Detailed information for compound 2072414

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 308.378 | Formula: C18H20N4O
  • H donors: 1 H acceptors: 2 LogP: 2.7 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)cc([nH]2)C(=O)N1CCCC1Cn1cccn1
  • InChi: 1S/C18H20N4O/c1-13-5-6-16-14(10-13)11-17(20-16)18(23)22-9-2-4-15(22)12-21-8-3-7-19-21/h3,5-8,10-11,15,20H,2,4,9,12H2,1H3
  • InChiKey: ZKMQCBJMFPRVPY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.012
Echinococcus granulosus histone deacetylase 0.0018 0.0014 0.0014
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0137 0.022 0.4834
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0023 0.0022 0.0328
Brugia malayi Trypsin family protein 0.158 0.2712 1
Schistosoma mansoni ran 0.0013 0.0005 0.0011
Brugia malayi Zona pellucida-like domain containing protein 0.0101 0.0157 0.058
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0151
Onchocerca volvulus 0.0014 0.0008 0.0029
Trypanosoma cruzi WLM domain containing protein, putative 0.0137 0.022 0.4834
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0022 0.0082
Schistosoma mansoni cpg binding protein 0.002 0.0017 0.0041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Onchocerca volvulus 0.0029 0.0033 0.0123
Onchocerca volvulus Alhambra homolog 0.0018 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0849 0.1449 0.5344
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0118 0.0186 0.0456
Brugia malayi ecdysteroid receptor 0.0019 0.0015 0.0057
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0022 0.0328
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0014 0.0008 0.0029
Trypanosoma brucei histone deacetylase 3 0.0018 0.0014 0.0315
Onchocerca volvulus 0.0137 0.022 0.081
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0008 0.0008
Toxoplasma gondii PAN/Apple domain-containing protein 0.0023 0.0022 0.0328
Brugia malayi phosphofructokinase 0.0091 0.014 0.0518
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0027 0.003 0.0659
Brugia malayi 6-phosphofructokinase 0.0091 0.014 0.0518
Onchocerca volvulus 0.0283 0.0473 0.1743
Schistosoma mansoni polycystin 1-related 0.0018 0.0013 0.0033
Brugia malayi Pre-SET motif family protein 0.0175 0.0285 0.1052
Echinococcus multilocularis histone deacetylase 1 0.0014 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0567 0.0962 1
Schistosoma mansoni inositol monophosphatase 0.0042 0.0055 0.0136
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0014 0.0035
Onchocerca volvulus Putative nachr subunit 0.0014 0.0008 0.0029
Toxoplasma gondii pyruvate kinase PyK1 0.0042 0.0056 0.0845
Echinococcus granulosus pyruvate kinase 0.0022 0.002 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0015 0.0037
Loa Loa (eye worm) MH2 domain-containing protein 0.0112 0.0177 0.0652
Schistosoma mansoni axis inhibition protein axin 0.0017 0.0013 0.0031
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Echinococcus granulosus Zinc finger RanBP2 type 0.0137 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0109 0.0172 0.0634
Echinococcus granulosus pyruvate kinase 0.0042 0.0056 0.0056
Entamoeba histolytica acyl-CoA synthetase, putative 0.003 0.0035 0.2151
Echinococcus multilocularis SWI:SNF matrix associated 0.0385 0.0648 0.0648
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0007 0.0073
Schistosoma mansoni 6-phosphofructokinase 0.0091 0.014 0.0344
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0385 0.0648 1
Echinococcus multilocularis neuropeptide receptor A26 0.0585 0.0993 0.0993
Brugia malayi regulator of G-protein signaling rgs-7 0.0017 0.0013 0.0046
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.158 0.2712 0.6647
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0013 0.0131
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.008
Onchocerca volvulus 0.0567 0.0962 0.3546
Brugia malayi glutaminase DH11.1 0.0515 0.0873 0.3221
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0076 0.0114 0.0419
Echinococcus multilocularis chromobox protein 1 0.0022 0.0022 0.0022
Loa Loa (eye worm) pyruvate kinase 0.0042 0.0056 0.0206
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0022 0.0328
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Toxoplasma gondii histone deacetylase HDAC3 0.0014 0.0007 0.0098
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0128
Plasmodium vivax multidomain scavenger receptor, putative 0.0018 0.0013 0.0135
Brugia malayi Immunoglobulin I-set domain containing protein 0.0101 0.0157 0.058
Schistosoma mansoni hypothetical protein 0.0265 0.044 0.1078
Loa Loa (eye worm) hypothetical protein 0.0069 0.0103 0.038
Onchocerca volvulus 0.0253 0.042 0.1548
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0017
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0043 0.0056 0.0854
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0197 0.0323 0.1193
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0008 0.0029
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0008 0.0008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0008 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0005
Brugia malayi SWIB/MDM2 domain containing protein 0.0385 0.0648 0.2391
Plasmodium vivax pyruvate kinase, putative 0.0042 0.0056 0.0794
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0017 0.0013 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0013 0.0131
Schistosoma mansoni hypothetical protein 0.0109 0.0172 0.0421
Schistosoma mansoni hypothetical protein 0.0098 0.0153 0.0374
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Schistosoma mansoni hypothetical protein 0.0385 0.0648 0.1589
Loa Loa (eye worm) hypothetical protein 0.1095 0.1874 0.691
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0008 0.0029
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0128 0.0204 0.0204
Loa Loa (eye worm) pyruvate kinase-PB 0.0029 0.0034 0.0124
Schistosoma mansoni hypothetical protein 0.1277 0.2189 0.5365
Schistosoma mansoni hypothetical protein 0.0567 0.0962 0.2357
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Mycobacterium tuberculosis Probable esterase LipL 0.0034 0.0041 0.043
Onchocerca volvulus 0.0034 0.0041 0.0151
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0109 0.0172 0.0634
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.0135
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0197 0.0323 0.1193
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0137 0.022 0.4834
Onchocerca volvulus 0.0101 0.0157 0.058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Loa Loa (eye worm) RNA binding protein 0.0119 0.0189 0.0698
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Loa Loa (eye worm) hypothetical protein 0.0567 0.0962 0.3546
Echinococcus granulosus tissue type plasminogen activator 0.0098 0.0153 0.0153
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0567 0.0962 0.2357
Entamoeba histolytica phosphofructokinase, putative 0.0091 0.014 0.8916
Plasmodium falciparum phd finger protein, putative 0.0018 0.0014 0.0149
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0035 0.0361
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0008 0.0008
Onchocerca volvulus 0.0098 0.0153 0.0564
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0043 0.0056 1
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0015 0.0037
Toxoplasma gondii hypothetical protein 0.0023 0.0022 0.0328
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0022 0.0328
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0385 0.0648 0.1589
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Brugia malayi A-kinase anchor protein 10, precursor 0.0017 0.0013 0.0046
Brugia malayi metabotropic glutamate receptor type 2 0.0353 0.0593 0.2185
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0051 0.0071 0.0174
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0137 0.022 0.4834
Echinococcus granulosus acetylcholinesterase 0.0051 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0101 0.0157 0.0386
Brugia malayi hypothetical protein 0.0567 0.0962 0.3546
Schistosoma mansoni metabotropic glutamate receptor 0.0589 0.1 0.2452
Brugia malayi 6-phosphofructokinase 0.0091 0.014 0.0518
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0015 0.0057
Echinococcus granulosus Regulator of G protein signaling 20 0.0017 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0015 0.0057
Trichomonas vaginalis pyruvate kinase, putative 0.0042 0.0056 0.0627
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0101 0.0157 0.058
Onchocerca volvulus 0.0101 0.0157 0.058
Brugia malayi Cation transporter family protein 0.0014 0.0008 0.0029
Entamoeba histolytica pyruvate kinase, putative 0.0029 0.0034 0.2089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0118 0.0186 0.0456
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0043 0.0056 0.0803
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0064
Toxoplasma gondii proteasome subunit beta type, putative 0.0042 0.0056 0.0844
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0033 0.004 0.0884
Trypanosoma brucei hypothetical protein, conserved 0.0137 0.022 0.4834
Loa Loa (eye worm) pyruvate kinase 0.0042 0.0056 0.0206
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0137 0.022 0.081
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0035 0.0044 0.0107
Brugia malayi PXA domain containing protein 0.0017 0.0013 0.0046
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0015 0.0037
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0027 0.0027
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0014 0.0008 0.0008
Giardia lamblia Histone deacetylase 0.0014 0.0007 0.0539
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.002 0.0017 0.0064
Chlamydia trachomatis pyruvate kinase 0.0042 0.0056 0.0545
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0017 0.0012 0.003
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0013 0.0031
