Detailed information for compound 1491562

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 316.398 | Formula: C17H24N4O2
  • H donors: 1 H acceptors: 3 LogP: 4.51 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCn1c(N)ncc1c1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C17H24N4O2/c1-2-3-4-5-6-7-12-20-16(13-19-17(20)18)14-8-10-15(11-9-14)21(22)23/h8-11,13H,2-7,12H2,1H3,(H2,18,19)
  • InChiKey: WGHIVHKHPMAOGQ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus casein kinase I delta 0.0108 0.0191 0.0191
Onchocerca volvulus 0.014 0.0343 0.1386
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0282 0.1025 0.1025
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0085 0.0082 0.0082
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0086 0.0087 0.0087
Echinococcus granulosus N chimaerin 0.0104 0.0169 0.0169
Giardia lamblia Kinase, CMGC CDK 0.0118 0.024 0.1775
Leishmania major casein kinase, putative 0.0108 0.0191 0.1271
Loa Loa (eye worm) protein kinase domain-containing protein 0.0214 0.0697 0.0691
Brugia malayi Protein kinase domain containing protein 0.0126 0.0277 0.0262
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0222 0.1534
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0186 0.0564 0.0557
Brugia malayi Protein kinase domain containing protein 0.2141 0.9948 1
Echinococcus granulosus c src tyrosine kinase 0.0164 0.0458 0.0458
Brugia malayi Serine/threonine-protein kinase SULU 0.0223 0.074 0.0729
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0082 0.0074
Loa Loa (eye worm) thyroid receptor interactor 0.0114 0.0219 0.0211
Echinococcus granulosus Immunoglobulin 0.0084 0.0075 0.0075
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.2152 1 1
Loa Loa (eye worm) TK protein kinase 0.0286 0.1045 0.1041
Entamoeba histolytica casein kinase, putative 0.01 0.015 0.0943
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0203 0.0645 0.0645
Schistosoma mansoni tyrosine kinase 0.0164 0.0458 0.0452
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0087 0.009 0.0082
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0085 0.0082 0.0072
Brugia malayi protein kinase C II. 0.0211 0.0686 0.0674
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Trypanosoma brucei casein kinase I, isoform 2 0.0108 0.0191 0.1175
Entamoeba histolytica protein kinase, putative 0.0128 0.0288 0.1863
Leishmania major protein kinase, putative 0.0145 0.0369 0.3102
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0108 0.0191 0.1532
Loa Loa (eye worm) hypothetical protein 0.0126 0.0277 0.0268
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.1104 0.1103
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0218 0.0218
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.007 0.0009 0.0009
Entamoeba histolytica serine/threonine protein kinase, putative 0.0089 0.0098 0.0598
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0104 0.0169 0.0169
Schistosoma mansoni tyrosine kinase 0.1213 0.5496 0.5521
Echinococcus multilocularis raf serine:threonine protein kinase 0.0107 0.0184 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0191 0.0184
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.024 0.1704
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0083 0.0071 0.033
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0223 0.074 0.074
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0083 0.0071 0.033
Trypanosoma brucei SNF1-related protein kinases, putative 0.0089 0.0098 0.029
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0128 0.0288 0.2266
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0159 0.0435 0.3496
Brugia malayi Protein kinase domain containing protein 0.1108 0.4992 0.501
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0071 0.0103
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0159 0.0435 0.0428
Schistosoma mansoni tyrosine kinase 0.0408 0.1629 0.163
Brugia malayi Protein kinase domain containing protein 0.0126 0.0277 0.0262
Loa Loa (eye worm) TK protein kinase 0.0183 0.0549 0.0542
Loa Loa (eye worm) hypothetical protein 0.0236 0.0805 0.08
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0157 0.0423 1
Brugia malayi Protein kinase domain containing protein 0.0201 0.0636 0.0624
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0257 0.025
Schistosoma mansoni nck2/grb4 0.0099 0.0148 0.014
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.024 0.0232
Plasmodium falciparum serine/threonine protein kinase 0.0082 0.0068 0.0277
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0196 0.0615 0.0615
Brugia malayi phosphoinositide-dependent protein kinase I 0.0081 0.006 0.0044
Brugia malayi serine/threonine-protein kinase 6 0.0145 0.0369 0.0355
Plasmodium falciparum serine/threonine protein kinase KIN 0.0089 0.0098 0.111
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Schistosoma mansoni protein kinase 0.0092 0.0116 0.0108
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.024 0.1545
Echinococcus granulosus dual specificity 0.0085 0.0082 0.0082
Trypanosoma brucei protein kinase, putative 0.0128 0.0288 0.2096
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.01 0.0154 0.268
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0212 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0184 0.0177
Brugia malayi map kinase activated protein kinase protein 2 0.0396 0.1571 0.1566
Loa Loa (eye worm) hypothetical protein 0.0503 0.2085 0.2088
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0335 0.1282 0.1274
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0432 0.1743 0.1743
Onchocerca volvulus 0.0326 0.1238 0.5071
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0089 0.0098 0.0603
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.015 0.2526
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0087 0.009 0.0082
Schistosoma mansoni tyrosine kinase 0.0264 0.094 0.0937
Brugia malayi Protein kinase domain containing protein 0.0603 0.2566 0.2567
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0645 0.0641
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.024 0.1704
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0201 0.0636 0.0636
Plasmodium vivax serine/threonine protein kinase, putative 0.0082 0.0068 0.0353
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.074 0.0736
Trypanosoma cruzi casein kinase, putative 0.0108 0.0191 0.1532
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0223 0.074 0.074
Echinococcus multilocularis tyrosine protein kinase shark 0.0341 0.1309 0.1309
Echinococcus granulosus tyrosine protein kinase Fyn 0.0282 0.1025 0.1025
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0085 0.0082 0.0132
Brugia malayi SH2 domain containing protein 0.0126 0.0277 0.0262
Echinococcus multilocularis tyrosine protein kinase 0.0306 0.1141 0.1141
Echinococcus granulosus roundabout 2 0.0135 0.0321 0.0321
Brugia malayi Fes/CIP4 homology domain containing protein 0.0114 0.0219 0.0205
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0084 0.0075 0.0071
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0072 0.0016 0.0006
Echinococcus granulosus CDC7 cell division cycle 7 0.0089 0.01 0.01
Brugia malayi intracellular kinase 0.0128 0.0288 0.0274
Echinococcus multilocularis death associated protein kinase 1 0.0853 0.3767 0.3767
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1278 0.5805 0.5805
Brugia malayi serine/threonine-protein kinase PAK 7 0.0233 0.0788 0.0777
Trypanosoma cruzi casein kinase, putative 0.0108 0.0191 0.1532
Brugia malayi serine/threonine protein kinase 6 0.0145 0.0369 0.0355
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.007 0.0008 0.0008
Echinococcus granulosus protein kinase c iota type 0.0294 0.1081 0.1081
Schistosoma mansoni hypothetical protein 0.0103 0.0164 0.0157
Loa Loa (eye worm) AGC/PKN protein kinase 0.0298 0.1104 0.1101
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0636 0.0632
