Detailed information for compound 174141

Basic information

Technical information
  • TDR Targets ID: 174141
  • Name: 2-fluoro-5-nitroaniline
  • MW: 156.115 | Formula: C6H5FN2O2
  • H donors: 1 H acceptors: 2 LogP: 1.17 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc(c(c1)N)F
  • InChi: 1S/C6H5FN2O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,8H2
  • InChiKey: KJVBJICWGQIMOZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-fluoro-5-nitro-aniline
  • (2-fluoro-5-nitro-phenyl)amine
  • 369-36-8
  • ZINC00164646
  • SB 01381
  • 47125_FLUKA
  • EINECS 206-720-3
  • 155853_ALDRICH
  • Benzenamine, 2-fluoro-5-nitro-
  • NSC51768

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0414 0.3417 0.4721
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0136 0.1039 0.3462
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Treponema pallidum uridine phosphorylase (udp) 0.0075 0.0518 0.2261
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0414 0.3417 1
Echinococcus granulosus nuclear receptor nhr 48 0.0195 0.1547 0.2138
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0036 0.0128
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0414 0.3417 0.3417
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0073 0.0245
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.003 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0074 0.051 0.0496
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0074 0.051 0.0496
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0017 0.0023
Echinococcus granulosus lysine specific demethylase 5A 0.007 0.0478 0.0661
Loa Loa (eye worm) hypothetical protein 0.006 0.0394 0.0394
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0054 0.0074
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0065 0.0435 0.0602
Brugia malayi hypothetical protein 0.0195 0.1547 0.1535
Echinococcus multilocularis thymidylate synthase 0.0246 0.1983 0.274
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0014 0.0051
Brugia malayi nuclear hormone receptor 0.0414 0.3417 0.3408
Loa Loa (eye worm) hypothetical protein 0.0023 0.0073 0.0073
Loa Loa (eye worm) MH1 domain-containing protein 0.002 0.0048 0.0048
Brugia malayi dihydrofolate reductase family protein 0.01 0.0736 0.0723
Leishmania major protein kinase, putative 0.002 0.0047 0.0164
Echinococcus granulosus Nuclear hormone receptor HR96 0.0195 0.1547 0.2138
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0053 0.033 0.0316
Schistosoma mansoni glutaminase 0.1183 1 1
Echinococcus multilocularis smad 0.002 0.0048 0.0066
Loa Loa (eye worm) RecQ helicase 0.0024 0.0084 0.0084
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0414 0.3417 0.4721
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0414 0.3417 0.3408
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0359 0.2949 0.2949
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0055 0.035 0.1231
Schistosoma mansoni intermediate filament proteins 0.0062 0.0404 0.039
Brugia malayi hypothetical protein 0.0195 0.1547 0.1535
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0075 0.0518 0.1782
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0195 0.1547 0.2138
Loa Loa (eye worm) hypothetical protein 0.0063 0.0414 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0414 0.3417 0.3408
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0017 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0188 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.035 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0518 0.0518
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0065 0.0435 0.0602
Schistosoma mansoni smad1 5 8 and 0.002 0.0048 0.0034
Schistosoma mansoni hypothetical protein 0.0075 0.0518 0.0505
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0414 0.3417 0.3408
Brugia malayi hypothetical protein 0.0219 0.1748 0.1736
Onchocerca volvulus 0.0055 0.0345 0.1008
Schistosoma mansoni cpg binding protein 0.006 0.0394 0.0381
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.003 0.003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0058 0.0374 0.1215
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 0.0601
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0414 0.3417 0.4721
Schistosoma mansoni ap endonuclease 0.0036 0.0188 0.0174
Loa Loa (eye worm) hypothetical protein 0.0045 0.0266 0.0266
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0075 0.0522 0.0721
Brugia malayi hypothetical protein 0.0268 0.2167 0.2156
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0036 0.0077
Loa Loa (eye worm) hypothetical protein 0.0177 0.1396 0.1396
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0036 0.0188 0.0538
Brugia malayi conserved hypotetical protein 0.0195 0.1547 0.1535
Brugia malayi jmjC domain containing protein 0.0018 0.003 0.0016
Echinococcus granulosus lamin dm0 0.0062 0.0404 0.0558
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus granulosus intermediate filament protein 0.0062 0.0404 0.0558
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0414 0.3417 0.3408
Loa Loa (eye worm) steroid hormone receptor 0.0414 0.3417 0.3417
Brugia malayi Telomerase reverse transcriptase 0.0055 0.0346 0.0332
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0268 0.2168 1
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0055 0.035 0.0483
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0036 0.005
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0073 0.0037
Brugia malayi hypothetical protein 0.0219 0.1748 0.1736
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0226 0.0191
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0195 0.1547 0.1535
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0414 0.3417 0.4721
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0131 0.0997 0.3353
Brugia malayi Probable ClpP-like protease 0.0089 0.0635 0.0621