Onchocerca volvulus Poor gastrulation protein homolog 0.0109 0.0172 0.0634
Onchocerca volvulus 0.0101 0.0157 0.058
Loa Loa (eye worm) acetylcholinesterase 1 0.0051 0.0071 0.0263
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0091 0.014 0.2201
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0216 0.0356 0.0356
Onchocerca volvulus 0.0849 0.1449 0.5344
Schistosoma mansoni brg-1 associated factor 0.0385 0.0648 0.1589
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0077 0.0117 0.0431
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0015 0.0057
Onchocerca volvulus 0.0034 0.0042 0.0156
Schistosoma mansoni hypothetical protein 0.0085 0.013 0.0318
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0088 0.0134 0.0496
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0048 0.0272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0027 0.0066
Treponema pallidum 76K protein 0.0101 0.0157 0.0152
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0014 0.0008 0.0019
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0337 0.0565 0.0565
Echinococcus granulosus histone deacetylase 3 0.0014 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0272
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0014 0.0149
Brugia malayi YY1-associated factor 2 0.0137 0.022 0.081
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0017 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.008
Echinococcus granulosus peregrin 0.0018 0.0014 0.0014
Toxoplasma gondii microneme protein MIC17A 0.0023 0.0022 0.0328
Trichomonas vaginalis ran, putative 0.0013 0.0005 0.0041
Trichomonas vaginalis importin beta-1, putative 0.0014 0.0007 0.0066
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0137 0.022 0.081
Toxoplasma gondii histone lysine methyltransferase SET1 0.0036 0.0045 0.0683
Onchocerca volvulus 0.0023 0.0022 0.0082
Echinococcus multilocularis regulator of G protein signaling 3 0.0017 0.0013 0.0012
Brugia malayi Carboxylesterase family protein 0.0051 0.0071 0.0262
Entamoeba histolytica hypothetical protein, conserved 0.0101 0.0157 1
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0014 0.0008 0.0029
Leishmania major hypothetical protein, conserved 0.0137 0.022 0.4834
Leishmania major ATP-dependent phosphofructokinase 0.0091 0.014 0.3091
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0253 0.042 0.1029
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Echinococcus granulosus endothelin converting enzyme 1 0.0069 0.0103 0.0103
Loa Loa (eye worm) TK/ROR protein kinase 0.0098 0.0153 0.0564
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.003 0.0331
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0025 0.0025 0.028
Loa Loa (eye worm) glutamate receptor 0.0698 0.1189 0.4386
Schistosoma mansoni glutamate receptor AMPA 0.0128 0.0204 0.0501
Brugia malayi Importin beta-1 subunit 0.0017 0.0012 0.0046
Echinococcus granulosus Squalene phytoene synthase 0.0085 0.013 0.013
Echinococcus granulosus regulator of G protein signaling 3 0.0017 0.0013 0.0012
Plasmodium falciparum carbonic anhydrase 0.0029 0.0033 0.0435
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0027 0.0066
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0008 0.0008
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0014 0.0008 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0118 0.0186 0.0186
Mycobacterium leprae conserved hypothetical protein 0.0034 0.0041 0.0127
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0118 0.0186 0.0186
Schistosoma mansoni cpg binding protein 0.0019 0.0015 0.0037
Echinococcus multilocularis acetylcholinesterase 0.0051 0.0071 0.0071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0041 0.01
Trypanosoma cruzi squalene synthase, putative 0.0273 0.0454 1
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0041 0.0898
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.3537
Echinococcus multilocularis carbonic anhydrase 0.0029 0.0033 0.0033
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.003 0.0035 0.0361
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0042 0.0056 0.1227
Loa Loa (eye worm) peptidase family M13 containing protein 0.0051 0.0072 0.0264
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0047 0.0065 0.0065
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0055 0.1219
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0337 0.0565 0.0565
Toxoplasma gondii histone deacetylase HDAC1 0.0018 0.0014 0.0204
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0041 0.01
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0014 0.0035
Mycobacterium ulcerans fatty-acid-CoA ligase 0.003 0.0035 0.0361
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.012
Brugia malayi PXA domain containing protein 0.0017 0.0013 0.0046
Echinococcus granulosus glutamate receptor 2 0.0216 0.0356 0.0356
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0567 0.0962 0.0962
Echinococcus multilocularis RUN 0.0018 0.0013 0.0013
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0385 0.0648 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0034 0.0041 0.0151
Echinococcus multilocularis glutamate receptor 2 0.0128 0.0204 0.0204
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0018 0.0014 0.0035
Brugia malayi MAP kinase sur-1 0.0027 0.003 0.011
Echinococcus multilocularis snurportin 1 0.0182 0.0298 0.0298
Loa Loa (eye worm) histone deacetylase 1 0.0014 0.0007 0.0027
Schistosoma mansoni hypothetical protein 0.0018 0.0013 0.0033
Giardia lamblia PHD finger protein 15 0.0018 0.0014 0.1872
Schistosoma mansoni hypothetical protein 0.0137 0.022 0.0538
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.003 0.0331
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0017 0.0012 0.003
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0098 0.0153 0.2302
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0008 0.0029
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0151 0.0244 0.09
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0101 0.0157 0.2372
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0385 0.0648 0.2391
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0015 0.0037
Brugia malayi Glutamate receptor 1 precursor 0.0128 0.0204 0.0753
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0085 0.013 0.0479
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.003 0.0035 0.0307
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0189 0.0464
Trichomonas vaginalis phosphofructokinase, putative 0.0025 0.0025 0.028
Loa Loa (eye worm) hypothetical protein 0.0567 0.0962 0.3546
Loa Loa (eye worm) CUTiclin family member 0.0101 0.0157 0.058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Loa Loa (eye worm) trypsin family protein 0.0567 0.0962 0.3546
Echinococcus multilocularis cpg binding protein 0.002 0.0017 0.0017
Schistosoma mansoni cellular tumor antigen P53 0.0849 0.1449 0.3552
Onchocerca volvulus 0.0023 0.0022 0.0082
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0014 0.0203
Brugia malayi Matrixin family protein 0.0253 0.042 0.1548
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0047 0.0065 0.0065
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.004 0.0418
Toxoplasma gondii kringle domain-containing protein 0.0098 0.0153 0.2344
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0047 0.0065 0.0065
Schistosoma mansoni glutamate receptor kainate 0.0249 0.0413 0.1013
Schistosoma mansoni hypothetical protein 0.0043 0.0057 0.014
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0055 0.3473
Loa Loa (eye worm) carbonic anhydrase 3 0.0077 0.0117 0.0431
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0013 0.0013
Trypanosoma brucei importin beta-1 subunit, putative 0.0017 0.0012 0.0275
Plasmodium falciparum importin beta, putative 0.0017 0.0012 0.0121
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.008
Echinococcus granulosus lysine specific demethylase 5A 0.0023 0.0023 0.0023
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0056 0.0451
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0027 0.0398
Trypanosoma brucei histone deacetylase 1 0.0014 0.0007 0.0164
Entamoeba histolytica acyl-coA synthetase, putative 0.003 0.0035 0.2151
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0015 0.0057
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0013 0.0005 0.0005
Trypanosoma brucei protein kinase, putative 0.0027 0.003 0.0659
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0049 0.0068 0.0068
Echinococcus granulosus survival motor neuron protein 1 0.0289 0.0482 0.0482
Leishmania major carbonic anhydrase-like protein 0.0077 0.0117 0.2571
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0091 0.014 0.2441
Schistosoma mansoni glutamate receptor kainate 0.0128 0.0204 0.0501
Echinococcus granulosus GPCR family 2 0.002 0.0017 0.0017
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0008 0.0029
Echinococcus granulosus voltage dependent calcium channel subunit 0.2473 0.4254 0.4254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0063 0.0092 0.0339
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0043 0.0056 0.0744
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0189 0.0464
Leishmania major pyruvate kinase 0.0042 0.0056 0.1228
Mycobacterium ulcerans lipase LipD 0.0034 0.0041 0.0424
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Entamoeba histolytica hypothetical protein 0.0017 0.0013 0.0731
Loa Loa (eye worm) hypothetical protein 0.0106 0.0165 0.061
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0008 0.0019
Echinococcus multilocularis Polycystic kidney disease protein 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Echinococcus granulosus nmda type glutamate receptor 0.0047 0.0065 0.0065
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0008 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.0053 0.0129
