Detailed information for compound 1382905

Basic information

Technical information
  • TDR Targets ID: 1382905
  • Name: N-(5-methyl-1,2-oxazol-3-yl)-2-quinazolin-4-y lsulfanylacetamide
  • MW: 300.336 | Formula: C14H12N4O2S
  • H donors: 1 H acceptors: 4 LogP: 2.47 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1noc(c1)C)CSc1ncnc2c1cccc2
  • InChi: 1S/C14H12N4O2S/c1-9-6-12(18-20-9)17-13(19)7-21-14-10-4-2-3-5-11(10)15-8-16-14/h2-6,8H,7H2,1H3,(H,17,18,19)
  • InChiKey: KDDOCAGTMUZHJD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(5-methylisoxazol-3-yl)-2-quinazolin-4-ylsulfanyl-acetamide
  • N-(5-methyl-3-isoxazolyl)-2-(4-quinazolinylthio)acetamide
  • N-(5-methylisoxazol-3-yl)-2-(quinazolin-4-ylthio)acetamide
  • N-(5-methyl-1,2-oxazol-3-yl)-2-quinazolin-4-ylsulfanyl-ethanamide
  • MLS000118949
  • ZINC03490645
  • SMR000095888

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens pyruvate kinase, muscle Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Chlamydia trachomatis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pyruvate kinase, M2 isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium parvum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium yoelii pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Giardia lamblia Pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pyruvate kinase, muscle isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium berghei pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1 Get druggable targets OG5_126685 All targets in OG5_126685
Babesia bovis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Toxoplasma gondii pyruvate kinase PyK1 Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania donovani pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium knowlesi pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Pyruvate kinase isozyme R, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Theileria parva pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) pyruvate kinase-PB Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania mexicana pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium hominis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K00873 pyruvate kinase [EC2.7.1.40], putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum Pyruvate kinase (EC 2.7.1.40), related Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma congolense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium vivax pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Echinococcus granulosus pyruvate kinase pyruvate kinase, muscle 605 aa 521 aa 34.9 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus activated cdc42 kinase 1 0.0831 0.2105 0.4425
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0802 0.2023 0.2023
Onchocerca volvulus 0.0707 0.1756 0.1768
Schistosoma mansoni protein kinase 0.102 0.2636 0.6662
Echinococcus granulosus MAM 0.0156 0.0211 0.0443
Loa Loa (eye worm) hypothetical protein 0.0121 0.0114 0.011
Schistosoma mansoni tyrosine kinase 0.0383 0.0848 0.2143
Onchocerca volvulus 0.0102 0.006 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase, putative 0.015 0.0196 0.1492
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0199 0.0331 0.0331
Echinococcus granulosus cyclin dependent kinase 5 0.0301 0.0618 0.1298
Schistosoma mansoni protein kinase 0.038 0.0841 0.2125
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0134 0.015 0.0314
Trypanosoma cruzi aurora B kinase, putative 0.0375 0.0826 0.3111
Schistosoma mansoni ephrin receptor 0.0102 0.006 0.0153
Plasmodium vivax protein kinase Crk2 0.0301 0.0618 0.4908
Schistosoma mansoni suppressor of cytokine signaling 0.0082 0.0004 0.0011
Brugia malayi Protein kinase domain containing protein 0.0802 0.2023 0.2037
Loa Loa (eye worm) AUR protein kinase 0.0375 0.0826 0.0829
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0102 0.006 0.0057
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0133 0.0147 0.0147
Trypanosoma cruzi casein kinase, putative 0.0273 0.0539 0.2029
Onchocerca volvulus 0.0194 0.0318 0.0317
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0241 0.045 0.1692
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1024 0.2647 1
Echinococcus granulosus protein tyrosine kinase 0.1491 0.3956 0.8316
Schistosoma mansoni serine/threonine protein kinase 0.0629 0.1539 0.389
Echinococcus granulosus retinal guanylyl cyclase 2 0.0102 0.006 0.0127
Brugia malayi Immunoglobulin I-set domain containing protein 0.0121 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0383 0.0848 0.0851
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Echinococcus granulosus growth factor receptor bound protein 2 0.0153 0.0203 0.0426
Loa Loa (eye worm) hypothetical protein 0.0458 0.1058 0.1063
Giardia lamblia Kinase, CK1 Casein kinase 0.0273 0.0539 0.2779
Onchocerca volvulus 0.0155 0.021 0.0208
Entamoeba histolytica protein kinase, putative 0.0549 0.1314 1
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0549 0.1314 0.496
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.006 0.0153
Brugia malayi Tyrosine-protein kinase abl-1 0.0421 0.0954 0.0959
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0717 0.1784 0.1796
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0528 0.1255 1
Echinococcus multilocularis transfer RNA-Phe 0.009 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0192 0.1062
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0543 0.1297 0.1297
Loa Loa (eye worm) hypothetical protein 0.0388 0.0862 0.0865
Trypanosoma cruzi casein kinase, putative 0.0273 0.0539 0.2029
Brugia malayi Plexin repeat family protein 0.0097 0.0046 0.0042
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0409 0.092 0.092
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0164 0.0234 0.0876
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.009 0.0028 0.006
Plasmodium falciparum protein kinase, putative 0.0102 0.006 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0098 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.021 0.0531
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0434 0.0992 0.0997
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Brugia malayi Protein kinase domain containing protein 0.3616 0.9915 1
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0308 0.0639 0.1342
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0132 0.0144 0.0363
Brugia malayi ephrin receptor 1 precursor 0.0102 0.006 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.0979 0.2474
Echinococcus granulosus c-Jun N-terminal kinases 0.1081 0.2805 0.5897
Echinococcus multilocularis protein kinase 0.0102 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Onchocerca volvulus 0.0184 0.029 0.0289
Echinococcus granulosus titin 0.0155 0.021 0.0441
Plasmodium falciparum calcium-dependent protein kinase 1 0.0205 0.0351 0.2776
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0537 0.1281 0.1281
Echinococcus granulosus tensin 0.0082 0.0004 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0234 0.0593
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Echinococcus granulosus tyrosine protein kinase Src42A 0.0409 0.092 0.1934
Echinococcus granulosus hemicentin 1 0.0121 0.0114 0.0239
Schistosoma mansoni tyrosine kinase 0.0295 0.0602 0.1522
Schistosoma mansoni serine/threonine protein kinase 0.0518 0.1228 0.3104
Trichomonas vaginalis TKL family protein kinase 0.0103 0.0065 0.0348
Loa Loa (eye worm) hypothetical protein 0.0297 0.0608 0.0609
Loa Loa (eye worm) hypothetical protein 0.0099 0.0053 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Trichomonas vaginalis AGC family protein kinase 0.0375 0.0826 0.4619
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0205 0.0351 0.2776
Loa Loa (eye worm) hypothetical protein 0.0388 0.0862 0.0865
Giardia lamblia Kinase, CMGC CLK 0.0528 0.1255 0.6933
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0102 0.006 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Echinococcus granulosus protein kinase c iota type 0.0199 0.0331 0.0696
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0258 0.0497 0.0497
Entamoeba histolytica protein kinase, putative 0.0147 0.0186 0.1416
Brugia malayi P38 map kinase family protein 2 0.1024 0.2647 0.2667
Schistosoma mansoni GTPase activating protein 0.0082 0.0004 0.0011
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0205 0.0351 0.2776
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0409 0.092 0.1934
Onchocerca volvulus Slit protein homolog 0.0126 0.0128 0.0125
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0102 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0103 0.0065 0.0493
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0241 0.045 0.1692
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.045 0.1138
Schistosoma mansoni protein tyrosine kinase 0.0102 0.006 0.0153
Loa Loa (eye worm) TK protein kinase 0.0616 0.1502 0.1511
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0375 0.0826 0.6281
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Onchocerca volvulus 0.0102 0.006 0.0057
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0528 0.1255 0.4736
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0198 0.0329 0.0327
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0102 0.006 0.006
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0082 0.0004 0.0009
Toxoplasma gondii histone kinase SNF1, putative 0.0164 0.0234 0.1849
Plasmodium falciparum casein kinase 1 0.0273 0.0539 0.4284
Loa Loa (eye worm) hypothetical protein 0.2055 0.5536 0.5581
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0528 0.1255 0.4736
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0181 0.0281 0.059
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0102 0.006 0.0153
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0301 0.0618 0.2325
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0409 0.092 0.1934
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni protein kinase 0.0417 0.0945 0.2388
Entamoeba histolytica hypothetical protein 0.0103 0.0065 0.0491
Loa Loa (eye worm) hypothetical protein 0.0309 0.0641 0.0642
Loa Loa (eye worm) hypothetical protein 0.0099 0.0051 0.0047
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0135 0.0284