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.099 0.0977
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0414 0.3417 0.4721
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0414 0.3417 0.3408
Schistosoma mansoni nuclear receptor 0.0195 0.1547 0.1535
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0188 0.0188
Brugia malayi latrophilin 2 splice variant baaae 0.0026 0.0104 0.0089
Echinococcus granulosus phd:f box containing protein 0.0018 0.003 0.0041
Loa Loa (eye worm) hypoxia-induced factor 1 0.017 0.1335 0.1335
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0087 0.062 0.0606
Brugia malayi Nuclear hormone receptor-like 1 0.0219 0.1748 0.1736
Echinococcus granulosus alpha13fucosyltransferase 0.0075 0.0522 0.0721
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus granulosus geminin 0.0473 0.3925 0.5423
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0414 0.3417 0.3408
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.1547 0.2138
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0014 0.002
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0362 0.2972 1
Onchocerca volvulus 0.006 0.0394 0.1154
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0089 0.0635 0.2194
Brugia malayi Fli-1 protein 0.0223 0.1782 0.177
Schistosoma mansoni nuclear hormone receptor 0.0414 0.3417 0.3408
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0075 0.0518 0.1668
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0138 0.0439
Loa Loa (eye worm) nuclear receptor NHR-67 0.0195 0.1547 0.1547
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.003 0.0054
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0065 0.0435 0.1532
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.01 0.0736 0.0703
Chlamydia trachomatis endonuclease IV 0.0087 0.062 0.8417
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0414 0.3417 0.3408
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0151 0.117 0.1617
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0591 0.0816
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0414 0.3417 0.4721
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0131 0.0997 0.0964
Entamoeba histolytica hypothetical protein, conserved 0.0055 0.035 0.0817
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0478 0.0465
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0087 0.062 0.2046
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0036 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.033 0.0316
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0414 0.3417 0.3408
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0074 0.051 0.051
Brugia malayi hypothetical protein 0.0054 0.034 0.0326
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0414 0.3417 0.4721
Mycobacterium leprae probable uridine phosphorylase 0.0075 0.0518 0.1744
Brugia malayi hypothetical protein 0.0185 0.1458 0.1445
Echinococcus multilocularis PHD finger protein rhinoceros 0.0018 0.003 0.0041
Onchocerca volvulus 0.0053 0.033 0.0966
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0075 0.0518 0.0716
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0246 0.1983 0.6673
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0635 0.2194
Onchocerca volvulus 0.0062 0.0404 0.1182
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0414 0.3417 0.4721
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0019 0.0036 0.0492
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0414 0.3417 0.3408
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0361 0.2966 0.2966
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0591 0.0816
Schistosoma mansoni alpha(13)fucosyltransferase 0.0177 0.1396 0.1383
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0195 0.1547 0.2138
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0059 0.0082
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0036 0.0188 0.026
Schistosoma mansoni netrin receptor unc5 0.0016 0.0017 0.0002
Schistosoma mansoni alpha 13/4 fucosyltransferase Lewis 1 0.0102 0.0751 0.0738
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0055 0.035 0.1186
Echinococcus granulosus peregrin 0.0018 0.003 0.0041
Loa Loa (eye worm) uridine phosphorylase 0.0075 0.0518 0.0518
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0414 0.3417 0.4721
Mycobacterium tuberculosis Hypothetical protein 0.0117 0.0879 0.2924
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Schistosoma mansoni lamin 0.0062 0.0404 0.039
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.005 0.0303 0.0418
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0075 0.0518 0.1668
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0074 0.051 0.0704
Echinococcus multilocularis lysine specific demethylase 5A 0.0067 0.0449 0.062
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0505 0.0698
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Echinococcus multilocularis phd:f box containing protein 0.0018 0.003 0.0041
Brugia malayi Nuclear hormone receptor E75 0.0195 0.1547 0.1535
Schistosoma mansoni phd/f-box containing protein 0.0018 0.003 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0414 0.3417 0.3408
Brugia malayi ecdysone receptor 0.0195 0.1547 0.1535
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0122 0.0922 0.3068
Onchocerca volvulus 0.0195 0.1547 0.4528
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0414 0.3417 0.4721
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0075 0.0518 0.1782
Mycobacterium tuberculosis Probable oxidoreductase 0.0136 0.1039 0.3462
Chlamydia trachomatis dihydrofolate reductase 0.01 0.0736 1
Brugia malayi Nuclear hormone receptor-like 1 0.0414 0.3417 0.3408
Giardia lamblia Telomerase catalytic subunit 0.0021 0.0054 0.0082
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0362 0.2972 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.003 0.0054
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0036 0.0077
