Detailed information for compound 1845999

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1064.14 | Formula: C52H69N7O17
  • H donors: 14 H acceptors: 16 LogP: 0.47 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCOc1ccc(cc1)Cc1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@H](CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC1=O)[C@H](O)C)C[C@@H](C2)O)[C@@H]([C@H](c1ccc(cc1)O)O)O)[C@H](O)C)C
  • InChi: 1S/C52H69N7O17/c1-5-6-19-76-34-17-9-29(10-18-34)20-28-7-11-31(12-8-28)45(68)53-35-22-37(64)48(71)57-50(73)41-42(65)25(2)23-59(41)52(75)39(27(4)61)55-49(72)40(44(67)43(66)30-13-15-32(62)16-14-30)56-47(70)36-21-33(63)24-58(36)51(74)38(26(3)60)54-46(35)69/h7-18,25-27,33,35-44,48,60-67,71H,5-6,19-24H2,1-4H3,(H,53,68)(H,54,69)(H,55,72)(H,56,70)(H,57,73)/t25-,26+,27+,33+,35-,36-,37+,38-,39-,40-,41-,42-,43-,44-,48+/m0/s1
  • InChiKey: CVERNVBRIMOIKB-OISCXZEMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0016 0.0036
Plasmodium falciparum casein kinase 2, alpha subunit 0.0138 0.0233 0.7124
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.002 0.001 0.0068
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0107 0.0175 0.1242
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0107 0.0175 0.5313
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0188 0.0326 0.0326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0459 0.0837 0.6042
Schistosoma mansoni plexin 0.0335 0.0604 0.2959
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0325 0.0584 0.4223
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0016 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0021 0.0013 0.0064
Brugia malayi bone morphogenetic protein type 1 receptor 0.0016 0.0004 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0046 0.0223
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0046 0.0837
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.0338 0.1654
Loa Loa (eye worm) phosphatidylinositol 3 0.052 0.0951 0.5256
Giardia lamblia Hypothetical protein 0.0107 0.0175 0.1809
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0142 0.0698
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0046 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.0175 0.1265
Echinococcus granulosus expressed conserved protein 0.0082 0.0128 0.0128
Entamoeba histolytica ankyrin repeat protein 0.0016 0.0004 0.000000051443
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.014 0.0236 0.1306
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.031 0.0557 0.5839
Echinococcus multilocularis Zinc finger, PHD finger 0.0188 0.0326 0.0326
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.002 0.0049
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Mycobacterium ulcerans beta-lactamase 0.0039 0.0046 0.2115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0501 0.0916 0.6613
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.001 0.002
Brugia malayi Cytochrome P450 family protein 0.002 0.001 0.0069
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0459 0.0837 0.88
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1098 0.204 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0156 0.1105
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Brugia malayi Serotonin receptor 0.0472 0.086 0.6221
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.018 0.1276
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Giardia lamblia Kinase, PLK 0.0194 0.0338 0.3525
Echinococcus granulosus geminin 0.017 0.0293 0.0293
Onchocerca volvulus 0.014 0.0236 0.3914
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0016 0.0004 0.0026
Echinococcus granulosus survival motor neuron protein 1 0.0476 0.0869 0.0869
Schistosoma mansoni tyrosine kinase 0.0022 0.0013 0.0065
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0024 0.0148
Plasmodium vivax hypothetical protein 0.0107 0.0175 0.5313
Echinococcus multilocularis expressed conserved protein 0.0082 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.0097 0.0156 0.0762
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0016 0.0004 0.0004
Entamoeba histolytica phosphofructokinase, putative 0.011 0.018 0.1276
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0046 0.0837
Brugia malayi hypoxia-induced factor 1 0.0152 0.0259 0.1875
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0175 0.3858
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0016 0.0016
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0034 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0046 0.0304
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0016 0.0086
Loa Loa (eye worm) hypothetical protein 0.0195 0.034 0.1879
Brugia malayi hypothetical protein 0.0019 0.0009 0.0067
Brugia malayi follicle stimulating hormone receptor 0.0239 0.0423 0.3055
Echinococcus granulosus integrin linked protein kinase 0.0016 0.0004 0.0004
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.052 0.0951 0.2593
Echinococcus granulosus tumor protein p63 0.0342 0.0616 0.0616
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0017
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0004
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0009 0.0009
Echinococcus granulosus lamin dm0 0.0027 0.0024 0.0024
Echinococcus granulosus tyrosine protein kinase shark 0.0022 0.0013 0.0013
Loa Loa (eye worm) serine/threonine protein kinase 0.0016 0.0004 0.002
Leishmania major protein kinase, putative 0.0016 0.0004 0.0001
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0016 0.0004 0.0004
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0142 0.0698
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0269 0.048 0.048
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0013 0.0013
Echinococcus granulosus importin subunit beta 1 0.0031 0.0031 0.0031
Leishmania major phosphatidylinositol 3-kinase, putative 0.0188 0.0326 0.0884
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.0172
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0107 0.0175 0.0175
Echinococcus multilocularis activated cdc42 kinase 1 0.0016 0.0004 0.0004
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0004 0.0026
Brugia malayi Tyrosine-protein kinase abl-1 0.0021 0.0013 0.0095
Brugia malayi Csnk2b protein 0.0037 0.0042 0.0307
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0029 0.0029
Brugia malayi SH2 domain containing protein 0.0021 0.0013 0.0095
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0046 0.0837
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0013 0.0013
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Entamoeba histolytica hypothetical protein 0.0107 0.0175 0.1242
Loa Loa (eye worm) hypothetical protein 0.0102 0.0164 0.0908
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.082 0.1516 0.1516
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0021 0.0013 0.0013
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.018 0.0511
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0017
Echinococcus multilocularis tyrosine protein kinase Srms 0.0021 0.0013 0.0013
Onchocerca volvulus 0.0016 0.0004 0.0058
Brugia malayi intracellular kinase 0.0052 0.007 0.0504
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0012 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.055 0.3957
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0041
Entamoeba histolytica hypothetical protein 0.0061 0.0088 0.0613
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0016 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0041 0.0041
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0749 0.1383 1
Brugia malayi Protein kinase domain containing protein 0.0018 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.0297 0.0532 0.2943
Brugia malayi SH2 domain containing protein 0.0344 0.062 0.4481
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0032 0.0034 0.0165
Brugia malayi RNA, U transporter 1 0.0088 0.0139 0.1002
Echinococcus multilocularis tyrosine protein kinase HCK 0.0016 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0133
Giardia lamblia GTOR 0.052 0.0951 1
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0046 0.0837
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0000078591 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Trypanosoma brucei protein kinase, putative 0.0052 0.007 0.0698
