Detailed information for compound 1515758

Basic information

Technical information
  • TDR Targets ID: 1515758
  • Name: [2-[2-[(4-methylphenyl)amino]-2-oxoethyl]-1,3 -thiazol-4-yl]methyl (2S)-2-[(2-ethoxybenzoyl )amino]-3-methylbutanoate
  • MW: 509.617 | Formula: C27H31N3O5S
  • H donors: 2 H acceptors: 4 LogP: 4.56 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOc1ccccc1C(=O)N[C@H](C(=O)OCc1csc(n1)CC(=O)Nc1ccc(cc1)C)C(C)C
  • InChi: 1S/C27H31N3O5S/c1-5-34-22-9-7-6-8-21(22)26(32)30-25(17(2)3)27(33)35-15-20-16-36-24(29-20)14-23(31)28-19-12-10-18(4)11-13-19/h6-13,16-17,25H,5,14-15H2,1-4H3,(H,28,31)(H,30,32)/t25-/m0/s1
  • InChiKey: ZWDVJQNYEYPQIM-VWLOTQADSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-[2-[(4-methylphenyl)amino]-2-oxo-ethyl]thiazol-4-yl]methyl (2S)-2-[(2-ethoxybenzoyl)amino]-3-methyl-butanoate
  • (2S)-2-[[(2-ethoxyphenyl)-oxomethyl]amino]-3-methylbutanoic acid [2-[2-[(4-methylphenyl)amino]-2-oxoethyl]-4-thiazolyl]methyl ester
  • (2S)-2-[(2-ethoxybenzoyl)amino]-3-methyl-butyric acid [2-[2-keto-2-[(4-methylphenyl)amino]ethyl]thiazol-4-yl]methyl ester
  • [2-[2-[(4-methylphenyl)amino]-2-oxo-ethyl]-1,3-thiazol-4-yl]methyl (2S)-2-[(2-ethoxyphenyl)carbonylamino]-3-methyl-butanoate
  • T5317467

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax multidrug resistance protein 1, putative 0.0033 0.0076 0.1494
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0055 0.0094
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0428 0.0906
Onchocerca volvulus 0.003 0.0058 0.0125
Leishmania major calpain family cysteine protease-like protein 0.0026 0.0032 0.005
Schistosoma mansoni calpain (C02 family) 0.0087 0.0395 0.0395
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0058 0.0101
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0044 0.0071
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Entamoeba histolytica P-glyco protein 6, putative 0.0033 0.0076 0.1713
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0633 0.3666 0.7952
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0315 0.0661
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.041 0.089
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.0036 0.0036
Plasmodium vivax vivapain-2 0.0027 0.0036 0.0564
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0036 0.0036
Entamoeba histolytica P-glycoprotein 5, putative 0.0033 0.0076 0.1713
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0023 0.0023
Loa Loa (eye worm) fibroinase 0.0027 0.0036 0.0036
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Schistosoma mansoni hypothetical protein 0.0023 0.0012 0.0012
Onchocerca volvulus Cathepsin F homolog 0.0027 0.0036 0.0078
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Entamoeba histolytica calpain family cysteine protease, putative 0.0026 0.0032 0.0714
Brugia malayi KE2 family protein 0.0064 0.0258 0.0258
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0058 0.0101
Onchocerca volvulus 0.0035 0.0085 0.0184
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0076 0.0586
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0296 0.0296
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0236 0.0236
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0058 0.0125
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0181 0.0369
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0052 0.0188 0.0446
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0058 0.0058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0085 0.0424
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.008 0.0148
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0027 0.0036 0.0626
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0011 0.0257
Onchocerca volvulus 0.0035 0.0085 0.0184
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0012 0.0001
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0114 0.2572
Schistosoma mansoni hypothetical protein 0.0026 0.0032 0.0032
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0085 0.0653
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Plasmodium falciparum calpain 0.0026 0.0032 0.0532
Brugia malayi nuclear receptor NHR-88 0.003 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0033 0.0076 0.014
Plasmodium vivax subtilisin-like serine protease, putative 0.0052 0.0188 0.4089
Loa Loa (eye worm) hypothetical protein 0.0204 0.1097 0.1097
Loa Loa (eye worm) hypothetical protein 0.0095 0.0444 0.0444
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0469 0.0469
Brugia malayi PHD-finger family protein 0.0028 0.0044 0.0044
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Loa Loa (eye worm) hypothetical protein 0.0063 0.0251 0.0251
Loa Loa (eye worm) fli-1 protein 0.0223 0.1211 0.1211
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0294 0.1634 0.3534
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.008 0.008
Trypanosoma brucei calpain-like protein, putative 0.0087 0.0395 0.0835
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0032 0.0244
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0032 0.0244
Mycobacterium ulcerans lipase LipD 0.0035 0.0085 0.0424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0058 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0058 0.0125
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0188 0.1451
Schistosoma mansoni calpain-7 (C02 family) 0.009 0.0413 0.0413
Onchocerca volvulus Cathepsin L homolog 0.0027 0.0036 0.0078
Mycobacterium ulcerans hypothetical protein 0.0035 0.0085 0.0424
Onchocerca volvulus Cathepsin L homolog 0.0027 0.0036 0.0078
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0702 0.1503
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0227 0.0227
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0085 0.0653
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0055 0.0055
Brugia malayi Ets-domain containing protein 0.0073 0.0315 0.0315
Entamoeba histolytica protein kinase, putative 0.0061 0.0239 0.5385
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0087 0.0395 0.0841
Plasmodium vivax hypothetical protein, conserved 0.0095 0.0444 1
Schistosoma mansoni nuclear hormone receptor 0.003 0.0058 0.0058
Entamoeba histolytica P-glycoprotein-1 0.0033 0.0076 0.1713
