Detailed information for compound 167271

Basic information

Technical information
  • TDR Targets ID: 167271
  • Name: (2S)-6-amino-2-[[(2S)-2-amino-5-[[amino(nitra mido)methylidene]amino]pentanoyl]-methylamino ]hexanamide
  • MW: 360.413 | Formula: C13H28N8O4
  • H donors: 5 H acceptors: 4 LogP: -2.31 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)N/C(=N/CCC[C@@H](C(=O)N([C@H](C(=O)N)CCCCN)C)N)/N
  • InChi: 1S/C13H28N8O4/c1-20(10(11(16)22)6-2-3-7-14)12(23)9(15)5-4-8-18-13(17)19-21(24)25/h9-10H,2-8,14-15H2,1H3,(H2,16,22)(H3,17,18,19)/t9-,10-/m0/s1
  • InChiKey: IBZDYDRXYTXAPL-UWVGGRQHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-6-amino-2-[[(2S)-2-amino-5-[[amino(nitramido)methylene]amino]pentanoyl]-methyl-amino]hexanamide
  • (2S)-6-amino-2-[[(2S)-2-amino-5-[[amino(nitramido)methylene]amino]-1-oxopentyl]-methylamino]hexanamide
  • (2S)-6-azanyl-2-[[(2S)-2-azanyl-5-[[azanyl(nitramido)methylidene]amino]pentanoyl]-methyl-amino]hexanamide
  • (2S)-6-amino-2-[[(2S)-2-amino-5-[(amino-nitramidomethylidene)amino]pentanoyl]-methylamino]hexanamide
  • (2S)-6-amino-2-[[(2S)-2-amino-5-[(amino-nitramido-methylene)amino]pentanoyl]-methyl-amino]hexanamide
  • (2S)-6-amino-2-[[(2S)-2-amino-5-[(amino-nitramidomethylene)amino]-1-oxopentyl]-methylamino]hexanamide
  • (2S)-6-amino-2-[[(2S)-2-amino-5-[(amino-nitramido-methylidene)amino]pentanoyl]-methyl-amino]hexanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nitric oxide synthase 1 (neuronal) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus carbonic anhydrase 0.0547 0.1916 0.4069
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0027 0.0065 0.0136
Loa Loa (eye worm) PAN domain-containing protein 0.0262 0.09 0.0904
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.005 0.0049
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0221 0.0754 0.1524
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0041 0.0111 0.0235
Echinococcus granulosus slit 2 protein 0.0282 0.0971 0.206
Echinococcus multilocularis somatostatin receptor 0.0221 0.0754 0.1524
Plasmodium vivax hypothetical protein, conserved 0.0021 0.004 0.0084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Brugia malayi MH1 domain containing protein 0.0014 0.0015 0.0015
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0049 0.0143 0.0143
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0042 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Trypanosoma cruzi cdc2-related kinase 1 0.0027 0.0065 0.0136
Echinococcus granulosus serotonin receptor 0.0221 0.0754 0.16
Echinococcus granulosus peptidase Clp S14 family 0.0044 0.0124 0.0262
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0054 0.0158 0.0335
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0008 0.0015
Echinococcus granulosus cyclin dependent kinase 1 0.0027 0.0065 0.0136
Schistosoma mansoni cytochrome P450 reductase 0.0054 0.0158 0.0158
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0013 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0117 0.1303
Schistosoma mansoni tar DNA-binding protein 0.0161 0.054 0.0539
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis chromobox protein, putative 0.007 0.0217 0.2459
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0054 0.0054
Echinococcus granulosus cpg binding protein 0.0051 0.0148 0.0314
Brugia malayi Probable ClpP-like protease 0.0067 0.0207 0.0207
Brugia malayi hypothetical protein 0.0011 0.0008 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0077 0.0163
Mycobacterium tuberculosis Conserved hypothetical protein 0.0137 0.0455 0.6674
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.003 0.0075 0.0159
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Echinococcus granulosus peregrin 0.0029 0.0071 0.015
Onchocerca volvulus 0.0038 0.0102 0.0103
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0023 0.0023
Entamoeba histolytica protein kinase, putative 0.003 0.0075 0.0799
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0014 0.0029
Echinococcus granulosus neuropeptide receptor A26 0.0617 0.2165 0.4597
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0013 0.0027
Loa Loa (eye worm) PAN domain-containing protein 0.0262 0.09 0.0904
Leishmania major hypothetical protein, conserved 0.0031 0.0077 0.0163
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis tumor protein p63 0.0291 0.1003 0.2029
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Onchocerca volvulus Protein ultraspiracle homolog 0.0013 0.0014 0.0014
Giardia lamblia Kinase, CMGC GSK 0.003 0.0075 0.071
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0111 0.0235
Loa Loa (eye worm) tubulin beta-4 chain 0.0011 0.0007 0.0006
Toxoplasma gondii hypothetical protein 0.0262 0.09 0.191
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0064 0.0196 0.0414
Brugia malayi Protein cec-1. 0.0011 0.0008 0.0007
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0032 0.008 0.008
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0221 0.0754 0.0753
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0041 0.0112 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Brugia malayi jmjC domain containing protein 0.0096 0.0309 0.031
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0021 0.004 0.0084
Onchocerca volvulus 0.0023 0.005 0.005
Schistosoma mansoni tubulin subunit beta 0.0011 0.0007 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0027 0.0065 0.0065
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0111 0.0342
Echinococcus granulosus tumor protein p63 0.0291 0.1003 0.213
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0014 0.0014
Schistosoma mansoni histamine h1 receptor 0.0221 0.0754 0.0753
Schistosoma mansoni protein arginine n-methyltransferase 0.0064 0.0196 0.0195
Schistosoma mansoni amine GPCR 0.0221 0.0754 0.0753
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0266
Giardia lamblia Kinase, CMGC CDK 0.0027 0.0065 0.06
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0221 0.0754 0.1524
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0221 0.0754 0.16
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0013 0.0014 0.0014
Loa Loa (eye worm) PAN domain-containing protein 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0016
Echinococcus granulosus Tubulin beta 2C chain 0.0011 0.0007 0.0014
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.003 0.0075 0.0159
Echinococcus multilocularis Chromo domain 0.0011 0.0008 0.0014
Brugia malayi P38 map kinase family protein 2 0.0134 0.0443 0.0445
Echinococcus multilocularis g protein coupled receptor 0.0221 0.0754 0.1524
Toxoplasma gondii hypothetical protein 0.0547 0.1916 0.4069
Schistosoma mansoni biogenic amine (5HT) receptor 0.0319 0.1103 0.1102
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0547 0.1916 0.1926
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0054 0.0158 0.0488
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0014 0.0027
Schistosoma mansoni hypothetical protein 0.0171 0.0574 0.0574
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Schistosoma mansoni hypothetical protein 0.0171 0.0574 0.0574
Echinococcus multilocularis tubulin beta 1 chain 0.0011 0.0007 0.0013
Schistosoma mansoni chromobox protein 0.0011 0.0008 0.0007
Trypanosoma brucei carbonic anhydrase-like protein 0.0918 0.3237 1
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0282 0.0971 0.097
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0047 0.0477
Entamoeba histolytica protein kinase, putative 0.0055 0.0164 0.1837
Plasmodium falciparum tubulin beta chain 0.0011 0.0007 0.0014
Echinococcus multilocularis tar DNA binding protein 0.0161 0.054 0.1091
Echinococcus multilocularis carbonic anhydrase 0.0547 0.1916 0.3877
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0048 0.0137 0.029
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0221 0.0754 0.1524
Echinococcus multilocularis Tubulin beta 2C chain 0.0011 0.0007 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.0065 0.0688
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0054 0.0158 0.032
Brugia malayi Carm1-pending protein 0.0064 0.0196 0.0196
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0183 0.0183
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0077 0.0834
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Brugia malayi G-protein coupled receptor 0.0221 0.0754 0.0757
Brugia malayi chromobox protein homolog 3 0.0039 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0055 0.0161 0.0161
Leishmania major hypothetical protein, conserved 0.1331 0.4709 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0014 0.0029
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0021 0.004 0.0084
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0221 0.0754 0.1524
Echinococcus multilocularis Mastin 0.0484 0.1691 0.3422
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.004 0.0381
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0031 0.0077 0.0336
Brugia malayi Trypsin family protein 0.0484 0.1691 0.17
Onchocerca volvulus 0.0048 0.0138 0.0139
Onchocerca volvulus 0.0239 0.082 0.0824
Echinococcus multilocularis carbonic anhydrase 0.0547 0.1916 0.3877
Echinococcus multilocularis slit 2 protein 0.0282 0.0971 0.1963
Echinococcus granulosus carbonic anhydrase II 0.0918 0.3237 0.6874
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0049
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0041 0.0111 0.0235
Loa Loa (eye worm) histone methyltransferase 0.0016 0.0024 0.0023
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.004 0.0401
Echinococcus granulosus beta LACTamase domain containing family member 0.0031 0.0077 0.0163
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0014 0.0014
Echinococcus granulosus G protein coupled receptor 139 0.0221 0.0754 0.16
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0076
Loa Loa (eye worm) helicase 0.0011 0.0008 0.0007
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) TK/FAK protein kinase 0.0101 0.0327 0.0328
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Brugia malayi Calcium binding EGF domain containing protein 0.0282 0.0971 0.0975
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0484 0.1691 0.1691
Brugia malayi MH1 domain containing protein 0.0014 0.0015 0.0015
Onchocerca volvulus 0.032 0.1106 0.1112
Echinococcus granulosus tar DNA binding protein 0.0161 0.054 0.1145
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Echinococcus granulosus biogenic amine 5HT receptor 0.0319 0.1103 0.2341
Trichomonas vaginalis tubulin alpha chain, putative 0.0011 0.0007 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0046
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0032 0.008 0.0161
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0156 0.0524 0.1112
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0126 0.0266
Echinococcus granulosus neural cadherin 0.0282 0.0971 0.206
