Detailed information for compound 1797666

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 290.487 | Formula: C18H28NS+
  • H donors: 0 H acceptors: 0 LogP: 7.34 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCC[n+]1c(C)sc2c1cccc2
  • InChi: 1S/C18H28NS/c1-3-4-5-6-7-8-9-12-15-19-16(2)20-18-14-11-10-13-17(18)19/h10-11,13-14H,3-9,12,15H2,1-2H3/q+1
  • InChiKey: WQKXCFJSGZWHPJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus calcium dependent secretion activator 1 0.0042 0.0142 0.0142
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0242 0.1491
Echinococcus multilocularis regulator of G protein signaling 0.0318 0.1528 0.1528
Trypanosoma brucei Aph-1 protein, putative 0.008 0.0336 0.5143
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0072 0.0294 0.0261
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0039 0.0041
Schistosoma mansoni coup transcription factor 0.0021 0.0039 0.0005
Echinococcus granulosus oxysterol binding protein 9 0.0042 0.0142 0.0142
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0052 0.0192 0.5246
Leishmania major hypothetical protein, conserved 0.0024 0.0051 0.0837
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1442 0.7161 0.7151
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0255 0.1212 0.1183
Echinococcus granulosus N chimaerin 0.0062 0.0243 0.0243
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Schistosoma mansoni zinc finger protein 0.0042 0.0142 0.0109
Onchocerca volvulus 0.0042 0.0142 0.0754
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0042 0.0142 0.0724
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0039 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0242 0.1491
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0412 0.2534
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Entamoeba histolytica PH domain containing protein 0.0042 0.0142 0.0724
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0722 0.0691
Echinococcus granulosus expressed protein 0.0318 0.1528 0.1528
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0039 0.0039
Brugia malayi Regulator of G protein signaling domain containing protein 0.0318 0.1528 0.2124
Trypanosoma cruzi Aph-1 protein, putative 0.008 0.0336 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0184 0.0184
Brugia malayi Pleckstrin Homology Domain 0.0103 0.0452 0.0619
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0121 0.0121
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0039 0.0005
Schistosoma mansoni hypothetical protein 0.0158 0.0727 0.0695
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0039 0.0041
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0586 0.0554
Onchocerca volvulus 0.0042 0.0142 0.0754
Echinococcus multilocularis calcium dependent secretion activator 1 0.0042 0.0142 0.0142
Brugia malayi hypothetical protein 0.0318 0.1528 0.2124
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0039 0.0005
Echinococcus granulosus serine:threonine protein kinase N2 0.0096 0.0412 0.0412
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0039 0.0039
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0185
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0142 0.6827
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.1171 0.1141
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0042 0.0142 0.6827
Echinococcus granulosus dynamin 1 0.0042 0.0142 0.0142
Entamoeba histolytica ARF GTPase activating protein, putative 0.0042 0.0142 0.0724
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Brugia malayi Stress-activated protein kinase jnk-1 0.0255 0.1212 0.1682
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0042 0.0142 0.3581
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Schistosoma mansoni protein kinase C 0.0062 0.0243 0.021
Brugia malayi regulator of G-protein signaling egl-10 0.0318 0.1528 0.2124
Loa Loa (eye worm) zinc finger protein 0.0062 0.0244 0.0211
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Schistosoma mansoni transient receptor potential channel 0.0065 0.0259 0.0226
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2008 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Echinococcus multilocularis Oxysterol binding protein 11 0.0042 0.0142 0.0142
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0034 0.5
Trypanosoma cruzi PB1 domain containing protein, putative 0.0062 0.0244 0.6947
Echinococcus granulosus regulator of G protein signaling 7 0.0318 0.1528 0.1528
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Schistosoma mansoni transient receptor potential channel 4 0.0098 0.0426 0.0394
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0042 0.0142 0.0142
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0042 0.0142 0.0754
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis regulator of G protein signaling 3 0.0318 0.1528 0.1528
Echinococcus multilocularis rac serine:threonine kinase 0.0052 0.0192 0.0192
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1123 0.5566 0.5566
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0178 0.0178