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0016 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0041
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0013 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Loa Loa (eye worm) hypothetical protein 0.0476 0.0869 0.4805
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0009 0.0051
Schistosoma mansoni protein tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.014 0.0236 0.1306
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0000078662 0.0000000070971
Toxoplasma gondii hypothetical protein 0.0054 0.0075 0.0786
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0041
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0046 0.0329
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.052 0.0951 0.2593
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0181
Entamoeba histolytica casein kinase, putative 0.0138 0.0233 0.1666
Giardia lamblia Kinase, CMGC CK2 0.0138 0.0233 0.2426
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0016 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.019 0.033 0.1619
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0009 0.0009
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0544 0.0997 0.0997
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.001 0.0053
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Echinococcus multilocularis tyrosine kinase 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0325 0.0584 0.4223
Brugia malayi hypothetical protein 0.0016 0.0004 0.0026
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0042 0.0282
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0042 0.0235
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0046 0.1301
Brugia malayi hypothetical protein 0.0019 0.0009 0.0067
Echinococcus granulosus exocyst complex component 2 0.0061 0.0088 0.0088
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.018 0.0993
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.001 0.0053
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0016 0.0004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0233 0.1666
Schistosoma mansoni hypothetical protein 0.0061 0.0088 0.0432
Trichomonas vaginalis esterase, putative 0.0039 0.0046 0.0304
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0024 0.0131
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.018 0.0993
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0188 0.0326 0.0326
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.5326 1 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0016 0.0004 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.018 0.1276
Echinococcus granulosus bloom syndrome protein 0.0021 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Brugia malayi PAS domain containing protein 0.0049 0.0065 0.0472
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0642 0.1181 0.8534
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0013 0.0068
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0029 0.5
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Echinococcus granulosus cyclin dependent kinase 19 0.0135 0.0227 0.0227
Brugia malayi ephrin receptor 1 precursor 0.0016 0.0004 0.0026
Echinococcus granulosus semaphorin 1A 0.014 0.0236 0.0236
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0062 0.0089 0.09
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0269 0.048 0.3468
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0188 0.0326 0.2358
Echinococcus granulosus tyrosine protein kinase pr2 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0269 0.048 0.2651
Loa Loa (eye worm) hypothetical protein 0.014 0.0236 0.1306
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0016 0.0004 0.002
Echinococcus multilocularis FL cytokine receptor 0.0016 0.0004 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.007 0.0479
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0009 0.0009
Brugia malayi Casein kinase II, alpha chain 0.0138 0.0233 0.1687
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0051
Schistosoma mansoni protein kinase 0.0017 0.0004 0.0018
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0016 0.0004 0.002
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0052 0.007 0.0385
Echinococcus multilocularis exocyst complex component 2 0.0061 0.0088 0.0088
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0325 0.0584 0.3228
Loa Loa (eye worm) hypothetical protein 0.0544 0.0997 0.5509
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Schistosoma mansoni ephrin receptor 0.0016 0.0004 0.0017
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0009 0.0009
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1098 0.204 0.204
Mycobacterium ulcerans hypothetical protein 0.0039 0.0046 0.2115
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0016 0.0004 0.002
Plasmodium falciparum protein kinase, putative 0.002 0.001 0.02
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0016 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.055 0.3957
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Leishmania major ATP-dependent phosphofructokinase 0.011 0.018 0.0483
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0009 0.0067
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0016 0.0004 0.002
Brugia malayi hypothetical protein 0.0036 0.0041 0.0298
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0013 0.0013
Loa Loa (eye worm) TK/ROR protein kinase 0.0016 0.0004 0.002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.0175 0.1265
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0177 0.0305 0.0875
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Onchocerca volvulus Serine\/threonine kinase homolog 0.0194 0.0338 0.5592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6295
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Schistosoma mansoni kinase 0.01 0.0161 0.0788
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0145 0.0245 0.2546
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0027
Schistosoma mansoni protein kinase 0.002 0.001 0.0049
Onchocerca volvulus 0.0016 0.0004 0.0058
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0016 0.0016
Brugia malayi PXA domain containing protein 0.0021 0.0012 0.0086
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0016 0.0004 0.0026
Echinococcus multilocularis hypothetical protein 0.014 0.0236 0.0236
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0107 0.0175 0.0175
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0061 0.0088 0.0488
Echinococcus multilocularis cyclin dependent kinase 19 0.0135 0.0227 0.0227
Schistosoma mansoni 6-phosphofructokinase 0.011 0.018 0.088
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.0259 0.1433
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.0004 0.000000051443
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0016 0.0004 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0017
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0042 0.0114
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.018 1
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.019 0.033 0.033
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0052 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Schistosoma mansoni ran 0.0023 0.0016 0.0076
Echinococcus multilocularis tyrosine protein kinase Abl 0.0021 0.0013 0.0013
Schistosoma mansoni ephrin receptor 0.0016 0.0004 0.0017
Giardia lamblia Kinase, NEK 0.0017 0.0004 0.0002
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0016 0.0016
Trypanosoma cruzi polo-like protein kinase, putative 0.0194 0.0338 0.0968
Echinococcus multilocularis lamin dm0 0.0027 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0061 0.0088 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.019 0.033 0.2368
Onchocerca volvulus 0.0102 0.0164 0.2716
Echinococcus multilocularis protein KINase family member (kin 25) 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0252
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0042 0.1204
Onchocerca volvulus 0.0107 0.0175 0.2898
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0046 0.0443
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0088 0.0138 0.0137
Onchocerca volvulus 0.0039 0.0046 0.0753
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0051