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0118 0.0186 0.0686
Loa Loa (eye worm) latrophilin receptor protein 2 0.002 0.0017 0.0064
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.002 0.0017 0.0017
Plasmodium vivax pyruvate kinase 2, putative 0.0022 0.002 0.0243
Brugia malayi jmjC domain containing protein 0.0023 0.0023 0.0084
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0017 0.0012 0.003
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0162 0.0262 0.0643
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0041 0.0455
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0064 0.0158
Brugia malayi brahma associated protein 60 kDa 0.0385 0.0648 0.2391
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0014 0.0014
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0137 0.022 0.334
Onchocerca volvulus Pyruvate kinase homolog 0.0042 0.0056 0.0206
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0034 0.0041 0.0424
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.012
Echinococcus multilocularis 6 phosphofructokinase 0.0091 0.014 0.014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0168 0.0274 0.0274
Leishmania major proteasome beta 5 subunit, putative 0.0042 0.0056 0.1227
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0337 0.0565 0.0565
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0015 0.0037
Echinococcus multilocularis axis inhibition protein axin 0.0017 0.0013 0.0012
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0042 0.0056 0.0438
Schistosoma mansoni pyruvate kinase 0.0042 0.0056 0.0137
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0137 0.022 0.4834
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.002 0.0017 0.0017
Brugia malayi beta-lactamase family protein 0.0034 0.0041 0.0151
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0022 0.0225
Brugia malayi Histone deacetylase family protein 0.0018 0.0014 0.0053
Echinococcus multilocularis pyruvate kinase 0.0042 0.0056 0.0056
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0175 0.0285 0.1052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0027
Echinococcus granulosus expressed protein 0.0011 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0182 0.0298 0.0731
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0088 0.0134 0.0496
Echinococcus multilocularis tissue type plasminogen activator 0.0098 0.0153 0.0153
Echinococcus granulosus metabotropic glutamate receptor 5 0.0854 0.1458 0.1458
Brugia malayi regulator of G-protein signaling egl-10 0.0017 0.0013 0.0046
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0025 0.0025 0.0062
Mycobacterium tuberculosis Probable lipase LipD 0.0034 0.0041 0.043
Schistosoma mansoni importin beta-1 0.0017 0.0012 0.003
Mycobacterium ulcerans beta-lactamase 0.0034 0.0041 0.0424
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0128
Trichomonas vaginalis phosphofructokinase, putative 0.0091 0.014 0.1597
Echinococcus multilocularis zinc finger protein Ran binding 0.0137 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0046
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0085 0.013 0.0479
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0168 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0854 0.1458 0.5378
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0046
Leishmania major 4-coumarate:coa ligase-like protein 0.003 0.0035 0.0764
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0035 0.0044 0.0107
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0042 0.0056 0.1227
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0023 0.0084
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0085 0.0085
Brugia malayi Carboxylesterase family protein 0.0051 0.0071 0.0262
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0012 0.0176
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0042
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0015 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0027 0.0066
Echinococcus granulosus receptor type guanylyl cyclase 0.0088 0.0134 0.0134
Brugia malayi Regulator of G protein signaling domain containing protein 0.0017 0.0013 0.0046
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0027 0.003 0.0659
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0035 0.0361
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Echinococcus granulosus expressed protein 0.0333 0.0559 0.0559
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0043 0.0056 0.0803
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Trypanosoma cruzi phytoene synthase, putative 0.0085 0.013 0.2859
Leishmania major 4-coumarate:coa ligase-like protein 0.003 0.0035 0.0764
Brugia malayi AMP-binding enzyme family protein 0.003 0.0035 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0385 0.0648 0.7419
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0567 0.0962 0.2357
Brugia malayi AMP-binding enzyme family protein 0.003 0.0035 0.0128
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0017 0.0012 0.003
Brugia malayi beta-lactamase 0.0034 0.0041 0.0151
Loa Loa (eye worm) hypothetical protein 0.0308 0.0515 0.1899
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0027
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0008 0.0008
Plasmodium falciparum histone deacetylase, putative 0.0018 0.0014 0.015
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0029 0.0033 0.012
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0005 0.0017
Leishmania major histone deacetylase, putative 0.0018 0.0014 0.0315
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0033 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Loa Loa (eye worm) matrixin family protein 0.0536 0.0909 0.3354
Plasmodium falciparum proteasome subunit beta type-5 0.0042 0.0056 0.0794
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0034 0.0041 0.043
Brugia malayi MH2 domain containing protein 0.0112 0.0177 0.0652
Echinococcus multilocularis glutamate receptor 2 0.0216 0.0356 0.0356
Onchocerca volvulus 0.0018 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0567 0.0962 0.3546
Onchocerca volvulus 0.0151 0.0244 0.09
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0168 0.0274 0.0274
Echinococcus multilocularis chromobox protein 1 0.0022 0.0022 0.0022
Entamoeba histolytica acyl-CoA synthetase, putative 0.003 0.0035 0.2151
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0035 0.0307
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.0014 0.0053
Mycobacterium tuberculosis Conserved protein 0.0034 0.0041 0.043
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0014 0.0007 0.0073
Brugia malayi CXXC zinc finger family protein 0.0019 0.0015 0.0055
Onchocerca volvulus 0.003 0.0035 0.0128
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0008 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.0137 0.022 0.4834
Loa Loa (eye worm) glutaminase 2 0.0515 0.0873 0.3221
Plasmodium vivax histone deacetylase 1, putative 0.0014 0.0007 0.0043
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0008 0.0008
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0007 0.0073
Entamoeba histolytica hypothetical protein 0.0101 0.0157 1
Mycobacterium leprae probable zinc metalloprotease 0.0069 0.0103 0.1422
Loa Loa (eye worm) hypothetical protein 0.0051 0.0071 0.0263
Trypanosoma cruzi squalene synthase, putative 0.0273 0.0454 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0017 0.0013 0.0031
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0025 0.0025 0.0323
Onchocerca volvulus 0.0014 0.0008 0.0029
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0049 0.0068 0.0068
Brugia malayi histone deacetylase 1 (HD1) 0.0014 0.0007 0.0027
Treponema pallidum hypothetical protein 0.0101 0.0157 0.0152
Toxoplasma gondii microneme protein MIC17B 0.0023 0.0022 0.0328
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0015 0.0015
Echinococcus granulosus neuropeptide receptor A26 0.0585 0.0993 0.0993
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0189 0.0464
Echinococcus granulosus axis inhibition protein axin 0.0017 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Echinococcus multilocularis tar DNA binding protein 0.0119 0.0189 0.0189
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0027 0.003 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0041 0.0898
Trichomonas vaginalis glutaminase, putative 0.0515 0.0873 1
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Schistosoma mansoni pyruvate kinase 0.0042 0.0056 0.0137
Brugia malayi Pyruvate kinase, M2 isozyme 0.0042 0.0056 0.0206
Echinococcus multilocularis carboxylesterase 5A 0.0051 0.0071 0.0071
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0085 0.0085
Onchocerca volvulus Matrix metalloproteinase homolog 0.0561 0.0952 0.3509
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0042
Brugia malayi von Willebrand Factor 0.0101 0.0157 0.058
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0013 0.0032
Schistosoma mansoni glutamate receptor AMPA 0.0128 0.0204 0.0501
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0101 0.0157 0.058
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0035 0.0044 0.0107
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0029 0.0033 0.012
Brugia malayi Inositol-1 0.0042 0.0055 0.0204
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Toxoplasma gondii microneme protein MIC4 0.0023 0.0022 0.0328
Schistosoma mansoni rab6-interacting 0.0018 0.0013 0.0033
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0022 0.0328
Brugia malayi Trypsin family protein 0.0567 0.0962 0.3546
Echinococcus multilocularis pyruvate kinase 0.0042 0.0056 0.0056
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0014 0.0315
Onchocerca volvulus 0.1013 0.1733 0.6391
Plasmodium falciparum histone deacetylase 1 0.0014 0.0007 0.0043
