Detailed information for compound 1798768

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 276.46 | Formula: C17H26NS+
  • H donors: 0 H acceptors: 0 LogP: 6.8 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCC[n+]1c(C)sc2c1cccc2
  • InChi: 1S/C17H26NS/c1-3-4-5-6-7-8-11-14-18-15(2)19-17-13-10-9-12-16(17)18/h9-10,12-13H,3-8,11,14H2,1-2H3/q+1
  • InChiKey: VHIJPDTUGCOTML-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus dnaJ subfamily B 0.0414 0.201 0.201
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Schistosoma mansoni cpg binding protein 0.0031 0.0087 0.0054
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Echinococcus granulosus Protein kinase C brain isozyme 0.0157 0.0722 0.0722
Brugia malayi Protein kinase domain containing protein 0.0096 0.0412 0.0563
Brugia malayi ecdysteroid receptor 0.0021 0.0039 0.0041
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0039 0.0005
Echinococcus granulosus G protein coupled receptor kinase 1 0.169 0.8405 0.8405
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0142 0.0724
Schistosoma mansoni zinc finger protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Schistosoma mansoni hypothetical protein 0.0108 0.0475 0.0442
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Schistosoma mansoni transient receptor potential channel 0.0065 0.0259 0.0226
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0039 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Entamoeba histolytica protein kinase, putative 0.0137 0.0621 0.393
Brugia malayi RhoGAP domain containing protein 0.0062 0.0243 0.0327
Schistosoma mansoni atypical protein kinase C 0.1062 0.5259 0.5243
Loa Loa (eye worm) zinc finger protein 0.0062 0.0244 0.0211
Entamoeba histolytica PH domain containing protein 0.0042 0.0142 0.0724
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0318 0.1528 0.15
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0052 0.0192 0.2698
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0042 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0412 0.2534
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0096 0.0412 0.038
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0185
Brugia malayi glutaminase DH11.1 0.0298 0.1428 0.1983
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0121 0.0625
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus multilocularis DCC interacting protein 13 beta 0.0042 0.0142 0.0142
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0116 0.0116
Brugia malayi hypothetical protein 0.0294 0.1408 0.1956
Brugia malayi hypothetical protein 0.0024 0.0051 0.0059
Brugia malayi Protein kinase domain containing protein 0.0096 0.0412 0.0563
Echinococcus multilocularis cytohesin 1 0.0042 0.0142 0.0142
Brugia malayi hypothetical protein 0.0318 0.1528 0.2124
Trichomonas vaginalis protein transport protein sec7, putative 0.0042 0.0142 0.0724
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0039 0.0005
Echinococcus multilocularis serine:threonine protein kinase N2 0.0096 0.0412 0.0412
Brugia malayi C1-like domain containing protein 0.0072 0.0293 0.0397
Loa Loa (eye worm) AGC/AKT protein kinase 0.0137 0.0621 0.0589
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0042 0.0142 0.3581
Brugia malayi diacylglycerol kinase 0.0062 0.0243 0.0327
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0101 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Trypanosoma brucei rac serine-threonine kinase, putative 0.0137 0.0621 1
Echinococcus granulosus dynamin 1 0.0042 0.0142 0.0142
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0072 0.0293 0.0261
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni inositol monophosphatase 0.0037 0.0121 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus expressed protein 0.0318 0.1528 0.1528
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0039 0.0039
Echinococcus multilocularis regulator of G protein signaling 0.0318 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0294 0.1408 0.1379
Loa Loa (eye worm) uncoordinated protein 104 0.0042 0.0142 0.0109
Echinococcus granulosus GPCR family 2 0.005 0.0184 0.0184
Echinococcus multilocularis Oxysterol binding protein 11 0.0042 0.0142 0.0142
Echinococcus multilocularis pdz domain containing protein 0.0042 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni cell polarity protein 0.0062 0.0244 0.0211
Trypanosoma brucei protein kinase, putative 0.0052 0.0192 0.2698
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0178 0.0144
Echinococcus granulosus calcium dependent secretion activator 1 0.0042 0.0142 0.0142
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0121 0.0583
Entamoeba histolytica protein kinase, putative 0.0137 0.0621 0.393
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0072 0.0293 0.0397
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0039 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0039 0.0039
Echinococcus multilocularis gamma secretase subunit aph 1 0.0206 0.0966 0.0966
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0042 0.0142 0.6827
Trypanosoma cruzi Protein kinase B 0.0052 0.0192 0.5246
