073 0.024 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0035 0.0085 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0051 0.058
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0188 0.0924
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0014 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0147 0.1707
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0026 0.0305
Giardia lamblia Hypothetical protein 0.0035 0.0085 0.2428
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0188 0.2109
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0093 0.0309
Schistosoma mansoni thyroid hormone receptor 0.0026 0.005 0.005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0026 0.0026
Echinococcus multilocularis microtubule associated protein 2 0.0692 0.2761 0.2761
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0083 0.0083
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0035 0.0085 0.0085
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.005 0.005
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0051 0.058
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Leishmania major glycerol uptake protein, putative 0.0213 0.081 0.945
Onchocerca volvulus 0.002 0.0026 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0035 0.0085 0.0085
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0099 0.2549
Entamoeba histolytica Ran family GTPase 0.0022 0.0034 0.0404
Schistosoma mansoni myst-related protein 0.0014 0.0001 0.0001
Echinococcus multilocularis neuropeptide s receptor 0.0917 0.3678 0.3678
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0139 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0147 0.0147
Leishmania major glycerol uptake protein, putative 0.0213 0.081 0.945
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0073 0.024 0.1179
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0026
Brugia malayi Pre-SET motif family protein 0.0035 0.0085 0.0085
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0014 0.0002 0.0002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0099 0.1142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Trypanosoma cruzi glycerol uptake protein, putative 0.0213 0.081 0.945
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0015 0.0015
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Onchocerca volvulus 0.002 0.0026 0.0247
Schistosoma mansoni lipoxygenase 0.0103 0.0362 0.0362
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0076 0.0076
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0034 0.0034
Echinococcus granulosus zinc finger protein 0.2257 0.9133 0.9133
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0224 0.0857 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0054 0.0261
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0073 0.024 0.0803
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0055 0.0625
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.005 0.0492
Toxoplasma gondii hypothetical protein 0.009 0.031 0.3482
Echinococcus granulosus RUN 0.004 0.0108 0.0108
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.005 0.005
Echinococcus granulosus o acyltransferase membrane bound domain 0.0213 0.081 0.081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0331 0.1293 0.1293
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0085 0.0085
Schistosoma mansoni zinc finger protein 0.247 1 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.005 0.0492
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0389 0.0389
Loa Loa (eye worm) doublecortin family protein 0.004 0.0108 0.0108
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0008 0.0008
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0036 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0213 0.081 0.081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.005 0.005
Schistosoma mansoni hypothetical protein 0.004 0.0108 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0054 0.0261
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0026 0.0305
Mycobacterium ulcerans lipase LipD 0.0116 0.0418 0.2058
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0007 0.0075
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0134 0.0491 0.2417
Echinococcus granulosus importin subunit beta 1 0.003 0.0066 0.0066
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.1035
Loa Loa (eye worm) cytochrome P450 0.0014 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0099 0.1142
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0051 0.0559
Brugia malayi Hhat protein 0.0213 0.081 0.081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Echinococcus multilocularis dna polymerase eta 0.0023 0.0036 0.0036
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0099 0.0635
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0108 0.0108
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0035 0.0085 0.0085
Entamoeba histolytica hypothetical protein 0.0026 0.0051 0.0609
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0531 0.0531
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0002 0.0002
Trypanosoma brucei unspecified product 0.0023 0.0036 0.041
Echinococcus multilocularis expressed protein 0.0014 0.0002 0.0002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0043 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0002 0.0002
Echinococcus granulosus lamin dm0 0.0033 0.0076 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0418 0.4866
Schistosoma mansoni hypothetical protein 0.0322 0.1254 0.1254
Brugia malayi RNA, U transporter 1 0.0086 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0116 0.0418 0.0418
Schistosoma mansoni inositol monophosphatase 0.0041 0.011 0.011
Leishmania major cathepsin L-like protease 0.002 0.0026 0.0292
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0102 0.1244
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0014 0.0002 0.0002
Echinococcus granulosus muscleblind protein 0.1418 0.5716 0.5716
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0036 0.0118
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0331 0.1293 0.1293
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0716 0.3528
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0116 0.0418 0.1402
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.0066
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0147 0.0147
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.0244 0.0244