Trypanosoma brucei histone deacetylase, putative 0.0018 0.0014 0.0315
Onchocerca volvulus 0.0137 0.022 0.081
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0015 0.0057
Echinococcus multilocularis axis inhibition protein axin 0.0017 0.0013 0.0012
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0014 0.0008 0.0019
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0048 0.0571
Schistosoma mansoni pyruvate kinase 0.0022 0.002 0.005
Leishmania major hypothetical protein, conserved 0.0137 0.022 0.4834
Onchocerca volvulus 0.0014 0.0008 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0015 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0385 0.0648 1
Leishmania major hypothetical protein, conserved 0.0137 0.022 0.4834
Mycobacterium tuberculosis Probable lipase LipE 0.0034 0.0041 0.043
Echinococcus granulosus chromobox protein 1 0.0022 0.0022 0.0022
Echinococcus granulosus nAChR subunit 0.0014 0.0008 0.0008
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0027 0.003 0.0659
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0007 0.0066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0118 0.0186 0.0686
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0022 0.0328
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0015 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0007 0.0073
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.002 0.0017 0.0017
Brugia malayi hypothetical protein 0.0076 0.0114 0.0419
Echinococcus granulosus carbonic anhydrase 0.0029 0.0033 0.0033
Loa Loa (eye worm) histone deacetylase 0.0018 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Echinococcus multilocularis expressed protein 0.0333 0.0559 0.0559
Trypanosoma brucei carbonic anhydrase-like protein 0.0077 0.0117 0.2571
Schistosoma mansoni protein kinase 0.0088 0.0134 0.0329
Echinococcus granulosus glutamate receptor subunit protein glur 0.0047 0.0065 0.0065
Leishmania major hypothetical protein, conserved 0.0085 0.013 0.2859
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0008 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.003 0.0035 0.0361
Onchocerca volvulus 0.0106 0.0165 0.061
Schistosoma mansoni axis inhibition protein axin 0.0017 0.0013 0.0031
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Schistosoma mansoni hypothetical protein 0.0029 0.0033 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0015 0.0057
Loa Loa (eye worm) glutamate receptor 2 0.0128 0.0204 0.0754
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0008 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0189 0.0464
Trypanosoma cruzi WLM domain containing protein, putative 0.0137 0.022 0.4834
Mycobacterium ulcerans hypothetical protein 0.0034 0.0041 0.0424
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0022 0.0082
Mycobacterium leprae Probable pyruvate kinase PykA 0.0042 0.0056 0.0439
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0266 0.0443 0.1632
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0015 0.0015
Onchocerca volvulus Huntingtin homolog 0.0076 0.0114 0.0419
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Echinococcus granulosus GTP binding nuclear protein Ran 0.0013 0.0005 0.0005
Echinococcus multilocularis pyruvate kinase 0.0022 0.002 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0025 0.0025 0.0323
Plasmodium falciparum LCCL domain-containing protein 0.0018 0.0013 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0189 0.0464
Leishmania major histone deacetylase, putative 0.0014 0.0007 0.0164
Echinococcus granulosus histone deacetylase 6 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.008
Echinococcus multilocularis Mastin 0.0567 0.0962 0.0962
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0022 0.0237
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0151
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0014 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Brugia malayi Guanylyl cyclase protein 23 0.0088 0.0134 0.0496
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Onchocerca volvulus 0.0137 0.022 0.081
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0077 0.0117 0.0431
Echinococcus granulosus glutamate receptor 2 0.0168 0.0274 0.0274
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0011 0.0002 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0015 0.0015
Toxoplasma gondii peptidase family M13 protein 0.0069 0.0103 0.1574
Loa Loa (eye worm) hypothetical protein 0.0253 0.042 0.1548
Schistosoma mansoni lipoxygenase 0.0049 0.0068 0.0167
Toxoplasma gondii phosphofructokinase PFKII 0.0025 0.0025 0.0377
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0017 0.0012 0.003
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0106 0.0165 0.061
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0017 0.0013 0.0131
Trichomonas vaginalis pyruvate kinase, putative 0.0042 0.0056 0.0627
Echinococcus granulosus GPCR family 3 C terminal 0.0109 0.0172 0.0172
Onchocerca volvulus 0.0023 0.0022 0.0082
Echinococcus granulosus zinc finger protein Ran binding 0.0137 0.022 0.022
Onchocerca volvulus 0.0059 0.0085 0.0313
Brugia malayi hypothetical protein 0.0102 0.0159 0.0587
Entamoeba histolytica Ran family GTPase 0.0013 0.0005 0.0229
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0013 0.0031
Brugia malayi hypothetical protein 0.0088 0.0134 0.0496
Schistosoma mansoni carbonic anhydrase-related 0.0029 0.0033 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0567 0.0962 0.2357
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Schistosoma mansoni z-protein (S1r protein) 0.0017 0.0013 0.0031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0017 0.0013 0.0048
Trypanosoma brucei pyruvate kinase 1 0.0042 0.0056 0.1228
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0042
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0567 0.0962 0.2357
Leishmania major extracellular receptor, putative 0.0088 0.0134 0.2959
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0151
Echinococcus granulosus tar DNA binding protein 0.0119 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0128
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0013 0.0005 0.0018
Trypanosoma cruzi importin beta-1 subunit, putative 0.0014 0.0007 0.0152
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.004 0.0418
Echinococcus multilocularis neuropeptide s receptor 0.0585 0.0993 0.0993
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0337 0.0565 0.0565
Echinococcus granulosus mitogen activated protein kinase 0.0027 0.003 0.003
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0101 0.0157 0.1791
Schistosoma mansoni metabotropic glutamate receptor 0.0353 0.0593 0.1452
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0013 0.0031
Echinococcus granulosus pyruvate kinase 0.0022 0.002 0.002
Brugia malayi nuclear hormone receptor 0.0019 0.0015 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0035 0.0361
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0015 0.0015
Toxoplasma gondii subtilisin SUB12 0.0023 0.0022 0.0328
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0077 0.0117 0.2571
Loa Loa (eye worm) glutamate receptor 0.0265 0.0441 0.1626
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0034 0.0041 0.043
Onchocerca volvulus 0.0101 0.0157 0.058
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0008 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0091 0.014 0.1597
Trichomonas vaginalis phosphofructokinase, putative 0.0091 0.014 0.1597
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0041 0.0455
Loa Loa (eye worm) 6-phosphofructokinase 0.0091 0.014 0.0518
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0423 0.0714 0.0714
Entamoeba histolytica hypothetical protein 0.0017 0.0013 0.0731
Brugia malayi steroid hormone receptor 0.0019 0.0015 0.0057
Schistosoma mansoni carbonic anhydrase 0.0029 0.0033 0.008
Loa Loa (eye worm) hypothetical protein 0.0137 0.022 0.081
Leishmania major hypothetical protein, conserved 0.0137 0.022 0.4834
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0015 0.0057
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0015 0.0057
Echinococcus granulosus regulator of G protein signaling 3 0.0017 0.0013 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0015 0.0057
Loa Loa (eye worm) matrix metalloproteinase 0.0253 0.042 0.1548
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0124
Echinococcus multilocularis mitogen activated protein kinase 3 0.0027 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0253 0.042 0.1548
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0013 0.0005 0.0103
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0059 0.0085 0.0313
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0611 0.1038 0.3827
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0015 0.0057
Schistosoma mansoni tyrosine kinase 0.0088 0.0134 0.0329
Loa Loa (eye worm) brahma associated protein 0.0385 0.0648 0.2391
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Loa Loa (eye worm) inositol-1 0.0042 0.0055 0.0204
Trypanosoma brucei pyruvate kinase 1, putative 0.0042 0.0056 0.1228
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0013 0.0032
Echinococcus multilocularis glutamate receptor 2 0.0168 0.0274 0.0274
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0055 0.1219
Brugia malayi RNA recognition motif domain containing protein 0.0119 0.0189 0.0698
Plasmodium vivax histone deacetylase 2, putative 0.0018 0.0014 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.0025 0.0025 0.028
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0014 0.0007 0.0073
Schistosoma mansoni hypothetical protein 0.0047 0.0065 0.0159
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0017 0.0013 0.0031
Brugia malayi excitatory GABA receptor EXP-1A 0.0014 0.0008 0.0029
Toxoplasma gondii microneme protein, putative 0.0023 0.0022 0.0328