Plasmodium falciparum PH domain-containing protein, putative 0.0042 0.0142 0.6827
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0039 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0247 0.1171 0.1624
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0072 0.0293 0.0261
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Echinococcus multilocularis oxysterol binding protein 9 0.0042 0.0142 0.0142
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Trichomonas vaginalis hypothetical protein 0.0042 0.0142 0.0724
Onchocerca volvulus 0.0042 0.0142 0.0754
Brugia malayi Protein kinase domain containing protein 0.0137 0.0621 0.0855
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0042 0.0142 0.0724
Brugia malayi Protein kinase domain containing protein 0.0072 0.0293 0.0397
Brugia malayi Oxysterol binding protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0096 0.0412 0.038
Loa Loa (eye worm) hypothetical protein 0.0062 0.0244 0.0211
Echinococcus granulosus axis inhibition protein axin 0.0318 0.1528 0.1528
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0042 0.0142 0.0142
Loa Loa (eye worm) RasGEF domain-containing protein 0.0062 0.0243 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.0117 0.0117
Brugia malayi nuclear receptor NHR-88 0.0021 0.0039 0.0041
Echinococcus multilocularis partitioning defective protein 6 0.0062 0.0244 0.0244
Brugia malayi MH2 domain containing protein 0.013 0.0586 0.0806
Schistosoma mansoni growth factor receptor-bound protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0158 0.0725 0.0694
Brugia malayi Protein kinase c protein 2 0.0072 0.0293 0.0397
Echinococcus granulosus pleckstrin y domain containing family A 0.0042 0.0142 0.0142
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Echinococcus granulosus oxysterol binding protein 3 0.0042 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0108 0.0475 0.0442
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0116 0.0116
Brugia malayi diacylglycerol kinase 0.0062 0.0243 0.0327
Onchocerca volvulus Protein melted homolog 0.0042 0.0142 0.0754
Trypanosoma brucei protein kinase, putative 0.0052 0.0192 0.2698
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0042 0.0142 0.0754
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0042 0.0142 0.0142
Brugia malayi Calcitonin receptor-like protein seb-1 0.0158 0.0725 0.1001
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0242 0.0209
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.0117 0.0117
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Schistosoma mansoni protein kinase C mu 0.0072 0.0293 0.0261
Loa Loa (eye worm) inositol-1 0.0037 0.0121 0.0087
Entamoeba histolytica hypothetical protein 0.0062 0.0243 0.1401
Loa Loa (eye worm) hypothetical protein 0.0024 0.0051 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Brugia malayi hypothetical protein 0.0294 0.1408 0.1956
Schistosoma mansoni oxysterol-binding protein 1 0.0042 0.0142 0.0109
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0052 0.0192 0.5246
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0039 0.0041
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0318 0.1528 0.15
Echinococcus multilocularis beta 1 syntrophin 0.0042 0.0142 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Schistosoma mansoni hypothetical protein 0.0108 0.0475 0.0442
Echinococcus multilocularis serine:threonine protein kinase 38 0.0096 0.0412 0.0412
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0042 0.0142 0.0142
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0042 0.0142 0.6827
Echinococcus multilocularis dynamin 1 0.0042 0.0142 0.0142
Echinococcus multilocularis N chimaerin 0.0062 0.0243 0.0243
Brugia malayi MAX-1A 0.0042 0.0142 0.0185
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Echinococcus granulosus oxysterol binding protein 1 0.0042 0.0142 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0062 0.0243 0.021
Echinococcus multilocularis regulator of G protein signaling 3 0.0318 0.1528 0.1528
Onchocerca volvulus 0.0103 0.0452 0.3017
Schistosoma mansoni centaurin alpha 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0086 0.0362 0.2197
Schistosoma mansoni hypothetical protein 0.0414 0.201 0.1983
Echinococcus multilocularis serine threonine protein kinase 0.0096 0.0412 0.0412
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0052 0.0192 0.5246
Brugia malayi Variant SH3 domain containing protein 0.0042 0.0142 0.0185
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0034 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.1212 0.1183
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0039 0.0005
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0062 0.0243 0.0243
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Brugia malayi Variant SH3 domain containing protein 0.0062 0.0243 0.0327
Echinococcus granulosus cpg binding protein 0.0031 0.0087 0.0087
Schistosoma mansoni goodpasture antigen-binding protein 0.0042 0.0142 0.0109