Mycobacterium leprae conserved hypothetical protein 0.0107 0.0175 0.9726
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0045
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0031 0.029
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0016 0.0004 0.002
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.031 0.0557 0.4009
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0188 0.0326 0.357
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0016 0.0004 0.0058
Onchocerca volvulus 0.0052 0.007 0.1154
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0024 0.0171
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0016 0.0004 0.0026
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.051 0.0933 0.4573
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0188 0.0326 0.2338
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0009 0.0009
Echinococcus multilocularis tumor protein p63 0.0342 0.0616 0.0616
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Entamoeba histolytica phosphofructokinase, putative 0.011 0.018 0.1276
Loa Loa (eye worm) hypothetical protein 0.003 0.0029 0.0161
Brugia malayi Tyrosine-protein kinase PR2 0.0016 0.0004 0.0026
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0331 0.0595 0.3291
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0016 0.0004 0.0004
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0009 0.0067
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.0119 0.0837
Echinococcus multilocularis tyrosine protein kinase shark 0.0022 0.0013 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Echinococcus granulosus activated cdc42 kinase 1 0.0016 0.0004 0.0004
Trypanosoma brucei Casein kinase II 0.0138 0.0233 0.2426
Leishmania major phosphatidylinositol 3-related kinase, putative 0.047 0.0858 0.2338
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0041
Schistosoma mansoni ran 0.0023 0.0016 0.0076
Onchocerca volvulus 0.0016 0.0004 0.0058
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0016 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0004
Schistosoma mansoni lamin 0.0027 0.0024 0.0116
Brugia malayi Death domain containing protein 0.0015 0.0000078662 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.007 0.0479
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0016 0.0004 0.0026
Schistosoma mansoni semaphorin 5-related 0.014 0.0236 0.1158
Echinococcus multilocularis c src tyrosine kinase 0.0021 0.0013 0.0013
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0016 0.0004 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0181
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0376 0.068 0.4901
Leishmania major protein kinase, putative 0.002 0.001 0.0019
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0062 0.0089 0.09
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0024 0.0148
Brugia malayi Furin-like cysteine rich region family protein 0.0016 0.0004 0.0026
Schistosoma mansoni hypothetical protein 0.0107 0.0175 0.0857
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0009 0.0045
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.052 0.0951 0.6867
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0188 0.0326 0.2338
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.018 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0016 0.0004 0.0004
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0356 0.0643 0.4636
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0042 0.0052 0.0141
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0009 0.0045
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0062 0.0089 0.0248
Onchocerca volvulus 0.0107 0.0175 0.2898
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0013 0.0013
Plasmodium falciparum importin beta, putative 0.0031 0.0031 0.0851
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0029 0.0776
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0029 0.0282
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Echinococcus granulosus tyrosine protein kinase Blk 0.0021 0.0013 0.0013
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0042 0.1204
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0089 0.0618
Schistosoma mansoni tyrosine kinase 0.0021 0.0013 0.0064
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0034 0.0034
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.002 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0175 0.1242
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0335 0.0604 0.3336
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0075 0.0515
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0188 0.0326 0.2338
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0113 0.0113
Trypanosoma brucei cytochrome P450, putative 0.002 0.001 0.0063
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0016 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0032 0.0034 0.0244
Echinococcus multilocularis activin receptor type 0.002 0.001 0.001
Onchocerca volvulus 0.0039 0.0046 0.0753
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0122 0.0203 0.0578
Trichomonas vaginalis PIKK family atypical protein kinase 0.047 0.0858 0.619
Brugia malayi Protein kinase domain containing protein 0.0021 0.0013 0.0095
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0482 0.0881 0.636
Echinococcus granulosus tyrosine protein kinase csk 0.0016 0.0004 0.0004
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0061 0.0088 0.0613
Loa Loa (eye worm) hypothetical protein 0.0344 0.062 0.3425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.021 0.1495
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0041
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0009 0.0009
Plasmodium falciparum GAF domain-related protein, putative 0.002 0.001 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0000078662 0.0000000070971
Echinococcus granulosus activated cdc42 kinase 1 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.018 0.3966
Entamoeba histolytica protein kinase rad3, putative 0.0269 0.048 0.3451
Brugia malayi Importin beta-1 subunit 0.0031 0.0031 0.0224
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0138 0.0233 0.129
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0062 0.0089 0.0248
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0 0.0001
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0016 0.0113
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0107 0.0175 0.0857
Loa Loa (eye worm) TK/RYK protein kinase 0.0016 0.0004 0.002
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0107 0.0175 0.5313
Trypanosoma brucei polo-like protein kinase 0.0194 0.0338 0.3525
Loa Loa (eye worm) TK/ACK protein kinase 0.0016 0.0004 0.002
Plasmodium falciparum glycogen synthase kinase 3 0.0052 0.007 0.2051
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0016 0.0004 0.0004
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0048 0.0064 0.0351
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.0366 0.2022
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.002
Brugia malayi beta-lactamase family protein 0.0039 0.0046 0.0329
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0194 0.0338 0.0915
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0749 0.1383 1
Leishmania major hypothetical protein, unknown function 0.0107 0.0175 0.047
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Onchocerca volvulus 0.0016 0.0004 0.0058
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0016 0.0016
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0107 0.0175 0.0497
Brugia malayi IPT/TIG domain containing protein 0.0061 0.0088 0.0638
Echinococcus granulosus epidermal growth factor receptor 0.0016 0.0004 0.0004
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0024 0.0148
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0052 0.007 0.0193
Entamoeba histolytica serine/threonine protein kinase, putative 0.0194 0.0338 0.2421
Echinococcus granulosus kinase suppressor of Ras 1 0.0016 0.0004 0.0004
Loa Loa (eye worm) phosphatidylinositol kinase 0.0107 0.0175 0.0967
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Echinococcus multilocularis protein kinase 0.0016 0.0004 0.0004
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0009 0.0067
Echinococcus multilocularis heat shock protein 70 0.0016 0.0004 0.0004