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0014 0.002
Schistosoma mansoni alpha(13)fucosyltransferase 0.0177 0.1396 0.1383
Brugia malayi jmjC domain containing protein 0.007 0.0478 0.0465
Echinococcus granulosus FTZ F1 alpha 0.0414 0.3417 0.4721
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Loa Loa (eye worm) hypothetical protein 0.0087 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Leishmania major eukaryotic translation initiation factor-like 0.0065 0.0435 0.1532
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0054 0.0074
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0017 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0219 0.1748 0.1736
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni ap endonuclease 0.0036 0.0188 0.0174
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0075 0.0518 0.0484
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0151 0.117 0.1158
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.003 0.0055
Entamoeba histolytica hypothetical protein 0.0075 0.0518 0.1668
Brugia malayi Thioredoxin reductase 0.0054 0.0335 0.0321
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.003 0.0041
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0036 0.0074
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0133 0.0469
Echinococcus granulosus methylthioadenosine phosphorylase 0.0075 0.0518 0.0716
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0414 0.3417 0.4721
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Echinococcus granulosus Transcription initiation factor TFIID subunit 0.0045 0.0266 0.0368
Echinococcus granulosus uridine phosphorylase 1 0.0075 0.0518 0.0716
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0414 0.3417 0.3417
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0138 0.0479
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0101 0.0087
Plasmodium vivax SET domain protein, putative 0.0053 0.033 0.1117
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0478 0.0478
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0017 0.0023
Schistosoma mansoni smad1 5 8 and 0.002 0.0048 0.0034
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0075 0.0518 0.1661
Trypanosoma brucei RNA helicase, putative 0.0075 0.0518 0.1782
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Plasmodium falciparum glutathione reductase 0.0019 0.0036 0.0077
Loa Loa (eye worm) hypothetical protein 0.0026 0.0104 0.0104
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.003 0.0041
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0036 0.0188 0.0587
Onchocerca volvulus 0.0246 0.1983 0.5804
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0075 0.0518 0.2261
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0055 0.035 0.1186
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0036 0.0128
Schistosoma mansoni methylthioadenosine phosphorylase 0.0075 0.0518 0.0505
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Loa Loa (eye worm) hypothetical protein 0.0252 0.2032 0.2032
Brugia malayi PAS domain containing protein 0.0055 0.0349 0.0335
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0132 0.0182
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0036 0.0077
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0055 0.035 0.1231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0074 0.051 0.0496
Echinococcus multilocularis geminin 0.0473 0.3925 0.5423
Schistosoma mansoni purine nucleoside phosphorylase 0.0362 0.2972 0.2962
Mycobacterium ulcerans glutaminase 0.1183 1 1
Echinococcus multilocularis Smad4 0.002 0.0048 0.0066
Loa Loa (eye worm) MH2 domain-containing protein 0.002 0.0048 0.0048
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0075 0.0518 0.1824
Echinococcus granulosus PHD finger protein rhinoceros 0.0018 0.003 0.0041
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0287 0.2331 0.3221
Plasmodium falciparum thioredoxin reductase 0.0054 0.0335 0.1135
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0362 0.2972 0.2972
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0072 0.0058
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0122 0.0922 0.3068
Loa Loa (eye worm) intermediate filament protein 0.0062 0.0404 0.0404
Mycobacterium tuberculosis Probable reductase 0.0122 0.0922 0.3068
Brugia malayi MH2 domain containing protein 0.0292 0.2379 0.2368
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Loa Loa (eye worm) hypothetical protein 0.0062 0.0404 0.0404
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0036 0.0077
Schistosoma mansoni cpg binding protein 0.0064 0.0424 0.041
Echinococcus granulosus dihydrofolate reductase 0.01 0.0736 0.1017
Brugia malayi jmjC domain containing protein 0.0018 0.003 0.0016
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Echinococcus multilocularis purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0414 0.3417 0.3417
Trichomonas vaginalis glutaminase, putative 0.1183 1 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0022 0.0031
Schistosoma mansoni hypothetical protein 0.0055 0.035 0.0336
Echinococcus multilocularis peregrin 0.0018 0.003 0.0041
Brugia malayi Protein kinase domain containing protein 0.0016 0.0017 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Echinococcus granulosus thyroid hormone receptor alpha 0.0195 0.1547 0.2138
Schistosoma mansoni nuclear hormone receptor 0.0195 0.1547 0.1535
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0059 0.0082
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0335 0.118
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0036 0.0077
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0414 0.3417 0.3417
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0073 0.0058
Echinococcus granulosus Nuclear hormone receptor HR96 0.0195 0.1547 0.2138
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0065 0.0435 0.1489