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0982
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0418 0.2055
Mycobacterium ulcerans esterase/lipase LipP 0.0116 0.0418 0.2058
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0085 0.0085
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0037 0.0037
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.005 0.005
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0213 0.081 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.009 0.031 0.1524
Loa Loa (eye worm) MBOAT family protein 0.247 1 1
Leishmania major GTP-binding protein, putative 0.0022 0.0034 0.0385
Leishmania major cathepsin L-like protease 0.0077 0.0257 0.2993
Echinococcus granulosus L aminoadipate semialdehyde 0.0093 0.0324 0.0324
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0213 0.081 0.081
Trypanosoma brucei unspecified product 0.0016 0.0007 0.0075
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0531 0.0531
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0412
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0108 0.0108
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0099 0.048
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0051 0.0609
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0034 0.0034
Loa Loa (eye worm) MBOAT family protein 0.0213 0.081 0.081
Echinococcus multilocularis dnaJ subfamily B 0.086 0.3446 0.3446
Onchocerca volvulus 0.004 0.0108 0.1076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0331 0.1293 0.1293
Brugia malayi Cytochrome P450 family protein 0.0014 0.0001 0.0001
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.011 0.1274
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0037 0.0095 0.1099
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.011 0.011
Brugia malayi Muscleblind-like protein 0.1418 0.5716 0.5716
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0051 0.0167
Leishmania major glycerol uptake protein, putative 0.0213 0.081 0.945
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.007 0.007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0035 0.0085 0.0085
Schistosoma mansoni survival motor neuron protein 0.0054 0.0164 0.0164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0982
Brugia malayi MH2 domain containing protein 0.013 0.0471 0.0471
Loa Loa (eye worm) hypothetical protein 0.0266 0.1025 0.1025
Brugia malayi MBOAT family protein 0.0213 0.081 0.081
Onchocerca volvulus 0.0213 0.081 0.819
Schistosoma mansoni cpg binding protein 0.0127 0.046 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.081 0.3994
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0007 0.0075
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Schistosoma mansoni lipoxygenase 0.0175 0.0658 0.0658
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0085 0.0412
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Mycobacterium leprae conserved hypothetical protein 0.009 0.031 0.1527
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0147 0.0719
Loa Loa (eye worm) ctsf protein 0.002 0.0026 0.0026
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0085 0.0412
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.005 0.005
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0085 0.0085
Plasmodium falciparum importin beta, putative 0.003 0.0066 0.0804
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0331 0.1293 0.1293
Echinococcus multilocularis RUN 0.004 0.0108 0.0108
Onchocerca volvulus 0.0035 0.0085 0.0842
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0244 0.0244
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0754
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0036 0.0118
Onchocerca volvulus 0.0116 0.0418 0.4214
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0036 0.041
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0036 0.0036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0069 0.0069
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0093 0.0324 0.0324
Brugia malayi Cytochrome P450 family protein 0.0023 0.0037 0.0037
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0026
Schistosoma mansoni cpg binding protein 0.012 0.0432 0.0432
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.005 0.005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0099 0.0483
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0026 0.0305
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0037 0.0414
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.005 0.005
Echinococcus granulosus dna polymerase eta 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0033 0.0076 0.0756
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.005 0.005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0085 0.0412
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.019 0.2209
Onchocerca volvulus 0.0026 0.005 0.0492
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0035 0.0085 0.0085
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0014 0.0002 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.011 0.0539
Trypanosoma brucei protein kinase, putative 0.005 0.0147 0.1707
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0035 0.0085 0.0412
Plasmodium falciparum phosphodiesterase delta, putative 0.0035 0.0085 0.1035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0036 0.041
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0051 0.0245
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Loa Loa (eye worm) hhat protein 0.0213 0.081 0.081
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0035 0.0085 0.0085
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0108 0.0108
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0043 0.0493
Trichomonas vaginalis porcupine, putative 0.0213 0.081 0.3994
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.005 0.005
Echinococcus granulosus intermediate filament protein 0.0033 0.0076 0.0076
Mycobacterium tuberculosis Conserved protein 0.0116 0.0418 0.1402
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0102 0.1244
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0257 0.2993
Trypanosoma cruzi GUP1, putative 0.0213 0.081 0.945
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0066 0.0764
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0244 0.1199
Schistosoma mansoni thyroid hormone receptor 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0213 0.081 1
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0026 0.0026