Brugia malayi gamma-secretase subunit aph-1 0.0206 0.0966 0.1338
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus multilocularis actin binding protein anillin 0.0042 0.0142 0.0142
Brugia malayi Protein kinase domain containing protein 0.0072 0.0294 0.0398
Loa Loa (eye worm) hypothetical protein 0.0033 0.01 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Brugia malayi Uncoordinated protein 104 0.0042 0.0142 0.0185
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0039 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0051 0.1109
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0042 0.0142 0.0142
Echinococcus multilocularis transient receptor potential ion channel A 0.0095 0.041 0.041
Brugia malayi p70 ribosomal S6 kinase beta 0.0096 0.0412 0.0563
Echinococcus multilocularis oxysterol binding protein 3 0.0042 0.0142 0.0142
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0184 0.0184
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0184 0.0184
Echinococcus multilocularis cytohesin 1 0.0042 0.0142 0.0142
Echinococcus granulosus dnaJ subfamily B 0.0414 0.201 0.201
Brugia malayi Oxysterol-binding protein 0.0042 0.0142 0.0185
Trypanosoma brucei rac serine-threonine kinase, putative 0.0137 0.0621 1
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0042 0.0142 0.0724
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Schistosoma mansoni z-protein (S1r protein) 0.0318 0.1528 0.15
Onchocerca volvulus 0.0062 0.0244 0.1497
Plasmodium falciparum oxysterol-binding protein, putative 0.0042 0.0142 0.6827
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0116 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0051 0.0582
Echinococcus granulosus protein TFG 0.0062 0.0244 0.0244
Echinococcus granulosus protein kinase c epsilon type 0.0157 0.0722 0.0722
Echinococcus multilocularis gamma secretase subunit aph 1 0.0206 0.0966 0.0966
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0318 0.1528 0.15
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.021 0.4644
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0242 0.9906
Brugia malayi diacylglycerol kinase 0.0062 0.0243 0.0327
Mycobacterium ulcerans glutaminase 0.0298 0.1428 1
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Entamoeba histolytica hypothetical protein 0.0052 0.0192 0.106
Trichomonas vaginalis centaurin gamma, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0042 0.0142 0.0142
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0039 0.0039
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Leishmania major hypothetical protein, conserved 0.0042 0.0142 0.5156
Echinococcus granulosus protein kinase c eta type 0.0062 0.0243 0.0243
Schistosoma mansoni dynamin 0.0042 0.0142 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus GPCR family 2 0.005 0.0184 0.0184
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0042 0.0142 0.3581
Onchocerca volvulus Protein TFG homolog 0.0062 0.0244 0.1497
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0042 0.0142 0.0724
Brugia malayi Variant SH3 domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Echinococcus granulosus pdz domain containing protein 0.0042 0.0142 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus unc 13 munc13 0.0062 0.0243 0.0243
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) oxysterol binding protein 0.0042 0.0142 0.0109
Trypanosoma cruzi Aph-1 protein, putative 0.008 0.0336 1
Entamoeba histolytica hypothetical protein, conserved 0.0062 0.0244 0.1404
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0096 0.0412 0.0412
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0042 0.0142 0.0109
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0072 0.0293 0.0293
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus protein kinase C gamma type 0.0096 0.0412 0.0412
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0034 0.0034
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0096 0.0412 0.0412
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0039 0.0039
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Plasmodium falciparum calcium-dependent protein kinase 7 0.0052 0.0192 1
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0096 0.0412 0.0412
Brugia malayi probable spectrin beta chain 0.0042 0.0142 0.0185
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0157 0.0722 0.0691
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Trichomonas vaginalis centaurin/arf, putative 0.0042 0.0142 0.0724
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0072 0.0293 0.0397
Echinococcus multilocularis unc 13 (munc13) 0.0062 0.0243 0.0243
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Schistosoma mansoni hypothetical protein 0.0036 0.0116 0.0083
Brugia malayi Cytohesin 3 0.0042 0.0142 0.0185
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0037 0.0117 0.0083
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0052 0.0192 1
Brugia malayi hypothetical protein 0.0024 0.0051 0.0059
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Trichomonas vaginalis alpha chimerin, putative 0.0042 0.0142 0.0724
