Detailed information for compound 1476088

Basic information

Technical information
  • TDR Targets ID: 1476088
  • Name: (2R)-2-(6-methoxynaphthalen-2-yl)propanoic ac id
  • MW: 230.259 | Formula: C14H14O3
  • H donors: 1 H acceptors: 2 LogP: 3.18 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)ccc(c2)[C@H](C(=O)O)C
  • InChi: 1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m1/s1
  • InChiKey: CMWTZPSULFXXJA-SECBINFHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-2-(6-methoxy-2-naphthyl)propanoic acid
  • (2R)-2-(6-methoxy-2-naphthyl)propionic acid
  • (R)-(−)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
  • 570842_ALDRICH
  • Prestwick2_000045
  • BSPBio_000922
  • SPBio_002090
  • Prestwick1_000045
  • Prestwick3_000791
  • BPBio1_001016
  • Prestwick0_000045

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis chromobox protein 1 0.0084 0.0076 0.0075
Brugia malayi chromobox protein homolog 3 0.0047 0.0033 0.0031
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.0132 0.1679
Onchocerca volvulus Huntingtin homolog 0.0121 0.012 0.0117
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0015 0.1772
Brugia malayi PAS domain containing protein 0.0096 0.0091 0.0089
Schistosoma mansoni laminin gamma-3 chain 0.0031 0.0013 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Onchocerca volvulus Prolyl endopeptidase homolog 0.0669 0.0771 0.0769
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0033 0.0422
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0028 0.0365
Echinococcus granulosus protein jagged 1 0.0031 0.0013 0.0012
Echinococcus multilocularis hormone sensitive lipase 0.0253 0.0277 0.0276
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.001 0.0027
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0253 0.0277 0.0276
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0008 0.0007
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0153 0.0152
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Schistosoma mansoni chromobox protein 0.0084 0.0076 0.0075
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0015 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0106 0.1371
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Schistosoma mansoni intermediate filament proteins 0.0054 0.0041 0.004
Schistosoma mansoni bromodomain containing protein 0.008 0.0071 0.007
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0184 0.0195 0.0194
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0034 0.0017 0.0016
Brugia malayi Serine protease Z688.6 precursor 0.0022 0.0003 0.0001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0146 0.0145
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0409 0.0462 0.0461
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0037 0.0477
Echinococcus multilocularis chromobox protein 1 0.0084 0.0076 0.0075
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0008 0.0066
Loa Loa (eye worm) hypothetical protein 0.0047 0.0032 0.0031
Loa Loa (eye worm) notch protein 0.0031 0.0013 0.0012
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0019 0.2039
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0281 0.031 0.3995
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.01 0.0296
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.003
Mycobacterium tuberculosis Probable oxidoreductase 0.0236 0.0257 0.3297
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0015 0.0175
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0005 0.0003
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0005 0.0004
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0669 0.0771 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0003
Echinococcus multilocularis 0.0056 0.0043 0.0042
Onchocerca volvulus 0.0024 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0008 0.0107
Brugia malayi CXXC zinc finger family protein 0.0057 0.0044 0.0043
Onchocerca volvulus 0.0057 0.0044 0.0042
Toxoplasma gondii thioredoxin reductase 0.0093 0.0087 0.0256
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 0.0973
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0013 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0032 0.0031
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.034 0.038 0.0379
Onchocerca volvulus 0.0031 0.0013 0.001
Schistosoma mansoni cpg binding protein 0.0057 0.0044 0.0043
Echinococcus granulosus lamin dm0 0.0054 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Echinococcus multilocularis epidermal growth factor receptor 0.0097 0.0091 0.009
Onchocerca volvulus Huntingtin homolog 0.0121 0.012 0.0117
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0004 0.0006
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.01 0.0099
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0097 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0119 0.0117 0.0116
Echinococcus granulosus voltage gated potassium channel 0.0034 0.0017 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0028 0.0365
Loa Loa (eye worm) glutathione reductase 0.0093 0.0087 0.0086
Giardia lamblia Alanyl dipeptidyl peptidase 0.0669 0.0771 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Onchocerca volvulus Slit protein homolog 0.0031 0.0013 0.001
Schistosoma mansoni notch 0.0031 0.0013 0.0012
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0006 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.01 0.0099
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Trypanosoma cruzi prolyl endopeptidase 0.0669 0.0771 0.2301
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0669 0.0771 0.2301
Echinococcus multilocularis musashi 0.0054 0.0041 0.004
Brugia malayi hypothetical protein 0.0286 0.0316 0.0314
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0015 0.0147
Entamoeba histolytica prolyl oligopeptidase family protein 0.0669 0.0771 1
Echinococcus granulosus geminin 0.034 0.038 0.0379
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0109 0.0106 0.0312
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0036 0.039
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0006 0.0014
Echinococcus granulosus hormone sensitive lipase 0.0253 0.0277 0.0276
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0139 0.0138
Loa Loa (eye worm) hypothetical protein 0.0121 0.012 0.0118
Loa Loa (eye worm) hypothetical protein 0.0085 0.0078 0.0077
Schistosoma mansoni hypothetical protein 0.0047 0.0032 0.0031
Echinococcus multilocularis epidermal growth factor receptor 0.018 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 0.0857
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0108 0.1403