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0032 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0012 0.0007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0058 0.0058
Brugia malayi beta-lactamase family protein 0.0035 0.0085 0.0085
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0044 0.0071
Trypanosoma brucei C-8 sterol isomerase, putative 0.0365 0.2059 0.4455
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.1124 0.1124
Echinococcus multilocularis cathepsin b 0.0294 0.1634 0.353
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0058 0.0058
Schistosoma mansoni furin-1 (S08 family) 0.0052 0.0188 0.0188
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0052 0.0188 0.0188
Onchocerca volvulus 0.0143 0.0733 0.1592
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0048 0.0104
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.011 0.0215
Leishmania major calpain protease-like protein 0.0026 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.079 0.4608 0.4608
Schistosoma mansoni Smad4 0.0025 0.0023 0.0023
Echinococcus multilocularis smad 0.0025 0.0023 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0114 0.023
Trichomonas vaginalis hypothetical protein 0.0026 0.0032 0.0244
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0052 0.0188 0.0999
Loa Loa (eye worm) hypothetical protein 0.0365 0.2059 0.2059
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0032 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Brugia malayi calpain family protein 1 0.023 0.1253 0.1253
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.079 0.4608 1
Loa Loa (eye worm) beta-lactamase 0.0035 0.0085 0.0085
Plasmodium falciparum prefoldin subunit 6, putative 0.0064 0.0258 0.5741
Toxoplasma gondii cathepsin B 0.0099 0.0469 0.0996
Echinococcus multilocularis caspase 2 0.0065 0.0266 0.0555
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0058 0.0101
Loa Loa (eye worm) Smad1 0.0025 0.0023 0.0023
Mycobacterium tuberculosis Probable peptidase 0.0322 0.1806 0.4458
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0702 0.1508
Entamoeba histolytica P-glycoprotein-2 0.0033 0.0076 0.1713
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0058 0.0101
Brugia malayi celfurPC protein 0.0052 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0041 0.0122 0.0122
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0011 0.0006
Echinococcus granulosus furin 0.0052 0.0188 0.0408
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0052 0.0188 0.0446
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0036
Trichomonas vaginalis calpain, putative 0.0026 0.0032 0.0244
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0254 0.1398 0.3035
Brugia malayi Cathepsin L-like precursor 0.0027 0.0036 0.0036
Trypanosoma cruzi subtilisin peptidase 0.0052 0.0188 0.039
Brugia malayi prolyl oligopeptidase family protein 0.0095 0.0444 0.0444
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0076 0.0586
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0052 0.0188 0.0384
Toxoplasma gondii subtilisin SUB9 0.0052 0.0188 0.0384
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.008 0.008
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0087 0.0395 0.0835
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0015 0.0119
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0033 0.0076 0.0076
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0114 0.023
Loa Loa (eye worm) hypothetical protein 0.0064 0.0258 0.0258
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0087 0.0395 0.0841
Loa Loa (eye worm) prolyl oligopeptidase 0.0095 0.0444 0.0444
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.041 0.041
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0052 0.0188 0.0999
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0428 0.0928
Brugia malayi hypothetical protein 0.0033 0.0073 0.0073
Brugia malayi Kringle domain containing protein 0.0023 0.0012 0.0012
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0445 0.0445
Echinococcus multilocularis cathepsin L cysteine protease 0.0027 0.0036 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0036 0.0059
Mycobacterium tuberculosis Conserved protein 0.0035 0.0085 0.0189
Brugia malayi Ets-domain containing protein 0.0073 0.0315 0.0315
Giardia lamblia Alanyl dipeptidyl peptidase 0.0095 0.0444 0.9443
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0085 0.0085
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Echinococcus granulosus smad 0.0025 0.0023 0.0049
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0085 0.0189
Echinococcus granulosus apoptotic protease activating factor 1 0.0065 0.0266 0.0578
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0181 0.0369
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0227 0.0468
Trypanosoma cruzi kinesin, putative 0.0061 0.0239 0.0501
Trypanosoma brucei hypothetical protein 0.0026 0.0032 0.0044
Brugia malayi steroid hormone receptor 0.003 0.0058 0.0058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0294 0.1634 0.1634
Onchocerca volvulus 0.0035 0.0085 0.0184
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0015 0.0033
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0138 0.0704 0.1507
Plasmodium falciparum cysteine proteinase falcipain 3 0.0027 0.0036 0.0626
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0011 0.0025
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0015 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0055 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Schistosoma mansoni multidrug resistance protein 0.0033 0.0076 0.0076
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0044 0.0756
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0036 0.0806
Echinococcus multilocularis calpain 5 0.0087 0.0395 0.0835
Brugia malayi calpain D 0.0026 0.0032 0.0032
Echinococcus multilocularis apoptotic protease activating factor 1 0.0065 0.0266 0.0555
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0166
Brugia malayi neuroendocrine convertase 1 precursor 0.0052 0.0188 0.0188
Loa Loa (eye worm) cysteine protease 0.0027 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Trypanosoma cruzi prefoldin subunit, putative 0.0064 0.0258 0.0543
Giardia lamblia Hypothetical protein 0.0064 0.0258 0.5394
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0188 0.1451