Plasmodium vivax SET domain protein, putative 0.0035 0.0085 0.0749
Leishmania major cathepsin L-like protease 0.002 0.0026 0.0292
Loa Loa (eye worm) hypothetical protein 0.0297 0.1153 0.1153
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0035 0.0085 0.0085
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0035 0.0085 0.0085
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0147 0.1707
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0036 0.0036
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0036 0.0036
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.009 0.031 0.1041
Schistosoma mansoni DNA polymerase eta 0.0023 0.0036 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0085 0.0982
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0036 0.0036
Echinococcus multilocularis GPCR, family 2 0.0016 0.0008 0.0008
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0116 0.1299
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0116 0.0418 0.0418
Loa Loa (eye worm) G protein alpha subunit 3 0.0014 0.0002 0.0002
Echinococcus granulosus expressed protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0055 0.0625
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0001
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.011 0.0536
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.005 0.005
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0982
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0116 0.0418 0.1402
Loa Loa (eye worm) CXXC zinc finger family protein 0.012 0.0432 0.0432
Echinococcus multilocularis Aminotransferase class III 0.0073 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Onchocerca volvulus Cathepsin L homolog 0.002 0.0026 0.0247
Schistosoma mansoni cpg binding protein 0.0127 0.046 0.046
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.005 0.005
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0093 0.0324 0.0324
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0036 0.017
Mycobacterium ulcerans putative regulatory protein 0.009 0.031 0.1527
Leishmania major cathepsin L-like protease 0.0077 0.0257 0.2993
Onchocerca volvulus 0.002 0.0026 0.0247
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0035 0.0085 0.0085
Toxoplasma gondii GAF domain-containing protein 0.009 0.031 0.3482
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0116 0.0418 0.2058
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0034 0.0404
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0035 0.0085 0.0982
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.011 0.1345
Echinococcus multilocularis tumor protein p63 0.0327 0.1276 0.1276
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0008 0.0008
Echinococcus multilocularis ornithine aminotransferase 0.0073 0.024 0.024
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0026 0.0026
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0015 0.0015
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0108 0.0108
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0055 0.0658
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0085 0.0085
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.0244 1
Mycobacterium ulcerans acetylornithine aminotransferase 0.0073 0.024 0.1179
Brugia malayi hypothetical protein 0.0027 0.0055 0.0055
Brugia malayi hypothetical protein 0.0109 0.0389 0.0389
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0754
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0026 0.012
Loa Loa (eye worm) hypothetical protein 0.0207 0.0787 0.0787
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0244 0.0244
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0116 0.0418 0.0418
Plasmodium falciparum ornithine aminotransferase 0.0073 0.024 0.2947
Echinococcus multilocularis muscleblind protein 1 0.1418 0.5716 0.5716
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0175 0.0658 0.0658
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0109 0.0389 0.4795
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0224 0.0857 0.0857
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.005 0.005
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0224 0.0857 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0982
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0213 0.081 0.081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Entamoeba histolytica G protein alpha subunit, putative 0.0014 0.0002 0.0004
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0224 0.0857 0.4227
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.005 0.005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0051 0.0314
Loa Loa (eye worm) hypothetical protein 0.004 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.011 0.3147
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.081 0.3994
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0099 0.1205
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0331 0.1293 0.1293
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0213 0.081 0.081
Schistosoma mansoni lamin 0.0033 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0213 0.081 0.081
Schistosoma mansoni loxhd1 0.004 0.0108 0.0108
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.005 0.005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0099 0.0329
Plasmodium falciparum phosphodiesterase gamma, putative 0.0035 0.0085 0.1035
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0051 0.0245
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.005 0.005
Mycobacterium ulcerans putative regulatory protein 0.009 0.031 0.1527
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0034 0.0034
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0008 0.0008
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0055 0.0625
Treponema pallidum alginate O-acetylation protein (algI) 0.0213 0.081 1
Plasmodium vivax phosphodiesterase gamma, putative 0.0035 0.0085 0.0754
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0147 0.1707
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1685 0.6805 0.6805
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0008 0.0008
Echinococcus multilocularis 0.0014 0.0001 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0076 0.0076
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.011 0.1229
Onchocerca volvulus 0.002 0.0026 0.0247
Mycobacterium ulcerans beta-lactamase 0.0116 0.0418 0.2058
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0035 0.0085 0.0982
