Detailed information for compound 2077552

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 542.472 | Formula: C22H28F6N4O5
  • H donors: 2 H acceptors: 6 LogP: 1.04 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(COCc1cncc2c1CCN(C2)Cc1cnn(c1)C)C
  • InChi: 1S/C18H26N4O.2C2HF3O2/c1-14(2)12-23-13-17-8-19-7-16-11-22(5-4-18(16)17)10-15-6-20-21(3)9-15;2*3-2(4,5)1(6)7/h6-9,14H,4-5,10-13H2,1-3H3;2*(H,6,7)
  • InChiKey: ALDQKVOPDPHSLL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0049 0.0049
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0021 0.0064 0.0064
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.1175 0.646
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0157 0.159 0.159
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0486 0.0486
Trichomonas vaginalis D-aminoacylase, putative 0.0028 0.0135 0.0168
Onchocerca volvulus 0.0037 0.0237 0.0218
Echinococcus granulosus dna polymerase eta 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0426 0.4628 0.4628
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0019 0.009
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0172 0.176 0.2559
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0237 0.0298
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0039 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0019 0.009
Onchocerca volvulus 0.0172 0.176 0.2174
Leishmania major ion transport protein-like protein 0.0037 0.0237 0.3757
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0299 0.8406
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0008 0.0222
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0019 0.0043
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0039 0.0039
Echinococcus granulosus twik family of potassium channels 0.0037 0.0237 0.0237
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0172 0.176 0.176
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Brugia malayi Thioredoxin reductase 0.0047 0.0356 0.0518
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0003 0.0005
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0037 0.0237 0.0344
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0039
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0039 0.0039
Echinococcus granulosus acetylcholinesterase 0.0055 0.0446 0.0446
Brugia malayi intermediate filament protein 0.0022 0.0067 0.0098
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0039 0.0057
Brugia malayi glutathione reductase 0.0047 0.0356 0.0518
Echinococcus multilocularis twik family of potassium channels 0.0037 0.0237 0.0237
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0835 0.0835
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Echinococcus granulosus lamin 0.0022 0.0067 0.0067
Echinococcus granulosus lamin dm0 0.0022 0.0067 0.0067
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0299 0.1505
Brugia malayi Cytochrome P450 family protein 0.0038 0.0247 0.036
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0093 0.0873 0.2311
Echinococcus multilocularis neutral alpha glucosidase AB 0.0027 0.0129 0.0129
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0037 0.0237 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0426 0.4628 0.4628
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0019 0.009
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0003 0.0005
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0122 0.1202 0.1202
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0019 0.0043
Echinococcus multilocularis lysosomal alpha glucosidase 0.0122 0.1202 0.1202
Echinococcus multilocularis calcium activated potassium channel variant 0.0037 0.0237 0.0237
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0079 0.0717 0.1042
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0008 0.0222
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0356 0.4267
Schistosoma mansoni neurotransmitter gated ion channel 0.0092 0.0866 0.0866
Brugia malayi Glycosyl hydrolases family 31 protein 0.0122 0.1202 0.1748
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Echinococcus granulosus nAChR subunit 0.0092 0.0866 0.0866
Echinococcus multilocularis lamin 0.0022 0.0067 0.0067
Echinococcus multilocularis potassium channel subfamily K 8 0.0037 0.0237 0.0237
Onchocerca volvulus 0.0037 0.0237 0.0218
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0247 0.0247
Brugia malayi hypothetical protein 0.0079 0.0717 0.1042
Loa Loa (eye worm) TWK-28 protein 0.0037 0.0237 0.0237
Echinococcus multilocularis twik family of potassium channels 0.0037 0.0237 0.0237
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0079 0.0717 0.1042
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0037 0.0237 0.3757
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0309
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0129 0.0161
Schistosoma mansoni lipoxygenase 0.0058 0.0482 0.0482
Trichomonas vaginalis D-aminoacylase, putative 0.0028 0.0135 0.0168
Trypanosoma cruzi DNA polymerase eta, putative 0.0016 0.0003 0.005
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0079 0.0717 0.0717
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0129 0.064
Trypanosoma brucei trypanothione reductase 0.0047 0.0356 0.5654
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0037 0.0237 0.3757
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.3503 0.3503
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0019 0.0043
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0037 0.0237 0.0344
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0196 0.0196
Loa Loa (eye worm) ACC-1 protein 0.0172 0.176 0.176