Trichomonas vaginalis set domain proteins, putative 0.0239 0.082 0.9493
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0014 0.0014
Brugia malayi Pre-SET motif family protein 0.0031 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0221 0.0754 0.0757
Brugia malayi CXXC zinc finger family protein 0.0048 0.0138 0.0139
Toxoplasma gondii hypothetical protein 0.0116 0.038 0.0805
Toxoplasma gondii hypothetical protein 0.0262 0.09 0.191
Brugia malayi RNA binding protein 0.0161 0.054 0.0542
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0023 0.0048 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0123 0.0405 0.086
Echinococcus granulosus transmembrane protease serine 3 0.0484 0.1691 0.3591
Schistosoma mansoni myosin xvIII 0.0221 0.0754 0.0753
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0221 0.0754 0.0753
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0221 0.0754 0.0753
Onchocerca volvulus 0.0038 0.0102 0.0103
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0221 0.0754 0.0757
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0057 0.0169 0.0169
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0013 0.0013 0.0026
Onchocerca volvulus 0.0221 0.0754 0.0758
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis chromobox protein 1 0.007 0.0217 0.0437
Brugia malayi ecdysteroid receptor 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Schistosoma mansoni smad1 5 8 and 0.0014 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0055 0.0164 0.0165
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0071
Brugia malayi WGR domain containing protein 0.0055 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0012
Brugia malayi Raf kinase 0.0128 0.0422 0.0424
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0046 0.0131 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0014 0.0014
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0041 0.0111 0.0342
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0221 0.0754 0.0753
Echinococcus multilocularis carbonic anhydrase 0.0547 0.1916 0.3877
Leishmania major mitochondrial DNA polymerase beta 0.026 0.0893 0.1896
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0067 0.0207 0.0438
Brugia malayi RNA recognition motif domain containing protein 0.0161 0.054 0.0542
Leishmania major p450 reductase, putative 0.0054 0.0158 0.0335
Brugia malayi GCC2 and GCC3 family protein 0.0282 0.0971 0.0975
Echinococcus granulosus biogenic amine 5HT receptor 0.0221 0.0754 0.16
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0111 0.0235
Echinococcus granulosus orexin receptor type 2 0.0221 0.0754 0.16
Toxoplasma gondii histone lysine methyltransferase SET1 0.0092 0.0296 0.0628
Trypanosoma cruzi cdc2-related kinase 3 0.0027 0.0065 0.0136
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0017 0.0036
Trypanosoma cruzi DNA repair protein, putative 0.0013 0.0013 0.0026
Onchocerca volvulus 0.0058 0.0175 0.0176
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Echinococcus multilocularis Tubulin beta 2C chain 0.0011 0.0007 0.0013
Schistosoma mansoni smad1 5 8 and 0.0014 0.0015 0.0015
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Echinococcus granulosus cyclin dependent kinase 5 0.0027 0.0065 0.0136
Schistosoma mansoni notch 0.0282 0.0971 0.097
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0054 0.0158 0.0488
Loa Loa (eye worm) Notch2 0.0282 0.0971 0.0975
Schistosoma mansoni hypothetical protein 0.0029 0.0071 0.0071
Onchocerca volvulus 0.2318 0.8225 0.8267
Echinococcus granulosus chromobox protein 1 0.007 0.0217 0.0459
Brugia malayi Cadherin domain containing protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Echinococcus granulosus tubulin beta 4A class IVa 0.0011 0.0007 0.0014
Brugia malayi Serotonin receptor 0.0221 0.0754 0.0757
Giardia lamblia Kinase, CMGC GSK 0.003 0.0075 0.071
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0076 0.0236 0.0237
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Schistosoma mansoni rab6-interacting 0.0024 0.0054 0.0053
Echinococcus multilocularis sex peptide receptor 0.0221 0.0754 0.1524
Echinococcus multilocularis mothers against decapentaplegic 5 0.0014 0.0015 0.003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0068 0.0211 0.0425
Onchocerca volvulus 0.003 0.0075 0.0076
Brugia malayi Protein kinase domain containing protein 0.0039 0.0104 0.0104
Entamoeba histolytica acyl-coA synthetase, putative 0.002 0.004 0.0381
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0134 0.0443 0.094
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0221 0.0754 0.16
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0017 0.0017
Schistosoma mansoni survival motor neuron protein 0.0042 0.0115 0.0114
Onchocerca volvulus 0.0242 0.083 0.0834
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0008 0.0007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0039 0.0107 0.0107
Brugia malayi nuclear receptor NHR-88 0.0013 0.0014 0.0014
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0011 0.0007 0.0013
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0008 0.0007
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0918 0.3237 0.6874
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0048 0.0137 0.1527
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0014 0.0027
Trypanosoma brucei poly(adp-ribose) polymerase 0.0055 0.0161 0.0496
Echinococcus multilocularis dnaJ subfamily B 0.0686 0.2412 0.4881
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0484 0.1691 0.3422
Brugia malayi CHD4 protein 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0077
Toxoplasma gondii calcium binding egf domain-containing protein 0.0268 0.0922 0.1957
Echinococcus granulosus hypothetical protein 0.0221 0.0754 0.16
Toxoplasma gondii microneme protein MIC17A 0.0262 0.09 0.191
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0077
Echinococcus multilocularis GPCR, family 2 0.0013 0.0013 0.0025
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Schistosoma mansoni polycystin 1-related 0.0024 0.0054 0.0053
Schistosoma mansoni cpg binding protein 0.0051 0.0148 0.0148
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0484 0.1691 0.1691
Plasmodium falciparum protein kinase 5 0.0027 0.0065 0.0136
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0221 0.0754 0.1524
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0008 0.0007
Echinococcus granulosus WGR domain containing protein 0.0031 0.0077 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0547 0.1916 0.1926
Schistosoma mansoni hypothetical protein 0.0024 0.0054 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0054 0.0158 0.0159
Brugia malayi hypothetical protein 0.0204 0.0692 0.0695
Echinococcus multilocularis transcription factor Dp 1 0.0033 0.0084 0.0169
Echinococcus granulosus mitogen activated protein kinase 14 0.0134 0.0443 0.094
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0221 0.0754 0.0753
Trypanosoma cruzi GMP reductase 0.0048 0.0137 0.029
Echinococcus multilocularis geminin 0.0171 0.0574 0.1161
Echinococcus granulosus poly (ADP ribose) polymerase 0.0015 0.0022 0.0045
Loa Loa (eye worm) tubulin beta-2A chain 0.0011 0.0007 0.0006
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0103 0.0334 0.0709
Brugia malayi Protein kinase domain containing protein 0.0101 0.0327 0.0328
Brugia malayi AMP-binding enzyme family protein 0.002 0.004 0.0039
Echinococcus granulosus chromobox protein 2 0.0011 0.0008 0.0015
Echinococcus granulosus CDC7 cell division cycle 7 0.0039 0.0104 0.0221
Echinococcus multilocularis neuropeptides capa receptor 0.0221 0.0754 0.1524
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) neuropeptide F receptor 0.0221 0.0754 0.0757
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0071 0.015
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0057 0.0169 0.017
Schistosoma mansoni tar DNA-binding protein 0.0161 0.054 0.0539
Brugia malayi putative neuropeptide receptor 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0028 0.0066 0.0066
Brugia malayi notch-like transmembrane receptor 0.0282 0.0971 0.0975
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0717 0.072
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Plasmodium vivax acyl-CoA synthetase, putative 0.0015 0.0021 0.0044
Trichomonas vaginalis tubulin, putative 0.0011 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0054
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0054 0.0158 0.0335
Schistosoma mansoni biogenic amine receptor 0.0221 0.0754 0.0753
Echinococcus multilocularis tissue type plasminogen activator 0.1331 0.4709 0.9529
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0156 0.0524 0.604
Onchocerca volvulus 0.0221 0.0754 0.0758
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0275 0.0947 0.0951
Echinococcus granulosus ubiquitin specific protease 41 0.0032 0.008 0.0169
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0023 0.0049 0.0272
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0103 0.0218
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.032 0.1106 0.1111
Schistosoma mansoni cell polarity protein 0.0282 0.0971 0.097
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0055 0.0164 0.0348
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0048 0.0137 0.029
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.004 0.0401
Echinococcus multilocularis fmrfamide receptor 0.0221 0.0754 0.1524
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0055 0.0161 0.0341
Echinococcus granulosus GPCR family 2 0.0013 0.0013 0.0026
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0007 0.0013
Echinococcus multilocularis mitogen activated protein kinase 14 0.0134 0.0443 0.0896
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.004 0.011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0117 0.0118
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0014 0.0015 0.0015
Echinococcus multilocularis survival motor neuron protein 1 0.0204 0.0692 0.14
Mycobacterium tuberculosis Probable hydrolase 0.0031 0.0077 0.0903
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0047 0.0477
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Echinococcus granulosus peptide allatostatin:somatostatin 0.0221 0.0754 0.16
Brugia malayi Dopamine receptor 0.0221 0.0754 0.0757
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0275 0.0947 0.0947
Echinococcus multilocularis protein jagged 1 0.0282 0.0971 0.1963
Schistosoma mansoni cpg binding protein 0.0051 0.0148 0.0148
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0097 0.0205
Onchocerca volvulus 0.0031 0.0077 0.0078
Onchocerca volvulus 0.0038 0.0102 0.0103
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0221 0.0754 0.0757
Schistosoma mansoni notch 0.0282 0.0971 0.097
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0309 0.0625
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0041 0.0111 0.1219