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1081 0.2805 0.2826
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Schistosoma mansoni rap gtpase-activating protein 0.0194 0.0318 0.0803
Echinococcus granulosus casein kinase I alpha 0.0273 0.0539 0.1134
Entamoeba histolytica protein kinase domain containing protein 0.0167 0.0242 0.1842
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0267 0.0522 0.1321
Loa Loa (eye worm) hypothetical protein 0.0194 0.0318 0.0316
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0181 0.0281 0.0281
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0082 0.0004 0.0001
Giardia lamblia Kinase, CMGC CDK 0.0301 0.0618 0.3233
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0375 0.0826 0.6281
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0779 0.1958 0.4115
Loa Loa (eye worm) hypothetical protein 0.0236 0.0436 0.0435
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0831 0.2105 0.212
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica serine/threonine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0192 0.0486
Schistosoma mansoni protein kinase 0.0134 0.015 0.0378
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0194 0.0318 0.0316
Echinococcus multilocularis cyclin dependent kinase 0.0301 0.0618 0.0618
Echinococcus multilocularis rho associated protein kinase 0.0707 0.1756 0.1756
Echinococcus multilocularis casein kinase I alpha 0.0273 0.0539 0.0539
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0241 0.045 0.1692
Echinococcus multilocularis cyclin dependent kinase 9 0.0115 0.0098 0.0098
Trichomonas vaginalis STE family protein kinase 0.0134 0.015 0.0823
Loa Loa (eye worm) hypothetical protein 0.0267 0.0522 0.0523
Trypanosoma cruzi cdc2-related kinase 3 0.0301 0.0618 0.2325
Echinococcus granulosus tyrosine protein kinase Blk 0.0345 0.0742 0.1559
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0241 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0241 0.045 0.045
Onchocerca volvulus 0.0156 0.0211 0.0209
Echinococcus granulosus cyclin dependent kinase 9 0.0115 0.0098 0.0205
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0639 0.1614
Brugia malayi Protein kinase domain containing protein 0.0184 0.029 0.0288
Echinococcus multilocularis tensin 0.0082 0.0004 0.0004
Giardia lamblia Kinase, STE STE20 0.0134 0.015 0.0517
Brugia malayi Guanylyl cyclase protein 23 0.0102 0.006 0.0057
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0241 0.045 0.1692
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0204 0.0348 0.0347
Schistosoma mansoni tyrosine kinase 0.0409 0.092 0.2326
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0518 0.1227 0.9777
Echinococcus granulosus tyrosine protein kinase otk 0.0121 0.0114 0.0239
Schistosoma mansoni ephrin receptor 0.0114 0.0094 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0618 0.1561
Schistosoma mansoni hypothetical protein 0.0156 0.0211 0.0533
Schistosoma mansoni cell adhesion molecule 0.009 0.0028 0.0072
Echinococcus multilocularis protein kinase c epsilon type 0.0199 0.0331 0.0331
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1469 0.3895 0.8186
Schistosoma mansoni vam6/vps39 related 0.0194 0.0318 0.0803
Echinococcus multilocularis tyrosine protein kinase shark 0.0184 0.029 0.029
Echinococcus granulosus retinal guanylyl cyclase 2 0.0102 0.006 0.0127
Loa Loa (eye worm) AGC/AKT protein kinase 0.0165 0.0239 0.0236
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Plasmodium vivax glycogen synthase kinase 3, putative 0.0485 0.1135 0.9042
Echinococcus multilocularis signal transduction protein lnk realted 0.0082 0.0004 0.0004
Echinococcus multilocularis cyclin dependent kinase 9 0.0124 0.0122 0.0122
Onchocerca volvulus 0.3616 0.9915 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0121 0.0114 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0121 0.0114 0.011
Loa Loa (eye worm) AGC/PKN protein kinase 0.0149 0.0192 0.0189
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0273 0.0539 0.054
Trichomonas vaginalis STE family protein kinase 0.0134 0.015 0.0823
Echinococcus granulosus N chimaerin 0.0132 0.0144 0.0302
Loa Loa (eye worm) RGC/RGC protein kinase 0.0102 0.006 0.0057
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Loa Loa (eye worm) TK/CSK protein kinase 0.0102 0.006 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0375 0.0826 0.0826
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0629 0.1539 0.1549
Loa Loa (eye worm) hypothetical protein 0.0279 0.0556 0.0556
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0139 0.1055
Entamoeba histolytica tyrosin kinase, putative 0.013 0.0139 0.1055
Entamoeba histolytica hypothetical protein 0.0103 0.0065 0.0491
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0267 0.0522 0.0522
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Entamoeba histolytica ankyrin repeat protein 0.0102 0.006 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0167 0.0242 0.0905
Brugia malayi cyclin-dependent kinase 7 homolog 0.0412 0.0929 0.0933
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica serine/threonine kinase, putative 0.0102 0.006 0.046
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0485 0.1135 0.4283
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0537 0.1281 0.1281
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.045 0.1138
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0164 0.0234 0.0232
Echinococcus granulosus SH2 motif 0.0082 0.0004 0.0009
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.045
Echinococcus granulosus NDR protein kinase 0.0149 0.0192 0.0404
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Echinococcus granulosus ephrin type A receptor 4 A 0.0102 0.006 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.1255 0.3173
Schistosoma mansoni cell adhesion molecule 0.0321 0.0674 0.1705
Trichomonas vaginalis STE family protein kinase 0.0717 0.1784 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.102 0.2636 0.554
Loa Loa (eye worm) AGC/PKA protein kinase 0.0241 0.045 0.045
Brugia malayi Immunoglobulin I-set domain containing protein 0.0204 0.0348 0.0347
Trichomonas vaginalis STE family protein kinase 0.0134 0.015 0.0823
Echinococcus multilocularis tyrosine protein kinase Abl 0.0508 0.1199 0.1199
Trichomonas vaginalis STE family protein kinase 0.0134 0.015 0.0823
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0241 0.045 0.3573
Leishmania major protein kinase, putative 0.0528 0.1255 0.4736
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0573 0.1381 0.2902
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Schistosoma mansoni hypothetical protein 0.009 0.0028 0.0072
Schistosoma mansoni serine/threonine kinase 0.0149 0.0192 0.0486
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0121 0.0114 0.011
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0102 0.006 0.006
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0241 0.045 0.3573
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0082 0.0004 0.0004
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0543 0.1297 0.2725
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Echinococcus multilocularis serine:threonine protein kinase N2 0.0149 0.0192 0.0192
Echinococcus granulosus tyrosine protein kinase Src42A 0.025 0.0475 0.0999
Echinococcus granulosus dual specificity 0.0549 0.1314 0.2763
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0528 0.1255 0.4736
Schistosoma mansoni cell adhesion molecule 0.009 0.0028 0.0072
Plasmodium vivax serine/threonine kinase-1, putative 0.0528 0.1255 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0102 0.006 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0331 0.0837
Loa Loa (eye worm) hypothetical protein 0.0121 0.0114 0.011
Echinococcus granulosus casein kinase I alpha 0.0273 0.0539 0.1134
Brugia malayi Furin-like cysteine rich region family protein 0.0295 0.0602 0.0603
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.0947
Onchocerca volvulus 0.0273 0.0539 0.0541
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0102 0.006 0.0153
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0383 0.085 0.0853
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0485 0.1135 0.2386
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Schistosoma mansoni hypothetical protein 0.0082 0.0004 0.0011
Echinococcus granulosus casein kinase I delta 0.0273 0.0539 0.1134
Plasmodium vivax tyrosine kinase-like protein, putative 0.0102 0.006 0.0459
Loa Loa (eye worm) hypothetical protein 0.009 0.0028 0.0024
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0121 0.0114 0.011
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0301 0.0618 0.0619
Plasmodium falciparum protein kinase 5 0.0301 0.0618 0.4908
Brugia malayi hypothetical protein 0.0099 0.0053 0.0049
Loa Loa (eye worm) hypothetical protein 0.0126 0.0128 0.0124
Echinococcus granulosus dual specificity mitogen activated protein 0.0717 0.1784 0.3749
Loa Loa (eye worm) hypothetical protein 0.0267 0.0522 0.0523
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0549 0.1314 0.496
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0409 0.092 0.092
Brugia malayi Protein kinase domain containing protein 0.0184 0.029 0.0288
Echinococcus multilocularis mitogen activated protein kinase 11 0.1024 0.2647 0.2647
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0623 0.1522 0.1522
Echinococcus multilocularis slit 2 protein 0.0126 0.0128 0.0128
Echinococcus granulosus neuroglian 0.0133 0.0147 0.0309
Trypanosoma cruzi cdc2-related kinase 1 0.0301 0.0618 0.2325
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0205 0.0351 0.0351
Echinococcus multilocularis tyrosine protein kinase csk 0.0102 0.006 0.006
Loa Loa (eye worm) TK/ROR protein kinase 0.0181 0.0281 0.0279
Brugia malayi RhoGAP domain containing protein 0.0132 0.0144 0.014
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Leishmania major protein kinase, putative 0.0528 0.1255 0.4736
Trypanosoma brucei Flagellum attachment zone protein 20 0.0102 0.006 0.0218
Brugia malayi protein kinase C3,putative 0.0114 0.0096 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0028 0.0024