Echinococcus multilocularis acetylcholinesterase 0.0055 0.0446 0.0446
Brugia malayi hypothetical protein 0.0079 0.0717 0.1042
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0486 0.0486
Brugia malayi jmjC domain containing protein 0.0059 0.0486 0.0707
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0016 0.0003 0.0003
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0172 0.176 0.176
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0129 0.205
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0417 0.4524 0.4524
Schistosoma mansoni acetylcholine receptor subunit beta 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0072 0.063 0.063
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0039 0.0057
Echinococcus multilocularis dna polymerase kappa 0.0016 0.0003 0.0003
Onchocerca volvulus 0.0172 0.176 0.2174
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0037 0.0237 0.0344
Onchocerca volvulus 0.0426 0.4628 0.5858
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0326 0.3503 0.3503
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0064 0.1022
Onchocerca volvulus 0.0037 0.0237 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0046
Giardia lamblia Hypothetical protein 0.0037 0.0237 0.1187
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.019 0.1965 0.9968
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0083 0.076 0.4172
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.063 0.063
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0039 0.0039
Brugia malayi hypothetical protein 0.0079 0.0717 0.1042
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0046
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0237 0.0298
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Leishmania major trypanothione reductase 0.0047 0.0356 0.5654
Trichomonas vaginalis glutaminase, putative 0.0349 0.3765 0.4793
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0172 0.176 0.176
Mycobacterium tuberculosis Probable hydrolase 0.0028 0.0135 0.0728
Plasmodium falciparum thioredoxin reductase 0.0016 0.0008 0.0222
Onchocerca volvulus 0.0172 0.176 0.2174
Trypanosoma cruzi polo-like protein kinase, putative 0.0072 0.063 1
Brugia malayi Stress-activated protein kinase jnk-1 0.0326 0.3503 0.5094
Giardia lamblia Fructose-bisphosphate aldolase 0.019 0.1972 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis nAChR subunit 0.0172 0.176 0.176
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0129 0.0161
Schistosoma mansoni kinase 0.0037 0.0237 0.0237
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0019 0.0043
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0079 0.0717 0.1042
Giardia lamblia Kinase, PLK 0.0072 0.063 0.3185
Echinococcus multilocularis microtubule associated protein 2 0.045 0.4896 0.4896
Trypanosoma brucei DNA polymerase eta, putative 0.0016 0.0003 0.005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0008 0.0126
Onchocerca volvulus 0.0079 0.0717 0.0834
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Toxoplasma gondii transporter, cation channel family protein 0.0033 0.0196 0.2351
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.154 0.154
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0039 0.0039
Brugia malayi cytochrome P450 0.0017 0.0019 0.0028
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0247 0.0247
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.0003 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.0417 0.4524 0.4524
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0003 0.005
Loa Loa (eye worm) hypothetical protein 0.0055 0.0446 0.0446
Mycobacterium ulcerans lipase LipD 0.0028 0.0135 0.0351
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0019 0.009
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0003 0.005
Loa Loa (eye worm) acetyltransferase 0.0157 0.159 0.159
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0247 0.3926
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Entamoeba histolytica hypothetical protein 0.0019 0.0039 0.0184
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Brugia malayi Carboxylesterase family protein 0.0055 0.0446 0.0648
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0027 0.0129 0.1547
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0135
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0049 0.0049
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.009 0.0835 0.0835
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0172 0.176 0.176
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0835 0.0835
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0037 0.0237 0.3757
Trypanosoma brucei membrane transporter protein, putative 0.0021 0.0064 0.1022
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0039
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0479 0.5232 0.5232
Trypanosoma brucei membrane transporter protein, putative 0.0021 0.0064 0.1022
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0039 0.0039
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0016 0.0003 0.0003
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0072 0.063 0.063
Brugia malayi acetyltransferase, GNAT family protein 0.0157 0.159 0.2312
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0019 0.0309
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0129 0.0161
Echinococcus granulosus intermediate filament protein 0.0022 0.0067 0.0067
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0008 0.5
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0019 0.009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0446 0.0446