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0014 0.0008 0.0029
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0041 0.0455
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0766 0.1307 0.3203
Echinococcus multilocularis regulator of G protein signaling 0.0017 0.0013 0.0012
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0055 0.0055
Leishmania major 4-coumarate:coa ligase-like protein 0.003 0.0035 0.0764
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0337 0.0565 0.0565
Onchocerca volvulus Huntingtin homolog 0.0076 0.0114 0.0419
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0013 0.0013
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0168 0.0274 0.0274
Echinococcus multilocularis beta adrenergic receptor kinase 0.0017 0.0013 0.0013
Brugia malayi histone deacetylase 3 (HD3) 0.0014 0.0007 0.0027
Loa Loa (eye worm) peptidase family M13 containing protein 0.0051 0.0072 0.0264
Loa Loa (eye worm) hypothetical protein 0.0137 0.022 0.081
Loa Loa (eye worm) TAR-binding protein 0.0119 0.0189 0.0698
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0272
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0014 0.0014
Loa Loa (eye worm) pyruvate kinase 0.0042 0.0056 0.0206
Schistosoma mansoni hypothetical protein 0.0385 0.0648 0.1589
Brugia malayi Zona pellucida-like domain containing protein 0.0101 0.0157 0.058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0008 0.0029
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0014 0.0035
Onchocerca volvulus 0.0018 0.0013 0.0049
Toxoplasma gondii ran binding protein 0.0137 0.022 0.3376
Onchocerca volvulus 0.0034 0.0041 0.0151
Entamoeba histolytica hypothetical protein 0.0088 0.0134 0.8533
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.0025 0.0025
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0272
Echinococcus multilocularis PHD finger protein rhinoceros 0.0018 0.0014 0.0014
Echinococcus multilocularis tumor protein p63 0.5799 1 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0008 0.0008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0025 0.0025 0.0323
Mycobacterium ulcerans 6-phosphofructokinase 0.0091 0.014 0.146
Leishmania major hypothetical protein, conserved 0.0034 0.0041 0.0898
Brugia malayi Protein kinase domain containing protein 0.0098 0.0153 0.0564
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0182 0.0298 0.11
Loa Loa (eye worm) hypothetical protein 0.0051 0.0072 0.0264
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0567 0.0962 0.3546
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0137 0.022 0.4834
Echinococcus granulosus Polycystic kidney disease protein 0.0018 0.0013 0.0013
Entamoeba histolytica hypothetical protein, conserved 0.0101 0.0157 1
Schistosoma mansoni lipoxygenase 0.0018 0.0013 0.0033
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0308 0.0515 1
Brugia malayi Cache domain containing protein 0.1095 0.1874 0.691
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0014 0.0315
Mycobacterium ulcerans esterase/lipase LipP 0.0034 0.0041 0.0424
Schistosoma mansoni cpg binding protein 0.002 0.0017 0.0041
Schistosoma mansoni glutamate receptor NMDA 0.0216 0.0356 0.0872
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0567 0.0962 0.0962
Echinococcus multilocularis Regulator of G protein signaling 20 0.0017 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0567 0.0962 0.3546
Brugia malayi Trypsin family protein 0.0567 0.0962 0.3546
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0137 0.022 0.081
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.022 0.4834
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0567 0.0962 0.2357
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0025 0.0025 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0015 0.0057
Leishmania major hypothetical protein, conserved 0.0098 0.0153 0.3364
Loa Loa (eye worm) hypothetical protein 0.0137 0.022 0.081
Brugia malayi Latrophilin receptor protein 2 0.002 0.0017 0.0064
Schistosoma mansoni rotamase 0.0011 0.0002 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0015 0.0037
Echinococcus granulosus SWI:SNF matrix associated 0.0385 0.0648 0.0648
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0015 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0015 0.0057
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0385 0.0648 0.0648
Brugia malayi hypothetical protein 0.0018 0.0013 0.0049
Brugia malayi Heterochromatin protein 1 0.0022 0.0022 0.008
Brugia malayi Cation transporter family protein 0.0014 0.0008 0.0029
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0011 0.0001 0.0024
Onchocerca volvulus 0.0019 0.0015 0.0057
Echinococcus granulosus axis inhibition protein axin 0.0017 0.0013 0.0012
Echinococcus multilocularis carbonic anhydrase 0.0029 0.0033 0.0033
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0101 0.0157 0.2372
Schistosoma mansoni neprilysin-2 (M13 family) 0.0035 0.0044 0.0107
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0015 0.0057
Schistosoma mansoni jumonji/arid domain-containing protein 0.0023 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0272
Loa Loa (eye worm) hypothetical protein 0.0076 0.0114 0.0419
Echinococcus multilocularis nmda type glutamate receptor 0.0047 0.0065 0.0065
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0025 0.0025 0.0377
Schistosoma mansoni glutamate receptor NMDA 0.0128 0.0204 0.0501
Echinococcus granulosus histone deacetylase 6 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0099
Brugia malayi Regulator of G protein signaling domain containing protein 0.0017 0.0013 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0041
Brugia malayi PHD-finger family protein 0.0018 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Brugia malayi hypothetical protein 0.0018 0.0013 0.0049
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0043 0.0056 0.0036
Schistosoma mansoni serine-rich repeat protein 0.1277 0.2189 0.5365
Schistosoma mansoni RNA binding protein 0.0137 0.022 0.0538
Schistosoma mansoni ATP-binding cassette transporter 0.0128 0.0204 0.0501
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0015 0.0037
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0017 0.0013 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.00000082252 0.0000030331
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0272
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0041 0.0898
Echinococcus granulosus voltage dependent calcium channel subunit 0.5437 0.9374 0.9374
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0034 0.0041 0.0151
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0015 0.0057
Toxoplasma gondii ABC1 family protein 0.0034 0.0041 0.0614
Echinococcus granulosus histone deacetylase 1 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0046
Onchocerca volvulus Pyruvate kinase homolog 0.0042 0.0056 0.0206
Schistosoma mansoni coup transcription factor 0.0019 0.0015 0.0037
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0042 0.0056 0.0731
Loa Loa (eye worm) phosphofructokinase 0.0091 0.014 0.0518
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0008 0.0029
Echinococcus granulosus transmembrane protease serine 3 0.0567 0.0962 0.0962
Brugia malayi Matrixin family protein 0.0536 0.0909 0.3354
Onchocerca volvulus Matrilysin homolog 0.0561 0.0952 0.3509
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0015 0.0057
Brugia malayi Histone deacetylase 1 0.0014 0.0007 0.0027
Brugia malayi beta-lactamase family protein 0.0034 0.0041 0.0151
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0042 0.0056 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Entamoeba histolytica phosphofructokinase, putative 0.0091 0.014 0.8916
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0027 0.0027
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0033 0.004 0.0417
Schistosoma mansoni 6-phosphofructokinase 0.0091 0.014 0.0344
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0013 0.0031
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0119 0.0189 0.0698
Plasmodium vivax proteasome subunit beta type-5, putative 0.0042 0.0056 0.0794
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0027 0.003 0.0659
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0027 0.003 0.0659
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0042 0.0056 0.1227
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0043 0.0056 0.0554
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0008 0.0008
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0015 0.0037
Echinococcus multilocularis lysine specific demethylase 5A 0.0022 0.0021 0.0021
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0008 0.0008
Echinococcus multilocularis histone deacetylase 3 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.008
Schistosoma mansoni neprilysin 0.0018 0.0014 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0118 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0043 0.0057 0.0212
Brugia malayi latrophilin 2 splice variant baaae 0.0043 0.0057 0.0212
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.00000082252 0.0000030331
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Onchocerca volvulus 0.0014 0.0008 0.0029
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0011 0.0001 0.0024
Onchocerca volvulus 0.0101 0.0157 0.058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0015 0.0057
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0043 0.0056 0.0854
Echinococcus multilocularis Squalene phytoene synthase 0.0085 0.013 0.013
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0385 0.0648 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Echinococcus multilocularis pyruvate kinase 0.0033 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0206
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0118 0.0186 0.0186