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0749 0.1383 0.3997
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.0175 0.1265
Brugia malayi 6-phosphofructokinase 0.011 0.018 0.1298
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0009 0.0009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0194 0.0338 0.0337
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.031 0.0557 0.1603
Loa Loa (eye worm) hypothetical protein 0.0107 0.0175 0.0967
Echinococcus multilocularis 0.0107 0.0175 0.0175
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Echinococcus granulosus dual specificity testis-specific protein kinase 0.002 0.001 0.001
Brugia malayi DNA-binding protein LAG-1 0.0061 0.0088 0.0638
Entamoeba histolytica hypothetical protein 0.0627 0.1153 0.8328
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0029 0.0277
Leishmania major phosphatidylinositol 3-kinase, putative 0.0459 0.0837 0.2282
Echinococcus multilocularis kinase suppressor of Ras 1 0.0016 0.0004 0.0004
Echinococcus granulosus serine protein kinase ATM 0.0284 0.0508 0.0507
Loa Loa (eye worm) hypothetical protein 0.0165 0.0283 0.1566
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0004
Echinococcus granulosus tyrosine protein kinase Lyn 0.0025 0.002 0.0019
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0016 0.0004 0.0026
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0188 0.0326 0.0935
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0042 0.0107
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0042 0.1204
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.019 0.033 0.033
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0561 0.103 0.7437
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.028 0.05 0.3599
Echinococcus granulosus tyrosine protein kinase csk 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0021 0.0013 0.0095
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0016 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Plasmodium vivax importin-beta 2, putative 0.0031 0.0031 0.0851
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.031 0.0557 0.4009
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0188 0.0326 0.1802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0501 0.0916 0.6613
Onchocerca volvulus 0.0016 0.0004 0.0058
Schistosoma mansoni hypothetical protein 0.0036 0.0041 0.0202
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0065 0.032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0029 0.0142
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.052 0.0951 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0501 0.0916 0.6613
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0017
Echinococcus multilocularis serine protein kinase ATM 0.0284 0.0508 0.0507
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0052 0.007 0.0732
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.052 0.0951 0.6867
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Toxoplasma gondii target of rapamycin (TOR), putative 0.0496 0.0907 1
Loa Loa (eye worm) sema domain-containing protein 0.014 0.0236 0.1306
Schistosoma mansoni protein kinase 0.0017 0.0004 0.0018
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0142 0.0142
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.002 0.001 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.185 0.3456 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0107 0.0175 0.0967
Entamoeba histolytica hypothetical protein 0.0036 0.0041 0.0273
Schistosoma mansoni fibrocystin l 0.0061 0.0088 0.0432
Loa Loa (eye worm) hypothetical protein 0.014 0.0236 0.1306
Echinococcus granulosus retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Giardia lamblia Protein 21.1 0.0016 0.0004 0.000000074918
Onchocerca volvulus 0.0021 0.0013 0.0216
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0501 0.0916 0.9632
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0284 0.0508 0.2488
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Trichomonas vaginalis set domain proteins, putative 0.0238 0.042 0.3019
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0042 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Loa Loa (eye worm) phosphatidylinositol 3 0.047 0.0858 0.474
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0188 0.0326 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.017 0.0293 0.1435
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.047 0.0858 0.9015
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0016 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0107 0.0175 0.1242
Brugia malayi protein-tyrosine kinase 0.0021 0.0013 0.0095
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0126
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0544 0.0997 0.0997
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Schistosoma mansoni hypothetical protein 0.0061 0.0088 0.0432
Brugia malayi Protein kinase domain containing protein 0.0021 0.0013 0.0095
Schistosoma mansoni protein kinase 0.002 0.001 0.0049
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0009 0.0009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0041 0.0041
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0107 0.0175 0.1897
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0042 0.0702
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0325 0.0584 0.0584
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0046 0.2115
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0046 0.2115
Loa Loa (eye worm) TK/ALK protein kinase 0.0016 0.0004 0.002
Toxoplasma gondii ck2 beta subunit 0.0037 0.0042 0.043
Entamoeba histolytica hypothetical protein 0.0061 0.0088 0.0613
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0009 0.0009
Mycobacterium ulcerans lipase LipD 0.0039 0.0046 0.2115
Schistosoma mansoni tyrosine kinase 0.0021 0.0013 0.0064
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.052 0.0951 0.4661
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0188 0.0326 0.357
Onchocerca volvulus 0.0036 0.0041 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0075 0.0515
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.023 0.0406 0.4243
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0042 0.0052 0.035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0284 0.0508 0.3653
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0052 0.007 0.0341
Echinococcus granulosus high voltage activated calcium channel beta 0.0088 0.0138 0.0138
Onchocerca volvulus 0.0016 0.0004 0.0058
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0188 0.0326 0.2338
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.002
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0188 0.0326 0.0935
Echinococcus granulosus casein kinase ii subunit alpha 0.0138 0.0233 0.0233
Leishmania major casein kinase II, putative 0.0138 0.0233 0.063
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0016 0.0133
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0062 0.0089 0.0248
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.002
Trypanosoma cruzi cytochrome P450, putative 0.002 0.001 0.0018
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Brugia malayi Sema domain containing protein 0.014 0.0236 0.1708
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0016 0.0036
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0016 0.0004 0.0004
Leishmania major phosphatidylinositol kinase related protein, putative 0.0122 0.0203 0.0546
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0046 0.0837
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0252
Loa Loa (eye worm) plexin A 0.0396 0.0719 0.3974
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0017
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0017
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0061 0.0088 0.0613
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0029 0.0776
Echinococcus granulosus protein kinase 0.0016 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0009 0.0045
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0016 0.0004 0.0004
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.052 0.0951 0.0951
Echinococcus granulosus receptor type guanylyl cyclase 0.0016 0.0004 0.0004
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0181 0.0313 0.2262