Schistosoma mansoni neurotransmitter gated ion channel 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Toxoplasma gondii ion channel protein 0.0037 0.0237 0.2835
Onchocerca volvulus 0.0037 0.0237 0.0218
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0028 0.0135 0.0197
Onchocerca volvulus 0.0028 0.0135 0.0087
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0037 0.0237 0.0344
Onchocerca volvulus 0.0037 0.0237 0.0218
Echinococcus multilocularis glycine receptor subunit beta 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0299 0.1505
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0019 0.0043
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0495 0.5411 0.5411
Trypanosoma brucei MATE efflux family protein, putative 0.0021 0.0064 0.1022
Mycobacterium ulcerans ion transport protein 0.0037 0.0237 0.0621
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0008 0.0126
Brugia malayi hypothetical protein 0.0037 0.0237 0.0344
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0237 0.3757
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.0237 0.0237
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0343 0.4105
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0172 0.176 0.2559
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0835 0.0835
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0019 0.009
Mycobacterium ulcerans transmembrane cation transporter 0.0037 0.0237 0.0621
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0037 0.0237 0.0344
Brugia malayi follicle stimulating hormone receptor 0.0495 0.5411 0.7868
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0126
Echinococcus granulosus potassium channel subfamily K 8 0.0037 0.0237 0.0237
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0343 0.0433
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Leishmania major hypothetical protein, conserved 0.0021 0.0064 0.1022
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0172 0.176 0.176
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0196 0.0196
Schistosoma mansoni terminal deoxycytidyl transferase 0.0016 0.0003 0.0003
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.019 0.1972 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0039
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0072 0.063 1
Leishmania major DNA polymerase eta, putative 0.0016 0.0003 0.005
Schistosoma mansoni hypothetical protein 0.0902 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.009 0.0835 0.0835
Brugia malayi Cation transporter family protein 0.0426 0.4628 0.6729
Schistosoma mansoni nAChR subunit 0.0079 0.0717 0.0717
Loa Loa (eye worm) carboxylesterase 0.0055 0.0446 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Onchocerca volvulus 0.0426 0.4628 0.5858
Loa Loa (eye worm) hypothetical protein 0.0347 0.3735 0.3735
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0172 0.176 0.2559
Mycobacterium tuberculosis Probable aminotransferase 0.0083 0.076 0.4172
Trypanosoma cruzi ion transport protein, putative 0.0037 0.0237 0.3757
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0356 0.1947
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0226 0.0284
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0008 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis beta LACTamase domain containing family member 0.0028 0.0135 0.0135
Echinococcus granulosus neutral alpha glucosidase AB 0.0027 0.0129 0.0129
Leishmania major hypothetical protein, conserved 0.0037 0.0237 0.3757
Brugia malayi Cation transporter family protein 0.0172 0.176 0.2559
Mycobacterium tuberculosis Conserved protein 0.0028 0.0135 0.0728
Trichomonas vaginalis sucrase-isomaltase, putative 0.0027 0.0129 0.0161
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0019 0.009
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0033 0.0196 0.0196
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0028
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0019 0.0043
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.1175 0.646
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.0237 0.0237
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0135 0.162
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0172 0.176 0.176
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0019 0.009
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Echinococcus multilocularis carboxylesterase 5A 0.0055 0.0446 0.0446
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0033 0.0196 0.0196
Echinococcus multilocularis glycine receptor subunit beta 0.0172 0.176 0.176
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0039 0.0039
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0037 0.0237 0.3757
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0326 0.3503 0.3503
Brugia malayi hypothetical protein 0.0232 0.2443 0.3552
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0172 0.176 0.2559
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.002 0.0043 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0019 0.009
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.0486 0.0486
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.1039 0.5712
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0049 0.0049
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0019 0.009
Loa Loa (eye worm) beta-lactamase 0.0028 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Loa Loa (eye worm) LGC-31 protein 0.0172 0.176 0.176
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0028 0.0135 0.0728
Trichomonas vaginalis esterase, putative 0.0028 0.0135 0.0168
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0237 0.0298
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0126