Entamoeba histolytica hypothetical protein 0.0062 0.0188 0.2109
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0104 0.0104
Trichomonas vaginalis sulfite reductase, putative 0.0054 0.0158 0.1781
Brugia malayi FAD binding domain containing protein 0.0054 0.0158 0.0159
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0014 0.0029
Loa Loa (eye worm) transcription factor SMAD2 0.02 0.0681 0.0683
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) TAR-binding protein 0.0161 0.054 0.0542
Giardia lamblia Kinase, CMGC CDK 0.0027 0.0065 0.06
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) CMGC/GSK protein kinase 0.003 0.0075 0.0075
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.2802 0.995 0.995
Echinococcus multilocularis lamin dm0 0.0023 0.005 0.0099
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0023 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0198 0.0672 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0008 0.0007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0014 0.0029
Toxoplasma gondii EGF family domain-containing protein 0.0282 0.0971 0.206
Echinococcus multilocularis fmrfamide receptor 0.0221 0.0754 0.1524
Echinococcus multilocularis mitogen activated protein kinase 14 0.0134 0.0443 0.0896
Echinococcus granulosus delta-like protein 1 0.0282 0.0971 0.206
Brugia malayi Fibulin-1 precursor 0.0268 0.0922 0.0926
Echinococcus granulosus somatostatin receptor 0.0221 0.0754 0.16
Loa Loa (eye worm) steroid hormone receptor 0.0013 0.0014 0.0014
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0048 0.0137 0.0277
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0077
Brugia malayi AMP-binding enzyme family protein 0.002 0.004 0.0039
Treponema pallidum fructose-bisphosphate aldolase 0.0252 0.0863 1
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Toxoplasma gondii flavodoxin domain-containing protein 0.0027 0.0062 0.013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0008 0.0023
Mycobacterium ulcerans lipase LipD 0.0031 0.0077 0.0336
Loa Loa (eye worm) beta-tubulin 0.0011 0.0007 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0014 0.0014
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0013 0.0014 0.0014
Brugia malayi flavodoxin family protein 0.0054 0.0158 0.0159
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0221 0.0754 0.0757
Mycobacterium ulcerans hypothetical protein 0.0137 0.0455 0.2596
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Echinococcus multilocularis neurogenic locus notch protein 0.0282 0.0971 0.1963
Onchocerca volvulus 0.0221 0.0754 0.0758
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0221 0.0754 0.0757
Echinococcus granulosus mitogen activated protein kinase 11 0.0134 0.0443 0.094
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.004 0.0381
Plasmodium falciparum phd finger protein, putative 0.0029 0.0071 0.015
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0014 0.0027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0032 0.008 0.0169
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0099 0.032 0.3661
Echinococcus granulosus g protein coupled receptor 0.0221 0.0754 0.16
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0134 0.0443 0.094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0013
Mycobacterium ulcerans hypothetical protein 0.0031 0.0077 0.0336
Echinococcus granulosus tachykinin peptides receptor 99D 0.0221 0.0754 0.16
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0054 0.0113
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1396 0.4942 1
Loa Loa (eye worm) DOMON domain-containing protein 0.0038 0.0102 0.0102
Entamoeba histolytica hypothetical protein 0.0062 0.0188 0.2109
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0011 0.0011
Echinococcus multilocularis serotonin receptor 0.0319 0.1103 0.2231
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0045 0.0127 0.0269
Toxoplasma gondii PAN domain-containing protein 0.0262 0.09 0.191
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0012
Brugia malayi Cadherin domain containing protein 0.0282 0.0971 0.0975
Echinococcus multilocularis neuropeptide Y receptor 0.0221 0.0754 0.1524
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0067 0.0207 0.0438
Echinococcus multilocularis mitogen activated protein kinase 11 0.0134 0.0443 0.0896
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0031 0.0077 0.0903
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0041 0.0111 0.0235
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0309 0.0655
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0032 0.008 0.0761
Schistosoma mansoni amine GPCR 0.0221 0.0754 0.0753
Schistosoma mansoni lipoxygenase 0.0024 0.0054 0.0053
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0049 0.0143 0.0302
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0024 0.0047
Echinococcus multilocularis musashi 0.0023 0.005 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Brugia malayi PHD-finger family protein 0.0029 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0014 0.0014
Schistosoma mansoni NADPH flavin oxidoreductase 0.0027 0.0063 0.0063
Echinococcus granulosus neuropeptide receptor 0.0221 0.0754 0.16
Onchocerca volvulus 0.0031 0.0077 0.0078
Echinococcus granulosus neurogenic locus protein delta 0.0282 0.0971 0.206
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Plasmodium falciparum glycogen synthase kinase 3 0.003 0.0075 0.0159
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.003 0.0075 0.0151
Onchocerca volvulus 0.0221 0.0754 0.0758
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0027 0.0065 0.0065
Giardia lamblia High cysteine protein 0.0282 0.0971 1
Brugia malayi neuropeptide F receptor 0.0221 0.0754 0.0757
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0112 0.0237
Echinococcus multilocularis beta LACTamase domain containing family member 0.0031 0.0077 0.0155
Echinococcus multilocularis neurogenic locus notch protein 0.0282 0.0971 0.1963
Giardia lamblia Rab geranylgeranyltransferase 0.0156 0.0524 0.5368
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0041 0.0111 0.0235
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0221 0.0754 0.1524
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0221 0.0754 0.0753
Echinococcus granulosus allatostatin A receptor 0.0221 0.0754 0.16
Mycobacterium ulcerans beta-lactamase 0.0031 0.0077 0.0336
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 0.1111
Echinococcus multilocularis carbonic anhydrase II 0.0918 0.3237 0.655
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0023 0.0023
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0268 0.0922 0.0926
Onchocerca volvulus 0.0484 0.1691 0.17
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0099 0.032 0.032
Schistosoma mansoni lipoxygenase 0.0068 0.0211 0.021
Schistosoma mansoni neuropeptide F-like receptor 0.0221 0.0754 0.0753
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.001 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0077 0.0163
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0014 0.0014
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0221 0.0754 0.1524
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0039 0.0107 0.0216
Schistosoma mansoni tubulin subunit beta 0.0011 0.0007 0.0006
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0071 0.015
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0156 0.0524 0.0524
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0111 0.0111
Toxoplasma gondii subtilisin SUB12 0.0262 0.09 0.191
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0143 0.0728
Schistosoma mansoni notch 0.0282 0.0971 0.097
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0017 0.0017
Echinococcus multilocularis G-protein coupled receptor, putative 0.0221 0.0754 0.1524
Brugia malayi Dopamine receptor protein 1 0.0221 0.0754 0.0757
Echinococcus multilocularis lamin 0.0023 0.005 0.0099
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0221 0.0754 0.1524
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0918 0.3237 0.3253
Schistosoma mansoni biogenic amine receptor 0.0221 0.0754 0.0753
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0067 0.0207 0.0438
Trypanosoma cruzi hypothetical protein, conserved 0.1331 0.4709 1
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0013 0.0013 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0011 0.0008 0.0007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0046
Echinococcus granulosus Chromo domain 0.0011 0.0008 0.0015
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0239 0.0238
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0484 0.1691 0.3422
Schistosoma mansoni egf-like domain protein 0.0268 0.0922 0.0922
Echinococcus multilocularis transmembrane protease serine 3 0.0484 0.1691 0.3422
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0104 0.1152
Onchocerca volvulus 0.0038 0.0102 0.0103
Brugia malayi cell division control protein 2 homolog 0.0027 0.0065 0.0065
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0008 0.0023
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.008 0.0246
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0054 0.0158 0.0335
Loa Loa (eye worm) hypothetical protein 0.0275 0.0947 0.0952
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0054 0.0158 0.0335
Echinococcus multilocularis Tubulin beta 2C chain 0.0011 0.0007 0.0013
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0023 0.0049 0.0104
Schistosoma mansoni chromobox protein 0.007 0.0217 0.0216
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0008 0.0015
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.002 0.004 0.011
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 1
Echinococcus granulosus tubulin beta 1 chain 0.0011 0.0007 0.0014
Schistosoma mansoni cellular tumor antigen P53 0.0043 0.0119 0.0118
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0008 0.0015
Schistosoma mansoni neuropeptide receptor 0.0221 0.0754 0.0753
Onchocerca volvulus 0.0041 0.0111 0.0112
Loa Loa (eye worm) melatonin receptor type 1A 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0001 0.0001
Loa Loa (eye worm) G-protein coupled receptor 0.0221 0.0754 0.0757
Loa Loa (eye worm) trypsin family protein 0.0484 0.1691 0.17
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0918 0.3237 0.3253
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0023 0.0046
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0054 0.0158 0.0335
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0013 0.0013 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0617 0.2165 0.4597
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0014 0.0029
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0055 0.0164 0.0348
Echinococcus multilocularis neuropeptide receptor A26 0.0617 0.2165 0.438