Schistosoma mansoni inositol monophosphatase 0.0037 0.0121 0.0087
Schistosoma mansoni hypothetical protein 0.0036 0.0116 0.0083
Echinococcus multilocularis beta adrenergic receptor kinase 0.2008 1 1
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0178 0.0178
Schistosoma mansoni unc-13 (munc13) 0.0062 0.0243 0.021
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0042 0.0142 0.6827
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0034 0.5
Toxoplasma gondii phosphatidylinositol transfer protein 0.0042 0.0142 0.2857
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Echinococcus multilocularis actin binding protein anillin 0.0042 0.0142 0.0142
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.0117 0.0117
Onchocerca volvulus 0.0042 0.0142 0.0754
Onchocerca volvulus 0.0072 0.0294 0.1864
Trypanosoma cruzi PB1 domain containing protein, putative 0.0062 0.0244 0.6947
Echinococcus multilocularis Pleckstrin y 0.0042 0.0142 0.0142
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0072 0.0293 0.0293
Entamoeba histolytica hypothetical protein 0.0052 0.0192 0.106
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0042 0.0142 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0116 0.0116
Brugia malayi hypothetical protein 0.0318 0.1528 0.2124
Loa Loa (eye worm) hypothetical protein 0.0108 0.0475 0.0442
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0051 0.0464
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0072 0.0293 0.0293
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0178 0.0178
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0052 0.0192 0.2698
Echinococcus multilocularis geminin 0.0158 0.0727 0.0727
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0318 0.1528 0.15
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0722 0.0691
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1123 0.5566 0.777
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0096 0.0412 0.0412
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0034 0.0034
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Echinococcus multilocularis calcium dependent secretion activator 1 0.0042 0.0142 0.0142
Echinococcus granulosus oxysterol binding protein 3 0.0042 0.0142 0.0142
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0178 0.0178
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0086 0.0362 0.2197
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0157 0.0722 0.0691
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0242 0.0209
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0039 0.0041
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.0259 0.0259
Schistosoma mansoni glutaminase 0.0298 0.1428 0.1399
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0178 0.0144
Brugia malayi Plekhf2 protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0039 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0051 0.1109
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0412 0.2534
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0039 0.0041
Onchocerca volvulus Protein TFG homolog 0.0062 0.0244 0.1497
Leishmania major protein kinase, putative 0.0052 0.0192 0.7552
Brugia malayi Cadps2 protein 0.0042 0.0142 0.0185
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Trichomonas vaginalis centaurin gamma, putative 0.0042 0.0142 0.0724
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0042 0.0142 0.6827
Echinococcus granulosus Regulator of G protein signaling 20 0.0318 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0184 0.0151
Schistosoma mansoni axis inhibition protein axin 0.0318 0.1528 0.15
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0178 0.0235
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0042 0.0142 0.0109
Echinococcus granulosus serine:threonine protein kinase N2 0.0096 0.0412 0.0412
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0039 0.0041
Schistosoma mansoni transient receptor potential channel 0.0098 0.0426 0.0394
Schistosoma mansoni rac gtpase activating protein 0.0062 0.0243 0.021
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Echinococcus multilocularis beta 1 syntrophin 0.0042 0.0142 0.0142
Brugia malayi Transient-receptor-potential like protein 0.0037 0.0117 0.015
Echinococcus granulosus Pleckstrin y 0.0042 0.0142 0.0142
Trichomonas vaginalis alpha chimerin, putative 0.0042 0.0142 0.0724
Mycobacterium ulcerans glutaminase 0.0298 0.1428 1
Echinococcus granulosus DCC interacting protein 13 beta 0.0042 0.0142 0.0142
Echinococcus granulosus Rho GTPase activating protein 24 0.0042 0.0142 0.0142
Schistosoma mansoni axis inhibition protein axin 0.0318 0.1528 0.15
Schistosoma mansoni centaurin alpha 0.0042 0.0142 0.0109
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0051 0.0299
Entamoeba histolytica protein kinase, putative 0.0096 0.0412 0.2534
Schistosoma mansoni transient receptor potential channel 0.0065 0.0259 0.0226
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Brugia malayi Uncoordinated protein 104 0.0042 0.0142 0.0185
Loa Loa (eye worm) glutaminase 0.0298 0.1428 0.1399
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0318 0.1528 0.15