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0854 0.1458 0.1458
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0015 0.0015
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0567 0.0962 0.0962
Schistosoma mansoni aldehyde dehydrogenase 0.0033 0.004 0.0098
Loa Loa (eye worm) RGC/RGC protein kinase 0.0088 0.0134 0.0496
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0022 0.0237
Echinococcus multilocularis carbonic anhydrase 0.0029 0.0033 0.0033
Loa Loa (eye worm) carboxylesterase 0.0051 0.0071 0.0263
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0589 0.1 0.1
Mycobacterium leprae Probable lipase LipE 0.0034 0.0041 0.0127
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0014 0.0008 0.0029
Chlamydia trachomatis SWIB complex protein 0.0385 0.0648 1
Onchocerca volvulus 0.0101 0.0157 0.058
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Schistosoma mansoni carbonic anhydrase-related 0.0029 0.0033 0.008
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.5035 0.868 1
Echinococcus granulosus carbonic anhydrase II 0.0077 0.0117 0.0117
Echinococcus multilocularis voltage dependent calcium channel subunit 0.2473 0.4254 0.4254
Giardia lamblia Pyruvate kinase 0.0042 0.0056 1
Leishmania major histone deacetylase, putative 0.0014 0.0007 0.0164
Onchocerca volvulus 0.0023 0.0022 0.0082
Brugia malayi hypothetical protein 0.0017 0.0013 0.0046
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0013 0.0005 0.0055
Schistosoma mansoni hypothetical protein 0.0283 0.0473 0.1158
Echinococcus granulosus carbonic anhydrase 0.0029 0.0033 0.0033
Loa Loa (eye worm) LGC-31 protein 0.0014 0.0008 0.0029
Leishmania major importin beta-1 subunit, putative 0.0014 0.0007 0.0152
Echinococcus granulosus L aminoadipate semialdehyde 0.0151 0.0244 0.0244
Leishmania major histone deacetylase, putative 0.0018 0.0014 0.0315
Loa Loa (eye worm) doublecortin family protein 0.0018 0.0013 0.0049
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0001 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0013 0.0131
Loa Loa (eye worm) matrixin family protein 0.0561 0.0952 0.3509
Loa Loa (eye worm) RGC/RGC protein kinase 0.0088 0.0134 0.0496
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Trichomonas vaginalis phosphofructokinase, putative 0.0025 0.0025 0.028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0015 0.0057
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0055 0.0622
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0042 0.0056 0.3498
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0063 0.0092 0.0339
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0008 0.0019
Echinococcus granulosus beta LACTamase domain containing family member 0.0034 0.0041 0.0041
Echinococcus multilocularis regulator of G protein signaling 3 0.0017 0.0013 0.0012
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0844 0.1441 0.1441
Echinococcus multilocularis nAChR subunit 0.0014 0.0008 0.0008
Onchocerca volvulus 0.0023 0.0022 0.0082
Loa Loa (eye worm) hypothetical protein 0.0567 0.0962 0.3546
Loa Loa (eye worm) zinc metallopeptidase 4 0.0017 0.0012 0.0045
Echinococcus granulosus carbonic anhydrase 0.0029 0.0033 0.0033
Echinococcus granulosus pyruvate kinase 0.0022 0.002 0.002
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0088 0.0134 0.0496
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0008 0.0008
Loa Loa (eye worm) heterochromatin protein 1 0.0022 0.0022 0.008
Mycobacterium tuberculosis Probable hydrolase 0.0034 0.0041 0.043
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.1196 0.2048 0.502
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0015 0.0057
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0025 0.0025 0.4071
Leishmania major hypothetical protein, conserved 0.0137 0.022 0.4834
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0011 0.0002 0.0006
Brugia malayi Cation transporter family protein 0.0014 0.0008 0.0029
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0013 0.0005 0.0017
Toxoplasma gondii hypothetical protein 0.0023 0.0022 0.0328
Toxoplasma gondii 6-phosphofructokinase 0.0025 0.0025 0.0377
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0029 0.0033 0.012
Toxoplasma gondii microneme protein MIC2 0.0101 0.0157 0.2414
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0385 0.0648 0.0648
Echinococcus multilocularis mitogen activated protein kinase 0.0027 0.003 0.003
Mycobacterium ulcerans pyruvate kinase 0.0042 0.0056 0.058
Loa Loa (eye worm) hypothetical protein 0.0106 0.0165 0.061
Echinococcus multilocularis histone deacetylase 0.0018 0.0014 0.0014
Echinococcus granulosus snurportin 1 0.0182 0.0298 0.0298
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0055 0.0838
Brugia malayi Matrixin family protein 0.0253 0.042 0.1548
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0014 0.0006 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0015 0.0015
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0007 0.0066
Schistosoma mansoni zinc finger protein 0.0137 0.022 0.0538
Schistosoma mansoni endothelin-converting enzyme-related 0.0017 0.0012 0.003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0151
Echinococcus granulosus mitogen activated protein kinase 3 0.0027 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0013 0.0131
Onchocerca volvulus 0.0567 0.0962 0.3546
Brugia malayi Trypsin-like protease protein 5 0.0567 0.0962 0.3546
Plasmodium vivax hypothetical protein, conserved 0.0101 0.0157 0.2372
Echinococcus multilocularis SWI:SNF matrix associated 0.0385 0.0648 0.0648
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0014 0.0008 0.0019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0027 0.0027
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0214 0.0353 0.6725
Onchocerca volvulus 0.0567 0.0962 0.3546
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0008 0.0008
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0014 0.0008 0.0008
Leishmania major squalene synthase, putative 0.0273 0.0454 1
Loa Loa (eye worm) hypothetical protein 0.158 0.2712 1
Schistosoma mansoni chromobox protein 0.0022 0.0022 0.0053
Plasmodium falciparum thrombospondin-related anonymous protein 0.0101 0.0157 0.2372
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0014 0.0008 0.0029
Echinococcus multilocularis glycoprotein Antigen 5 0.0567 0.0962 0.0962
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0022 0.0022 0.0043
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Echinococcus granulosus tyrosine kinase 0.0088 0.0134 0.0134
Onchocerca volvulus 0.0023 0.0022 0.0082
Echinococcus granulosus 6 phosphofructokinase 0.0091 0.014 0.014
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0015 0.0015
Loa Loa (eye worm) histone deacetylase 3 0.0014 0.0007 0.0027
Brugia malayi peptidase family M13 containing protein 0.0017 0.0012 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0015 0.0057
Onchocerca volvulus Matrilysin homolog 0.0253 0.042 0.1548
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0043 0.0056 0.0586
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Brugia malayi Hemopexin family protein 0.0283 0.0473 0.1743
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0013 0.0012
Echinococcus granulosus chromobox protein 1 0.0022 0.0022 0.0022
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Trypanosoma cruzi pyruvate kinase 2, putative 0.0042 0.0056 0.1228
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0013 0.0005 0.0103
Echinococcus granulosus RUN 0.0018 0.0013 0.0013
Toxoplasma gondii microneme protein MIC17C 0.0023 0.0022 0.0328
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0013 0.0005 0.0017
Onchocerca volvulus 0.158 0.2712 1
Brugia malayi nuclear receptor NHR-88 0.0019 0.0015 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0013 0.0131
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0156
Plasmodium vivax acyl-CoA synthetase, putative 0.0022 0.0022 0.0263
Brugia malayi Receptor family ligand binding region containing protein 0.0088 0.0134 0.0496
Echinococcus multilocularis beta LACTamase domain containing family member 0.0034 0.0041 0.0041
Giardia lamblia Kinase, CMGC MAPK 0.0027 0.003 0.4942
Schistosoma mansoni TRABID protein (C64 family) 0.0137 0.022 0.0538
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0001 0.0024
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Mycobacterium ulcerans proteasome PrcB 0.0042 0.0056 0.058
Echinococcus multilocularis enteropeptidase 0.0567 0.0962 0.0962
Mycobacterium ulcerans phytoene synthase, CrtB 0.0085 0.013 0.135
Brugia malayi Bromodomain containing protein 0.0018 0.0014 0.0053
Mycobacterium ulcerans hypothetical protein 0.003 0.0035 0.0361
Schistosoma mansoni aldehyde dehydrogenase 0.0033 0.004 0.0098
Plasmodium falciparum acyl-CoA synthetase 0.0022 0.0022 0.0263
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0046
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0077 0.0117 0.0286
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Onchocerca volvulus 0.0567 0.0962 0.3546
Brugia malayi Trypsin family protein 0.0567 0.0962 0.3546
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0027 0.003 0.0659
Echinococcus multilocularis acetylcholinesterase 0.0051 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0015 0.0057
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0308 0.0515 0.1899
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0272
Brugia malayi hypothetical protein 0.0017 0.0013 0.0046
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0385 0.0648 1
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0041 0.0455
Schistosoma mansoni histone deacetylase 0.0014 0.0007 0.0018
Echinococcus granulosus glutamate NMDA receptor subunit 0.0128 0.0204 0.0204
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0337 0.0565 0.0565
Plasmodium vivax 6-phosphofructokinase, putative 0.0025 0.0025 0.0323