Onchocerca volvulus 0.0027 0.0036 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.0076 0.0586
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0058 0.0058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Trichomonas vaginalis esterase, putative 0.0035 0.0085 0.0653
Trypanosoma brucei oligopeptidase b 0.0322 0.1806 0.3904
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0058 0.0058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Entamoeba histolytica prolyl oligopeptidase family protein 0.0095 0.0444 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0114 0.0587
Echinococcus multilocularis 0.0052 0.0188 0.0384
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0015 0.0033
Echinococcus granulosus neuroendocrine convertase 2 0.0052 0.0188 0.0408
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0076 0.0165
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0188 0.1451
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0114 0.0223
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0058 0.0125
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1213 0.2987
Brugia malayi jmjC domain containing protein 0.0092 0.0428 0.0428
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Giardia lamblia PHD finger protein 15 0.0028 0.0044 0.0714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0058 0.0058
Toxoplasma gondii prefoldin subunit 6, putative 0.0064 0.0258 0.0537
Echinococcus granulosus prefoldin subunit 6 0.0064 0.0258 0.0561
Leishmania major cathepsin L-like protease 0.0027 0.0036 0.0059
Toxoplasma gondii subtilisin SUB7 0.0052 0.0188 0.0384
Trypanosoma cruzi cruzipain precursor, putative 0.0078 0.034 0.072
Schistosoma mansoni hypothetical protein 0.0028 0.0044 0.0044
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0122 0.0122
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0095 0.0444 0.0444
Echinococcus multilocularis cysteine protease 0.0027 0.0036 0.0053
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.0469 0.1001
Mycobacterium ulcerans beta-lactamase 0.0035 0.0085 0.0424
Trypanosoma cruzi oligopeptidase b 0.0322 0.1806 0.3908
Echinococcus multilocularis geminin 0.0677 0.393 0.8526
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.0076 0.0586
Echinococcus granulosus Dipeptidyl peptidase 9 0.0138 0.0704 0.1528
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0085 0.0653
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0058 0.0058
Brugia malayi Smad1 0.0025 0.0023 0.0023
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0085 0.0189
Giardia lamblia Cathepsin B precursor 0.0099 0.0469 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0026 0.0032 0.0044
Plasmodium falciparum subtilisin-like protease 1 0.0052 0.0188 0.4128
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0076 0.0165
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.034 0.072
Entamoeba histolytica prefoldin subunit 6, putative 0.0064 0.0258 0.5823
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0076 0.0165
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Schistosoma mansoni multidrug resistance protein 0.0033 0.0076 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0032 0.0244
Loa Loa (eye worm) calpain 5 0.0061 0.0239 0.0239
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Echinococcus granulosus inhibitor of apoptosis protein 0.0254 0.1398 0.3035
Loa Loa (eye worm) endoprotease bli-4 0.0052 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0322 0.1806 0.3908
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Echinococcus multilocularis prefoldin subunit 6 0.0064 0.0258 0.0537
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Onchocerca volvulus 0.0027 0.0036 0.0078
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0254 0.1398 0.1398
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0796 0.1953
Echinococcus granulosus cathepsin L cysteine proteinase 0.0027 0.0036 0.0078
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0058 0.0058
Loa Loa (eye worm) prolyl oligopeptidase 0.0251 0.1376 0.1376
Leishmania major cathepsin L-like protease 0.0027 0.0036 0.0059
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0294 0.1634 0.1634
Loa Loa (eye worm) hypothetical protein 0.0186 0.0991 0.0991
Schistosoma mansoni survival motor neuron protein 0.0095 0.0445 0.0445
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0058 0.0125
Echinococcus multilocularis survival motor neuron protein 1 0.0466 0.2668 0.5781
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0027 0.0036 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0055 0.0055
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0058 0.0058
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0026 0.0032 0.0044
Plasmodium vivax vivapain-2 0.0027 0.0036 0.0564
Echinococcus granulosus peregrin 0.0028 0.0044 0.0096
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Trypanosoma brucei cysteine peptidase C (CPC) 0.0099 0.0469 0.0996
Loa Loa (eye worm) MH2 domain-containing protein 0.0361 0.2037 0.2037
Brugia malayi MH1 domain containing protein 0.0025 0.0023 0.0023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0085 0.0085
Echinococcus multilocularis membrane bound transcription factor site 1 0.0052 0.0188 0.0384
Trypanosoma brucei calpain, putative 0.0026 0.0032 0.0044
Trypanosoma cruzi conserved protein 0.0026 0.0032 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0058 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Trypanosoma cruzi prolyl endopeptidase 0.079 0.4608 1
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0076 0.0586
Echinococcus granulosus FTZ F1 alpha 0.003 0.0058 0.0125
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0227 0.1214
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.079 0.4608 0.4608
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Entamoeba histolytica P-glycoprotein-2, putative 0.0033 0.0076 0.1713
Brugia malayi Pre-SET motif family protein 0.003 0.0055 0.0055
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0296 0.0642
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0044 0.0071
Loa Loa (eye worm) inositol-1 0.004 0.0114 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.041 0.041
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0012 0.0001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0027 0.0036 0.0053