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni goodpasture antigen-binding protein 0.0042 0.0142 0.0109
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0042 0.0142 0.0109
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis transient receptor potential gamma protein 0.0098 0.0426 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0293 0.0261
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0042 0.0142 0.3581
Echinococcus multilocularis dynamin 1 0.0042 0.0142 0.0142
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0072 0.0294 0.0261
Echinococcus granulosus c-Jun N-terminal kinases 0.0255 0.1212 0.1212
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0034 0.0034
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0318 0.1528 1
Schistosoma mansoni goodpasture antigen-binding protein 0.0042 0.0142 0.0109
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0042 0.0142 0.0142
Schistosoma mansoni z-protein (S1r protein) 0.0318 0.1528 0.15
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0039 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0039 0.0041
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Echinococcus multilocularis Regulator of G protein signaling 20 0.0318 0.1528 0.1528
Schistosoma mansoni coup transcription factor 0.0021 0.0039 0.0005
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Brugia malayi Dynamin 0.0042 0.0142 0.0185
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0242 0.0242
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0243 0.021
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0052 0.0192 0.5246
Echinococcus multilocularis unc 13 (munc13) 0.0062 0.0243 0.0243
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0052 0.0192 1
Schistosoma mansoni gamma-secretase subunit aph-1 0.0206 0.0966 0.0936
Loa Loa (eye worm) PXA domain-containing protein 0.0318 0.1528 0.15
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0062 0.0243 0.0243
Echinococcus multilocularis GRB2 associated binding protein 3 0.0042 0.0142 0.0142
Brugia malayi CXXC zinc finger family protein 0.0029 0.0079 0.0097
Brugia malayi RhoGEF domain containing protein 0.0062 0.0243 0.0327
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Loa Loa (eye worm) hypothetical protein 0.0096 0.0412 0.038
Entamoeba histolytica hypothetical protein 0.0318 0.1528 1
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0052 0.0192 0.7552
Onchocerca volvulus Putative zinc finger protein 0.0042 0.0142 0.0754
Brugia malayi p70 ribosomal S6 kinase beta 0.0096 0.0412 0.0563
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0242 0.1491
Brugia malayi Protein kinase domain containing protein 0.0072 0.0294 0.0398
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0157 0.0722 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0039 0.0039
Trichomonas vaginalis hypothetical protein 0.0042 0.0142 0.0724
Echinococcus multilocularis regulator of G protein signaling 7 0.0318 0.1528 0.1528
Brugia malayi Oxysterol-binding protein 0.0042 0.0142 0.0185
Trichomonas vaginalis centaurin/arf, putative 0.0042 0.0142 0.0724
Brugia malayi Regulator of G protein signaling domain containing protein 0.0318 0.1528 0.2124
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0039 0.0041
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0192 0.5246
Echinococcus granulosus Pleckstrin y 0.0042 0.0142 0.0142
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0096 0.0412 0.038
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0039 0.0041
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0192 0.0159
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0042 0.0142 0.0142
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1123 0.5566 0.5551
Onchocerca volvulus 0.0042 0.0142 0.0754
Echinococcus granulosus cytohesin 1 0.0042 0.0142 0.0142
Schistosoma mansoni dynamin 0.0042 0.0142 0.0109
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0184 0.0184
Entamoeba histolytica hypothetical protein, conserved 0.0062 0.0244 0.1404
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0052 0.0192 0.2698
Brugia malayi latrophilin 2 splice variant baaae 0.0108 0.0475 0.0651
Echinococcus granulosus gamma secretase subunit aph 1 0.0206 0.0966 0.0966
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0142 0.6827
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0121 1
Echinococcus granulosus NDR protein kinase 0.0096 0.0412 0.0412
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0042 0.0142 0.0185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Schistosoma mansoni syntrophin 0.0042 0.0142 0.0109
Echinococcus granulosus regulator of G protein signaling 3 0.0318 0.1528 0.1528
Schistosoma mansoni transient receptor potential channel 4 0.0098 0.0426 0.0394
Echinococcus granulosus unc 13 munc13 0.0062 0.0243 0.0243
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Plasmodium vivax PH domain containing protein 0.0042 0.0142 0.6827
Echinococcus multilocularis dnaJ subfamily B 0.0414 0.201 0.201
Echinococcus multilocularis Diacylglycerol kinase theta 0.0062 0.0243 0.0243
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Echinococcus multilocularis oxysterol binding protein 9 0.0042 0.0142 0.0142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0158 0.0725 0.0694