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.006 0.0052
Schistosoma mansoni hypothetical protein 0.0103 0.0164 0.0157
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0154 0.0409 0.3702
Brugia malayi SH2 domain containing protein 0.0432 0.1743 0.1739
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0154 0.0409 0.0401
Entamoeba histolytica serine/threonine protein kinase, putative 0.0285 0.104 0.6874
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0089 0.0098 0.0098
Echinococcus granulosus casein kinase I alpha 0.0108 0.0191 0.0191
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0082 0.0205
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0164 0.0459 0.0459
Echinococcus granulosus growth factor receptor bound protein 2 0.0112 0.021 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0098 0.009
Echinococcus granulosus tyrosine protein kinase HCK 0.0183 0.0549 0.0549
Entamoeba histolytica protein kinase, putative 0.0301 0.1119 0.74
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.0715 0.6185
Loa Loa (eye worm) TK/INSR protein kinase 0.2141 0.9948 1
Echinococcus multilocularis protein kinase c iota type 0.0294 0.1081 0.1081
Echinococcus granulosus protein kinase 0.0092 0.0116 0.0116
Echinococcus multilocularis myosin iiia 0.0084 0.0075 0.0075
Echinococcus granulosus tyrosine protein kinase Src64B 0.0282 0.1025 0.1025
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0082 0.0068 0.0299
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0164 0.0458 0.0452
Brugia malayi Protein kinase domain containing protein 0.0168 0.0478 0.0465
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0222 0.1534
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0084 0.0075 0.0067
Toxoplasma gondii casein kinase I 0.0108 0.0191 0.1313
Schistosoma mansoni protein kinase 0.01 0.015 0.0142
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0099 0.0148 0.014
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0145 0.0369 0.2405
Echinococcus multilocularis 0.0122 0.0255 0.0255
Echinococcus multilocularis epidermal growth factor receptor 0.1488 0.6812 0.6812
Entamoeba histolytica protein kinase, putative 0.01 0.0154 0.0966
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0218 0.0718 0.0706
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0282 0.1025 0.1025
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0264 0.094 0.094
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0164 0.0458 0.045
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0282 0.1025 0.1025
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0212 0.0203
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.0435 0.3966
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.071 0.0706
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0089 0.0098 0.029
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0212 0.1743
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0216 0.071 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0409 0.0403
Echinococcus multilocularis serine threonine protein kinase 0.0209 0.0676 0.0676
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0432 0.1747 0.1747
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0104 0.0169 0.0162
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0083 0.0071 0.0129
Trichomonas vaginalis STE family protein kinase 0.0085 0.0082 0.0207
Onchocerca volvulus 0.0489 0.202 0.8291
Leishmania major protein kinase, putative 0.0154 0.0409 0.3507
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.031
Entamoeba histolytica protein kinase domain containing protein 0.01 0.015 0.0943
Entamoeba histolytica protein kinase domain containing protein 0.0145 0.0369 0.2405
Echinococcus multilocularis casein kinase I gamma 0.0214 0.0697 0.0697
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.01 0.0154 0.0154
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Echinococcus multilocularis roundabout 2 0.0135 0.0321 0.0321
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.024 0.1775
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0164 0.0459 0.0452
Loa Loa (eye worm) hypothetical protein 0.1044 0.4682 0.4701
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0212 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.024 0.024
Loa Loa (eye worm) AUR protein kinase 0.0145 0.0369 0.0361
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Echinococcus granulosus insulin receptor 0.2141 0.9948 0.9948
Entamoeba histolytica protein kinase 2, putative 0.0157 0.0423 0.2763
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0186 0.0564 0.0564
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0212 0.144
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0166 0.0466 0.4277
Plasmodium vivax casein kinase 1, putative 0.0108 0.0191 0.3706
Loa Loa (eye worm) hypothetical protein 0.0367 0.1433 0.1432
Trypanosoma brucei aurora B kinase 0.0145 0.0369 0.2869
Loa Loa (eye worm) hypothetical protein 0.0113 0.0212 0.0203
Brugia malayi Sex muscle abnormal protein 5 0.0099 0.0148 0.0132
Schistosoma mansoni tyrosine kinase 0.0282 0.1025 0.1022
Schistosoma mansoni ste20-related kinase 0.0205 0.0658 0.0653
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0084 0.0075 0.0075
Echinococcus multilocularis transfer RNA-Thr 0.1203 0.5444 0.5444
Loa Loa (eye worm) hypothetical protein 0.0122 0.0255 0.0246
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0577 0.488
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0134 0.0317 0.2544
Schistosoma mansoni vesicular amine transporter 0.0084 0.0075 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus multilocularis Immunoglobulin 0.0084 0.0075 0.0075
Loa Loa (eye worm) SRC-1 0.0282 0.1025 0.1021
Giardia lamblia Kinase, CDC7 0.0089 0.01 0.0331
Echinococcus granulosus mitogen activated protein kinase 3 0.0083 0.0071 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0216 0.071 0.071
Echinococcus granulosus tyrosine protein kinase 0.0306 0.1141 0.1141
Giardia lamblia Kinase, CMGC CLK 0.0154 0.0409 0.3507
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0282 0.1025 0.1025
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0409 0.0403
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0564 0.0559
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Trichomonas vaginalis STE family protein kinase 0.0136 0.0324 0.2495
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0244 0.0844 0.0844
Loa Loa (eye worm) TK protein kinase 0.0306 0.1141 0.1138
Entamoeba histolytica protein kinase, putative 0.0081 0.006 0.0342
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0082 0.0205
Brugia malayi Protein kinase domain containing protein 0.0193 0.0598 0.0586
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0186 0.0564 0.0564
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.021 0.068 0.068
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0128 0.0288 0.0288
Mycobacterium ulcerans hypothetical protein 0.0102 0.0163 0.5
Echinococcus granulosus raf serine:threonine protein kinase 0.0107 0.0184 0.0184
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0083 0.0071 0.0061
Brugia malayi Protein kinase domain containing protein 0.0301 0.1119 0.111
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0288 0.1863
Trypanosoma cruzi polo-like protein kinase, putative 0.0285 0.104 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0119 0.0244 0.0244
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0125 0.027 0.027
Echinococcus granulosus geminin 0.0197 0.0617 0.0617
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0154 0.0154
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0603 0.2566 0.2572
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0089 0.0098 0.0089
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0128 0.0288 0.2263
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0085 0.0082 0.0082
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0099 0.0148 0.0138