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0055 0.035 0.0483
Echinococcus multilocularis dihydrofolate reductase 0.01 0.0736 0.1017
Loa Loa (eye worm) nuclear hormone receptor 0.0195 0.1547 0.1547
Echinococcus multilocularis Ankyrin 0.0016 0.0018 0.0025
Onchocerca volvulus 0.0041 0.0226 0.0662
Schistosoma mansoni nuclear hormone receptor 0.0195 0.1547 0.1535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0414 0.3417 0.3417
Loa Loa (eye worm) DR-78 0.0195 0.1547 0.1547
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0054 0.0054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0039 0.0208 0.0194
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0074 0.051 0.0704
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0089 0.0635 0.0877
Schistosoma mansoni alpha(13)fucosyltransferase 0.0177 0.1396 0.1383
Brugia malayi alpha1,3-fucosyltransferase homologue 0.0177 0.1396 0.1383
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.01 0.0736 0.2477
Brugia malayi translation initiation factor 4E 0.0065 0.0435 0.0422
Schistosoma mansoni lamin 0.0062 0.0404 0.039
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0017 0.0023
Schistosoma mansoni microtubule-associated protein tau 0.0746 0.6259 0.6254
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.0763 0.1054
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0873 0.3036
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 0.8621
Brugia malayi glutaminase DH11.1 0.1183 1 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.0335 0.0463
Schistosoma mansoni zinc finger protein 0.0195 0.1547 0.1535
Echinococcus multilocularis purine nucleoside phosphorylase 0.0287 0.2331 0.3221
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.003 0.003
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0065 0.0435 0.1532
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0055 0.035 0.1231
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.0226 0.0312
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.1547 0.2138
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0014 0.0051
Toxoplasma gondii phosphorylase family protein 0.0075 0.0518 0.1782
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.033 0.0316
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0505 0.0698
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0065 0.0435 0.1249
Entamoeba histolytica DNA repair and recombination protein, putative 0.0055 0.035 0.0817
Echinococcus granulosus thymidylate synthase 0.0246 0.1983 0.274
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0022 0.0031
Echinococcus granulosus dnaJ subfamily B 0.086 0.7238 1
Echinococcus multilocularis purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0414 0.3417 0.3408
Echinococcus multilocularis cpg binding protein 0.0064 0.0424 0.0586
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0414 0.3417 0.3408
Loa Loa (eye worm) transcription factor SMAD2 0.0292 0.2379 0.2379
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0219 0.1748 0.2414
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0219 0.1748 0.1748
Schistosoma mansoni nuclear receptor nhr-48 0.0195 0.1547 0.1535
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0345 0.0331
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.033 0.0456
Leishmania major telomerase reverse transcriptase, putative 0.0021 0.0054 0.0189
Echinococcus multilocularis thyroid hormone receptor alpha 0.0414 0.3417 0.4721
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0518 0.1704
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0053 0.033 0.0456
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Leishmania major glycosyl transferase, putative 0.003 0.0133 0.0469
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0022 0.0031
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0036 0.0188 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0414 0.3417 0.3408
Echinococcus granulosus mothers against decapentaplegic 5 0.002 0.0048 0.0066
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0087 0.062 0.2141
Plasmodium vivax glutathione reductase, putative 0.0054 0.0335 0.1135
Echinococcus multilocularis musashi 0.0062 0.0404 0.0558
Brugia malayi nuclear receptor NHR-67 0.0195 0.1547 0.1535
Toxoplasma gondii thioredoxin reductase 0.0054 0.0335 0.1135
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.01 0.0736 0.244
Entamoeba histolytica hypothetical protein 0.0054 0.034 0.077
Loa Loa (eye worm) dihydrofolate reductase 0.01 0.0736 0.0736
Toxoplasma gondii phosphorylase family protein 0.0075 0.0518 0.1782
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus multilocularis peptidase Clp (S14 family) 0.0058 0.0374 0.0517
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0036 0.0128
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0014 0.002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0054 0.034 0.047
Toxoplasma gondii hypothetical protein 0.003 0.0138 0.0439
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0151 0.117 0.1158
Echinococcus granulosus death domain containing protein 0.0016 0.0017 0.0023
Plasmodium falciparum telomerase reverse transcriptase 0.0021 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0017
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0117 0.0879 0.3094
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.003 0.003
Schistosoma mansoni smad1 5 8 and 0.002 0.0048 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0036 0.0077
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.016 0.0145
Brugia malayi jmjC domain containing protein 0.0018 0.003 0.0016
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0084 0.0084
Brugia malayi uridine phosphorylase family protein 0.0075 0.0518 0.0505
Brugia malayi PHD-finger family protein 0.0018 0.003 0.0015
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0335 0.1085