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0032 0.0031
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0015 0.0013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0028 0.0027
Echinococcus granulosus lamin 0.0054 0.0041 0.004
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0006 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0025 0.032
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0004 0.0003
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0004 0.0008
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 0.0831
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0015 0.004
Brugia malayi GCC2 and GCC3 family protein 0.0031 0.0013 0.0012
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0023 0.0004 0.0003
Schistosoma mansoni lipoxygenase 0.01 0.0095 0.0094
Brugia malayi Delta serrate ligand family protein 0.0031 0.0013 0.0012
Brugia malayi MAP kinase sur-1 0.0104 0.01 0.0099
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0119 0.0117 0.0116
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0004 0.0057
Echinococcus multilocularis prolyl endopeptidase 0.0669 0.0771 0.077
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0006 0.0005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0006 0.008
Toxoplasma gondii ABC1 family protein 0.0043 0.0028 0.008
Plasmodium vivax hypothetical protein, conserved 0.0669 0.0771 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0028 0.008
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0015 0.0152
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0004 0.0003
Treponema pallidum fructose-bisphosphate aldolase 0.0575 0.0659 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0109 0.0106 0.1356
Echinococcus multilocularis fatty acid binding protein FABP2 0.0042 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.008
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0281 0.031 0.3974
Loa Loa (eye worm) phosphofructokinase 0.0131 0.0132 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0669 0.0771 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0067 0.0066
Schistosoma mansoni notch 0.0031 0.0013 0.0012
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0106 0.1371
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0022 0.0003 0.0002
Trichomonas vaginalis sucrase-isomaltase, putative 0.0109 0.0106 0.1371
Echinococcus multilocularis neurogenic locus protein delta 0.0031 0.0013 0.0012
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0015 0.004
Onchocerca volvulus Peroxidase homolog 0.0286 0.0316 0.0313
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0005 0.0004
Leishmania major importin beta-1 subunit, putative 0.0023 0.0004 0.0008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0028 0.0321
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0669 0.0771 0.2301
Brugia malayi Thioredoxin reductase 0.0093 0.0087 0.0086
Mycobacterium tuberculosis Conserved protein 0.0043 0.0028 0.0321
Onchocerca volvulus 0.0286 0.0316 0.0313
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.002 0.0255
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0109 0.0106 0.1371
Echinococcus multilocularis peroxidasin 0.0286 0.0316 0.0315
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0005 0.0003
Brugia malayi prolyl oligopeptidase family protein 0.0669 0.0771 0.077
Leishmania major hypothetical protein, conserved 0.0043 0.0028 0.008
Echinococcus multilocularis slit 2 protein 0.0031 0.0013 0.0012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0004 0.0028
Brugia malayi intermediate filament protein 0.0054 0.0041 0.004
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0017 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0002 0.0001
Mycobacterium ulcerans hypothetical protein 0.0043 0.0028 0.0321
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.01 0.0099
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0005 0.0004
Onchocerca volvulus 0.0284 0.0313 0.0311
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0031 0.0013 0.0012
Schistosoma mansoni zinc finger protein 0.0027 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0054 0.0041 0.004
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0019 0.0225
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0004 0.0003
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0032 0.0031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0004 0.005
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.2838 0.3347 1
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0011 0.001
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0015 0.0175
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 1
Echinococcus granulosus single minded 2 0.0082 0.0074 0.0073
Brugia malayi Animal haem peroxidase family protein 0.0286 0.0316 0.0314
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0005 0.0003
Treponema pallidum NADH oxidase 0.0032 0.0015 0.0172
Schistosoma mansoni cpg binding protein 0.0063 0.0051 0.005
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0132 0.1703
Echinococcus granulosus epidermal growth factor receptor 0.0097 0.0091 0.009
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0067 0.0197
Schistosoma mansoni hypothetical protein 0.0047 0.0032 0.0031
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0025 0.032
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0281 0.031 0.3995
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0007 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.0195 0.249
Brugia malayi Glycosyl hydrolases family 31 protein 0.0109 0.0106 0.0104
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0067 0.0857
Schistosoma mansoni slit 0.0031 0.0013 0.0012
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0058 0.0045 0.0044
Trypanosoma cruzi trypanothione reductase, putative 0.0093 0.0087 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0067 0.0066
Schistosoma mansoni polycystin 1-related 0.0024 0.0005 0.0004
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0669 0.0771 1
Onchocerca volvulus 0.0024 0.0005 0.0002
Echinococcus granulosus delta-like protein 1 0.0031 0.0013 0.0012
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0015 0.0192
Schistosoma mansoni tyrosine kinase 0.0096 0.009 0.0089
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0019 0.2039
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0022 0.0003 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0108 0.0319
Toxoplasma gondii EGF family domain-containing protein 0.0031 0.0013 0.0035
Brugia malayi hypothetical protein 0.2169 0.2552 0.2551
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0019