Trypanosoma cruzi GMP reductase 0.0048 0.0137 0.029
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Schistosoma mansoni diflavin oxidoreductase 0.0027 0.0062 0.0061
Schistosoma mansoni carbonic anhydrase 0.0547 0.1916 0.1916
Trypanosoma brucei protein kinase, putative 0.003 0.0075 0.0231
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0484 0.1691 0.1691
Echinococcus granulosus geminin 0.0171 0.0574 0.1219
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0065 0.0064
Brugia malayi MH2 domain containing protein 0.02 0.0681 0.0683
Leishmania major cytochrome P450 reductase, putative 0.0048 0.0137 0.0289
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0008 0.0014
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0134 0.0443 0.094
Giardia lamblia Nitric oxide synthase, inducible 0.0048 0.0137 0.1346
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0103 0.0335 0.0334
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Onchocerca volvulus 0.0043 0.0118 0.0119
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0099 0.032 0.0647
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0054 0.0108
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0041 0.0111 0.0235
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.008 0.0869
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0039 0.0107 0.0226
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0156 0.0524 0.6046
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0156 0.0524 0.6046
Onchocerca volvulus 0.0011 0.0008 0.0008
Onchocerca volvulus 0.0484 0.1691 0.17
Loa Loa (eye worm) hypothetical protein 0.0484 0.1691 0.17
Brugia malayi Trypsin family protein 0.0484 0.1691 0.17
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0221 0.0754 0.1524
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0156 0.0524 0.6046
Loa Loa (eye worm) PAN domain-containing protein 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis RUN 0.0024 0.0054 0.0108
Giardia lamblia Hypothetical protein 0.0048 0.0137 0.1346
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0023 0.0071
Onchocerca volvulus 0.0262 0.09 0.0904
Onchocerca volvulus 0.0262 0.09 0.0904
Schistosoma mansoni loxhd1 0.0024 0.0054 0.0053
Echinococcus multilocularis glycoprotein Antigen 5 0.0484 0.1691 0.3422
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0068 0.0211 0.0447
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0078 0.0156
Echinococcus multilocularis dro:myosuppressin receptor 0.0221 0.0754 0.1524
Loa Loa (eye worm) hypothetical protein 0.0054 0.0158 0.0159
Plasmodium falciparum cysteine repeat modular protein 1 0.1331 0.4709 1
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0282 0.0971 0.0975
Echinococcus granulosus neuropeptide receptor 0.0221 0.0754 0.16
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0107 0.0107
Echinococcus multilocularis protein jagged 2 0.0282 0.0971 0.1963
Toxoplasma gondii PAN domain-containing protein 0.1329 0.4703 0.9987
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0077
Echinococcus granulosus dnaJ subfamily B 0.0686 0.2412 0.5122
Trypanosoma brucei beta tubulin 0.0011 0.0007 0.002
Brugia malayi Trypsin family protein 0.0484 0.1691 0.17
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0017 0.0034
Schistosoma mansoni hypothetical protein 0.1331 0.4709 0.4708
Echinococcus multilocularis fibrillin 1 0.0268 0.0922 0.1865
Schistosoma mansoni transcription factor LCR-F1 0.0062 0.0188 0.0187
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.004 0.0083
Onchocerca volvulus 0.0039 0.0104 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0038 0.0102 0.0102
Echinococcus granulosus cyclin dependent kinase 0.0027 0.0065 0.0136
Schistosoma mansoni smad1 5 8 and 0.0014 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0032 0.008 0.0169
Schistosoma mansoni amine GPCR 0.0751 0.2644 0.2643
Schistosoma mansoni biogenic amine receptor 0.0221 0.0754 0.0753
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0008 0.0015
Leishmania major inosine-5-monophosphate dehydrogenase 0.0048 0.0137 0.029
Echinococcus granulosus Mastin 0.0484 0.1691 0.3591
Plasmodium vivax tubulin beta chain, putative 0.0011 0.0007 0.0014
Onchocerca volvulus Arrow homolog 0.0275 0.0947 0.0952
Brugia malayi SET domain containing protein 0.0014 0.0015 0.0015
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.004 0.0401
Onchocerca volvulus Putative cubilin 0.0289 0.0996 0.1001
Brugia malayi Doublecortin family protein 0.0024 0.0054 0.0054
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0275 0.0947 0.0952
Onchocerca volvulus 0.0221 0.0754 0.0758
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.008 0.0869
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.003 0.0075 0.0159
Brugia malayi Calcium binding EGF domain containing protein 0.0268 0.0922 0.0926
Echinococcus multilocularis cpg binding protein 0.0051 0.0148 0.0299
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Brugia malayi Heterochromatin protein 1 0.007 0.0217 0.0217
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0491 0.1717 0.1716
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0041 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0103 0.0103
Brugia malayi beta-lactamase 0.0031 0.0077 0.0077
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0048 0.0137 0.2674
Echinococcus granulosus mixed lineage leukemia protein mll 0.0013 0.0013 0.0027
Brugia malayi steroid hormone receptor 0.0013 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0008 0.0009
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.002 0.004 0.011
Onchocerca volvulus 0.0262 0.09 0.0904
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0039 0.0107 0.0107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0039 0.0107 0.0107
Leishmania major hypothetical protein, conserved 0.0013 0.0013 0.0026
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.004 0.0083
Echinococcus multilocularis peptidase Clp (S14 family) 0.0044 0.0124 0.025
Mycobacterium ulcerans esterase/lipase LipP 0.0031 0.0077 0.0336
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0547 0.1916 0.1926
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0064 0.0196 0.0395
Brugia malayi Delta serrate ligand family protein 0.0282 0.0971 0.0975
Toxoplasma gondii hypothetical protein 0.0041 0.0111 0.0235
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0054 0.0113
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0011 0.0023
Brugia malayi nuclear hormone receptor 0.0013 0.0014 0.0014
Brugia malayi G protein-coupled receptor F59B2.13 0.0221 0.0754 0.0757
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0044 0.0124 0.2314
Brugia malayi Pre-SET motif family protein 0.021 0.0717 0.072
Plasmodium falciparum carbonic anhydrase 0.0547 0.1916 0.4069
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0077 0.0077
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0221 0.0754 0.16
Brugia malayi beta-lactamase family protein 0.0031 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis ubiquitin specific protease 41 0.0032 0.008 0.0161
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0221 0.0754 0.0757
Trichomonas vaginalis CMGC family protein kinase 0.003 0.0075 0.0812
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0077 0.0834
Brugia malayi latrophilin 2 splice variant baaae 0.0028 0.0066 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0013 0.0014 0.0014
Echinococcus multilocularis G protein coupled receptor 139 0.0221 0.0754 0.1524
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0123 0.0405 0.2297
Brugia malayi Melatonin receptor type 1A 0.0221 0.0754 0.0757
Echinococcus granulosus glycoprotein Antigen 5 0.0484 0.1691 0.3591
Loa Loa (eye worm) G-protein coupled receptor 0.0221 0.0754 0.0757
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.007 0.0147
Toxoplasma gondii IMP dehydrogenas 0.0048 0.0137 0.029
Toxoplasma gondii kringle domain-containing protein 0.1331 0.4709 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0221 0.0754 0.1524
Loa Loa (eye worm) hypothetical protein 0.0041 0.0112 0.0112
Toxoplasma gondii PAN domain-containing protein 0.0262 0.09 0.191
Echinococcus multilocularis cyclin dependent kinase 5 0.0027 0.0065 0.013
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0014 0.0029
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Schistosoma mansoni amine GPCR 0.0221 0.0754 0.0753
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.008 0.0169
Echinococcus multilocularis neuropeptide receptor 0.0221 0.0754 0.1524
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0047 0.0477
Schistosoma mansoni hypothetical protein 0.0221 0.0754 0.0753
Onchocerca volvulus 0.0282 0.0971 0.0975
Brugia malayi Serotonin receptor 0.0221 0.0754 0.0757
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0055 0.0161 0.0341
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0014 0.0027
Echinococcus granulosus survival motor neuron protein 1 0.0204 0.0692 0.1469
Brugia malayi hypothetical protein 0.0062 0.0188 0.0188
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0033 0.0085 0.0085
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0116 0.038 0.4361
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0077 0.1033
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0143 0.1905
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0013 0.0014 0.0014
Echinococcus granulosus alpha 1A adrenergic receptor 0.0221 0.0754 0.16
Loa Loa (eye worm) tubulin beta-1 chain 0.0011 0.0007 0.0006
Mycobacterium tuberculosis Conserved protein 0.0031 0.0077 0.0903
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0048 0.0047
Onchocerca volvulus Neurogenic locus notch homolog 0.0282 0.0971 0.0975
Brugia malayi neuropeptide F receptor 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0123 0.0405 0.1251
Onchocerca volvulus Slit protein homolog 0.0282 0.0971 0.0975
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0048 0.0137 0.0422
Trypanosoma cruzi cdc2-related kinase 1 0.0027 0.0065 0.0136
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.004 0.0388
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.026 0.0893 0.1896
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0014 0.0014
Schistosoma mansoni opsin-like receptor 0.0221 0.0754 0.0753
Onchocerca volvulus 0.0221 0.0754 0.0758
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0023 0.0049 0.0113
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.004 0.011
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus granulosus protein jagged 2 0.0282 0.0971 0.206
Echinococcus granulosus neuropeptides capa receptor 0.0221 0.0754 0.16
Loa Loa (eye worm) pax transcription factor protein 2 0.0242 0.083 0.0833
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0067 0.0207 0.0438
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0071 0.0071