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0121 0.0583
Trichomonas vaginalis kinesin light chain, putative 0.0042 0.0142 0.0724
Echinococcus granulosus gamma secretase subunit aph 1 0.0206 0.0966 0.0966
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0121 0.0583
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0039 0.0041
Trypanosoma cruzi Protein kinase B 0.0052 0.0192 0.5246
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0042 0.0142 0.3581
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Onchocerca volvulus 0.0029 0.0079 0.0296
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0039 0.0005
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0206 0.0966 0.0936
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0293 0.0261
Entamoeba histolytica hypothetical protein 0.0318 0.1528 1
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0039 0.0005
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0096 0.0412 0.038
Echinococcus granulosus DCC interacting protein 13 beta 0.0042 0.0142 0.0142
Leishmania major hypothetical protein, conserved 0.0042 0.0142 0.5156
Schistosoma mansoni serine/threonine kinase 0.0096 0.0412 0.038
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0242 0.549
Echinococcus granulosus Pleckstrin y 0.0042 0.0142 0.0142
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0586 0.0554
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0192 0.5246
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0042 0.0142 0.0142
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1123 0.5566 0.5551
Brugia malayi Cadps2 protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni goodpasture antigen-binding protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) uncoordinated protein 104 0.0042 0.0142 0.0109
Toxoplasma gondii hypothetical protein 0.0042 0.0142 0.2857
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0039 0.0005
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0052 0.0192 0.5246
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Brugia malayi RhoGAP domain containing protein 0.0062 0.0243 0.0327
Trichomonas vaginalis protein transport protein sec7, putative 0.0042 0.0142 0.0724
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0039 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Trypanosoma cruzi PB1 domain containing protein, putative 0.0062 0.0244 0.6947
Brugia malayi Inositol-1 0.0037 0.0121 0.0156
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Brugia malayi Plekhf2 protein 0.0042 0.0142 0.0185
Brugia malayi protein kinase C3,putative 0.0915 0.452 0.6307
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0051 0.0582
Schistosoma mansoni cell polarity protein 0.0062 0.0244 0.0211
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0103 0.0452 0.0419
Schistosoma mansoni transient receptor potential channel 0.0065 0.0259 0.0226
Loa Loa (eye worm) cytohesin 3 0.0042 0.0142 0.0109
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.0259 0.0259
Schistosoma mansoni hypothetical protein 0.0158 0.0727 0.0695
Brugia malayi Dynamin 0.0042 0.0142 0.0185
Schistosoma mansoni rho gtpase activating protein 0.0042 0.0142 0.0109
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0052 0.0192 0.106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0178 0.0178
Brugia malayi hypothetical protein 0.0036 0.0116 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0096 0.0412 0.038
Loa Loa (eye worm) AGC/NDR protein kinase 0.0096 0.0412 0.038
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0034 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Brugia malayi ecdysteroid receptor 0.0021 0.0039 0.0041
Brugia malayi A-kinase anchor protein 10, precursor 0.0318 0.1528 0.2124
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0192 0.5246
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0318 0.1528 0.15
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.2883
Echinococcus multilocularis DCC interacting protein 13 beta 0.0042 0.0142 0.0142
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0096 0.0412 0.038
Entamoeba histolytica diacylglycerol kinase, putative 0.0062 0.0243 0.1401
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Toxoplasma gondii diacylglycerol kinase, putative 0.0062 0.0243 0.5531
Echinococcus granulosus Rac GTPase activating protein 1 0.0062 0.0243 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0039 0.0041
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0042 0.0142 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Loa Loa (eye worm) hypothetical protein 0.0103 0.0452 0.0419
Echinococcus multilocularis axis inhibition protein axin 0.0318 0.1528 0.1528
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Echinococcus granulosus axis inhibition protein axin 0.0318 0.1528 0.1528
Onchocerca volvulus 0.0062 0.0243 0.1494
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0412 0.2534
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Echinococcus granulosus myotubularin protein 13 0.0103 0.0452 0.0452