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus axis inhibition protein axin 0.0318 0.1528 0.1528
Trichomonas vaginalis centaurin/arf, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0042 0.0142 0.0142
Loa Loa (eye worm) RasGEF domain-containing protein 0.0062 0.0243 0.021
Brugia malayi follicle stimulating hormone receptor 0.0247 0.1171 0.1624
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0101 0.3244
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0039 0.0041
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0096 0.0412 0.0412
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Schistosoma mansoni oxysterol-binding protein 1 0.0042 0.0142 0.0109
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0121 0.23
Echinococcus multilocularis axis inhibition protein axin 0.0318 0.1528 0.1528
Echinococcus multilocularis expressed protein 0.0318 0.1528 0.1528
Echinococcus granulosus protein kinase c iota type 0.1 0.4949 0.4949
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.0259 0.0259
Echinococcus granulosus N chimaerin 0.0062 0.0243 0.0243
Echinococcus multilocularis transient receptor potential ion channel A 0.0095 0.041 0.041
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0109
Schistosoma mansoni vav2 0.0103 0.0452 0.0419
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) hypothetical protein 0.0033 0.01 0.0067
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0318 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Echinococcus multilocularis Rho GTPase activating protein 24 0.0042 0.0142 0.0142
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0039 0.0039
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0142 0.0724
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0586 0.0554
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0042 0.0142 0.0754
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Leishmania major folate/biopterin transporter, putative 0.0052 0.0192 0.7552
Echinococcus granulosus raf serine:threonine protein kinase 0.0062 0.0243 0.0243
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0039 0.0039
Echinococcus multilocularis regulator of G protein signaling 3 0.0318 0.1528 0.1528
Entamoeba histolytica diacylglycerol kinase, putative 0.0062 0.0243 0.1401
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0121 0.0121
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0062 0.0243 0.021
Trichomonas vaginalis glutaminase, putative 0.0298 0.1428 0.9327
Brugia malayi hypothetical protein 0.0036 0.0116 0.0149
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1123 0.5566 0.5566
Brugia malayi Stress-activated protein kinase jnk-1 0.0255 0.1212 0.1682
Onchocerca volvulus 0.0042 0.0142 0.0754
Brugia malayi regulator of G-protein signaling egl-10 0.0318 0.1528 0.2124
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.0259 0.0259
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0042 0.0142 0.0142
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0158 0.0725 0.1001
Loa Loa (eye worm) glutaminase 2 0.0298 0.1428 0.1399
Echinococcus multilocularis raf serine:threonine protein kinase 0.0062 0.0243 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.1212 0.1183
Echinococcus granulosus regulator of G protein signaling 7 0.0318 0.1528 0.1528
Entamoeba histolytica protein kinase, putative 0.0096 0.0412 0.2534
Echinococcus granulosus axis inhibition protein axin 0.0318 0.1528 0.1528
Loa Loa (eye worm) rho-GTPase-activating 0.0042 0.0142 0.0109
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0042 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.1442 0.7161 0.7151
Onchocerca volvulus 0.0042 0.0142 0.0754
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0242 0.1491
Brugia malayi Ras association domain family 1 isoform A 0.0062 0.0243 0.0327
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0042 0.0142 0.0754
Echinococcus multilocularis protein kinase c iota type 0.1 0.4949 0.4949
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0178 0.0144
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0318 0.1528 0.1528
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Schistosoma mansoni myotubularin-related protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0096 0.0412 0.038
Echinococcus granulosus geminin 0.0158 0.0727 0.0727
Trichomonas vaginalis kinesin light chain, putative 0.0042 0.0142 0.0724
Echinococcus granulosus cpg binding protein 0.0031 0.0087 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.1171 0.1141
Echinococcus granulosus regulator of G protein signaling 7 0.0318 0.1528 0.1528
Entamoeba histolytica hypothetical protein 0.0052 0.0192 0.106
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2008 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.2883
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Leishmania major hypothetical protein, conserved 0.0062 0.0244 1
Echinococcus granulosus Pleckstrin y 0.0042 0.0142 0.0142
Echinococcus granulosus myotubularin protein 13 0.0103 0.0452 0.0452
Schistosoma mansoni diacylglycerol kinase theta 0.0062 0.0243 0.021