Loa Loa (eye worm) TK/FAK protein kinase 0.0016 0.0004 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Trypanosoma cruzi protein kinase, putative 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0088 0.0488
Loa Loa (eye worm) sema domain-containing protein 0.014 0.0236 0.1306
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0749 0.1383 1
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0009 0.0041
Leishmania major importin beta-1 subunit, putative 0.0025 0.002 0.0046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0051
Onchocerca volvulus 0.0016 0.0004 0.0058
Brugia malayi Sema domain containing protein 0.014 0.0236 0.1708
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0306 0.055 0.3957
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0042 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0162 0.0277 0.1985
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0088 0.0138 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.052 0.0951 0.6867
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0358 0.0648 0.3174
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6296
Schistosoma mansoni single-minded 0.0049 0.0065 0.032
Echinococcus multilocularis semaphorin 5B 0.014 0.0236 0.0236
Echinococcus granulosus protein kinase shaggy 0.0052 0.007 0.007
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Brugia malayi Pre-SET motif family protein 0.0209 0.0366 0.2645
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0009 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0051
Brugia malayi Raf kinase 0.0016 0.0004 0.0026
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Brugia malayi hypothetical protein 0.014 0.0236 0.1708
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0021 0.0013 0.0013
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0009 0.0045
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0000078662 0.000000034792
Onchocerca volvulus 0.0021 0.0013 0.0216
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0088 0.0138 0.0137
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0009 0.0045
Brugia malayi phosphofructokinase 0.011 0.018 0.1298
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0052 0.007 0.0182
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Loa Loa (eye worm) gastrulation defective protein 1 0.0132 0.0221 0.1221
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0013 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0325 0.0584 0.2863
Mycobacterium tuberculosis Conserved protein 0.0039 0.0046 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0339 0.0611 0.4404
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0041 0.0041
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.018 0.1858
Brugia malayi 6-phosphofructokinase 0.011 0.018 0.1298
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0627 0.1153 0.8328
Trichomonas vaginalis PIKK family atypical protein kinase 0.028 0.05 0.3599
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.007 0.0479
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0284 0.0508 0.3669
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.033 0.0593 0.4275
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Brugia malayi intermediate filament protein 0.0027 0.0024 0.0171
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0107 0.0175 0.1897
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Brugia malayi beta-lactamase 0.0039 0.0046 0.0329
Echinococcus granulosus tyrosine kinase 0.0021 0.0013 0.0013
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.052 0.0951 0.0951
Brugia malayi hypothetical protein 0.0476 0.0869 0.6286
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0041
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0546 0.1001 0.7238
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0188 0.0326 0.1598
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0073
Schistosoma mansoni hypothetical protein 0.017 0.0293 0.1435
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.000000051443
Onchocerca volvulus Tyrosine kinase homolog 0.0016 0.0004 0.0058
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0062 0.0089 0.0435
Echinococcus granulosus 6 phosphofructokinase 0.011 0.018 0.018
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0013 0.0069
Echinococcus multilocularis natriuretic peptide receptor 1 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Entamoeba histolytica hypothetical protein 0.0061 0.0088 0.0613
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0181 0.0313 0.173
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0107 0.0175 0.1897
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0067 0.0327
Schistosoma mansoni importin beta-1 0.0031 0.0031 0.0152
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0107 0.0175 0.5313
Mycobacterium tuberculosis Conserved protein 0.0039 0.0046 0.0837
Echinococcus multilocularis transfer RNA-Thr 0.0016 0.0004 0.0004
Echinococcus multilocularis transcription factor collier 0.0061 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0195 0.034 0.1666
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0016 0.0004 0.0004
Plasmodium vivax unspecified product 0.0138 0.0233 0.7124
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0501 0.0916 0.2498
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0041
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0009 0.0009
Echinococcus multilocularis protein kinase shaggy 0.0052 0.007 0.007
Trichomonas vaginalis importin beta-1, putative 0.0025 0.002 0.0119
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0107 0.0175 0.0175
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0107 0.0175 0.5313
Onchocerca volvulus 0.0021 0.0013 0.0216
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0042 0.0208
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.051 0.0933 0.0933
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Trypanosoma cruzi target of rapamycin kinase 3 0.0501 0.0916 0.2644
Trichomonas vaginalis conserved hypothetical protein 0.0297 0.0532 0.3834
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0017
Onchocerca volvulus 0.0027 0.0024 0.0391
Loa Loa (eye worm) CYP4Cod1 0.002 0.001 0.0053
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0016 0.0004 0.0004
Echinococcus granulosus fibroblast growth factor receptor 4 0.0016 0.0004 0.0004
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0349 0.0629 0.4551
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0107 0.0175 0.1242
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0031 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0046 0.0223
Echinococcus granulosus retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Plasmodium vivax glycogen synthase kinase 3, putative 0.0052 0.007 0.2051
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Onchocerca volvulus 0.005 0.0067 0.1106
Brugia malayi Guanylyl cyclase protein 23 0.0016 0.0004 0.0026
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0107 0.0175 0.0497
Brugia malayi C-terminal src kinase protein 1 0.0016 0.0004 0.0026
Leishmania major phosphatidylinositol kinase, putative 0.0107 0.0175 0.047
Brugia malayi hypothetical protein 0.0016 0.0004 0.0026
Brugia malayi beta-lactamase family protein 0.0039 0.0046 0.0329
Echinococcus multilocularis high voltage activated calcium channel beta 0.0088 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0177 0.0305 0.1687
Onchocerca volvulus 0.0102 0.0164 0.2716
Loa Loa (eye worm) phosphatidylinositol 3 0.0107 0.0175 0.0967
Echinococcus multilocularis epidermal growth factor receptor 0.0016 0.0004 0.0004
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0016 0.0086
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0021 0.0013 0.0013
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0009 0.0067
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0749 0.1383 1
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0046 0.0837
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0138 0.0233 0.7124
Loa Loa (eye worm) TK/Met protein kinase 0.0016 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0061 0.0088 0.0488
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0005 0.0022
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0029 0.0776