Echinococcus granulosus regulator of G protein signaling 7 0.0318 0.1528 0.1528
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Schistosoma mansoni cpg binding protein 0.0031 0.0087 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0039 0.0041
Loa Loa (eye worm) PAR-6 protein 0.0062 0.0244 0.0211
Loa Loa (eye worm) raf kinase 0.0062 0.0243 0.021
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0121 0.0583
Loa Loa (eye worm) RGS-3 protein 0.0318 0.1528 0.15
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0101 0.5
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0192 0.0159
Brugia malayi RhoGAP domain containing protein 0.0062 0.0243 0.0327
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0098 0.0426 0.0394
Echinococcus granulosus beta 1 syntrophin 0.0042 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0042 0.0142 0.0109
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.2883
Echinococcus multilocularis expressed protein 0.0318 0.1528 0.1528
Schistosoma mansoni serine/threonine protein kinase 0.2008 1 1
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Brugia malayi Regulator of G protein signaling domain containing protein 0.0318 0.1528 0.2124
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0079 0.0046
Echinococcus multilocularis cpg binding protein 0.0031 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0039 0.0041
Entamoeba histolytica p21-activated kinase 0.0052 0.0192 0.106
Onchocerca volvulus 0.0042 0.0142 0.0754
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Brugia malayi Partitioning defective-6 homolog alpha 0.0062 0.0244 0.0327
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1123 0.5566 0.5551
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0052 0.0192 0.5246
Entamoeba histolytica protein kinase, putative 0.0096 0.0412 0.2534
Echinococcus granulosus Diacylglycerol kinase theta 0.0062 0.0243 0.0243
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0977 0.4831 0.4813
Loa Loa (eye worm) hypothetical protein 0.0158 0.0725 0.0694
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Echinococcus multilocularis raf serine:threonine protein kinase 0.0062 0.0243 0.0243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0039 0.0005
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Schistosoma mansoni atypical protein kinase C 0.1062 0.5259 0.5243
Onchocerca volvulus 0.0042 0.0142 0.0754
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0158 0.0725 0.1001
Entamoeba histolytica PH domain containing protein 0.0042 0.0142 0.0724
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0039 0.0041
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0242 0.0242
Echinococcus granulosus serine/threonine protein kinase 0.0052 0.0192 0.0192
Echinococcus multilocularis GPCR, family 2 0.005 0.0184 0.0184
Trypanosoma cruzi NIMA-related kinase, putative 0.0052 0.0192 0.5246
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0039 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0142 0.6827
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0039 0.0039
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0042 0.0142 0.0142
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0051 0.1109
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Brugia malayi C1-like domain containing protein 0.0072 0.0293 0.0397
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0242 0.0242
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0042 0.0142 0.6827
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0062 0.0243 0.0243
Schistosoma mansoni dynamin 0.0042 0.0142 0.0109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0178 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trichomonas vaginalis centaurin beta, putative 0.0042 0.0142 0.0724
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0052 0.0192 0.4185
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0051 0.1109
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0178 0.0178
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0062 0.0243 0.021
Schistosoma mansoni diacylglycerol kinase theta 0.0062 0.0243 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0722 0.0691
Echinococcus granulosus c-Jun N-terminal kinases 0.0255 0.1212 0.1212
Loa Loa (eye worm) hypothetical protein 0.0294 0.1408 0.1379
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0042 0.0142 0.0142
Echinococcus granulosus Pleckstrin y 0.0042 0.0142 0.0142
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0062 0.0243 0.021
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.415
Entamoeba histolytica PH domain containing protein 0.0042 0.0142 0.0724
Echinococcus granulosus regulator of G protein signaling 3 0.0318 0.1528 0.1528
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0121 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0178 0.0235
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0039 0.0005
Onchocerca volvulus 0.0042 0.0142 0.0754
Echinococcus granulosus Oxysterol binding protein 11 0.0042 0.0142 0.0142