Plasmodium falciparum calcium-dependent protein kinase 5 0.0205 0.0351 0.2776
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0205 0.0351 0.2776
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Echinococcus granulosus defective proboscis extension response 0.0267 0.0522 0.1098
Entamoeba histolytica p21-activated kinase 0.015 0.0196 0.1492
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Echinococcus granulosus SH2 motif 0.0082 0.0004 0.0009
Brugia malayi C1-like domain containing protein 0.0383 0.085 0.0853
Echinococcus multilocularis protein KINase family member (kin 25) 0.0383 0.0848 0.0848
Echinococcus granulosus neuroglian 0.0345 0.0743 0.1561
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0258 0.0498 0.1046
Echinococcus multilocularis cyclin dependent kinase 1 0.0301 0.0618 0.0618
Schistosoma mansoni tyrosine protein kinase 0.0102 0.006 0.0153
Entamoeba histolytica cysteine surface protein, putative 0.0102 0.006 0.046
Echinococcus multilocularis tyrosine protein kinase otk 0.0121 0.0114 0.0114
Echinococcus multilocularis SH2 domain containing protein 7 0.0082 0.0004 0.0004
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0102 0.006 0.0153
Entamoeba histolytica hypothetical protein 0.0103 0.0065 0.0491
Loa Loa (eye worm) TK/EPH protein kinase 0.0102 0.006 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0192 0.0486
Echinococcus granulosus roundabout 2 0.0133 0.0147 0.0309
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0102 0.006 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0234 0.0593
Brugia malayi serine/threonine protein kinase 6 0.0375 0.0826 0.0829
Onchocerca volvulus 0.0485 0.1135 0.1142
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0102 0.006 0.0127
Entamoeba histolytica tyrosin kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni serine/threonine RGC 0.0102 0.006 0.0153
Entamoeba histolytica protein kinase, putative 0.0149 0.0192 0.1462
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0929 0.238 0.2397
Onchocerca volvulus 0.0184 0.029 0.0289
Trichomonas vaginalis STE family protein kinase 0.0717 0.1784 1
Entamoeba histolytica protein kinase, putative 0.0485 0.1135 0.8637
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Echinococcus multilocularis tyrosine protein kinase Src42A 0.025 0.0475 0.0475
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Brugia malayi protein-tyrosine kinase 0.0345 0.0742 0.0744
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1081 0.2805 0.2805
Trichomonas vaginalis AGC family protein kinase 0.0518 0.1227 0.6875
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Echinococcus multilocularis lachesin 0.0121 0.0114 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Plasmodium vivax tyrosine kinase-like protein, putative 0.0102 0.006 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0205 0.0351 0.1952
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0102 0.006 0.0127
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0409 0.092 0.092
Echinococcus multilocularis tyrosine protein kinase csk 0.0102 0.006 0.006
Schistosoma mansoni protein kinase 0.0693 0.1718 0.4343
Echinococcus granulosus tyrosine protein kinase Fyn 0.0409 0.092 0.1934
Echinococcus multilocularis plexin a4 0.0125 0.0125 0.0125
Schistosoma mansoni tensin 0.0082 0.0004 0.0011
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0134 0.015 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0618 0.3451
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0451 0.1039 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Trypanosoma cruzi casein kinase, putative 0.0273 0.0539 0.2029
Entamoeba histolytica protein kinase domain containing protein 0.0485 0.1135 0.8637
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0149 0.0192 0.0404
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis STE family protein kinase 0.0518 0.1227 0.6875
Entamoeba histolytica protein kinase domain containing protein 0.0375 0.0826 0.6281
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.009 0.0028 0.0024
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.0947
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0308 0.0639 0.0639
Echinococcus granulosus receptor type guanylyl cyclase 0.0102 0.006 0.0127
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Onchocerca volvulus 0.0097 0.0046 0.0043
Schistosoma mansoni tyrosine kinase 0.0223 0.04 0.101
Brugia malayi Protein kinase domain containing protein 0.0531 0.1263 0.127
Entamoeba histolytica casein kinase, putative 0.0273 0.0539 0.4104
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0082 0.0004 0.0004
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0084 0.001 0.0042
Onchocerca volvulus 0.0082 0.0004 0.0001
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0241 0.045 0.3573
Loa Loa (eye worm) hypothetical protein 0.0281 0.0562 0.0563
Echinococcus granulosus lachesin 0.0121 0.0114 0.0239
Brugia malayi Protein kinase c protein 2 0.0114 0.0096 0.0092
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0132 0.0144 0.0144
Brugia malayi Peroxidasin 0.0122 0.0118 0.0114
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Giardia lamblia Kinase, NEK 0.0518 0.1227 0.6771
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0102 0.006 0.0323
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0132 0.0144 0.0302
Brugia malayi Protein kinase domain containing protein 0.0114 0.0096 0.0092
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0779 0.1958 0.4948
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0082 0.0004 0.0011
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0717 0.1784 0.6736
Entamoeba histolytica PH domain containing protein kinase, putative 0.0081 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0121 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0279 0.0556 0.0556
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0779 0.1958 0.1972
Brugia malayi serine/threonine-protein kinase PAK 7 0.0871 0.2216 0.2232
Schistosoma mansoni shc transforming protein 0.0082 0.0004 0.0011
Echinococcus multilocularis neuroglian 0.0345 0.0743 0.0743
Schistosoma mansoni tensin-related 0.0082 0.0004 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0485 0.1135 0.6358
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trypanosoma brucei Pseudokinase, putative 0.0102 0.006 0.0218
Trichomonas vaginalis CK1 family protein kinase 0.0273 0.0539 0.3013
Echinococcus multilocularis tyrosine protein kinase 0.0102 0.006 0.006
Brugia malayi integrin-linked kinase 0.0102 0.006 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0176 0.0269 0.0565
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0102 0.006 0.0323
Schistosoma mansoni serine/threonine protein kinase 0.0802 0.2023 0.5114
Schistosoma mansoni protein kinase 0.0329 0.0697 0.1761
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0102 0.006 0.006
Loa Loa (eye worm) AUR protein kinase 0.0375 0.0826 0.0829
Echinococcus granulosus tyrosine protein kinase Fyn 0.0409 0.092 0.1934
Echinococcus multilocularis MAM 0.0156 0.0211 0.0211
Plasmodium falciparum calcium-dependent protein kinase 3 0.0205 0.0351 0.2776
Entamoeba histolytica PH domain containing protein kinase, putative 0.0081 0.0003 0.0022
Entamoeba histolytica protein kinase, putative 0.0549 0.1314 1
Echinococcus multilocularis twitchin 0.0143 0.0177 0.0177
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0173 0.0259 0.2046
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0205 0.0351 0.0737
Echinococcus multilocularis growth factor receptor bound protein 2 0.0146 0.0183 0.0183
Onchocerca volvulus 0.0102 0.006 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0164 0.0234 0.0876
Loa Loa (eye worm) hypothetical protein 0.0729 0.182 0.1832
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1024 0.2647 1
Echinococcus multilocularis SHC transforming protein 3 0.0082 0.0004 0.0004
Entamoeba histolytica protein kinase, putative 0.0375 0.0826 0.6281
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0102 0.006 0.0127
Plasmodium vivax calcium-dependent protein kinase, putative 0.0205 0.0351 0.2776
Echinococcus granulosus activin receptor type 0.1777 0.4758 1
Loa Loa (eye worm) hypothetical protein 0.0269 0.0529 0.0529
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Echinococcus granulosus casein kinase I alpha 0.0273 0.0539 0.1134
Schistosoma mansoni suppressor of cytokine signaling 0.0082 0.0004 0.0011
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0717 0.1784 0.6736
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0102 0.006 0.046
Echinococcus granulosus tyrosine protein kinase Btk29A 0.098 0.2522 0.5301
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0102 0.006 0.0057
Echinococcus multilocularis dual specificity mitogen activated protein 0.0717 0.1784 0.1784
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0865 0.22 0.22
Brugia malayi probable protein kinase 0.0522 0.124 0.1246
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0485 0.1135 0.1135
Schistosoma mansoni kinase 0.0115 0.0098 0.0247
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0528 0.1255 0.4736
Echinococcus multilocularis protein kinase 0.0102 0.006 0.006
Brugia malayi Cam kinase protein 1 0.0205 0.0351 0.0349
Brugia malayi Protein kinase domain containing protein 0.0831 0.2105 0.212
Echinococcus granulosus hypothetical protein 0.0082 0.0004 0.0009
Echinococcus granulosus nephrin 0.009 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0484 0.1133 0.1139
Echinococcus multilocularis SH2 motif 0.0082 0.0004 0.0004
Echinococcus multilocularis SH2 motif 0.0082 0.0004 0.0004
Plasmodium falciparum protein kinase, putative 0.0102 0.006 0.0459
Entamoeba histolytica hypothetical protein 0.0549 0.1314 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0102 0.006 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0826 0.2087
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni hypothetical protein 0.0194 0.0318 0.0803
Entamoeba histolytica protein kinase, putative 0.0081 0.0003 0.0022
Echinococcus granulosus tyrosine protein kinase ABL1 0.0865 0.22 0.4625
Loa Loa (eye worm) hypothetical protein 0.009 0.0028 0.0024
Schistosoma mansoni atypical protein kinase C 0.0199 0.0331 0.0837