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0042 0.0282
Onchocerca volvulus 0.0027 0.0024 0.0391
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0016 0.0004 0.0004
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0042 0.1204
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.002 0.001 0.0007
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0188 0.0326 0.0326
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0107 0.0175 0.0175
Echinococcus granulosus semaphorin 5B 0.014 0.0236 0.0236
Plasmodium vivax SET domain protein, putative 0.003 0.0029 0.0791
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0325 0.0584 0.3228
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0024 0.0173
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0156 0.1105
Echinococcus granulosus activin receptor type 0.002 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0036 0.0041 0.0273
Brugia malayi hypothetical protein 0.0102 0.0164 0.1187
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0046 0.0252
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.052 0.0951 0.6867
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0024 0.0131
Loa Loa (eye worm) TK protein kinase 0.0021 0.0013 0.0073
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0239 0.0423 0.2336
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0016 0.0004 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0252
Echinococcus granulosus single minded 2 0.0036 0.0041 0.0041
Echinococcus granulosus tyrosine protein kinase 0.0016 0.0004 0.0004
Schistosoma mansoni protein kinase 0.0138 0.0233 0.1144
Mycobacterium ulcerans putative regulatory protein 0.002 0.001 0.0007
Echinococcus granulosus epidermal growth factor receptor 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0029 0.0142
Schistosoma mansoni tyrosine kinase 0.0021 0.0013 0.0064
Entamoeba histolytica protein kinase, putative 0.0052 0.007 0.0479
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0107 0.0175 0.0857
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0188 0.0326 0.2338
Onchocerca volvulus 0.0039 0.0046 0.0753
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.018 0.1276
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0032 0.0034 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0186
Loa Loa (eye worm) phosphatidylinositol 3 0.0976 0.1809 1
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.002 0.0119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.031 0.0557 0.4025
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0061 0.0088 0.0613
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0032 0.0034 0.0034
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0034 0.0034
Schistosoma mansoni lamin 0.0027 0.0024 0.0116
Entamoeba histolytica protein kinase domain containing protein 0.002 0.001 0.0047
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0029 0.0181
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0102 0.0164 0.0906
Toxoplasma gondii CMGC kinase, CK2 family 0.0138 0.0233 0.2543
Onchocerca volvulus 0.0021 0.0013 0.0216
Entamoeba histolytica hypothetical protein 0.0284 0.0508 0.3653
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0046 0.0123
Brugia malayi Probable exocyst complex component Sec5 0.0061 0.0088 0.0638
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0017
Brugia malayi serine/threonine-protein kinase plk-2 0.0194 0.0338 0.244
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0252
Echinococcus multilocularis tyrosine protein kinase pr2 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Echinococcus granulosus retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0061 0.0088 0.0613
Schistosoma mansoni hypothetical protein 0.0082 0.0128 0.0627
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Brugia malayi Plexin repeat family protein 0.0335 0.0604 0.4364
Echinococcus granulosus tyrosine protein kinase Srms 0.0021 0.0013 0.0013
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.052 0.0951 0.2745
Trichomonas vaginalis PIKK family atypical protein kinase 0.0459 0.0837 0.6042
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0016 0.0127
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.018 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.051 0.0933 0.2693
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.051 0.0933 0.0933
Loa Loa (eye worm) TK/ABL protein kinase 0.0021 0.0013 0.0073
Brugia malayi Pre-SET motif family protein 0.003 0.0029 0.021
Leishmania major cytochrome p450-like protein 0.002 0.001 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0029 0.0142
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Mycobacterium ulcerans putative regulatory protein 0.002 0.001 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0004 0.0026
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Loa Loa (eye worm) RecQ helicase 0.0021 0.0013 0.0072
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Onchocerca volvulus 0.0238 0.042 0.6964
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0032 0.0034 0.0034
Echinococcus multilocularis tyrosine kinase 0.0021 0.0013 0.0013
Giardia lamblia Kinase, CMGC GSK 0.0052 0.007 0.0698
Entamoeba histolytica hypothetical protein 0.0036 0.0041 0.0273
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.007 0.0479
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0041 0.1861
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0046 0.0304
Echinococcus multilocularis ephrin type A receptor 4 A 0.0016 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.052 0.0951 0.6875
Giardia lamblia Phosphatidylinositol 4-kinase 0.0107 0.0175 0.1809
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0046 0.0304
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0029 0.0181
Echinococcus multilocularis snurportin 1 0.0331 0.0595 0.0595
Schistosoma mansoni hypothetical protein 0.014 0.0236 0.1158
Onchocerca volvulus 0.0335 0.0604 1
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Echinococcus granulosus lamin 0.0027 0.0024 0.0024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0749 0.1383 1
Schistosoma mansoni survival motor neuron protein 0.0097 0.0156 0.0762
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Loa Loa (eye worm) protein kinase domain-containing protein 0.0016 0.0004 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0181
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0009 0.0009
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0009 0.0009
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0107 0.0175 0.1242
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.000000051443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0162 0.0277 0.1985
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0013 0.0094
Trypanosoma cruzi protein kinase, putative 0.0016 0.0004 0.0001
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0188 0.0326 0.0884
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0088 0.0613
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0045
Loa Loa (eye worm) hypothetical protein 0.005 0.0067 0.0369
Trypanosoma brucei protein kinase, putative 0.002 0.001 0.0068
Schistosoma mansoni intermediate filament proteins 0.0027 0.0024 0.0116
Echinococcus multilocularis plexin a4 0.0396 0.0719 0.0719
Entamoeba histolytica tyrosin kinase, putative 0.0078 0.0119 0.0837
Schistosoma mansoni hypothetical protein 0.0331 0.0595 0.2919
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Echinococcus granulosus transcription factor collier 0.0061 0.0088 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0017
Schistosoma mansoni hypothetical protein 0.014 0.0236 0.1158
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.052 0.0951 0.2745
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0021 0.0013 0.0013
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.051 0.0933 0.2693
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0016 0.0076
Schistosoma mansoni serine/threonine RGC 0.0016 0.0004 0.0017
Mycobacterium leprae Probable lipase LipE 0.0039 0.0046 0.2109
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus tyrosine kinase 0.0021 0.0013 0.0013
Echinococcus granulosus tyrosine kinase 0.0016 0.0004 0.0004
Echinococcus granulosus expressed protein 0.0377 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0251 0.0446 0.2463