Onchocerca volvulus Alhambra homolog 0.0028 0.0044 0.0096
Leishmania major hypothetical protein, conserved 0.0035 0.0085 0.0166
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0181 0.3965
Leishmania major hypothetical protein, conserved 0.0023 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0065 0.0266 0.0266
Toxoplasma gondii hypothetical protein 0.0095 0.0444 0.094
Echinococcus granulosus membrane bound transcription factor site 1 0.0052 0.0188 0.0408
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0012 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0444 0.3421
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0258 0.1992
Entamoeba histolytica hypothetical protein, conserved 0.0095 0.0444 1
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0076 0.0165
Brugia malayi jmjC domain containing protein 0.0034 0.008 0.008
Onchocerca volvulus 0.0027 0.0036 0.0078
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0027 0.0036 0.0626
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0702 0.1508
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0227 0.0474
Loa Loa (eye worm) hypothetical protein 0.0065 0.0266 0.0266
Trichomonas vaginalis abcb9, putative 0.0033 0.0076 0.0586
Entamoeba histolytica hypothetical protein 0.007 0.0296 0.6671
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Toxoplasma gondii hypothetical protein 0.0026 0.0032 0.0044
Toxoplasma gondii ABC1 family protein 0.0035 0.0085 0.0159
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0032 0.0044
Leishmania major oligopeptidase b 0.0322 0.1806 0.3908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0076 0.014
Plasmodium vivax prefoldin subunit 6, putative 0.0064 0.0258 0.5713
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0023 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.041 0.089
Echinococcus granulosus survival motor neuron protein 1 0.0466 0.2668 0.5791
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0033 0.0076 0.014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0236 0.0236
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0085 0.0159
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0087 0.0395 0.0841
Leishmania major prefoldin subunit, putative 0.0064 0.0258 0.0543
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0032 0.0244
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0138 0.0704 0.1512
Entamoeba histolytica calpain large subunit domain III containing protein 0.0061 0.0239 0.5385
Brugia malayi proprotein convertase 2 0.0052 0.0188 0.0188
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0227 0.1214
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Schistosoma mansoni inositol monophosphatase 0.004 0.0114 0.0114
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0072 0.0304 0.0643
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0012 0.0012
Leishmania major subtilisin-like serine peptidase 0.0052 0.0188 0.039
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0138 0.0704 0.1507
Echinococcus granulosus calpain 7 C02 family 0.0087 0.0395 0.0858
Schistosoma mansoni smad1 5 8 and 0.0025 0.0023 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0181 0.0375
Toxoplasma gondii subtilisin SUB12 0.0067 0.0276 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0027 0.0036 0.0276
Toxoplasma gondii cathepsin CPL 0.0027 0.0036 0.0053
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0012 0.0027
Echinococcus multilocularis cathepsin b 0.0294 0.1634 0.353
Brugia malayi Cathepsin L-like precursor 0.0027 0.0036 0.0036
Toxoplasma gondii subtilisin SUB6 0.0052 0.0188 0.0384
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Trichomonas vaginalis abcb9, putative 0.0033 0.0076 0.0586
Brugia malayi Cell death protein 3 precursor 0.0065 0.0266 0.0266
Toxoplasma gondii subtilisin SUB4 0.0052 0.0188 0.0384
Entamoeba histolytica hypothetical protein 0.007 0.0296 0.6671
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0254 0.1398 0.1398
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.003 0.0055 0.0055
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0058 0.0125
Toxoplasma gondii subtilisin SUB2 0.0052 0.0188 0.0384
Echinococcus granulosus prolyl endopeptidase 0.079 0.4608 1
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0227 0.0227
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0052 0.0188 0.0999
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0058 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0055 0.0055
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0052 0.0188 0.0188
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0251 0.1376 0.2987
Loa Loa (eye worm) transcription factor SMAD2 0.0361 0.2037 0.2037
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0058 0.0125
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0095 0.0444 0.3421
Brugia malayi ABC transporter family protein 0.0033 0.0076 0.0076
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0121 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0058 0.0058
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0089 0.02
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0076 0.0165
Loa Loa (eye worm) hypothetical protein 0.0095 0.0444 0.0444
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0032 0.005
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0314 0.0314
Toxoplasma gondii prolyl endopeptidase 0.079 0.4608 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0058 0.0125
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0012 0.0012
Schistosoma mansoni thyroid hormone receptor 0.003 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0227 0.0541
Echinococcus multilocularis Smad4 0.0025 0.0023 0.0025
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0138 0.0704 0.0704
Onchocerca volvulus Deterin homolog 0.0254 0.1398 0.3035
Toxoplasma gondii subtilisin SUB10 0.0052 0.0188 0.0384
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0095 0.0444 0.3421
Plasmodium falciparum phd finger protein, putative 0.0028 0.0044 0.0817
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Onchocerca volvulus 0.003 0.0055 0.0118
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0052 0.0188 0.0408
Brugia malayi hypothetical protein 0.007 0.0296 0.0296
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.034 0.072