Brugia malayi Protein kinase domain containing protein 0.0118 0.024 0.0226
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0216 0.071 0.071
Trypanosoma brucei protein kinase, putative 0.0083 0.0071 0.0029
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.0435 0.0435
Entamoeba histolytica protein kinase domain containing protein 0.0097 0.0135 0.0846
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0157 0.0423 0.0423
Plasmodium falciparum cGMP-dependent protein kinase 0.0134 0.0317 0.7086
Leishmania major protein kinase A catalytic subunit 0.0113 0.0212 0.1488
Trypanosoma cruzi casein kinase, putative 0.0108 0.0191 0.1532
Brugia malayi Protein kinase domain containing protein 0.0089 0.01 0.0084
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0085 0.0082 0.0082
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0212 0.4279
Echinococcus multilocularis dual specificity 0.0122 0.0257 0.0257
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0218 0.0718 0.0712
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0212 0.152
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0285 0.104 0.1036
Schistosoma mansoni protein kinase 0.0193 0.0598 0.0593
Echinococcus granulosus serine:threonine protein kinase 3 0.0257 0.0907 0.0907
Echinococcus granulosus serine:threonine kinase SAD 1 0.0089 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0144 0.0365 0.0357
Plasmodium falciparum calcium-dependent protein kinase 3 0.01 0.0154 0.2623
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0097 0.0135 0.0764
Loa Loa (eye worm) CDC7 protein kinase 0.0089 0.01 0.009
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0324 0.2495
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.01 0.0378
Echinococcus multilocularis insulin receptor 0.2141 0.9948 0.9948
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0145 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0308 0.1149 0.1146
Echinococcus multilocularis CDC7 cell division cycle 7 0.0089 0.01 0.01
Schistosoma mansoni protein kinase 0.0108 0.0191 0.0184
Brugia malayi putative serine/threonine kinase SADA gamma 0.0089 0.0098 0.0082
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0073 0.0023 0.0013
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0503 0.2085 0.2085
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0335 0.128 0.128
Echinococcus granulosus activated cdc42 kinase 1 0.1203 0.5444 0.5444
Loa Loa (eye worm) hypothetical protein 0.0182 0.0545 0.0538
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.024 0.2021
Brugia malayi Stress-activated protein kinase jnk-1 0.0265 0.0943 0.0933
Leishmania major protein kinase, putative 0.0097 0.0135 0.0696
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0097 0.0135 0.0135
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0128 0.0288 0.0288
Onchocerca volvulus Serine\/threonine kinase homolog 0.0164 0.0459 0.1866
Echinococcus multilocularis geminin 0.0197 0.0617 0.0617
Schistosoma mansoni tyrosine kinase 0.0341 0.1309 0.1308
Schistosoma mansoni tyrosine kinase 0.0503 0.2085 0.2089
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Entamoeba histolytica hypothetical protein 0.0122 0.0257 0.1656
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0126 0.0277 0.179
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.0191 0.1241
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0285 0.104 0.104
Onchocerca volvulus 0.0186 0.0564 0.2299
Brugia malayi Protein kinase domain 0.0085 0.0082 0.0066
Onchocerca volvulus 0.0126 0.0277 0.1115
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0317 0.0317
Brugia malayi Kinase associated domain 1 family protein 0.0103 0.0164 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0288 0.2154
Echinococcus granulosus casein kinase I alpha 0.0108 0.0191 0.0191
Brugia malayi Protein kinase domain containing protein 0.0303 0.1125 0.1117
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0157 0.0423 1
Schistosoma mansoni adapter molecule crk 0.0099 0.0148 0.014
Schistosoma mansoni ephrin receptor 0.0075 0.0034 0.0026
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0282 0.1025 0.1025
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0218 0.149
Plasmodium vivax calcium-dependent protein kinase, putative 0.01 0.0154 0.268
Brugia malayi Protein kinase c protein 2 0.0115 0.0225 0.021
Echinococcus multilocularis protein kinase shaggy 0.0128 0.0288 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Schistosoma mansoni tyrosine kinase 0.0105 0.0175 0.0168
Loa Loa (eye worm) TK/ROR protein kinase 0.0086 0.0087 0.0077
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0218 0.0218
Entamoeba histolytica protein kinase, putative 0.0168 0.0478 0.3128
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0232 0.0217
Echinococcus multilocularis dual specificity protein kinase clk2 0.0154 0.0409 0.0409
Brugia malayi Protein kinase domain containing protein 0.0188 0.0577 0.0564
Echinococcus granulosus mitogen activated protein kinase 11 0.0159 0.0435 0.0435
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.024 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0369 0.2922
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.024 0.024
Echinococcus multilocularis mitogen activated protein kinase 3 0.0083 0.0071 0.0071
Schistosoma mansoni nephrin 0.0117 0.0232 0.0225
Schistosoma mansoni protein kinase 0.0097 0.0135 0.0128
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0164 0.0459 0.0459
Brugia malayi Protein kinase domain containing protein 0.0214 0.0697 0.0685
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.024 0.1704
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0335 0.1282 0.128
Plasmodium vivax serine/threonine kinase-1, putative 0.0154 0.0409 0.9608
Loa Loa (eye worm) hypothetical protein 0.0099 0.0148 0.0138
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.031
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.0435 0.3966
Loa Loa (eye worm) hypothetical protein 0.014 0.0343 0.0335
Echinococcus multilocularis dual specificity 0.0085 0.0082 0.0082
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0128 0.0288 0.028
Onchocerca volvulus 0.0126 0.0277 0.1115
Schistosoma mansoni protein kinase 0.0097 0.0135 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0478 0.3947
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0318 0.0311
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0168 0.0478 0.0478
Entamoeba histolytica protein kinase, putative 0.0122 0.0257 0.1656
Schistosoma mansoni tyrosine kinase 0.1213 0.5496 0.5521
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0212 0.4234
Echinococcus granulosus casein kinase i 0.0108 0.0191 0.0191
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0092 0.0116 0.0106
Echinococcus multilocularis NCK adaptor protein 0.0112 0.021 0.021
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0115 0.0222 0.0222
Brugia malayi STE20-like kinase MST 0.0257 0.0907 0.0897
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0264 0.094 0.094
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.024 0.1795
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0282 0.1025 0.1025
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0218 0.0218
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0083 0.0071 0.0031
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0257 0.2187
Onchocerca volvulus 0.0128 0.0288 0.1161
Schistosoma mansoni serine/threonine-protein kinase 0.0166 0.0466 0.0461
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0097 0.0135 0.0643
Loa Loa (eye worm) hypothetical protein 0.0084 0.0075 0.0065
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0203 0.0645 0.0645
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.024 0.024
Toxoplasma gondii histone kinase SNF1, putative 0.0089 0.0098 0.0398
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.024 0.1775