Brugia malayi Protein kinase domain containing protein 0.0072 0.0293 0.0397
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0052 0.0192 0.5246
Echinococcus multilocularis Ras associated and pleckstrin y 0.0042 0.0142 0.0142
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0121 0.0583
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0079 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0096 0.0412 0.0412
Echinococcus granulosus beta 1 syntrophin 0.0042 0.0142 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0039 0.0005
Echinococcus granulosus pdz domain containing protein 0.0042 0.0142 0.0142
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0052 0.0192 0.2698
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0042 0.0142 0.0142
Brugia malayi hypothetical protein 0.0042 0.0142 0.0185
Schistosoma mansoni zinc finger protein 0.0042 0.0142 0.0109
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0039 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0722 0.0691
Leishmania major hypothetical protein, conserved 0.0024 0.0051 0.0837
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Onchocerca volvulus 0.0029 0.0079 0.0296
Schistosoma mansoni serine/threonine kinase 0.0096 0.0412 0.038
Echinococcus granulosus transient receptor potential ion channel A 0.0095 0.041 0.041
Echinococcus multilocularis oxysterol binding protein 1 0.0042 0.0142 0.0142
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0255 0.1212 0.1183
Onchocerca volvulus 0.0062 0.0244 0.1497
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0185
Onchocerca volvulus 0.0042 0.0142 0.0754
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0042 0.0142 0.6827
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0042 0.0142 0.0142
Plasmodium falciparum oxysterol-binding protein, putative 0.0042 0.0142 0.6827
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0042 0.0142 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Brugia malayi probable spectrin beta chain 0.0042 0.0142 0.0185
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0206 0.0966 0.0936
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.0117 0.0117
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0052 0.0192 0.5246
Trichomonas vaginalis centaurin beta, putative 0.0042 0.0142 0.0724
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0242 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0142 0.6827
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0042 0.0142 0.0724
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus granulosus GRB2 associated binding protein 3 0.0042 0.0142 0.0142
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0062 0.0243 0.021
Brugia malayi Dynamin 0.0042 0.0142 0.0185
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0039 0.0005
Echinococcus multilocularis GPCR, family 2 0.005 0.0184 0.0184
Brugia malayi Cytohesin 3 0.0042 0.0142 0.0185
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0052 0.0192 0.106
Echinococcus multilocularis pleckstrin y domain containing family A 0.0042 0.0142 0.0142
Entamoeba histolytica ARF GTPase activating protein, putative 0.0042 0.0142 0.0724
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0039 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0039 0.0005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0039 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0062 0.0243 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0039 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0039 0.0041
Brugia malayi Variant SH3 domain containing protein 0.0042 0.0142 0.0185
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0142 0.6827
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0052 0.0192 0.106
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Schistosoma mansoni unc-13 (munc13) 0.0062 0.0243 0.021
Trypanosoma cruzi Aph-1 protein, putative 0.008 0.0336 1
Schistosoma mansoni protein kinase C mu 0.0072 0.0293 0.0261
Echinococcus multilocularis Pleckstrin y 0.0042 0.0142 0.0142
Loa Loa (eye worm) inositol-1 0.0037 0.0121 0.0087
Entamoeba histolytica PH domain containing protein 0.0042 0.0142 0.0724
Echinococcus granulosus Oxysterol binding protein 11 0.0042 0.0142 0.0142
Echinococcus multilocularis serine:threonine protein kinase N2 0.0096 0.0412 0.0412
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0977 0.4831 0.4813
Trypanosoma brucei PH domain containing protein, putative 0.0042 0.0142 0.1842
Schistosoma mansoni cpg binding protein 0.0029 0.0079 0.0046
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Trypanosoma cruzi NIMA-related kinase, putative 0.0052 0.0192 0.5246
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0042 0.0142 0.0109
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0121 0.0583
Loa Loa (eye worm) AGC/NDR protein kinase 0.0096 0.0412 0.038
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0052 0.0192 0.5246
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0039 0.0039
Brugia malayi TBC domain containing protein 0.0042 0.0142 0.0185
Leishmania major hypothetical protein, conserved 0.0042 0.0142 0.5156