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.003 0.0105
Trypanosoma brucei trypanothione reductase 0.0054 0.0335 0.1135
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0347 0.2842 1
Echinococcus granulosus cpg binding protein 0.0064 0.0424 0.0586
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0036 0.0188 0.2536
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Brugia malayi Ets-domain containing protein 0.0073 0.0505 0.0491
Loa Loa (eye worm) hypothetical protein 0.0039 0.0208 0.0208
Brugia malayi MH1 domain containing protein 0.002 0.0048 0.0034
Entamoeba histolytica hypothetical protein 0.0054 0.034 0.077
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0347 0.2842 1
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0188 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0133 0.0469
Loa Loa (eye worm) hypothetical protein 0.0053 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Giardia lamblia Fructose-bisphosphate aldolase 0.0268 0.2168 0.7268
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0017 0.0023
Brugia malayi Fucosyl transferase family protein 0.0177 0.1396 0.1383
Mycobacterium ulcerans hypothetical protein 0.0023 0.0073 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0021 0.0054 0.0189
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0246 0.1983 0.1972
Loa Loa (eye worm) hypothetical protein 0.0089 0.0635 0.0635
Echinococcus multilocularis lamin 0.0062 0.0404 0.0558
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.0042
Plasmodium vivax JmjC domain containing protein 0.0018 0.003 0.0055
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0335 0.0335
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.016 0.016
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0017 0.001
Brugia malayi Dihydrofolate reductase 0.01 0.0736 0.0723
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.003 0.003
Schistosoma mansoni Smad4 0.002 0.0048 0.0034
Leishmania major eukaryotic translation initiation factor-like protein 0.0065 0.0435 0.1532
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.003 0.0041
Schistosoma mansoni hypothetical protein 0.0054 0.034 0.0326
Schistosoma mansoni gabp alpha 0.0073 0.0505 0.0491
Entamoeba histolytica hypothetical protein 0.0054 0.034 0.077
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0036 0.005
Plasmodium falciparum purine nucleoside phosphorylase 0.0075 0.0518 0.1782
Brugia malayi hypoxia-induced factor 1 0.017 0.1335 0.1323
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0195 0.1547 0.2138
Giardia lamblia Rrm3p helicase 0.0055 0.035 0.1088
Brugia malayi jmjC domain containing protein 0.0104 0.0763 0.075
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0065 0.0435 0.0422
Plasmodium falciparum glutathione reductase 0.0054 0.0335 0.1135
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0075 0.0518 0.1668
Brugia malayi photoreceptor-specific nuclear receptor 0.0414 0.3417 0.3408
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0195 0.1547 0.1547
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Brugia malayi orphan nuclear receptor NR2E1 0.0195 0.1547 0.1535
Brugia malayi Uncoordinated protein 44 0.0016 0.0017 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.0763 0.1054
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0879 0.0879
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Schistosoma mansoni TGF-beta signal transducer Smad2 0.002 0.0048 0.0034
Mycobacterium tuberculosis Probable dehydrogenase 0.0122 0.0922 0.3068
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0132 0.0182
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0065 0.0435 0.1532
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Treponema pallidum pfs protein (pfs) 0.0075 0.0518 0.2261
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0039 0.0208 0.0194
Onchocerca volvulus 0.0411 0.3392 0.9927
Schistosoma mansoni steroid hormone receptor ad4bp 0.0414 0.3417 0.3408
Schistosoma mansoni protein phosphatase 2C 0.0018 0.003 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0036 0.0188 0.0662
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Brugia malayi nuclear hormone receptor family member nhr-6 0.0195 0.1547 0.1535
Brugia malayi nuclear receptor RXR 0.0219 0.1748 0.1736
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0087 0.062 0.2141
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Schistosoma mansoni hypothetical protein 0.0473 0.3925 0.3916
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0122 0.0922 0.3068
Brugia malayi nuclear receptor NHR-88 0.0195 0.1547 0.1535
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0219 0.1748 0.1736
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0058 0.0374 0.1258
Brugia malayi ecdysteroid receptor 0.0414 0.3417 0.3408
Loa Loa (eye worm) hypothetical protein 0.0287 0.2331 0.2331
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Brugia malayi jmjC domain containing protein 0.0018 0.003 0.0016
Echinococcus multilocularis lamin dm0 0.0062 0.0404 0.0558
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.003 0.0105
Trichomonas vaginalis set domain proteins, putative 0.0411 0.3391 0.3391
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0065 0.0435 0.0435
Plasmodium falciparum thioredoxin reductase 0.0019 0.0036 0.0077
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0036 0.0077
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.003 0.0041
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0335 0.1135
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Schistosoma mansoni dihydrofolate reductase 0.01 0.0736 0.0723
Brugia malayi MH2 domain containing protein 0.002 0.0048 0.0034
Brugia malayi N-terminal motif family protein 0.0252 0.2032 0.2021
Brugia malayi intermediate filament protein 0.0062 0.0404 0.039