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0154 0.0138
Brugia malayi protein kinase C3,putative 0.0158 0.0428 0.0415
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.0191 0.1241
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0085 0.0082 0.0235
Schistosoma mansoni serine/threonine kinase 0.0217 0.0715 0.0711
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0282 0.1025 0.1025
Brugia malayi Variant SH3 domain containing protein 0.0104 0.0169 0.0154
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0154 0.0154
Echinococcus multilocularis hypothetical protein 0.0103 0.0164 0.0164
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0212 0.1743
Brugia malayi Fibronectin type III domain containing protein 0.0095 0.0128 0.0112
Echinococcus multilocularis calcium activated potassium channel 0.0135 0.0318 0.0318
Brugia malayi Immunoglobulin I-set domain containing protein 0.0656 0.2821 0.2824
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0218 0.0218
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0126 0.0275 0.2133
Plasmodium falciparum calcium-dependent protein kinase 4 0.01 0.0154 0.2623
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0084 0.0075 0.0445
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.01 0.0154 0.0942
Loa Loa (eye worm) hypothetical protein 0.0144 0.0362 0.0354
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.0435 0.0435
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0212 0.0203
Giardia lamblia Kinase, CMGC DYRK 0.0085 0.0082 0.0142
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0256 0.1647
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.0435 0.0435
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0085 0.0082 0.0082
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.024 0.0232
Schistosoma mansoni cell adhesion molecule 0.0113 0.0216 0.0209
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0285 0.104 0.104
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0089 0.0098 0.0313
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.0338 0.0329
Trichomonas vaginalis STE family protein kinase 0.0085 0.0082 0.0207
Brugia malayi Protein kinase domain containing protein 0.0164 0.0459 0.0446
Giardia lamblia Kinase, CMGC CK2 0.01 0.015 0.0846
Brugia malayi ephrin receptor 1 precursor 0.0095 0.0128 0.0112
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.024 0.2021
Entamoeba histolytica protein kinase, putative 0.0093 0.0121 0.0747
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0087 0.009 0.0522
Entamoeba histolytica protein kinase, putative 0.0082 0.0068 0.0395
Loa Loa (eye worm) TK/ALK protein kinase 0.0303 0.1125 0.1122
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0081 0.0059 0.0059
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0102 0.0164 0.0164
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0085 0.0082 0.0438
Schistosoma mansoni growth factor receptor-bound protein 0.0112 0.021 0.0203
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0087 0.009 0.0212
Plasmodium vivax glycogen synthase kinase 3, putative 0.0128 0.0288 0.6332
Schistosoma mansoni serine/threonine protein kinase 0.021 0.068 0.0676
Trichomonas vaginalis STE family protein kinase 0.0084 0.0075 0.0145
Echinococcus multilocularis aurora kinase A 0.0145 0.0369 0.0369
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0186 0.0564 0.0552
Echinococcus multilocularis protein KINase family member (kin 25) 0.0503 0.2085 0.2085
Onchocerca volvulus 0.0195 0.0608 0.2477
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0097 0.0135 0.0974
Brugia malayi casein kinase I 0.0108 0.0191 0.0176
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0201 0.0636 0.063
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0478 0.0472
Echinococcus multilocularis casein kinase I alpha 0.0108 0.0191 0.0191
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0203 0.0645 0.0633
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Loa Loa (eye worm) AGC/PKG protein kinase 0.0134 0.0317 0.0308
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.021 0.068 0.068
Echinococcus granulosus dual specificity protein kinase clk2 0.0154 0.0409 0.0409
Brugia malayi Protein kinase domain containing protein 0.0081 0.006 0.0044
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0145 0.0369 0.2405
Echinococcus multilocularis casein kinase I delta 0.0108 0.0191 0.0191
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.01 0.0154 0.268
Schistosoma mansoni tyrosine kinase 0.0096 0.0133 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0878 0.0875
Echinococcus granulosus tyrosine protein kinase Fyn 0.0282 0.1025 0.1025
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0256 0.1647
Entamoeba histolytica protein kinase, putative 0.0073 0.002 0.0078
Schistosoma mansoni hypothetical protein 0.0087 0.009 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.104 0.1038
Brugia malayi SRC-1 0.0282 0.1025 0.1015
Entamoeba histolytica PH domain containing protein kinase, putative 0.0166 0.0466 0.3051
Brugia malayi MH2 domain containing protein 0.0139 0.0338 0.0323
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0082 0.0068 0.0099
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0201 0.0636 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0884 0.0881
Trypanosoma cruzi aurora B kinase, putative 0.0145 0.0369 0.3308
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0154 0.0409 0.3702
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0288 0.2154
Echinococcus granulosus c-Jun N-terminal kinases 0.0265 0.0943 0.0943
Schistosoma mansoni protein kinase 0.0085 0.0082 0.0074
Loa Loa (eye worm) hypothetical protein 0.0124 0.0268 0.026
Brugia malayi Tyrosine-protein kinase abl-1 0.0129 0.0291 0.0277
Loa Loa (eye worm) AGC/NDR protein kinase 0.0168 0.0478 0.0471
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.01 0.0378
Brugia malayi Casein kinase II, alpha chain 0.01 0.015 0.0135
Brugia malayi Egg laying defective protein 4 0.0134 0.0317 0.0302
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.031 0.2364
Brugia malayi C1-like domain containing protein 0.0218 0.0718 0.0706
Onchocerca volvulus 0.0294 0.1084 0.4439
Trypanosoma brucei Casein kinase II 0.01 0.015 0.0782
Brugia malayi Immunoglobulin I-set domain containing protein 0.0286 0.1045 0.1036
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.015 0.0141
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0212 0.1376
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0154 0.0884
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0098 0.009
Giardia lamblia Kinase, CMGC CDK 0.0118 0.024 0.1775
Echinococcus granulosus tyrosine protein kinase Srms 0.0537 0.2248 0.2248
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Schistosoma mansoni protein kinase 0.0343 0.1317 0.1316
Brugia malayi Furin-like cysteine rich region family protein 0.1488 0.6812 0.6842
Echinococcus granulosus calcium activated potassium channel 0.0135 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0084 0.0075 0.0065
Brugia malayi Hr1 repeat family protein 0.0298 0.1104 0.1096
Schistosoma mansoni hypothetical protein 0.0197 0.0617 0.0612
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0211 0.0686 0.068
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0236 0.0805 0.0794
Echinococcus granulosus serine/threonine protein kinase 0.0166 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.1203 0.5444 0.5468
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0071 0.0103
Brugia malayi hypothetical protein 0.0095 0.0128 0.0112
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0159 0.0435 0.378
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0122 0.0257 0.0248
Brugia malayi Protein kinase domain containing protein 0.0154 0.0409 0.0395
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0154 0.0154