Brugia malayi beta-lactamase family protein 0.0116 0.0418 0.0418
Schistosoma mansoni myst-related protein 0.0014 0.0001 0.0001
Brugia malayi nuclear receptor NHR-88 0.0026 0.005 0.005
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.247 1 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0036 0.041
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0213 0.081 0.081
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0036 0.017
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.0244 0.3005
Entamoeba histolytica vacuolar protein sorting 26 0.0213 0.081 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0412
Mycobacterium tuberculosis Conserved protein 0.0116 0.0418 0.1402
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0037 0.0414
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0213 0.081 0.081
Schistosoma mansoni rab6-interacting 0.004 0.0108 0.0108
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0026 0.012
Mycobacterium tuberculosis Probable hydrolase 0.0116 0.0418 0.1402
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0116 0.0566
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0073 0.024 0.0803
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0147 0.0719
Brugia malayi Cytochrome P450 family protein 0.0052 0.0156 0.0156
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0054 0.0261
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0099 0.048
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0073 0.024 0.1179
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0224 0.0857 0.4227
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.005 0.005
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0147 0.1707
Loa Loa (eye worm) beta-lactamase 0.0116 0.0418 0.0418
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0026
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0116 0.0116
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0213 0.081 0.081
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0244 0.2842
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0108 0.0108
Onchocerca volvulus 0.0033 0.0076 0.0756
Echinococcus multilocularis sterol O acyltransferase 1 0.0213 0.081 0.081
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0213 0.081 0.081
Trichomonas vaginalis hypothetical protein 0.0015 0.0003 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0073 0.024 0.0803
Brugia malayi Pre-SET motif family protein 0.0226 0.0863 0.0863
Loa Loa (eye worm) hypothetical protein 0.1418 0.5716 0.5716
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0085 0.0085
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Loa Loa (eye worm) hypothetical protein 0.0116 0.0418 0.0418
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0213 0.081 0.081
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0035 0.0085 0.0085
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0116 0.1299
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0108 0.1044
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0213 0.081 0.081
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0099 0.1142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0054 0.0261
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0471 0.0471
Leishmania major cytochrome p450-like protein 0.0023 0.0037 0.0414
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0026
Echinococcus multilocularis zinc finger protein 0.2257 0.9133 0.9133
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0188 0.063
Echinococcus granulosus dna polymerase kappa 0.0023 0.0036 0.0036
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0188 0.0188
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0224 0.0857 0.4227
Loa Loa (eye worm) acetyltransferase 0.0144 0.0531 0.0531
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0026 0.0026
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.005 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.005 0.005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0054 0.0261
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0331 0.1293 0.1293
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0213 0.081 0.081
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0073 0.024 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.0863 0.0863
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0331 0.1293 0.1293
Loa Loa (eye worm) hypothetical protein 0.0116 0.0418 0.0418
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0471 0.0471
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0237 0.116
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0066 0.0764
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0147 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.0244 0.0244
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Echinococcus granulosus o acyltransferase membrane bound domain 0.0213 0.081 0.081
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0073 0.024 0.1179
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0035 0.0085 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0209 0.0794 0.0794
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0026
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0037 0.0414
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0043 0.0205
Mycobacterium tuberculosis Probable lipase LipE 0.0116 0.0418 0.1402
Brugia malayi MBOAT family protein 0.0213 0.081 0.081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0034 0.0385
Brugia malayi follicle stimulating hormone receptor 0.0745 0.2976 0.2976
Leishmania major glycerol uptake protein, putative 0.0213 0.081 0.945
Onchocerca volvulus 0.002 0.0026 0.0247
Echinococcus granulosus lamin 0.0033 0.0076 0.0076
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0213 0.081 0.9115
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0073 0.024 0.1179
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Brugia malayi hypothetical protein 0.004 0.0108 0.0108
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0147 0.5381
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0389 0.0389
Loa Loa (eye worm) hypothetical protein 0.0213 0.081 0.081
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0188 0.0188
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0213 0.081 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.005 0.005
Toxoplasma gondii hypothetical protein 0.0213 0.081 0.9115