Onchocerca volvulus 0.0712 0.7852 1
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0247 0.0247
Entamoeba histolytica hypothetical protein 0.0019 0.0039 0.0184
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0356 0.0356
Mycobacterium tuberculosis Conserved protein 0.0028 0.0135 0.0728
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.0051
Echinococcus multilocularis 0.0017 0.0019 0.0019
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0019 0.0233
Loa Loa (eye worm) GABA receptor subunit 0.0092 0.0866 0.0866
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0092 0.0866 0.126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0486 0.0486
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0151 0.0151
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0037 0.0237 0.0237
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0479 0.5232 0.5232
Toxoplasma gondii hypothetical protein 0.0029 0.0151 0.1812
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Plasmodium vivax potassium channel, putative 0.0037 0.0237 0.2835
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0037 0.0237 0.0237
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0092 0.0866 0.126
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Leishmania major hypothetical protein, conserved 0.0021 0.0064 0.1022
Brugia malayi hypothetical protein 0.0019 0.0039 0.0057
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0356 0.0356
Loa Loa (eye worm) cytochrome P450 0.0017 0.0019 0.0019
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0037 0.0237 0.0344
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Brugia malayi hypothetical protein 0.0019 0.0039 0.0057
Schistosoma mansoni alpha-glucosidase 0.0105 0.101 0.101
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0172 0.176 0.2559
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0092 0.0866 0.0866
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0033 0.0196 0.0196
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0037 0.0237 0.1288
Mycobacterium ulcerans esterase/lipase LipP 0.0028 0.0135 0.0351
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0008 0.0095
Entamoeba histolytica hypothetical protein 0.0019 0.0039 0.0184
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0016 0.0003 0.005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0343 0.4105
Loa Loa (eye worm) hypothetical protein 0.009 0.0835 0.0835
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0049 0.0072
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0019 0.009
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0008
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0172 0.176 0.176
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.1039 0.5712
Loa Loa (eye worm) hypothetical protein 0.0479 0.5232 0.5232
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Onchocerca volvulus 0.0092 0.0866 0.1027
Onchocerca volvulus 0.0037 0.0237 0.0218
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0037 0.0237 0.0237
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0064 0.1022
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0008 0.0126
Loa Loa (eye worm) uncoordinated protein 58 0.0037 0.0237 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0226 0.0284
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0196 0.0196
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0135 0.2147
Onchocerca volvulus 0.0028 0.0135 0.0087
Schistosoma mansoni alpha-glucosidase 0.0105 0.101 0.101
Echinococcus granulosus carboxylesterase 5A 0.0055 0.0446 0.0446
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0172 0.176 0.176
Brugia malayi Cytochrome P450 family protein 0.0029 0.0151 0.022
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0019 0.0043
Echinococcus granulosus expressed protein 0.0373 0.4031 0.4031
Onchocerca volvulus 0.0028 0.0135 0.0087
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0046
Schistosoma mansoni lipoxygenase 0.0041 0.0284 0.0284
Leishmania major calcium/potassium channel (CAKC), putative 0.0037 0.0237 0.3757
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0072 0.063 0.063
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0039 0.0057
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0039 0.0039
Toxoplasma gondii thioredoxin reductase 0.0047 0.0356 0.4267
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0039 0.0039
Echinococcus multilocularis nAChR subunit 0.0092 0.0866 0.0866
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Onchocerca volvulus 0.0071 0.0621 0.0711
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0172 0.176 0.2559
Schistosoma mansoni multidrug resistance protein 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0135
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0247 0.3926
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0196 0.0196
Loa Loa (eye worm) acetylcholine receptor protein 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Loa Loa (eye worm) calcium channel 0.0033 0.0196 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0046
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0019 0.0043
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0172 0.176 0.176
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0064 0.1022
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.009 0.0835 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0172 0.176 0.2559
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Brugia malayi beta-lactamase family protein 0.0028 0.0135 0.0197
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0039 0.0039
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0008 0.0126