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0004 0.0003
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0015 0.1412
Echinococcus granulosus snurportin 1 0.0303 0.0336 0.0335
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0139 0.0138
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0028 0.008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0139 0.0138
Onchocerca volvulus Dual oxidase homolog 0.0286 0.0316 0.0313
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0023 0.0004 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0015 0.0175
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0004 0.0003
Brugia malayi 6-phosphofructokinase 0.0131 0.0132 0.0131
Schistosoma mansoni tyrosine kinase 0.0096 0.009 0.0089
Echinococcus multilocularis neutral alpha glucosidase AB 0.0109 0.0106 0.0105
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0669 0.0771 0.2301
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.01 0.13
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0669 0.0771 1
Leishmania major oligopeptidase b 0.0669 0.0771 0.2301
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0004 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.01 0.13
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0007 0.0018
Echinococcus multilocularis neural cadherin 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0669 0.0771 0.077
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.8442 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0139 0.0138
Leishmania major glycosyl hydrolase-like protein 0.0041 0.0025 0.007
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0019 0.0225
Trichomonas vaginalis chaperonin, putative 0.0024 0.0005 0.0063
Mycobacterium tuberculosis Conserved protein 0.0043 0.0028 0.0321
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0028 0.0027
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0034 0.0017 0.0016
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0409 0.0462 0.0461
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0031
Brugia malayi Inositol-1 0.0036 0.002 0.0018
Onchocerca volvulus 0.0054 0.0041 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0015 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.049 0.0559 0.0557
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0067 0.0066
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.0132 0.165
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0005 0.0003
Loa Loa (eye worm) thioredoxin reductase 0.0093 0.0087 0.0086
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0139 0.0138
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0409 0.0462 0.0461
Brugia malayi notch-like transmembrane receptor 0.0031 0.0013 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0028 0.0349
Giardia lamblia Thymus-specific serine protease precursor 0.0022 0.0003 0.0017
Schistosoma mansoni tyrosine kinase 0.0058 0.0045 0.0044
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0005 0.0004
Onchocerca volvulus 0.0043 0.0028 0.0026
Echinococcus granulosus chromobox protein 1 0.0084 0.0076 0.0075
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0028 0.0321
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.0025 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0007 0.0018
Schistosoma mansoni fatty acid binding protein 0.0042 0.0026 0.0025
Onchocerca volvulus Peroxidasin homolog 0.0286 0.0316 0.0313
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0008 0.0007
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0005 0.0045
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.2838 0.3347 1
Echinococcus granulosus chromobox protein 1 0.0084 0.0076 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0033 0.0422
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0669 0.0771 0.077
Brugia malayi Cyclic-nucleotide gated cation channel 0.0023 0.0004 0.0003
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0019 0.0231
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0132 0.0392
Echinococcus granulosus lysosomal alpha glucosidase 0.049 0.0559 0.0558
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0019 0.0052
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0006 0.008
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0037 0.0477
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0067 0.0066
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0031 0.0013 0.0012
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.6597 0.7809 0.7809
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0019 0.0242
Trypanosoma brucei trypanothione reductase 0.0093 0.0087 0.0256
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0212 0.0228 0.2931
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.01 0.0296
Onchocerca volvulus Putative cubilin 0.0031 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.002 0.0055
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0669 0.0771 0.077
Schistosoma mansoni loxhd1 0.0024 0.0005 0.0004
Trypanosoma brucei protein kinase, putative 0.0104 0.01 0.0296
Echinococcus multilocularis fatty acid binding protein FABP2 0.0042 0.0026 0.0025
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Schistosoma mansoni ap endonuclease 0.0023 0.0004 0.0003
Brugia malayi Muscle positioning protein 4 0.0031 0.0013 0.0012
Echinococcus multilocularis neurogenic locus notch protein 4 0.0031 0.0013 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0139 0.0138
Schistosoma mansoni tyrosine kinase 0.018 0.019 0.0189
Echinococcus multilocularis GPCR, family 2 0.0047 0.0032 0.0031
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.002 0.2532
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Brugia malayi Calcium binding EGF domain containing protein 0.0031 0.0013 0.0012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0028 0.0027
Onchocerca volvulus 0.0031 0.0013 0.001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0015 0.0014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0236 0.0257 0.3297
Echinococcus granulosus protein jagged 2 0.0031 0.0013 0.0012
Mycobacterium tuberculosis Probable peptidase 0.0669 0.0771 1
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0067 0.0066
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0153 0.0152
Loa Loa (eye worm) hypothetical protein 0.0669 0.0771 0.077
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0669 0.0771 1
Onchocerca volvulus 0.0031 0.0013 0.001
Loa Loa (eye worm) blistered cuticle protein 3 0.0286 0.0316 0.0314
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0001 0.0015
Echinococcus multilocularis notch 0.0031 0.0013 0.0012