Schistosoma mansoni tyrosine kinase 0.0409 0.092 0.2326
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0409 0.092 0.092
Echinococcus granulosus SH2 domain containing protein 7 0.0082 0.0004 0.0009
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0205 0.0351 0.2776
Echinococcus granulosus serine:threonine protein kinase TAO1 0.1312 0.3454 0.726
Entamoeba histolytica protein kinase, putative 0.0134 0.015 0.1138
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0518 0.1227 0.9777
Entamoeba histolytica protein kinase, putative 0.0165 0.0239 0.1816
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Onchocerca volvulus 0.0184 0.029 0.0289
Schistosoma mansoni hypothetical protein 0.0102 0.006 0.0153
Schistosoma mansoni tyrosine kinase 0.0193 0.0317 0.08
Loa Loa (eye worm) hypothetical protein 0.0194 0.0318 0.0316
Trypanosoma cruzi cdc2-related kinase 1 0.0301 0.0618 0.2325
Echinococcus granulosus retinal guanylyl cyclase 2 0.0102 0.006 0.0127
Brugia malayi hypothetical protein 0.0102 0.006 0.0057
Echinococcus granulosus tyrosine protein kinase HCK 0.0263 0.0512 0.1076
Echinococcus multilocularis Immunoglobulin 0.0267 0.0522 0.0522
Entamoeba histolytica ankyrin repeat protein 0.0102 0.006 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Onchocerca volvulus 0.0642 0.1574 0.1585
Schistosoma mansoni serine/threonine-protein kinase 0.0081 0.0003 0.0007
Loa Loa (eye worm) TK/RYK protein kinase 0.0102 0.006 0.0057
Schistosoma mansoni nephrin 0.0357 0.0776 0.1962
Echinococcus granulosus serine:threonine kinase SAD 1 0.0164 0.0234 0.0493
Echinococcus multilocularis protein kinase shaggy 0.0485 0.1135 0.1135
Toxoplasma gondii protein kinase domain-containing protein 0.0102 0.006 0.0459
Echinococcus multilocularis casein kinase I alpha 0.0273 0.0539 0.0539
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0488 0.1142 0.1148
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0779 0.1958 0.1958
Brugia malayi Immunoglobulin I-set domain containing protein 0.0133 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0194 0.0318 0.0803
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0164 0.0234 0.0876
Echinococcus granulosus dual specificity protein kinase clk2 0.0528 0.1255 0.2638
Echinococcus granulosus tyrosine kinase 0.0102 0.006 0.0127
Onchocerca volvulus 0.0082 0.0004 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni cell adhesion molecule 0.0133 0.0147 0.0372
Schistosoma mansoni roundabout 0.0121 0.0114 0.0288
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Echinococcus granulosus peroxidasin 0.0122 0.0118 0.0248
Echinococcus multilocularis integrin linked protein kinase 0.0102 0.006 0.006
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0528 0.1255 0.4736
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Echinococcus multilocularis c src tyrosine kinase 0.0248 0.0469 0.0469
Brugia malayi Hr1 repeat family protein 0.0149 0.0192 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.1081 0.2805 0.7091
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Schistosoma mansoni protein kinase 0.0273 0.0539 0.1364
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni tensin 0.0082 0.0004 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0409 0.092 0.1934
Entamoeba histolytica receptor protein kinase, putative 0.0102 0.006 0.046
Giardia lamblia Kinase, STE STE20 0.0717 0.1784 1
Onchocerca volvulus 0.1059 0.2745 0.2766
Echinococcus multilocularis neuroglian 0.0133 0.0147 0.0147
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0802 0.2023 0.4251
Loa Loa (eye worm) AGC/NDR protein kinase 0.0149 0.0192 0.0189
Echinococcus multilocularis hemicentin 1 0.0121 0.0114 0.0114
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0082 0.0004 0.0001
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0102 0.006 0.006
Echinococcus granulosus contactin 0.0133 0.0147 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0539 0.1364
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Echinococcus granulosus cyclin dependent kinase 9 0.0124 0.0122 0.0257
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0259 0.05 0.105
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0149 0.0192 0.0192
Giardia lamblia Kinase, CAMK CAMKL 0.0173 0.0259 0.1153
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Loa Loa (eye worm) hypothetical protein 0.0122 0.0118 0.0114
Echinococcus granulosus cyclin dependent kinase 19 0.0929 0.238 0.5002
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0409 0.092 0.092
Echinococcus multilocularis tensin 0.0082 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0248 0.0469 0.1185
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0102 0.006 0.0459
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0167 0.0242 0.0905
Toxoplasma gondii AGC kinase 0.0241 0.045 0.3573
Entamoeba histolytica serine/threonine kinase, putative 0.0102 0.006 0.046
Echinococcus multilocularis tyrosine kinase 0.0102 0.006 0.006
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0549 0.1314 0.1322
Echinococcus granulosus roundabout 2 0.0399 0.0895 0.1881
Schistosoma mansoni titin 0.0121 0.0114 0.0288
Brugia malayi Protein kinase domain containing protein 0.0338 0.0722 0.0724
Trichomonas vaginalis protein tyrosine kinase, putative 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0335 0.0714 0.0716
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0134 0.015 0.015
Echinococcus multilocularis protein tyrosine kinase 0.1491 0.3956 0.3956
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0573 0.1381 0.1389
Loa Loa (eye worm) hypothetical protein 0.0463 0.1074 0.1079
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.009 0.0028 0.0024
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0102 0.006 0.0153
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.1312 0.3454 0.3454
Echinococcus multilocularis Immunoglobulin 0.0267 0.0522 0.0522
Brugia malayi Immunoglobulin I-set domain containing protein 0.0133 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0268 0.0527 0.0527
Echinococcus multilocularis cyclin dependent kinase 7 0.0403 0.0904 0.0904
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0528 0.1255 0.4736
Schistosoma mansoni nephrin 0.0133 0.0147 0.0372
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0205 0.0351 0.0349
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0194 0.0318 0.0668
Echinococcus granulosus mitogen activated protein kinase 14 0.1024 0.2647 0.5564
Echinococcus granulosus TGF-beta receptor type-1 0.038 0.0841 0.1767
Leishmania major protein kinase A catalytic subunit isoform 1 0.0241 0.045 0.1692
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0082 0.0004 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0028 0.0024
Schistosoma mansoni tensin 0.0082 0.0004 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0258 0.0497 0.3781
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.045
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Loa Loa (eye worm) hypothetical protein 0.0281 0.0562 0.0563
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Giardia lamblia Kinase, NEK 0.0518 0.1227 0.6771
Echinococcus multilocularis SH2 motif 0.0082 0.0004 0.0004
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni tyrosine kinase 0.1491 0.3956 1
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0779 0.1958 0.1971
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0177 0.0447
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Echinococcus granulosus NCK adaptor protein 0.0146 0.0183 0.0385
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0587 0.1422 0.143
Echinococcus granulosus roundabout 2 0.0133 0.0147 0.0309
Schistosoma mansoni plexin 0.0097 0.0046 0.0117
Entamoeba histolytica serine/threonine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni serine/threonine-protein kinase 0.0081 0.0003 0.0007
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0133 0.0147 0.0144
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Entamoeba histolytica PH domain containing protein kinase, putative 0.0081 0.0003 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0149 0.0192 0.0404
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Echinococcus multilocularis epidermal growth factor receptor 0.0295 0.0602 0.0602
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0102 0.006 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0717 0.1784 0.6736
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0121 0.0114 0.011
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0082 0.0004 0.0004
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0194 0.0318 0.1191
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0149 0.0192 0.0189
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0102 0.006 0.0057
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0485 0.1135 0.1141
Echinococcus granulosus casein kinase i 0.0273 0.0539 0.1134
Loa Loa (eye worm) hypothetical protein 0.0297 0.0608 0.0609
Plasmodium vivax casein kinase 1, putative 0.0273 0.0539 0.4284
Toxoplasma gondii AGC kinase 0.0149 0.0192 0.1511
Leishmania major casein kinase, putative 0.0273 0.0539 0.2029
Loa Loa (eye worm) AUR protein kinase 0.0375 0.0826 0.0829
Brugia malayi casein kinase 1, delta 0.0273 0.0539 0.054
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Trichomonas vaginalis AGC family protein kinase 0.0158 0.0217 0.1201
Echinococcus granulosus beta-adrenergic receptor kinase 0.0121 0.0115 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0351 0.0886
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0639 0.1614
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Brugia malayi casein kinase I 0.0273 0.0539 0.054
Schistosoma mansoni protein kinase 0.0693 0.1718 0.4343
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.0904 0.2286
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0205 0.0351 0.0737
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0102 0.006 0.0153
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Echinococcus multilocularis rac serine:threonine kinase 0.0081 0.0003 0.0003
Plasmodium falciparum calcium-dependent protein kinase 2 0.0205 0.0351 0.2776