Echinococcus granulosus calpain 0.0087 0.0395 0.0858
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.041 0.0867
Loa Loa (eye worm) calpain 0.0087 0.0395 0.0395
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0055 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0027 0.0036 0.0276
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0058 0.0101
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis calpain, putative 0.0026 0.0032 0.0244
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0175 0.0362
Onchocerca volvulus Prolyl endopeptidase homolog 0.079 0.4608 1
Trypanosoma cruzi hypothetical protein, conserved 0.0095 0.0444 0.0946
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Loa Loa (eye worm) hypothetical protein 0.0052 0.0188 0.0188
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0052 0.0188 0.039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Onchocerca volvulus 0.0065 0.0266 0.0578
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0052 0.0188 0.0446
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0085 0.1696
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0058 0.0058
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0085 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0027 0.0036 0.0053
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0055 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0099 0.0469 0.1001
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0058 0.0125
Schistosoma mansoni smad1 5 8 and 0.0025 0.0023 0.0023
Echinococcus granulosus cathepsin b 0.0294 0.1634 0.3546
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0224 0.0224
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.1623 0.3509
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0011 0.0007
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0181 0.3925
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0058 0.0058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Brugia malayi beta-lactamase family protein 0.0035 0.0085 0.0085
Brugia malayi Inositol-1 0.004 0.0114 0.0114
Brugia malayi calpain family protein 1 0.023 0.1253 0.1253
Trypanosoma cruzi oligopeptidase b 0.0322 0.1806 0.3908
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.0036 0.0036
Entamoeba histolytica cysteine protease, putative 0.0027 0.0036 0.0806
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0254 0.1398 0.3017
Schistosoma mansoni hypothetical protein 0.0023 0.0012 0.0012
Trypanosoma brucei prolyl oligopeptidase, putative 0.0322 0.1806 0.3904
Toxoplasma gondii subtilisin SUB1 0.0052 0.0188 0.0384
Loa Loa (eye worm) hypothetical protein 0.0051 0.0181 0.0181
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0055 0.0055
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0296 0.0619
Brugia malayi Protein kinase domain containing protein 0.0023 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0085 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Giardia lamblia Cathepsin B precursor 0.0099 0.0469 1
Leishmania major C-8 sterol isomerase-like protein 0.0365 0.2059 0.4458
Brugia malayi endoprotease bli-4 precursor 0.0052 0.0188 0.0188
Onchocerca volvulus 0.0027 0.0036 0.0078
Schistosoma mansoni ap endonuclease 0.0023 0.0011 0.0011
Schistosoma mansoni Mername-AA248 (C02 family) 0.0087 0.0395 0.0395
Giardia lamblia Alanyl dipeptidyl peptidase 0.0095 0.0444 0.9443
Brugia malayi calpain 5 0.0026 0.0032 0.0032
Brugia malayi MH1 domain containing protein 0.0025 0.0023 0.0023
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0023 0.0023
Echinococcus multilocularis acylamino acid releasing enzyme 0.0095 0.0444 0.094
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0032 0.005
Brugia malayi Bromodomain containing protein 0.0028 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.023 0.1253 0.1253
Loa Loa (eye worm) proprotein convertase 2 0.0052 0.0188 0.0188
Schistosoma mansoni smad 0.0025 0.0023 0.0023
Plasmodium falciparum multidrug resistance protein 1 0.0033 0.0076 0.155
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0254 0.1398 0.1398
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Plasmodium vivax calpain, putative 0.0087 0.0395 0.8879
Entamoeba histolytica prolyl oligopeptidase family protein 0.0095 0.0444 1
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0114 0.0223
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.041 0.041
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.0076 0.014
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0322 0.1806 0.3908
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0076 0.0165
Trypanosoma cruzi prefoldin subunit, putative 0.0064 0.0258 0.0543
Mycobacterium tuberculosis Conserved protein 0.0035 0.0085 0.0189
Trypanosoma brucei Calpain-like protein 2 0.0026 0.0032 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0188 0.1451
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0058 0.0058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0032 0.005
Echinococcus granulosus jumonji domain containing protein 0.0039 0.011 0.0239
Loa Loa (eye worm) calpain D 0.0026 0.0032 0.0032
Schistosoma mansoni caspase-7 (C14 family) 0.0065 0.0266 0.0266
Loa Loa (eye worm) calpain family protein 1 0.023 0.1253 0.1253
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0365 0.2059 0.4458
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0085 0.0653
Echinococcus granulosus cathepsin l1 0.0027 0.0036 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0835
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0011 0.0016
Trypanosoma brucei Calpain-like protein 1.1 0.0026 0.0032 0.0044
Schistosoma mansoni hypothetical protein 0.0677 0.393 0.393
Loa Loa (eye worm) cathepsin B 0.0099 0.0469 0.0469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Trypanosoma cruzi major cysteine proteinase, putative 0.0063 0.0252 0.0528
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0044 0.0096
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0322 0.1806 0.3908
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0138 0.0704 0.1507
Echinococcus granulosus calpain 5 0.0087 0.0395 0.0858
Loa Loa (eye worm) hypothetical protein 0.0466 0.2668 0.2668
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Echinococcus multilocularis neuroendocrine convertase 2 0.0052 0.0188 0.0384