Toxoplasma gondii PAN domain-containing protein 0.0262 0.09 0.191
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0547 0.1916 0.1926
Echinococcus granulosus tm gpcr rhodopsin 0.0221 0.0754 0.16
Entamoeba histolytica hypothetical protein 0.0062 0.0188 0.2109
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Brugia malayi larval opioid receptor 0.0221 0.0754 0.0757
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0547 0.1916 0.1926
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0097 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Loa Loa (eye worm) carbonic anhydrase 3 0.0918 0.3237 0.3253
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0221 0.0754 0.0757
Echinococcus granulosus methionine synthase reductase 0.0033 0.0085 0.018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0014 0.0014
Schistosoma mansoni neuropeptide receptor 0.0221 0.0754 0.0753
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Loa Loa (eye worm) hypothetical protein 0.2802 0.995 1
Onchocerca volvulus 0.0042 0.0115 0.0115
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0156 0.0524 0.1112
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0014 0.0015 0.003
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0077 0.0237
Schistosoma mansoni carbonic anhydrase-related 0.0547 0.1916 0.1916
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.0065 0.0688
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0039
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Onchocerca volvulus Alhambra homolog 0.0029 0.0071 0.0072
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Trypanosoma cruzi cdc2-related kinase 3 0.0027 0.0065 0.0136
Echinococcus multilocularis tubulin subunit beta 0.0011 0.0007 0.0013
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0547 0.1916 0.1926
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0045 0.0127 0.0634
Echinococcus granulosus tm gpcr rhodopsin 0.0221 0.0754 0.16
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0049 0.0143 0.0142
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0484 0.1691 0.1691
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0049 0.0143 0.0288
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0103 0.0103
Onchocerca volvulus 0.0221 0.0754 0.0758
Schistosoma mansoni slit 0.0282 0.0971 0.097
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Onchocerca volvulus 0.0023 0.005 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0062 0.0188 0.0397
Echinococcus granulosus Tolloid protein 1 0.0275 0.0947 0.2011
Brugia malayi intermediate filament protein 0.0023 0.005 0.0049
Mycobacterium tuberculosis Probable lipase LipE 0.0031 0.0077 0.0903
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Onchocerca volvulus 0.0221 0.0754 0.0758
Trypanosoma brucei beta tubulin 0.0011 0.0007 0.002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0484 0.1691 0.1691
Onchocerca volvulus 0.1331 0.4709 0.4732
Onchocerca volvulus 0.0011 0.0008 0.0008
Trichomonas vaginalis hypothetical protein 0.0011 0.0008 0.0023
Brugia malayi Calcium binding EGF domain containing protein 0.0282 0.0971 0.0975
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0071 0.015
Echinococcus granulosus Tubulin beta 2C chain 0.0011 0.0007 0.0014
Onchocerca volvulus Neuropeptide F receptor homolog 0.0221 0.0754 0.0758
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Brugia malayi Calcium binding EGF domain containing protein 0.0289 0.0996 0.1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0123 0.0405 0.5909
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis neurogenic locus protein delta 0.0282 0.0971 0.1963
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0156 0.0524 0.0526
Schistosoma mansoni carbonic anhydrase-related 0.0547 0.1916 0.1916
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.004 0.0388
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0012
Echinococcus multilocularis chromobox protein 2 0.0011 0.0008 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0014 0.0027
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0013 0.0013 0.0012
Echinococcus multilocularis dual specificity 0.0055 0.0164 0.0331
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0057 0.0169 0.0521
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0547 0.1916 0.1926
Plasmodium vivax glycogen synthase kinase 3, putative 0.003 0.0075 0.0159
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis microtubule associated protein 2 0.1188 0.42 0.85
Echinococcus granulosus poly ADP ribose polymerase 1 0.0099 0.032 0.068
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0156 0.0524 0.0526
Schistosoma mansoni notch 0.0282 0.0971 0.097
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0008 0.0023
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.004 0.0388
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0221 0.0754 0.0753
Echinococcus multilocularis neuropeptide Y receptor 0.0221 0.0754 0.1524
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0093 0.0188
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0918 0.3237 0.3236
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0054 0.0158 0.0335
Loa Loa (eye worm) hypothetical protein 0.0282 0.0972 0.0976
Echinococcus multilocularis smad 0.0014 0.0015 0.003
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0262 0.09 0.191
Echinococcus granulosus RUN 0.0024 0.0054 0.0113
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0221 0.0754 0.0753
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0057 0.0169 0.017
Loa Loa (eye worm) hypothetical protein 0.027 0.0931 0.0935
Echinococcus granulosus g-protein coupled receptor 0.0221 0.0754 0.16
Toxoplasma gondii hypothetical protein 0.0042 0.0116 0.0246
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0014 0.0014
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0054 0.0113
Entamoeba histolytica cell division protein kinase 2, putative 0.0027 0.0065 0.0675
Echinococcus multilocularis protein jagged 1 0.0282 0.0971 0.1963
Toxoplasma gondii microneme protein MIC17C 0.0262 0.09 0.191
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Toxoplasma gondii PAN/Apple domain-containing protein 0.0262 0.09 0.191
Trichomonas vaginalis esterase, putative 0.0031 0.0077 0.0834
Echinococcus granulosus glycogen synthase kinase 3 beta 0.003 0.0075 0.0159
Schistosoma mansoni tar DNA-binding protein 0.0161 0.054 0.0539
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis protein kinase shaggy 0.003 0.0075 0.0151
Echinococcus multilocularis protein tyrosine kinase 0.01 0.0323 0.0652
Onchocerca volvulus Putative GMP reductase 0.002 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0057 0.0169 0.0358
Schistosoma mansoni chromobox protein 0.0011 0.0008 0.0007
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0048 0.0137 0.029
Onchocerca volvulus 0.0221 0.0754 0.0758
Onchocerca volvulus 0.0262 0.09 0.0904
Mycobacterium tuberculosis Conserved protein 0.0031 0.0077 0.0903
Schistosoma mansoni hypothetical protein 0.0484 0.1691 0.1691
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0221 0.0754 0.1524
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0918 0.3237 0.3236
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0282 0.0971 0.0975
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0071 0.0143
Echinococcus granulosus TGF beta signal transducer SmadC 0.0014 0.0015 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0039 0.0107 0.0107
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0023 0.0048 0.0159
Mycobacterium ulcerans hypothetical protein 0.002 0.004 0.011
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0008 0.0023
Brugia malayi GnHR receptor homolog 0.0221 0.0754 0.0757
Entamoeba histolytica hypothetical protein 0.0055 0.0164 0.1837
Schistosoma mansoni lamin 0.0023 0.005 0.0049
Trypanosoma brucei cdc2-related kinase 3 0.0027 0.0065 0.0198
Onchocerca volvulus 0.0282 0.0971 0.0975
Loa Loa (eye worm) MH1 domain-containing protein 0.0014 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0047 0.0477
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 0.1111
Echinococcus granulosus microtubule associated protein 2 0.1188 0.42 0.892
Trichomonas vaginalis tubulin epsilon chain, putative 0.0011 0.0007 0.0014
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0221 0.0754 0.16
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0054 0.0158 0.0488
Echinococcus multilocularis cyclin dependent kinase 0.0027 0.0065 0.013
Echinococcus granulosus beta tubulin 0.0011 0.0007 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0014 0.0014
Echinococcus multilocularis cyclin dependent kinase 1 0.0027 0.0065 0.013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0078 0.0077
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0041 0.0111 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0107 0.1179
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0161 0.054 0.0542
Echinococcus multilocularis cyclin dependent kinase 1 0.0027 0.0065 0.013
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0156 0.0524 0.0526
Onchocerca volvulus 0.0484 0.1691 0.17
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0075 0.0799
Echinococcus granulosus neuropeptide Y receptor 0.0221 0.0754 0.16
Onchocerca volvulus 0.0221 0.0754 0.0758
Echinococcus granulosus Chromobox protein 3 0.0011 0.0008 0.0015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.001 0.0021
Brugia malayi AMP-binding enzyme family protein 0.002 0.004 0.0039
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0027 0.0065 0.0136
Echinococcus multilocularis orexin receptor type 2 0.0221 0.0754 0.1524
Brugia malayi hypothetical protein 0.0024 0.0054 0.0054
Onchocerca volvulus 0.0262 0.09 0.0904
Echinococcus multilocularis fibropellin Ia 0.0282 0.0971 0.1963
Brugia malayi Bromodomain containing protein 0.0029 0.0071 0.0071
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0484 0.1691 0.3591
Brugia malayi sulfakinin receptor protein 0.0221 0.0754 0.0757
Onchocerca volvulus 0.0024 0.0054 0.0054
Plasmodium vivax SET domain protein, putative 0.0031 0.0078 0.0164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0039 0.0107 0.0107
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Trypanosoma brucei DNA repair protein, putative 0.0013 0.0013 0.0038
Echinococcus granulosus g protein coupled receptor 0.0221 0.0754 0.16
Onchocerca volvulus 0.0724 0.2547 0.256
Mycobacterium tuberculosis Probable esterase LipL 0.0031 0.0077 0.0903
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0041 0.0111 0.0224
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0047 0.0135 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Echinococcus granulosus raf serine:threonine protein kinase 0.0132 0.0439 0.0931
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0221 0.0754 0.0757
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0014 0.0014