Schistosoma mansoni regulator of G protein signaling 0.0318 0.1528 0.15
Schistosoma mansoni dynamin 0.0042 0.0142 0.0109
Toxoplasma gondii hypothetical protein 0.0042 0.0142 0.2857
Echinococcus granulosus oxysterol binding protein 1 0.0042 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0184 0.0184
Entamoeba histolytica diacylglycerol kinase, putative 0.0062 0.0243 0.1401
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0042 0.0142 0.3581
Brugia malayi Protein kinase c protein 2 0.0072 0.0293 0.0397
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0051 0.0018
Onchocerca volvulus 0.0062 0.0243 0.1494
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0192 0.106
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0039 0.0039
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0034 0.0034
Echinococcus multilocularis partitioning defective protein 6 0.0062 0.0244 0.0244
Brugia malayi Variant SH3 domain containing protein 0.0042 0.0142 0.0185
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0062 0.0243 0.021
Trypanosoma cruzi PB1 domain containing protein, putative 0.0062 0.0244 0.6947
Brugia malayi PXA domain containing protein 0.0318 0.1528 0.2124
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0242 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0722 0.0691
Brugia malayi Inositol-1 0.0037 0.0121 0.0156
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Brugia malayi Protein kinase domain containing protein 0.0137 0.0621 0.0855
Loa Loa (eye worm) cytohesin 3 0.0042 0.0142 0.0109
Brugia malayi nuclear receptor NHR-88 0.0021 0.0039 0.0041
Brugia malayi Pleckstrin Homology Domain 0.0103 0.0452 0.0619
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0039 0.0041
Plasmodium falciparum PH domain-containing protein, putative 0.0042 0.0142 0.6827
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0052 0.0192 0.7552
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0142 0.3581
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0042 0.0142 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0293 0.0261
Schistosoma mansoni hypothetical protein 0.0062 0.0243 0.021
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0034 0.5
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0042 0.0142 0.0142
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Onchocerca volvulus 0.0042 0.0142 0.0754
Toxoplasma gondii AGC kinase 0.0096 0.0412 1
Echinococcus granulosus protein kinase C gamma type 0.0096 0.0412 0.0412
Onchocerca volvulus outspread protein homolog 0.0042 0.0142 0.0754
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0096 0.0412 0.0412
Echinococcus multilocularis serine threonine protein kinase 0.0096 0.0412 0.0412
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus multilocularis axis inhibition protein axin 0.0318 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0192 0.0159
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.0151
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0052 0.0192 0.5246
Loa Loa (eye worm) hypothetical protein 0.0103 0.0452 0.0419
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0178 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0039 0.0005
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0192 0.5246
Brugia malayi PXA domain containing protein 0.0318 0.1528 0.2124
Echinococcus granulosus serine/threonine protein kinase 0.0052 0.0192 0.0192
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0318 0.1528 0.15
Trichomonas vaginalis protein transport protein sec7, putative 0.0042 0.0142 0.0724
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0121 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0039 0.0041
Echinococcus multilocularis protein kinase c epsilon type 0.0157 0.0722 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Onchocerca volvulus 0.0294 0.1408 1
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1123 0.5566 0.5566
Echinococcus granulosus protein kinase c eta type 0.0062 0.0243 0.0243
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Schistosoma mansoni protein kinase C mu 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0098 0.0426 0.0394
Echinococcus multilocularis cpg binding protein 0.0031 0.0087 0.0087
Echinococcus multilocularis Pleckstrin y 0.0042 0.0142 0.0142
Trichomonas vaginalis centaurin alpha, putative 0.0042 0.0142 0.0724
Brugia malayi nuclear hormone receptor 0.0021 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0103 0.0452 0.0419
Onchocerca volvulus 0.0062 0.0243 0.1494
Plasmodium falciparum calcium-dependent protein kinase 7 0.0052 0.0192 1
Schistosoma mansoni growth factor receptor-bound protein 0.0042 0.0142 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.2008 1 1
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0242 0.9906
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0042 0.0142 0.0142
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0042 0.0142 0.0142
Echinococcus granulosus Diacylglycerol kinase theta 0.0062 0.0243 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.2008 1 1
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0412 0.2534
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0051 0.0582