Echinococcus granulosus bloom syndrome protein 0.0024 0.0084 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0292 0.2379 0.2379
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0036 0.0128
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0349 0.0335
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0084 0.0116
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0478 0.0465
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0138 0.0466
Echinococcus multilocularis dnaJ subfamily B 0.086 0.7238 1
Schistosoma mansoni uridine phosphorylase 0.0075 0.0518 0.0505
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0075 0.0518 0.1661
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0347 0.2842 1
Brugia malayi Pre-SET motif family protein 0.0053 0.033 0.0316
Schistosoma mansoni alpha(13)fucosyltransferase 0.0177 0.1396 0.1383
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Echinococcus multilocularis purine nucleoside phosphorylase 0.0287 0.2331 0.3221
Onchocerca volvulus 0.0062 0.0404 0.1182
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0195 0.1547 0.1535
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Toxoplasma gondii exonuclease III APE 0.0036 0.0188 0.0614
Brugia malayi tailless protein 0.0195 0.1547 0.1535
Loa Loa (eye worm) glutaminase 0.1183 1 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.003 0.0055
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0075 0.0518 0.1824
Schistosoma mansoni hypothetical protein 0.0018 0.003 0.0015
Echinococcus granulosus peptidase Clp S14 family 0.0058 0.0374 0.0517
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.003
Schistosoma mansoni RAR-like nuclear receptor 0.0414 0.3417 0.3408
Schistosoma mansoni methylthioadenosine phosphorylase 0.0075 0.0518 0.0505
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0151 0.117 0.1617
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0505 0.0505
Brugia malayi Steroid receptor seven-up type 2 0.0414 0.3417 0.3408
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0074 0.051 0.0704
Schistosoma mansoni alpha(13)fucosyltransferase 0.0177 0.1396 0.1383
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Brugia malayi MTAP 0.0075 0.0518 0.0505
Mycobacterium tuberculosis Hypothetical protein 0.0075 0.0518 0.1704
Brugia malayi MH2 domain containing protein 0.002 0.0048 0.0034
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0075 0.0518 0.1824
Onchocerca volvulus Protein ultraspiracle homolog 0.0414 0.3417 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0036 0.0188 0.0614
Loa Loa (eye worm) glutathione reductase 0.0054 0.0335 0.0335
Echinococcus granulosus microtubule associated protein 2 0.0746 0.6259 0.8647
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0136 0.1039 0.3462
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0362 0.2972 0.2962
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0414 0.3417 0.4721
Loa Loa (eye worm) translation initiation factor 4E 0.0065 0.0435 0.0435
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0084 0.007
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0087 0.062 0.2085
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0362 0.2972 0.2947
Echinococcus multilocularis purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0661 0.0647
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0219 0.1748 0.2414
Brugia malayi MH1 domain containing protein 0.002 0.0048 0.0034
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0058 0.0374 0.1215
Onchocerca volvulus 0.0195 0.1547 0.4528
Schistosoma mansoni hypothetical protein 0.086 0.7238 0.7234
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0018
Trypanosoma brucei uridine phosphorylase 0.0075 0.0518 0.1782
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0065 0.0435 0.0435
Brugia malayi Ets-domain containing protein 0.0073 0.0505 0.0491
Loa Loa (eye worm) hypothetical protein 0.0219 0.1748 0.1748
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0036 0.0188 0.0662
Echinococcus multilocularis mothers against decapentaplegic 5 0.002 0.0048 0.0066
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0362 0.2972 0.8697
Echinococcus multilocularis uridine phosphorylase 1 0.0075 0.0518 0.0716
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0195 0.1547 0.1535
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.003 0.0016
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0022 0.0031
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 0.2807
Echinococcus granulosus smad 0.002 0.0048 0.0066
Schistosoma mansoni uridine phosphorylase 0.0075 0.0518 0.0505
Chlamydia trachomatis AMP nucleosidase 0.0075 0.0518 0.7041
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0018 0.003 0.0015
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0252 0.2032 0.5947
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0036 0.0188 0.0662
Loa Loa (eye worm) hypothetical protein 0.0219 0.1748 0.1748
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 0.8621
Onchocerca volvulus Bile acid receptor homolog 0.0414 0.3417 1
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0036 0.0077
Giardia lamblia UPL-1 0.0075 0.0518 0.1661
Loa Loa (eye worm) PDE1B protein 0.0151 0.117 0.117
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0075 0.0518 0.1668
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0195 0.1547 0.4528
Trypanosoma brucei telomerase reverse transcriptase 0.0021 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Loa Loa (eye worm) hypothetical protein 0.0219 0.1748 0.1748
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0018 0.0004
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0023 0.0073 0.0213
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0138 0.0439
Brugia malayi nuclear receptor RXR 0.0195 0.1547 0.1535
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0016 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0242 0.0242