Onchocerca volvulus Cell death protein 3 homolog 0.0065 0.0266 0.0578
Plasmodium falciparum peptidase, putative 0.0095 0.0444 1
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0114 0.0248
Echinococcus granulosus Smad4 0.0025 0.0023 0.0049
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0023 0.0025
Echinococcus multilocularis cysteine protease 0.0027 0.0036 0.0053
Leishmania major cathepsin L-like protease 0.0027 0.0036 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0188 0.1451
Brugia malayi prolyl oligopeptidase family protein 0.079 0.4608 0.4608
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Entamoeba histolytica P-glycoprotein-5 0.0033 0.0076 0.1713
Plasmodium vivax subtilisin-like protease 2, putative 0.0052 0.0188 0.4089
Echinococcus multilocularis Furin 1 0.0052 0.0188 0.0384
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0052 0.0188 0.0188
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0181 0.3965
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Schistosoma mansoni hypothetical protein 0.0064 0.0258 0.0258
Brugia malayi prolyl oligopeptidase family protein 0.0095 0.0444 0.0444
Onchocerca volvulus 0.0027 0.0036 0.0078
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0089 0.0025
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0011 0.0006
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0052 0.0188 0.0601
Brugia malayi hypothetical protein 0.0051 0.0181 0.0181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0365 0.2059 0.2059
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0294 0.1634 0.1634
Onchocerca volvulus 0.0237 0.1297 0.2814
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0012 0.0078
Schistosoma mansoni smdr2 0.0033 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Toxoplasma gondii subtilisin SUB11 0.0052 0.0188 0.0384
Echinococcus granulosus acylamino acid releasing enzyme 0.0095 0.0444 0.0963
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0058 0.0101
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0032 0.005
Brugia malayi calpain 7 0.0087 0.0395 0.0395
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0085 0.0085
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0236 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0138 0.0704 0.1507
Schistosoma mansoni hypothetical protein 0.0677 0.393 0.393
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Echinococcus granulosus calpain A 0.0244 0.1338 0.2905
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0138 0.0704 0.1512
Brugia malayi Cathepsin L-like precursor 0.0027 0.0036 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.0044
Leishmania major hypothetical protein, conserved 0.0026 0.0032 0.005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.008 0.008
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0114 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0114 0.023
Plasmodium falciparum subtilisin-like protease 2 0.0052 0.0188 0.4128
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0033 0.0076 0.5
Schistosoma mansoni calpain C (C02 family) 0.0087 0.0395 0.0395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0076 0.0165
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0023 0.0023
Mycobacterium leprae Possible secreted protease 0.0052 0.0188 0.0601
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0085 0.0189
Leishmania major kinesin, putative 0.0061 0.0239 0.0501
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Trypanosoma brucei calpain-like protein, putative 0.0087 0.0395 0.0835
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0044 0.0044
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0121 0.0245
Echinococcus multilocularis inhibitor of apoptosis protein 0.0254 0.1398 0.3017
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0121 0.0245
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0032 0.005
Brugia malayi prolyl oligopeptidase family protein 0.0138 0.0704 0.0704
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0052 0.0188 0.039
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0052 0.0188 0.0384
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0095 0.0444 0.0946
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0322 0.1806 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0023 0.0049
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0033 0.0076 0.0147
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Echinococcus multilocularis hypothetical protein 0.0087 0.0395 0.0835
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0058 0.0058
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0011 0.0088
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0052 0.0188 0.0446
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Leishmania major p-glycoprotein 0.0033 0.0076 0.0147
Schistosoma mansoni hypothetical protein 0.0065 0.0266 0.0266
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0036 0.0806
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0076 0.014
Leishmania major hypothetical protein, conserved 0.0051 0.0181 0.0375
Echinococcus multilocularis calpain family protein 1, d 0.0169 0.089 0.1911
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.079 0.4608 0.4608
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0058 0.0101
Plasmodium vivax subtilisin-like protease 1 0.0052 0.0188 0.4089
Trypanosoma brucei Calpain-like protein CALP1.3 0.0026 0.0032 0.0044
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.0076 0.014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0032 0.005
Plasmodium vivax SET domain protein, putative 0.003 0.0055 0.0998
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0032 0.0244
Trypanosoma brucei subtilisin peptidase 0.0052 0.0188 0.0384
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.008 0.0173
Echinococcus granulosus Furin 1 0.0052 0.0188 0.0408
Leishmania major cysteine peptidase A (CPA) 0.0027 0.0036 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.041 0.041
Mycobacterium tuberculosis Conserved protein 0.0035 0.0085 0.0189
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0058 0.0058
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0181 0.0375
Trypanosoma brucei antigen, putative 0.0087 0.0395 0.0835
Brugia malayi Cathepsin L-like precursor 0.0027 0.0036 0.0036