Echinococcus granulosus neurogenic locus protein delta 0.0031 0.0013 0.0012
Echinococcus multilocularis geminin 0.034 0.038 0.0379
Plasmodium vivax importin-beta 2, putative 0.0028 0.001 0.0116
Brugia malayi beta-lactamase 0.0043 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0001
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0005 0.0004
Brugia malayi Bromodomain containing protein 0.0094 0.0088 0.0087
Onchocerca volvulus Chorion peroxidase homolog 0.0286 0.0316 0.0313
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Plasmodium falciparum peptidase, putative 0.0669 0.0771 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0028 0.0321
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0119 0.0117 0.0116
Plasmodium falciparum thioredoxin reductase 0.0032 0.0015 0.0175
Echinococcus multilocularis neurogenic locus notch protein 0.0031 0.0013 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0132 0.1717
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0119 0.0117 0.0116
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0076 0.0991
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0121 0.0119
Schistosoma mansoni alpha-glucosidase 0.0422 0.0478 0.0477
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0008 0.0084
Echinococcus granulosus neuropeptide s receptor 0.137 0.1603 0.1602
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0212 0.0228 0.2931
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0004 0.005
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0067 0.0066
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0028 0.0027
Loa Loa (eye worm) TK/EGFR protein kinase 0.018 0.019 0.0189
Schistosoma mansoni hypothetical protein 0.0047 0.0032 0.0031
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.002 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0019 0.0242
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0005 0.001
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0022 0.0003 0.0017
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0184 0.0195 0.0578
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0008 0.0107
Onchocerca volvulus 0.0025 0.0006 0.0004
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0006 0.0005
Echinococcus granulosus intermediate filament protein 0.0054 0.0041 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0121 0.012 0.0118
Mycobacterium ulcerans beta-lactamase 0.0043 0.0028 0.0321
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0022 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0028 0.008
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0184 0.0195 0.249
Echinococcus granulosus epidermal growth factor receptor 0.018 0.019 0.0189
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0015 0.004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0004 0.0003
Leishmania major trypanothione reductase 0.0093 0.0087 0.0256
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.2169 0.2552 0.2551
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0041 0.0025 0.0022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0004 0.0057
Onchocerca volvulus 0.0043 0.0028 0.0026
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0061 0.0748
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0066 0.0065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0037 0.0034
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0139 0.0138
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0028 0.0321
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0042 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0383 0.0431 0.043
Toxoplasma gondii aldehyde dehydrogenase 0.0184 0.0195 0.0578
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0019 0.0225
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0006 0.008
Schistosoma mansoni notch 0.0031 0.0013 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0005 0.0004
Onchocerca volvulus Neurogenic locus notch homolog 0.0031 0.0013 0.001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0044 0.0043
Echinococcus multilocularis lamin dm0 0.0054 0.0041 0.004
Schistosoma mansoni septate junction protein 0.0031 0.0013 0.0012
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0006 0.0005
Brugia malayi hypothetical protein 0.0322 0.0359 0.0358
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.0025 0.007
Trypanosoma brucei glucosidase, putative 0.0109 0.0106 0.0312
Brugia malayi Animal haem peroxidase family protein 0.0286 0.0316 0.0314
Brugia malayi hypothetical protein 0.0121 0.012 0.0118
Loa Loa (eye worm) animal heme peroxidase 0.0286 0.0316 0.0314
Plasmodium falciparum importin beta, putative 0.0028 0.001 0.0116
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0028 0.0365
Schistosoma mansoni alpha glucosidase 0.0109 0.0106 0.0105
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0015 0.0175
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0139 0.0138
Trypanosoma cruzi oligopeptidase b 0.0669 0.0771 0.2301
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0132 0.0392
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0253 0.0277 0.0276
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0015 0.004
Schistosoma mansoni lamin 0.0054 0.0041 0.004
Echinococcus granulosus peroxidasin 0.0286 0.0316 0.0315
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0153 0.0152
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0022 0.0003 0.0002
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0019 0.0052
Brugia malayi Animal haem peroxidase family protein 0.0286 0.0316 0.0314
Echinococcus multilocularis zinc finger protein 0.0027 0.0008 0.0007
Loa Loa (eye worm) Notch2 0.0031 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0034
Schistosoma mansoni lamin 0.0054 0.0041 0.004
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0132 0.0131
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0015 0.004
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0034 0.0017 0.0016
Entamoeba histolytica hypothetical protein, conserved 0.0669 0.0771 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0004 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0008 0.0107
Brugia malayi RNA, U transporter 1 0.0081 0.0072 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Schistosoma mansoni cell polarity protein 0.0031 0.0013 0.0012
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0019 0.0225
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0028 0.0321
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0106 0.1371
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0004 0.0028