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0023 0.0046
Echinococcus multilocularis beta tubulin 0.0011 0.0007 0.0013
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0054 0.0158 0.032
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0221 0.0754 0.0758
Loa Loa (eye worm) hypothetical protein 0.0031 0.0078 0.0077
Echinococcus granulosus 7TM GPCR rhodopsin 0.0221 0.0754 0.16
Schistosoma mansoni tyrosine kinase 0.01 0.0323 0.0322
Brugia malayi WGR domain containing protein 0.0099 0.032 0.0322
Schistosoma mansoni carbonic anhydrase-related 0.0547 0.1916 0.1916
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.008 0.0869
Entamoeba histolytica hypothetical protein 0.0062 0.0188 0.2109
Brugia malayi AKH receptor 0.0221 0.0754 0.0757
Echinococcus granulosus 7tm_1 domain containing protein 0.0221 0.0754 0.16
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0054 0.0158 0.0335
Schistosoma mansoni smad 0.0014 0.0015 0.0015
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0134 0.0443 0.0445
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0023 0.0049 0.0104
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0078 0.0077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0014 0.0029
Echinococcus multilocularis serotonin receptor 0.0319 0.1103 0.2231
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0023 0.0049
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 0.0438
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.004 0.0388
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0252 0.0863 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.008 0.0169
Trichomonas vaginalis chromobox protein, putative 0.007 0.0217 0.2459
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0047 0.0477
Echinococcus multilocularis enteropeptidase 0.0484 0.1691 0.3422
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0031 0.0077 0.0903
Schistosoma mansoni opsin-like receptor 0.0221 0.0754 0.0753
Echinococcus granulosus poly (ADP ribose) polymerase 0.0015 0.0022 0.0045
Entamoeba histolytica protein kinase, putative 0.0055 0.0164 0.1837
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0041 0.0111 0.0111
Echinococcus multilocularis neural cadherin 0.0282 0.0971 0.1963
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0014 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.0617 0.2165 0.438
Plasmodium falciparum acyl-CoA synthetase 0.0015 0.0021 0.0044
Loa Loa (eye worm) hypothetical protein 0.0484 0.1691 0.17
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0039 0.0107 0.0226
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Onchocerca volvulus 0.0039 0.0104 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0014 0.0014
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0021 0.004 0.0084
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0057 0.0169 0.1896
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0014 0.0014
Loa Loa (eye worm) PAN domain-containing protein 0.0262 0.09 0.0904
Leishmania major guanosine monophosphate reductase 0.0048 0.0137 0.029
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0066 0.0702
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0484 0.1691 0.3591
Onchocerca volvulus 0.0043 0.0119 0.0119
Brugia malayi Latrophilin receptor protein 2 0.0013 0.0013 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0221 0.0754 0.0753
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 1
Loa Loa (eye worm) flavodoxin family protein 0.0021 0.004 0.004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0067 0.0207 0.4577
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0023 0.0048 0.0225
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0071 0.0071
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0008 0.0015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0032 0.008 0.0161
Loa Loa (eye worm) neuropeptide F receptor 0.0221 0.0754 0.0757
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0048 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0076 0.0236 0.0237
Trypanosoma brucei cdc2-related kinase 1 0.0027 0.0065 0.0198
Toxoplasma gondii calcium binding egf domain-containing protein 0.0268 0.0922 0.1957
Brugia malayi G-protein coupled receptor 0.0221 0.0754 0.0757
Echinococcus multilocularis g protein coupled receptor 0.0221 0.0754 0.1524
Plasmodium vivax cysteine repeat modular protein 1, putative 0.1331 0.4709 1
Echinococcus granulosus notch 0.0282 0.0971 0.206
Entamoeba histolytica type A flavoprotein, putative 0.0021 0.004 0.0388
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0055 0.0161 0.0161
Brugia malayi ORL1-like opioid receptor 0.0221 0.0754 0.0757
Echinococcus granulosus Tubulin beta 2C chain 0.0011 0.0007 0.0014
Onchocerca volvulus 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Plasmodium vivax protein kinase Crk2 0.0027 0.0065 0.0136
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Echinococcus granulosus lamin 0.0023 0.005 0.0104
Schistosoma mansoni intermediate filament proteins 0.0023 0.005 0.0049
Giardia lamblia Rab geranylgeranyltransferase 0.0041 0.0111 0.1083
Giardia lamblia PHD finger protein 15 0.0029 0.0071 0.0668
Echinococcus granulosus neuropeptide FF receptor 2 0.0221 0.0754 0.16
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0008 0.0015
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 0.2023
Loa Loa (eye worm) CMGC/GSK protein kinase 0.003 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus granulosus fibropellin Ia 0.0282 0.0971 0.206
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0032 0.008 0.0856
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0047 0.0477
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Onchocerca volvulus 0.0262 0.09 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0107 0.1179
Echinococcus granulosus neurogenic locus notch protein 4 0.0282 0.0971 0.206
Brugia malayi putative neuropeptide receptor NPR1 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0319 0.1103 0.1108
Loa Loa (eye worm) TK/ROR protein kinase 0.1333 0.4715 0.4739
Toxoplasma gondii hypothetical protein 0.0023 0.0049 0.0104
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0221 0.0754 0.0757
Echinococcus granulosus neuropeptides capa receptor 0.0221 0.0754 0.16
Loa Loa (eye worm) MH2 domain-containing protein 0.02 0.0681 0.0683
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0041 0.0111 0.0235
Loa Loa (eye worm) hypothetical protein 0.1331 0.4709 0.4732
Echinococcus granulosus protein tyrosine kinase 0.01 0.0323 0.0684
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0013 0.0014 0.0014
Schistosoma mansoni growth hormone secretagogue receptor 0.0221 0.0754 0.0753
Schistosoma mansoni hypothetical protein 0.0221 0.0754 0.0753
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0041 0.0111 0.0235
Onchocerca volvulus 0.0221 0.0754 0.0758
Echinococcus granulosus beta tubulin 0.0011 0.0007 0.0014
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0156 0.0524 0.106
Onchocerca volvulus 0.0262 0.09 0.0904
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0075 0.0799
Echinococcus granulosus neuropeptide Y receptor 0.0221 0.0754 0.16
Mycobacterium ulcerans hypothetical protein 0.0484 0.1691 1
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis fat cadherin tumor suppressor 0.0282 0.0971 0.1963
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0011 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Schistosoma mansoni amine GPCR 0.0221 0.0754 0.0753
Loa Loa (eye worm) IMP dehydrogenase 1 0.0048 0.0137 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.003 0.0075 0.0812
Onchocerca volvulus 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0484 0.1691 0.17
Echinococcus multilocularis CDC7 cell division cycle 7 0.0039 0.0104 0.021
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0014 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0104 0.1152
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0054 0.0113
Toxoplasma gondii beta tubulin 0.0011 0.0007 0.0014
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0008 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Entamoeba histolytica protein kinase domain containing protein 0.0055 0.0164 0.1837
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0547 0.1916 0.1926
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0049
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0027 0.0065 0.0136
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Onchocerca volvulus 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Loa Loa (eye worm) raf kinase 0.0131 0.0432 0.0434
Schistosoma mansoni septate junction protein 0.0282 0.0971 0.097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.004 0.0326
Schistosoma mansoni adenoreceptor 0.0221 0.0754 0.0753
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0044 0.0124 0.1618
Loa Loa (eye worm) hypothetical protein 0.0547 0.1916 0.1926
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.004 0.011
Schistosoma mansoni hypothetical protein 0.0028 0.0066 0.0065
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.002 0.0038 0.0037
Echinococcus granulosus smad 0.0014 0.0015 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0059 0.0059
Echinococcus granulosus neurogenic locus notch protein 0.0282 0.0971 0.206
Brugia malayi RE15519p 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0027 0.0065 0.0065
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0015 0.0021 0.0045
Trichomonas vaginalis tubulin gamma chain, putative 0.0011 0.0007 0.0014
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Brugia malayi PHD-finger family protein 0.0012 0.0011 0.001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0057 0.0169 0.0358
Echinococcus granulosus fmrfamide receptor 0.0221 0.0754 0.16
Trichomonas vaginalis tubulin beta chain, putative 0.0011 0.0007 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0071 0.015
Schistosoma mansoni notch 0.0282 0.0971 0.097
Echinococcus multilocularis laminin 0.0268 0.0922 0.1865
Schistosoma mansoni tubulin subunit beta 0.0011 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0282 0.0971 0.097
Schistosoma mansoni biogenic amine (5HT) receptor 0.0221 0.0754 0.0753
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) GMP reductase 0.002 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0047 0.0477
Giardia lamblia Kinase, CDC7 0.0039 0.0104 0.1013
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Toxoplasma gondii microneme protein, putative 0.0262 0.09 0.191
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Schistosoma mansoni rab6-interacting 0.0024 0.0054 0.0053
Brugia malayi Muscle positioning protein 4 0.032 0.1106 0.1111
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0029 0.0266
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0014 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.1188 0.42 0.42