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0485 0.1135 0.287
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0102 0.006 0.0057
Echinococcus multilocularis FL cytokine receptor 0.0102 0.006 0.006
Echinococcus multilocularis peroxidasin 0.0122 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0236 0.0436 0.0435
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0485 0.1135 0.8637
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0802 0.2023 0.2037
Trichomonas vaginalis CK1 family protein kinase 0.0273 0.0539 0.3013
Entamoeba histolytica casein kinase 1, putative 0.0273 0.0539 0.4104
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0629 0.1539 0.1549
Loa Loa (eye worm) TK/EGFR protein kinase 0.0295 0.0602 0.0603
Echinococcus granulosus protein kinase 0.0329 0.0697 0.1464
Echinococcus multilocularis dual specificity 0.0549 0.1314 0.1314
Echinococcus multilocularis mitogen activated protein kinase 11 0.1024 0.2647 0.2647
Echinococcus granulosus protein kinase shaggy 0.0485 0.1135 0.2386
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0693 0.1718 0.3611
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0149 0.0192 0.0189
Onchocerca volvulus 0.0167 0.0244 0.0243
Onchocerca volvulus 0.0082 0.0004 0.0001
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1024 0.2647 0.2667
Trypanosoma brucei protein kinase, putative 0.0485 0.1135 0.4283
Brugia malayi Variant SH3 domain containing protein 0.0132 0.0144 0.014
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0458 0.1058 0.2224
Brugia malayi Temporarily assigned gene name protein 59 0.0194 0.0318 0.0316
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Echinococcus multilocularis tyrosine protein kinase pr2 0.0102 0.006 0.006
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0205 0.0351 0.1315
Leishmania major protein kinase A catalytic subunit isoform 2 0.0241 0.045 0.1692
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0135 0.0135
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0573 0.1381 0.1389
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0205 0.0351 0.0349
Echinococcus granulosus Immunoglobulin 0.0267 0.0522 0.1098
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Onchocerca volvulus 0.0184 0.029 0.0289
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0102 0.006 0.0057
Echinococcus multilocularis cyclin dependent kinase 1 0.0301 0.0618 0.0618
Entamoeba histolytica hypothetical protein, conserved 0.0102 0.006 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Echinococcus granulosus natriuretic peptide receptor 1 0.0102 0.006 0.0127
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Giardia lamblia Kinase, AGC AKT 0.0434 0.0992 0.5407
Brugia malayi SH2 domain containing protein 0.0184 0.029 0.0288
Schistosoma mansoni hemicentin 0.009 0.0028 0.0072
Echinococcus granulosus TGF beta receptor type 1 0.038 0.0841 0.1767
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0082 0.0004 0.0004
Onchocerca volvulus 0.0102 0.006 0.0057
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Schistosoma mansoni titin 0.009 0.0028 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Trypanosoma brucei cdc2-related kinase 3 0.0301 0.0618 0.2325
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0121 0.0114 0.0114
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.0947
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0114 0.0096 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni tyrosine kinase 0.0531 0.1263 0.3193
Brugia malayi hypothetical protein 0.0194 0.0318 0.0316
Loa Loa (eye worm) SRC-1 0.0409 0.092 0.0924
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Echinococcus multilocularis receptor type guanylyl cyclase 0.0102 0.006 0.006
Echinococcus multilocularis casein kinase I delta 0.0273 0.0539 0.0539
Plasmodium falciparum NIMA related kinase 1 0.0518 0.1227 0.9777
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Onchocerca volvulus 0.0184 0.029 0.0289
Leishmania major protein kinase, putative 0.0205 0.0351 0.1315
Giardia lamblia Aurora kinase 0.0375 0.0826 0.444
Loa Loa (eye worm) IKK protein kinase 0.3616 0.9915 1
Brugia malayi plexin A 0.0125 0.0125 0.0121
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus serine/threonine protein kinase 0.0081 0.0003 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0121 0.0114 0.011
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.045 0.1138
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Trypanosoma brucei cdc2-related kinase 1 0.0301 0.0618 0.2325
Echinococcus granulosus tyrosine protein kinase csk 0.0102 0.006 0.0127
Echinococcus granulosus plexin a4 0.0125 0.0125 0.0262
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0549 0.1314 0.496
Echinococcus granulosus tyrosine protein kinase Srms 0.0184 0.029 0.061
Brugia malayi hypothetical protein 0.1312 0.3454 0.3481
Loa Loa (eye worm) hypothetical protein 0.0156 0.0211 0.0208
Toxoplasma gondii protein kinase 0.0102 0.006 0.0459
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni protein kinase 0.0623 0.1522 0.3847
Schistosoma mansoni septate junction protein 0.0121 0.0114 0.0288
Brugia malayi Protein kinase domain containing protein 0.0623 0.1522 0.1531
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0375 0.0826 0.6569
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Onchocerca volvulus 0.0269 0.0529 0.053
Loa Loa (eye worm) hypothetical protein 0.0484 0.1133 0.1139
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0518 0.1228 0.2581
Brugia malayi Protein kinase domain 0.0134 0.015 0.0146
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0115 0.029
Schistosoma mansoni serine/threonine protein kinase 0.1312 0.3454 0.8731
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0375 0.0826 0.6281
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Echinococcus multilocularis TGF beta receptor type 1 0.038 0.0841 0.0841
Schistosoma mansoni tyrosine kinase 0.0193 0.0317 0.08
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0102 0.006 0.0459
Trypanosoma cruzi cdc2-related kinase 3 0.0301 0.0618 0.2325
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0134 0.015 0.0314
Schistosoma mansoni thyroid hormone receptor 0.0151 0.0198 0.0501
Loa Loa (eye worm) hypothetical protein 0.0156 0.0211 0.0208
Trichomonas vaginalis protein kinase atn1, putative 0.0102 0.006 0.0323
Echinococcus granulosus cyclin dependent kinase 7 0.0403 0.0904 0.1901
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0241 0.045 0.2513
Loa Loa (eye worm) hypothetical protein 0.0184 0.029 0.0288
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Echinococcus multilocularis serine threonine protein kinase 0.0149 0.0192 0.0192
Brugia malayi protein kinase C II. 0.0199 0.0331 0.033
Echinococcus multilocularis calcium dependent protein kinase 0.0141 0.0169 0.0169
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Onchocerca volvulus 0.0319 0.0668 0.067
Loa Loa (eye worm) hypothetical protein 0.0347 0.0747 0.0749
Trypanosoma brucei protein kinase, putative 0.0167 0.0242 0.0905
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0192 0.0486
Giardia lamblia Kinase, NEK 0.0518 0.1227 0.6771
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0309 0.0641 0.1348
Plasmodium falciparum glycogen synthase kinase 3 0.0485 0.1135 0.9042
Echinococcus multilocularis dual specificity protein kinase clk2 0.0528 0.1255 0.1255
Schistosoma mansoni tyrosine kinase 0.0171 0.0254 0.0641
Plasmodium falciparum serine/threonine protein kinase KIN 0.0164 0.0234 0.1849
Onchocerca volvulus 0.0124 0.0124 0.0121
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0587 0.1422 0.2988
Trichomonas vaginalis AGC family protein kinase 0.0375 0.0826 0.4619
Echinococcus granulosus epidermal growth factor receptor 0.0295 0.0602 0.1266
Echinococcus granulosus activated cdc42 kinase 1 0.0831 0.2105 0.4425
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0537 0.1281 0.2693
Echinococcus multilocularis heat shock protein 70 0.0102 0.006 0.006
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0102 0.006 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0549 0.1314 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0133 0.0147 0.0147
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2061 0.5554 0.56
Brugia malayi SRC-1 0.0409 0.092 0.0924
Echinococcus granulosus insulin receptor 0.0531 0.1263 0.2655
Echinococcus granulosus SHC transforming protein 3 0.0082 0.0004 0.0009
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0147 0.0186 0.1416
Loa Loa (eye worm) hypothetical protein 0.0319 0.0668 0.0669
Brugia malayi Protein kinase domain containing protein 0.2061 0.5554 0.56
Trypanosoma brucei SNF1-related protein kinases, putative 0.0164 0.0234 0.0876
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0334 0.071 0.0712
Giardia lamblia Kinase, CAMK CAMKL 0.0173 0.0259 0.1153
Loa Loa (eye worm) hypothetical protein 0.0279 0.0556 0.0556
Echinococcus multilocularis roundabout 2 0.0399 0.0895 0.0895
Loa Loa (eye worm) hypothetical protein 0.0297 0.0608 0.0609
Echinococcus granulosus tyrosine protein kinase Src64B 0.0409 0.092 0.1934
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0132 0.0144 0.0363
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Plasmodium falciparum protein kinase, putative 0.0167 0.0242 0.191
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0102 0.006 0.0127
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0273 0.0539 0.2029
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0409 0.092 0.092
Brugia malayi p70 ribosomal S6 kinase beta 0.0149 0.0192 0.0189
Echinococcus granulosus titin 0.0155 0.021 0.0441
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0115 0.0098 0.0094
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0102 0.006 0.0057
Brugia malayi Protein kinase domain containing protein 0.0929 0.238 0.2397
Schistosoma mansoni tyrosine kinase 0.0295 0.0602 0.1522
Brugia malayi Protein kinase domain containing protein 0.0258 0.0497 0.0497
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica PH domain containing protein kinase, putative 0.0258 0.0497 0.3781
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase, putative 0.0081 0.0003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) AGC/PKA protein kinase 0.0241 0.045 0.045