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0097 0.0091 0.009
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0022 0.0003 0.0004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0025 0.0023
Plasmodium falciparum glutathione reductase 0.0032 0.0015 0.0175
Loa Loa (eye worm) hypothetical protein 0.0041 0.0025 0.0023
Brugia malayi TAR-binding protein 0.0076 0.0067 0.0066
Onchocerca volvulus 0.0043 0.0028 0.0026
Echinococcus granulosus protein jagged 2 0.0031 0.0013 0.0012
Brugia malayi hypothetical protein 0.0147 0.0151 0.015
Plasmodium vivax thioredoxin reductase, putative 0.0093 0.0087 0.1113
Echinococcus multilocularis fibropellin Ia 0.0031 0.0013 0.0012
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0004 0.0003
Brugia malayi hypothetical protein 0.0024 0.0005 0.0003
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0022 0.0003 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.01 0.0296
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.0336 0.0335
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0019 0.0242
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0008 0.0107
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Onchocerca volvulus 0.0031 0.0013 0.001
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0006 0.0014
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0004 0.0003
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0005 0.0004
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0055
Brugia malayi Serine carboxypeptidase S28 family protein 0.0022 0.0003 0.0001
Onchocerca volvulus 0.0286 0.0316 0.0313
Schistosoma mansoni notch 0.0031 0.0013 0.0012
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.2838 0.3347 1
Trypanosoma brucei glycosyl hydrolase-like protein 0.0041 0.0025 0.007
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0005 0.0004
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0061 0.006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0015 0.004
Brugia malayi Bromodomain containing protein 0.0046 0.0031 0.003
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0008 0.0084
Echinococcus multilocularis lamin 0.0054 0.0041 0.004
Schistosoma mansoni notch 0.0031 0.0013 0.0012
Brugia malayi phosphofructokinase 0.0131 0.0132 0.0131
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0004 0.0003
Trichomonas vaginalis esterase, putative 0.0043 0.0028 0.0365
Onchocerca volvulus 0.0037 0.002 0.0018
Echinococcus granulosus neurogenic locus notch protein 4 0.0031 0.0013 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0032 0.0031
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0575 0.0659 0.855
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.8442 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0106 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0002 0.0001
Echinococcus multilocularis thioredoxin glutathione reductase 0.0093 0.0087 0.0086
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0025 0.032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0306 0.3946
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.002 0.0019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0025 0.0303
Echinococcus multilocularis insulin receptor 0.0058 0.0045 0.0044
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0212 0.0228 0.2931
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0004 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0067 0.0066
Onchocerca volvulus 0.0054 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0028 0.0027
Loa Loa (eye worm) inositol-1 0.0036 0.002 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0236 0.0257 0.3297
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0016 0.021
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Trypanosoma brucei prolyl oligopeptidase, putative 0.0669 0.0771 0.2301
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0669 0.0771 0.2301
Schistosoma mansoni peroxidasin 0.0286 0.0316 0.0315
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0067 0.0066
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0146 0.0145
Brugia malayi glutathione reductase 0.0093 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0006
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0575 0.0659 0.855
Brugia malayi prolyl oligopeptidase family protein 0.0669 0.0771 0.077
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0008 0.0021
Onchocerca volvulus 0.0031 0.0013 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Onchocerca volvulus 0.0286 0.0316 0.0313
Schistosoma mansoni hypothetical protein 0.0047 0.0032 0.0031
Mycobacterium tuberculosis Probable dehydrogenase 0.0212 0.0228 0.2931
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0005 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0106 0.0312
Schistosoma mansoni tyrosine kinase 0.0097 0.0091 0.009
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0067 0.0066
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0004 0.0003
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0006 0.008
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0669 0.0771 0.077
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.2838 0.3347 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0067 0.0799
Leishmania major alpha glucosidase II subunit, putative 0.0109 0.0106 0.0312
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0004 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Echinococcus granulosus neuropeptide receptor A26 0.137 0.1603 0.1602
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0022 0.0003 0.0034
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0669 0.0771 0.2301
Schistosoma mansoni single-minded 0.0096 0.0091 0.009
Brugia malayi Peroxidasin 0.0286 0.0316 0.0314
Plasmodium falciparum thioredoxin reductase 0.0093 0.0087 0.1113
Echinococcus granulosus neural cadherin 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Echinococcus multilocularis RUN 0.0024 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0025 0.0006 0.0005
Echinococcus granulosus fibropellin Ia 0.0031 0.0013 0.0012
Plasmodium vivax glutathione reductase, putative 0.0093 0.0087 0.1113
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.002 0.0238
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Echinococcus multilocularis snurportin 1 0.0303 0.0336 0.0335
Echinococcus granulosus neutral alpha glucosidase AB 0.0109 0.0106 0.0105
Brugia malayi Cadherin domain containing protein 0.0031 0.0013 0.0012
Mycobacterium tuberculosis Probable reductase 0.0212 0.0228 0.2931
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Leishmania major protein kinase, putative 0.0026 0.0007 0.0018