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0138 0.0704 0.1512
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0322 0.1806 0.4458
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0076
Trypanosoma brucei calpain-like protein, putative 0.0087 0.0395 0.0835
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0227 0.0492
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0074
Echinococcus multilocularis cathepsin L cysteine protease 0.0027 0.0036 0.0053
Brugia malayi cathepsin B-like cysteine proteinase 0.0294 0.1634 0.1634
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0058 0.0125
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0076 0.0586
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0085 0.0159
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0254 0.1398 0.1398
Entamoeba histolytica hypothetical protein 0.007 0.0296 0.6671
Toxoplasma gondii subtilisin SUB8 0.0052 0.0188 0.0384
Loa Loa (eye worm) hypothetical protein 0.0169 0.089 0.089
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0244 0.1337 0.2901
Schistosoma mansoni gabp alpha 0.0073 0.0315 0.0315
Schistosoma mansoni thyroid hormone receptor 0.003 0.0058 0.0058
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0227 0.1214
Giardia lamblia Cathepsin B precursor 0.0099 0.0469 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0114 0.088
Leishmania major cathepsin L-like protease 0.0078 0.034 0.072
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0052 0.0188 0.039
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.0044
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0085 0.0189
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0011 0.0066
Brugia malayi MH2 domain containing protein 0.0361 0.2037 0.2037
Echinococcus multilocularis calpain 7 (C02 family) 0.0087 0.0395 0.0835
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0044 0.0044
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0076 0.014
Echinococcus granulosus caspase 2 0.0065 0.0266 0.0578
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0322 0.1806 0.3904
Entamoeba histolytica P-glycoprotein-2 0.0033 0.0076 0.1713
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0294 0.1634 0.1634
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Brugia malayi Fli-1 protein 0.0223 0.1211 0.1211
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0087 0.0395 0.0841
Brugia malayi calpain 5 0.0061 0.0239 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Leishmania major cathepsin L-like protease 0.0027 0.0036 0.0059
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0251 0.1376 0.297
Onchocerca volvulus 0.0027 0.0036 0.0078
Brugia malayi Cathepsin L-like precursor 0.0027 0.0036 0.0036
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0095 0.0444 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0087 0.0395 0.0841
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0085 0.0189
Schistosoma mansoni hypothetical protein 0.0041 0.0122 0.0122
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0087 0.0395 0.0841
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0244 0.1337 0.1337
Loa Loa (eye worm) multidrug resistance protein 3 0.0033 0.0076 0.0076
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.1623 0.3505
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0114 0.0223
Plasmodium falciparum subtilisin-like protease 3 0.0052 0.0188 0.4128
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Schistosoma mansoni ap endonuclease 0.0023 0.0011 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0058 0.0101
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0251 0.1376 0.2987
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Trichomonas vaginalis set domain proteins, putative 0.0237 0.1297 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0058 0.0058
Onchocerca volvulus 0.0023 0.0012 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0058 0.0058
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0052 0.0188 0.0188
Brugia malayi MH2 domain containing protein 0.0025 0.0023 0.0023
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0012 0.0026
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0085 0.0189
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0023 0.0049
Echinococcus multilocularis calpain 0.0087 0.0395 0.0835
Echinococcus multilocularis peregrin 0.0028 0.0044 0.0071
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0095 0.0444 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0095 0.0444 0.094
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0121 0.0239
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.006 0.0236 0.0236
Trypanosoma cruzi kinesin, putative 0.0061 0.0239 0.0501
Schistosoma mansoni calpain-7 (C02 family) 0.009 0.0413 0.0413
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0032 0.005
Schistosoma mansoni site-1 peptidase (S08 family) 0.0052 0.0188 0.0188
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0085 0.0184
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0032 0.005
Brugia malayi beta-lactamase 0.0035 0.0085 0.0085
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0026 0.0032 0.005
Onchocerca volvulus 0.0033 0.0076 0.0165
Echinococcus granulosus geminin 0.0677 0.393 0.8529
Trichomonas vaginalis calpain, putative 0.0026 0.0032 0.0244
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Loa Loa (eye worm) hypothetical protein 0.0254 0.1398 0.1398
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0469 0.3618
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0052 0.0188 0.0601
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0011 1
Schistosoma mansoni calpain-2 (C02 family) 0.0026 0.0032 0.0032
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0076 0.0586
Entamoeba histolytica prolyl oligopeptidase family protein 0.0095 0.0444 1
Brugia malayi MH2 domain containing protein 0.0025 0.0023 0.0023
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0244 0.1337 0.2884
Schistosoma mansoni inositol monophosphatase 0.004 0.0114 0.0114
Echinococcus granulosus cathepsin b 0.0294 0.1634 0.3546
Schistosoma mansoni ets-related 0.0223 0.1211 0.1211
Trypanosoma brucei prefoldin subunit, putative 0.0064 0.0258 0.0537
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.041 0.0867
Loa Loa (eye worm) hypothetical protein 0.0254 0.1398 0.1398