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0035 0.0085 0.0085
Echinococcus granulosus tumor protein p63 0.0327 0.1276 0.1276
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0244 0.1199
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.0418 0.2055
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.005 0.005
Trypanosoma cruzi glycerol uptake protein, putative 0.0213 0.081 0.945
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0026 0.0026
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0099 0.0099
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0055 0.0364
Echinococcus granulosus dnaJ subfamily B 0.086 0.3446 0.3446
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0116 0.0418 0.1402
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.005 0.005
Echinococcus multilocularis ornithine aminotransferase 0.0073 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0008
Schistosoma mansoni microtubule-associated protein tau 0.0692 0.2761 0.2761
Leishmania major DNA polymerase eta, putative 0.0023 0.0036 0.041
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0134 0.0491 0.572
Brugia malayi MBOAT family protein 0.0213 0.081 0.081
Loa Loa (eye worm) hhat protein 0.0213 0.081 0.081
Echinococcus multilocularis muscleblind protein 0.1418 0.5716 0.5716
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0036 0.0036
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.011 0.1274
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0511 0.2026 0.6816
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0036 0.041
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0224 0.0857 0.0857
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0034 0.0083 0.0083
Echinococcus multilocularis beta LACTamase domain containing family member 0.0116 0.0418 0.0418
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0188 0.2186
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0035 0.0085 0.0085
Onchocerca volvulus 0.002 0.0026 0.0247
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0007 0.0075
Brugia malayi diacylglycerol acyltransferase 0.0213 0.081 0.081
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0109 0.0389 0.4795
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0244 0.0244
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0156 0.0156
Trichomonas vaginalis ran, putative 0.0022 0.0034 0.016
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0014 0.0002 0.0002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0262 0.1009 0.4975
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0035 0.0085 0.2428
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0055 0.0658
Mycobacterium tuberculosis Conserved protein 0.0116 0.0418 0.1402
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0014 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.0077 0.0257 0.2993
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0224 0.0857 0.4227
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0213 0.081 0.081
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0035 0.0085 0.0085
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0213 0.081 0.081
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0035 0.0085 0.0982
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0147 0.1707
Schistosoma mansoni ran 0.0022 0.0034 0.0034
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0127 0.0462 0.2274
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0073 0.024 0.1179
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0224 0.0857 1
Echinococcus multilocularis snurportin 1 0.0322 0.1254 0.1254
Loa Loa (eye worm) hypothetical protein 0.0116 0.0418 0.0418
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0224 0.0857 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0034 0.0034
Onchocerca volvulus 0.0116 0.0418 0.4214
Loa Loa (eye worm) inositol-1 0.0041 0.011 0.011
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0034 0.0372
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.007 0.007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Plasmodium vivax importin-beta 2, putative 0.003 0.0066 0.0515
Leishmania major DNA polymerase kappa, putative 0.0023 0.0036 0.041
Toxoplasma gondii cathepsin CPL 0.002 0.0026 0.0281
Trypanosoma cruzi glycerol uptake protein, putative 0.0213 0.081 0.945
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.005 0.005
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0213 0.081 0.081
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0026 0.0305
Echinococcus granulosus FTZ F1 alpha 0.0026 0.005 0.005
Brugia malayi steroid hormone receptor 0.0026 0.005 0.005
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.007 0.007
Mycobacterium ulcerans L-lysine aminotransferase 0.0073 0.024 0.1179
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.005 0.005
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0035 0.0085 0.0085
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0026 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0256 0.0985 0.0985
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0332 0.1294 0.1294
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0213 0.081 0.081
Brugia malayi Doublecortin family protein 0.004 0.0108 0.0108
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0213 0.081 0.081
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0188 0.0924
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0035 0.0085 0.0982
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0001 0.0001
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.1035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0026 0.0026
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0076 0.0076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0054 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.005 0.005
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0412
Schistosoma mansoni ran 0.0022 0.0034 0.0034
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.007 0.007
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Brugia malayi G-protein alpha subunit 0.0014 0.0002 0.0002
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0014 0.0002 0.0002
Trichomonas vaginalis transmembrane protein nessy, putative 0.0213 0.081 0.3994
Schistosoma mansoni sterol O-acyltransferase 1 0.0213 0.081 0.081
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0213 0.081 0.081
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0037 0.0095 0.1099