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0037 0.0237 0.0344
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0798 0.0798
Loa Loa (eye worm) hypothetical protein 0.0021 0.0063 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0129 0.205
Mycobacterium ulcerans glutaminase 0.0349 0.3765 1
Echinococcus multilocularis musashi 0.0022 0.0067 0.0067
Echinococcus granulosus lysosomal alpha glucosidase 0.0122 0.1202 0.1202
Mycobacterium ulcerans hypothetical protein 0.0083 0.076 0.2011
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0172 0.176 0.176
Echinococcus granulosus beta LACTamase domain containing family member 0.0028 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus granulosus glycine receptor subunit alpha 1 0.0172 0.176 0.176
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0092 0.0866 0.0866
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0135 0.1002
Mycobacterium tuberculosis Probable reductase 0.0108 0.1039 0.5712
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0135 0.2147
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0037 0.0237 0.0344
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0037 0.0237 0.0237
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0039 0.0046
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0237 0.0298
Plasmodium falciparum thioredoxin reductase 0.0047 0.0356 1
Mycobacterium ulcerans beta-lactamase 0.0028 0.0135 0.0351
Loa Loa (eye worm) hypothetical protein 0.015 0.1517 0.1517
Loa Loa (eye worm) hypothetical protein 0.0317 0.34 0.34
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0172 0.176 0.176
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.1175 0.646
Mycobacterium tuberculosis Probable lipase LipD 0.0028 0.0135 0.0728
Echinococcus granulosus calcium activated potassium channel variant 0.0037 0.0237 0.0237
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0129 0.0161
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0039 0.0057
Echinococcus granulosus geminin 0.049 0.5351 0.5351
Mycobacterium ulcerans hypothetical protein 0.0028 0.0135 0.0351
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0003 0.005
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0309
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0028 0.0135 0.0351
Schistosoma mansoni cytochrome P450 0.0017 0.0019 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0003 0.005
Toxoplasma gondii ABC1 family protein 0.0028 0.0135 0.162
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0008 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0028 0.0135 0.0728
Echinococcus granulosus potassium channel subfamily K 8 0.0037 0.0237 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0019 0.009
Schistosoma mansoni calcium-activated potassium channel 0.0715 0.7893 0.7893
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0079 0.0717 0.0717
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Onchocerca volvulus 0.0037 0.0237 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0039
Trypanosoma brucei unspecified product 0.0016 0.0003 0.005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0039 0.0039
Brugia malayi hypothetical protein 0.0079 0.0717 0.1042
Echinococcus multilocularis lamin dm0 0.0022 0.0067 0.0067
Brugia malayi Cation transporter family protein 0.0172 0.176 0.2559
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.1039 0.8826
Echinococcus granulosus dna polymerase kappa 0.0016 0.0003 0.0003
Brugia malayi excitatory GABA receptor EXP-1A 0.0172 0.176 0.2559
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0019 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0019 0.009
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0356 0.0356
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0172 0.176 0.176
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0019 0.009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0054 0.0433 0.2182
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0028 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0039
Brugia malayi hypothetical protein 0.0079 0.0717 0.1042
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Brugia malayi hypothetical protein 0.0122 0.1196 0.1738
Entamoeba histolytica hypothetical protein 0.0092 0.0866 0.4386
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0129 0.0161
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0013
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0092 0.0866 0.126
Brugia malayi Carboxylesterase family protein 0.0055 0.0446 0.0648
Echinococcus granulosus nAChR subunit 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0019 0.009
Onchocerca volvulus 0.0037 0.0237 0.0218
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.1039 0.5712
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0003 0.005
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Echinococcus granulosus acetylcholinesterase 0.0055 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Loa Loa (eye worm) glutathione reductase 0.0047 0.0356 0.0356
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0237 0.3757
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Loa Loa (eye worm) glutaminase 0.0349 0.3765 0.3765
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Leishmania major DNA polymerase kappa, putative 0.0016 0.0003 0.005
Schistosoma mansoni DNA polymerase eta 0.0016 0.0003 0.0003
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0479 0.5232 0.5232
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0172 0.176 0.176
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0177 0.1817 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0055 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0172 0.176 0.176