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0039 0.0005
Echinococcus multilocularis protein TFG 0.0062 0.0244 0.0244
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Brugia malayi MAX-1A 0.0042 0.0142 0.0185
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0052 0.0192 0.4185
Entamoeba histolytica hypothetical protein 0.0318 0.1528 1
Echinococcus multilocularis protein kinase c eta type 0.0062 0.0243 0.0243
Brugia malayi protein kinase C3,putative 0.0915 0.452 0.6307
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0116 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0039 0.0039
Echinococcus multilocularis myotubularin protein 13 0.0103 0.0452 0.0452
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0051 0.1109
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Toxoplasma gondii AtPH1 family protein 0.0042 0.0142 0.2857
Echinococcus granulosus pleckstrin y domain containing family A 0.0042 0.0142 0.0142
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0039 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0039 0.0005
Brugia malayi A-kinase anchor protein 10, precursor 0.0318 0.1528 0.2124
Trypanosoma brucei Aph-1 protein, putative 0.008 0.0336 0.5143
Loa Loa (eye worm) PAR-6 protein 0.0062 0.0244 0.0211
Brugia malayi steroid hormone receptor 0.0021 0.0039 0.0041
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0039 0.0039
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.1483
Echinococcus multilocularis regulator of G protein signaling 7 0.0318 0.1528 0.1528
Echinococcus granulosus regulator of G protein signaling 3 0.0318 0.1528 0.1528
Brugia malayi gamma-secretase subunit aph-1 0.0206 0.0966 0.1338
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Schistosoma mansoni hypothetical protein 0.0158 0.0727 0.0695
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0042 0.0142 0.0724
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Loa Loa (eye worm) RGS-3 protein 0.0318 0.1528 0.15
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0042 0.0142 0.0109
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Entamoeba histolytica hypothetical protein 0.0062 0.0243 0.1401
Leishmania major protein kinase, putative 0.0052 0.0192 0.7552
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0062 0.0243 0.021
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0062 0.0243 0.021
Loa Loa (eye worm) PH domain-containing protein 0.0042 0.0142 0.0109
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0051 0.0582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0244 0.0211
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0039 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0621 0.393
Brugia malayi MH2 domain containing protein 0.013 0.0586 0.0806
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.021
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0184 0.0244
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Brugia malayi Calcitonin receptor-like protein seb-1 0.0158 0.0725 0.1001
Toxoplasma gondii hypothetical protein 0.0042 0.0142 0.2857
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0042 0.0142 0.0142
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0042 0.0142 0.0109
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1123 0.5566 0.5551
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.1528 1
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0255 0.1212 0.1212
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0096 0.0412 0.0412
Loa Loa (eye worm) raf kinase 0.0062 0.0243 0.021
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Brugia malayi RhoGAP domain containing protein 0.0062 0.0243 0.0327
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0051 0.1109
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0062 0.0243 0.0243
Loa Loa (eye worm) AGC/PKN protein kinase 0.0096 0.0412 0.038
Echinococcus granulosus protein TFG 0.0062 0.0244 0.0244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0039 0.0005
Brugia malayi Hr1 repeat family protein 0.0096 0.0412 0.0563
Trypanosoma cruzi Aph-1 protein, putative 0.008 0.0336 1
Trypanosoma cruzi NIMA-related kinase, putative 0.0052 0.0192 0.5246
Echinococcus granulosus oxysterol binding protein 9 0.0042 0.0142 0.0142
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0052 0.0192 0.5246
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0062 0.0243 0.0243
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0142 0.0724
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0096 0.0412 0.038
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus multilocularis rac serine:threonine kinase 0.0052 0.0192 0.0192
Entamoeba histolytica hypothetical protein 0.0036 0.0116 0.055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0039 0.0041
Brugia malayi Oxysterol binding protein 0.0042 0.0142 0.0185
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1442 0.7161 1
Schistosoma mansoni oxysterol-binding protein 1 0.0042 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0142 0.0109
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1442 0.7161 0.7151
Brugia malayi Partitioning defective-6 homolog alpha 0.0062 0.0244 0.0327