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0076 0.0586
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.034 0.072
Mycobacterium ulcerans hypothetical protein 0.0154 0.0796 0.438
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0322 0.1806 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0227 0.0468
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0114 0.088
Trypanosoma brucei prolyl endopeptidase 0.079 0.4608 1
Toxoplasma gondii hypothetical protein 0.0047 0.0157 0.0317
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.023 0.1253 0.1253
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0695 0.4039 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0058 0.0101
Leishmania major cathepsin L-like protease 0.0078 0.034 0.072
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0244 0.1337 0.1337
Trichomonas vaginalis abcb9, putative 0.0033 0.0076 0.0586
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0294 0.1634 0.1634
Trypanosoma brucei cysteine peptidase, putative 0.0026 0.0032 0.0044
Leishmania major hypothetical protein, unknown function 0.0026 0.0032 0.005
Onchocerca volvulus 0.0027 0.0036 0.0078
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0052 0.0188 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0166
Leishmania major cathepsin L-like protease 0.0027 0.0036 0.0059
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0011 0.0011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0076 0.0586
Brugia malayi Cathepsin L-like precursor 0.0027 0.0036 0.0036
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0095 0.0444 0.0444
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0032 0.0244
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0058
Schistosoma mansoni smad1 5 8 and 0.0025 0.0023 0.0023
Brugia malayi prolyl oligopeptidase family protein 0.0251 0.1376 0.1376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.034 0.0714
Schistosoma mansoni inhibitor of apoptosis protein 0.0254 0.1398 0.1398
Loa Loa (eye worm) hypothetical protein 0.0052 0.0188 0.0188
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0058 0.0125
Onchocerca volvulus 0.0052 0.0188 0.0408
Trypanosoma brucei calpain, putative 0.0026 0.0032 0.0044
Schistosoma mansoni hypothetical protein 0.007 0.0296 0.0296
Loa Loa (eye worm) ctsf protein 0.0027 0.0036 0.0036
Echinococcus multilocularis calpain A 0.0244 0.1338 0.2887
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0251 0.1376 0.1376
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0026 0.0032 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0036 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0058 0.0058
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0033 0.0074 0.016
Brugia malayi multidrug resistance protein 3 0.0033 0.0076 0.0076
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.041 0.041
Echinococcus granulosus cathepsin l cysteine peptidase 0.0027 0.0036 0.0078
Onchocerca volvulus 0.0095 0.0445 0.0966
Brugia malayi nuclear hormone receptor 0.003 0.0058 0.0058
Schistosoma mansoni site-1 peptidase (S08 family) 0.0052 0.0188 0.0188
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0087 0.0395 0.0841
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0633 0.3666 0.7957
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0114 0.088
Trypanosoma brucei Calpain-like protein 1.2 0.0026 0.0032 0.0044
Echinococcus granulosus calpain A 0.0087 0.0395 0.0858
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0315 0.0684
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1623 0.3509
Schistosoma mansoni coup transcription factor 0.003 0.0058 0.0058
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0085 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0085 0.0653
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0143 0.0733 0.0733
Brugia malayi ecdysteroid receptor 0.003 0.0058 0.0058
Leishmania major cathepsin L-like protease 0.0078 0.034 0.072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0058 0.0058
Trichomonas vaginalis taga, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Brugia malayi Pre-SET motif family protein 0.0209 0.1124 0.1124
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0032 0.0244
Onchocerca volvulus 0.0254 0.1398 0.3035
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0095 0.0444 0.094
Trypanosoma brucei calpain-like protein, putative 0.0087 0.0395 0.0835
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0058 0.0058
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0076 0.014
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0076 0.0586
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0058 0.0058
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0315 0.0315
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0036 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0058 0.0058
Brugia malayi hypothetical protein 0.0065 0.0266 0.0266
Echinococcus multilocularis ATP binding cassette sub family B 0.0033 0.0074 0.0136
Brugia malayi hypothetical protein 0.0466 0.2668 0.2668
Schistosoma mansoni multidrug resistance protein 0.0033 0.0076 0.0076
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0011 0.0088
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1623 0.3509
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0076 0.0076
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0076 0.014
Echinococcus multilocularis prolyl endopeptidase 0.079 0.4608 1
Entamoeba histolytica hypothetical protein 0.007 0.0296 0.6671
Toxoplasma gondii subtilisin SUB5 0.0052 0.0188 0.0384
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0033 0.0076 0.0167
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0052 0.0188 0.1451
Loa Loa (eye worm) calpain family protein 1 0.0169 0.089 0.089
Schistosoma mansoni hypothetical protein 0.0095 0.0445 0.0445
Trypanosoma brucei kinesin, putative 0.0061 0.0239 0.0495
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0011 0.0006

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0024 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.1995 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 23.0999 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 75.6863 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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