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Brugia malayi Cytochrome P450 family protein 0.0038 0.0247 0.036
Schistosoma mansoni hypothetical protein 0.049 0.5351 0.5351
Echinococcus granulosus twik family of potassium channels 0.0037 0.0237 0.0237
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0037 0.0237 0.0237
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0172 0.176 0.2559
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis lysosomal alpha glucosidase 0.0122 0.1202 0.1202
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0835 0.0835
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0343 0.0433
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0196 0.0196
Trypanosoma cruzi membrane transporter protein, putative 0.0021 0.0064 0.1022
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0019 0.0043
Schistosoma mansoni neurotransmitter gated ion channel 0.0079 0.0717 0.0717
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0039 0.0039
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0008 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0019 0.009
Echinococcus multilocularis potassium channel subfamily K 8 0.0037 0.0237 0.0237
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Trypanosoma brucei glucosidase, putative 0.0027 0.0129 0.205
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0426 0.4628 0.4628
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0129 0.0161
Echinococcus granulosus c-Jun N-terminal kinases 0.0326 0.3503 0.3503
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0003 0.005
Trypanosoma cruzi ion transport protein, putative 0.0037 0.0237 0.3757
Brugia malayi beta-lactamase 0.0028 0.0135 0.0197
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0039 0.0039
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0172 0.176 0.176
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Schistosoma mansoni microtubule-associated protein tau 0.045 0.4896 0.4896
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0486 0.0486
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0039 0.0039
Trypanosoma cruzi polo-like protein kinase, putative 0.0072 0.063 1
Trichomonas vaginalis D-aminoacylase, putative 0.0028 0.0135 0.0168
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0835 0.0835
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0033 0.0196 0.0285
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Mycobacterium tuberculosis Probable esterase LipL 0.0028 0.0135 0.0728
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0479 0.5232 0.5232
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0019 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0046
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0008 0.0126
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0019 0.0043
Plasmodium falciparum potassium channel 0.0037 0.0237 0.6645
Mycobacterium leprae Probable lipase LipE 0.0028 0.0135 0.1002
Echinococcus multilocularis acetylcholinesterase 0.0055 0.0446 0.0446
Schistosoma mansoni intermediate filament proteins 0.0022 0.0067 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0049 0.0049
Brugia malayi hypothetical protein 0.0037 0.0237 0.0344
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0247 0.0649
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Leishmania major hypothetical protein, conserved 0.0037 0.0237 0.3757
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0172 0.176 0.2559
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0479 0.5232 0.5232
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Loa Loa (eye worm) hypothetical protein 0.0022 0.0067 0.0067
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0039 0.0039
Onchocerca volvulus Putative nachr subunit 0.0479 0.5232 0.6634
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.1039 0.5712
Loa Loa (eye worm) TWK-7 protein 0.0037 0.0237 0.0237
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0033 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0232 0.2443 0.2443
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0037 0.0237 0.0344
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0172 0.176 0.2559
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0482 0.0482
Onchocerca volvulus 0.0232 0.2443 0.3051
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0343 0.4105
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0064 0.1022
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0039 0.0039
Plasmodium falciparum potassium channel 0.0037 0.0237 0.6645
Onchocerca volvulus 0.0426 0.4628 0.5858
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0039 0.0039
Schistosoma mansoni voltage-gated cation channel 0.0033 0.0196 0.0196
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0019 0.0043
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0037 0.0237 0.0237
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0039 0.0039
Trichomonas vaginalis set domain proteins, putative 0.0712 0.7852 1
Schistosoma mansoni alpha glucosidase 0.0027 0.0129 0.0129
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0237 0.0237
Schistosoma mansoni calcium-activated potassium channel 0.0902 1 1
Schistosoma mansoni nAChR subunit 0.0079 0.0717 0.0717
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0196 0.0196
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0019 0.0043
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Giardia lamblia DNA repair protein RAD52 0.019 0.1965 0.9968
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0237 0.0298