Schistosoma mansoni protein kinase 0.0145 0.0369 0.0363
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.024 0.1545
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus granulosus neuroglian 0.0106 0.018 0.018
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0432 0.1743 0.1743
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0119 0.0244 0.0244
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.024 0.1642
Echinococcus granulosus serine threonine protein kinase nrc 0.0157 0.0423 0.0423
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0369 0.0363
Brugia malayi MAP kinase sur-1 0.0083 0.0071 0.0055
Onchocerca volvulus 0.0087 0.009 0.0345
Echinococcus multilocularis c src tyrosine kinase 0.0164 0.0458 0.0458
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0154 0.0409 0.3244
Echinococcus multilocularis dual specificity 0.0085 0.0082 0.0082
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0089 0.0098 0.0603
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0288 0.1863
Loa Loa (eye worm) hypothetical protein 0.0089 0.0098 0.0089
Schistosoma mansoni tyrosine kinase 0.028 0.1014 0.1011
Entamoeba histolytica casein kinase, putative 0.0108 0.0191 0.1218
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.01 0.0378
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0087 0.009 0.008
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0212 0.1743
Loa Loa (eye worm) AUR protein kinase 0.0145 0.0369 0.0361
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0085 0.0082 0.0082
Onchocerca volvulus 0.0089 0.01 0.0386
Loa Loa (eye worm) hypothetical protein 0.0367 0.1433 0.1432
Giardia lamblia Kinase, AGC AKT 0.0117 0.0232 0.1689
Loa Loa (eye worm) hypothetical protein 0.0114 0.0218 0.0209
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0354 0.137 0.137
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0317 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus granulosus dual specificity 0.0085 0.0082 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Loa Loa (eye worm) hypothetical protein 0.009 0.0103 0.0094
Brugia malayi Protein kinase domain containing protein 0.0194 0.0603 0.059
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0282 0.1025 0.1025
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0097 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0148 0.038 0.0373
Echinococcus granulosus protein kinase shaggy 0.0128 0.0288 0.0288
Brugia malayi serine/threonine-protein kinase plk-2 0.0285 0.104 0.1031
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0154 0.0154
Schistosoma mansoni kinase 0.0297 0.1096 0.1094
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.024 0.0233
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0369 0.2922
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0193 0.0598 0.0591
Schistosoma mansoni ephrin receptor 0.0129 0.0291 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0082 0.0205
Loa Loa (eye worm) AUR protein kinase 0.0145 0.0369 0.0361
Toxoplasma gondii AGC kinase 0.0113 0.0212 0.152
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0084 0.0075 0.0445
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Echinococcus multilocularis serine:threonine protein kinase 3 0.0257 0.0907 0.0907
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0369 0.2922
Echinococcus multilocularis dual specificity 0.0085 0.0082 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.137 0.137
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0122 0.0257 0.1946
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0257 0.2187
Loa Loa (eye worm) hypothetical protein 0.0438 0.1775 0.1776
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.0338 0.0329
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0244 0.0844 0.0844
Leishmania major protein kinase, putative 0.0084 0.0075 0.0077
Echinococcus multilocularis serine:threonine protein kinase 38 0.0168 0.0478 0.0478
Echinococcus granulosus casein kinase I alpha 0.0108 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0124 0.0268 0.026
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0083 0.0071 0.033
Echinococcus granulosus protein kinase c epsilon type 0.0211 0.0686 0.0686
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.031 0.2364
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0478 0.0472
Loa Loa (eye worm) hypothetical protein 0.0082 0.0066 0.0056
Schistosoma mansoni tyrosine kinase 0.0273 0.0984 0.0982
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1043 0.4677 0.4677
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0087 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0186 0.0564 0.0558
Trypanosoma brucei rac serine-threonine kinase, putative 0.0301 0.1119 1
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.024 0.1642
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0089 0.0098 0.1179
Onchocerca volvulus 0.0144 0.0362 0.1466
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0099 0.0148 0.0138
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0409 0.3294
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0233 0.0788 0.0783
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0081 0.006 0.005
Giardia lamblia Kinase, AGC PKA 0.0157 0.0423 0.3656
Echinococcus granulosus casein kinase I gamma 0.0214 0.0697 0.0697
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.1238 0.1237
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0354 0.137 0.1363
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0217 0.0715 0.0709
Loa Loa (eye worm) hypothetical protein 0.0103 0.0164 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0068 0.006
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.01 0.0154 0.0816
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0196 0.0615 0.0615
Brugia malayi protein-tyrosine kinase 0.0244 0.0844 0.0833
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0104 0.0169 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0071 0.0063
Loa Loa (eye worm) TK protein kinase 0.037 0.1448 0.1447
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0343 0.1317 0.1315
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0081 0.006 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0878 0.0875
Loa Loa (eye worm) hypothetical protein 0.0603 0.2566 0.2572
Brugia malayi Protein kinase domain containing protein 0.0122 0.0257 0.0242
Entamoeba histolytica protein kinase, putative 0.0073 0.002 0.0078
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.045 0.1834 0.1835
Brugia malayi Protein kinase domain containing protein 0.0114 0.0218 0.0203
Echinococcus granulosus serine:threonine protein kinase N2 0.0131 0.0299 0.0299
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0218 0.0209
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0128 0.0288 0.2497
Schistosoma mansoni tyrosine kinase 0.0164 0.0458 0.0452
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0082 0.0068 0.0058
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.01 0.0154 0.268
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0282 0.1025 0.1025
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0081 0.0059 0.0059
Onchocerca volvulus 0.0089 0.01 0.0386
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0157 0.0423 0.0423
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0432 0.1747 0.1747
Echinococcus granulosus ephrin type A receptor 4 A 0.0129 0.0291 0.0291
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0082 0.0487
Brugia malayi Protein kinase domain containing protein 0.045 0.1834 0.183
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.024 0.024
Echinococcus multilocularis N chimaerin 0.0104 0.0169 0.0169
Onchocerca volvulus 0.0126 0.0277 0.1115
Brugia malayi Protein kinase domain containing protein 0.0082 0.0068 0.0052
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0089 0.0098 0.0313
Trichomonas vaginalis STE family protein kinase 0.0085 0.0082 0.0207