Echinococcus multilocularis pleckstrin y domain containing family A 0.0042 0.0142 0.0142
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0142 0.0724
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Brugia malayi CXXC zinc finger family protein 0.0029 0.0079 0.0097
Echinococcus granulosus transient receptor potential ion channel A 0.0095 0.041 0.041
Schistosoma mansoni axis inhibition protein axin 0.0318 0.1528 0.15
Echinococcus multilocularis oxysterol binding protein 1 0.0042 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.2008 1 1
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0042 0.0142 0.0142
Trichomonas vaginalis protein transport protein sec7, putative 0.0042 0.0142 0.0724
Echinococcus granulosus Pleckstrin y 0.0042 0.0142 0.0142
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Brugia malayi PXA domain containing protein 0.0318 0.1528 0.2124
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Schistosoma mansoni zinc finger protein 0.0042 0.0142 0.0109
Echinococcus granulosus GRB2 associated binding protein 3 0.0042 0.0142 0.0142
Schistosoma mansoni unc-13 (munc13) 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Echinococcus multilocularis protein kinase c epsilon type 0.0157 0.0722 0.0722
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Leishmania major hypothetical protein, conserved 0.0062 0.0244 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0039 0.0041
Brugia malayi Latrophilin receptor protein 2 0.005 0.0184 0.0244
Echinococcus multilocularis transient receptor potential gamma protein 0.0098 0.0426 0.0426
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0293 0.0261
Brugia malayi Dynamin 0.0042 0.0142 0.0185
Echinococcus granulosus raf serine:threonine protein kinase 0.0062 0.0243 0.0243
Brugia malayi steroid hormone receptor 0.0021 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0039 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Schistosoma mansoni hypothetical protein 0.0062 0.0243 0.021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0243 0.021
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1442 0.7161 1
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0042 0.0142 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0121 0.23
Entamoeba histolytica hypothetical protein 0.0318 0.1528 1
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0192 0.0159
Echinococcus multilocularis protein TFG 0.0062 0.0244 0.0244
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0096 0.0412 0.0412
Schistosoma mansoni syntrophin 0.0042 0.0142 0.0109
Loa Loa (eye worm) AGC/PKN protein kinase 0.0096 0.0412 0.038
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0157 0.0722 0.0722
Echinococcus multilocularis regulator of G protein signaling 7 0.0318 0.1528 0.1528
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0039 0.0005
Brugia malayi Ras association domain family 1 isoform A 0.0062 0.0243 0.0327
Brugia malayi RhoGEF domain containing protein 0.0062 0.0243 0.0327
Brugia malayi regulator of G-protein signaling rgs-7 0.0318 0.1528 0.2124
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0096 0.0412 0.0412
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0052 0.0192 0.7552
Brugia malayi glutaminase DH11.1 0.0298 0.1428 0.1983
Echinococcus granulosus protein kinase c iota type 0.1 0.4949 0.4949
Schistosoma mansoni serine/threonine protein kinase 0.1442 0.7161 0.7151
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0255 0.1212 0.1212
Echinococcus multilocularis Rho GTPase activating protein 24 0.0042 0.0142 0.0142
Brugia malayi Hr1 repeat family protein 0.0096 0.0412 0.0563
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0042 0.0142 0.6827
Loa Loa (eye worm) PXA domain-containing protein 0.0318 0.1528 0.15
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0242 0.1491
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0042 0.0142 0.0142
Brugia malayi Protein kinase domain containing protein 0.0096 0.0412 0.0563
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0062 0.0243 0.021
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0242 0.0209
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0318 0.1528 1
Trypanosoma brucei PB1 domain containing protein, putative 0.0062 0.0244 0.3573
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0039 0.0005
Entamoeba histolytica protein kinase, putative 0.0137 0.0621 0.393
Toxoplasma gondii protein kinase domain-containing protein 0.0052 0.0192 0.4185
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0178 0.0144
Brugia malayi latrophilin 2 splice variant baaae 0.0108 0.0475 0.0651
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Echinococcus multilocularis geminin 0.0158 0.0727 0.0727
Schistosoma mansoni protein kinase C mu 0.0062 0.0243 0.021
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0052 0.0192 0.5246
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1123 0.5566 0.5566
Echinococcus multilocularis Regulator of G protein signaling 20 0.0318 0.1528 0.1528