Brugia malayi M-phase phosphoprotein, mpp8 0.0102 0.0164 0.1186
Loa Loa (eye worm) calcium channel 0.0032 0.0034 0.0186
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.0001
Loa Loa (eye worm) SRC-1 0.0021 0.0013 0.0073
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Loa Loa (eye worm) TK/DDR protein kinase 0.0016 0.0004 0.002
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0016 0.0004 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0501 0.0916 0.6613
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0042 0.0282
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0013 0.0013
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0042 0.0052 0.035
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0194 0.0338 0.1866
Plasmodium vivax hypothetical protein, conserved 0.0107 0.0175 0.5313
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0016 0.0004 0.0004
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0016 0.0076
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0004 0.0004
Brugia malayi Cytochrome P450 family protein 0.003 0.0029 0.0211
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0029 0.0277
Loa Loa (eye worm) beta-lactamase 0.0039 0.0046 0.0252
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0045
Schistosoma mansoni protein kinase 0.002 0.001 0.0049
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6296
Schistosoma mansoni 6-phosphofructokinase 0.011 0.018 0.088
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Echinococcus granulosus intermediate filament protein 0.0027 0.0024 0.0024
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0031 0.0304
Toxoplasma gondii hypothetical protein 0.002 0.001 0.0068
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.000000051443
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0062 0.0089 0.0618
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0181
Brugia malayi Protein kinase domain containing protein 0.0021 0.0013 0.0095
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.0089 0.0618
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0297 0.0532 0.5854
Echinococcus granulosus natriuretic peptide receptor 1 0.0016 0.0004 0.0004
Brugia malayi FAT domain containing protein 0.019 0.033 0.2388
Brugia malayi SRC-1 0.0021 0.0013 0.0095
Loa Loa (eye worm) TK/EGFR protein kinase 0.0016 0.0004 0.002
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0269 0.048 0.048
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0029 0.5
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1098 0.204 0.204
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0284 0.0508 0.532
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Leishmania major GTP-binding protein, putative 0.0023 0.0016 0.0034
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0009 0.0045
Entamoeba histolytica hypothetical protein 0.0061 0.0088 0.0613
Echinococcus granulosus voltage dependent calcium channel 0.0032 0.0034 0.0034
Echinococcus granulosus tyrosine protein kinase csk 0.0016 0.0004 0.0004
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0024 0.0173
Trypanosoma cruzi cytochrome P450, putative 0.002 0.001 0.0018
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0041
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0107 0.0175 0.1809
Loa Loa (eye worm) phosphatidylinositol 3 0.0107 0.0175 0.0967
Echinococcus granulosus plexin a4 0.0396 0.0719 0.0719
Echinococcus granulosus insulin receptor 0.0016 0.0004 0.0004
Loa Loa (eye worm) TK/EPH protein kinase 0.0016 0.0004 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0181
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0252
Entamoeba histolytica hypothetical protein 0.0025 0.002 0.0119
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0045
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0013 0.0013
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0107 0.0175 0.0857
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0029 0.0264
Schistosoma mansoni fkbp-rapamycin associated protein 0.0269 0.048 0.2351
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0075 0.0515
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0008 0.0141
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0188 0.0326 0.3405
Loa Loa (eye worm) hypothetical protein 0.019 0.033 0.1825
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0042 0.0702
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus protein tyrosine kinase 0.0016 0.0004 0.0004
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0013 0.0064
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0046 0.0837
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0269 0.048 0.138
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0034 0.0034
Trypanosoma cruzi polo-like protein kinase, putative 0.0194 0.0338 0.0968
Echinococcus multilocularis raf serine:threonine protein kinase 0.0016 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.1958 0.3658 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Entamoeba histolytica phosphofructokinase, putative 0.011 0.018 0.1276
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.000000051443
Loa Loa (eye worm) hypothetical protein 0.014 0.0236 0.1306
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0017
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Brugia malayi hypothetical protein 0.014 0.0236 0.1708
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0062 0.0089 0.0089
Loa Loa (eye worm) phosphofructokinase 0.011 0.018 0.0993
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0013 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.018 0.1276
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0013 0.0013
Onchocerca volvulus 0.0097 0.0156 0.2577
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0284 0.0508 0.1461
Brugia malayi plexin A 0.0396 0.0719 0.5199
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0042 0.0042
Echinococcus multilocularis protein kinase 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0561 0.103 0.7437
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0042 0.043
Entamoeba histolytica hypothetical protein 0.0036 0.0041 0.0273
Echinococcus multilocularis geminin 0.017 0.0293 0.0293
Onchocerca volvulus 0.0016 0.0004 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0051 0.0248
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0013 0.0013
Trichomonas vaginalis ran, putative 0.0023 0.0016 0.0087
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0034 0.0034
Toxoplasma gondii GAF domain-containing protein 0.002 0.001 0.0068
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0016 0.0004 0.0017
Giardia lamblia Casein kinase II beta chain 0.0037 0.0042 0.041
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0009 0.0051
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.0438 1
Entamoeba histolytica Ran family GTPase 0.0023 0.0016 0.0087
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0325 0.0584 0.0584
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0188 0.0326 0.1598
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0009 0.0009
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0004 0.0017
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Entamoeba histolytica hypothetical protein 0.0107 0.0175 0.1242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0459 0.0837 0.6042
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0016 0.0004 0.0004
Brugia malayi hypothetical protein 0.0165 0.0283 0.2049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0459 0.0837 0.6042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.001 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Echinococcus multilocularis musashi 0.0027 0.0024 0.0024
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0135 0.0227 0.1257
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0054
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0107 0.0175 0.0175
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0029 0.0029
Toxoplasma gondii ABC1 family protein 0.0039 0.0046 0.0464
Echinococcus multilocularis insulin receptor 0.0016 0.0004 0.0004
Echinococcus multilocularis integrin linked protein kinase 0.0016 0.0004 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Plasmodium vivax hypothetical protein, conserved 0.002 0.001 0.019