Brugia malayi Importin beta-1 subunit 0.0028 0.001 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0019 0.0242
Schistosoma mansoni aldehyde dehydrogenase 0.0184 0.0195 0.0194
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0008 0.0107
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.0253 0.0277 0.0276
Schistosoma mansoni tyrosine kinase 0.0097 0.0091 0.009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.0195 0.249
Schistosoma mansoni voltage-gated potassium channel 0.013 0.013 0.0129
Schistosoma mansoni voltage-gated potassium channel 0.013 0.013 0.0129
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0004 0.0045
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0669 0.0771 0.2301
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0013 0.0012
Echinococcus multilocularis acylamino acid releasing enzyme 0.0669 0.0771 0.077
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0015
Echinococcus granulosus neurogenic locus notch protein 0.0031 0.0013 0.0012
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.01 0.0099
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.01 0.0296
Entamoeba histolytica hypothetical protein 0.0023 0.0004 0.0033
Echinococcus multilocularis protein jagged 1 0.0031 0.0013 0.0012
Echinococcus granulosus protein jagged 1 0.0031 0.0013 0.0012
Onchocerca volvulus Peroxidasin homolog 0.0286 0.0316 0.0313
Schistosoma mansoni inositol monophosphatase 0.0036 0.002 0.0019
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0023 0.0004 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0041 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0025 0.032
Brugia malayi Calcium binding EGF domain containing protein 0.0031 0.0013 0.0012
Echinococcus multilocularis importin subunit beta 1 0.0028 0.001 0.0009
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.0005 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.008
Schistosoma mansoni fatty acid binding protein 0.0042 0.0026 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0132 0.1717
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0025 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0034
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Brugia malayi prolyl oligopeptidase family protein 0.2838 0.3347 0.3346
Schistosoma mansoni lipoxygenase 0.0142 0.0146 0.0145
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0028 0.0321
Brugia malayi Heterochromatin protein 1 0.0084 0.0076 0.0075
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0015 0.0147
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0011 0.001
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.0132 0.1965
Loa Loa (eye worm) animal heme peroxidase 0.0286 0.0316 0.0314
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0004 0.0006
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0005 0.0045
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0036 0.0424
Brugia malayi beta-lactamase family protein 0.0043 0.0028 0.0027
Echinococcus multilocularis lysosomal alpha glucosidase 0.049 0.0559 0.0558
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.0132 0.1679
Onchocerca volvulus 0.0071 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0253 0.0277 0.0276
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0106 0.1371
Loa Loa (eye worm) hypothetical protein 0.0669 0.0771 0.077
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0015 0.0147
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0007 0.0018
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0006 0.008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0005
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0669 0.0771 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0066 0.0065
Echinococcus granulosus slit 2 protein 0.0031 0.0013 0.0012
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0006 0.008
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0028 0.0287
Echinococcus multilocularis neurogenic locus notch protein 0.0031 0.0013 0.0012
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0015 0.0117
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0032 0.0031
Echinococcus multilocularis neurogenic locus protein delta 0.0031 0.0013 0.0012
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0669 0.0771 0.2301
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0032 0.0031
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.001 0.0027
Echinococcus granulosus fatty acid binding protein FABP2 0.0042 0.0026 0.0025
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0004 0.0002
Brugia malayi Serine protease Z688.6 precursor 0.0022 0.0003 0.0001
Echinococcus multilocularis protein jagged 1 0.0031 0.0013 0.0012
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0036 0.0424
Trypanosoma brucei prolyl endopeptidase 0.0669 0.0771 0.2301
Schistosoma mansoni chromobox protein 0.0084 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Brugia malayi Probable ClpP-like protease 0.0076 0.0067 0.0066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0006 0.008
Echinococcus granulosus GPCR family 2 0.0047 0.0032 0.0031
Echinococcus multilocularis fat cadherin tumor suppressor 0.0031 0.0013 0.0012
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0013 0.0012
Loa Loa (eye worm) animal heme peroxidase 0.0286 0.0316 0.0314
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0015 0.0147
Brugia malayi Angiotensin-converting enzyme family protein 0.6597 0.7809 0.7809
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0004 0.005
Toxoplasma gondii exonuclease III APE 0.0023 0.0004 0.0006
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.0132 0.0131
Loa Loa (eye worm) prolyl oligopeptidase 0.8442 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0028 0.0365
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0015 0.004
Loa Loa (eye worm) hypothetical protein 0.0076 0.0067 0.0066
Loa Loa (eye worm) RNA binding protein 0.0076 0.0067 0.0066
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0055
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0032 0.0031
Schistosoma mansoni tyrosine kinase 0.0096 0.009 0.0089
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0015 0.004
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0005 0.001
Brugia malayi Protein kinase domain containing protein 0.0058 0.0045 0.0044
Brugia malayi RNA binding protein 0.0076 0.0067 0.0066
Leishmania major protein kinase, putative 0.0042 0.0026 0.0073
Toxoplasma gondii hypothetical protein 0.0669 0.0771 0.2301
Loa Loa (eye worm) hypothetical protein 0.0102 0.0097 0.0096