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0054
Echinococcus granulosus transcription factor Dp 1 0.0033 0.0084 0.0177
Brugia malayi jmjC domain containing protein 0.0038 0.0103 0.0103
Loa Loa (eye worm) TYRA-2 protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0044 0.0124 0.1618
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0077 0.0834
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0025 0.0056 0.0582
Loa Loa (eye worm) hypothetical protein 0.0289 0.0996 0.1
Echinococcus granulosus carbonic anhydrase 0.0547 0.1916 0.4069
Onchocerca volvulus 0.0262 0.09 0.0904
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0032 0.008 0.008
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0031 0.0077 0.0077
Echinococcus granulosus protein kinase shaggy 0.003 0.0075 0.0159
Trypanosoma brucei beta tubulin 0.0011 0.0007 0.002
Onchocerca volvulus 0.2802 0.995 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0037 0.0097 0.0298
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0014 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0221 0.0754 0.1524
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0008 0.0009
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0031 0.0077 0.0077
Onchocerca volvulus 0.0484 0.1691 0.17
Schistosoma mansoni Smad4 0.0014 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0204 0.0692 0.0695
Schistosoma mansoni tar DNA-binding protein 0.0161 0.054 0.0539
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Toxoplasma gondii PAN domain-containing protein 0.1329 0.4703 0.9987
Brugia malayi hypothetical protein 0.0024 0.0054 0.0054
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0041 0.0111 0.0111
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0021 0.004 0.0084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0008 0.0023
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0021 0.004 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Toxoplasma gondii PAN domain-containing protein 0.0262 0.09 0.191
Brugia malayi SEA domain containing protein 0.0038 0.0102 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0041 0.0111 0.0342
Echinococcus multilocularis g protein coupled receptor 0.0221 0.0754 0.1524
Toxoplasma gondii beta-1 tubulin, putative 0.0011 0.0007 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0041 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0039
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0221 0.0754 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Echinococcus granulosus tissue type plasminogen activator 0.1331 0.4709 1
Echinococcus multilocularis chromobox protein 1 0.007 0.0217 0.0437
Brugia malayi CUB domain containing protein 0.0014 0.0017 0.0016
Toxoplasma gondii ABC1 family protein 0.0031 0.0077 0.0163
Schistosoma mansoni coup transcription factor 0.0013 0.0014 0.0014
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0008 0.0007
Echinococcus granulosus g protein coupled receptor 0.0221 0.0754 0.16
Echinococcus multilocularis notch 0.0282 0.0971 0.1963
Brugia malayi Trypsin family protein 0.2802 0.995 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0067 0.0207 0.0417
Onchocerca volvulus 0.0031 0.0077 0.0078
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0031 0.0077 0.0903
Loa Loa (eye worm) FAD binding domain-containing protein 0.0054 0.0158 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0252 0.0863 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Echinococcus granulosus Tubulin beta 2C chain 0.0011 0.0007 0.0014
Echinococcus granulosus laminin 0.0268 0.0922 0.1957
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0078 0.0077
Onchocerca volvulus 0.0024 0.0054 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0014 0.0014
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0049 0.0143 0.0302
Echinococcus granulosus chromobox protein 1 0.007 0.0217 0.0459
Echinococcus multilocularis Smad4 0.0014 0.0015 0.003
Onchocerca volvulus 0.0221 0.0754 0.0758
Brugia malayi beta-tubulin, identical 0.0011 0.0007 0.0006
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.003 0.0075 0.0075
Loa Loa (eye worm) notch protein 0.0282 0.0971 0.0975
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.026 0.0893 0.1896
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Brugia malayi Protein kinase domain containing protein 0.0027 0.0065 0.0065
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0143 0.0728
Echinococcus granulosus intermediate filament protein 0.0023 0.005 0.0104
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0013 0.0013 0.0038
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0014 0.0014
Chlamydia trachomatis sulfite reductase 0.0033 0.0085 0.3449
Toxoplasma gondii beta-tubulin, putative 0.0011 0.0007 0.0014
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0055 0.0164 0.0348
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0025 0.0056 0.0458
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0057 0.0169 0.0342
Entamoeba histolytica cell division protein kinase 2, putative 0.0027 0.0065 0.0675
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0045 0.0127 0.0269
Brugia malayi isocitrate dehydrogenase 0.0016 0.0023 0.0023
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0078 0.0156
Onchocerca volvulus DNA ligase 3 homolog 0.0013 0.0013 0.0013
Schistosoma mansoni alpha-1 adrenergic receptor 0.0221 0.0754 0.0753
Onchocerca volvulus 0.0221 0.0754 0.0758
Echinococcus multilocularis g-protein coupled receptor 0.0221 0.0754 0.1524
Leishmania major hypothetical protein, conserved 0.0021 0.004 0.0084
Schistosoma mansoni neuropeptide receptor 0.0221 0.0754 0.0753
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0064 0.0196 0.0414
Echinococcus granulosus neurogenic locus notch protein 0.0282 0.0971 0.206
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0041 0.0111 0.0224
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.0065 0.0688
Echinococcus multilocularis raf serine:threonine protein kinase 0.0132 0.0439 0.0887
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0057 0.0057
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0221 0.0754 0.1524
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0221 0.0754 0.0753
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0103 0.0103
Onchocerca volvulus 0.0221 0.0754 0.0758
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Loa Loa (eye worm) RNA binding protein 0.0161 0.054 0.0542
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0054 0.0158 0.0822
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0008 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0013 0.0014 0.0014
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0023 0.0081
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0112 0.0226
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0007 0.0013
Toxoplasma gondii flavodoxin domain-containing protein 0.0027 0.0062 0.013
Onchocerca volvulus 0.0031 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Onchocerca volvulus 0.0282 0.0971 0.0975
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Trypanosoma brucei beta tubulin 0.0011 0.0007 0.002
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0023 0.0049
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0054 0.0113
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0008 0.0007
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Entamoeba histolytica hypothetical protein 0.0015 0.0022 0.0173
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0021 0.004 0.0401
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0164 0.0164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0013 0.0014 0.0014
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0032 0.008 0.0169
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0054 0.0158 0.0488
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0221 0.0754 0.16
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0484 0.1691 0.17
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0013 0.0013 0.0025
Echinococcus multilocularis Tolloid protein 1 0.0275 0.0947 0.1916
Loa Loa (eye worm) FAD binding domain-containing protein 0.0033 0.0085 0.0085
Schistosoma mansoni neuropeptide f receptor 76f 0.0221 0.0754 0.0753
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0041 0.0111 0.0342
Brugia malayi Dopamine receptor protein 2 0.0221 0.0754 0.0757
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0014 0.0029
Echinococcus multilocularis mitogen activated protein kinase 11 0.0134 0.0443 0.0896
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0275 0.0947 0.0951
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0039
Trypanosoma brucei mitochondrial DNA polymerase beta 0.026 0.0893 0.2758
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Brugia malayi intracellular kinase 0.003 0.0075 0.0075
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0014 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0054 0.0108
Brugia malayi Smad1 0.0014 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0014 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0014 0.0015 0.0015
Loa Loa (eye worm) Smad1 0.0014 0.0015 0.0015
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Leishmania major beta tubulin 0.0011 0.0007 0.0014
Onchocerca volvulus 0.0282 0.0971 0.0975
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0014 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0252 0.0863 1
Echinococcus granulosus lamin dm0 0.0023 0.005 0.0104
Brugia malayi Trypsin-like protease protein 5 0.0484 0.1691 0.17
Echinococcus granulosus dual specificity 0.0055 0.0164 0.0348
Mycobacterium leprae Probable lipase LipE 0.0031 0.0077 0.1033
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0067 0.0207 1
Brugia malayi follicle stimulating hormone receptor 0.0221 0.0754 0.0757
Loa Loa (eye worm) tubulin beta chain 0.0011 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0221 0.0754 0.0753
Brugia malayi Protein kinase domain containing protein 0.0055 0.0164 0.0165
Echinococcus granulosus protein jagged 1 0.0282 0.0971 0.206
Loa Loa (eye worm) BEN-1 protein 0.0011 0.0007 0.0006
Brugia malayi MH2 domain containing protein 0.0014 0.0015 0.0015
Echinococcus multilocularis peregrin 0.0029 0.0071 0.0143
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0041 0.0111 0.1231
Schistosoma mansoni laminin gamma-3 chain 0.0282 0.0971 0.097
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0221 0.0754 0.1524
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0439 0.0438
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0055 0.0164 0.0506
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0275 0.0947 0.0951
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0221 0.0754 0.0753
Loa Loa (eye worm) latrophilin receptor protein 2 0.0013 0.0013 0.0012
Echinococcus multilocularis Tubulin beta 2C chain 0.0011 0.0007 0.0013