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0345 0.0742 0.1559
Echinococcus multilocularis kinase suppressor of Ras 1 0.0102 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0184 0.029 0.029
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0301 0.0618 0.0619
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus suppressor of cytokine signaling 7 0.0082 0.0004 0.0009
Onchocerca volvulus 0.0102 0.006 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0133 0.0147 0.0144
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0409 0.092 0.092
Entamoeba histolytica protein kinase , putative 0.0375 0.0826 0.6281
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0618 0.1561
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus tyrosine kinase 0.0184 0.029 0.061
Trypanosoma cruzi casein kinase, putative 0.0273 0.0539 0.2029
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.006 0.0153
Echinococcus multilocularis 0.0329 0.0697 0.0697
Echinococcus granulosus expressed conserved protein 0.0082 0.0004 0.0009
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0184 0.029 0.061
Schistosoma mansoni protein kinase C mu 0.0383 0.085 0.2147
Echinococcus multilocularis titin 0.0155 0.021 0.021
Schistosoma mansoni growth factor receptor-bound protein 0.0153 0.0203 0.0513
Brugia malayi Variant SH3 domain containing protein 0.0146 0.0183 0.018
Entamoeba histolytica hypothetical protein 0.0102 0.006 0.046
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0194 0.0318 0.1191
Entamoeba histolytica tyrosin kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase, putative 0.015 0.0196 0.1492
Onchocerca volvulus 0.0082 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Onchocerca volvulus 0.0184 0.029 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Echinococcus multilocularis tyrosine protein kinase Srms 0.0345 0.0742 0.0742
Brugia malayi Protein kinase domain containing protein 0.0528 0.1255 0.1262
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Loa Loa (eye worm) RGC/RGC protein kinase 0.0102 0.006 0.0057
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0102 0.006 0.0057
Echinococcus multilocularis ephrin type A receptor 4 A 0.0102 0.006 0.006
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0133 0.0147 0.0147
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0485 0.1135 0.4283
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0267 0.0522 0.1321
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Schistosoma mansoni protein kinase 0.102 0.2636 0.6662
Brugia malayi Stress-activated protein kinase jnk-1 0.1081 0.2805 0.2826
Schistosoma mansoni serine/threonine protein kinase 0.0707 0.1756 0.4438
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Brugia malayi Protein kinase domain containing protein 0.0184 0.029 0.0288
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Schistosoma mansoni hypothetical protein 0.0128 0.0135 0.0341
Echinococcus granulosus protein kinase 0.0102 0.006 0.0127
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0134 0.015 0.015
Echinococcus granulosus cyclin dependent kinase 1 0.0301 0.0618 0.1298
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus multilocularis 0.0082 0.0004 0.0004
Schistosoma mansoni protein kinase 0.0375 0.0826 0.2087
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0199 0.0331 0.033
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0167 0.0242 0.191
Onchocerca volvulus 0.0082 0.0004 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.02 0.0505
Loa Loa (eye worm) projectin 0.009 0.0028 0.0024
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0623 0.1522 0.3199
Trichomonas vaginalis AGC family protein kinase 0.0375 0.0826 0.4619
Entamoeba histolytica protein kinase, putative 0.0263 0.0512 0.3894
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0102 0.006 0.0218
Echinococcus granulosus cyclin dependent kinase 0.0301 0.0618 0.1298
Echinococcus granulosus calcium dependent protein kinase 0.0141 0.0169 0.0355
Trypanosoma brucei aurora B kinase 0.0375 0.0826 0.3111
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0208 0.0358 0.1342
Entamoeba histolytica protein kinase, putative 0.0081 0.0003 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0028 0.0024
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0102 0.006 0.006
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0258 0.0497 0.0497
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0345 0.0742 0.0742
Brugia malayi Protein kinase domain containing protein 0.0149 0.0192 0.0189
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0417 0.0945 0.0949
Schistosoma mansoni protein kinase 0.0522 0.124 0.3133
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0334 0.0711 0.0712
Schistosoma mansoni growth factor receptor-bound protein 0.0146 0.0183 0.0463
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0518 0.1228 0.1235
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0109 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0205 0.0351 0.0349
Loa Loa (eye worm) TK/Met protein kinase 0.0102 0.006 0.0057
Echinococcus granulosus serine:threonine protein kinase N2 0.0149 0.0192 0.0404
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0556 0.0556
Schistosoma mansoni tyrosine kinase 0.0537 0.1281 0.3239
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0205 0.0351 0.0351
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0295 0.0602 0.1266
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0194 0.0318 0.1191
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0184 0.029 0.2208
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0618 0.3451
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Brugia malayi hypothetical protein 0.0184 0.029 0.0288
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0082 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0156 0.0211 0.0208
Echinococcus multilocularis transfer RNA-Thr 0.0831 0.2105 0.2105
Brugia malayi Protein kinase domain containing protein 0.1508 0.4003 0.4034
Brugia malayi C-terminal src kinase protein 1 0.0102 0.006 0.0057
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.038 0.0841 0.0841
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni protein kinase 0.0167 0.0242 0.0612
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0115 0.029
Echinococcus multilocularis serine:threonine protein kinase N2 0.0149 0.0192 0.0192
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.1312 0.3454 0.3481
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0334 0.0711 0.0712
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Echinococcus multilocularis tyrosine protein kinase csk 0.0102 0.006 0.006
Echinococcus multilocularis 0.0463 0.1074 0.1074
Brugia malayi hypothetical protein 0.0102 0.006 0.0057
Brugia malayi Protein kinase domain containing protein 0.0301 0.0618 0.0619
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0273 0.0539 0.054
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus multilocularis casein kinase I delta 0.0273 0.0539 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica cell division protein kinase 2, putative 0.0309 0.0642 0.4887
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0301 0.0618 0.2325
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0194 0.0318 0.0318
Echinococcus multilocularis tyrosine kinase 0.0184 0.029 0.029
Leishmania major protein kinase, putative 0.0167 0.0242 0.0905
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0028 0.0024
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0133 0.0147 0.0309
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1024 0.2647 1
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0149 0.0192 0.0189
Onchocerca volvulus 0.0082 0.0004 0.0001
Brugia malayi hypothetical protein 0.0156 0.0211 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni SH2A 0.0082 0.0004 0.0011
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0146 0.0183 0.0463
Echinococcus granulosus casein kinase I delta 0.0273 0.0539 0.1134
Entamoeba histolytica protein kinase, putative 0.0149 0.0192 0.1462
Giardia lamblia Kinase, CMGC GSK 0.0485 0.1135 0.6236
Schistosoma mansoni cell adhesion molecule 0.0133 0.0147 0.0372
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.0904 0.2286
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0623 0.1522 0.1531
Echinococcus granulosus raf serine:threonine protein kinase 0.0152 0.02 0.042
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0121 0.0114 0.0111
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0164 0.0234 0.0876
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Echinococcus granulosus Vam6:Vps39 protein 0.0194 0.0318 0.0668
Echinococcus multilocularis roundabout 2 0.0133 0.0147 0.0147
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0403 0.0904 0.0908
Toxoplasma gondii casein kinase I 0.0273 0.0539 0.4284
Plasmodium falciparum serine/threonine protein kinase, putative 0.0375 0.0826 0.6569
Echinococcus granulosus integrin linked protein kinase 0.0102 0.006 0.0127
Echinococcus multilocularis dual specificity testis specific protein kinase 0.102 0.2636 0.2636
Brugia malayi serine/threonine kinase 12 0.0375 0.0826 0.0829
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0134 0.015 0.015
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0102 0.006 0.046
Leishmania major protein kinase A catalytic subunit 0.0241 0.045 0.1692
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Plasmodium vivax protein kinase, putative 0.0102 0.006 0.0459
Brugia malayi protein unc-22 0.0155 0.021 0.0207
Echinococcus granulosus tyrosine protein kinase 0.0102 0.006 0.0127
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0779 0.1958 0.1971
Entamoeba histolytica SH2 domain containing protein 0.0082 0.0004 0.0034
Echinococcus multilocularis NCK adaptor protein 0.0153 0.0203 0.0203
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Echinococcus multilocularis tyrosine protein kinase csk 0.0102 0.006 0.006
Echinococcus multilocularis mitogen activated protein kinase 14 0.1024 0.2647 0.2647
Echinococcus granulosus Protein kinase C brain isozyme 0.0199 0.0331 0.0696