Echinococcus granulosus single minded 2 0.0041 0.0226 0.0312
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0362 0.2972 1
Mycobacterium ulcerans thymidylate synthase 0.0246 0.1983 0.1954
Schistosoma mansoni methylthioadenosine phosphorylase 0.0075 0.0518 0.0505
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0347 0.2842 1
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0075 0.0518 0.0484
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0122 0.0922 0.3068
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0347 0.2842 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0036 0.0022
Loa Loa (eye worm) hypothetical protein 0.003 0.0132 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0414 0.3417 0.3417
Entamoeba histolytica hypothetical protein 0.0054 0.034 0.077
Brugia malayi Pre-SET motif family protein 0.0361 0.2966 0.2956
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0065 0.0435 0.1489
Echinococcus granulosus TGF beta signal transducer SmadC 0.002 0.0048 0.0066
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0075 0.0518 0.1824
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.003 0.0041
Brugia malayi nuclear hormone receptor 0.0195 0.1547 0.1535
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0518 0.0518
Mycobacterium ulcerans endonuclease IV 0.0087 0.062 0.0586
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0036 0.0022
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0195 0.1547 0.2138
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0414 0.3417 0.3408
Schistosoma mansoni smad 0.002 0.0048 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0394 0.0394
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0075 0.0518 0.1824
Brugia malayi hypothetical protein 0.0138 0.1056 0.1043
Schistosoma mansoni hypothetical protein 0.0026 0.0104 0.0089
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0075 0.0522 0.0721
Treponema pallidum exodeoxyribonuclease (exoA) 0.0036 0.0188 0.0712
Leishmania major trypanothione reductase 0.0054 0.0335 0.118
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Brugia malayi steroid hormone receptor 0.0414 0.3417 0.3408
Schistosoma mansoni hypothetical protein 0.0473 0.3925 0.3916
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0065 0.0435 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0414 0.3417 0.3408
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0414 0.3417 0.3408
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.033 0.0316
Echinococcus multilocularis TGF beta signal transducer SmadC 0.002 0.0048 0.0066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0414 0.3417 0.4721
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus granulosus ecdysone induced protein 78C 0.0414 0.3417 0.4721
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 0.2194
Schistosoma mansoni purine nucleoside phosphorylase 0.0362 0.2972 0.2962
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0075 0.0518 0.1704
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0131 0.0997 0.3321
Toxoplasma gondii endonuclease IV APN 0.0087 0.062 0.2141
Echinococcus multilocularis ecdysone induced protein 78C 0.0414 0.3417 0.4721
Echinococcus granulosus purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Echinococcus multilocularis purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0188 0.0614
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0192 0.0192
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0136 0.1039 0.3494
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0414 0.3417 0.3408
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0414 0.3417 0.3408
Echinococcus multilocularis nuclear receptor nhr 48 0.0195 0.1547 0.2138
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0065 0.0435 0.1249
Loa Loa (eye worm) hypothetical protein 0.0075 0.0522 0.0522
Schistosoma mansoni nuclear receptor 0.0195 0.1547 0.1535
Leishmania major methylthioadenosine phosphorylase, putative 0.0075 0.0518 0.1824
Onchocerca volvulus 0.0414 0.3417 1
Loa Loa (eye worm) thymidylate synthase 0.0246 0.1983 0.1983
Onchocerca volvulus Alhambra homolog 0.0018 0.003 0.0087
Plasmodium vivax hypothetical protein, conserved 0.0018 0.003 0.0054
Plasmodium vivax telomerase reverse transcriptase, putative 0.0021 0.0054 0.0139
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0036 0.0077
Toxoplasma gondii RNA-directed DNA polymerase 0.0021 0.0054 0.0139
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0021 0.0054 0.0189
Treponema pallidum fructose-bisphosphate aldolase 0.0268 0.2168 1
Plasmodium falciparum phd finger protein, putative 0.0018 0.003 0.0054
Echinococcus multilocularis purine nucleoside phosphorylase 0.0362 0.2972 0.4106
Brugia malayi bHLH-PAS transcription factor 0.0041 0.0226 0.0212
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0075 0.0518 0.1668
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0055 0.035 0.1231
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0053 0.033 0.1117
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0036 0.0188 0.0152
Leishmania major hypothetical protein, conserved 0.0018 0.003 0.0105
Brugia malayi thymidylate synthase 0.0246 0.1983 0.1972
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0414 0.3417 0.3417
Echinococcus multilocularis FTZ F1 alpha 0.0414 0.3417 0.4721
Schistosoma mansoni cpg binding protein 0.0064 0.0424 0.041
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0055 0.035 0.1231
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0059 0.0158
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0036 0.0128
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.003
Schistosoma mansoni hypothetical protein 0.005 0.0308 0.0294
Echinococcus multilocularis jumonji domain containing protein 0.0025 0.0089 0.0123
Echinococcus granulosus Smad4 0.002 0.0048 0.0066
Schistosoma mansoni jumonji domain containing protein 0.0018 0.003 0.0016