Schistosoma mansoni protein kinase 0.0085 0.0082 0.0074
Onchocerca volvulus 0.0126 0.0277 0.1115
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0265 0.0943 0.0943
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0188 0.0577 0.057
Echinococcus multilocularis nervana 2 0.0125 0.027 0.027
Giardia lamblia Aurora kinase 0.0145 0.0369 0.3102
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0253 0.0884 0.088
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.01 0.0154 0.0942
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Onchocerca volvulus Tyrosine kinase homolog 0.0576 0.2435 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Echinococcus multilocularis protein kinase c epsilon type 0.0211 0.0686 0.0686
Brugia malayi Protein kinase domain containing protein 0.1203 0.5444 0.5465
Brugia malayi Protein kinase domain containing protein 0.0126 0.0277 0.0262
Brugia malayi Protein kinase domain containing protein 0.0217 0.0715 0.0703
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0282 0.1025 0.1025
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0212 0.1488
Brugia malayi hypothetical protein 0.0126 0.0277 0.0262
Plasmodium vivax unspecified product 0.01 0.015 0.2585
Echinococcus granulosus nervana 2 0.0125 0.027 0.027
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0212 0.1743
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0081 0.006 0.005
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0148 0.0132
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0436 0.1763 0.1763
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0071 0.0103
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0285 0.104 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0193 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0087 0.009 0.008
Echinococcus multilocularis serine:threonine protein kinase N2 0.0168 0.0478 0.0478
Echinococcus granulosus tyrosine protein kinase ABL1 0.0335 0.128 0.128
Toxoplasma gondii AGC kinase 0.0292 0.1076 1
Onchocerca volvulus 0.0126 0.0277 0.1115
Schistosoma mansoni tyrosine kinase 0.1488 0.6812 0.6845
Echinococcus granulosus hypothetical protein 0.0122 0.0255 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0697 0.0692
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0122 0.0257 0.18
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0154 0.0409 0.3702
Schistosoma mansoni vam6/vps39 related 0.0087 0.009 0.0082
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.024 0.024
Schistosoma mansoni rap gtpase-activating protein 0.0087 0.009 0.0082
Schistosoma mansoni protein kinase 0.0436 0.1763 0.1766
Echinococcus multilocularis tyrosine protein kinase Blk 0.0244 0.0844 0.0844
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0083 0.0071 0.0061
Echinococcus granulosus epidermal growth factor receptor 0.1278 0.5805 0.5805
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0083 0.0071 0.0029
Loa Loa (eye worm) hypothetical protein 0.014 0.0343 0.0335
Trypanosoma brucei protein kinase, putative 0.0097 0.0135 0.0643
Echinococcus granulosus fibroblast growth factor receptor 4 0.0264 0.094 0.094
Schistosoma mansoni protein kinase C mu 0.0218 0.0718 0.0714
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0154 0.0146
Trypanosoma brucei polo-like protein kinase 0.0285 0.104 0.9249
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.0191 0.0182
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0176 0.0516 0.0509
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.015 0.0907
Echinococcus granulosus cyclin dependent kinase 0.0118 0.024 0.024
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0257 0.1656
Echinococcus multilocularis casein kinase I alpha 0.0108 0.0191 0.0191
Schistosoma mansoni tyrosine kinase 0.0282 0.1025 0.1022
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0354 0.137 0.1369
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.1571 0.1572
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0097 0.0135 0.0974
Echinococcus multilocularis tyrosine protein kinase Abl 0.0244 0.0841 0.0841
Brugia malayi cell division control protein 2 homolog 0.0118 0.024 0.0226
Plasmodium vivax protein kinase Crk2 0.0118 0.024 0.5037
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.0435 0.0435
Loa Loa (eye worm) TK/ABL protein kinase 0.0335 0.128 0.1277
Entamoeba histolytica protein kinase, putative 0.0082 0.0068 0.0395
Trypanosoma cruzi casein kinase, putative 0.0108 0.0191 0.1532
Loa Loa (eye worm) hypothetical protein 0.0084 0.0077 0.0067
Brugia malayi Temporarily assigned gene name protein 59 0.013 0.0295 0.0281
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0085 0.0082 0.0142
Echinococcus granulosus cGMP dependent protein kinase 0.0134 0.0317 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0318 0.0311
Echinococcus granulosus tyrosine protein kinase Lyn 0.0314 0.1178 0.1178
Loa Loa (eye worm) hypothetical protein 0.0438 0.1775 0.1776
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.024 0.2021
Schistosoma mansoni serine/threonine-protein kinase 0.0166 0.0466 0.0461
Loa Loa (eye worm) hypothetical protein 0.009 0.0103 0.0094
Echinococcus granulosus nervana 2 0.0125 0.027 0.027
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.01 0.0154 0.0144
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0497 0.2056 0.2056
Brugia malayi Protein kinase domain containing protein 0.0354 0.137 0.1363
Echinococcus multilocularis tyrosine protein kinase Srms 0.0244 0.0844 0.0844
Loa Loa (eye worm) TK/EGFR protein kinase 0.1488 0.6812 0.6844
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0343 0.1317 0.1317
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0108 0.0191 0.0182
Entamoeba histolytica protein kinase, putative 0.0183 0.0549 0.3601
Schistosoma mansoni growth factor receptor-bound protein 0.0099 0.0148 0.014
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0216 0.071 0.071
Echinococcus multilocularis casein kinase i 0.0108 0.0191 0.0191
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0223 0.074 0.0734
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0396 0.1571 0.1571
Echinococcus multilocularis rac serine:threonine kinase 0.0166 0.0466 0.0466
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0212 0.1376
Trypanosoma cruzi casein kinase II, putative 0.01 0.015 0.112
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0212 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0098 0.009
Entamoeba histolytica hypothetical protein 0.0383 0.1509 1
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0145 0.0369 0.0369
Echinococcus multilocularis neuroglian 0.0106 0.018 0.018
Entamoeba histolytica protein kinase, putative 0.0102 0.016 0.1007
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0317 0.0317
Plasmodium falciparum calcium-dependent protein kinase 1 0.01 0.0154 0.2623
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0087 0.009 0.0522
Echinococcus multilocularis tyrosine kinase 0.0126 0.0277 0.0277
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0292 0.1076 0.1072
Echinococcus granulosus tyrosine kinase 0.0126 0.0277 0.0277
Plasmodium falciparum protein kinase, putative 0.0097 0.0135 0.2127
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Onchocerca volvulus Serine\/threonine kinase homolog 0.0285 0.104 0.4257
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0086 0.0087 0.0087
Giardia lamblia Kinase, STE STE20 0.0084 0.0075 0.0077
Loa Loa (eye worm) TK protein kinase 0.0244 0.0844 0.0839
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0082 0.0205
Echinococcus multilocularis growth factor receptor bound protein 2 0.0099 0.0148 0.0148
Schistosoma mansoni tyrosine kinase 0.1278 0.5805 0.5832
Brugia malayi Protein kinase domain containing protein 0.0126 0.0277 0.0262
Loa Loa (eye worm) TK/FER protein kinase 0.0432 0.1743 0.1744
Echinococcus granulosus serine:threonine protein kinase N2 0.0298 0.1104 0.1104