Echinococcus granulosus tyrosine protein kinase csk 0.0102 0.006 0.0127
Brugia malayi Sex muscle abnormal protein 5 0.0146 0.0183 0.018
Loa Loa (eye worm) RGC/RGC protein kinase 0.0102 0.006 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica cell division protein kinase 2, putative 0.0301 0.0618 0.4698
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0409 0.092 0.092
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0779 0.1958 0.1971
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0082 0.0004 0.0009
Brugia malayi Protein kinase domain containing protein 0.0184 0.029 0.0288
Entamoeba histolytica protein kinase, putative 0.0375 0.0826 0.6281
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0573 0.1381 0.1389
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0273 0.0539 0.054
Schistosoma mansoni tyrosine kinase 0.0184 0.029 0.0734
Echinococcus multilocularis cyclin dependent kinase 19 0.0929 0.238 0.238
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.021 0.0207
Plasmodium falciparum calcium-dependent protein kinase 4 0.0205 0.0351 0.2776
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0132 0.0144 0.014
Plasmodium falciparum tyrosine kinase-like protein 0.0102 0.006 0.0459
Echinococcus granulosus c src tyrosine kinase 0.0248 0.0469 0.0986
Echinococcus multilocularis activated cdc42 kinase 1 0.0831 0.2105 0.2105
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Echinococcus multilocularis mitogen activated protein kinase 14 0.1024 0.2647 0.2647
Brugia malayi Immunoglobulin I-set domain containing protein 0.0616 0.1502 0.1511
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0103 0.0065 0.0491
Onchocerca volvulus 0.0208 0.0358 0.0357
Entamoeba histolytica protein kinase, putative 0.0205 0.0351 0.2667
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0102 0.006 0.006
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Schistosoma mansoni tyrosine kinase 0.0248 0.0469 0.1185
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Echinococcus multilocularis N chimaerin 0.0132 0.0144 0.0144
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0082 0.0004 0.0004
Giardia lamblia Kinase, CMGC CDK 0.0301 0.0618 0.3233
Schistosoma mansoni myosin-binding protein-related 0.009 0.0028 0.0072
Brugia malayi Protein kinase domain containing protein 0.0149 0.0192 0.0189
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0528 0.1255 0.1262
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0133 0.0147 0.0147
Loa Loa (eye worm) TK protein kinase 0.0263 0.0512 0.0512
Echinococcus granulosus slit 2 protein 0.0126 0.0128 0.0268
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0102 0.006 0.0057
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0102 0.006 0.0323
Brugia malayi Variant SH3 domain containing protein 0.0146 0.0183 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.1314 0.3322
Brugia malayi Protein kinase domain containing protein 0.0184 0.029 0.0288
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Echinococcus granulosus aurora kinase A 0.0375 0.0826 0.1735
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.009 0.0028 0.0024
Toxoplasma gondii aurora kinase 0.0375 0.0826 0.6569
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.1255 0.3173
Echinococcus multilocularis PAK box P21 Rho binding 0.0134 0.015 0.015
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0241 0.045 0.1692
Onchocerca volvulus 0.0102 0.006 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) TK/FER protein kinase 0.0184 0.029 0.0288
Entamoeba histolytica protein kinase, putative 0.0165 0.0239 0.1816
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0167 0.0242 0.0905
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0205 0.0351 0.0349
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0331 0.0837
Echinococcus multilocularis casein kinase i 0.0273 0.0539 0.0539
Brugia malayi hypothetical protein 0.0279 0.0556 0.0556
Leishmania major hypothetical protein, conserved 0.0102 0.006 0.0218
Echinococcus granulosus suppressor of cytokine signaling 6 0.0082 0.0004 0.0009
Brugia malayi Tyrosine-protein kinase PR2 0.0102 0.006 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0241 0.045 0.1692
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0028 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni tyrosine kinase 0.0531 0.1263 0.3193
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0485 0.1135 0.9042
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Brugia malayi bone morphogenetic protein type 1 receptor 0.0417 0.0945 0.0949
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0102 0.006 0.0323
Entamoeba histolytica protein kinase, putative 0.0134 0.015 0.1138
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0164 0.0234 0.0234
Trypanosoma brucei casein kinase I, isoform 2 0.0273 0.0539 0.2029
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0259 0.05 0.05
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni thyroid hormone receptor 0.0151 0.0198 0.0501
Loa Loa (eye worm) hypothetical protein 0.0121 0.0114 0.011
Echinococcus granulosus protein kinase C gamma type 0.0149 0.0192 0.0404
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.006 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0121 0.0114 0.011
Brugia malayi Protein kinase domain containing protein 0.0779 0.1958 0.1971
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Onchocerca volvulus 0.0102 0.006 0.0057
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.098 0.2522 0.2522
Schistosoma mansoni signal transduction protein lnk-related 0.0082 0.0004 0.0011
Echinococcus multilocularis roundabout 2 0.0133 0.0147 0.0147
Entamoeba histolytica hypothetical protein 0.0081 0.0003 0.0022
Loa Loa (eye worm) TK/FAK protein kinase 0.1508 0.4003 0.4034
Trichomonas vaginalis STE family protein kinase 0.0717 0.1784 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0473 0.1102 0.2316
Loa Loa (eye worm) hypothetical protein 0.0269 0.0529 0.0529
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0383 0.0848 0.1782
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.045
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0693 0.1718 0.1718
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0205 0.0351 0.2776
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0133 0.0147 0.0372
Schistosoma mansoni septate junction protein 0.0121 0.0114 0.0288
Schistosoma mansoni protein kinase 0.0134 0.015 0.0378
Echinococcus granulosus signal transduction protein lnk realted 0.0082 0.0004 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.147 0.3897 0.3928
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0549 0.1314 0.496
Echinococcus granulosus epidermal growth factor receptor 0.0295 0.0602 0.1266
Onchocerca volvulus 0.0102 0.006 0.0057
Echinococcus granulosus tyrosine kinase 0.0345 0.0742 0.1559
Entamoeba histolytica hypothetical protein 0.0081 0.0003 0.0022
Schistosoma mansoni hypothetical protein 0.0082 0.0004 0.0011
Schistosoma mansoni protein kinase 0.0693 0.1718 0.4343
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus multilocularis beta adrenergic receptor kinase 0.0121 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0121 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0121 0.0114 0.011
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0241 0.045 0.045
Echinococcus multilocularis activin receptor type 0.1777 0.4758 0.4758
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0409 0.092 0.092
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0205 0.0351 0.0351
Onchocerca volvulus 0.0297 0.0608 0.061
Schistosoma mansoni vav2 0.0148 0.019 0.0481
Entamoeba histolytica serine/threonine kinase, putative 0.0102 0.006 0.046
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0176 0.0269 0.0269
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0082 0.0004 0.0004
Loa Loa (eye worm) TK/ABL protein kinase 0.0865 0.22 0.2216
Loa Loa (eye worm) TK/INSR protein kinase 0.0531 0.1263 0.127
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0205 0.0351 0.2776
Echinococcus multilocularis serine:threonine protein kinase 38 0.0149 0.0192 0.0192
Entamoeba histolytica protein kinase, putative 0.0205 0.0351 0.2667
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Echinococcus granulosus hypothetical protein 0.0463 0.1074 0.2257
Schistosoma mansoni tyrosine kinase 0.0102 0.006 0.0153
Echinococcus granulosus rho-associated protein kinase 1 0.0707 0.1756 0.369
Schistosoma mansoni tyrosine kinase 0.0923 0.2363 0.5973
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0329 0.0697 0.0698
Brugia malayi SH2 domain containing protein 0.0184 0.029 0.0288
Trichomonas vaginalis TK family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0248 0.0469 0.1185
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Loa Loa (eye worm) TK/DDR protein kinase 0.0102 0.006 0.0057
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0149 0.0192 0.0192
Echinococcus granulosus fibroblast growth factor receptor 4 0.0537 0.1281 0.2693
Entamoeba histolytica PH domain containing protein kinase, putative 0.0081 0.0003 0.0022
Loa Loa (eye worm) TK/KIN16 protein kinase 0.147 0.3897 0.3928
Toxoplasma gondii STE kinase 0.0102 0.006 0.0459
Trichomonas vaginalis STE family protein kinase 0.0134 0.015 0.0823
Echinococcus granulosus twitchin 0.041 0.0925 0.1943
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0051 0.0047
Schistosoma mansoni tyrosine kinase 0.0783 0.1971 0.4981
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0192 0.1062
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0099 0.0051 0.0047
Echinococcus granulosus protein kinase c epsilon type 0.0199 0.0331 0.0696
Brugia malayi cyclin-dependent kinase 9 0.0115 0.0098 0.0094
Giardia lamblia Kinase, CMGC GSK 0.0485 0.1135 0.6236
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Brugia malayi Protein kinase domain containing protein 0.0549 0.1314 0.1322
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0102 0.006 0.0127
Loa Loa (eye worm) plexin A 0.0125 0.0125 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Trypanosoma cruzi casein kinase, putative 0.0273 0.0539 0.2029
Entamoeba histolytica protein kinase, putative 0.0103 0.0065 0.0491