Mycobacterium leprae PROBABLE HYDROLASE 0.0308 0.0515 1
Echinococcus granulosus carboxylesterase 5A 0.0051 0.0071 0.0071
Brugia malayi Glutamate receptor 2 precursor 0.0128 0.0204 0.0753
Loa Loa (eye worm) hypothetical protein 0.0137 0.022 0.081
Echinococcus multilocularis SWI:SNF matrix associated 0.0385 0.0648 0.0648
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.002 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0014 0.0007 0.037
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0013 0.0005 0.0017
Brugia malayi Matrixin family protein 0.0253 0.042 0.1548
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.022 0.4834
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0055 0.0576
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0014 0.0007 0.0073
Schistosoma mansoni tyrosine kinase 0.0088 0.0134 0.0329
Echinococcus multilocularis importin subunit beta 1 0.0017 0.0012 0.0012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0027 0.003 0.0446
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0101 0.0157 0.2372
Toxoplasma gondii aldehyde dehydrogenase 0.0033 0.004 0.0604
Trypanosoma brucei histone deacetylase 4 0.0018 0.0014 0.0315
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0014 0.0008 0.0008
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0091 0.014 0.3091
Brugia malayi RNA, U transporter 1 0.0049 0.0067 0.0247
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0069 0.0103 0.038
Onchocerca volvulus 0.0023 0.0022 0.0082
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0055 0.1219
Loa Loa (eye worm) hypothetical protein 0.0051 0.0071 0.0263
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0077 0.0117 0.0431
Echinococcus multilocularis L aminoadipate semialdehyde 0.0151 0.0244 0.0244
Mycobacterium ulcerans glutaminase 0.0515 0.0873 0.9082
Onchocerca volvulus 0.0199 0.0327 0.1205
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0013 0.0013
Leishmania major GTP-binding protein, putative 0.0013 0.0005 0.0103
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0017 0.0013 0.0012
Loa Loa (eye worm) 6-phosphofructokinase 0.0091 0.014 0.0518
Onchocerca volvulus 0.0019 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0289 0.0482 0.1779
Echinococcus granulosus enteropeptidase 0.0567 0.0962 0.0962
Brugia malayi Calcitonin receptor-like protein seb-1 0.0063 0.0092 0.0339
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0049
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0216 0.0356 0.0356
Echinococcus multilocularis peregrin 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Brugia malayi Kringle domain containing protein 0.0098 0.0153 0.0564
Brugia malayi jmjC domain containing protein 0.0059 0.0085 0.0315
Schistosoma mansoni glutaminase 0.0515 0.0873 0.2141
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.003 0.0331
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0137 0.022 0.022
Entamoeba histolytica elongation factor-2 kinase, putative 0.0101 0.0157 1
Echinococcus granulosus ring and YY1 binding protein 0.0137 0.022 0.022
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0137 0.022 0.4834
Echinococcus multilocularis GPCR, family 2 0.002 0.0017 0.0017
Trichomonas vaginalis set domain proteins, putative 0.0199 0.0327 0.3734
Leishmania major phosphopantetheinyl transferase-like protein 0.0043 0.0056 0.1241
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0003 0.0007
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0137 0.022 0.022
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0063 0.0092 0.0339
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0046
Brugia malayi Pre-SET motif family protein 0.0025 0.0027 0.0099
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0042 0.0056 0.0732
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0013 0.0031
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0017 0.0013 0.0012
Onchocerca volvulus 0.0023 0.0022 0.0082
Schistosoma mansoni hypothetical protein 0.0567 0.0962 0.2357
Loa Loa (eye worm) hypothetical protein 0.0253 0.042 0.1548
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0033 0.0081
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0035
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0056 0.0626
Loa Loa (eye worm) hypothetical protein 0.0051 0.0072 0.0264
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0015 0.0037
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0029 0.0033 0.012
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0034 0.0041 0.043
Echinococcus multilocularis NMDA receptor 0.0168 0.0274 0.0274
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Loa Loa (eye worm) hypothetical protein 0.0098 0.0153 0.0564
Trichomonas vaginalis phosphofructokinase, putative 0.0025 0.0025 0.028
Entamoeba histolytica hypothetical protein 0.0017 0.0013 0.0731
Echinococcus granulosus acetylcholinesterase 0.0051 0.0071 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0023 0.0023 0.0055
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Brugia malayi brahma associated protein 60 kDa 0.0385 0.0648 0.2391
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0101 0.0157 0.2372
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0006 0.006
Trypanosoma cruzi pyruvate kinase 2, putative 0.0042 0.0056 0.1228
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0014 0.0203
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.2372 0.408 1
Trichomonas vaginalis phosphofructokinase, putative 0.0025 0.0025 0.028
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0055 0.1219
Echinococcus multilocularis pyruvate kinase 0.0022 0.002 0.002
Brugia malayi Proteasome A-type and B-type family protein 0.0042 0.0056 0.0206
Schistosoma mansoni fusion 0.0137 0.022 0.0538
Echinococcus granulosus histone deacetylase 7 0.0018 0.0014 0.0014
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0029 0.0033 0.012
Mycobacterium tuberculosis Conserved protein 0.0034 0.0041 0.043
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0109 0.0172 0.0634
Loa Loa (eye worm) hypothetical protein 0.0051 0.0072 0.0264
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0046
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0014 0.0008 0.0008
Brugia malayi Histone deacetylase family protein 0.0018 0.0014 0.0053
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0015 0.0057
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0091 0.014 0.0133
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0069 0.0103 0.1685
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0013 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0013 0.0013
Echinococcus granulosus atrial natriuretic peptide receptor 0.0088 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0069 0.0103 0.038
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Mycobacterium ulcerans zinc metalloprotease 0.0069 0.0103 0.1071
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0017 0.0013 0.0031
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0013 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.003 0.0073
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0048 0.0175
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0567 0.0962 0.0962
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0006 0.006
Echinococcus multilocularis nmda type glutamate receptor 0.0088 0.0134 0.0134
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.158 0.2712 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0118 0.0186 0.0456
Loa Loa (eye worm) histone deacetylase 7A 0.0018 0.0014 0.0053
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0101 0.0157 0.2372
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0013 0.0012
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0137 0.022 0.3376
Echinococcus granulosus metabotropic glutamate receptor 2 0.0589 0.1 0.1
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0137 0.022 0.4834
Echinococcus multilocularis voltage dependent calcium channel subunit 0.5437 0.9374 0.9374
Onchocerca volvulus 0.0023 0.0022 0.0082
Schistosoma mansoni loxhd1 0.0018 0.0013 0.0033
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0567 0.0962 0.2357
Plasmodium falciparum pyruvate kinase 0.0042 0.0056 0.0794
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0015 0.0015
Onchocerca volvulus 0.0088 0.0134 0.0496
Schistosoma mansoni histone deacetylase 0.0014 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0022 0.0328
Echinococcus multilocularis endothelin converting enzyme 1 0.0069 0.0103 0.0103
Echinococcus multilocularis jumonji domain containing protein 0.0025 0.0027 0.0026
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0101 0.0157 0.2414
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0101 0.0157 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.022 0.4834
Echinococcus granulosus nmda type glutamate receptor 0.0088 0.0134 0.0134
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0035 0.0044 0.0107
Entamoeba histolytica phosphofructokinase, putative 0.0091 0.014 0.8916
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0151
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.003 0.0331
Echinococcus multilocularis dnaJ subfamily B 0.0265 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0197 0.0323 0.1193
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Brugia malayi Doublecortin family protein 0.0018 0.0013 0.0049
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0007 0.0073
Loa Loa (eye worm) CYP4Cod1 0.001 0.00000082252 0.0000030331
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0033 0.004 0.004
Schistosoma mansoni nAChR subunit 0.0014 0.0008 0.0019
Toxoplasma gondii pyruvate kinase PyKII 0.0022 0.002 0.0297
Brugia malayi hypothetical protein 0.0289 0.0482 0.1779
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0069 0.0103 0.0252