Schistosoma mansoni hypothetical protein 0.034 0.038 0.0379
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0028 0.0027
Trypanosoma brucei oligopeptidase b 0.0669 0.0771 0.2301
Loa Loa (eye worm) hypoxia-induced factor 1 0.0297 0.033 0.0328
Echinococcus multilocularis neuropeptide receptor A26 0.137 0.1603 0.1602
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.01 0.0099
Echinococcus granulosus neurogenic locus notch protein 0.0031 0.0013 0.0012
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0015 0.0175
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0212 0.0228 0.2931
Brugia malayi prolyl oligopeptidase family protein 0.0669 0.0771 0.077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Giardia lamblia Serine peptidase, putative 0.0022 0.0003 0.0017
Loa Loa (eye worm) TK/INSR protein kinase 0.0058 0.0045 0.0044
Schistosoma mansoni rab6-interacting 0.0024 0.0005 0.0004
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0022 0.0003 0.0034
Echinococcus granulosus cpg binding protein 0.0063 0.0051 0.005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.01 0.0099
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.01 0.0296
Schistosoma mansoni tyrosine kinase 0.0058 0.0045 0.0044
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.001 0.0027
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0006 0.008
Echinococcus granulosus tar DNA binding protein 0.0076 0.0067 0.0066
Echinococcus multilocularis protein jagged 2 0.0031 0.0013 0.0012
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0019 0.0242
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0019 0.0242
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0022 0.0002 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0008 0.0107
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0025 0.032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0008 0.0107
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0019 0.0225
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0055
Brugia malayi 6-phosphofructokinase 0.0131 0.0132 0.0131
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.002 0.0211
Schistosoma mansoni hypothetical protein 0.0024 0.0005 0.0004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0004 0.0003
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.01 0.1285
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0004 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0139 0.0138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0061 0.006
Echinococcus granulosus insulin receptor 0.0058 0.0045 0.0044
Brugia malayi Calcium binding EGF domain containing protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0001
Loa Loa (eye worm) prolyl oligopeptidase 0.0669 0.0771 0.077
Loa Loa (eye worm) hypothetical protein 0.0055 0.0042 0.004
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0005 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0015 0.0192
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0015 0.1772
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0005 0.0045
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.002 0.0255
Schistosoma mansoni peroxidasin 0.0286 0.0316 0.0315
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0022 0.0003 0.0017
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.049 0.0559 0.0557
Brugia malayi Doublecortin family protein 0.0024 0.0005 0.0003
Echinococcus multilocularis lysosomal alpha glucosidase 0.049 0.0559 0.0558
Brugia malayi follicle stimulating hormone receptor 0.0287 0.0317 0.0316
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0669 0.0771 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0035 0.0034
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0076 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0669 0.0771 0.2301
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0034 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0132 0.1717
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0028 0.0321
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0028 0.0365
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0036 0.0035
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.0195 0.249
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.0132 0.0392
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0067 0.0066
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.2838 0.3347 0.3346
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0132 0.0131
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0036 0.0035
Schistosoma mansoni hypothetical protein 0.0102 0.0097 0.0096
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0055
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0031 0.0013 0.001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.01 0.0296
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0002 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0109 0.0106 0.1356
Trypanosoma cruzi hypothetical protein, conserved 0.0669 0.0771 0.2301
Schistosoma mansoni notch 0.0031 0.0013 0.0012
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 0.0831
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.8442 1 1
Echinococcus granulosus notch 0.0031 0.0013 0.0012
Toxoplasma gondii prolyl endopeptidase 0.0669 0.0771 0.2301
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0033 0.003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0028 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0017 0.0016
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0322 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Echinococcus granulosus histone lysine methyltransferase setb 0.0022 0.0002 0.0001
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0067 1
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0067 0.0066
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0093 0.0087 0.1088
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0015 0.004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.01 0.0296
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0106 0.1371
Mycobacterium ulcerans lipase LipD 0.0043 0.0028 0.0321
Schistosoma mansoni rab6-interacting 0.0024 0.0005 0.0004
Brugia malayi hypoxia-induced factor 1 0.0297 0.033 0.0328
Echinococcus granulosus Solute carrier family 22 5 0.25 0.2945 0.2944
Trichomonas vaginalis maltase-glucoamylase, putative 0.0109 0.0106 0.1371
Trypanosoma cruzi oligopeptidase b 0.0669 0.0771 0.2301
Mycobacterium leprae Probable lipase LipE 0.0043 0.0028 0.0287
Echinococcus multilocularis Dipeptidyl peptidase 9 0.2838 0.3347 0.3346
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0025 0.032