Echinococcus multilocularis raf serine:threonine protein kinase 0.0152 0.02 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0485 0.1135 0.6358
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0573 0.1381 0.1381
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1024 0.2647 1
Brugia malayi Fibronectin type III domain containing protein 0.0279 0.0556 0.0556
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Entamoeba histolytica serine/threonine protein kinase, putative 0.0164 0.0234 0.1784
Leishmania major protein kinase, putative 0.0102 0.006 0.0218
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0109 0.008 0.0168
Echinococcus granulosus tyrosine protein kinase pr2 0.0102 0.006 0.0127
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0102 0.006 0.006
Brugia malayi protein C17H12.11 0.0269 0.0529 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.006 0.0323
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0155 0.021 0.0207
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Onchocerca volvulus 0.009 0.0028 0.0025
Brugia malayi Raf kinase 0.0102 0.006 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0375 0.0826 0.4619
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0871 0.2216 0.2232
Echinococcus multilocularis hemicentin 1 0.0121 0.0114 0.0114
Loa Loa (eye worm) CAMK protein kinase 0.0155 0.021 0.0207
Echinococcus granulosus tyrosine protein kinase csk 0.0102 0.006 0.0127
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0587 0.1422 0.1422
Loa Loa (eye worm) hypothetical protein 0.0446 0.1025 0.103
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Brugia malayi intracellular kinase 0.0485 0.1135 0.1141
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0082 0.0004 0.0009
Brugia malayi cell division control protein 2 homolog 0.0301 0.0618 0.0619
Schistosoma mansoni tyrosine kinase 0.0295 0.0602 0.1522
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0432 0.1093
Echinococcus multilocularis cyclin dependent kinase 5 0.0301 0.0618 0.0618
Loa Loa (eye worm) serine/threonine protein kinase 0.0102 0.006 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0082 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0097 0.0046 0.0042
Trichomonas vaginalis CK1 family protein kinase 0.0273 0.0539 0.3013
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Schistosoma mansoni cell adhesion molecule 0.0121 0.0114 0.0288
Echinococcus multilocularis thyroid hormone receptor alpha 0.0151 0.0198 0.0198
Schistosoma mansoni titin 0.0155 0.021 0.0531
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0331 0.0837
Loa Loa (eye worm) TK/ALK protein kinase 0.2312 0.6257 0.631
Schistosoma mansoni tyrosine kinase 0.0193 0.0317 0.08
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Leishmania major protein kinase, putative 0.0375 0.0826 0.3111
Echinococcus granulosus mitogen activated protein kinase 11 0.1024 0.2647 0.5564
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.1422 0.3594
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0518 0.1228 0.1228
Brugia malayi Serine/threonine-protein kinase SULU 0.1312 0.3454 0.3481
Echinococcus multilocularis tyrosine protein kinase HCK 0.0263 0.0512 0.0512
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0098 0.0743
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) TK/ACK protein kinase 0.0102 0.006 0.0057
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0102 0.006 0.0057
Schistosoma mansoni hypothetical protein 0.0156 0.0211 0.0533
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0485 0.1135 0.1141
Brugia malayi Protein kinase domain containing protein 0.0165 0.0239 0.0236
Brugia malayi Receptor family ligand binding region containing protein 0.0102 0.006 0.0057
Schistosoma mansoni neuroglian 0.0133 0.0147 0.0372
Trypanosoma cruzi protein kinase, putative 0.0102 0.006 0.0218
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0717 0.1784 0.1796
Entamoeba histolytica tyrosin kinase, putative 0.0102 0.006 0.046
Trichomonas vaginalis STE family protein kinase 0.0102 0.006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0269 0.0529 0.0529
Onchocerca volvulus 0.0102 0.006 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0528 0.1255 0.7032
Schistosoma mansoni protein kinase 0.0134 0.015 0.0378
Loa Loa (eye worm) TK protein kinase 0.0345 0.0742 0.0744
Loa Loa (eye worm) gastrulation defective protein 1 0.0864 0.2198 0.2214
Brugia malayi Tyrosine-protein kinase abl-1 0.0508 0.1199 0.1206
Loa Loa (eye worm) hypothetical protein 0.0164 0.0234 0.0232
Schistosoma mansoni protein kinase 0.0717 0.1784 0.4509
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0121 0.0114 0.0288
Brugia malayi Protein kinase domain containing protein 0.0334 0.0711 0.0712
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0164 0.0234 0.0876
Echinococcus multilocularis tyrosine protein kinase Blk 0.0345 0.0742 0.0742
Brugia malayi hypothetical protein 0.0269 0.0529 0.0529
Giardia lamblia Kinase, AGC PKA 0.0241 0.045 0.2263
Echinococcus multilocularis casein kinase I alpha 0.0273 0.0539 0.0539
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0194 0.0318 0.0803
Schistosoma mansoni nck2/grb4 0.0146 0.0183 0.0463
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0301 0.0618 0.4908
Echinococcus multilocularis natriuretic peptide receptor 1 0.0102 0.006 0.006
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0146 0.0183 0.018
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0587 0.1422 0.143
Brugia malayi EGF-like domain containing protein 0.0126 0.0128 0.0124
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0102 0.006 0.0153
Schistosoma mansoni protein kinase 0.0102 0.006 0.0153
Loa Loa (eye worm) RGC/RGC protein kinase 0.0102 0.006 0.0057
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0102 0.006 0.046
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0375 0.0826 0.1735
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0234 0.0593
Loa Loa (eye worm) hypothetical protein 0.0146 0.0183 0.018
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0488 0.1142 0.1148
Toxoplasma gondii AGC kinase 0.0241 0.045 0.3573
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Brugia malayi Protein kinase domain containing protein 0.0102 0.006 0.0057
Echinococcus multilocularis insulin receptor 0.0531 0.1263 0.1263
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0102 0.006 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Echinococcus granulosus SH2 domain containing adapter protein F 0.0082 0.0004 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Onchocerca volvulus Tyrosine kinase homolog 0.124 0.3251 0.3276
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Echinococcus granulosus tyrosine protein kinase shark 0.0184 0.029 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0102 0.006 0.046
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0028 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0929 0.238 0.6016
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0301 0.0618 0.0619
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0383 0.085 0.0853
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0301 0.0618 0.1298
Plasmodium falciparum protein serine/threonine kinase-1 0.0528 0.1255 1
Schistosoma mansoni vesicular amine transporter 0.0267 0.0522 0.1321
Loa Loa (eye worm) hypothetical protein 0.0099 0.0053 0.0049
Brugia malayi Protein kinase domain containing protein 0.2313 0.626 0.6312
Brugia malayi putative serine/threonine kinase SADA gamma 0.0164 0.0234 0.0232
Trichomonas vaginalis CMGC family protein kinase 0.0301 0.0618 0.3451
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0146 0.0183 0.018
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Onchocerca volvulus 0.014 0.0166 0.0164
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.006 0.046
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0239 0.1324
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Loa Loa (eye worm) TK protein kinase 0.0102 0.006 0.0057
Onchocerca volvulus 0.0335 0.0714 0.0717
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0205 0.0351 0.0737
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Schistosoma mansoni adapter molecule crk 0.0146 0.0183 0.0463
Echinococcus multilocularis epidermal growth factor receptor 0.0295 0.0602 0.0602
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0121 0.0115 0.0111
Entamoeba histolytica receptor protein kinase, putative 0.0102 0.006 0.046
Onchocerca volvulus 0.009 0.0028 0.0025
Trichomonas vaginalis TKL family protein kinase 0.0102 0.006 0.0323
Trypanosoma cruzi protein kinase, putative 0.0102 0.006 0.0218
Trypanosoma brucei rac serine-threonine kinase, putative 0.0165 0.0239 0.0892
Plasmodium falciparum tyrosine kinase-like protein 0.0102 0.006 0.0459
Schistosoma mansoni tensin-related 0.0082 0.0004 0.0011
Entamoeba histolytica protein kinase, putative 0.0102 0.006 0.046
Loa Loa (eye worm) hypothetical protein 0.0102 0.006 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0234 0.13
Entamoeba histolytica serine/threonine kinase, putative 0.0102 0.006 0.046
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0133 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0362 0.0791 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0234 0.0593
Echinococcus multilocularis protein kinase c iota type 0.0199 0.0331 0.0331
Echinococcus multilocularis aurora kinase A 0.0375 0.0826 0.0826
Brugia malayi Prion-like- 0.0121 0.0114 0.011
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0241 0.045 0.1692
Brugia malayi serine/threonine-protein kinase 6 0.0375 0.0826 0.0829

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 100 um PUBCHEM_BIOASSAY: TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70. (Class of assay: confirmatory) [Related pubchem assays: 583 ] ChEMBL. No reference
IC50 (binding) > 100 um PUBCHEM_BIOASSAY: High Throughput Screening Assay for Hsp70 Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 786 ] ChEMBL. No reference
IC50 (binding) = 999 um PUBCHEM_BIOASSAY: High Throughput Screening Assay for Hsc70 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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