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0052 0.0192 0.2698
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0318 0.1528 0.1528
Brugia malayi PXA domain containing protein 0.0318 0.1528 0.2124
Trichomonas vaginalis glutaminase, putative 0.0298 0.1428 0.9327
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0039 0.0041
Brugia malayi hypothetical protein 0.0318 0.1528 0.2124
Loa Loa (eye worm) glutaminase 2 0.0298 0.1428 0.1399
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0039 0.0039
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Onchocerca volvulus 0.0072 0.0294 0.1864
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Entamoeba histolytica hypothetical protein 0.0052 0.0192 0.106
Echinococcus multilocularis Rac GTPase activating protein 1 0.0062 0.0243 0.0243
Entamoeba histolytica protein kinase, putative 0.0137 0.0621 0.393
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0042 0.0142 0.0142
Echinococcus granulosus NDR protein kinase 0.0096 0.0412 0.0412
Schistosoma mansoni glutaminase 0.0298 0.1428 0.1399
Echinococcus granulosus transient receptor potential gamma protein 0.0098 0.0426 0.0426
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0039 0.0039
Toxoplasma gondii AGC kinase 0.0096 0.0412 1
Leishmania major folate/biopterin transporter, putative 0.0052 0.0192 0.7552
Echinococcus multilocularis serine:threonine protein kinase N2 0.0096 0.0412 0.0412
Brugia malayi Protein kinase domain containing protein 0.0096 0.0412 0.0563
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0142 0.0724
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0062 0.0243 0.0243
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0062 0.0243 0.0243
Schistosoma mansoni oxysterol-binding protein 1 0.0042 0.0142 0.0109
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0039 0.0005
Schistosoma mansoni inositol monophosphatase 0.0037 0.0121 0.0087
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0052 0.0192 0.2698
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0039 0.0039
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Brugia malayi protein kinase C II. 0.0157 0.0722 0.0997
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0039 0.0005
Entamoeba histolytica protein kinase, putative 0.0096 0.0412 0.2534
Loa Loa (eye worm) glutaminase 0.0298 0.1428 0.1399
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.1483
Schistosoma mansoni unc-13 (munc13) 0.0062 0.0243 0.021
Echinococcus granulosus Rho GTPase activating protein 24 0.0042 0.0142 0.0142
Echinococcus granulosus geminin 0.0158 0.0727 0.0727
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0039 0.0041
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0101 0.3244
Trichomonas vaginalis centaurin alpha, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis Diacylglycerol kinase theta 0.0062 0.0243 0.0243
Loa Loa (eye worm) syntrophin-1 0.0042 0.0142 0.0109
Echinococcus multilocularis Pleckstrin y 0.0042 0.0142 0.0142
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0184 0.0151
Schistosoma mansoni diacylglycerol kinase theta 0.0062 0.0243 0.021
Echinococcus granulosus G protein coupled receptor kinase 1 0.169 0.8405 0.8405
Echinococcus multilocularis axis inhibition protein axin 0.0318 0.1528 0.1528
Loa Loa (eye worm) Plekhf2 protein 0.0042 0.0142 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0039 0.0041
Plasmodium vivax PH domain containing protein 0.0042 0.0142 0.6827
Echinococcus multilocularis Pleckstrin y 0.0042 0.0142 0.0142
Toxoplasma gondii phosphatidylinositol transfer protein 0.0042 0.0142 0.2857
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0039 0.0041
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0039 0.0039
Trypanosoma brucei PH domain containing protein, putative 0.0042 0.0142 0.1842
Toxoplasma gondii AtPH1 family protein 0.0042 0.0142 0.2857
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1123 0.5566 0.777
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0116 0.0083
Schistosoma mansoni vav2 0.0103 0.0452 0.0419
Trichomonas vaginalis centaurin/arf, putative 0.0042 0.0142 0.0724
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0096 0.0412 0.0412
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0318 0.1528 0.1528
Echinococcus multilocularis myotubularin protein 13 0.0103 0.0452 0.0452
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0318 0.1528 0.15
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0412 0.2534
Schistosoma mansoni myotubularin-related protein 0.0042 0.0142 0.0109
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0052 0.0192 0.7552
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0051 0.0464
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.0151
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0096 0.0412 0.038
Toxoplasma gondii Oxysterol-binding protein 0.0042 0.0142 0.2857
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0178 0.0144
Echinococcus multilocularis GRB2 associated binding protein 3 0.0042 0.0142 0.0142