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0586 0.0554
Onchocerca volvulus 0.0103 0.0452 0.3017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0178 0.0144
Brugia malayi regulator of G-protein signaling rgs-7 0.0318 0.1528 0.2124
Schistosoma mansoni cpg binding protein 0.0031 0.0087 0.0054
Entamoeba histolytica PH domain containing protein 0.0042 0.0142 0.0724
Entamoeba histolytica p21-activated kinase 0.0052 0.0192 0.106
Echinococcus granulosus protein kinase c epsilon type 0.0157 0.0722 0.0722
Loa Loa (eye worm) hypothetical protein 0.0037 0.0117 0.0083
Toxoplasma gondii protein kinase domain-containing protein 0.0052 0.0192 0.4185
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0052 0.0192 0.5246
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0242 0.1491
Echinococcus multilocularis G protein coupled receptor kinase 1 0.169 0.8405 0.8405
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0042 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0042 0.0142 0.0724
Entamoeba histolytica protein kinase, putative 0.0052 0.0192 0.106
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.2883
Entamoeba histolytica hypothetical protein 0.0042 0.0142 0.0724
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0121 0.415
Leishmania major hypothetical protein, conserved 0.0042 0.0142 0.5156
Leishmania major serine/threonine-protein kinase a, putative 0.0052 0.0192 0.7552
Loa Loa (eye worm) syntrophin-1 0.0042 0.0142 0.0109
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0121 0.0583
Echinococcus granulosus transient receptor potential gamma protein 0.0098 0.0426 0.0426
Entamoeba histolytica hypothetical protein 0.0318 0.1528 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0039 0.0039
Echinococcus multilocularis oxysterol binding protein 3 0.0042 0.0142 0.0142
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0142 0.0724
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0039 0.0005
Trypanosoma cruzi hypothetical protein 0.0042 0.0142 0.3581
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Brugia malayi Latrophilin receptor protein 2 0.005 0.0184 0.0244
Brugia malayi Regulator of G protein signaling domain containing protein 0.0318 0.1528 0.2124
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0142 0.0724
Echinococcus granulosus Rac GTPase activating protein 1 0.0062 0.0243 0.0243
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0039 0.0041
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0184 0.0184
Trypanosoma brucei PB1 domain containing protein, putative 0.0062 0.0244 0.3573
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0243 0.021
Brugia malayi Syntrophin-1 0.0042 0.0142 0.0185
Echinococcus multilocularis regulator of G protein signaling 3 0.0318 0.1528 0.1528
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Brugia malayi Variant SH3 domain containing protein 0.0062 0.0243 0.0327
Loa Loa (eye worm) Plekhf2 protein 0.0042 0.0142 0.0109
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.021 0.4644
Toxoplasma gondii Oxysterol-binding protein 0.0042 0.0142 0.2857
Schistosoma mansoni hypothetical protein 0.0158 0.0727 0.0695
Schistosoma mansoni protein kinase C 0.0062 0.0243 0.021
Echinococcus multilocularis N chimaerin 0.0062 0.0243 0.0243
Echinococcus multilocularis serine:threonine protein kinase 38 0.0096 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0158 0.0725 0.0694
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0151
Schistosoma mansoni hypothetical protein 0.0414 0.201 0.1983
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0042 0.0142 0.0142
Loa Loa (eye worm) oxysterol binding protein 0.0042 0.0142 0.0109
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0242 0.0242
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0096 0.0412 0.0412
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Schistosoma mansoni diacylglycerol kinase theta 0.0062 0.0243 0.021
Schistosoma mansoni hypothetical protein 0.0042 0.0142 0.0109
Brugia malayi diacylglycerol kinase 0.0062 0.0243 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0192 0.106
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0042 0.0142 0.0142
Schistosoma mansoni rho gtpase activating protein 0.0042 0.0142 0.0109
Toxoplasma gondii diacylglycerol kinase, putative 0.0062 0.0243 0.5531
Loa Loa (eye worm) hypothetical protein 0.0318 0.1528 0.15
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0039 0.0041
Brugia malayi PH domain containing protein 0.0042 0.0142 0.0185
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0142 0.0724
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0412 0.038
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0242 0.549
Echinococcus multilocularis Rac GTPase activating protein 1 0.0062 0.0243 0.0243
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0039 0.0039
Onchocerca volvulus Protein melted homolog 0.0042 0.0142 0.0754
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0005
Brugia malayi protein kinase C II. 0.0157 0.0722 0.0997

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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