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0006 0.0005
Echinococcus granulosus importin subunit beta 1 0.0028 0.001 0.0009
Entamoeba histolytica prolyl oligopeptidase family protein 0.0669 0.0771 1
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0005 0.0003
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0669 0.0771 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0091 0.009
Onchocerca volvulus Peroxidase homolog 0.0286 0.0316 0.0313
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0669 0.0771 0.077
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0108 0.1403
Giardia lamblia High cysteine protein 0.0031 0.0013 0.0153
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0132 0.1717
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0236 0.0257 0.3274
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.012 0.0119
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0022 0.0003 0.0004
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0067 0.0066
Mycobacterium tuberculosis Conserved protein 0.0043 0.0028 0.0321
Brugia malayi Animal haem peroxidase family protein 0.0286 0.0316 0.0314
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0184 0.0195 0.0194
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.002 0.0019
Loa Loa (eye worm) animal heme peroxidase 0.0286 0.0316 0.0314
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0016 0.021
Loa Loa (eye worm) hypothetical protein 0.0103 0.0099 0.0098
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0132 0.0131
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0121 0.0119
Echinococcus granulosus prolyl endopeptidase 0.0669 0.0771 0.077
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.01 0.0296
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0042 0.0026 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.0184 0.0195 0.0194
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0303 0.0336 0.0335
Entamoeba histolytica prolyl oligopeptidase family protein 0.0669 0.0771 1
Brugia malayi Animal haem peroxidase family protein 0.0286 0.0316 0.0314
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0058 0.0045 0.0044
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0076 0.0991
Loa Loa (eye worm) beta-lactamase 0.0043 0.0028 0.0027
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0022 0.0003 0.0034
Schistosoma mansoni alpha-glucosidase 0.0422 0.0478 0.0477
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Echinococcus granulosus Dipeptidyl peptidase 9 0.2838 0.3347 0.3346
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0023 0.0004 0.0003
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.2838 0.3347 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Giardia lamblia Fructose-bisphosphate aldolase 0.0575 0.0659 0.855
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0015 0.004
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0004 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0212 0.0228 0.2906
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0287 0.0317 0.0316
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0022 0.0003 0.0034
Echinococcus granulosus RUN 0.0024 0.0005 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.01 0.13
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0109 0.0106 0.1371
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0015 0.004
Brugia malayi beta-lactamase family protein 0.0043 0.0028 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.137 0.1603 0.1602
Echinococcus multilocularis cpg binding protein 0.0063 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0286 0.0316 0.0314
Schistosoma mansoni cpg binding protein 0.0063 0.0051 0.005
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0132 0.1703
Echinococcus granulosus zinc finger protein 0.0027 0.0008 0.0007
Brugia malayi hypothetical protein 0.0024 0.0005 0.0003
Plasmodium falciparum glutathione reductase 0.0093 0.0087 0.1113
Toxoplasma gondii hypothetical protein 0.0026 0.0008 0.0019
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0041 0.004
Echinococcus multilocularis voltage gated potassium channel 0.0034 0.0017 0.0016
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.8442 1 1
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0005 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0575 0.0659 0.8552
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0028 0.0321
Brugia malayi Furin-like cysteine rich region family protein 0.018 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0039
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0067 0.0197
Giardia lamblia Alanyl dipeptidyl peptidase 0.0669 0.0771 1
Trichomonas vaginalis ran, putative 0.0021 0.0001 0.0017
Schistosoma mansoni ap endonuclease 0.0023 0.0004 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0019 0.0242
Brugia malayi EGF-like domain containing protein 0.0031 0.0013 0.0012
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.2838 0.3347 1
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0132 0.1703
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0005 0.0045
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0006 0.0005
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0109 0.0106 0.0104
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0019 0.0225
Schistosoma mansoni importin beta-1 0.0028 0.001 0.0009
Brugia malayi Cadherin domain containing protein 0.0031 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0012
Echinococcus granulosus acylamino acid releasing enzyme 0.0669 0.0771 0.077
Echinococcus granulosus thioredoxin glutathione reductase 0.0093 0.0087 0.0086
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0005 0.0063
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0025 0.032
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0004 0.0003
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0022 0.0003 0.0004
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0028 0.0321
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0012
Brugia malayi Blistered cuticle protein 3 0.0286 0.0316 0.0314
Brugia malayi PHD-finger family protein 0.0033 0.0016 0.0015
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0132 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.01 0.13
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0008 0.0107
Brugia malayi MH2 domain containing protein 0.0121 0.0121 0.0119
Echinococcus granulosus fatty acid binding protein FABP2 0.0042 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0149 0.0153 0.0152

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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