Loa Loa (eye worm) AGC/AKT protein kinase 0.0137 0.0621 0.0589
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0039 0.0041
Echinococcus multilocularis pdz domain containing protein 0.0042 0.0142 0.0142
Echinococcus multilocularis Ras associated and pleckstrin y 0.0042 0.0142 0.0142
Echinococcus multilocularis protein kinase c eta type 0.0062 0.0243 0.0243
Echinococcus multilocularis beta adrenergic receptor kinase 0.2008 1 1
Echinococcus multilocularis G protein coupled receptor kinase 1 0.169 0.8405 0.8405
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) PH domain-containing protein 0.0042 0.0142 0.0109
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0051 0.0299
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0042 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Schistosoma mansoni cpg binding protein 0.0029 0.0079 0.0046
Brugia malayi Transient-receptor-potential like protein 0.0037 0.0117 0.015
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0042 0.0142 0.0142
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0042 0.0142 0.0109
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0052 0.0192 0.5246
Echinococcus granulosus Protein kinase C brain isozyme 0.0157 0.0722 0.0722
Leishmania major serine/threonine-protein kinase a, putative 0.0052 0.0192 0.7552
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Schistosoma mansoni gamma-secretase subunit aph-1 0.0206 0.0966 0.0936
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0052 0.0192 0.2698
Echinococcus granulosus regulator of G protein signaling 3 0.0318 0.1528 0.1528
Echinococcus granulosus cytohesin 1 0.0042 0.0142 0.0142
Leishmania major protein kinase, putative 0.0052 0.0192 0.7552
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0178 0.0144
Schistosoma mansoni axis inhibition protein axin 0.0318 0.1528 0.15
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0142 0.6827
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0039 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0722 0.0691
Echinococcus multilocularis dnaJ subfamily B 0.0414 0.201 0.201
Schistosoma mansoni rac gtpase activating protein 0.0062 0.0243 0.021
Echinococcus multilocularis regulator of G protein signaling 7 0.0318 0.1528 0.1528
Brugia malayi hypothetical protein 0.0042 0.0142 0.0185
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Leishmania major protein kinase, putative 0.0052 0.0192 0.7552
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0052 0.0192 0.2698
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0185
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Brugia malayi nuclear hormone receptor 0.0021 0.0039 0.0041
Schistosoma mansoni cpg binding protein 0.0031 0.0087 0.0054
Echinococcus multilocularis protein kinase c iota type 0.1 0.4949 0.4949
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0039 0.0005
Onchocerca volvulus outspread protein homolog 0.0042 0.0142 0.0754
Toxoplasma gondii hypothetical protein 0.0042 0.0142 0.2857
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.0259 0.0259
Brugia malayi Syntrophin-1 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0242 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0121 0.0625
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Onchocerca volvulus Putative zinc finger protein 0.0042 0.0142 0.0754
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0042 0.0142 0.0109
Schistosoma mansoni inositol monophosphatase 0.0037 0.0121 0.0087
Brugia malayi TBC domain containing protein 0.0042 0.0142 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0184 0.0244
Echinococcus granulosus Regulator of G protein signaling 20 0.0318 0.1528 0.1528
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0034 0.5
Entamoeba histolytica hypothetical protein 0.0318 0.1528 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Onchocerca volvulus 0.0062 0.0243 0.1494
Loa Loa (eye worm) rho-GTPase-activating 0.0042 0.0142 0.0109
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0142 0.0724
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0039 0.0005
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0042 0.0142 0.0142
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0121 0.0583
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0039 0.0005
Entamoeba histolytica diacylglycerol kinase, putative 0.0062 0.0243 0.1401
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Schistosoma mansoni transient receptor potential channel 0.0098 0.0426 0.0394
Trypanosoma cruzi NIMA-related kinase, putative 0.0052 0.0192 0.5246
Echinococcus multilocularis Pleckstrin y 0.0042 0.0142 0.0142
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0072 0.0293 0.0293
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0184 0.0184
Echinococcus multilocularis serine:threonine protein kinase N2 0.0096 0.0412 0.0412
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.0259 0.0259
Onchocerca volvulus 0.0294 0.1408 1
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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