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.031 0.0557 0.4009
Echinococcus multilocularis lamin 0.0027 0.0024 0.0024
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0062 0.0089 0.0089
Loa Loa (eye worm) TK/CSK protein kinase 0.0016 0.0004 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0046 0.0304
Loa Loa (eye worm) phosphatidylinositol 3 0.0107 0.0175 0.0967
Brugia malayi SH2 domain containing protein 0.0021 0.0013 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0482 0.0881 0.636
Onchocerca volvulus 0.0041 0.0051 0.0838
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0032 0.0034 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0046 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0501 0.0916 0.6613
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0316 0.0567 0.5953
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0046 0.0123
Onchocerca volvulus 0.0016 0.0004 0.0058
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0013 0.0068
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.001 0.002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.000000051443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0496 0.0907 0.6549
Echinococcus multilocularis protein tyrosine kinase 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Conserved protein 0.0039 0.0046 0.0837
Brugia malayi Protein kinase domain containing protein 0.0135 0.0227 0.1644
Schistosoma mansoni plexin 0.0195 0.034 0.1666
Echinococcus multilocularis dual specificity testis specific protein kinase 0.002 0.001 0.001
Echinococcus multilocularis casein kinase ii subunit alpha 0.0138 0.0233 0.0233
Brugia malayi Cytochrome P450 family protein 0.002 0.001 0.0069
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Echinococcus granulosus c src tyrosine kinase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.002
Schistosoma mansoni hypothetical protein 0.0052 0.007 0.0345
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0029 0.0162
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0062 0.0089 0.0618
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.000000051443
Onchocerca volvulus 0.0021 0.0013 0.0216
Schistosoma mansoni tyrosine kinase 0.0021 0.0013 0.0064
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0021 0.0013 0.0013
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0227 0.1114
Schistosoma mansoni tyrosine protein kinase 0.0016 0.0004 0.0017
Schistosoma mansoni voltage-gated cation channel 0.0032 0.0034 0.0165
Echinococcus granulosus raf serine:threonine protein kinase 0.0016 0.0004 0.0004
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0009 0.0009
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0024 0.0117
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0175 0.1242
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.031 0.0557 0.4009
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0203 0.0355 0.1017
Echinococcus granulosus ephrin type A receptor 4 A 0.0016 0.0004 0.0004
Echinococcus multilocularis survival motor neuron protein 1 0.0476 0.0869 0.0869
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0016 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.051 0.0933 0.6745
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0233 0.1666
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0026
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0325 0.0584 0.9678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0311 0.0558 0.4021
Loa Loa (eye worm) hypothetical protein 0.014 0.0236 0.1306
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0042 0.0042
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0029 0.0277
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0107 0.0175 0.5313
Toxoplasma gondii FATC domain-containing protein 0.0284 0.0508 0.5578
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0439 0.0799 0.8396
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0107 0.0175 0.0497
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0013 0.0013
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0041 0.0202
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0004 0.0026
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0194 0.0338 0.0337
Onchocerca volvulus 0.0021 0.0013 0.0216
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0107 0.0175 0.1809
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0052 0.007 0.0385
Brugia malayi integrin-linked kinase 0.0016 0.0004 0.0026
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0089 0.0618
Echinococcus multilocularis expressed protein 0.0377 0.0683 0.0683
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0156 0.1125
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0113 0.0113
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0016 0.0374
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0009 0.0009
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0061 0.0088 0.0613
Trypanosoma cruzi casein kinase II, putative 0.0138 0.0233 0.0667
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0029 0.0776
Echinococcus multilocularis epidermal growth factor receptor 0.0016 0.0004 0.0004
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0042 0.0282
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0031 0.029
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.018 0.018
Brugia malayi PXA domain containing protein 0.0021 0.0012 0.0086
Loa Loa (eye worm) phosphatidylinositol 3 0.0203 0.0355 0.1959
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0016 0.0086
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0046 0.0045
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0052 0.007 0.007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0021 0.0013 0.0095
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.052 0.0951 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0269 0.048 0.3451
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0045
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0107 0.0175 0.0497
Giardia lamblia Kinase, CMGC GSK 0.0052 0.007 0.0698
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0041 0.0298
Leishmania major hypothetical protein, conserved 0.0039 0.0046 0.0116
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0013 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6296
Echinococcus granulosus tyrosine protein kinase ABL1 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0131
Loa Loa (eye worm) TK/INSR protein kinase 0.0016 0.0004 0.002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0016 0.0127
Echinococcus granulosus snurportin 1 0.0331 0.0595 0.0595
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0046 0.2109
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0338 0.2421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6295
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0017
Leishmania major phosphatidylinositol 4-kinase, putative 0.0107 0.0175 0.047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0478 0.0872 0.6295
Echinococcus multilocularis tyrosine protein kinase Blk 0.0021 0.0013 0.0013
Brugia malayi hypothetical protein 0.0021 0.0013 0.0095
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0749 0.1383 0.3997
Echinococcus multilocularis tyrosine protein kinase 0.0016 0.0004 0.0004
Brugia malayi Uncoordinated protein 44 0.0015 0.0000078662 0.0001
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0016 0.0004 0.0017
Entamoeba histolytica cell surface protease gp63, putative 0.0061 0.0088 0.0613
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0016 0.0004 0.0017
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.052 0.0951 0.6867
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0188 0.0326 1
Toxoplasma gondii hypothetical protein 0.002 0.001 0.0068
Echinococcus multilocularis receptor type guanylyl cyclase 0.0016 0.0004 0.0004

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 43.4 % In vitro inhibition of glucan synthase obtained from C. albicans at a concentration of 10 ug/mL. ChEMBL. 7650681
MIC (functional) > 20 ug ml-1 Antifungal activity against Candida albicans ChEMBL. 7650681

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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