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0154 0.0409 0.3702
Brugia malayi Protein kinase domain containing protein 0.0126 0.0277 0.0262
Giardia lamblia Kinase, NEK 0.0136 0.0324 0.2637
Echinococcus granulosus epidermal growth factor receptor 0.1488 0.6812 0.6812
Echinococcus granulosus aurora kinase A 0.0145 0.0369 0.0369
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0656 0.2821 0.2829
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0577 0.488
Onchocerca volvulus 0.0076 0.0038 0.013
Echinococcus granulosus tyrosine kinase 0.0244 0.0844 0.0844
Onchocerca volvulus 0.0126 0.0277 0.1115
Echinococcus granulosus rho-associated protein kinase 1 0.0326 0.1238 0.1238
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0354 0.137 0.1369
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0497 0.2056 0.2056
Giardia lamblia Kinase, NEK 0.0136 0.0324 0.2637
Echinococcus granulosus tyrosine protein kinase shark 0.0341 0.1309 0.1309
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0203 0.0645 0.0639
Schistosoma mansoni protein kinase 0.0436 0.1763 0.1766
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0282 0.1025 0.1025
Loa Loa (eye worm) hypothetical protein 0.0241 0.0831 0.0826
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0087 0.0077
Echinococcus granulosus activin receptor type 0.0097 0.0135 0.0135
Echinococcus multilocularis epidermal growth factor receptor 0.1278 0.5805 0.5805
Echinococcus granulosus activated cdc42 kinase 1 0.1203 0.5444 0.5444
Giardia lamblia Kinase, CK1 Casein kinase 0.0108 0.0191 0.1271
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0318 0.0311
Brugia malayi Tyrosine-protein kinase abl-1 0.0244 0.0841 0.083
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0071 0.0103
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0098 0.0313
Echinococcus granulosus NDR protein kinase 0.0168 0.0478 0.0478
Plasmodium falciparum calcium-dependent protein kinase 5 0.01 0.0154 0.2623
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0104 0.0169 0.0169
Entamoeba histolytica protein kinase, putative 0.0122 0.0257 0.1656
Schistosoma mansoni tyrosine kinase 0.2141 0.9948 1
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.024 0.2021
Echinococcus granulosus protein kinase C gamma type 0.0209 0.0676 0.0676
Entamoeba histolytica protein kinase, putative 0.0292 0.1076 0.7112
Loa Loa (eye worm) hypothetical protein 0.0144 0.0362 0.0354
Schistosoma mansoni tyrosine kinase 0.1213 0.5496 0.5521
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0314 0.0308
Schistosoma mansoni serine/threonine kinase 0.0168 0.0478 0.0472
Schistosoma mansoni hypothetical protein 0.0197 0.0617 0.0612
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0603 0.2566 0.2572
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.0191 0.1241
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0265 0.0943 0.0939
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0436 0.1763 0.1763
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0317 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0943 0.0941
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Trypanosoma cruzi Protein kinase B 0.0166 0.0466 0.4277
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0168 0.0478 0.0478
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.0191 0.0182
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Echinococcus granulosus casein kinase I delta 0.0108 0.0191 0.0191
Brugia malayi Protein kinase domain containing protein 0.0343 0.1317 0.1309
Schistosoma mansoni protein kinase 0.0097 0.0135 0.0128
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0136 0.0324 0.2618
Loa Loa (eye worm) hypothetical protein 0.0095 0.0128 0.0118
Loa Loa (eye worm) hypothetical protein 0.021 0.0678 0.0672
Giardia lamblia Kinase, STE STE20 0.0085 0.0082 0.0145
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0347 0.1336 0.1334
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0212 0.0205
Echinococcus granulosus defective proboscis extension response 0.0084 0.0075 0.0075
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0603 0.2566 0.2567
Trichomonas vaginalis AGC family protein kinase 0.0197 0.062 0.5288
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0148 0.0132
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0128 0.0288 0.028
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0168 0.0478 0.0478
Plasmodium falciparum NIMA related kinase 1 0.0136 0.0324 0.7291
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.0128 0.0112
Echinococcus granulosus tyrosine protein kinase Fyn 0.0282 0.1025 0.1025
Echinococcus granulosus dual specificity 0.0122 0.0257 0.0257
Brugia malayi Cam kinase protein 1 0.01 0.0154 0.0138
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0085 0.0082 0.0082
Schistosoma mansoni atypical protein kinase C 0.03 0.111 0.1108
Loa Loa (eye worm) hypothetical protein 0.1138 0.5134 0.5156
Echinococcus granulosus Protein kinase C brain isozyme 0.0251 0.0878 0.0878
Echinococcus multilocularis ephrin type A receptor 4 A 0.0129 0.0291 0.0291
Entamoeba histolytica protein kinase, putative 0.0145 0.0369 0.2405
Echinococcus multilocularis mitogen activated protein kinase 0.0083 0.0071 0.0071
Echinococcus multilocularis casein kinase I alpha 0.0108 0.0191 0.0191
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0085 0.0082 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.071 0.0706
Trichomonas vaginalis STE family protein kinase 0.0085 0.0082 0.0207
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0947 0.4219 0.4235
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0082 0.0205
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0369 0.2922
Echinococcus multilocularis Immunoglobulin 0.0084 0.0075 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.01 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Trypanosoma cruzi polo-like protein kinase, putative 0.0285 0.104 1
Echinococcus granulosus serine:threonine protein kinase Chk2 0.007 0.0009 0.0009
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0078 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.009 0.008
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0251 0.0878 0.0878
Echinococcus multilocularis activin receptor type 0.0097 0.0135 0.0135
Echinococcus multilocularis serine:threonine protein kinase N2 0.0298 0.1104 0.1104
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0098 0.0313
Plasmodium falciparum serine/threonine protein kinase, putative 0.0145 0.0369 0.8527
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0102 0.0164 0.0154
Loa Loa (eye worm) AGC/AKT protein kinase 0.0301 0.1119 0.1115
Brugia malayi hypothetical protein 0.0223 0.074 0.0729
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0212 0.1376
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Loa Loa (eye worm) hypothetical protein 0.0465 0.1902 0.1904
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0257 0.0907 0.0903
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Brugia malayi RhoGAP domain containing protein 0.0104 0.0169 0.0154
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0212 0.0212
Leishmania major protein kinase, putative 0.0154 0.0409 0.3507
Echinococcus multilocularis serine:threonine protein kinase N2 0.0131 0.0299 0.0299
Giardia lamblia Kinase, CMGC MAPK 0.0083 0.0071 0.0031
Toxoplasma gondii AGC kinase 0.0113 0.0212 0.152
Giardia lamblia Kinase, CMGC GSK 0.0128 0.0288 0.2266
Echinococcus granulosus mitogen activated protein kinase 14 0.0159 0.0435 0.0435
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0154 0.0409 0.3449
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0686 0.0682
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Brugia malayi Protein kinase domain containing protein 0.0947 0.4219 0.4232
Echinococcus multilocularis 0.0092 0.0116 0.0116
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0104 0.0169 0.016