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Echinococcus multilocularis microtubule associated protein 2 0.0746 0.6259 0.8647
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Loa Loa (eye worm) hypothetical protein 0.0414 0.3417 0.3417
Loa Loa (eye worm) hypothetical protein 0.0219 0.1748 0.1748
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.003 0.0055
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0122 0.0922 0.3102
Schistosoma mansoni ets-related 0.0223 0.1782 0.177
Schistosoma mansoni survival motor neuron protein 0.0055 0.0345 0.0331
Schistosoma mansoni alpha(13)fucosyltransferase 0.003 0.0133 0.0119
Loa Loa (eye worm) hypothetical protein 0.0268 0.2167 0.2167
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0268 0.2168 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0039 0.0208 0.0208
Loa Loa (eye worm) fli-1 protein 0.0223 0.1782 0.1782
Schistosoma mansoni coup transcription factor 0.0414 0.3417 0.3408
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0017 0.0002
Leishmania major nucleoside phosphorylase-like protein 0.0075 0.0518 0.1824
Echinococcus multilocularis Transcription initiation factor TFIID subunit 0.0045 0.0266 0.0368
Mycobacterium ulcerans epimerase 0.0023 0.0073 0.0037
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0036 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0195 0.1547 0.1535
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0074 0.051 0.0496
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0089 0.0635 1
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0075 0.0518 0.0518
Brugia malayi nuclear receptor NHR-88 0.0414 0.3417 0.3408
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.0335 0.0463
Schistosoma mansoni peptidase Clp (S14 family) 0.0089 0.0635 0.0621
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0347 0.2842 1
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0246 0.1983 0.6657
Brugia malayi CXXC zinc finger family protein 0.006 0.0394 0.0381
Onchocerca volvulus Alpha 1,3 fucosyltransferase homolog 0.0075 0.0522 0.1528
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0062 0.0404 0.0404
Echinococcus granulosus survival motor neuron protein 1 0.0268 0.2167 0.2994
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0036 0.0188 0.026
Schistosoma mansoni thyroid hormone receptor 0.0414 0.3417 0.3408
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0073 0.0197
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0036 0.0128
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0014 0.002
Echinococcus multilocularis survival motor neuron protein 1 0.0268 0.2167 0.2994
Brugia malayi Death domain containing protein 0.0016 0.0017 0.0002
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0075 0.0518 0.0518
Schistosoma mansoni retinoic acid receptor RXR 0.0414 0.3417 0.3408
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0074 0.051 0.0704
Schistosoma mansoni thyroid hormone receptor 0.0414 0.3417 0.3408
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0041 0.0026
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Echinococcus granulosus lamin 0.0062 0.0404 0.0558
Loa Loa (eye worm) hypothetical protein 0.0195 0.1547 0.1547
Loa Loa (eye worm) hypothetical protein 0.0219 0.1748 0.1748
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0195 0.1547 0.4528
Brugia malayi nuclear hormone receptor family member odr-7 0.0195 0.1547 0.1535
Toxoplasma gondii Purine nucleoside phosphorylase 0.0075 0.0518 0.1782
Schistosoma mansoni transcription factor LCR-F1 0.0054 0.034 0.0326
Brugia malayi Bromodomain containing protein 0.0018 0.003 0.0015
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0014 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0054 0.034 0.047
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0195 0.1547 0.2138
Brugia malayi hypothetical protein 0.0117 0.0879 0.0866
Schistosoma mansoni single-minded 0.0055 0.0349 0.0335
Loa Loa (eye worm) Smad1 0.002 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0414 0.3417 0.3408
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0077 0.0537 0.1572
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0089 0.0635 0.2136
Brugia malayi Smad1 0.002 0.0048 0.0034
Brugia malayi glutathione reductase 0.0054 0.0335 0.0321
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0075 0.0522 0.0721
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0014 0.0051
Brugia malayi exodeoxyribonuclease III family protein 0.0036 0.0188 0.0174
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.033 0.0456
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.003 0.0041
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0036 0.0077
Echinococcus granulosus Ankyrin 0.0016 0.0018 0.0025
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0055 0.0345 0.0331
Brugia malayi Nuclear hormone receptor-like 1 0.0219 0.1748 0.1736
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0635 0.2194
Loa Loa (eye worm) fucosyl transferase 0.0177 0.1396 0.1396
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0075 0.0518 0.1668
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0089 0.0635 0.0877
Brugia malayi Intermediate filament tail domain containing protein 0.0062 0.0404 0.039
Echinococcus granulosus jumonji domain containing protein 0.0025 0.0089 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0268 0.2168 0.2168
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0065 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0185 0.1458 0.1458
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0014 0.002

Activities

Activity type Activity value Assay description Source Reference
Log A (functional) = 1.26 Activity expressed by taste potency (taste intensity relative to sucrose on a mole/mole basis) ChEMBL. 7365747

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.