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0221 0.0754 0.1524
Echinococcus multilocularis methionine synthase reductase 0.0033 0.0085 0.0171
Loa Loa (eye worm) intermediate filament protein 0.0023 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0007
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0054 0.0108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0013 0.0013 0.0026
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0078 0.0164
Schistosoma mansoni notch 0.0282 0.0971 0.097
Brugia malayi MH2 domain containing protein 0.0014 0.0015 0.0015
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0221 0.0754 0.0753
Schistosoma mansoni cpg binding protein 0.0048 0.0138 0.0138
Leishmania major carbonic anhydrase-like protein 0.0918 0.3237 0.6874
Loa Loa (eye worm) hypothetical protein 0.0484 0.1691 0.17
Onchocerca volvulus Bile acid receptor homolog 0.0013 0.0014 0.0014
Trichomonas vaginalis tubulin epsilon chain, putative 0.0011 0.0007 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0077 0.0163
Loa Loa (eye worm) beta-lactamase 0.0031 0.0077 0.0077
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0097 0.0205
Schistosoma mansoni lamin 0.0023 0.005 0.0049
Echinococcus granulosus poly adp ribose polymerase 2 0.0055 0.0161 0.0341
Schistosoma mansoni peptidase Clp (S14 family) 0.0067 0.0207 0.0206
Brugia malayi Tachykinin-like peptides receptor 99D 0.0221 0.0754 0.0757
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0118 0.0118
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0077 0.0834
Echinococcus multilocularis neurogenic locus protein delta 0.0282 0.0971 0.1963
Brugia malayi Pax transcription factor protein 2 0.0242 0.083 0.0833
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Echinococcus multilocularis beta tubulin 0.0011 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0484 0.1691 0.17
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0057 0.0169 0.0358
Echinococcus granulosus dro:myosuppressin receptor 0.0221 0.0754 0.16
Schistosoma mansoni tubulin subunit beta 0.0011 0.0007 0.0006
Echinococcus multilocularis Tubulin beta 2C chain 0.0011 0.0007 0.0013
Brugia malayi Tubulin beta-1 chain 0.0011 0.0007 0.0006
Brugia malayi G protein-coupled receptor 0.0221 0.0754 0.0757
Schistosoma mansoni hypothetical protein 0.0221 0.0754 0.0753
Loa Loa (eye worm) CXXC zinc finger family protein 0.0048 0.0138 0.0139
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.002 0.0038 0.0037
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0071 0.0071
Onchocerca volvulus 0.0484 0.1691 0.17
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0078 0.0164
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Trypanosoma cruzi p450 reductase, putative 0.0054 0.0158 0.0335
Schistosoma mansoni hypothetical protein 0.0686 0.2412 0.2412
Echinococcus granulosus protein jagged 1 0.0282 0.0971 0.206
Onchocerca volvulus 0.0221 0.0754 0.0758
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0008 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0221 0.0754 0.16
Echinococcus multilocularis neuropeptide FF receptor 2 0.0221 0.0754 0.1524
Echinococcus granulosus carbonic anhydrase 0.0547 0.1916 0.4069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 0.0754 0.0753
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 0.0754 0.1524
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0027 0.0065 0.0136
Loa Loa (eye worm) hypothetical protein 0.0262 0.09 0.0904
Loa Loa (eye worm) hypothetical protein 0.0268 0.0922 0.0926
Loa Loa (eye worm) Carm1-pending protein 0.0064 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.0062 0.0188 0.0187
Loa Loa (eye worm) hypothetical protein 0.0319 0.1103 0.1108
Echinococcus multilocularis neurogenic locus notch protein 4 0.0282 0.0971 0.1963
Giardia lamblia Fructose-bisphosphate aldolase 0.0252 0.0863 0.8888
Brugia malayi GMP reductase 0.002 0.0038 0.0037
Echinococcus granulosus protein jagged 2 0.0282 0.0971 0.206
Brugia malayi beta-lactamase family protein 0.0031 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0547 0.1916 0.1916
Schistosoma mansoni cercarial elastase (S01 family) 0.0484 0.1691 0.1691
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0014 0.0027
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0117 0.1303
Schistosoma mansoni hypothetical protein 0.0042 0.0115 0.0114
Echinococcus granulosus poly (ADP ribose) polymerase 0.0031 0.0077 0.0162
Schistosoma mansoni tar DNA-binding protein 0.0161 0.054 0.0539
Loa Loa (eye worm) hypothetical protein 0.2802 0.995 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0221 0.0754 0.0753
Schistosoma mansoni hypothetical protein 0.0484 0.1691 0.1691
Brugia malayi TAR-binding protein 0.0161 0.054 0.0542
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0048 0.0137 0.029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0062 0.0188 0.0378
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0918 0.3237 0.3253
Loa Loa (eye worm) BEN-1 protein 0.0011 0.0007 0.0006
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.002 0.004 0.0326
Onchocerca volvulus 0.0221 0.0754 0.0758
Loa Loa (eye worm) hypothetical protein 0.0067 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0038 0.0102 0.0102
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0024 0.005
Brugia malayi PAN domain containing protein 0.0262 0.09 0.0904
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0077 0.0834
Echinococcus granulosus Tubulin beta 2C chain 0.0011 0.0007 0.0014
Trypanosoma brucei GMP reductase 0.0048 0.0137 0.0422
Loa Loa (eye worm) CDC7 protein kinase 0.0039 0.0104 0.0104
Plasmodium vivax flavodoxin domain containing protein 0.0048 0.0137 0.0289
Brugia malayi hypothetical protein 0.0484 0.1691 0.17
Echinococcus granulosus tubulin subunit beta 0.0011 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.004 0.0083
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Echinococcus granulosus Smad4 0.0014 0.0015 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0014 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.005 0.0146 0.0146
Toxoplasma gondii microneme protein MIC4 0.0262 0.09 0.191
Toxoplasma gondii microneme protein MIC17B 0.0262 0.09 0.191
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0066 0.0702
Trypanosoma cruzi beta tubulin, putative 0.0011 0.0007 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0104 0.1152
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0047 0.0477
Echinococcus granulosus mothers against decapentaplegic 5 0.0014 0.0015 0.0032
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0039 0.0106 0.0106
Echinococcus granulosus tm gpcr rhodopsin 0.0221 0.0754 0.16
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0918 0.3237 0.6874
Schistosoma mansoni chromobox protein 0.007 0.0217 0.0216
Echinococcus multilocularis neuropeptides capa receptor 0.0221 0.0754 0.1524
Plasmodium falciparum nitric oxide synthase, putative 0.0054 0.0158 0.0335
Onchocerca volvulus 0.0221 0.0754 0.0758
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0123 0.0405 0.086
Schistosoma mansoni neuropeptide F-like receptor 0.0221 0.0754 0.0753
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0123 0.0405 1
Loa Loa (eye worm) hypothetical protein 0.0282 0.0971 0.0975
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.005 0.0049
Mycobacterium tuberculosis Conserved protein 0.0031 0.0077 0.0903
Schistosoma mansoni tubulin subunit beta 0.0011 0.0007 0.0006
Echinococcus granulosus sex peptide receptor 0.0221 0.0754 0.16
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0221 0.0754 0.0753
Brugia malayi hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0008 0.0023
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0048 0.0137 0.0695
Brugia malayi Protein kinase domain containing protein 0.1333 0.4715 0.4739
Onchocerca volvulus 0.0262 0.09 0.0904
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0217 0.0217
Onchocerca volvulus 0.0013 0.0014 0.0014
Echinococcus multilocularis allatostatin A receptor 0.0221 0.0754 0.1524
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0008 0.0007
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0055 0.0161 0.0325
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0158 0.0159
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0221 0.0754 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0048 0.0137 0.1819
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0039 0.0107 0.0216
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 0.0754 0.16
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0057 0.0169 0.0358
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0023 0.0049
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.004 0.011
Mycobacterium tuberculosis Probable lipase LipD 0.0031 0.0077 0.0903
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0048 0.0137 0.0137
Schistosoma mansoni tubulin subunit beta 0.0011 0.0007 0.0006
Brugia malayi flavodoxin family protein 0.0021 0.004 0.004
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0134 0.0443 0.1368
Schistosoma mansoni neuropeptide receptor 0.0221 0.0754 0.0753
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.004 0.011
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0021 0.004 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.0023
Brugia malayi FAD binding domain containing protein 0.0033 0.0085 0.0085
Brugia malayi Kringle domain containing protein 0.1331 0.4709 0.4732
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0156 0.0524 0.1112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0026 0.0233
Brugia malayi EGF-like domain containing protein 0.0282 0.0971 0.0975
Echinococcus granulosus poly (ADP ribose) polymerase 0.0015 0.0022 0.0045
Echinococcus granulosus enteropeptidase 0.0484 0.1691 0.3591
Leishmania major DNA repair protein, putative 0.0013 0.0013 0.0026

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 7.3 uM Binding affinity against bovine brain nNOS (neuronal). ChEMBL. 10956202
Ki (binding) = 7.3 uM Binding affinity against bovine brain nNOS (neuronal). ChEMBL. 10956202
Ki (binding) = 631 uM Binding affinity against recombinant bovine Endothelial nitric oxide synthase. ChEMBL. 10956202
Ki (binding) = 631 uM Binding affinity against recombinant bovine Endothelial nitric oxide synthase. ChEMBL. 10956202
Ki (binding) = 1900 uM Binding affinity against recombinant murine Inducible nitric oxide synthase. ChEMBL. 10956202
Ki (binding) = 1900 uM Binding affinity against recombinant murine Inducible nitric oxide synthase. ChEMBL. 10956202
Ratio (binding) = 86 Ratio of binfing affinity of eNOS to nNOS ChEMBL. 10956202
Ratio (binding) = 260 Ratio of binfing affinity of iNOS to nNOS ChEMBL. 10956202

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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