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.015 0.015
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0396 0.1571 0.1571
Echinococcus granulosus Vam6:Vps39 protein 0.0087 0.009 0.009
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.007 0.0008 0.0008
Echinococcus granulosus twitchin 0.0138 0.0334 0.0334
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0343 0.1317 0.1317
Toxoplasma gondii aurora kinase 0.0145 0.0369 0.3062
Schistosoma mansoni vav2 0.0113 0.0212 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus multilocularis expressed conserved protein 0.0134 0.0317 0.0317
Entamoeba histolytica protein kinase, putative 0.0085 0.0082 0.0489
Echinococcus multilocularis tyrosine protein kinase HCK 0.0183 0.0549 0.0549
Schistosoma mansoni protein kinase 0.0436 0.1763 0.1766
Loa Loa (eye worm) hypothetical protein 0.0095 0.0128 0.0118
Brugia malayi Temporarily assigned gene name protein 59 0.0087 0.009 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.021 0.068 0.0676
Loa Loa (eye worm) hypothetical protein 0.01 0.0154 0.0144
Echinococcus granulosus Glutaredoxin protein 5 0.0125 0.027 0.027
Echinococcus multilocularis nervana 2 0.0125 0.027 0.027
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0168 0.0478 0.0478
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0081 0.006 0.006
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0148 0.038 0.038
Brugia malayi hypothetical protein 0.0087 0.009 0.0074
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0125 0.027 0.027
Echinococcus granulosus NCK adaptor protein 0.0099 0.0148 0.0148
Giardia lamblia Kinase, AGC PKA 0.0113 0.0212 0.1488
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0083 0.0071 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0459 0.0453
Schistosoma mansoni tyrosine kinase 0.2141 0.9948 1
Echinococcus multilocularis casein kinase I delta 0.0108 0.0191 0.0191
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0157 0.0423 0.343
Trichomonas vaginalis CMGC family protein kinase 0.01 0.015 0.0851
Echinococcus multilocularis rho associated protein kinase 0.0326 0.1238 0.1238
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0145 0.0366 0.0366
Entamoeba histolytica PH domain containing protein kinase, putative 0.0166 0.0466 0.3051
Brugia malayi p70 ribosomal S6 kinase beta 0.0292 0.1076 0.1067
Brugia malayi casein kinase 1, delta 0.0108 0.0191 0.0176
Echinococcus multilocularis 0.0507 0.2107 0.2107
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0253 0.0884 0.0884
Entamoeba histolytica casein kinase 1, putative 0.0108 0.0191 0.1218
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0145 0.0369 0.8538
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0396 0.1571 0.1571
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0145 0.0369 0.2405
Brugia malayi Protein kinase domain containing protein 0.0306 0.1141 0.1132
Entamoeba histolytica p21-activated kinase 0.0094 0.0125 0.0777
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0151 0.0395 0.0387
Brugia malayi probable protein kinase 0.018 0.0534 0.0521
Plasmodium falciparum glycogen synthase kinase 3 0.0128 0.0288 0.6303
Loa Loa (eye worm) hypothetical protein 0.0195 0.0608 0.0601
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0253 0.0884 0.0884
Loa Loa (eye worm) hypothetical protein 0.012 0.0247 0.0238
Schistosoma mansoni protein kinase 0.018 0.0534 0.0529
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Echinococcus granulosus mitogen activated protein kinase 0.0083 0.0071 0.0071
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0212 0.1488
Echinococcus granulosus dual specificity 0.0085 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.0085 0.0082 0.0487
Echinococcus multilocularis Glutaredoxin protein 5 0.0125 0.027 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0899 0.0896
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0277 0.0268
Loa Loa (eye worm) hypothetical protein 0.0095 0.0128 0.0118
Entamoeba histolytica protein kinase, putative 0.0301 0.1119 0.74
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0193 0.0596 0.0596
Leishmania major protein kinase, putative 0.01 0.0154 0.0882
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0264 0.094 0.094
Giardia lamblia Kinase, CMGC GSK 0.0128 0.0288 0.2266
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0154 0.0154
Plasmodium falciparum casein kinase 1 0.0108 0.0191 0.3656
Echinococcus granulosus expressed protein 0.0082 0.0068 0.0068
Echinococcus multilocularis expressed protein 0.0082 0.0068 0.0068
Echinococcus granulosus tyrosine protein kinase Src42A 0.0282 0.1025 0.1025
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.015 0.015
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0128 0.0288 0.0281
Giardia lamblia Kinase, NEK 0.0136 0.0324 0.2637
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0078 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.014 0.0343 0.0335
Loa Loa (eye worm) TK/EPH protein kinase 0.0147 0.0376 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.024 0.0233
Leishmania major casein kinase II, putative 0.01 0.015 0.0846
Trichomonas vaginalis AGC family protein kinase 0.0301 0.1119 1
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0354 0.137 0.5617
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.01 0.0154 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0098 0.009
Plasmodium vivax tyrosine kinase-like protein, putative 0.008 0.0058 0.0078
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0083 0.0071 0.033
Brugia malayi P38 map kinase family protein 2 0.0159 0.0435 0.0422
Schistosoma mansoni tyrosine kinase 0.1278 0.5805 0.5832
Plasmodium falciparum protein kinase 5 0.0118 0.024 0.4998
Schistosoma mansoni serine/threonine protein kinase 0.0479 0.1971 0.1975
Plasmodium falciparum protein serine/threonine kinase-1 0.0154 0.0409 0.9605
Brugia malayi serine/threonine kinase 12 0.0145 0.0369 0.0355
Plasmodium falciparum calcium-dependent protein kinase 2 0.01 0.0154 0.2623
Echinococcus multilocularis activated cdc42 kinase 1 0.1203 0.5444 0.5444
Entamoeba histolytica protein kinase domain containing protein 0.0203 0.0645 0.4245
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0157 0.0423 0.3846
Onchocerca volvulus 0.0108 0.0191 0.0762
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.104 0.9255
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0136 0.0324 0.7312
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0098 0.0362
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0154 0.0409 0.3244
Entamoeba histolytica protein kinase , putative 0.0145 0.0369 0.2405
Loa Loa (eye worm) casein kinase 0.0182 0.0543 0.0536
Entamoeba histolytica protein kinase, putative 0.0145 0.0369 0.2405
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0084 0.0075 0.0374
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.015 0.2585
Trypanosoma cruzi casein kinase, putative 0.0108 0.0191 0.1532
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0115 0.0222 0.0222
Brugia malayi Doublecortin family protein 0.0151 0.0395 0.0381
Giardia lamblia Kinase, PLK 0.0285 0.104 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0093 0.0121 0.0747
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0084 0.0075 0.0067
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.024 0.024
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.01 0.0154 0.0942
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0084 0.0075 0.0374
Echinococcus granulosus tyrosine protein kinase Blk 0.0244 0.0844 0.0844
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0145 0.0366 0.0366
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0087 0.009 0.009
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0354 0.137 0.137

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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