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0056 0.1241
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0042 0.0056 0.9992
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0015 0.0015
Schistosoma mansoni inositol monophosphatase 0.0042 0.0055 0.0136
Trypanosoma cruzi histone deacetylase 1, putative 0.0014 0.0007 0.0164
Loa Loa (eye worm) beta-lactamase 0.0034 0.0041 0.0151
Echinococcus granulosus dnaJ subfamily B 0.0265 0.044 0.044
Echinococcus granulosus importin subunit beta 1 0.0017 0.0012 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0008 0.0029
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.158 0.2712 0.6647
Onchocerca volvulus Pyruvate kinase homolog 0.0042 0.0056 0.0206
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Leishmania major pyruvate kinase 0.0042 0.0056 0.1228
Echinococcus multilocularis pyruvate kinase 0.0022 0.002 0.002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0013 0.0005 0.0103
Onchocerca volvulus 0.0014 0.0008 0.0029
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0137 0.022 0.081
Loa Loa (eye worm) hypothetical protein 0.0101 0.0157 0.058
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0091 0.014 0.3091
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0055 0.0622
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0014 0.0315
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0041 0.0455
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0015 0.0037
Brugia malayi chromobox protein homolog 3 0.0013 0.0005 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0015 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.0153 0.3364
Echinococcus granulosus glycoprotein Antigen 5 0.0567 0.0962 0.0962
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0077 0.0117 0.2571
Onchocerca volvulus 0.0023 0.0022 0.0082
Entamoeba histolytica histone deacetylase, putative 0.0014 0.0007 0.0405
Trypanosoma brucei squalene synthase, putative 0.0273 0.0454 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0567 0.0962 0.2357
Brugia malayi TAR-binding protein 0.0119 0.0189 0.0698
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0043 0.0056 0.0586
Echinococcus multilocularis survival motor neuron protein 1 0.0289 0.0482 0.0482
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0015 0.0015
Brugia malayi hypothetical protein 0.0101 0.0157 0.058
Trypanosoma cruzi extracellular receptor, putative 0.0088 0.0134 0.2959
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0014 0.0008 0.0008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0015 0.0057
Mycobacterium tuberculosis Conserved protein 0.0034 0.0041 0.043
Brugia malayi Peptidase family M13 containing protein 0.0069 0.0103 0.038
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0025 0.0025 0.1561
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0844 0.1441 0.1441
Echinococcus multilocularis ring and YY1 binding protein 0.0137 0.022 0.022
Plasmodium falciparum pyruvate kinase 2 0.0022 0.002 0.0243
Schistosoma mansoni carbonic anhydrase-related 0.0029 0.0033 0.008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Trypanosoma brucei importin beta-1 subunit, putative 0.0017 0.0012 0.0275
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0077 0.0117 0.0286
Echinococcus granulosus proteasome prosome macropain 0.0042 0.0056 0.0056
Mycobacterium ulcerans hydrolase 0.0308 0.0515 0.5354
Plasmodium vivax importin-beta 2, putative 0.0017 0.0012 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0015 0.0057
Echinococcus multilocularis carbonic anhydrase II 0.0077 0.0117 0.0117
Echinococcus granulosus Mastin 0.0567 0.0962 0.0962
Echinococcus multilocularis histone deacetylase 7 0.0018 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0029 0.0033 0.0487
Loa Loa (eye worm) CXXC zinc finger family protein 0.0019 0.0015 0.0055
Brugia malayi Matrixin family protein 0.0253 0.042 0.1548
Loa Loa (eye worm) hypothetical protein 0.0051 0.0072 0.0264
Trichomonas vaginalis phosphofructokinase, putative 0.0025 0.0025 0.028
Onchocerca volvulus 0.0137 0.022 0.081
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Trypanosoma cruzi histone deacetylase 1, putative 0.0014 0.0007 0.0164
Loa Loa (eye worm) glutamate receptor 1 0.0128 0.0204 0.0754
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0014 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0059 0.0085 0.0208
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0055 0.0055
Onchocerca volvulus 0.0088 0.0134 0.0496
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0085 0.013 0.2228
Loa Loa (eye worm) hypothetical protein 0.0151 0.0244 0.09
Schistosoma mansoni hypothetical protein 0.0101 0.0157 0.0386
Loa Loa (eye worm) hypothetical protein 0.0137 0.022 0.081
Plasmodium vivax SET domain protein, putative 0.0025 0.0027 0.0345
Giardia lamblia Pyruvate kinase 0.0022 0.002 0.3064
Onchocerca volvulus 0.0023 0.0022 0.0082
Onchocerca volvulus 0.0014 0.0008 0.0029
Brugia malayi AMP-binding enzyme family protein 0.003 0.0035 0.0128
Schistosoma mansoni chromobox protein 0.0022 0.0022 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0015 0.0015
Plasmodium falciparum cysteine repeat modular protein 1 0.0098 0.0153 0.2302
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0057
Echinococcus multilocularis GPCR, family 3, C terminal 0.0109 0.0172 0.0172
Onchocerca volvulus 0.0567 0.0962 0.3546
Plasmodium falciparum histone deacetylase 2 0.0018 0.0014 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.0091 0.014 0.1597
Loa Loa (eye worm) hypothetical protein 0.0069 0.0103 0.038
Plasmodium vivax thrombospondin-related anonymous protein 0.0101 0.0157 0.2372
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0014 0.0008 0.0008
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0137 0.022 0.022
Echinococcus granulosus neuropeptide s receptor 0.0585 0.0993 0.0993
Onchocerca volvulus 0.0385 0.0648 0.2391
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0046
Echinococcus granulosus jumonji domain containing protein 0.0025 0.0027 0.0026
Plasmodium vivax histone deacetylase, putative 0.0018 0.0014 0.015
Schistosoma mansoni survival motor neuron protein 0.0059 0.0085 0.0208
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0007 0.0073
Echinococcus multilocularis transmembrane protease serine 3 0.0567 0.0962 0.0962
Schistosoma mansoni rab6-interacting 0.0018 0.0013 0.0033
Chlamydia trachomatis DNA topoisomerase I 0.0385 0.0648 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0137 0.022 0.081
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0055 0.0622
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0385 0.0648 1
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Loa Loa (eye worm) PXA domain-containing protein 0.0017 0.0013 0.0046
Echinococcus multilocularis tyrosine kinase 0.0088 0.0134 0.0134
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0022 0.0082
Onchocerca volvulus 0.0034 0.0041 0.0151
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.003 0.0035 0.0361
Loa Loa (eye worm) RGC/RGC protein kinase 0.0088 0.0134 0.0496
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0018 0.0014 0.0035
Trichomonas vaginalis rotamase, putative 0.0011 0.0002 0.0005
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0151 0.0244 0.0598
Loa Loa (eye worm) glutaminase 0.0515 0.0873 0.3221
Brugia malayi Metabotropic glutamate receptor precursor. 0.0698 0.1189 0.4386
Toxoplasma gondii histone deacetylase HDAC2 0.0014 0.0007 0.0098
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0014 0.0008 0.0029
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0022 0.0082
Brugia malayi Pyruvate kinase, muscle isozyme 0.0042 0.0056 0.0206
Loa Loa (eye worm) transcription factor SMAD2 0.0112 0.0177 0.0652
Echinococcus multilocularis proteasome (prosome, macropain) 0.0042 0.0056 0.0056
Schistosoma mansoni glutamate receptor kainate 0.0249 0.0413 0.1013
Echinococcus granulosus histone deacetylase 6 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0029
Trichomonas vaginalis esterase, putative 0.0034 0.0041 0.0455
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.004 0.0418
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0027 0.003 0.0659
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Loa Loa (eye worm) RGS-3 protein 0.0017 0.0013 0.0046
Brugia malayi PAN domain containing protein 0.0023 0.0022 0.0082
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0022 0.0082
Echinococcus granulosus beta-adrenergic receptor kinase 0.0017 0.0013 0.0013
Echinococcus multilocularis receptor type guanylyl cyclase 0.0088 0.0134 0.0134
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0041 0.0562
Echinococcus granulosus cpg binding protein 0.002 0.0017 0.0017
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0496
Echinococcus granulosus collagen alpha 1VII chain 0.0101 0.0157 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0013 0.0131
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0151
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0042 0.0056 0.0206
Schistosoma mansoni ran 0.0013 0.0005 0.0011
Brugia malayi von Willebrand factor type A domain containing protein 0.0101 0.0157 0.058
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0029 0.0033 0.012
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0088 0.0134 0.0134
Brugia malayi RNA binding protein 0.0119 0.0189 0.0698
Brugia malayi Receptor family ligand binding region containing protein 0.0197 0.0323 0.1193
Echinococcus granulosus pyruvate kinase 0.0042 0.0056 0.0056
Loa Loa (eye worm) CUTiclin-Like family member 0.0101 0.0157 0.058
Echinococcus granulosus PHD finger protein rhinoceros 0.0018 0.0014 0.0014
Echinococcus multilocularis expressed protein 0.0011 0.0002 0.0001

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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