Trypanosoma brucei membrane transporter protein, putative 0.0021 0.0064 0.1022
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0064 0.1022
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0037 0.0237 0.3757
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0019 0.009
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0037 0.0237 0.0344
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0039 0.0039
Echinococcus granulosus potassium channel subfamily K 0.0037 0.0237 0.0237
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0426 0.4628 0.4628
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0129 0.0161
Loa Loa (eye worm) glutaminase 2 0.0349 0.3765 0.3765
Plasmodium vivax glutathione reductase, putative 0.0047 0.0356 0.4267
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0033 0.0196 0.3115
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0039 0.0039
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0083 0.076 0.0964
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0196 0.0196
Echinococcus granulosus glycine receptor subunit alpha 1 0.0172 0.176 0.176
Echinococcus granulosus glycine receptor subunit alpha 1 0.0172 0.176 0.176
Plasmodium falciparum glutathione reductase 0.0016 0.0008 0.0222
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0172 0.176 0.2559
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0172 0.176 0.2559
Trypanosoma brucei polo-like protein kinase 0.0072 0.063 1
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0039 0.0039
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0037 0.0237 0.0344
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0247 0.3926
Schistosoma mansoni lamin 0.0022 0.0067 0.0067
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0037 0.0237 0.0344
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0037 0.0237 0.0344
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0028 0.0135 0.0728
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0028 0.0135 0.0135
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0079 0.0717 0.0717
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0486 0.0486
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0067 0.0067
Onchocerca volvulus 0.009 0.0835 0.0986
Brugia malayi PXA domain containing protein 0.0019 0.0039 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0135 0.2147
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0135
Mycobacterium tuberculosis Conserved protein 0.0028 0.0135 0.0728
Brugia malayi beta-lactamase family protein 0.0028 0.0135 0.0197
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0008 0.5
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0309
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0129 0.064
Leishmania major cytochrome p450-like protein 0.0038 0.0247 0.3926
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0037 0.0237 0.1187
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0049 0.0049
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0486 0.0486
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0356 0.5654
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0019 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0129 0.0161
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0172 0.176 0.176
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0172 0.176 0.176
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0717 0.1042
Schistosoma mansoni glutaminase 0.0349 0.3765 0.3765
Schistosoma mansoni hypothetical protein 0.0016 0.0002 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0028 0.0135 0.0168
Echinococcus multilocularis geminin 0.049 0.5351 0.5351
Leishmania major potassium channel subunit-like protein 0.0037 0.0237 0.3757
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0019 0.0043
Onchocerca volvulus 0.0079 0.0717 0.0834
Loa Loa (eye worm) hypothetical protein 0.0033 0.0196 0.0196
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0008 0.0095
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0479 0.5232 0.5232
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0172 0.176 0.2559
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0079 0.0717 0.0717
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0037 0.0237 0.0237
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0093 0.0873 0.7384
Onchocerca volvulus 0.0079 0.0717 0.0834
Schistosoma mansoni hypothetical protein 0.049 0.5351 0.5351
Echinococcus multilocularis potassium channel subfamily K 0.0037 0.0237 0.0237
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0039 0.0039
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0028 0.0135 0.0135
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0482 0.0482
Trypanosoma brucei calcium-activated potassium channel, putative 0.0037 0.0237 0.3757
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0039
Brugia malayi PXA domain containing protein 0.0019 0.0039 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0046
Plasmodium vivax potassium channel, putative 0.0037 0.0237 0.2835
Loa Loa (eye worm) hypothetical protein 0.0338 0.364 0.364
Loa Loa (eye worm) hypothetical protein 0.0902 1 1
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0039 0.0039
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.019 0.1972 1
Schistosoma mansoni hypothetical protein 0.0037 0.0237 0.0237
Loa Loa (eye worm) voltage-dependent calcium channel 0.0033 0.0196 0.0196
Onchocerca volvulus Serine\/threonine kinase homolog 0.0072 0.063 0.0723
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Schistosoma mansoni biogenic amine (5HT) receptor 0.0417 0.4524 0.4524
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0172 0.176 0.176