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0085 0.0754
Onchocerca volvulus 0.0257 0.0989 1
Echinococcus granulosus sterol O acyltransferase 1 0.0213 0.081 0.081
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0982
Loa Loa (eye worm) hypothetical protein 0.1418 0.5716 0.5716
Toxoplasma gondii hypothetical protein 0.019 0.0716 0.8053
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0035 0.0085 0.0982
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.005 0.005
Entamoeba histolytica hypothetical protein 0.0213 0.081 1
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0511 0.2026 1
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0014 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.002 0.0026 0.0292
Onchocerca volvulus 0.0093 0.0324 0.3265
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0026 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0003 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0036 0.041
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0085 0.0943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0331 0.1293 0.1293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Loa Loa (eye worm) cysteine protease 0.002 0.0026 0.0026
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0014 0.0002 0.0002
Loa Loa (eye worm) MBOAT family protein 0.0213 0.081 0.081
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0036 0.041
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0147 0.0719
Entamoeba histolytica hypothetical protein 0.0024 0.0043 0.0518
Echinococcus granulosus cpg binding protein 0.0127 0.046 0.046
Schistosoma mansoni coup transcription factor 0.0026 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0147 0.0147
Schistosoma mansoni lamin 0.0033 0.0076 0.0076
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0257 0.2993
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0026 0.012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0237 0.116
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0213 0.081 0.945
Brugia malayi hypothetical protein 0.0266 0.1025 0.1025
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0982
Schistosoma mansoni intermediate filament proteins 0.0033 0.0076 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0003 0.0007
Trypanosoma brucei glycerol uptake protein, putative 0.0213 0.081 0.945
Schistosoma mansoni ap endonuclease 0.0038 0.0099 0.0099
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0147 0.1647
Schistosoma mansoni rab6-interacting 0.004 0.0108 0.0108
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.0002 0.0002
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0262 0.1009 0.4975
Echinococcus granulosus Aminotransferase class III 0.0073 0.024 0.024
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0262 0.1009 0.4975
Echinococcus granulosus o acyltransferase membrane bound domain 0.0213 0.081 0.081
Onchocerca volvulus 0.0048 0.0139 0.1388
Onchocerca volvulus 0.0116 0.0418 0.4214
Trichomonas vaginalis helicase, putative 0.0027 0.0054 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0036 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.081 0.3994
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0036 0.043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Onchocerca volvulus Cathepsin F homolog 0.002 0.0026 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Leishmania major importin beta-1 subunit, putative 0.0024 0.0043 0.0493
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0043 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.005 0.005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0125 0.0452 0.2223
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0014 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0085 0.0412
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Leishmania major hypothetical protein, conserved 0.0037 0.0095 0.1099
Echinococcus multilocularis L aminoadipate semialdehyde 0.0093 0.0324 0.0324
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0213 0.081 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0099 0.3082
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0514 0.0514
Brugia malayi cytochrome P450 0.0014 0.0001 0.0001
Echinococcus multilocularis cysteine protease 0.002 0.0026 0.0026
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0127 0.0462 0.155
Echinococcus multilocularis cpg binding protein 0.0127 0.046 0.046
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0035 0.0085 0.1035
Onchocerca volvulus 0.0054 0.0164 0.1648
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0008 0.0008
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0147 0.1707
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0036 0.0036
Giardia lamblia hypothetical protein 0.0035 0.0085 0.2428
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0051 0.0559
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0034 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0054 0.0261
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0036 0.0036
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0093 0.0453
Brugia malayi ecdysteroid receptor 0.0026 0.005 0.005
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.0244 0.0244
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0744 0.2972 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0085 0.0947
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0036 0.041
Schistosoma mansoni importin beta-1 0.003 0.0066 0.0066
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0083 0.0083
Mycobacterium tuberculosis Probable lipase LipD 0.0116 0.0418 0.1402
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0213 0.081 0.081
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0108 0.1317
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0036
Mycobacterium tuberculosis Probable esterase LipL 0.0116 0.0418 0.1402
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0014 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0257 0.2993
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0209 0.0794 0.0794
Echinococcus granulosus ornithine aminotransferase 0.0073 0.024 0.024
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0257 0.2993
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0026 0.0026
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0098 0.0098

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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