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0037 0.0237 0.0344
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0172 0.176 0.176
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0343 0.0343
Echinococcus granulosus glycine receptor subunit beta 0.0172 0.176 0.176
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0129 0.0188
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0019 0.0309
Brugia malayi Pre-SET motif family protein 0.009 0.0835 0.1214
Loa Loa (eye worm) hypothetical protein 0.0377 0.4076 0.4076
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.0717
Brugia malayi jmjC domain containing protein 0.0059 0.0486 0.0707
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0008 0.0095
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0092 0.0866 0.126
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0486 0.0486
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Schistosoma mansoni lamin 0.0022 0.0067 0.0067
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.1039 0.5712
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Loa Loa (eye worm) ACC-1 protein 0.0172 0.176 0.176
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0625 0.6878 0.6878
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0479 0.5232 0.7607
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0157 0.159 0.159
Loa Loa (eye worm) acetylcholinesterase 1 0.0055 0.0446 0.0446
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0008 0.0126
Treponema pallidum fructose-bisphosphate aldolase 0.019 0.1972 1
Plasmodium vivax SET domain protein, putative 0.009 0.0835 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0019 0.009
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0717 0.1042
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0008 0.0024
Echinococcus multilocularis expressed protein 0.0373 0.4031 0.4031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0008 0.5
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.019 0.1972 0.2508
Loa Loa (eye worm) hypothetical protein 0.0172 0.176 0.176
Leishmania major hypothetical protein, conserved 0.0028 0.0135 0.2147
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0093 0.0873 0.4794
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.1175 1
Schistosoma mansoni acetylcholine receptor-related 0.0079 0.0717 0.0717
Toxoplasma gondii ion channel protein 0.0037 0.0237 0.2835
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0039 0.0039
Echinococcus granulosus microtubule associated protein 2 0.045 0.4896 0.4896
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0039 0.0039
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0008
Plasmodium falciparum glutathione reductase 0.0047 0.0356 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0135
Brugia malayi Pre-SET motif family protein 0.0625 0.6878 1
Echinococcus multilocularis dna polymerase eta 0.0016 0.0003 0.0003
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0008 0.0006
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0083 0.076 0.2011
Brugia malayi serine/threonine-protein kinase plk-2 0.0072 0.063 0.0916
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0019 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.0028 0.0135 0.0168
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0309
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.063 0.0799
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0717 0.1042
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0033 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0092 0.0866 0.0866
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0019 0.009
Echinococcus granulosus glycine receptor subunit beta 0.0172 0.176 0.176
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0083 0.076 0.6408
Leishmania major alpha glucosidase II subunit, putative 0.0027 0.0129 0.205
Schistosoma mansoni nAChR subunit 0.0172 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0079 0.0717 0.0717
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0008 0.0013
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0037 0.0237 0.0344
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0008 0.0013
Entamoeba histolytica hypothetical protein 0.0054 0.0433 0.2182
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0079 0.0717 0.0717
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0003 0.005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0072 0.063 0.3185
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0172 0.176 0.2559
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0067 0.0098
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0479 0.5232 0.5232
Loa Loa (eye worm) hypothetical protein 0.0033 0.0196 0.0196
Brugia malayi glutaminase DH11.1 0.0349 0.3765 0.5475
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0028 0.0135 0.0728
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0237 0.0237
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0008 0.0126
Echinococcus multilocularis small conductance calcium activated potassium 0.0902 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0027 0.0129 0.0129
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0033 0.0196 0.3115
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0172 0.176 0.2559
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0008 0.0126
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0039 0.0039
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0037 0.0237 0.0344
Onchocerca volvulus 0.0092 0.0866 0.1027

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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